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assertion_content_comment(nartR('cwJobFn','mobBackupTapeManager'),s("The","collection","of","all","the","jobs","of","backup","tape","manager",".","A","type","of","#$","WorkAgreement","."),3011847). assertion_content_comment(nartR('cwJobFn','mobBaggagePorter'),s("The","collection","of","all","the","jobs","of","porter",".","A","type","of","#$","WorkAgreement","."),3011949). assertion_content_comment(nartR('cwJobFn','mobBartender'),s("The","collection","of","all","the","jobs","of","bartender",".","A","type","of","#$","WorkAgreement","."),3011849). assertion_content_comment(nartR('cwJobFn','mobBenefitsAdministrator'),s("The","collection","of","all","the","jobs","of","benefits","administrator",".","A","type","of","#$","WorkAgreement","."),3011850). assertion_content_comment(nartR('cwJobFn','mobBondsTrader'),s("The","collection","of","all","the","jobs","of","bond","trader",".","A","type","of","#$","WorkAgreement","."),3011852). assertion_content_comment(nartR('cwJobFn','mobBouncer'),s("The","collection","of","all","the","jobs","of","bouncer",".","A","type","of","#$","WorkAgreement","."),3011854). assertion_content_comment(nartR('cwJobFn','mobBuildingConstructor'),s("The","collection","of","all","the","jobs","of","building","constructor",".","A","type","of","#$","WorkAgreement","."),3011855). assertion_content_comment(nartR('cwJobFn','mobBusDriver'),s("The","collection","of","all","the","jobs","of","bus","driver",".","A","type","of","#$","WorkAgreement","."),3011856). assertion_content_comment(nartR('cwJobFn','mobButcher'),s("The","collection","of","all","the","jobs","of","butcher",".","A","type","of","#$","WorkAgreement","."),3011857). assertion_content_comment(nartR('cwJobFn','mobBuyerProfessional'),s("The","collection","of","all","the","jobs","of","professional","buyer",".","A","type","of","#$","WorkAgreement","."),3011951). assertion_content_comment(nartR('cwJobFn','mobCarDealer'),s("The","collection","of","all","the","jobs","of","car","salesman",".","A","type","of","#$","WorkAgreement","."),3011859). assertion_content_comment(nartR('cwJobFn','mobCardiologist'),s("The","collection","of","all","the","jobs","of","cardiologist",".","A","type","of","#$","WorkAgreement","."),3011861). assertion_content_comment(nartR('cwJobFn','mobCarMechanic'),s("The","collection","of","all","the","jobs","of","automobile","mechanic",".","A","type","of","#$","WorkAgreement","."),3011846). assertion_content_comment(nartR('cwJobFn','mobCarWasher'),s("The","collection","of","all","the","jobs","of","car","washer",".","A","type","of","#$","WorkAgreement","."),3011860). assertion_content_comment(nartR('cwJobFn','mobCashier'),s("The","collection","of","all","the","jobs","of","cashier",".","A","type","of","#$","WorkAgreement","."),3011862). assertion_content_comment(nartR('cwJobFn','mobCertifiedPublicAccountant'),s("The","collection","of","all","the","jobs","of","certified","public","accountant",".","A","type","of","#$","WorkAgreement","."),3011863). assertion_content_comment(nartR('cwJobFn','mobChauffeur'),s("The","collection","of","all","the","jobs","of","chauffeur",".","A","type","of","#$","WorkAgreement","."),3011864). assertion_content_comment(nartR('cwJobFn','mobChildcareWorker'),s("The","collection","of","all","the","jobs","of","child-care","worker",".","A","type","of","#$","WorkAgreement","."),3011866). assertion_content_comment(nartR('cwJobFn','mobCommercialSalesRepresentative'),s("The","collection","of","all","the","jobs","of","commercial","sales","rep",".","A","type","of","#$","WorkAgreement","."),3011869). assertion_content_comment(nartR('cwJobFn','mobCommoditiesTrader'),s("The","collection","of","all","the","jobs","of","commodities","trader",".","A","type","of","#$","WorkAgreement","."),3011870). assertion_content_comment(nartR('cwJobFn','mobComputerRepairPerson'),s("The","collection","of","all","the","jobs","of","computer","repair","person",".","A","type","of","#$","WorkAgreement","."),3011872). assertion_content_comment(nartR('cwJobFn','mobCounselingPsychologist'),s("The","collection","of","all","the","jobs","of","counseling","psychologist",".","A","type","of","#$","WorkAgreement","."),3011877). assertion_content_comment(nartR('cwJobFn','mobCreditManager'),s("The","collection","of","all","the","jobs","of","credit","manager",".","A","type","of","#$","WorkAgreement","."),3011878). assertion_content_comment(nartR('cwJobFn','mobCrewMemberOnShip'),s("The","collection","of","all","the","jobs","of","sailor",".","A","type","of","#$","WorkAgreement","."),3011967). assertion_content_comment(nartR('cwJobFn','mobDataEntryPerson'),s("The","collection","of","all","the","jobs","of","data","entry","worker",".","A","type","of","#$","WorkAgreement","."),3011881). assertion_content_comment(nartR('cwJobFn','mobDeliveryPerson'),s("The","collection","of","all","the","jobs","of","deliveryman",".","A","type","of","#$","WorkAgreement","."),3011882). assertion_content_comment(nartR('cwJobFn','mobDesigner'),s("The","collection","of","all","the","jobs","of","designer",".","A","type","of","#$","WorkAgreement","."),3011884). assertion_content_comment(nartR('cwJobFn','mobDoctorMedical'),s("The","collection","of","all","the","jobs","of","doctor",".","A","type","of","#$","WorkAgreement","."),3011886). assertion_content_comment(nartR('cwJobFn','mobDressmakerProfessional'),s("The","collection","of","all","the","jobs","of","dressmaker",".","A","type","of","#$","WorkAgreement","."),3011973). assertion_content_comment(nartR('cwJobFn','mobEditor'),s("The","collection","of","all","the","jobs","of","editor",".","A","type","of","#$","WorkAgreement","."),3011887). assertion_content_comment(nartR('cwJobFn','mobEmergencyMedicalTechnician'),s("The","collection","of","all","the","jobs","of","paramedic",".","A","type","of","#$","WorkAgreement","."),3011939). assertion_content_comment(nartR('cwJobFn','mobEngineer'),s("The","collection","of","all","the","jobs","of","engineer",".","A","type","of","#$","WorkAgreement","."),3011889). assertion_content_comment(nartR('cwJobFn','mobEquityTrader'),s("The","collection","of","all","the","jobs","of","equity","trader",".","A","type","of","#$","WorkAgreement","."),3011890). assertion_content_comment(nartR('cwJobFn','mobFarmer'),s("The","collection","of","all","the","jobs","of","farmer",".","A","type","of","#$","WorkAgreement","."),3011893). assertion_content_comment(nartR('cwJobFn','mobFarmWorker'),s("The","collection","of","all","the","jobs","of","farm","worker",".","A","type","of","#$","WorkAgreement","."),3011892). assertion_content_comment(nartR('cwJobFn','mobFinancialAnalyst'),s("The","collection","of","all","the","jobs","of","financial","analyst",".","A","type","of","#$","WorkAgreement","."),3011894). assertion_content_comment(nartR('cwJobFn','mobFirefighter'),s("The","collection","of","all","the","jobs","of","firefighter",".","A","type","of","#$","WorkAgreement","."),3011895). assertion_content_comment(nartR('cwJobFn','mobFirstMate'),s("The","collection","of","all","the","jobs","of","first","mate",".","A","type","of","#$","WorkAgreement","."),3011896). assertion_content_comment(nartR('cwJobFn','mobFlightAttendant'),s("The","collection","of","all","the","jobs","of","flight","attendant",".","A","type","of","#$","WorkAgreement","."),3011897). assertion_content_comment(nartR('cwJobFn','mobFlorist'),s("The","collection","of","all","the","jobs","of","florist",".","A","type","of","#$","WorkAgreement","."),3011898). assertion_content_comment(nartR('cwJobFn','mobFoodDeliveryPerson'),s("The","collection","of","all","the","jobs","of","food","delivery","person",".","A","type","of","#$","WorkAgreement","."),3011899). assertion_content_comment(nartR('cwJobFn','mobForeignExchangeTrader'),s("The","collection","of","all","the","jobs","of","foreign","exchange","trader",".","A","type","of","#$","WorkAgreement","."),3011900). assertion_content_comment(nartR('cwJobFn','mobForester'),s("The","collection","of","all","the","jobs","of","forester",".","A","type","of","#$","WorkAgreement","."),3011902). assertion_content_comment(nartR('cwJobFn','mobForestRanger'),s("The","collection","of","all","the","jobs","of","forest","ranger",".","A","type","of","#$","WorkAgreement","."),3011901). assertion_content_comment(nartR('cwJobFn','mobFuturesOptionsTrader'),s("The","collection","of","all","the","jobs","of","futures","and","options","trader",".","A","type","of","#$","WorkAgreement","."),3011903). assertion_content_comment(nartR('cwJobFn','mobGeneralPractitioner'),s("The","collection","of","all","the","jobs","of","general","practitioner",".","A","type","of","#$","WorkAgreement","."),3011904). assertion_content_comment(nartR('cwJobFn','mobGeriatricDoctor'),s("The","collection","of","all","the","jobs","of","geriatrician",".","A","type","of","#$","WorkAgreement","."),3011907). assertion_content_comment(nartR('cwJobFn','mobGynecologist'),s("The","collection","of","all","the","jobs","of","gynecologist",".","A","type","of","#$","WorkAgreement","."),3011908). assertion_content_comment(nartR('cwJobFn','mobHairStylist'),s("The","collection","of","all","the","jobs","of","hairstylist",".","A","type","of","#$","WorkAgreement","."),3011909). assertion_content_comment(nartR('cwJobFn','mobHandyman'),s("The","collection","of","all","the","jobs","of","handyman",".","A","type","of","#$","WorkAgreement","."),3011910). assertion_content_comment(nartR('cwJobFn','mobHousekeeper'),s("The","collection","of","all","the","jobs","of","housekeeper",".","A","type","of","#$","WorkAgreement","."),3011912). assertion_content_comment(nartR('cwJobFn','mobIndividualCustomerSalesRepresentative'),s("The","collection","of","all","the","jobs","of","sales","rep","to","individual","customer",".","A","type","of","#$","WorkAgreement","."),3011970). assertion_content_comment(nartR('cwJobFn','mobInternist'),s("The","collection","of","all","the","jobs","of","internist",".","A","type","of","#$","WorkAgreement","."),3011913). assertion_content_comment(nartR('cwJobFn','mobInventoryBuyingAgent'),s("The","collection","of","all","the","jobs","of","inventory","buying","agent",".","A","type","of","#$","WorkAgreement","."),3011914). assertion_content_comment(nartR('cwJobFn','mobInventoryBuyingManager'),s("The","collection","of","all","the","jobs","of","inventory","buying","manager",".","A","type","of","#$","WorkAgreement","."),3011915). assertion_content_comment(nartR('cwJobFn','mobJanitor'),s("The","collection","of","all","the","jobs","of","janitor",".","A","type","of","#$","WorkAgreement","."),3011879). assertion_content_comment(nartR('cwJobFn','mobLawyer'),s("The","collection","of","all","the","jobs","of","lawyer",".","A","type","of","#$","WorkAgreement","."),3011919). assertion_content_comment(nartR('cwJobFn','mobLibrarian'),s("The","collection","of","all","the","jobs","of","librarian",".","A","type","of","#$","WorkAgreement","."),3011920). assertion_content_comment(nartR('cwJobFn','mobLifeguard'),s("The","collection","of","all","the","jobs","of","lifeguard",".","A","type","of","#$","WorkAgreement","."),3011921). assertion_content_comment(nartR('cwJobFn','mobMaid'),s("The","collection","of","all","the","jobs","of","maid",".","A","type","of","#$","WorkAgreement","."),3011923). assertion_content_comment(nartR('cwJobFn','mobMailCarrier'),s("The","collection","of","all","the","jobs","of","mailman",".","A","type","of","#$","WorkAgreement","."),3011924). assertion_content_comment(nartR('cwJobFn','mobManager'),s("The","collection","of","all","the","jobs","of","manager",".","A","type","of","#$","WorkAgreement","."),3011925). assertion_content_comment(nartR('cwJobFn','mobMarketingPerson'),s("The","collection","of","all","the","jobs","of","marketer",".","A","type","of","#$","WorkAgreement","."),3011926). assertion_content_comment(nartR('cwJobFn','mobMatador'),s("The","collection","of","all","the","jobs","of","matador",".","A","type","of","#$","WorkAgreement","."),3011927). assertion_content_comment(nartR('cwJobFn','mobMedicalCareProfessional'),s("The","collection","of","all","the","jobs","of","medical","care","professional",".","A","type","of","#$","WorkAgreement","."),3011929). assertion_content_comment(nartR('cwJobFn','mobMetalRefinisher'),s("The","collection","of","all","the","jobs","of","metal","refinisher",".","A","type","of","#$","WorkAgreement","."),3011930). assertion_content_comment(nartR('cwJobFn','mobMidLevelManager'),s("The","collection","of","all","the","jobs","of","mid-level","manager",".","A","type","of","#$","WorkAgreement","."),3011932). assertion_content_comment(nartR('cwJobFn','mobMovieProjectionist'),s("The","collection","of","all","the","jobs","of","projectionist",".","A","type","of","#$","WorkAgreement","."),3011955). assertion_content_comment(nartR('cwJobFn','mobNurse'),s("The","collection","of","all","the","jobs","of","nurse",".","A","type","of","#$","WorkAgreement","."),3011934). assertion_content_comment(nartR('cwJobFn','mobObstetrician'),s("The","collection","of","all","the","jobs","of","obstetrician",".","A","type","of","#$","WorkAgreement","."),3011935). assertion_content_comment(nartR('cwJobFn','mobOrthopaedist'),s("The","collection","of","all","the","jobs","of","orthopaedist",".","A","type","of","#$","WorkAgreement","."),3011938). assertion_content_comment(nartR('cwJobFn','mobParkingLotAttendant'),s("The","collection","of","all","the","jobs","of","parking","lot","attendant",".","A","type","of","#$","WorkAgreement","."),3011940). assertion_content_comment(nartR('cwJobFn','mobPediatrician'),s("The","collection","of","all","the","jobs","of","pediatrician",".","A","type","of","#$","WorkAgreement","."),3011941). assertion_content_comment(nartR('cwJobFn','mobPersonalInjuryLawyer'),s("The","collection","of","all","the","jobs","of","personal","injury","lawyer",".","A","type","of","#$","WorkAgreement","."),3011942). assertion_content_comment(nartR('cwJobFn','mobPharmacist'),s("The","collection","of","all","the","jobs","of","pharmacist",".","A","type","of","#$","WorkAgreement","."),3011943). assertion_content_comment(nartR('cwJobFn','mobPlumber'),s("The","collection","of","all","the","jobs","of","plumber",".","A","type","of","#$","WorkAgreement","."),3011947). assertion_content_comment(nartR('cwJobFn','mobPresidentCorporateOfficer'),s("The","collection","of","all","the","jobs","of","corporate","president",".","A","type","of","#$","WorkAgreement","."),3011875). assertion_content_comment(nartR('cwJobFn','mobProfessor'),s("The","collection","of","all","the","jobs","of","professor",".","A","type","of","#$","WorkAgreement","."),3011953). assertion_content_comment(nartR('cwJobFn','mobProjectManager'),s("The","collection","of","all","the","jobs","of","project","manager",".","A","type","of","#$","WorkAgreement","."),3011954). assertion_content_comment(nartR('cwJobFn','mobPsychiatrist'),s("The","collection","of","all","the","jobs","of","psychiatrist",".","A","type","of","#$","WorkAgreement","."),3011980). assertion_content_comment(nartR('cwJobFn','mobPublicSectorEmployee'),s("The","collection","of","all","the","jobs","of","public","sector","worker",".","A","type","of","#$","WorkAgreement","."),3011957). assertion_content_comment(nartR('cwJobFn','mobPurchasingAgent'),s("The","collection","of","all","the","jobs","of","purchasing","agent",".","A","type","of","#$","WorkAgreement","."),3011958). assertion_content_comment(nartR('cwJobFn','mobPurchasingManager'),s("The","collection","of","all","the","jobs","of","purchasing","manager",".","A","type","of","#$","WorkAgreement","."),3011959). assertion_content_comment(nartR('cwJobFn','mobRadiologist'),s("The","collection","of","all","the","jobs","of","radiologist",".","A","type","of","#$","WorkAgreement","."),3011960). assertion_content_comment(nartR('cwJobFn','mobRealEstateAgent'),s("The","collection","of","all","the","jobs","of","real","estate","agent",".","A","type","of","#$","WorkAgreement","."),3011962). assertion_content_comment(nartR('cwJobFn','mobRefinisher'),s("The","collection","of","all","the","jobs","of","refinisher",".","A","type","of","#$","WorkAgreement","."),3011963). assertion_content_comment(nartR('cwJobFn','mobResearcher'),s("The","collection","of","all","the","jobs","of","researcher",".","A","type","of","#$","WorkAgreement","."),3011916). assertion_content_comment(nartR('cwJobFn','mobRetailCashier'),s("The","collection","of","all","the","jobs","of","retail","cashier",".","A","type","of","#$","WorkAgreement","."),3011964). assertion_content_comment(nartR('cwJobFn','mobRetailDepartmentManager'),s("The","collection","of","all","the","jobs","of","department","manager",".","A","type","of","#$","WorkAgreement","."),3011883). assertion_content_comment(nartR('cwJobFn','mobRetailSalesClerk'),s("The","collection","of","all","the","jobs","of","retail","sales","clerk",".","A","type","of","#$","WorkAgreement","."),3011965). assertion_content_comment(nartR('cwJobFn','mobRoadConstructor'),s("The","collection","of","all","the","jobs","of","road","worker",".","A","type","of","#$","WorkAgreement","."),3011966). assertion_content_comment(nartR('cwJobFn','mobSalesManager'),s("The","collection","of","all","the","jobs","of","sales","manager",".","A","type","of","#$","WorkAgreement","."),3011968). assertion_content_comment(nartR('cwJobFn','mobSalesPerson'),s("The","collection","of","all","the","jobs","of","salesperson",".","A","type","of","#$","WorkAgreement","."),3011971). assertion_content_comment(nartR('cwJobFn','mobSalesRepresentative'),s("The","collection","of","all","the","jobs","of","sales","rep",".","A","type","of","#$","WorkAgreement","."),3011969). assertion_content_comment(nartR('cwJobFn','mobScientist'),s("The","collection","of","all","the","jobs","of","scientist",".","A","type","of","#$","WorkAgreement","."),3011972). assertion_content_comment(nartR('cwJobFn','mobSecondMate'),s("The","collection","of","all","the","jobs","of","second","mate",".","A","type","of","#$","WorkAgreement","."),3011974). assertion_content_comment(nartR('cwJobFn','mobSecretary'),s("The","collection","of","all","the","jobs","of","secretary",".","A","type","of","#$","WorkAgreement","."),3011975). assertion_content_comment(nartR('cwJobFn','mobSecurityGuard'),s("The","collection","of","all","the","jobs","of","security","guard",".","A","type","of","#$","WorkAgreement","."),3011976). assertion_content_comment(nartR('cwJobFn','mobServiceStationAttendant'),s("The","collection","of","all","the","jobs","of","gas","station","attendant",".","A","type","of","#$","WorkAgreement","."),3011977). assertion_content_comment(nartR('cwJobFn','mobShelfStocker'),s("The","collection","of","all","the","jobs","of","stockboy",".","A","type","of","#$","WorkAgreement","."),3011985). assertion_content_comment(nartR('cwJobFn','mobShipCaptain'),s("The","collection","of","all","the","jobs","of","captain",".","A","type","of","#$","WorkAgreement","."),3011858). assertion_content_comment(nartR('cwJobFn','mobShippingReceivingClerk'),s("The","collection","of","all","the","jobs","of","shipping-receiving","clerk",".","A","type","of","#$","WorkAgreement","."),3011979). assertion_content_comment(nartR('cwJobFn','mobSocialWorker'),s("The","collection","of","all","the","jobs","of","social","worker",".","A","type","of","#$","WorkAgreement","."),3011982). assertion_content_comment(nartR('cwJobFn','mobSoldier'),s("The","collection","of","all","the","jobs","of","soldier",".","A","type","of","#$","WorkAgreement","."),3011983). assertion_content_comment(nartR('cwJobFn','mobStockbroker'),s("The","collection","of","all","the","jobs","of","market","broker",".","A","type","of","#$","WorkAgreement","."),3011984). assertion_content_comment(nartR('cwJobFn','mobStockroomWorker'),s("The","collection","of","all","the","jobs","of","stockroom","worker",".","A","type","of","#$","WorkAgreement","."),3011986). assertion_content_comment(nartR('cwJobFn','mobSurgeon'),s("The","collection","of","all","the","jobs","of","surgeon",".","A","type","of","#$","WorkAgreement","."),3011988). assertion_content_comment(nartR('cwJobFn','mobSystemsAnalyst'),s("The","collection","of","all","the","jobs","of","systems","analyst",".","A","type","of","#$","WorkAgreement","."),3011989). assertion_content_comment(nartR('cwJobFn','mobTailorProfessional'),s("The","collection","of","all","the","jobs","of","tailor",".","A","type","of","#$","WorkAgreement","."),3011990). assertion_content_comment(nartR('cwJobFn','mobTaxiDriver'),s("The","collection","of","all","the","jobs","of","taxi","driver",".","A","type","of","#$","WorkAgreement","."),3011991). assertion_content_comment(nartR('cwJobFn','mobTechnicalManager'),s("The","collection","of","all","the","jobs","of","technical","manager",".","A","type","of","#$","WorkAgreement","."),3011992). assertion_content_comment(nartR('cwJobFn','mobThirdMate'),s("The","collection","of","all","the","jobs","of","third","mate",".","A","type","of","#$","WorkAgreement","."),3011993). assertion_content_comment(nartR('cwJobFn','mobTicketSeller'),s("The","collection","of","all","the","jobs","of","ticket","seller",".","A","type","of","#$","WorkAgreement","."),3011994). assertion_content_comment(nartR('cwJobFn','mobTrader'),s("The","collection","of","all","the","jobs","of","trader",".","A","type","of","#$","WorkAgreement","."),3011996). 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assertion_content_comment(nartR('eventPositiveRegulationOfTypeFn','eventCellProliferation'),s("Any","process","that","activates","or","increases","the","rate","or","extent","of","cell","proliferation","."),4436901). assertion_content_comment(nartR('eventPositiveRegulationOfTypeFn','eventChondrocyteDifferentiation'),s("Any","process","that","activates","or","increases","the","frequency",",","rate","or","extent","of","chondrocyte","differentiation","."),4436310). assertion_content_comment(nartR('eventPositiveRegulationOfTypeFn','eventOsteoblastDifferentiation'),s("Any","process","that","activates","or","increases","the","frequency",",","rate","or","extent","of","osteoblast","differentiation","."),4437029). assertion_content_comment(nartR('eventPositiveRegulationOfTypeFn',nartR('eventProliferationOfCellTypeFn','tOsteoblast')),s("Any","process","that","activates","or","increases","the","rate","or","extent","of","osteoblast","proliferation","."),4436747). assertion_content_comment(nartR('eventPositiveRegulationOfTypeFn',nartR('eventProliferationOfCellTypeFn','tOsteoclast')),s("Any","process","that","increases","the","rate",",","frequency",",","or","extent","of","the","multiplication","or","reproduction","of","osteoclasts",",","resulting","in","the","expansion","of","an","osteoclast","cell","population","."),4436678). assertion_content_comment(nartR('eventProliferationOfCellTypeFn','tOsteoblast'),s("The","multiplication","or","reproduction","of","osteoblasts",",","resulting","in","the","expansion","of","an","osteoblast","cell","population",".","An","osteoblast","is","a","bone-forming","cell","which","secretes","an","extracellular","matrix",".","Hydroxyapatite","crystals","are","then","deposited","into","the","matrix","to","form","bone","."),4436718). 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assertion_content_comment(nartR('eventRegulationOfTypeFn','actBoneRemodeling'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","bone","remodeling",",","the","processes","of","bone","formation","and","resorption","that","combine","to","maintain","skeletal","integrity","."),4436101). assertion_content_comment(nartR('eventRegulationOfTypeFn','actBoneResorption'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","bone","tissue","loss","(","resorption",")"),4436172). 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assertion_content_comment(nartR('eventRegulationOfTypeFn','actCollagenSynthesis'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","the","chemical","reactions","and","pathways","resulting","in","the","formation","of","collagen",",","any","of","a","group","of","fibrous","proteins","of","very","high","tensile","strength","that","form","the","main","component","of","connective","tissue","in","animals","."),4436016). assertion_content_comment(nartR('eventRegulationOfTypeFn','actFiltrationAtRenalCorpuscle'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","glomerular","filtration",".","Glomerular","filtration","is","the","process","in","which","blood","is","filtered","by","the","glomerulus","into","the","renal","tubule","."),4436493). assertion_content_comment(nartR('eventRegulationOfTypeFn','eventCellProliferation'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","cell","proliferation","."),4436803). assertion_content_comment(nartR('eventRegulationOfTypeFn','eventChondrocyteDifferentiation'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","chondrocyte","differentiation","."),4436330). assertion_content_comment(nartR('eventRegulationOfTypeFn','eventOsteoblastDifferentiation'),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","osteoblast","differentiation","."),4437051). assertion_content_comment(nartR('eventRegulationOfTypeFn',nartR('eventProliferationOfCellTypeFn','tOsteoblast')),s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","osteoblast","proliferation","."),4436765). assertion_content_comment(nartR('eventRegulationOfTypeFn',nartR('eventProliferationOfCellTypeFn','tOsteoclast')),s("Any","process","that","modulates","the","rate",",","frequency",",","or","extent","of","the","multiplication","or","reproduction","of","osteoclasts",",","resulting","in","the","expansion","of","an","osteoclast","cell","population","."),4436706). assertion_content_comment(nartR('eventTransmissionOfRadiationTypeFn','eventMicrowaveRadiation'),s("The","collection","of","all","microwave","transmissions",".","A","type","of","#$","MicrowaveRadiation","and","#$","InformationBearingWavePropagation","."),3011504). assertion_content_comment(nartR('eventWaveEmissionFn','eventVisibleLight'),s("A","collection","of","events",";","a","specialization","of","#$","EmittingAWave",".","Each","instance","of","(","#$","WaveEmissionFn","#$","VisibleLight",")","is","an","event","in","which","an","instance","of","#$","VisibleLight","is","emitted","from","some","#$","waveSource",".","Examples",":","the","burning","of","a","candle",";","the","shining","of","a","light","bulb",";","a","firefly","'","s","glowing",".","Almost","every","instance","of","(","#$","WaveEmissionFn","#$","VisibleLight",")","will","also","emit","instances","of","types","of","#$","ElectromagneticRadiation","other","than","#$","VisibleLight","."),1070588). assertion_content_comment(nartR('eventWaveEmissionFn','eventVisibleLight'),s("The","collection","of","all","illumination",".","A","type","of","#$","EmittingAWave","."),3011402). assertion_content_comment(nartR('iAct_CycBasedFactGatheringProcessNamedFn',"organization-list-fet-20061110"),s("An","instance","of","#$","CycBasedFactGatheringProcess",".","The","KAGs","for","this","process","were","generated","using","KB","Queries","that","compute","the","KAGs","using","FET","templates",".","This","fact-gathering","process","was","run","on","a","Cyc","image","with","KB","921","and","System","1.11896",".","In","this","experiment",",","we","try","to","find","facts","for","10","organizations","(","5","commercial",",","5","terrorist",")"),2817227). assertion_content_comment(nartR('iAct_CycBasedFactGatheringProcessNamedFn',"politician-list-fet-20061109"),s("An","instance","of","#$","CycBasedFactGatheringProcess",".","The","KAGs","for","this","process","were","generated","using","KB","Queries","that","compute","the","KAGs","using","FET","templates",".","This","fact-gathering","process","was","run","on","a","Cyc","image","with","KB","920","and","System","1.11893",".","In","this","experiment",",","we","try","to","find","facts","for","2","politicians","."),2815742). assertion_content_comment(nartR('iAISForFn','iGLFTestGraph001'),s("An","internal","testing","graph",".","An","instance","of","#$","GLFGraph",".","(","#$","AISForFn","#$","GLFTestGraph001",")","is","the","graph","#$","CWInfoStructure","for","#$","GLFTestGraph001","."),1461117). assertion_content_comment(nartR('iboInformationThingAboutFn','cwMarriageLicense'),s("The","collection","of","all","marriage","licenses",".","A","type","of","#$","InformationBearingThing","."),3011465). assertion_content_comment(nartR('iboPicturesOfTypeFn',nartR('tColOfSubcollectionOfWithRelationToTypeFn','tBackSide','physicalParts','tSpatialThingLocalized')),s("The","collection","of","pictures","'","taken","from","behind","'","something",",","in","the","sense","that","they","are","pictures","of","a","#$","SpatialThing-Localized","that","are","taken","from","behind","the","thing",".","This","collection","does","not","include","pictures","which","may","have","been","taken","behind","a","#$","SpatialThing-Localized","but","which","are","not","of","the","#$","BackSide","of","any","#$","SpatialThing-Localized","(","i.e.",",","not","merely","location",",","but","location","and","subject","of","the","picture",")"),5020135). assertion_content_comment(nartR('iCentiFn','vMeterFn'),s("This","is","a","unit","of","length","derived","by","dividing","a","meter","by","100",";","see","also","#$","UnitOfMeasureWithPrefix","."),1086339). assertion_content_comment(nartR('iCodeTemplateNamedFn',"CLEAR"),s("The","CLEAR","template","put","the","value","NULL","into","a","register","or","memory","location","."),4525874). assertion_content_comment(nartR('iCodeTemplateNamedFn',"COPY"),s("The","COPY","template","puts","a","register","'","s","value","into","another","register","."),4525860). assertion_content_comment(nartR('iCodeTemplateNamedFn',"IGNORED"),s("The","IGNORED","template","gathers","up","unused","instructions","that","are","not","relevant","to","the","compilation","."),4525909). assertion_content_comment(nartR('iCodeTemplateNamedFn',"INVOKE"),s("The","INVOKE","template","invokes","a","function","on","an","assembled","list","of","arguments",":","the","result","can","be","discarded","or","placed","in","a","register","or","memory","location","other","than","the","result","register","."),4525895). assertion_content_comment(nartR('iCodeTemplateNamedFn',"IS_NULL"),s("The","IS_NULL","template","checks","a","register","against","NULL","."),4525881). assertion_content_comment(nartR('iCodeTemplateNamedFn',"PASSn"),s("The","PASSn","template","passes","a","value","as","the","n-th","argument","to","a","function","."),4525888). assertion_content_comment(nartR('iCodeTemplateNamedFn',"RETRIEVE"),s("The","RETRIEVE","template","puts","a","memory","location","'","s","value","into","a","register","."),4525867). assertion_content_comment(nartR('iCodeTemplateNamedFn',"RETVAL"),s("The","RETVAL","template","specifies","the","return","value","of","a","function","and","performs","the","exit","."),4525902). assertion_content_comment(nartR('iCodeTemplateNamedFn',"STORE"),s("The","STORE","template","puts","a","register","'","s","value","into","a","memory","location","."),4525853). assertion_content_comment(nartR('iCW_NationalAnthemFn','iGroup_UnitedStatesOfAmerica'),s("Star-spangled","Banner",":","the","#$","NationalAnthem","of","the","United","States","of","America","."),3011748). assertion_content_comment(nartR('iCW_SoftwareVersionFn','iGNUEnscriptAlphaTheProgram',"1.6.1-16.1"),s("I","'","m","not","sure","if","what","|","|","you","get","at","the","different","URLs","differs","in","any","way",".","I","am","assuming","not",",","since","the","|","|","version","no.s","are","the","same","."),887377). assertion_content_comment(nartR('iCW_SoftwareVersionFn','iGNUEnscriptAlphaTheProgram',"1.6.1-16.2"),s("Red","Hat","Linux","|","|","7.1","and","7.2","doesn","'","t","seem","to","have","an","alpha","version","of","this","one","."),887391). assertion_content_comment(nartR('iCW_SoftwareVersionFn','iGNUEnscriptIntel386TheProgram',"1.6.1-16.1"),s("I","'","m","not","sure","if","what","|","|","you","get","at","the","different","URLs","differs","in","any","way",".","I","am","assuming","not",",","since","the","|","|","version","no.s","are","the","same","."),887406). assertion_content_comment(nartR('iCW_SoftwareVersionFn','iGNUEnscriptIntel386TheProgram',"1.6.1-16.2"),s("I","'","m","not","sure","if","what","|","|","you","get","at","the","different","URLs","differs","in","any","way",".","I","am","assuming","not",",","since","the","|","|","version","no.s","are","the","same","."),887413). assertion_content_comment(nartR('iCW_SoftwareVersionFn','iGNUEnscriptSparcTheProgram',"1.6.1-16.1"),s("I","'","m","not","sure","if","what","|","|","you","get","at","the","different","URLs","differs","in","any","way",".","I","am","assuming","not",",","since","the","|","|","version","no.s","are","the","same","."),887446). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNEKBCTS2old'),s("0.002","Which","is","more","volatile",",","Sarin","or","VX","?"),1348511). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNE_KBCTS6_1'),s("6.1","Which","of","the","G-Series","nerve","agents","is","the","most","volatile","?"),1417496). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNE_KBCTS7_1'),s("0.007.1","What","substances","are","liquids","at","20","degrees","celsius","?"),1384543). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNE_KBCTS8_1'),s("0.008.1","Is","it","true","that","VX","is","more","toxic","to","inhale","than","Phosgene","Oxime","?"),1417123). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNE_KBCTS8_2'),s("0.008.2","Is","it","true","that","Phosgene","Oxime","is","not","more","toxic","to","inhale","than","VX","?"),1417124). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNEKBCTS8old'),s("0.008","Which","is","more","toxic","to","inhale",",","VX","or","Phosgene","Oxime","?"),1360670). assertion_content_comment(nartR('iCW_TestQueryFn','iCBRNE_KBCTS9_1'),s("0.009.1","What","is","the","IDLH","of","acetone","?"),1361259). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS3_1'),s("0.003.1","Where","have","which","known","terrorists","been","known","to","be","?"),1386440). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_1'),s("0.004.1","Who","are","members","of","which","terrorist","groups","?"),1386453). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_2'),s("0.004.2","Which","people","lead","terrorist","groups","?"),1386459). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_3'),s("0.004.3","Which","people","lead","which","terrorist","groups","?"),1386465). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_4'),s("0.004.4","What","groups","(","legitmate","or","otherwise",")","do","which","terrorists","lead","?"),1386470). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_5'),s("0.004.5","What","terrorist","groups","do","which","terrorists","lead","?"),1386477). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS4_6'),s("0.004.6","What","non-terrorist","groups","are","led","by","terrorists","?"),1386487). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS5_1'),s("0.005.1","Who","owns","what","types","of","chemical","weapons","?"),1386509). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS5_2'),s("0.005.2","Who","owns","what","individual","chemical","weapons","?"),1386514). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS6_1'),s("0.006.1","Who","owns","which","kinds","of","chemical","warfare","agents","?"),1386522). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS6_2'),s("0.006.2","Who","owns","which","chemical","warfare","agent","samples","?"),1386527). assertion_content_comment(nartR('iCW_TestQueryFn','iCDE_KBCTS7_1'),s("0.007.1","Where","are","chemical","agents","known","to","be","located","?"),1386540). assertion_content_comment(nartR('iCW_TestQueryFn','iCrossoverCTS_DistanceBetweenDamAndHospital_2'),s("What","is","the","distance","between","Seton","Medical","Center","and","Marshall","Ford","Dam","?"),1409771). assertion_content_comment(nartR('iCW_TestQueryFn','iCrossoverCTS_DistanceBetweenDams_2'),s("What","is","the","distance","between","Llano","City","Lake","and","Marshall","Ford","Dam","?"),1409798). assertion_content_comment(nartR('iCW_TestQueryFn','iCTCQueryBuilderCoordinatesOfPlace'),s("What","is","the","latitude","and","longitude","of","The","White","House","?"),1438314). assertion_content_comment(nartR('iCW_TestQueryFn','iCTCQueryBuilderPrecursorToWhat'),s("What","agents","have","phosphorous","trichloride","as","a","precursor","?"),1438023). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_AirportQueryDoesAirportServeCity'),s("Airport","6",":","Does","JFK","airport","service","New","York","City","?"),1384316). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_AirportQueryFindIATACode'),s("Airport","1",":","What","is","the","IATA","code","for","LaGuardia","Airport","?"),1383835). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_AirportQueryNumberOfAirportsInEngland'),s("How","many","airports","are","known","to","service","cities","in","England","?"),1405918). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_AirportQueryWhatCityIsServicedByCode'),s("Airport","4",":","What","cities","are","serviced","by","the","airport","with","the","IATA","code","\"","LGA","\"","?"),1383974). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_AirportQueryWhichCitiesInEnglandHaveAirports'),s("Airport","5",":","Which","cities","in","England","are","serviced","by","airports","?"),1383996). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_01'),s("1",".","What","Biological","Agent","might","be","stored","as","a","brown","powder","?"),1400748). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_02'),s("2",".","What","Biological","Agent","might","be","stored","as","a","white","powder","?"),1400764). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_03'),s("3",".","What","Biological","Agent","might","be","stored","as","a","yellow","powder","?"),1400782). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_04'),s("4",".","What","Chemical","Agent","might","be","stored","as","a","brown","powder","?"),1400798). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_05'),s("5",".","What","Chemical","Agent","might","be","stored","as","a","white","powder","?"),1404736). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_06'),s("6",".","What","Chemical","Agent","might","be","stored","as","a","yellow","powder","?"),1404759). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_07_1'),s("7.1","What","biological","agents","can","be","effectively","dispersed","via","aerosolizing","?"),1405295). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_07_2'),s("7.2","What","chemical","agents","can","be","effectively","dispersed","via","aerosolizing","?"),1405334). 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assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_09_3'),s("9.3","What","is","the","average","incubation","period","for","smallpox","infections","?"),1405412). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_09'),s("9",".","What","is","the","incubation","period","for","infections","caused","by","the","smallpox","virus","?"),1405347). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_10_1'),s("10.1","What","Biological","agents","have","an","average","incubation","period","of","less","than","5","days","?"),1420199). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_10'),s("What","Biological","agents","have","an","incubation","period","of","less","than","5","days","?"),1420254). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_11_1'),s("11.1","What","Biological","agents","have","an","average","incubation","period","of","between","5","and","10","days","?"),1420270). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_11'),s("11",".","What","Biological","agents","have","an","incubation","period","of","between","5","and","10","days","?"),1422096). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_12_1'),s("12",".","What","Biological","agents","have","an","average","incubation","period","of","greater","than","10","days","?"),1420146). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_12'),s("12",".","What","Biological","agents","have","an","incubation","period","of","greater","than","10","days","?"),1420161). 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assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_19'),s("19",".","What","blister","agents","would","cause","what","symptoms","?"),1433805). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_20'),s("20",".","Which","blood","agents","would","cause","symptoms","?"),1401141). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_21'),s("21",".","Which","nerve","agents","would","cause","what","symptoms","?"),1433932). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_22'),s("22",".","What","are","the","classes","of","agents","?"),1386275). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_23'),s("23",".","What","are","the","precursor","agents","to","mustard","gas","?"),1400832). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_24'),s("24",".","What","are","the","health","effects","of","exposure","to","phosgene","oxime","?"),1401152). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_26'),s("26",".","What","is","the","boiling","point","of","Lewisite","?"),1400808). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_27'),s("27",".","What","is","the","flash","point","of","mustard","gas","?"),1400908). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_28'),s("What","is","the","evaporation","rate","of","acetic","acid","?"),1403292). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_29'),s("29",".","What","is","the","volume","of","a","standard","tanker","?"),1401077). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_31'),s("31",".","What","Biological","agent","causes","bubonic","plague","?"),1400862). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_32_1'),s("32.1",".","What","gram","negative","bacteria","cause","diseases","?"),1401357). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_32_2'),s("32.2","What","rod-shaped","bacteria","cause","diseases","?"),1401373). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_32'),s("32",".","What","gram","negative","rod","causes","diseases","?"),1386304). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_34_1'),s("34.1","What","chemical","agents","can","be","used","for","crowd","control","?"),1417716). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_34_2'),s("34.2","Which","chemical","agents","have","been","used","used","to","control","crowds","on","what","occasions","?"),1401417). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_34'),s("34",".","What","chemical","agents","are","used","for","crowd","control","?"),1401400). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_35_1'),s("35.1","Which","agents","have","boiling","points","less","than","or","equal","to","room","temperature",",","and","what","are","those","boiling","points","?"),1401435). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_35'),s("35",".","Which","agents","have","boiling","points","less","than","or","equal","to","room","temperature","?"),1386318). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_37_1'),s("37.1","What","chemical","agents","are","used","to","make","glue","?"),1422916). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_37'),s("37",".","What","chemical","agent","is","used","in","glue","?"),1401459). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_38'),s("38",".","What","are","the","ingredients","of","the","explosive","agent","ANFO","?"),1401467). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_39'),s("39",".","What","household","agents","can","be","used","as","a","ChemBio","weapon","?"),1401478). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_40'),s("40",".","What","are","the","blister","agents","?"),1386341). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_41'),s("What","is","the","antidote","to","Sarin","?"),1411143). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_42'),s("42",".","What","causes","myosis","?"),1386251). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_43'),s("43",".","What","do","the","various","nerve","agents","smell","like","?"),1410888). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_44'),s("44",".","What","chemical","agent","smells","like","burnt","almonds","?"),1401506). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_44'),s("The","query","originally","asked","for","nerve","agents","instead","of","chemical","agents",",","but","as","far","as","we","know",",","no","nerve","agents","have","the","smell","of","burnt","almonds","."),1401505). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_45'),s("45",".","What","are","the","symptoms","of","a","blood","agent","exposure","?"),1401529). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_46'),s("46",".","How","quickly","do","the","symptoms","of","a","blood","agent","appear","?"),1414177). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_54_1'),s("54.1","Define","\"","zoonotic","disease","\""),1401171). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_54'),s("54",".","What","are","the","Zoonotic","Diseases","?"),1400889). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_56'),s("56",".","What","fungi","can","be","used","as","Biological","agents","?"),1401544). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_57_1'),s("57.1","What","toxins","can","be","produced","by","which","fungi","?"),1401813). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_57'),s("57",".","What","toxins","can","be","produced","by","fungi","?"),1401738). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_58'),s("58",".","What","is","the","treatment","for","chlorine","inhalation","?"),1417401). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_59'),s("59",".","What","is","the","treatment","for","ammonia","inhalation","?"),1417447). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_61'),s("61",".","What","is","the","minimum","detectable","level","to","smell","ammonia","?"),1418928). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_62'),s("62",".","What","is","the","short","term","exposure","limit","for","ammonia","?"),1417557). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_63'),s("63",".","What","is","the","permissible","exposure","limit","for","ammonia","?"),1417539). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_64'),s("64",".","What","is","the","recommended","personal","protection","equipment","for","ammonia","inhalation","?"),1417522). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_65'),s("65",".","What","is","immediate","danger","to","life","and","health","(","IDLH",")","?"),1417266). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_66'),s("What","is","the","CAS","registery","number","for","cyanide","?"),1401970). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_79'),s("79",".","What","biological","aerosols","are","odorless","?"),1399936). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_80'),s("80",".","What","biological","aerosols","are","tasteless","?"),1404707). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_82'),s("What","units","can","detect","biochemically","harmful","substances","?"),1435378). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_87'),s("87",".","What","things","are","vulnerable","to","an","attack","using","what","type","of","object","?"),1401900). 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assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_90_1'),s("This","query","is","intended","to","replace","Question","90",",","\"","Where","are","the","major","hospitals","in","DC","?","\"","which","we","don","'","t","have","the","resources","to","answer","effectively","."),1401927). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_90_2'),s("90",".","Where","are","the","major","hospitals","in","DC","?"),1419971). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_90'),s("90",".","Where","are","the","major","hospitals","in","DC","?"),1404901). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_90'),s("My","query","literally","asks","for","hospitals","in","Washington",",","DC","that","have","more","than","500","beds",",","their","street","address","and","the","number","of","beds","they","have","."),1404902). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_95_1'),s("95.1","What","types","of","physical","parts","do","dirty","bombs","have","?"),1401877). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_95'),s("95",".","What","material","is","required","to","make","a","dirty","bomb","?"),1401854). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_96_1'),s("96.1","What","viral","agents","can","cause","Gastroenteritis","?"),1401819). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_96'),s("96",".","What","bacterial","agents","can","cause","gastroenteritis","?"),1401759). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_97_A'),s("What","viral","agents","have","no","known","vaccine","?"),1440911). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_97_B'),s("What","bacterial","agents","have","no","known","vaccine","?"),1440894). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNE_4_30_2003_Test_97'),s("97",".","What","bacterial","or","viral","agents","have","no","known","vaccine","?"),1401836). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEIncubationPeriodQuery'),s("This","template","may","appear","to","be","a","duplicate","of","a","similar","CBRNE","template","for","incubation","periods",",","but","this","one","is","important","for","testing","purposes",".","We","are","using","it","to","test","#$","formulaTemplateFollowUp","in","the","FET","."),1432328). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEIncubationPeriodQuery'),s("What","infections","have","an","average","incubation","period","of","greater","than","3","days","?"),1432321). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS10'),s("0.010","|","Which","substances","have","IDHL","concentrations","below","50","ppm","?"),1361303). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS11'),s("0.011","|","Which","substances","have","IDLH","concentrations","above","50","ppm","?"),1361313). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS12'),s("0.012","At","what","temperature","does","ammonium","nitrate","decompose","?"),1384151). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS13'),s("0.013","Which","chemicals","decompose","at","temperatures","above","800","degrees","Celsius","?"),1384163). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS14'),s("0.014","Identify","all","known","explosive","agents","."),1398294). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS15'),s("What","are","the","symptoms","of","nerve","agent","exposure","?"),1420132). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS1'),s("0.001","What","ailments","are","caused","by","inhaling","cyclosarin","gas","?"),1348284). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS2'),s("0.002","Which","is","more","volatile",",","Sarin","or","VX","?"),1419712). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS3'),s("0.003","Identify","non-immediate","precursors","to","nerve","agents","."),1349106). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS4'),s("0.004","Identify","all","known","nerve","agents","."),1349115). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS5'),s("0.005","What","kinds","of","nerve","agent","weapons","do","you","know","about","?"),1352750). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS6'),s("0.006","Is","it","true","that","no","G-Series","nerve","agent","is","more","volatile","than","Sarin","?"),1352795). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS7'),s("0.007","What","is","the","state","of","matter","of","HN3","at","room","temperature","?"),1355136). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS8'),s("0.008","Which","is","more","toxic","to","inhale",",","VX","or","Phosgene","Oxime","?"),1418476). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CBRNEKBCTS9'),s("0.009","Suppose","a","sample","of","air","has","a","3000","PPM","concentration","of","acetone","--","is","that","air","toxic","to","breathe","?"),1361240). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CDEKBCTS3'),s("0.003","Where","have","known","terrorists","been","known","to","be","?"),1386432). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CDEKBCTS4'),s("0.004","Who","is","affiliated","with","which","terrorist","groups","?"),1386446). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CDEKBCTS5'),s("0.005","Who","owns","chemical","weapons","?"),1386493). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CDEKBCTS6'),s("0.006","Who","owns","chemical","warfare","agents","?"),1386501). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CDEKBCTS7'),s("0.007","Where","are","known","chemical","weapons","?"),1386535). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ChemQueryHeatOfVaporization'),s("0.016","What","is","the","heat","of","vaporization","for","acetic","acid","?"),1386122). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CitiesWithMoreThan100000GenericCattle'),s("Identify","cities","with","more","than","one","hundred","thousand","cattle","."),1409789). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ColoredAnimalsTestQueryBadBlueEmus'),s("Make","sure","that","if","one","lexical","meaning","is","explicitly","chosen",",","and","all","but","one","phrasal","meaning","that","uses","that","lexical","meaning","are","ruled","out",",","that","a","phrasal","meaning","that","uses","the","other","lexical","meaning","will","*","not","*","be","chosen","."),1411607). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ColoredAnimalsTestQueryBlueEmus'),s("If","all","but","one","meaning","for","each","lexical","node","is","eliminated",",","the","phrasal","meaning","must","be","the","combination","of","the","remaining","meanings","."),1410469). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ColoredAnimalsTestQueryRedEmus'),s("Make","sure","that","if","one","lexical","meaning","is","explicitly","chosen",",","and","all","but","one","phrasal","meaning","that","uses","that","lexical","meaning","are","ruled","out",",","that","the","remaining","phrasal","meaning","will","be","chosen","."),1410456). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CrossoverCTSATFInstallationsInLA'),s("What","ATF","installations","have","their","headquarters","in","Los","Angeles","?"),1358477). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CrossoverCTSNumberOfCowsInCity'),s("Approximately","how","many","cows","are","found","in","Austin",",","Minnesota","?"),1358551). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CSTDoesCompletelyEnumerableCollectionWorkForSmallIntegerSequences'),s("Cyc",",","please","tell","me","what","all","the","integers","are","from","1","to","4","."),1417209). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CSTWaterIsWet'),s("Is","water","wet","?"),1469965). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCCommonPrecursors'),s("What","agent","is","common","to","these","precursors",":","Dimethyl","methylphosphonate",",","Hydrogen","fluoride",",","Isopropyl","alcohol"),1419735). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCDoFiltrationMasksProtectAgainstGaseousSarin'),s("Are","filtration","masks","effective","against","sarin","gas","?"),1428777). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCFeaturesBetweenLatLongNumbersCP1'),s("What","are","the","known","features","between","31.0634","and","32.034","latitiude","and","-96.9392","and","-97.9392","longitude","?"),1440351). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCFedAgenciesInPhillyAndAddresses'),s("What","federal","agencies","are","located","in","Philadelphia","and","what","are","their","addresses","?"),1420062). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHasHusseinSentUraniumToOtherCountries'),s("Has","Hussein","sent","uranium","to","other","countries","?"),1420026). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHasHusseinSentUraniumToOtherCountries'),s("Unable","to","get","bindings","because","the","(","Davidsonian",")","predicates","used","in","the","query","are","not","the","same","as","those","used","to","slurp","in","data","from","the","CDE","database",".","See","#$","BBNTagTranslationConstants",".","(","Note","from","Glen","Meyer","on","7/17/2003",")"),1420027). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowCanCesium137BeDetected'),s("How","can","Cesium137","be","detected","?"),1434808). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowCanCobalt60BeDetected'),s("How","can","Cobalt60","be","detected","?"),1434734). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowCanDepletedUraniumBeDetected'),s("How","can","depleted","Uranium","be","detected","?"),1434914). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowCanUranium238BeDetected'),s("How","can","Uranium238","be","detected","?"),1434933). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowCanUraniumBeDetected'),s("How","can","Uranium","be","detected","?"),1434858). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowLongWillAnthraxContaminateAnArea'),s("How","long","will","an","area","be","contaminated","with","anthrax","?"),1440147). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCHowLongWillSarinContaminateAnArea'),s("How","long","will","the","area","be","contaminated","?"),1438286). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCIraqHasLinksToTerrorists'),s("Does","Iraq","have","any","links","to","terrorists","?"),1440389). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCIraqSupportingAttacksInIsrael'),s("Has","Iraq","supported","terrorist","attacks","in","Israel","?"),1433686). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCIraqSupportsTerrorists'),s("Does","Iraq","support","terrorists","?"),1433851). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCIraqSupportsTerrorists'),s("In","order","for","this","query","to","work",",","one","must","first","evaluate","these","settings",":","(","csetq","*","completeness-handling-enabled","?","*","t",")","and","(","csetq","*","removal-lookup-considered-incomplete","?","*","t",")","I","believe","that","this","will","become","unnecessary","soon",".","Also",",","Chip","is","working","on","improving","the","speed","for","this","query",".","(","Note","from","Amy","Drummond","on","08/01/2003",")"),1433850). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCIsChemicalProtectiveAttireEffectiveAgainstSarin'),s("Is","chemical","protective","attire","effective","against","sarin","?"),1428795). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCLatLongForCrawfordTXCP1'),s("What","are","the","latitude","and","longitude","values","for","Crawford",",","Texas","?"),1440337). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderAddressOfCycorpHeadquarters'),s("What","is","the","address","of","Cycorp","'","s","headquarters","?"),1440311). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderBiologicalToxins'),s("What","are","the","biological","toxins","?"),1438946). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderCBRNEAgent'),s("What","are","the","CBRNE","agents","?"),1439965). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderColorOfAgent'),s("What","agents","are","yellow","?"),1437856). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderContactInfo'),s("What","is","the","address","of","Cycorp","?"),1437260). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderInstancesOfHospital'),s("What","are","the","various","hospitals","?"),1437195). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderLethalityOfAgent'),s("What","is","the","lethality","of","Sarin","for","various","organisms","?"),1437999). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderLocationOfWhiteHouse'),s("Where","is","the","White","House","located","?"),1437942). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderMilitaryUnitsInPlaceCapableOfSomething'),s("What","military","units","in","Texas","are","capable","of","detecting","radiological","weapons","?"),1438430). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderMilitaryUnitsInPlace'),s("What","military","units","are","in","Texas","?"),1438407). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderNumberOfObjectsInLocation'),s("How","many","television","stations","are","located","in","Austria","?"),1437233). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderObjectFoundInLocation'),s("Where","is","the","space","needle","located","?"),1437216). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderOdorOfAgent'),s("What","agents","are","odorless","?"),1437969). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderPlaceAtCoordinates'),s("What","is","found","at","the","coordinates","latitude","38.895","degrees",",","longitude","-77.03667","degrees","?"),1438367). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderPrecursorsToAgent'),s("What","are","the","precursors","to","Sarin","?"),1438060). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderPresentInRegion'),s("What","organizations","have","a","presence","in","Iraq","?"),1437724). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderProtectiveAttire'),s("What","protective","attire","is","appropriate","for","a","responder","to","a","Sarin","attack","?"),1438083). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderSponsors'),s("What","does","Iraq","sponsor","?"),1437755). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderSymptomsOfBiologicalAgent'),s("What","are","the","symptoms","of","infections","caused","by","anthrax","?"),1438142). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderSymptomsOfChemicalAgent'),s("What","are","the","symptoms","of","Sarin","poisoning","?"),1438114). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderTransparencyOfAgent'),s("What","agents","are","transparent","?"),1437887). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderTreatmentForAgent'),s("What","are","the","treatments","for","Sarin","poisonings","?"),1437992). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderTypesOfProtectiveAttire'),s("What","are","the","types","of","protective","attire","?"),1437325). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatBiologicalAgentsCauseVomiting'),s("What","biological","agents","cause","vomiting","?"),1439326). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatChemicalAgentsCausePulmonaryEdema'),s("What","chemical","agents","cause","pulmonary","edema","?"),1439320). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatIsLocatedInAustin'),s("What","is","in","Austin",",","Texas","?"),1437853). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatIsPlutonium241'),s("What","is","Plutonium","241","?"),1438551). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatIsPlutonium241UsedFor'),s("What","is","Plutonium","241","used","for","?"),1438571). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatLethalWeaponUsesPlutonium241'),s("What","lethal","weapons","could","be","made","from","Plutonium","241","?"),1438710). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCQueryBuilderWhatsInterestingAboutPlace'),s("What","'","s","interesting","about","Austin","Texas","?"),1438389). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCRelationBetweenAberdeenAnnistonAndBlueGrass'),s("What","is","the","relationship","between","the","Aberdeen","Proving","Grounds",",","Anniston","Army","Depot","and","the","Blue","Grass","Army","Depot","?"),1438337). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCSponsoredTerroristsInIraq'),s("What","terrorist","groups","located","in","Iraq","does","Iraq","sponsor","?"),1434152). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCSummarizeLethalityOfAnhydrousAmmoniaForHumans'),s("What","is","known","about","the","lethality","of","anhydrous","ammonia","for","humans","?"),1431512). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCSummarizeLethalityOfSodiumCyanideForHumans'),s("Summarize","what","'","s","known","about","the","lethality","of","sodium","cyanide","to","humans","."),1429850). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCTreatmentForSarinPoisoningOLD'),s("What","are","the","treatments","for","sarin","poisoning","?"),1429740). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCTreatmentForSarin'),s("What","is","the","treatment","for","Sarin","?"),1434194). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCTreatmentSummaryForAnthrax'),s("What","is","the","treatment","for","an","exposure","to","anthrax","bacterium","?"),1441034). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWeaponFromRadiologicalMaterialQueryTemplate'),s("What","lethal","device","can","be","made","from","any","type","of","fissionable","material","?"),1443654). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWeaponWithAnyTypeOfCobalt60Cesium137Uranium'),s("What","lethal","device","can","be","made","from","any","type","of","uranium",",","cobalt","60",",","or","cesium","137","?"),1439721). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWeaponWithCobalt60Cesium137UraniumAlt'),s("What","lethal","device","could","be","made","from","Cobalt","60",",","Cesium","137",",","or","Uranium","?"),1434899). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWeaponWithCobalt60Cesium137Uranium'),s("What","kind","of","lethal","device","can","be","made","with","some","type","of","Cobalt60",",","Cesium137",",","or","Uranium","?"),1437800). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheLethalitiesOfTheVariousFormsOfAnthrax'),s("What","are","the","lethalities","of","the","various","forms","of","anthrax","?"),1431575). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheSymptomsOfAnthraxInfection'),s("What","are","the","symptoms","of","anthrax","infection","?"),1431395). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheSymptomsOfTheVariousFormsOfAnthraxInfection'),s("What","are","the","symptoms","of","the","various","forms","of","anthrax","infection","?"),1431432). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheTreatmentsForExposureToVariousAgentsOLD'),s("What","are","the","treatments","for","exposure","to","various","agents","?"),1432133). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheTreatmentsForPoisoningByVariousAgentsOLD'),s("What","are","the","treatments","for","poisonings","by","various","agents","?"),1432149). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatAreTheTreatmentsForVariousAgents'),s("What","are","the","treatments","for","various","biochemical","agents","?"),1434223). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatChemicalsHavePrecursor'),s("What","is","sodium","cyanide","a","precursor","to","?"),1419871). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsCesium137'),s("What","is","cesium","137","?"),1439727). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsCesium137UsedFor'),s("What","is","Cesium","137","used","for","?"),1434533). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsCobalt60'),s("What","is","cobalt","60","?"),1438504). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsCobalt60UsedFor'),s("What","is","Cobalt-60","used","for","?"),1438676). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsInterestingAboutCrawfordTX'),s("What","'","s","interesting","about","Crawford",",","TX","?"),1439292). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheIncubationPeriodForAnthrax'),s("What","is","the","incubation","period","for","anthrax","?"),1434314). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfAnhydrousAmmonia'),s("What","is","the","lethality","of","anhydrous","ammonia","?"),1431491). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfAnthrax'),s("Summarize","known","lethality","information","about","anthrax","."),1437438). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfNaCN'),s("What","is","the","lethality","of","sodium","cyanide","?"),1422863). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfNH3'),s("What","is","the","lethality","of","anhydrous","ammonia","?"),1422848). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfSodiumCyanide'),s("What","is","the","lethality","of","sodium","cyanide","?"),1429872). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsTheLethalityOfTypesOfAnthrax'),s("What","is","the","lethality","of","anthrax","?"),1431756). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatIsUraniumUsedFor'),s("What","is","uranium","used","for","?"),1439599). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatProtectiveGearShouldBeWornForAnthrax'),s("What","type","of","protective","gear","should","the","responders","wear","to","a","release","of","anthrax","?"),1428953). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatProtectiveGearShouldRespondersWearToASarinRelease'),s("What","type","of","protective","gear","should","the","responders","wear","to","a","release","of","sarin","?"),1428926). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhatSymptomsAreAssociatedWithExposureToAnthrax'),s("What","symptoms","are","associated","with","exposure","to","anthrax","?"),1437165). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhichColorlessOdorlessChemicalAgentsCauseSeizuresAndWhichOtherSymptoms'),s("Which","colorless",",","odorless","chemical","agents","cause","seizures","in","addition","to","which","other","symptoms","?"),1433950). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_CTCWhichColorlessOdorlessChemicalAgentsCauseWhichSymptoms'),s("Which","colorless",",","odorless","chemical","agents","cause","which","symptoms","?"),1433306). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_DBOnlyCTSDamTypeSubstringQuery'),s("Find","all","dams","that","are","rockfill","dams","for","irrigation","and","water","supply",",","have","uncontrolled","spillage",",","a","significant","downstream","hazard","potential","and","are","not","federally","owner","or","regulated","."),1361250). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_EIICitiesInCAATFInstallations'),s("Which","Bureau","of","Alcohol",",","Tobacco","and","Firearm","installations","operate","in","California","?"),1355360). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_EIICrossoverCTS1'),s("What","are","desirable","targets","for","terrorist","attacks","?"),1437775). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_EIIFedInstallationsInLA'),s("Which","federal","agencies","have","installations","in","Los","Angeles","?"),1411457). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_EIIGreaterThanHospitalBedQuery'),s("What","hospitals","|","have","more","than","1500","hospital","beds","?"),1354162). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_EIITotalHospitalBedQuery'),s("What","is","the","total","|","number","of","hospital","beds","in","Los","Angeles","?"),1354155). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ExplosivesQueryChemicalPrecursorsOfAmmoniumNitrate'),s("What","are","the","chemical","precursors","to","ammonium","nitrate","?"),1399719). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ExplosivesQueryExplosiveVelocityOfNitroglycerine'),s("What","is","the","explosive","velocity","of","nitroglycerine","?"),1399698). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ExplosivesQueryNitricAcidsIsChemicalPrecursorToWhichExplosives'),s("To","which","explosives","is","nitric","acid","a","chemical","precursor","?"),1399729). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_ForceElementGISQueryBuilder'),s("What","are","all","the","force","elements","known","to","this","GIS","?"),1485967). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_Guide125SubstancesEIIQuery'),s("Which","substances","are","assigned","to","the","NAERG","number","125","?"),1403270). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA11a'),s("DA11a",":","The","acid","ionization","constant","Ka","for","propanoic","acid",",","C2H5COOH","is","1.3E-5",".","Calculate","the","hydrogen","ion","concentration",",","[","H","+","]",",","in","a","0.35-molar","solution","of","propanoic","acid","."),1861103). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA11b'),s("DA11b",":","The","acid","ionization","constant","for","propanoic","acid","is","1.3E-5",".","Consider","a","0.35-molar","solution","of","propanoic","acid",".","|","Calculate","the","percentage","of","propanoic","acid","molecules","that","are","ionized","in","this","solution","."),1860873). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA11d'),s("DA11d",":","The","acid","ionization","constant","Ka","for","propanoic","acid",",","C2H5COOH",",","is","1.3E-5",".","In","a","100","ml","sample","of","a","different","buffer","solution",",","the","propanoic","acid","is","0.35-molar","and","the","sodium","propanoate","concentration","is","0.50-molar",".","To","this","buffer","solution",",","solid","NaOH","is","added",".","Would","the","pH","increase","or","decrease","?"),1860513). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA12a'),s("DA12a",":","The","ionization","constant","for","dimethylamine",",","(","CH3",")","2NH",",","is","5.4e-4",".","Dimethyl","amine","is","a","substituted","ammonia","compound",".","Calculate","the","pH","and","pOH","of","a","0.125","M","solution","of","dimethylamine","."),1860986). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA12c'),s("DA12c",":","The","ionization","constant","for","dimethylamine",",","(","CH3",")","2NH",",","is","5.4e-4",".","Dimethyl","amine","is","a","substituted","ammonium","compound",".","Determine","the","pH","of","a","solution","made","by","adding","0.0250","moles","of","solid","dimethylammonium","nitrate","to","250.0","mL","of","a","0.350","M","solution","of","dimethylamine",".","Assume","no","volume","change","occurs","."),1860427). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA13a'),s("DA13a",":","Boric","acid","is","a","very","weak","acid","with","a","Ka","=","5.8E-10",".","Boric","acid","is","a","colorless","compound",".","Calculate","the","pH","of","a","0.0010M","solution","of","boric","acid","."),1860751). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA13b'),s("DA13b",":","Boric","acid","is","a","very","weak","acid","with","a","Ka","=","5.8E-10",".","Boric","acid","is","a","colorless","compound",".","What","is","the","pH","of","a","buffer","solution","produced","by","mixing","0.010","moles","of","sodium","borate","with","100.0ml","of","0.0150","moles","of","boric","acid","?","Assume","that","no","volume","change","occurred","."),1860774). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA14c'),s("DA14c",":","The","acid","dissociation","constant","for","benzoic","acid","(","C6H5COOH",")","is","6.3E-5",".","What","is","the","pH","of","a","1.0","M","solution","of","benzoic","acid","?"),1860357). assertion_content_comment(nartR('iCW_TestQueryFn','iCW_HaloPilotChallengeDA15aii'),s("DA15aii",":","The","Kw","value","for","water","is","dependent","on","temperature",".","At","0C","the","value","is","1.2E-15",".","Nitrous","acid","Ka","=","4.5E-4",".","Calculate","the","pOH","of","a","0.050M","solution","of","nitrous","acid",".","(","Ka","=","4.5E-4",")","at","0C",".","Assume","that","the","acid","ionization","constant","does","not","change","with","temperature","."),1860801). 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assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzInsect'),s("Insect","genetics",":","a","#$","FieldOfStudy","."),3011413). assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzMonocotSubclass'),s("Monocot","genetics",":","a","#$","FieldOfStudy","."),3011535). assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzMouseRodent'),s("Mouse","genetics",":","a","#$","FieldOfStudy","."),3011539). assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzNematode'),s("Nematode","genetics",":","a","#$","FieldOfStudy","."),3011545). assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzParasiticOrganism'),s("Parasite","genetics",":","a","#$","FieldOfStudy","."),3011600). assertion_content_comment(nartR('iFieldAppliedToFn','iGenetics','tClazzProkaryoticCell'),s("Prokaryote","genetics",":","a","#$","FieldOfStudy","."),3011649). 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assertion_content_comment(nartR('iFieldAppliedToFn','iHistoryFieldOfStudy','tObjectHelicopter'),s("Helicopter","history",":","a","#$","FieldOfStudy","."),3011351). assertion_content_comment(nartR('iFieldAppliedToFn','iHistoryFieldOfStudy','ttSocialScienceType'),s("History","of","the","social","sciences",":","a","#$","FieldOfStudy","."),3011379). assertion_content_comment(nartR('iFieldAppliedToFn','iMicrobiology','iMedicineFieldOfStudy'),s("Medical","microbiology",":","a","#$","FieldOfStudy","."),3011476). assertion_content_comment(nartR('iFieldAppliedToFn','iMicrobiology','tEcosystem'),s("Environmental","microbiology",":","a","#$","FieldOfStudy","."),3011227). assertion_content_comment(nartR('iFieldAppliedToFn','iMicrobiology','tFood'),s("Food","microbiology",":","a","#$","FieldOfStudy","."),3011264). assertion_content_comment(nartR('iFieldAppliedToFn','iMicrobiology','tPlaceLikeGround'),s("Soil","microbiology",":","a","#$","FieldOfStudy","."),3011738). 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assertion_content_comment(nartR('iFieldAppliedToFn','iPsychology','mobHumanChild'),s("Child","psychology",":","a","#$","FieldOfStudy","."),3011115). assertion_content_comment(nartR('iFieldAppliedToFn','iPsychology','tGroupedEducationalOrganization'),s("Educational","organization","psychology",":","a","#$","FieldOfStudy","."),3011217). assertion_content_comment(nartR('iFieldAppliedToFn','iPsychology','tTypeOfPersonTypeByGender'),s("Gender","psychology",":","a","#$","FieldOfStudy","."),3011293). assertion_content_comment(nartR('iFieldAppliedToFn','iPsychology','vtColor'),s("Color","psychology",":","a","#$","FieldOfStudy","."),3011140). assertion_content_comment(nartR('iFieldAppliedToFn','iRelativityTheory','iCosmology'),s("Cosmology","relativity","theory",":","a","#$","FieldOfStudy","."),3011154). assertion_content_comment(nartR('iFieldAppliedToFn','iStatistics','tEconomicSystem'),s("Economic","system","statistics",":","a","#$","FieldOfStudy","."),3011214). assertion_content_comment(nartR('iFieldAppliedToFn','iStructuralEngineering','tPlaceLikeBridge'),s("Bridge","structural","engineering",":","a","#$","FieldOfStudy","."),3011072). assertion_content_comment(nartR('iFieldAppliedToFn','iTheology','iShiiteIslam'),s("Shiite","Islam","theology",":","a","#$","FieldOfStudy","."),3011721). assertion_content_comment(nartR('iFieldAppliedToFn',nartR('iFieldConcerningFn','iIslam'),'cwLaw'),s("Islamic","law",":","a","#$","FieldOfStudy","."),3011424). assertion_content_comment(nartR('iFieldConcerningFn','actEducation'),s("Education-related","field",":","a","#$","FieldOfStudy","."),3011216). assertion_content_comment(nartR('iFieldConcerningFn','iIslam'),s("Islamic","studies",":","a","#$","FieldOfStudy","."),3011425). assertion_content_comment(nartR('iFieldConcerningFn','tJournalismSystem'),s("Journalism",":","a","#$","FieldOfStudy","."),3011429). 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assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxAnalyst_TaskingPS',"Assignment_Active"),s("An","indicator","that","this","assignment","is","active","for","this","analyst",".","Choices","are","yes","and","no",".","Yes","means","the","task","may","appear","in","the","Analyst","list","of","tasks","that","he","can","select","from",".","No","means","it","does","not","appear",".","Whether","the","tasking","is","visible","to","the","Analyst","is","controlled","by","both","the","Assignment_Active","field","and","the","Tasking_Active","fields",".","To","appear","in","the","analyst","'","s","list","both","the","Assignment_Active","and","the","Tasking_Active","fields","must","be","'","yes","'"),1789352). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxReceive_MethodPS',"Order_Display"),s("A","value","to","control","the","order","of","the","records","when","they","are","displayed","in","the","pull-down","list","within","the","Control","Panel","."),1779591). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxReceive_MethodPS',"Receive_Method_Active"),s("An","indicator","of","whether","this","receive","method","is","currently","active",".","\"","Yes","\"","means","it","is","currently","active","and","thus","appears","in","the","pull-down","list","when","a","record","is","recorded",".","\"","No","\"","means","it","is","not","visible","when","recording","."),1779593). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxReceive_MethodPS',"Receive_Method_ID"),s("A","globally","unique","identifier","for","the","Receive_Method","record","."),1779594). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxReceive_MethodPS',"Receive_Method"),s("The","method","by","which","this","tasking","was","received","from","the","client",".","Choices","include","e-mail",",","telephone","."),1779592). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Due_Date"),s("The","date","the","analysis","of","this","tasking","is","to","be","completed","."),1780530). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Info_Cutoff_Date"),s("The","date","after","which","new","information","will","not","be","included","in","the","requested","analysis","."),1780529). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Received_Date"),s("The","date","this","tasking","was","received","."),1780527). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Receive_Method_ID"),s("A","globally","unique","identifier","for","the","Receive_Method","record","."),1780528). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Task_Domain_ID"),s("A","globally","unique","identifier","for","this","Task_Domain","record","."),1780531). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Tasking_Active"),s("An","indication","of","whether","the","tasking","is","active","or","not",".","A","value","of","\"","Yes","\"","means","the","tasking","is","active",".","A","value","of","\"","No","\"","means","the","tasking","is","not","active",".","Whether","the","tasking","is","visible","to","the","Analyst","is","controlled","by","both","the","Assignment_Active","field","and","the","Tasking_Active","fields",".","To","appear","in","the","analyst","'","s","list","both","the","Assignment_Active","and","the","Tasking_Active","fields","must","be","\"","yes","\""),1780533). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Tasking_Description"),s("A","description","of","the","task",".","It","should","include","the","task","'","s","complexity",",","importance","and","urgency","."),1780534). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Tasking_ID"),s("A","globally","unique","identifier","for","the","Tasking","record","."),1780535). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Tasking_Name"),s("A","short","but","identifiable","name","for","this","task",".","The","Tasking_Name","is","the","label","used","in","the","Glass","Box","Control","Panel","or","Review","Tool","to","select","the","task","of","interest","."),1780536). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"Task_Type_ID"),s("A","globally","unique","identifier","for","the","Task_Type","record","."),1780532). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"T_Record_Close_Datetime"),s("The","date","and","time","before","which","the","description","of","the","tasking","as","recorded","in","this","record","is","applicable","."),1780526). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTasking_HistoryPS',"T_Record_Open_Datetime"),s("The","earliest","date","and","time","that","the","description","of","the","tasking","as","recorded","in","this","record","is","applicable",".","That","is",",","at","or","after","this","datetime",",","this","record","describes","the","Tasking","."),1780525). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Due_Date"),s("The","date","the","analysis","of","this","tasking","is","to","be","completed","."),1779496). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Info_Cutoff_Date"),s("The","date","after","which","new","information","will","not","be","included","in","the","requested","analysis","."),1779497). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Received_Date"),s("The","date","this","tasking","was","received","."),1779499). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Receive_Method_ID"),s("A","globally","unique","identifier","for","the","Receive_Method","record","."),1779498). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Task_Domain_ID"),s("A","globally","unique","identifier","for","this","Task_Domain","record","."),1779500). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Tasking_Active"),s("An","indication","of","whether","the","tasking","is","active","or","not",".","A","value","of","\"","Yes","\"","means","the","tasking","is","active",".","A","value","of","\"","No","\"","means","the","tasking","is","not","active",".","Whether","the","tasking","is","visible","to","the","Analyst","is","controlled","by","both","the","Assignment_Active","field","and","the","Tasking_Active","fields",".","To","appear","in","the","analyst","'","s","list","both","the","Assignment_Active","and","the","Tasking_Active","fields","must","be","\"","yes","\""),1779502). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Tasking_Description"),s("A","description","of","the","task",".","It","should","include","the","task","'","s","complexity",",","importance","and","urgency","."),1779503). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Tasking_ID"),s("A","globally","unique","identifier","for","the","Tasking","record","."),1779504). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Tasking_Name"),s("A","short","but","identifiable","name","for","this","task",".","The","Tasking_Name","is","the","label","used","in","the","Glass","Box","Control","Panel","or","Review","Tool","to","select","the","task","of","interest","."),1779505). assertion_content_comment(nartR('iPhysicalFieldFn','iGlassBoxTaskingPS',"Task_Type_ID"),s("A","globally","unique","identifier","for","the","Task_Type","record","."),1779501). assertion_content_comment(nartR('iRLModuleTestCaseFn','iQuantifierOptimizer_3_RLModule',6),s("*","*","NEGATIVE","test",":","output","should","be","the","same","as","input","."),879071). assertion_content_comment(nartR('iSubLSymbolEntityFn','tCycDynamicVariable',uU('uSubLQuoteFn','CYC:*RECURSIVE-QUERIES-IN-CURRENTLY-ACTIVE-PROBLEM-STORE?*')),s("When","#$","True",",","recursive","queries","are","performed","in","the","currently","active","problem","store","."),3666789). assertion_content_comment(nartR('iSubLSymbolEntityFn','tCycDynamicVariable',uU('uSubLQuoteFn','CYC:*STRONGLY-PREFER-CONJUNCTIVE-REMOVAL-MODULES?*')),s("When","#$","True",",","the","#$","CycInferenceEngine","will","strongly","prefer","to","use","conjunctive","removal","modules","over","single-literal","removal","modules","to","find","proofs","for","multi-literal","inference","problems","."),3666788). assertion_content_comment(nartR('iTheFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeThumb')),s("#$","The","left","#$","Thumb"),328271). assertion_content_comment(nartR('iTheFn',nartR('tColOfRightObjectOfPairFn','tPartTypeThumb')),s("#$","The","right","#$","Thumb"),328270). assertion_content_comment(nartR('iTheFn','tClazzMammal'),s("The","mammal",":","a","#$","Mammal","."),3012012). assertion_content_comment(nartR('iTheFn','tEmbryo'),s("The","embryo",":","an","#$","Embryo","."),3011814). assertion_content_comment(nartR('iTheFn','tNaturalLanguage'),s("The","natural","language",":","a","#$","NaturalLanguage","."),3012018). assertion_content_comment(nartR('iTheFn','tObjectAutomobile'),s("The","car",":","an","#$","Automobile","."),3011797). assertion_content_comment(nartR('iTheFn','tObjectInnerTube'),s("The","inner","tube",":","an","#$","InnerTube","."),3011827). assertion_content_comment(nartR('iTheFn','tObjectTaxiCab'),s("The","taxi",":","a","#$","TaxiCab","."),3012053). assertion_content_comment(nartR('iTheFn','tPartTypeAbdominalAorta'),s("The","abdominal","aorta",":","an","#$","AbdominalAorta","."),3011784). assertion_content_comment(nartR('iTheFn','tPartTypeAbdominalCavity'),s("The","abdominal","cavity",":","an","#$","AbdominalCavity","."),3011785). assertion_content_comment(nartR('iTheFn','tPartTypeAlimentaryCanal'),s("The","alimentary","canal",":","an","#$","AlimentaryCanal","."),3011786). assertion_content_comment(nartR('iTheFn','tPartTypeAmnioticSac'),s("The","amniotic","sac",":","an","#$","AmnioticSac","."),3011787). assertion_content_comment(nartR('iTheFn','tPartTypeAnus'),s("The","anus",":","an","#$","Anus","."),3011788). assertion_content_comment(nartR('iTheFn','tPartTypeAorta'),s("The","aorta",":","an","#$","Aorta","."),3011789). assertion_content_comment(nartR('iTheFn','tPartTypeAorticValve'),s("The","aortic","valve",":","an","#$","AorticValve","."),3011790). assertion_content_comment(nartR('iTheFn','tPartTypeAuditorySystem'),s("The","auditory","system",":","an","#$","AuditorySystem","."),3011791). assertion_content_comment(nartR('iTheFn','tPartTypeBladderUrinary'),s("The","urinary","bladder",":","a","#$","Bladder-Urinary","."),3012065). assertion_content_comment(nartR('iTheFn','tPartTypeBrain'),s("The","brain",":","a","#$","Brain","."),3011795). assertion_content_comment(nartR('iTheFn','tPartTypeButtocks'),s("The","rear","end",":","a","#$","Buttocks","."),3012035). assertion_content_comment(nartR('iTheFn','tPartTypeCecum'),s("The","caecum",":","a","#$","Cecum","."),3011796). assertion_content_comment(nartR('iTheFn','tPartTypeCentralNervousSystem'),s("The","central","nervous","system",":","a","#$","CentralNervousSystem","."),3011798). assertion_content_comment(nartR('iTheFn','tPartTypeCerebellum'),s("The","cerebellum",":","a","#$","Cerebellum","."),3011799). assertion_content_comment(nartR('iTheFn','tPartTypeCerebrum'),s("The","cerebrum",":","a","#$","Cerebrum","."),3011800). assertion_content_comment(nartR('iTheFn','tPartTypeCervicalVertebrae'),s("The","cervical","spine",":","a","#$","CervicalVertebrae","."),3011801). assertion_content_comment(nartR('iTheFn','tPartTypeChestBodyPart'),s("The","chest",":","a","#$","Chest-BodyPart","."),3011802). assertion_content_comment(nartR('iTheFn','tPartTypeChin'),s("The","chin",":","a","#$","Chin","."),3011803). assertion_content_comment(nartR('iTheFn','tPartTypeCirculatorySystem'),s("The","circulatory","system",":","a","#$","CirculatorySystem","."),3011804). assertion_content_comment(nartR('iTheFn','tPartTypeCoccyx'),s("The","tail","bone",":","a","#$","Coccyx","."),3012052). assertion_content_comment(nartR('iTheFn','tPartTypeColonBodyPart'),s("The","colon",":","a","#$","Colon-BodyPart","."),3011805). assertion_content_comment(nartR('iTheFn','tPartTypeCommonBileDuct'),s("The","bile","duct",":","a","#$","CommonBileDuct","."),3011793). assertion_content_comment(nartR('iTheFn','tPartTypeCorpusCallosum'),s("The","corpus","callosum",":","a","#$","CorpusCallosum","."),3011807). assertion_content_comment(nartR('iTheFn','tPartTypeCorpusSpongiosum'),s("The","corpus","spongiosum",":","a","#$","CorpusSpongiosum","."),3011808). assertion_content_comment(nartR('iTheFn','tPartTypeDiaphragmBodyPart'),s("The","diaphragm",":","a","#$","Diaphragm-BodyPart","."),3011809). assertion_content_comment(nartR('iTheFn','tPartTypeDiencephalon'),s("The","diencephalon",":","a","#$","Diencephalon","."),3011810). assertion_content_comment(nartR('iTheFn','tPartTypeDigestiveSystem'),s("The","digestive","tract",":","a","#$","DigestiveSystem","."),3011811). assertion_content_comment(nartR('iTheFn','tPartTypeDuodenum'),s("The","duodenum",":","a","#$","Duodenum","."),3011812). assertion_content_comment(nartR('iTheFn','tPartTypeDuraMater'),s("The","dura","mater",":","a","#$","DuraMater","."),3011813). assertion_content_comment(nartR('iTheFn','tPartTypeEpiglottis'),s("The","epiglottis",":","an","#$","Epiglottis","."),3011815). assertion_content_comment(nartR('iTheFn','tPartTypeEsophagus'),s("The","esophagus",":","an","#$","Esophagus","."),3011816). assertion_content_comment(nartR('iTheFn','tPartTypeEthmoid'),s("The","ethmoid",":","an","#$","Ethmoid","."),3011817). assertion_content_comment(nartR('iTheFn','tPartTypeExternalNose'),s("The","external","nose",":","an","#$","ExternalNose","."),3011818). assertion_content_comment(nartR('iTheFn','tPartTypeFetus'),s("The","fetus",":","a","#$","Fetus","."),3011819). assertion_content_comment(nartR('iTheFn','tPartTypeForeskin'),s("The","foreskin",":","a","#$","Foreskin","."),3011820). assertion_content_comment(nartR('iTheFn','tPartTypeGallBladder'),s("The","gall","bladder",":","a","#$","GallBladder","."),3011821). assertion_content_comment(nartR('iTheFn','tPartTypeGroin'),s("The","groin",":","a","#$","Groin","."),3011822). assertion_content_comment(nartR('iTheFn','tPartTypeHeart'),s("The","heart",":","a","#$","Heart","."),3011823). assertion_content_comment(nartR('iTheFn','tPartTypeHepaticPortalVein'),s("The","portal","vein",":","a","#$","HepaticPortalVein","."),3012033). assertion_content_comment(nartR('iTheFn','tPartTypeHypothalamus'),s("The","hypothalamus",":","a","#$","Hypothalamus","."),3011824). assertion_content_comment(nartR('iTheFn','tPartTypeIleum'),s("The","ileum",":","an","#$","Ileum","."),3011825). assertion_content_comment(nartR('iTheFn','tPartTypeImmuneSystem'),s("The","immune","system",":","an","#$","ImmuneSystem","."),3011826). assertion_content_comment(nartR('iTheFn','tPartTypeJawbone'),s("The","jawbone",":","a","#$","Jawbone","."),3011829). assertion_content_comment(nartR('iTheFn','tPartTypeJaw'),s("The","jaw",":","a","#$","Jaw","."),3011828). assertion_content_comment(nartR('iTheFn','tPartTypeLargeIntestine'),s("The","large","intestine",":","a","#$","LargeIntestine","."),3012006). assertion_content_comment(nartR('iTheFn','tPartTypeLarynx'),s("The","larynx",":","a","#$","Larynx","."),3012007). assertion_content_comment(nartR('iTheFn','tPartTypeLimbicSystem'),s("The","limbic","system",":","a","#$","LimbicSystem","."),3012008). assertion_content_comment(nartR('iTheFn','tPartTypeLiver'),s("The","liver",":","a","#$","Liver","."),3012009). assertion_content_comment(nartR('iTheFn','tPartTypeLumbarVertebrae'),s("The","lumbar","spine",":","a","#$","LumbarVertebrae","."),3012010). assertion_content_comment(nartR('iTheFn','tPartTypeLymphaticSystem'),s("The","lymphatic","system",":","a","#$","LymphaticSystem","."),3012011). assertion_content_comment(nartR('iTheFn','tPartTypeMasticationMuscleSet'),s("The","mastication","muscle","set",":","a","#$","MasticationMuscleSet","."),3012013). assertion_content_comment(nartR('iTheFn','tPartTypeMedullaOblongata'),s("The","medulla","oblongata",":","a","#$","MedullaOblongata","."),3012014). assertion_content_comment(nartR('iTheFn','tPartTypeMidbrain'),s("The","midbrain",":","a","#$","Midbrain","."),3012015). assertion_content_comment(nartR('iTheFn','tPartTypeMouth'),s("The","mouth",":","a","#$","Mouth","."),3012016). assertion_content_comment(nartR('iTheFn','tPartTypeNasalSeptum'),s("The","nasal","septum",":","a","#$","NasalSeptum","."),3012017). assertion_content_comment(nartR('iTheFn','tPartTypeNeckAnimalBodyPart'),s("The","neck",":","a","#$","Neck-AnimalBodyPart","."),3012019). assertion_content_comment(nartR('iTheFn','tPartTypeNervousSystem'),s("The","nervous","system",":","a","#$","NervousSystem","."),3012020). assertion_content_comment(nartR('iTheFn','tPartTypeNose'),s("The","nose",":","a","#$","Nose","."),3012021). assertion_content_comment(nartR('iTheFn','tPartTypeOlfactorySystem'),s("The","olfactory","system",":","an","#$","OlfactorySystem","."),3012022). assertion_content_comment(nartR('iTheFn','tPartTypeOroPharynx'),s("The","oropharynx",":","an","#$","OroPharynx","."),3012023). assertion_content_comment(nartR('iTheFn','tPartTypePancreas'),s("The","pancreas",":","a","#$","Pancreas","."),3012024). assertion_content_comment(nartR('iTheFn','tPartTypePelvis'),s("The","pelvis",":","a","#$","Pelvis","."),3012025). assertion_content_comment(nartR('iTheFn','tPartTypePenis'),s("The","penis",":","a","#$","Penis","."),3012026). assertion_content_comment(nartR('iTheFn','tPartTypePericardium'),s("The","pericardium",":","a","#$","Pericardium","."),3012027). assertion_content_comment(nartR('iTheFn','tPartTypePeritoneum'),s("The","peritoneum",":","a","#$","Peritoneum","."),3012028). assertion_content_comment(nartR('iTheFn','tPartTypePharynx'),s("The","pharynx",":","a","#$","Pharynx","."),3012029). assertion_content_comment(nartR('iTheFn','tPartTypePinealBody'),s("The","pineal","gland",":","a","#$","PinealBody","."),3012030). assertion_content_comment(nartR('iTheFn','tPartTypePituitaryGland'),s("The","pituitary","gland",":","a","#$","PituitaryGland","."),3012031). assertion_content_comment(nartR('iTheFn','tPartTypePons'),s("The","pons","varolii",":","a","#$","Pons","."),3012032). assertion_content_comment(nartR('iTheFn','tPartTypeProstate'),s("The","prostate",":","a","#$","Prostate","."),3012034). assertion_content_comment(nartR('iTheFn','tPartTypeRectum'),s("The","rectum",":","a","#$","Rectum","."),3012036). assertion_content_comment(nartR('iTheFn','tPartTypeReproductiveSystem'),s("The","reproductive","system",":","a","#$","ReproductiveSystem","."),3012037). assertion_content_comment(nartR('iTheFn','tPartTypeRespiratorySystem'),s("The","respiratory","system",":","a","#$","RespiratorySystem","."),3012038). assertion_content_comment(nartR('iTheFn','tPartTypeRibCage'),s("The","rib","cage",":","a","#$","RibCage","."),3012039). assertion_content_comment(nartR('iTheFn','tPartTypeSacralVertebrae'),s("The","sacral","spine",":","a","#$","SacralVertebrae","."),3012040). 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assertion_content_comment(nartR('mobGraduateFn','tGroupedCollege'),s("The","collection","of","all","college","graduates",".","A","type","of","#$","Graduate",".","\"","(","#$","GraduateFn","#$","College",")","\"","is","an","#$","ExistenceDependentTerminalCollection","."),3033022). assertion_content_comment(nartR('mobGraduateFn','tGroupedHighSchool'),s("The","collection","of","all","high","school","graduates",".","A","type","of","#$","Graduate","and","#$","LiterateAgent","."),3011358). assertion_content_comment(nartR('mobGraduateFn','tGroupedMedicalSchool'),s("The","collection","of","all","medical","school","graduates",".","A","type","of","degree","granting","institution","graduate",".","\"","(","#$","GraduateFn","#$","MedicalSchool",")","\"","is","an","#$","ExistenceDependentTerminalCollection","."),3011478). assertion_content_comment(nartR('mobGraduateFn','tGroupedMiddleSchool'),s("The","collection","of","all","junior","high","graduates",".","A","type","of","#$","Graduate","."),3011431). assertion_content_comment(nartR('mobGraduateFn','tGroupedUniversity'),s("The","collection","of","all","university","graduates",".","A","type","of","degree","granting","institution","graduate","and","#$","LiterateAgent","."),3012100). assertion_content_comment(nartR('mobJuvenileFn','tClazzCarnivoreOrder'),s("The","collection","of","all","cubs",".","A","type","of","#$","JuvenileAnimal","and","#$","CarnivoreOrder","."),3011166). assertion_content_comment(nartR('mobJuvenileFn','tClazzCat'),s("The","collection","of","all","kittens",".","A","type","of","#$","Cat","and","#$","JuvenileAnimal","."),3011435). assertion_content_comment(nartR('mobJuvenileFn','tClazzCattleDomestic'),s("The","collection","of","all","calves","(","juvenile","cattle",")","A","type","of","#$","Cattle-Domestic","and","#$","JuvenileAnimal","."),3011043). assertion_content_comment(nartR('mobJuvenileFn','tClazzChicken'),s("The","collection","of","all","chicks","(","juvenile","chicken",")","A","type","of","#$","Chicken","and","#$","JuvenileAnimal","."),3011111). assertion_content_comment(nartR('mobJuvenileFn','tClazzDeer'),s("The","collection","of","all","fawns",".","A","type","of","#$","Deer","and","#$","JuvenileAnimal","."),3011246). assertion_content_comment(nartR('mobJuvenileFn','tClazzDog'),s("The","collection","of","all","puppies","(","juvenile","dogs",")","A","type","of","#$","JuvenileAnimal","and","#$","Dog","."),3011661). assertion_content_comment(nartR('mobJuvenileFn','tClazzHomoSapiens'),s("The","collection","of","all","juveniles",".","A","type","of","#$","JuvenileAnimal","and","#$","Person","."),3011432). assertion_content_comment(nartR('mobJuvenileFn','tClazzHorse'),s("The","collection","of","all","foals",".","A","type","of","#$","Horse","and","#$","JuvenileAnimal","."),3011261). assertion_content_comment(nartR('mobJuvenileFn','tClazzMaleHuman'),s("The","collection","of","all","boys","(","juvenile","male","humans",")","A","type","of","#$","JuvenileAnimal","and","#$","MaleHuman","."),3011049). assertion_content_comment(nartR('mobJuvenileFn','tClazzSheep'),s("The","collection","of","all","lambs",".","A","type","of","#$","Sheep","and","#$","JuvenileAnimal",".","The","lamb","is","a","#$","DomesticatedAnimalType","."),3296165). assertion_content_comment(nartR('mobMaleFn','mobWaitperson'),s("The","collection","of","all","waiters",".","A","type","of","#$","Waitperson","and","#$","MaleAnimal","."),3012120). assertion_content_comment(nartR('mobMaleFn',nartR('tColOfSubcollectionOfWithRelationFromTypeFn','mobBaggagePorter','employees','tGroupedHotelOrganization')),s("The","collection","of","all","bellboys",".","A","type","of","hotel","baggage","porter","and","#$","MaleHuman","."),3011026). assertion_content_comment(nartR('mobMaleFn','tClazzChicken'),s("The","collection","of","all","roosters",".","A","type","of","#$","Chicken","and","#$","MaleAnimal",".","The","rooster","is","a","#$","DomesticatedAnimalType","."),3296164). assertion_content_comment(nartR('mobMaleFn','tClazzDeer'),s("The","collection","of","all","bucks",".","A","type","of","#$","Deer","and","#$","MaleAnimal","."),3011344). assertion_content_comment(nartR('mobMaleFn','tClazzGoat'),s("The","collection","of","all","he","goats",".","A","type","of","#$","Goat","and","#$","MaleAnimal","."),3011028). assertion_content_comment(nartR('mobMaleFn','tClazzHorse'),s("The","collection","of","all","male","horses",".","A","type","of","#$","Horse","and","#$","MaleAnimal","."),3011758). assertion_content_comment(nartR('mobMaleFn','tClazzSheep'),s("The","collection","of","all","rams",".","A","type","of","#$","Sheep","and","#$","MaleAnimal","."),3011667). assertion_content_comment(nartR('mobPersonEnrolledInFn','tGroupedElementarySchool'),s("The","collection","of","all","grade","school","student",".","A","type","of","#$","Student","."),3011330). assertion_content_comment(nartR('mobPersonEnrolledInFn','tGroupedFlightSchool'),s("The","collection","of","flight","school","students",".","A","type","of","#$","Student","."),3011258). assertion_content_comment(nartR('mobPersonEnrolledInFn','tGroupedKindergartenInstitution'),s("The","collection","of","all","students","enrolled","in","kindergarten","institutions.A","type","of","#$","Kindergartner","."),5052606). assertion_content_comment(nartR('mobPersonEnrolledInFn','tGroupedMedicalSchool'),s("The","collection","of","all","medical","students",".","A","type","of","#$","Student",".","\"","Medical","student","\"","is","a","#$","PersonTypeByActivity","."),3011479). assertion_content_comment(nartR('mobPersonEnrolledInFn','tGroupedUniversity'),s("The","collection","of","all","university","students",".","A","type","of","#$","Student","."),3011138). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectBanjo'),s("The","collection","of","banjo","players",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011010). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectBassGuitarElectric'),s("The","collection","of","all","bass","guitarists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011017). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectBassViolin'),s("The","collection","of","bass","violin","players",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011018). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectBrassInstrument'),s("A","type","of","#$","MusicalInstrumentPlayer","."),3011070). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectCello'),s("The","collection","of","all","cellists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011097). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectClarinet'),s("A","sub-collection","of","#$","MusicalInstrumentPlayer",".","Each","instance","is","a","musician","who","plays","the","clarinet","."),1933022). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectClarinet'),s("The","collection","of","all","clarinet","players",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011118). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectElectronicMusicalKeyboard'),s("A","type","of","#$","MusicalInstrumentPlayer","."),3011221). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectFlute'),s("A","type","of","#$","MusicalInstrumentPlayer","."),3011260). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectGuitarAcoustic'),s("The","collection","of","all","acoustic","guitarists",",","who","are","people","that","play","the","acoustic","guitar",".","A","type","of","#$","MusicalInstrumentPlayer.","."),3010941). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectGuitar'),s("The","collection","of","all","guitarists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011340). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectKeyboardMusicalInstrument'),s("The","collection","of","all","keyboardists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011433). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectOrganMusicalInstrument'),s("The","collection","of","all","organists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011589). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectSaxophone'),s("The","collection","of","all","saxophonists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3011707). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectTrumpet'),s("The","collection","of","all","trumpeters",".","A","type","of","#$","HornPlayer","and","brass","instrument","player","."),3012096). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectViola'),s("The","collection","of","all","violists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3012112). assertion_content_comment(nartR('mobPlayerOfInstrumentFn','tObjectViolin'),s("The","collection","of","all","violinists",".","A","type","of","#$","MusicalInstrumentPlayer","."),3012111). assertion_content_comment(nartR('mobPractitionerFn','iEconomics'),s("The","collection","of","all","economic","experts",".","A","type","of","#$","HomoSapiens","."),3011212). assertion_content_comment(nartR('mobProductProviderFnSeller','tObjectBookCopy'),s("The","collection","of","all","book","sellers",".","A","type","of","#$","Vendor","."),3011036). assertion_content_comment(nartR('mobProductProviderFnSeller','tObjectClothingGeneric'),s("The","collection","of","all","fashion","retailers",".","A","type","of","#$","Vendor","."),3011244). assertion_content_comment(nartR('mobProductProviderFnSeller','tObjectFurniturePiece'),s("The","collection","of","all","furniture","sellers",".","A","type","of","#$","Vendor","."),3011278). assertion_content_comment(nartR('mobProductProviderFnSeller','tObjectToy'),s("The","collection","of","all","toy","sellers",".","A","type","of","#$","Vendor","."),3012086). assertion_content_comment(nartR('mobProductProviderFnSeller','tPartTypeModem'),s("The","collection","of","all","modem","retailers",".","A","type","of","#$","Vendor","."),3011532). assertion_content_comment(nartR('mobProfessionalFn','mobFigureSkater'),s("The","collection","of","professional","figure","skaters","."),1076026). assertion_content_comment(nartR('mobProfessionalFn','mobSkateboarder'),s("The","collection","of","professional","skateboarders","."),1086416). assertion_content_comment(nartR('mobProfessionalFn','mobWrestler'),s("The","collection","of","#$","Persons","who","perform","wrestling","for","pay","or","as","an","occupation"),1088167). assertion_content_comment(nartR('mobProfessionalFn','mobWrestler'),s("The","collection","of","all","pro","wrestlers",".","A","type","of","athlete","that","is","also","a","performing","artist","and","#$","Wrestler","."),3011640). assertion_content_comment(nartR('mobProfessorFn','iEconomics'),s("The","collection","of","all","professor","of","economics",".","A","type","of","#$","Professor","."),3011643). assertion_content_comment(nartR('mobProfessorFn','iHistoryFieldOfStudy'),s("The","collection","of","all","professor","of","history",".","A","type","of","#$","Professor",".","\"","(","#$","ProfessorFn","#$","History-FieldOfStudy",")","\"","is","a","#$","PersonTypeByOccupation","."),3011645). assertion_content_comment(nartR('mobProfessorFn','iPhilosophy'),s("The","collection","of","all","professor","of","philosophy",".","A","type","of","#$","Professor","."),3011646). assertion_content_comment(nartR('mobProfessorFn','iPhysics'),s("The","collection","of","all","professor","of","physics",".","A","type","of","#$","Professor","."),3011647). assertion_content_comment(nartR('mobProfessorFn',nartR('iFieldConcerningFn','tReligion')),s("A","type","of","#$","Professor","."),3011644). assertion_content_comment(nartR('mobPublisherOfPublicationTypeFn','tObjectNewspaperCopy'),s("The","collection","of","all","publishers","of","newspapers",".","A","#$","SpatiallyDisjointObjectType","."),3011658). assertion_content_comment(nartR('mobResidentFn','iCityOfAthensGreece'),s("A","sub-collection","of","#$","Person",".","Each","instance","is","a","resident","of","Athens","."),1921169). assertion_content_comment(nartR('mobResidentFn','iCityOfAthensGreece'),s("The","collection","of","all","Athenians",".","A","type","of","#$","HomoSapiens","."),3010994). assertion_content_comment(nartR('mobResidentFn','iContinentOfNorthAmerica'),s("The","collection","of","all","North","Americans",".","A","type","of","#$","HomoSapiens","."),3011561). assertion_content_comment(nartR('mobResidentFn','iLesbosIslandGreece'),s("A","sub-collection","of","#$","GreekPerson",".","Each","instance","is","a","resident","of","Lesbos","."),1922075). assertion_content_comment(nartR('mobTeacherFn','iHistoryFieldOfStudy'),s("The","collection","of","all","teacher","of","history",".","A","type","of","#$","Teacher","."),3011774). assertion_content_comment(nartR('mobUserOfSystemWithLocalNameFn','iGlassBoxEnvironment01',"JaneJones"),s("The","most","significant","instance","of","IntelligenceAnalyst","used","in","the","Nooescape-TheProgram","prototype","demo","."),1948117). assertion_content_comment(nartR('mobUserOfSystemWithLocalNameFn','iGlassBoxEnvironment01',"JessicaJosephs"),s("An","instance","of","IntelligenceAnalyst","used","in","the","Nooescape-TheProgram","prototype","demo","."),1948151). assertion_content_comment(nartR('mobUserOfSystemWithLocalNameFn','iGlassBoxEnvironment01',"JimJefferson"),s("An","instance","of","IntelligenceAnalyst","used","in","the","Nooescape-TheProgram","prototype","demo","."),1948165). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actAddingMixedFractions'),s("When","adding","mixed","fractions",",","the","agent","converts","both","mixed","fractions","to","simple","fractions","and","then","adds","."),7169811). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actCompletelySimplifyingAMathExpressionVariableBindingsKnown'),s("Note","that","this","process","model","doesn","'","t","specify","all","the","subEvents",".","This","is","because","the","full","event","structure","can","'","t","be","known","in","advance","."),5555740). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actCompletelySimplifyingAMathExpressionVariablesButNoVariableBindings'),s("Note","that","this","process","model","doesn","'","t","specify","all","the","subEvents",".","This","is","because","the","full","event","structure","can","'","t","be","known","in","advance","."),5555714). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actEnsureCommonDenominatorsOfSimpleFractionsMultiplesCase'),s("Models","the","case","in","which","the","denominator","of","the","first","input","is","a","multiple","of","the","denominator","of","the","second","input","."),5705111). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actMultiplyingAMixedFractionAndASimpleFraction'),s("This","is","a","correct","process","model","for","the","cases","where","the","first","factor","id","the","mixed","number","and","the","second","factor","is","the","simple","fraction",".","Cf",".","(","#$","SuccessfulProcessForProblemTypeMtFn","#$","MultiplyingAMixedFractionAndASimpleFraction","2",")","for","the","cases","where","the","order","of","the","factors","is","reversed","."),7736760). 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assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actMultiplyingTwoSimpleFractions'),s("This","model","is","not","executable","because","it","relied","on","a","rule","that","is","now","backward","due","to","expense","and","is","deprecated",".","It","'","s","being","kept","because","many","Bella","graphs","depend","on","it",".","Use","(","#$","SuccessfulProcessForProblemTypeMtFn","#$","MultiplyingTwoSimpleFractions","1",")","instead","."),6710704). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actPerformingAnOperationOnBothSidesOfAMathStatement'),s("In","this","model",",","the","agent","appends","an","operation","to","each","side","of","a","#$","MathematicalStatement","and","then","simplifies","both","sides",".","This","is","the","method","employed","in","McGraw-Hill","'","s","Math","Connects","math","textbook","."),5556311). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actSelectingASubExpressionToSimplify'),s("This","model","is","intended","to","be","mostly","empty","."),5615514). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actSubtractingAMixedFractionFromAnInteger'),s("This","model","requires","the","integer","to","be","larger","than","the","mixed","fraction","."),6510383). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actSubtractingAnIntegerFromAMixedFraction'),s("When","subtracting","an","integer","from","a","mixed","fraction",",","the","agent","converts","the","integer","into","an","equivalent","mixed","fraction","and","then","subtracts","."),7161106). assertion_content_comment(nartR('mtCanonicalProcessForProblemTypeMtFn','actSubtractingMixedFractionsFractionalPartOfMinuendGreaterOrEqual'),s("In","this","model",",","wholes","and","fractions","are","subtracted","individually","."),6414586). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TestTopNode"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","TestTopNode","node","."),1906429). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TestTopNode.TestChildNode"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","TestChildNode","node","."),1906437). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TopNode.CyclistEmailAddressChecking.CyclistEmailAddressCheckingEmailSender"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","CyclistEmailAddressCheckingEmailSender","node","."),2167243). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TopNode.CyclistEmailAddressChecking"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","CyclistEmailAddressChecking","node","."),2167235). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TopNode.CycorpRefrigeratorMassEMailSending.CycorpRefrigeratorMassEmailSender"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","CycorpRefrigeratorMassEmailSender","node","."),2167259). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TopNode.CycorpRefrigeratorMassEMailSending"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","CycorpRefrigeratorMassEMailSending","node","."),2167251). assertion_content_comment(nartR('mtCBLScriptExecutionContextFn',"TopNode"),s("The","#$","CycBehaviorLanguageSpindle","#$","ScriptExecutionContext","that","contains","the","state","axioms","of","the","TopNode","node","."),2167227). assertion_content_comment(nartR('mtContextOfPCWFn','i2001ASpaceOdysseyTheNarrative'),s("A","context","in","which","exactly","those","propositions","which","are","true","in","the","Narrative","#$","2001-ASpaceOdyssey-TheNarrative",",","are","true","."),560604). assertion_content_comment(nartR('mtContextOfPCWFn','iAdventuresOfHuckleberryFinn'),s("A","context","in","which","exactly","those","propositions","which","are","true","in","the","story","of","#$","AdventuresOfHuckleberryFinn",",","are","true","."),560600). assertion_content_comment(nartR('mtContextOfPCWFn','iBatmanAndRobinTheMovie'),s("In","this","Mt","go","assertions","that","are","true","|","|","in","the","context","of","#$","BatmanAndRobin-TheMovie","."),560634). 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assertion_content_comment(nartR('tClazzBelieverFn','iNationalistIdeology'),s("A","sub-collection","of","#$","Advocate",".","Each","instance","is","an","advocate","of","national","independence","of","or","a","strong","national","government","."),1922748). assertion_content_comment(nartR('tClazzBelieverFn','iNationalistIdeology'),s("The","collection","of","all","nationalists",".","A","type","of","#$","Advocate","."),3011542). assertion_content_comment(nartR('tClazzBelieverFn','iNaturism'),s("The","collection","of","all","naturists",".","A","type","of","#$","HomoSapiens","."),3011544). assertion_content_comment(nartR('tClazzBelieverFn','iPacifism'),s("The","collection","of","all","pacifists",".","A","type","of","#$","HomoSapiens",".","\"","Pacifist","\"","is","an","#$","IntelligentAgentTypeByBeliefSystem","."),3011597). assertion_content_comment(nartR('tClazzBelieverFn','iProgressivism'),s("The","collection","of","all","progressives",".","A","type","of","#$","HomoSapiens","."),3011648). assertion_content_comment(nartR('tClazzBelieverFn','iSexism'),s("The","collection","of","all","sexists",".","A","type","of","#$","HomoSapiens",".","\"","Sexist","\"","is","an","#$","IntelligentAgentTypeByBeliefSystem","."),3011716). assertion_content_comment(nartR('tClazzBelieverFn','iShiiteIslam'),s("The","collection","of","all","Shiites",".","A","type","of","#$","HomoSapiens","."),3011719). assertion_content_comment(nartR('tClazzBelieverFn','iWahhabism'),s("The","collection","of","all","Whabbists",".","An","#$","IntelligentAgentTypeByBeliefSystem","."),3012130). assertion_content_comment(nartR('tClazzBelieverFn','iXenophobia'),s("The","collection","of","all","xenophobes",".","A","type","of","#$","HomoSapiens","."),3012139). assertion_content_comment(nartR('tClazzCitizenFn','iRomanEmpire'),s("The","collection","of","all","ancient","Romans",".","A","type","of","#$","HomoSapiens","."),3010973). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actBoating'),s("The","collection","of","all","boating","accessories",".","A","type","of","#$","Artifact","."),3011035). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actDancingHuman'),s("The","collection","of","all","dance","accessories",".","A","type","of","#$","Artifact","."),3011171). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actGymnasticsSportsEvent'),s("The","collection","of","all","gymnastics","accessories",".","A","type","of","#$","Artifact","."),3011341). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actInLineSkating'),s("The","collection","of","all","inline","skating","accessories",".","A","type","of","#$","Artifact","."),3011411). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actLiftingWeights'),s("The","collection","of","all","weightlifting","accessories",".","A","type","of","#$","Artifact","."),3012128). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actMartialArtsActivityAsian'),s("The","collection","of","all","martial","arts","accessories",".","A","type","of","#$","Artifact","."),3011466). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actRunning'),s("The","collection","of","all","running","accessories",".","A","type","of","#$","Artifact","."),3011698). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actScubaDiving'),s("The","collection","of","all","scuba","diving","accessories",".","A","type","of","#$","Artifact","."),3011711). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actSkateboarding'),s("The","collection","of","all","skateboarding","accessories",".","A","type","of","#$","Artifact","."),3011724). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actSnowboarding'),s("The","collection","of","all","snowboarding","accessories",".","A","type","of","#$","Artifact","."),3011733). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actSurfing'),s("The","collection","of","all","surfing","accessories",".","A","type","of","#$","Artifact","."),3011766). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actTeamSportsCompetition'),s("The","collection","of","all","team","sports","accessories",".","A","type","of","#$","Artifact","."),3011775). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actTravelTripEvent'),s("The","collection","of","all","travel","accessories",".","An","#$","ArtifactTypeByGenericCategory","."),3012092). assertion_content_comment(nartR('tColOfAccessoryFnActivity','actWeddingEventGeneric'),s("The","collection","of","all","wedding","accessories",".","A","type","of","#$","Artifact","."),3012127). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iBadminton')),s("The","collection","of","all","badminton","accessories",".","A","type","of","#$","Artifact","."),3011006). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iBaseballTheGame')),s("The","collection","of","all","baseball","accessories",".","A","type","of","#$","Artifact","."),3011012). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iBoxingSportCW')),s("The","collection","of","all","boxing","accessories",".","A","type","of","#$","Artifact","."),3011045). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iFootballAmerican')),s("The","collection","of","all","football","accessories",".","A","type","of","#$","Artifact","."),3011265). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iGolf')),s("The","collection","of","all","golf","accessories",".","A","type","of","#$","Artifact","."),3011324). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iHockey')),s("The","collection","of","all","hockey","accessories",".","A","type","of","#$","Artifact","."),3011381). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iLacrosse')),s("The","collection","of","all","lacrosse","accessories",".","A","type","of","#$","Artifact","."),3011437). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iRacquetballTheGame')),s("The","collection","of","all","raquetball","accessories",".","A","type","of","#$","Artifact","."),3011670). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iRugby')),s("The","collection","of","all","rugby","accessories",".","A","type","of","#$","Artifact","."),3011697). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iSoccer')),s("The","collection","of","all","soccer","accessories",".","A","type","of","#$","Artifact","."),3011734). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iSoftballTheGame')),s("The","collection","of","all","softball","accessories",".","A","type","of","#$","Artifact","."),3011737). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iSquashTheGame')),s("The","collection","of","all","squash","accessories",".","A","type","of","#$","Artifact","."),3011746). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iTennisTheGame')),s("The","collection","of","all","tennis","accessories",".","A","type","of","#$","PhysicalDevice","."),3011780). assertion_content_comment(nartR('tColOfAccessoryFnActivity',nartR('actPlayingFn','iVolleyball')),s("The","collection","of","all","volleyball","accessories",".","A","type","of","#$","Artifact","."),3012116). assertion_content_comment(nartR('tColOfAerosolizedFn','tBotulinumToxin'),s("The","collection","of","all","aerosolized","botulinum","toxin",".","A","type","of","#$","BotulinumToxin","and","#$","AerosolStuff","."),3010945). assertion_content_comment(nartR('tColOfAlternativeBeliefFn','iPhysics'),s("The","collection","of","all","alternative","physics",".","A","type","of","#$","Alternative","and","#$","BeliefSystem","."),3010961). assertion_content_comment(nartR('tColOfAlternativeBeliefFn','iScience'),s("The","collection","of","all","alternative","science",".","A","type","of","#$","Alternative","and","#$","BeliefSystem","."),3010962). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tGroupedCostume','mobFemaleChild'),s("The","collection","of","all","girls","'","costumes",".","A","type","of","clothing","used","by","girls","and","#$","Costume","."),3011317). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tGroupedCostume','mobMaleChild'),s("The","collection","of","all","boys","'","costumes",".","A","type","of","clothing","used","by","boys","and","#$","Costume","."),3011053). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tGroupedUniform','mobFemaleChild'),s("The","collection","of","all","girls","'","uniforms",".","A","type","of","clothing","used","by","girls","and","#$","Uniform","."),3011323). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tGroupedUniform','mobMaleChild'),s("The","collection","of","all","boys","'","uniforms",".","A","type","of","clothing","used","by","boys","and","#$","Uniform","."),3011067). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectAthleticClothing','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","athletic","clothing",".","A","type","of","#$","AthleticClothing","and","#$","MensClothing","."),3011481). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectBootFootwear','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","boots",".","A","type","of","#$","Boot-Footwear","and","#$","MensClothing","."),3011482). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectBootFootwear','mobFemaleChild'),s("The","collection","of","all","girls","'","boots",".","A","type","of","girls","'","footwear","and","#$","Boot-Footwear","."),3011299). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectBootFootwear','mobMaleChild'),s("The","collection","of","all","boys","'","boots",".","A","type","of","boys","'","footwear","and","#$","Boot-Footwear","."),3011051). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectCasualShoe','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","casual","shoes",".","A","type","of","men","'","s","shoe","and","#$","CasualShoe","."),3011483). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingGeneric','mobFemaleChild'),s("The","collection","of","all","girls","'","clothing",".","A","type","of","#$","Clothing-Generic","."),3011128). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingGeneric','mobHumanInfant'),s("The","collection","of","all","infants","'","clothing",".","A","type","of","#$","Clothing-Generic","."),3011129). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingGeneric','mobHumanTeenager'),s("The","collection","of","all","teen","apparel",".","A","type","of","#$","Clothing-Generic","."),3011776). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingGeneric','mobHumanToddler'),s("The","collection","of","all","toddlers","'","clothing",".","A","type","of","#$","Clothing-Generic","."),3011130). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingGeneric','mobMaleChild'),s("The","collection","of","all","boys","'","clothing",".","A","type","of","#$","Clothing-Generic","."),3011127). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingItem','mobFemaleChild'),s("The","collection","of","all","girls","'","clothing",".","A","type","of","#$","ChildrensClothing","and","#$","ClothingItem","."),3011300). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingItem','mobHumanInfant'),s("The","collection","of","all","baby","apparel",".","A","type","of","#$","ChildrensClothing","and","#$","ClothingItem","."),3010998). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectClothingItem','mobMaleChild'),s("The","collection","of","all","boys","apparel",".","A","type","of","#$","ChildrensClothing","and","#$","ClothingItem","."),3011068). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectCoat','mobFemaleChild'),s("The","collection","of","all","girls","'","coats",".","A","type","of","girls","'","outerwear","and","#$","Coat","."),3011301). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectCoat','mobMaleChild'),s("The","collection","of","all","boys","'","coats",".","A","type","of","boys","'","outerwear","and","#$","Coat","."),3011052). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectDress','mobFemaleChild'),s("The","collection","of","all","girls","'","dresses",".","A","type","of","#$","Dress","and","girls","'","clothing","."),3011302). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectDress','mobHumanInfant'),s("The","collection","of","all","infant","dresses",".","A","type","of","#$","Dress","and","baby","apparel","."),3011409). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectDress',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","dresses",".","A","type","of","#$","Dress","and","juniors","'","clothing","."),3011514). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectDressShirt','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","dress","shirts",".","A","type","of","men","'","s","shirt","and","#$","DressShirt","."),3011484). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectDressShoe','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","dress","shoes",".","A","type","of","men","'","s","shoe","and","#$","DressShoe","."),3011485). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectJacket','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","jackets",".","A","type","of","men","'","s","outerwear","and","#$","Jacket","."),3011486). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectJacket','mobFemaleChild'),s("The","collection","of","all","girls","jackets",".","A","type","of","girls","'","outerwear","and","#$","Jacket","."),3011318). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectJacket','mobMaleChild'),s("The","collection","of","all","boys","jackets",".","A","type","of","boys","'","outerwear","and","#$","Jacket","."),3011069). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectJeans','mobFemaleChild'),s("The","collection","of","all","girls","'","jeans",".","A","type","of","#$","Jeans","and","girls","'","clothing","."),3011319). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectJeans',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","jeans",".","A","type","of","misses","'","pants","and","#$","Jeans","."),3011511). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectLongPants','mobFemaleChild'),s("The","collection","of","all","girls","'","slacks",".","A","type","of","girls","'","clothing","and","#$","LongPants","."),3011320). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectLongPants','mobMaleChild'),s("The","collection","of","all","boys","'","pants",".","A","type","of","kids","'","clothing","used","for","boys",",","#$","LongPants",",","and","boys","apparel","."),3011057). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectLongPants',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","pants",".","A","type","of","misses","'","pants","and","#$","LongPants","."),3011512). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectLongSleeveShirt','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","long-sleeve","shirts",".","A","type","of","men","'","s","shirt","and","#$","LongSleeveShirt","."),3011487). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectLongSleeveShirt',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","long","sleeve","shirts",".","A","type","of","misses","shirt","and","#$","LongSleeveShirt","."),3011515). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectMoccasin','mobFemaleChild'),s("The","collection","of","all","girls","'","moccasins",".","A","type","of","#$","Moccasin","and","girls","'","footwear","."),3011304). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectMoccasin','mobMaleChild'),s("The","collection","of","all","boys","'","moccasins",".","A","type","of","#$","Moccasin","and","boys","'","footwear","."),3011055). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOveralls','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","overalls",".","A","type","of","clothing","bottom","used","by","men","and","#$","Overalls","."),3011489). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOverGarment','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","outerwear",".","A","type","of","#$","MensClothing","and","#$","OverGarment","."),3011488). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOverGarment','mobFemaleChild'),s("The","collection","of","all","girls","'","outerwear",".","A","type","of","girls","'","clothing","and","#$","OverGarment","."),3011305). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOverGarment','mobHumanInfant'),s("The","collection","of","all","baby","outerwear",".","A","type","of","baby","apparel","and","#$","OverGarment","."),3010999). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOverGarment','mobMaleChild'),s("The","collection","of","all","boys","'","outerwear",".","A","type","of","boys","apparel","and","#$","OverGarment","."),3011056). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectOverGarment',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","outerwear",".","A","type","of","juniors","'","clothing","and","#$","OverGarment","."),3011516). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectPants',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","pants",".","A","type","of","juniors","'","clothing","and","#$","Pants","."),3011513). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSandal','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","sandals",".","A","type","of","#$","Sandal","and","#$","MensClothing","."),3011490). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSandal','mobFemaleChild'),s("The","collection","of","all","girls","'","sandals",".","A","type","of","girls","'","footwear","and","#$","Sandal","."),3011306). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSandal','mobMaleChild'),s("The","collection","of","all","boys","'","sandals",".","A","type","of","boys","'","footwear","and","#$","Sandal","."),3011058). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShirt','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","shirts",".","A","type","of","#$","Shirt","and","#$","MensClothing","."),3011491). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShirt','mobFemaleChild'),s("The","collection","of","all","girls","'","shirts",".","A","type","of","girls","'","clothing","and","#$","Shirt","."),3011307). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShirt','mobHumanInfant'),s("The","collection","of","all","baby","shirts",".","A","type","of","baby","apparel","and","#$","Shirt","."),3011000). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShirt','mobMaleChild'),s("The","collection","of","all","boys","'","shirts",".","A","type","of","boys","apparel","and","#$","Shirt","."),3011059). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShirt',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","shirts",".","A","type","of","juniors","'","clothing","and","#$","Shirt","."),3011517). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShoe','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","shoes",".","A","type","of","#$","MensClothing","and","#$","Shoe","."),3011492). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShoe','mobFemaleChild'),s("The","collection","of","all","girls","'","footwear",".","A","type","of","girls","'","clothing","and","#$","Shoe","."),3011303). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShoe','mobMaleChild'),s("The","collection","of","all","boys","'","footwear",".","A","type","of","boys","apparel","and","#$","Shoe","."),3011054). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortPants','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","shorts",".","A","type","of","#$","ShortPants","and","#$","MensClothing","."),3011494). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortPants','mobFemaleChild'),s("The","collection","of","all","girls","'","shorts",".","A","type","of","#$","ShortPants","and","girls","'","clothing","."),3011308). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortPants','mobHumanInfant'),s("The","collection","of","all","baby","shorts",".","A","type","of","baby","apparel","and","#$","ShortPants","."),3011001). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortPants','mobMaleChild'),s("The","collection","of","all","boys","'","shorts",".","A","type","of","kids","'","clothing","used","for","boys",",","boys","apparel",",","and","#$","ShortPants","."),3011060). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortPants',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","shorts",".","A","type","of","#$","ShortPants","and","juniors","'","clothing","."),3011519). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortSleeveShirt','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","short-sleeve","shirts",".","A","type","of","men","'","s","shirt","and","#$","ShortSleeveShirt","."),3011493). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectShortSleeveShirt',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","short-sleeve","shirts",".","A","type","of","misses","shirt","and","#$","ShortSleeveShirt","."),3011518). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSkirt','mobFemaleChild'),s("The","collection","of","all","girls","'","skirts",".","A","type","of","#$","Skirt","and","girls","'","clothing","."),3011309). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSkirt',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","skirts",".","A","type","of","#$","Skirt","and","juniors","'","clothing","."),3011520). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSleepWear','mobFemaleChild'),s("The","collection","of","all","girls","'","sleepwear",".","A","type","of","#$","SleepWear","and","girls","'","clothing","."),3011310). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSleepWear','mobMaleChild'),s("The","collection","of","all","boys","'","sleepwear",".","A","type","of","#$","SleepWear","and","boys","apparel","."),3011061). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSlipper','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","slippers",".","A","type","of","#$","Slipper","."),3011495). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSlipper','mobFemaleChild'),s("The","collection","of","all","girls","'","slippers",".","A","type","of","girls","'","footwear","and","#$","Slipper","."),3011311). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSlipper','mobMaleChild'),s("The","collection","of","all","boys","'","slippers",".","A","type","of","boys","'","footwear","and","#$","Slipper","."),3011062). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSock','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","socks",".","A","type","of","#$","Sock","and","#$","MensClothing","."),3011497). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSock','mobFemaleChild'),s("The","collection","of","all","girls","'","socks",".","A","type","of","#$","Sock","and","girls","'","clothing","."),3011312). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSock','mobHumanInfant'),s("The","collection","of","all","baby","socks",".","A","type","of","#$","Sock","and","baby","apparel","."),3011002). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSock','mobMaleChild'),s("The","collection","of","all","boys","'","socks",".","A","type","of","#$","Sock","and","boys","apparel","."),3011063). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSweater','mobFemaleChild'),s("The","collection","of","all","girls","'","sweaters",".","A","type","of","#$","Sweater","and","girls","'","clothing","."),3011313). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSweater','mobHumanInfant'),s("The","collection","of","all","baby","sweaters",".","A","type","of","#$","Sweater","and","baby","apparel","."),3011003). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSweater','mobMaleChild'),s("The","collection","of","all","boys","'","sweaters",".","A","type","of","#$","Sweater","and","boys","apparel","."),3011064). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSweater',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","sweaters",".","A","type","of","#$","Sweater","and","juniors","'","clothing","."),3011521). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSwimWear','mobFemaleChild'),s("The","collection","of","all","girls","'","swimwear",".","A","type","of","girls","'","clothing","and","#$","SwimWear","."),3011321). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectSwimWear','mobMaleChild'),s("The","collection","of","all","boys","'","swimwear",".","A","type","of","boys","apparel","and","#$","SwimWear","."),3011065). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTankTop','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","tank","tops",".","A","type","of","#$","TankTop","and","men","'","s","shirt","."),3011499). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTankTop',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","tank","tops",".","A","type","of","#$","TankTop","and","misses","shirt","."),3011523). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTights','mobFemaleChild'),s("The","collection","of","all","girls","'","tights",".","A","type","of","#$","Tights","and","girls","'","clothing","."),3011315). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTShirt','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","t-shirts",".","A","type","of","men","'","s","shirt","and","#$","T-Shirt","."),3011498). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTShirt','mobFemaleChild'),s("The","collection","of","all","girls","'","t","shirts",".","A","type","of","girls","'","shirt","and","#$","T-Shirt","."),3011314). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectTShirt',nartR('mobFemaleFn','mobHumanTeenager')),s("The","collection","of","all","misses","t","shirts",".","A","type","of","misses","shirt","and","#$","T-Shirt","."),3011522). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectUnderwear','mobFemaleChild'),s("The","collection","of","all","girls","'","underwear",".","A","type","of","girls","'","clothing","and","#$","Underwear","."),3011322). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectUnderwear','mobMaleChild'),s("The","collection","of","all","boys","'","underwear",".","A","type","of","boys","apparel","and","#$","Underwear","."),3011066). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectVest','mobAdultMaleHuman'),s("The","collection","of","all","men","'","s","vests",".","A","type","of","#$","Vest","and","#$","MensClothing","."),3011500). assertion_content_comment(nartR('tColOfArtifactTypeForUserTypeFn','tObjectWindbreaker','mobFemaleChild'),s("The","collection","of","all","girls","'","windbreakers",".","A","type","of","girls","'","outerwear","and","#$","Windbreaker","."),3011316). assertion_content_comment(nartR('tColOfBacterialSporeFn','tClazzClostridiumBotulinum'),s("The","collection","of","all","Clostridium","botulinum","spores",".","A","type","of","#$","ClostridiumBotulinum-Species","and","#$","Spore-DormantBacterium","."),3011125). assertion_content_comment(nartR('tColOfBurntFn',nartR('tPartTypeFruitFn','tClazzAlmondTree')),s("The","collection","of","all","burnt","almond",".","A","type","of","#$","Burnt",",","#$","EdibleFruit",",","#$","EdibleNut",",","and","#$","Nut-TheFruit","."),3011076). assertion_content_comment(nartR('tColOfChemicalSubstanceFn',nartR('tGroupedMoleculeFn','tHydrogen')),s("The","collection","of","all","H2",".","A","type","of","#$","Gaseous-StateOfMatter",".","H2","is","a","#$","ChemicalSubstanceType","."),3011533). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tAcetateIon'),s("The","collection","of","samples","of","the","conjugate","base","of","acetic","acid",".","Its","formula","is","C2H3O2","(","-",")"),1266445). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tAmmoniumIon'),s("The","collection","of","samples","of","ammonium","ions",".","Its","instances","are","moderately","weak","acids",".","Its","formula","is","NH4","+"),1266281). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tCarbonateIon'),s("The","collection","of","samples","of","carbonate","(","CO3","(","-2",")",")"),1266494). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tChlorideIon'),s("The","collection","of","samples","of","the","chloride","ion","(","Cl-",")"),1266376). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tDihydrogenPhosphateIon'),s("The","collection","of","samples","of","H2PO4-",";","the","ion","that","is","the","result","of","a","phosphoric","acid","atom","giving","up","a","hydrogen","proton",".","Instances","of","this","collection","can","act","as","a","moderately","weak","acid","and","moderately","weak","base"),1266258). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tFluorideIon'),s("The","collection","of","samples","of","(","F-",")",";","The","fluoride","ion","."),1266420). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tGroupedPhosphateIon'),s("The","collection","of","samples","of","phosphate","ions","(","PO4","(","-3",")",")"),1266513). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tGroupedProkaryoticDNAMolecule'),s("The","collection","of","all","prokaryotic","DNA",".","A","#$","ChemicalSubstanceType","."),3011650). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tGroupedRNAMolecule'),s("The","collection","of","all","RNA",".","A","#$","ChemicalSubstanceType","."),3011691). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrideIon'),s("The","collection","of","samples","of","(","H-",")"),1266554). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenCarbonateIon'),s("The","collection","of","samples","of","HCO3-",".","Instances","can","act","as","a","moderately","weak","acid","and","as","a","moderately","weak","base","."),1266331). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenChromateIon'),s("The","collection","of","samples","of","hydrogen","chromate","ions",";","HCrO4","(","-1",")"),1271260). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenPeroxideMolecule'),s("The","collection","of","all","peroxide",".","A","type","of","#$","WeakElectrolyte","and","#$","InorganicMaterial",".","H2O2","is","an","#$","AcidType-Monoprotic",",","an","#$","IonicDecomposableCompoundType",",","an","#$","AcidType-Weak",",","an","#$","AcidType-Arrhenius",",","and","a","#$","PeroxideType","."),3011400). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenPeroxideMolecule'),s("The","collection","of","samples","of","hydrogen","peroxide",";","H2O2","."),1114659). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenPhosphateIon'),s("The","collection","of","samples","of","HPO4","(","-2",")","Instances","can","act","as","a","weak","acid","and","a","weak","base","."),1266354). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenSelenateIon'),s("The","collection","of","samples","of","hydrogen","selenate","ions",";","HSeO4","."),1271279). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHydrogenSulfideIon'),s("The","collection","of","samples","of","hydrogen","sulfide","ions","(","HS-",")"),1266467). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tHypochloriteIon'),s("The","collection","of","samples","of","ClO","(","-1",")"),1271603). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tMethaneIon'),s("The","collection","of","samples","of","(","CH3-",")","Instances","are","methane","minus","one","hydrogen","proton","."),1266575). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tNitrateIon'),s("The","collection","of","samples","of","(","NO3-",")",";","The","nitrate","ion","."),1265502). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tOxideIon'),s("The","collection","of","samples","of","O","(","2-",")"),1266538). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tSulfateIon'),s("The","collection","of","samples","of","(","SO4","(","-2",")",")",";","The","sulfate","ion","."),1266397). assertion_content_comment(nartR('tColOfChemicalSubstanceFn','tSulfiteIon'),s("The","collection","of","all","sulfite","ions",",","SO3","(","2-",")","A","type","of","#$","WeakElectrolyte","and","#$","InorganicMaterial",".","A","#$","ChemicalCompoundTypeByChemicalSpecies","."),3011761). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','actCollegeAndUniversitySportsEvent',nartR('actGameFn','iBasketballTheGame')),s("The","collection","of","all","college","basketball","games",".","A","type","of","#$","CollegeAndUniversitySportsEvent","and","basketball","game","."),3032555). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','actCooperationEvent','actEconomicAction'),s("The","collection","of","all","economic","cooperation",".","A","type","of","#$","EconomicAction","and","#$","CooperationEvent","."),3011211). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','actUndressing','actEntertainmentEvent'),s("The","collection","of","all","strip","shows",".","A","type","of","#$","Undressing","and","#$","EntertainmentEvent","."),3011757). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','iboSymbolicThing','cwSongCW'),s("The","collection","of","all","anthems",".","A","type","of","#$","Song-CW","."),3010978). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','mobDairyBeverageDeliveryProfessional','mobAdultMaleHuman'),s("The","collection","of","all","milk","men",".","A","type","of","#$","DairyBeverageDeliveryProfessional","and","#$","AdultMaleHuman","."),3011507). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','mobNude','mobPerson'),s("The","collection","of","all","nude","people",".","A","type","of","#$","Nude","."),3011568). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','mobStudent','mobHumanChild'),s("The","collection","of","all","school","children",".","A","type","of","#$","HumanChild","and","#$","Student","."),3011708). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','mobTerrorist','mobStateSponsoredTerroristAgent'),s("The","collection","of","all","state-sponsored","terrorists",".","A","type","of","#$","State-SponsoredTerroristAgent","and","#$","Terrorist","."),3011750). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tClazzComputerHardwareMarketCategory',nartR('tGroupedGroupFn','tGroupedSystemOfDevices')),s("The","collection","of","all","computer","hardware",".","A","type","of","group","of","system","of","devices","and","#$","ComputerHardwareMarketCategory","."),3011146). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tClazzDutchPerson','mobTourist'),s("The","collection","of","all","Dutch","tourists",".","A","type","of","European","tourist","and","#$","DutchPerson","."),3011206). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tClazzNigerianPerson','mobSoldier'),s("The","collection","of","all","Nigerian","soldiers",".","A","type","of","#$","NigerianPerson","and","#$","Soldier","."),3011558). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tClazzOldWorldPolecat','tClazzDomesticatedAnimal'),s("The","collection","of","all","domesticated","ferrets",".","A","type","of","#$","OldWorldPolecat",",","#$","Animal-HumanFoodSource",",","and","#$","DomesticatedAnimal","."),3011197). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tFried','tChickenMeat'),s("The","collection","of","all","fried","chicken",".","A","type","of","#$","Chicken-Meat","and","#$","Fried","."),3011274). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tGroupedInternationalOrganization','tGroupedTerroristGroup'),s("The","collection","of","all","international","terrorist","groups",".","A","type","of","#$","InternationalOrganization","and","#$","TerroristGroup","."),3011418). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tGroupedRevoltOrganization','tGroupedGuerillaForce'),s("The","collection","of","all","guerilla","groups",".","A","type","of","#$","GuerillaForce","and","#$","RevoltOrganization","."),3011338). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tGroupedSportsLeague',nartR('tGroupedGroupFn','tGroupedBasketballTeam')),s("The","collection","of","all","basketball","leagues",".","A","type","of","group","of","basketball","teams","and","#$","SportsLeague","."),3011016). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tGroupedTerroristGroup','mobStateSponsoredTerroristAgent'),s("The","collection","of","all","state-sponsored","terrorist","organizations",".","A","type","of","#$","State-SponsoredTerroristAgent","and","#$","TerroristGroup","."),3011751). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectAgriculturalImplement','tObjectLandTransportationVehicle'),s("The","collection","of","all","agricultural","vehicles",".","A","type","of","#$","AgriculturalImplement","and","#$","LandTransportationVehicle","."),3010950). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectBronzeStuff','tObjectArtObject'),s("The","collection","of","all","bronzes",".","A","type","of","#$","Bronze-Stuff","and","#$","ArtObject","."),3011074). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectBustSculpture','tObjectReliefSculpture'),s("The","collection","of","all","relief","busts",".","A","type","of","#$","Bust-Sculpture","and","#$","Relief-Sculpture","."),3011680). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectHelicopter','tObjectMilitaryAircraft'),s("the","collection","of","all","|","|","helicopters","used","for","military","purposes"),1078743). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectMachineGun','tObjectHandgun'),s("The","collection","of","all","machine","pistols",".","A","type","of","#$","Handgun","and","#$","MachineGun","."),3011453). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectMechanicalDevice','tPumpGeneric'),s("The","collection","of","all","mechanical","pumps",".","A","type","of","#$","Pump-Generic","and","#$","MechanicalDevice",".","\"","Mechanical","pump","\"","is","a","#$","SpatiallyDisjointObjectType","."),3011471). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectMilitaryWeapon','tObjectExplosiveDevice'),s("The","collection","of","all","explosive","ordnance",".","A","type","of","#$","ExplosiveDevice","and","#$","MilitaryWeapon","."),3011234). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectMummifiedRemains',nartR('tColOfDeadPhysicalRemainsFn','tClazzHomoSapiens')),s("The","collection","of","all","mummified","human","remains",".","A","type","of","#$","MummifiedRemains","and","dead","human","body","."),3011540). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectOfficeFurniture','tObjectWagon'),s("The","collection","of","all","office","carts",".","A","type","of","#$","OfficeFurniture","and","#$","Wagon","."),3011573). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectStemware','tObjectDrinkingGlass'),s("The","collection","of","all","glass","stemware",".","A","type","of","#$","Stemware","and","#$","DrinkingGlass",".","\"","Glass","stemware","\"","is","a","#$","SpatiallyDisjointObjectType","."),3032991). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tObjectStillCamera','tObjectDigitalCamera'),s("The","collection","of","all","digital","cameras",".","A","type","of","#$","DigitalCamera","and","#$","StillCamera",".","\"","Digital","camera","\"","is","a","#$","SpatiallyDisjointObjectType","."),3011187). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tPlaceLikeCommercialFacility','tPlaceLikeBuilding'),s("The","collection","of","all","commercial","buildings",".","A","type","of","#$","Building","and","#$","CommercialFacility","."),3032588). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tPlaceLikeElevatedRoadway','tPlaceLikeOverpass'),s("The","collection","of","all","overpass","roads",".","A","type","of","#$","ElevatedRoadway","and","#$","Overpass","."),3011595). assertion_content_comment(nartR('tColOfCollectionIntersection2Fn','tPlaceLikeManufacturingFacility','tGroupedHeavyIndustryFacility'),s("The","collection","of","all","manufacturing","plants",".","A","type","of","#$","ManufacturingFacility","and","#$","HeavyIndustryFacility","."),3011461). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['mobHeroicPerson','tClazzFemaleHuman'])),s("A","sub-collection","of","#$","Person",".","Each","instance","is","a","woman","possessing","heroic","qualities","or","a","woman","who","has","performed","heroic","deeds","."),1927159). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['mobHeroicPerson','tClazzMaleHuman'])),s("A","sub-collection","of","#$","Person",".","Each","instance","is","a","man","distinguished","by","exceptional","courage","and","nobility","and","strength","."),1927152). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['mobHeroicPerson','tClazzMaleHuman'])),s("The","collection","of","all","heroes",".","A","type","of","#$","HeroicPerson","and","#$","MaleHuman","."),3011356). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tAncient','tPlaceLikeRoadway'])),s("The","collection","of","all","ancient","roadways",".","A","type","of","#$","Ancient","and","#$","Roadway","."),3010972). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tClazzFemaleHuman','tClazzActor'])),s("A","sub-collection","of","#$","Person",".","Each","instance","is","a","female","actor","."),1922193). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tClazzFemaleHuman','tClazzActor'])),s("The","collection","of","all","actresses",",","who","are","actors","that","are","female",".","A","type","of","#$","FemaleHuman","and","#$","Actor","."),3010942). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tClazzMaleHuman','tClazzAristocrat'])),s("A","sub-collection","of","#$","Aristocrat",".","Each","instance","is","a","man","who","is","an","aristocrat","."),1926824). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tGroupedCommercialOrganization','tGroupedFarmTheOrganization'])),s("The","collection","of","all","commercial","farms",".","A","type","of","#$","FarmTheOrganization","and","#$","CommercialOrganization","."),3032785). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tGroupedEntertainmentOrRecreationOrganization','tGroupedServiceEstablishment'])),s("The","collection","of","all","entertainment","service","companies",".","A","type","of","#$","CommercialEntertainmentOrganization","and","#$","ServiceEstablishment","."),3011226). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tPlaceLikeBuilding','tHistoricalSite'])),s("The","collection","of","all","historic","buildings",".","A","type","of","#$","HistoricalSite","and","#$","Building","."),3011360). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tPlaceLikeBuiltUpArea','tHistoricalSite'])),s("The","collection","of","all","areas","with","historical","buildings","."),3010989). assertion_content_comment(nartR('tColOfCollectionIntersectionFn',uU('tSetOfTheSetFn',['tProduct','tNuclearRelatedThing'])),s("The","collection","of","all","nuclear","products",".","A","type","of","#$","NuclearRelatedThing","and","#$","Product","."),3011564). assertion_content_comment(nartR('tColOfCollectionSubsetFn','actCourseCollegiate',uU('tSetOfTheSetOfFn',COURSE,'exists'(SITE,'all'(SUB,'and'('isa'(SITE,'cwWorldWideWebSite'),'implies'('and'('isa'(SUB,'actEducation'),'subEvents'(COURSE,SUB)),'actors'(SUB,SITE))))))),s("The","collection","of","all","online","college","courses",".","A","type","of","#$","Course-Collegiate","."),3011579). assertion_content_comment(nartR('tColOfCollectionSubsetFn','mobPerson',uU('tSetOfTheSetOfFn',PERSON,'exists'(AGENCY,'and'('isa'(AGENCY,'tGroupedTaxAgency'),'positionOfPersonInOrganization'(PERSON,AGENCY,'mobCommissionerRank'))))),s("The","collection","of","all","tax","commissioners",".","A","#$","SpecifiedCollection","and","a","#$","SpatiallyDisjointObjectType","."),3011770). assertion_content_comment(nartR('tColOfCollectionSubsetFn','mobPerson',uU('tSetOfTheSetOfFn',X,'exists'(COUNTRY,'hasDissidentStatusIn'(X,COUNTRY)))),s("The","collection","of","all","people","who","are","dissidents",".","A","type","of","#$","HomoSapiens","."),3011190). assertion_content_comment(nartR('tColOfCollectionSubsetFn','tObjectFuelTank',uU('tSetOfTheSetOfFn',TANK,'and'('isa'(TANK,'tPlaceLikeFixedStructure'),'relationInstanceExists'('inContgeneric',TANK,'tGasolineFuel')))),s("The","collection","of","all","gasoline","reservoirs",".","A","type","of","#$","FuelTank","."),3011290). assertion_content_comment(nartR('tColOfCollectionSubsetFn','tPlaceLikeBarrierConstructionArtifact',uU('tSetOfTheSetOfFn',DRAGONTEETH,'exists'(BARRIERSITUATION,'exists'(PATH,'and'('isa'(PATH,'tPlaceLikePathForWheeledVehicles'),'barrier'(BARRIERSITUATION,DRAGONTEETH),'blockedPath'(BARRIERSITUATION,PATH)))))),s("The","collection","of","all","vehicle","barriers",".","A","type","of","#$","Barrier-ConstructionArtifact","."),3012108). assertion_content_comment(nartR('tColOfCollectionUnionFn',uU('tSetOfTheSetFn',[nartR('tPartTypeOrganismPartTypeFn','tClazzHomoSapiens','tPartTypeSkeletalSystem'),nartR('tColOfDeadPhysicalRemainsFn',nartR('tPartTypeOrganismPartTypeFn','tClazzHomoSapiens','tPartTypeSkeletalSystem'))])),s("The","collection","of","all","human","skeletons","."),3011394). assertion_content_comment(nartR('tColOfCompressedFn','tClazzGaseousTangibleThing'),s("The","collection","of","all","compressed","gas",".","A","type","of","#$","CompressedSubstance","and","#$","GaseousTangibleThing","."),3011144). assertion_content_comment(nartR('tColOfCrudeFn','tUranium'),s("Naturally","occurring","#$","Uranium","that","has","not","undergone","any","processing","or","preprocessing","to","turn","it","into","weapons-grade","material","or","nuclear","fuel","."),1422743). assertion_content_comment(nartR('tColOfDeadPhysicalRemainsFn','tClazzAnimal'),s("The","collection","of","all","carcasses",".","A","type","of","#$","DeadAnimal","."),3011085). assertion_content_comment(nartR('tColOfDeadPhysicalRemainsFn','tPartTypePlacenta'),s("The","collection","of","all","afterbirths",",","which","consist","of","the","remains","of","the","#$","Placenta","that","are","expelled","when","a","fetus","is","born",".","A","type","of","#$","InanimateObject-Natural","."),3010948). assertion_content_comment(nartR('tColOfDriedFn','tPartTypeSkin'),s("The","collection","of","all","dried","skin",".","A","type","of","#$","DriedProduct","."),3011199). assertion_content_comment(nartR('tColOfDrugProductFn','tKetorolac'),s("The","collection","of","all","Toradol",".","A","type","of","#$","AntiInflammatory","and","#$","Analgesic","."),3012075). assertion_content_comment(nartR('tColOfExtractedSampleFn','tPartTypeBlood'),s("The","collection","of","all","blood","samples",".","A","type","of","#$","ExtractedSample","and","#$","Blood","."),3011032). assertion_content_comment(nartR('tColOfExtractedSampleFn','tUrine'),s("The","collection","of","all","urine","samples",".","A","type","of","#$","Urine","and","#$","ExtractedSample","."),3012101). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iBaseballTheGame'),s("Fantasy","baseball",":","a","#$","FantasySportsGame","."),3011237). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iBasketballTheGame'),s("Fantasy","basketball",":","a","#$","FantasySportsGame","."),3011238). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iFootballAmerican'),s("Fantasy","football",":","a","#$","FantasySportsGame","."),3011239). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iGolf'),s("Fantasy","golf",":","a","#$","FantasySportsGame","."),3011240). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iIceHockey'),s("Fantasy","hockey",":","a","#$","FantasySportsGame","."),3011241). assertion_content_comment(nartR('tColOfFantasySportsGameOfFn','iSoccer'),s("Fantasy","soccer",":","a","#$","FantasySportsGame","."),3011242). assertion_content_comment(nartR('tColOfFoodOrDrinkForFn','mobNonPersonAnimal'),s("The","collection","of","all","feed",".","A","type","of","#$","FoodOrDrink","."),3011247). assertion_content_comment(nartR('tColOfFoodOrDrinkForFn','mobPetExotic'),s("The","collection","of","all","exotic","pet","food",".","A","type","of","#$","FoodOrDrink",".","\"","Exotic","pet","food","\"","is","an","#$","ExistingStuffType","."),3011233). assertion_content_comment(nartR('tColOfFoodServingFn','tObjectCoffeeBeverage'),s("The","collection","of","all","drinks","coffee",".","A","type","of","#$","Coffee-Beverage","and","#$","Food-ReadyToEat","."),3011135). assertion_content_comment(nartR('tColOfFreeThingOfTypeFn','cwComputerGameProgram'),s("The","collection","of","all","freeware","games",".","A","type","of","#$","ComputerGameProgram","and","#$","FreeThing","."),3011272). assertion_content_comment(nartR('tColOfFreeThingOfTypeFn','cwOnlineGameProgram'),s("The","collection","of","free","online","games","."),1075105). assertion_content_comment(nartR('tColOfFreeThingOfTypeFn','iboMusicalTextCopy'),s("The","collection","of","free","sheet","music","."),1077663). assertion_content_comment(nartR('tColOfGameteFn','tClazzAnimal'),s("The","collection","of","all","animal","gametes",".","A","type","of","#$","Gamete","."),3010977). assertion_content_comment(nartR('tColOfGameteFn','tClazzPlant'),s("The","collection","of","all","plant","gametes",".","A","type","of","#$","Gamete","."),3011619). assertion_content_comment(nartR('tColOfGaseousFn','tChlorine'),s("A","greenish-yellow",",","poisonous","gas","which","is","sometimes","used","as","a","chemical","weapon","."),1117235). assertion_content_comment(nartR('tColOfGaseousFn','tChloropicrin'),s("Poisonous","gas","which","has","effects","similar","to","tear","gas",".","If","ingested",",","the","gas","causes","gastroenteritis","."),1073618). assertion_content_comment(nartR('tColOfGaseousFn','tCholinesteraseInhibitingSubstance'),s("The","collection","of","all","nerve","gas",".","A","type","of","#$","ToxicGas","and","#$","CholinesteraseInhibitingSubstance","."),3011549). assertion_content_comment(nartR('tColOfGaseousFn','tCyanide'),s("The","collection","of","all","cyanide","gas",".","A","type","of","#$","Cyanide","and","#$","GaseousTangibleThing","."),3011168). assertion_content_comment(nartR('tColOfGaseousFn','tHydrogenCyanide'),s("The","collection","of","all","hydrogen","cyanide","gas",".","A","type","of","cyanide","gas","and","#$","HydrogenCyanide","."),3011398). assertion_content_comment(nartR('tColOfGaseousFn','tNitrogenMustard'),s("The","collection","of","all","nitrogen","mustard","gas",".","A","type","of","#$","NitrogenMustard","and","#$","GaseousTangibleThing","."),3011560). assertion_content_comment(nartR('tColOfGaseousFn','tPhosgene'),s("A","colorless",",","highly","poisonous","gas","."),1073988). assertion_content_comment(nartR('tColOfGaseousFn','tSarin'),s("The","collection","of","all","sarin","gas",".","A","type","of","#$","Sarin","and","nerve","gas","."),3011706). assertion_content_comment(nartR('tColOfGaseousFn','tTabun'),s("The","collection","of","all","tabun","gas",".","A","type","of","#$","Tabun","and","nerve","gas","."),3011767). assertion_content_comment(nartR('tColOfGaseousFn','tVENerveAgent'),s("The","collection","of","all","VE","gas",".","A","type","of","#$","VE-NerveAgent","and","nerve","gas","."),3012106). assertion_content_comment(nartR('tColOfGaseousFn','tVGNerveAgent'),s("The","collection","of","all","VG","nerve","gas",".","A","type","of","#$","VG-NerveAgent","and","nerve","gas","."),3012109). assertion_content_comment(nartR('tColOfGaseousFn','tVKNerveAgent'),s("The","collection","of","all","VK","gas",".","A","type","of","#$","VK-NerveAgent","and","nerve","gas","."),3012114). assertion_content_comment(nartR('tColOfGaseousFn','tVMNerveAgent'),s("The","collection","of","all","VM","nerve","gas",".","A","type","of","#$","VM-NerveAgent","and","nerve","gas.","."),3012115). assertion_content_comment(nartR('tColOfGaseousFn','tVXNerveAgent'),s("The","collection","of","all","VX","nerve","gas",".","A","type","of","#$","VX-NerveAgent","and","nerve","gas","."),3012118). assertion_content_comment(nartR('tColOfGaseousFn','tWater'),s("The","collection","of","all","water","vapor",".","A","type","of","#$","CleaningSubstance",",","#$","GaseousTangibleThing",",","and","#$","Water","."),3012125). assertion_content_comment(nartR('tColOfHideFn','tClazzAlligator'),s("The","collection","of","all","alligator","hides",".","A","type","of","#$","Hide-Product","."),3010959). assertion_content_comment(nartR('tColOfImitationOfCollectionFn','tObjectCurrency'),s("The","collection","of","all","counterfeit","currency",".","A","type","of","#$","HumanAccessibleIBO","."),3011157). assertion_content_comment(nartR('tColOfImitationOfCollectionFn','tObjectPassport'),s("The","collection","of","all","fake","passports",".","A","type","of","#$","CertificateDocument","."),3011236). assertion_content_comment(nartR('tColOfIsotopeFn','tHydrogen',2),s("A","specialization","of","#$","NuclearRelatedMaterial",",","known","as","\"","deuterium","\"","or","\"","H-2","\""),3096665). assertion_content_comment(nartR('tColOfIsotopeFn','tHydrogen',3),s("A","specialization","of","#$","NuclearRelatedMaterial",",","known","as","\"","tritium","\"","or","\"","H-3","\"","Tritium","is","an","essential","material","in","U.S",".","nuclear","weapons",".","It","is","an","isotope","of","#$","Hydrogen","that","decays","at","a","rate","of","about","five","percent","per","year","(","half","of","it","decays","in","about","12","years",")"),3096872). assertion_content_comment(nartR('tColOfIsotopeFn','tUranium',235),s("The","collection","of","pieces","of","#$","Uranium","whose","atoms","have","a","mass","number","of","235",".","Uranium-235","is","an","isotope","of","#$","Uranium",".","Uranium-235","is","often","used","in","nuclear","fission","reactions",".","It","is","the","only","naturally","occurring","fissile","isotope","(","see","#$","FissileMaterial",")"),1083209). assertion_content_comment(nartR('tColOfIsotopeFn','tUranium',238),s("The","collection","of","pieces","of","#$","Uranium","whose","atoms","have","a","mass","number","of","238",".","Uranium-238","is","an","isotope","of","#$","Uranium","."),1082858). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzAppleTree')),s("The","collection","of","all","apple","juice",".","A","type","of","#$","Juice",",","#$","Mixture",",","and","#$","SweetTaste","."),3010984). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzGrapefruitTree')),s("The","collection","of","all","grapefruit","juice",".","A","type","of","#$","Juice","."),3011334). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzGrapeVine')),s("The","collection","of","all","grape","juice",".","A","type","of","#$","Juice",",","#$","Mixture",",","and","#$","SweetTaste","."),3011332). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzLemonTree')),s("The","collection","of","all","lemon","juice",".","A","type","of","#$","Juice","."),3011442). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzLimeTree')),s("The","collection","of","all","lime","juice",".","A","type","of","#$","Juice","."),3011446). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzOrangeTree')),s("The","collection","of","all","orange","juice",".","A","type","of","#$","Juice","."),3011585). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzPineapplePlant')),s("The","collection","of","all","pineapple","juice",".","A","type","of","#$","Juice",",","#$","Mixture",",","and","#$","SweetTaste","."),3011617). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeFruitFn','tClazzTomatoPlant')),s("The","collection","of","all","tomato","juice",".","A","type","of","#$","Juice","and","#$","Mixture","."),3012073). assertion_content_comment(nartR('tColOfJuiceFn',nartR('tPartTypeRootFn','tClazzCarrotPlant')),s("The","collection","of","all","carrot","juice",".","A","type","of","#$","Juice","and","#$","Mixture","."),3011090). assertion_content_comment(nartR('tColOfJuiceFn','tCoconutMeat'),s("The","collection","of","all","coconut","milk",".","A","type","of","#$","Juice","and","#$","Mixture","."),3011134). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeFifthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1160021). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeFourthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1160169). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeSecondThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1159784). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeThirdThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1159826). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn','tPartTypeFemur'),s("Left","thigh","bones"),1063340). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn','tPartTypeFirstRib'),s("The","head","of","the","first","rib","on","the","left","side"),1085088). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn','tPartTypeMainBronchus'),s("This","NAT","is","VERY","EXTREMELY","weird","."),333274). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn','tPartTypeMainBronchus'),s("This","NAT","is","VERY","weird","."),333278). assertion_content_comment(nartR('tColOfLeftObjectOfPairFn','tPartTypeMainBronchus'),s("This","NAT","is","weird","."),1071418). assertion_content_comment(nartR('tColOfLiquidFn','tWaterSaline'),s("The","collection","of","all","saline","solution",".","A","type","of","#$","AqueousSolution",",","#$","LiquidTangibleThing",",","and","#$","Water-Saline","."),3011702). assertion_content_comment(nartR('tColOfMeatFn','tClazzCrab'),s("The","collection","of","all","crabmeat",".","A","type","of","shellfish","flesh.","."),3011160). assertion_content_comment(nartR('tColOfMeatFn','tClazzDeer'),s("The","collection","of","all","venison","(","deer","flesh",")","A","type","of","#$","Meat",".","\"","Deer","flesh","\"","is","an","#$","ExistingStuffType","."),3011174). assertion_content_comment(nartR('tColOfMeatFn','tClazzGooseBird'),s("The","collection","of","all","goose",".","A","type","of","#$","Meat","."),3011327). assertion_content_comment(nartR('tColOfParticleFn','tClazzLiquidTangibleThing'),s("The","collection","of","all","drops",".","A","type","of","#$","Particle","."),3011201). assertion_content_comment(nartR('tColOfParticleFn','tDew'),s("The","collection","of","all","dewdrops",".","A","type","of","#$","Particle","."),3011185). assertion_content_comment(nartR('tColOfParticleFn','tMatter'),s("The","collection","of","all","matter","particles",".","A","type","of","#$","Particle","."),3011469). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeEighthRib'),'tPartTypeBoneShaft'),"

",1159928). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeEighthRib'),'tPartTypeHeadOfBone'),"",1083667). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeEighthRib'),'tPartTypeTuberosity'),"",1076104). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeEleventhRib'),'tPartTypeHeadOfBone'),"",1078901). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFifthRib'),'tPartTypeBoneShaft'),"

",1160193). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFifthRib'),'tPartTypeHeadOfBone'),"",1071181). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFifthRib'),'tPartTypeTuberosity'),"",1071648). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeBoneShaft'),"

",1159886). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeHeadOfBone'),s("The","head","of","the","first","rib"),1085452). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeTuberosity'),"",1075725). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFourthRib'),'tPartTypeBoneShaft'),"

",1160267). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFourthRib'),'tPartTypeHeadOfBone'),"",1086188). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeFourthRib'),'tPartTypeTuberosity'),"",1073882). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeNinthRib'),'tPartTypeBoneShaft'),"

",1159714). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeNinthRib'),'tPartTypeHeadOfBone'),"",1087303). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeNinthRib'),'tPartTypeTuberosity'),"",1072743). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSecondRib'),'tPartTypeBoneShaft'),"

",1159904). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSecondRib'),'tPartTypeHeadOfBone'),s("The","head","of","the","second","rib","on","the","left","side"),1080314). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSecondRib'),'tPartTypeTuberosity'),"",1074604). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSeventhRib'),'tPartTypeBoneShaft'),"

",1159711). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSeventhRib'),'tPartTypeHeadOfBone'),"",1076389). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSeventhRib'),'tPartTypeTuberosity'),"",1088136). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSixthRib'),'tPartTypeBoneShaft'),"

",1160269). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSixthRib'),'tPartTypeHeadOfBone'),"",1077842). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeSixthRib'),'tPartTypeTuberosity'),"",1088506). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeTenthRib'),'tPartTypeBoneShaft'),"

",1160064). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeTenthRib'),'tPartTypeHeadOfBone'),"",1088410). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeTenthRib'),'tPartTypeTuberosity'),"",1074985). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeThirdRib'),'tPartTypeBoneShaft'),"

",1159960). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeThirdRib'),'tPartTypeHeadOfBone'),"",1079625). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeThirdRib'),'tPartTypeTuberosity'),"

",1159708). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfLeftObjectOfPairFn','tPartTypeTwelfthRib'),'tPartTypeHeadOfBone'),"",1082967). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeEighthRib'),'tPartTypeBoneShaft'),"

",1160061). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeEighthRib'),'tPartTypeTuberosity'),"",1073505). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFifthRib'),'tPartTypeBoneShaft'),"

",1159902). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFifthRib'),'tPartTypeTuberosity'),"",1070558). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeBoneShaft'),"",1085825). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeBoneShaft'),"

",1160034). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFirstRib'),'tPartTypeTuberosity'),"

",1159964). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFourthRib'),'tPartTypeBoneShaft'),"

",1160196). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeFourthRib'),'tPartTypeTuberosity'),"",1075353). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeNinthRib'),'tPartTypeBoneShaft'),"

",1160046). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeNinthRib'),'tPartTypeTuberosity'),"",1070190). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSecondRib'),'tPartTypeBoneShaft'),"

",1160242). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSecondRib'),'tPartTypeTuberosity'),"

",1159883). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSeventhRib'),'tPartTypeBoneShaft'),"

",1159718). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSeventhRib'),'tPartTypeTuberosity'),"",1072377). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSixthRib'),'tPartTypeBoneShaft'),"

",1160007). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeSixthRib'),'tPartTypeTuberosity'),"",1070918). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeTenthRib'),'tPartTypeBoneShaft'),"

",1160078). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeTenthRib'),'tPartTypeTuberosity'),"",1071270). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeThirdRib'),'tPartTypeBoneShaft'),"

",1159955). assertion_content_comment(nartR('tColOfPartTypeFn',nartR('tColOfRightObjectOfPairFn','tPartTypeThirdRib'),'tPartTypeTuberosity'),"",1073109). assertion_content_comment(nartR('tColOfPartTypeFn','tClazzProkaryoticCell','tPartTypeRibosome'),s("The","collection","of","all","prokaryotic","ribosomes",".","A","type","of","#$","Ribosome","."),3011652). assertion_content_comment(nartR('tColOfPornographyFn','actSexualBehavior'),s("The","collection","of","all","xxx","materials",".","A","type","of","#$","PornographicMaterial-Legal","."),3012140). assertion_content_comment(nartR('tColOfPornographyFn','mobHumanChild'),s("The","collection","of","all","child","pornography",".","A","type","of","#$","PornographicMaterial","."),3011114). assertion_content_comment(nartR('tColOfPornographyFn','mobHumanTeenager'),s("The","collection","of","all","teen","porn",".","A","type","of","#$","PornographicMaterial","."),3011777). assertion_content_comment(nartR('tColOfPornographyFn','tClazzHomosexualFemaleHuman'),s("The","collection","of","all","lesbian","pornography",".","A","type","of","#$","PornographicMaterial-Legal","."),3011443). assertion_content_comment(nartR('tColOfPornographyFn','tClazzHomosexualMaleHuman'),s("The","collection","of","all","gay","male","pornography",".","A","type","of","#$","PornographicMaterial-Legal","."),3011292). assertion_content_comment(nartR('tColOfPortableFn',nartR('tColOfDeadPhysicalRemainsFn','tPartTypeTreeBranch')),s("The","collection","of","all","sticks",".","A","type","of","#$","RigidPortableObject","and","#$","NotVeryRoundObject","."),3011753). assertion_content_comment(nartR('tColOfPortableFn','tObjectCalculator'),s("The","collection","of","all","portable","calculator",".","A","type","of","#$","PersonalDevice",",","#$","NotVeryRoundObject",",","and","#$","RigidPortableObject","."),3011635). assertion_content_comment(nartR('tColOfPortableFn','tObjectDigitalAudioRecorder'),s("A","type","of","#$","PersonalDevice",",","#$","NotVeryRoundObject",",","and","#$","RigidPortableObject","."),3011636). assertion_content_comment(nartR('tColOfPreviouslyOwnedFn','tObjectAutomobile'),s("The","collection","of","all","used","cars",".","A","type","of","#$","UsedArtifact","and","#$","Automobile","."),3012103). assertion_content_comment(nartR('tColOfProductByBrandFn','iSpeedoCommercialOrganization','tObjectSwimSuit'),s("The","collection","of","all","Speedo","swim","suits",".","A","type","of","#$","SwimSuit",".","Speedo","swim","suits","are","a","#$","ProductTypeByBrand","and","a","#$","SpatiallyDisjointObjectType","."),3011742). assertion_content_comment(nartR('tColOfProductFn','tClazzAnchovy'),s("The","collection","of","all","anchovy","products",".","A","type","of","#$","Anchovy","and","#$","Product","."),3010971). assertion_content_comment(nartR('tColOfProductFn','tInsecticide'),s("The","collection","of","all","insecticide","products",".","A","type","of","#$","Insecticide","and","#$","Product","."),3011414). assertion_content_comment(nartR('tColOfProductFn','tPesticide'),s("The","collection","of","all","pesticide","products",".","A","type","of","#$","Pesticide","."),3011610). assertion_content_comment(nartR('tColOfProductFn','tPetroleumCrudeOil'),s("The","collection","of","all","crude","petroleum","products",".","A","type","of","#$","Petroleum-CrudeOil","and","#$","PetroleumProduct","."),3011164). assertion_content_comment(nartR('tColOfProductFn','tPhosphorusTrichloride'),s("The","collection","of","all","phosphorus","trichloride","products",".","A","type","of","#$","PhosphorusTrichloride","and","#$","Product","."),3011612). assertion_content_comment(nartR('tColOfProductFn','tTrimethylPhosphite'),s("The","collection","of","all","trimethyl","phosphite","products",".","A","type","of","#$","TrimethylPhosphite","and","#$","Product","."),3012094). assertion_content_comment(nartR('tColOfPureFn','tAmmonia'),s("The","collection","of","all","anhydrous","ammonia",".","A","type","of","#$","Ammonia","and","#$","PureSubstance","."),3010975). assertion_content_comment(nartR('tColOfRefinedFn','tNaturalGas'),s("A","type","of","#$","Product","."),3011676). assertion_content_comment(nartR('tColOfRefinedFn','tOil'),s("The","collection","of","all","refined","petroleum","products",".","A","type","of","#$","Product","."),3011677). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeEighthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1072287). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeFifthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1073018). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeFirstThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1159950). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeFourthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1073414). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeNinthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1077123). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeSecondThoracicVertebra','tPartTypeVertebralTransverseProcess')),"

",1159951). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeSeventhThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1073792). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeSixthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1074171). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeTenthThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1078542). assertion_content_comment(nartR('tColOfRightObjectOfPairFn',nartR('tColOfPartTypeFn','tPartTypeThirdThoracicVertebra','tPartTypeVertebralTransverseProcess')),"",1071553). assertion_content_comment(nartR('tColOfSolidFn','tObjectConcrete'),s("The","collection","of","all","cement",".","A","type","of","#$","Concrete","and","#$","ObjectSturdyWRTHumanActivity","."),3011098). assertion_content_comment(nartR('tColOfSolidFn','tObjectPlastic'),s("The","collection","of","all","solid","plastics",".","A","type","of","#$","Plastic",",","#$","SolidTangibleArtifact",",","and","#$","Flexible","."),3011739). assertion_content_comment(nartR('tColOfSolidFn','tSaltNaCl'),s("Solid",",","crystalline","sodium","chloride","."),1055078). assertion_content_comment(nartR('tColOfSolidFn','tWater'),s("The","collection","of","all","ice",".","A","type","of","#$","BulkState",",","#$","Water",",","and","#$","MacroCrystalline","."),3011401). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tAmmonia'),s("The","collection","of","all","ammonia","solution",".","A","type","of","#$","AqueousSolution","and","#$","LiquidTangibleThing","."),3010968). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tHydrogenChloride'),s("The","collection","of","all","hydrochloric","acid","solution",".","A","type","of","#$","AqueousSolution","and","#$","ToxicSubstance","."),3011396). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tNitricAcid'),s("The","collection","of","all","nitric","acid","solution",".","A","type","of","#$","AqueousSolution","."),3011559). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tSaltNaCl'),s("The","collection","of","all","salt","water",".","A","type","of","#$","AqueousSolution",".","\"","Salt","water","\"","is","an","#$","ExistingStuffType","."),3011704). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tSodiumHydroxide'),s("The","collection","of","all","sodium","hydroxide","solution",".","A","type","of","#$","AqueousSolution",".","Sodium","hydroxide","solution","is","#$","TangibleStuffCompositionType","."),3011736). assertion_content_comment(nartR('tColOfSolutionFn',nartR('tColOfLiquidFn','tWater'),'tSulfuricAcid'),s("The","collection","of","all","sulfuric","acid","solution",".","A","type","of","#$","AcidicSolution-Liquid","and","#$","AqueousSolution",".","Sulfuric","acid","solution","is","#$","TangibleStuffCompositionType","."),3011762). assertion_content_comment(nartR('tColOfSportsFranchiseTypeBySportFn','iBasketballTheGame'),s("The","collection","of","all","basketball","franchises",".","A","type","of","#$","SportsFranchise","."),3011014). assertion_content_comment(nartR('tColOfStuffFn',nartR('tPartTypeLeafFn','tClazzTeaPlant')),s("The","collection","of","all","tea",".","A","type","of","#$","BiologicalLivingObject","."),3011772). assertion_content_comment(nartR('tColOfStuffFn','tClazzSmallpoxVirus'),s("The","collection","of","all","smallpox","viruses",".","A","type","of","#$","ViralBioAgent","."),3011729). assertion_content_comment(nartR('tColOfStuffFn','tPancake'),s("The","collection","of","all","flapjacks",".","A","type","of","#$","BreakfastFood",",","#$","SemiSolidTangibleThing",",","and","#$","CerealFood","."),3011252). assertion_content_comment(nartR('tColOfStuffFn','tPartTypeOnionBulb'),s("The","collection","of","all","onion","bulb","stuff",".","A","type","of","#$","Onion-Foodstuff","and","#$","BiologicalLivingObject","."),3033048). assertion_content_comment(nartR('tColOfStuffFn','tPartTypePistachioTheNut'),s("The","collection","of","all","pistachio",".","A","type","of","#$","KosherFood","and","#$","BiologicalLivingObject.","."),3011618). assertion_content_comment(nartR('tColOfSubcollectionOfAboutFn','cwManagedAccount','cwCommoditiesFuture'),s("the","#$","relationExistsAll","assertion","on","this","constant","is","only","true","if","all","company","that","sell/market","these","accounts","are","defined","as","#$","CommodityBrokerageFirms","."),559052). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationFromFn',uU('tColOfSpecsFn','tObjectAudioVideoEquipment'),'locationTypeTypicallyContainsType','tPartTypeConferenceRoom'),s("The","subcollection","of","AV","equipment","that","you","would","typically","find","in","conference","rooms","."),3751369). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationFromTypeFn','tGroupedOrganization','subOrganizations','tGroupedOrganization'),s("A","sub-collection","of","#$","Organization",".","Each","instance","is","an","organization","regarded","as","part","of","a","larger","social","group","."),1919964). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationFromTypeFn','vtTimeQuantity','duration','tTemporalThing'),s("A","sub-collection","of","#$","Time-Quantity",".","Each","instance","is","the","period","of","time","during","which","something","continues","."),1922011). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToFn','actStentPlacement','objectActedOnType','tPartTypeCommonCarotidArtery'),s("the","placement","of","a","stent","into","the","carotid","artery"),2986411). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToFn','actStentPlacement','objectActedOnType','tPartTypeCoronaryArtery'),s("placement","of","a","stent","inside","one","of","the","the","patient","'","s","coronary","arteries","."),2986426). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToTypeFn','actGiftGiving','objectOfPossessionTransfer','tObjectCurrency'),s("This","non-atomic","reified","term","denotes","the","sub-collection","of","#$","GiftGiving","events","in","which","the","#$","objectOfPossessionTransfer","is","currency","."),1110534). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToTypeFn','actLoadingAProjectileWeapon','toLocation','tObjectMissile'),s("The","collection","of","all","events","in","which","|","|","a","#$","MissileLauncher","is","loaded","."),1078457). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToTypeFn','eventCreationEvent','outputsCreated','tGroupedCommunity'),s("A","collection","of","events",";","a","subcollection","of","#$","CreationEvent",".","In","each","(","#$","SubcollectionOfWithRelationToTypeFn","#$","CreationEvent","#$","outputsCreated","#$","Community",")",",","someone","forms","a","community","."),1915829). assertion_content_comment(nartR('tColOfSubcollectionOfWithRelationToTypeFn','tVisualImage','imageDepicts',nartR('tColOfSubcollectionOfWithRelationFromTypeFn','tBackSide','physicalParts','tSpatialThing')),s("The","collection","of","views","of","back","sides","of","#$","SpatialThings","."),5021271). assertion_content_comment(nartR('tColOfTasteFn',nartR('tPartTypeFruitFn','tClazzBananaTree')),s("The","collection","of","all","things","that","taste","like","bananas",".","An","#$","ObjectTypeByTaste","."),3011254). assertion_content_comment(nartR('tColOfTransportLayerProtocolFn','iTransmissionControlProtocol'),s("The","collection","of","all","TCP","packets",".","A","type","of","#$","Packet-Internet","."),3011771). assertion_content_comment(nartR('tColOfUnitOperationsOfTypeFn','actModificationProcessSingleWafer'),s("The","collection","of","all","instances","of","#$","ModificationProcess-SingleWafer","wherein","a","complete","'","recipe","'","for","modifying","a","#$","SemiconductorWafer","instance","or","selected","portion","thereof","is","carried","out","end-to-end","(","to","designed","completion",")","as","an","instantiation","of","a","specified","stage","in","a","specified","semiconductor","manufacturing","process","thread","."),4468218). assertion_content_comment(nartR('tColOfUnitOperationsOfTypeFn','actPhotoresistStrippingProcessSingleWafer'),s("The","collection","of","all","events","wherein","a","previously","deposited","and","developed","photoresist","template","is","completely","removed","(","within","acceptable","margins","of","error",")","from","a","#$","SemiconductorWafer","instance","using","physical","or","chemical","means",",","as","an","instantiation","of","a","designed","stage","within","an","instantiation","of","a","process","thread","specification","that","includes","the","stage","."),4466444). assertion_content_comment(nartR('tColOfUnitOperationsOfTypeFn','actRemovalProcessSingleWafer'),s("The","collection","of","all","instances","of","#$","RemovalProcess-SingleWafer","that","are","self-contained","unit","operations","#$","ManufacturingProcessUnitOperation","within","instantiations","of","#$","SemiconductorWafer","manufacturing","process","threads",".","'","Self","contained","'","here","means",",","among","other","things",",","that","all","and","only","the","entirety","of","the","#$","ThinFilm","that","the","process","thread","specification","indicates","*","should","*","be","removed","from","the","wafer","for","the","process","'","step","'","*","is","*","removed","from","the","wafer","by","the","end","of","the","(","#$","UnitOperationsOfTypeFn","#$","RemovalProcess-SingleWafer",")","instance",",","within","acceptable","margins","of","error","."),4466439). assertion_content_comment(nartR('tColOfUnitOperationsOfTypeFn','actWaferEtchingProcessSingleWafer'),s("The","collection","of","all","events","wherein","selected","portions","of","a","#$","ThinFilm","that","is","not","an","instance","of","#$","ResistLayer","are","completely","removed","(","to","within","acceptable","fault","tolerances","or","margins","of","error",")","by","exposure","to","either","an","acid","solvent","or","ion","plasma","."),4466464). assertion_content_comment(nartR('tColOfVaccineForFn','eventSmallpoxInfection'),s("The","collection","of","all","variola","vaccine",".","A","type","of","#$","Vaccine",".","(","#$","VaccineForFn","#$","SmallpoxInfection",")","is","a","#$","PharmaceuticalType","."),3012105). assertion_content_comment(nartR('tColOfVaccineForFn','stateAnthraxInfection'),s("The","collection","of","all","anthrax","vaccines",".","A","type","of","#$","Vaccine","."),3010980). assertion_content_comment(nartR('tColOfVaccineForFn','stateChickenPox'),s("The","collection","of","all","chicken","pox","vaccine",".","A","type","of","#$","Vaccine","."),3011112). assertion_content_comment(nartR('tColOfVaccineForFn','stateDiphtheria'),s("The","collection","of","all","Diphtheria","vaccine",".","A","type","of","#$","Vaccine","."),3011189). assertion_content_comment(nartR('tColOfVaccineForFn','stateHepatitisBInfection'),s("The","collection","of","all","hepatitis","B","infection","vaccine",".","A","type","of","#$","Vaccine","."),3011353). assertion_content_comment(nartR('tColOfVaccineForFn','stateLymeDisease'),s("The","collection","of","all","Lyme","disease","vaccine",".","A","type","of","#$","Vaccine",".","(","#$","VaccineForFn","#$","LymeDisease",")","is","a","#$","PharmaceuticalType","."),3011452). assertion_content_comment(nartR('tColOfVaccineForFn','stateMeasles'),s("The","collection","of","all","measles","vaccine",".","A","type","of","#$","Vaccine",".","(","#$","VaccineForFn","#$","Measles",")","is","a","#$","PharmaceuticalType","."),3011470). assertion_content_comment(nartR('tColOfVaccineForFn','stateMumps'),s("The","collection","of","all","mumps","vaccine",".","A","type","of","#$","Vaccine","."),3011541). assertion_content_comment(nartR('tColOfVaccineForFn','stateRabies'),s("The","collection","of","all","rabies","vaccine",".","A","type","of","#$","Vaccine","."),3011662). assertion_content_comment(nartR('tColOfVaccineForFn','stateRubella'),s("The","collection","of","all","rubella","vaccine",".","A","type","of","#$","Vaccine","."),3011696). assertion_content_comment(nartR('tColOfVaccineForFn','stateTetanus'),s("The","collection","of","all","tetanus","vaccine",".","A","type","of","#$","Vaccine",".","(","#$","VaccineForFn","#$","Tetanus",")","is","a","#$","PharmaceuticalType","."),3011783). assertion_content_comment(nartR('tColOfWildPlantBLOFn',nartR('tPartTypeFruitFn','tClazzCherryTree')),s("The","collection","of","all","wild","cherries",".","A","type","of","cherry","."),3012132). assertion_content_comment(nartR('tColOfWoodFn','tClazzAlderTree'),s("The","collection","of","all","alder","tree","wood",".","A","type","of","#$","Wood",".","\"","(","#$","WoodFn","#$","AlderTree",")","\"","is","an","#$","ExistingStuffType","."),3010958). assertion_content_comment(nartR('tColOfWoodFn','tClazzAppleTree'),s("The","collection","of","all","apple","tree","wood",".","A","type","of","#$","Wood","."),3010985). assertion_content_comment(nartR('tColOfWoodFn','tClazzAshTree'),s("The","collection","of","all","wood","of","ash","trees",".","A","type","of","#$","Wood","."),3010992). assertion_content_comment(nartR('tColOfWoodFn','tClazzBirch'),s("The","collection","of","all","birch","tree","wood",".","A","type","of","#$","Wood","."),3011030). assertion_content_comment(nartR('tColOfWoodFn','tClazzCedarTree'),s("The","collection","of","all","cedarwood",".","A","type","of","#$","Wood","."),3011094). assertion_content_comment(nartR('tColOfWoodFn','tClazzCherryTree'),s("The","collection","of","all","cherry","tree","wood",".","A","type","of","#$","Wood","."),3011108). assertion_content_comment(nartR('tColOfWoodFn','tClazzDogwood'),s("The","collection","of","all","dogwood","tree","wood",".","A","type","of","#$","Wood","."),3011195). assertion_content_comment(nartR('tColOfWoodFn','tClazzElmTree'),s("The","collection","of","all","elm","tree","wood",".","A","type","of","#$","Wood",".","\"","Elm","\"","is","an","#$","ExistingStuffType","."),3011222). assertion_content_comment(nartR('tColOfWoodFn','tClazzHickoryTree'),s("The","collection","of","all","hickory","tree","wood",".","A","type","of","#$","Wood","."),3011357). assertion_content_comment(nartR('tColOfWoodFn','tClazzLindenTree'),s("The","collection","of","all","basswood","(","wood","of","linden","trees",")","A","type","of","#$","Wood","."),3011019). assertion_content_comment(nartR('tColOfWoodFn','tClazzMahoganyTree'),s("The","collection","of","all","mahogany",".","A","type","of","#$","Wood",".","\"","Mahogany","\"","is","an","#$","ExistingStuffType","."),3011456). assertion_content_comment(nartR('tColOfWoodFn','tClazzMapleTree'),s("The","collection","of","all","maple","wood",".","A","type","of","#$","Wood","."),3011463). assertion_content_comment(nartR('tColOfWoodFn','tClazzOakTree'),s("The","collection","of","all","wood","of","oak","trees",".","A","type","of","#$","Wood","."),3011570). assertion_content_comment(nartR('tColOfWoodFn','tClazzPineTree'),s("The","collection","of","all","true","pine",".","A","type","of","#$","Wood",".","\"","True","pine","\"","is","an","#$","ExistingStuffType","."),3012095). assertion_content_comment(nartR('tColOfWoodFn','tClazzPoplar'),s("The","collection","of","all","poplar","tree","wood",".","A","type","of","#$","Wood",".","\"","(","#$","WoodFn","#$","Poplar",")","\"","is","an","#$","ExistingStuffType","."),3011631). assertion_content_comment(nartR('tColOfWoodFn','tClazzRedwoodTree'),s("The","collection","of","all","redwood",".","A","type","of","#$","Wood",".","\"","Redwood","\"","is","an","#$","ExistingStuffType","."),3011675). assertion_content_comment(nartR('tColOfWoodFn','tClazzSandalwoodTree'),s("The","collection","of","all","sandalwood","tree","wood",".","A","type","of","#$","Wood","."),3011705). assertion_content_comment(nartR('tGroupedClubRelatedFn','actInvesting'),s("The","collection","of","all","investment","clubs",".","A","type","of","#$","Club-Organization","."),3011421). assertion_content_comment(nartR('tGroupedClubRelatedFn','tObjectPorscheCar'),s("The","collection","of","Porsche","car","clubs","."),1070806). assertion_content_comment(nartR('tGroupedGroupFn','cwPoemCW'),s("The","collection","of","all","poetry",".","A","type","of","#$","LiteraryWork-CW","."),3011626). assertion_content_comment(nartR('tGroupedGroupFn','mobInsurgent'),s("The","collection","of","all","insurgents","group",".","A","type","of","group","of","humans","."),3011415). assertion_content_comment(nartR('tGroupedGroupFn','mobMilitant'),s("The","collection","of","all","militant","groups",".","A","type","of","group","of","extremists","."),3011506). assertion_content_comment(nartR('tGroupedGroupFn','mobPerson'),s("The","collection","of","all","groups","of","people",".","More","precisely",",","this","is","the","collection","of","each","instance","of","#$","Group","such","that","each","member","of","that","instance","(","see","#$","groupMembers",")","is","an","instance","of","#$","Person","."),1079960). assertion_content_comment(nartR('tGroupedGroupFn','tClazzAssassin'),s("A","sub-collection","of","#$","Team-Generic",".","Each","instance","is","a","team","of","assassins","."),1927874). assertion_content_comment(nartR('tGroupedGroupFn','tClazzAssassin'),s("The","collection","of","all","hit","squads",".","A","type","of","#$","Team","."),3011380). assertion_content_comment(nartR('tGroupedGroupFn','tGroupedHockeyTeam'),s("The","collection","of","all","hockey","leagues",".","A","type","of","group","of","sports","teams","."),3011383). assertion_content_comment(nartR('tGroupedGroupFn','tGroupedMilitaryOrganization'),s("This","is","the","#$","Collection","of","all","#$","Groups","of","instances","of","#$","MilitaryOrganization",".","Since","#$","MilitaryOrganization","is","a","collection","of","groups",",","this","collection","is","itself","a","collection","of","groups","of","groups","."),1081164). assertion_content_comment(nartR('tGroupedGroupFn','tGroupedProfessionalSportsTeam'),s("The","collection","of","all","professional","sports","leagues",".","A","type","of","group","of","sports","teams","."),3011642). assertion_content_comment(nartR('tGroupedGroupFn','tObjectCookingVessel'),s("The","collection","of","all","cookware","sets",".","A","type","of","group","of","inanimate","objects","."),3011151). assertion_content_comment(nartR('tGroupedGroupFn','tObjectOfficeFurniture'),s("The","collection","of","all","office","furniture","suites",".","A","type","of","group","of","furniture","."),3011574). assertion_content_comment(nartR('tGroupedGroupFn','tObjectProjectileShellAssembly'),s("The","collection","of","all","ammunition",".","A","type","of","group","of","devices","."),3010969). assertion_content_comment(nartR('tGroupedGroupFn','tObjectSilverwarePiece'),s("The","collection","of","all","flatware","sets",".","A","type","of","group","of","devices","."),3011253). assertion_content_comment(nartR('tGroupedGroupFn','tObjectTransportationDeviceVehicle'),s("The","collection","of","all","fleets",".","A","type","of","group","of","transportation","devices","."),3011257). assertion_content_comment(nartR('tGroupedIndependentMoleculeFn','iboDNAPolymer'),s("The","collection","of","all","DNA","molecules",".","A","type","of","#$","DNAPolymer","."),3011192). assertion_content_comment(nartR('tGroupedIndependentMoleculeFn','tPolymerMolecule'),s("The","collection","of","all","polymer","molecules",".","A","type","of","#$","PolymerMolecule","."),3011629). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectAgriculturalImplement'),s("The","collection","of","all","agricultural","implement","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011243). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectAirConditioner'),s("The","collection","of","all","air","conditioner","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3010953). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectAirplane'),s("The","collection","of","all","plane","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011460). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectClothingGeneric'),s("The","collection","of","all","clothing","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011126). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectComputer'),s("The","collection","of","all","computer","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011147). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectDVDDisk'),s("The","collection","of","all","DVD","disc","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011207). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectElectricalDevice'),s("The","collection","of","all","electrical","device","manufacturers",".","A","type","of","#$","ManufacturingCompany",".","\"","(","#$","ManufacturerFn","#$","ElectricalDevice",")","\"","is","a","#$","FacetInstanceCollection","."),3011220). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectElectronicDevice'),s("The","collection","of","all","manufacturers","of","electronics",".","A","type","of","#$","ManufacturingCompany","."),3011459). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectGolfClub'),s("The","collection","of","all","golf","club","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011325). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectHydroPoweredTurbine'),s("The","collection","of","all","hydroelectric","turbine","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011397). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectIntegratedCircuit'),s("The","collection","of","all","computer","chip","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011145). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectLingerie'),s("The","collection","of","all","lingerie","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011447). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectMachineTool'),s("The","collection","of","all","machine","tool","manufacturers",".","A","type","of","#$","ManufacturingCompany",".","\"","(","#$","ManufacturerFn","#$","MachineTool",")","\"","is","a","#$","FacetInstanceCollection","."),3011454). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectMicrowaveOven'),s("The","collection","of","all","microwave","oven","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011503). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectMotorcycle'),s("The","collection","of","all","motorcycle","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011537). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectRefrigerator'),s("The","collection","of","all","refrigerator","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011678). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectSteel'),s("The","collection","of","all","steel","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011752). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectSubmarine'),s("The","collection","of","all","submarine","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011759). assertion_content_comment(nartR('tGroupedManufacturerFn','tObjectTelevisionSet'),s("The","collection","of","all","television","set","manufacturer",".","A","type","of","#$","ManufacturingCompany","."),3011779). assertion_content_comment(nartR('tGroupedManufacturerFn','tPartTypeAutoPart'),s("The","collection","of","all","auto","part","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3010996). assertion_content_comment(nartR('tGroupedManufacturerFn','tPartTypeComputerMonitorVideoKind'),s("The","collection","of","all","monitor","manufacturers",".","A","type","of","#$","ManufacturingCompany","."),3011534). assertion_content_comment(nartR('tGroupedManufacturerFn','tPartTypeElectronicComponent'),s("The","collection","of","all","manufacturers","of","electronic","components",".","A","type","of","manufacturer","of","electronics","."),3011458). assertion_content_comment(nartR('tGroupedMobFn','iboInformationBearingObject'),s("The","collection","of","all","archives",".","A","type","of","#$","Mob","."),3010988). assertion_content_comment(nartR('tGroupedMobFn','tDustParticle'),s("The","collection","of","all","dust",".","A","type","of","#$","Mob","."),3011205). assertion_content_comment(nartR('tGroupedMobFn','tNuclearFalloutParticle'),s("The","collection","of","all","nuclear","fallout",".","A","type","of","#$","Mob","."),3011562). assertion_content_comment(nartR('tGroupedMobFn','tObjectRVBalloon'),s("A","commonly-deployed","#$","BallisticMissileCountermeasureType",",","deployed","to","mask","the","primary","reentry","vehicle","or","vehicles","from","ground-based","radar","."),5008553). assertion_content_comment(nartR('tGroupedMobFn','tPartTypeLeaf'),s("The","collection","of","all","foliage",".","A","type","of","#$","Mob","."),3011262). assertion_content_comment(nartR('tGroupedMobFn','tPartTypeRiceSingleGrain'),s("The","collection","of","all","rice",".","A","type","of","#$","MexicanCuisine","and","#$","Mob","."),3011688). assertion_content_comment(nartR('tGroupedMoleculeFn','tBromine'),s("The","collection","of","all","bromine","molecules",".","A","type","of","#$","Molecule","."),3011073). assertion_content_comment(nartR('tGroupedMoleculeFn','tCarbonDioxide'),s("The","collection","of","all","carbon","dioxide","molecules",".","A","type","of","#$","Molecule","."),3011084). assertion_content_comment(nartR('tGroupedMoleculeFn','tChlorine'),s("The","collection","of","all","chlorine","molecules",".","A","type","of","#$","Molecule","."),3011116). assertion_content_comment(nartR('tGroupedMoleculeFn','tEthane'),s("The","collection","of","all","ethane","molecules",".","A","type","of","#$","AlkaneMolecule","."),3011230). assertion_content_comment(nartR('tGroupedMoleculeFn','tHydrogen'),s("The","collection","of","all","hydrogen","molecules",".","A","type","of","(","#$","AtomGroupingFn","#$","Hydrogen","2",")","and","#$","Molecule","."),3011399). assertion_content_comment(nartR('tGroupedMoleculeFn','tInorganicCompound'),s("The","collection","of","all","inorganic","molecules",".","A","type","of","#$","Molecule","."),3011412). assertion_content_comment(nartR('tGroupedMoleculeFn','tIodine'),s("The","collection","of","all","iodine","molecules",".","A","type","of","#$","Molecule",".","\"","(","#$","MoleculeFn","#$","Iodine",")","\"","is","a","#$","MoleculeTypeByChemicalCompoundType","."),3011423). assertion_content_comment(nartR('tGroupedMoleculeFn','tLipid'),s("The","collection","of","all","lipid","molecules",".","A","type","of","#$","Molecule",".","\"","Lipid","molecule","\"","is","a","#$","MoleculeTypeByChemicalCompoundType","."),3011449). assertion_content_comment(nartR('tGroupedMoleculeFn','tOzone'),s("The","collection","of","all","ozone","molecules",".","A","type","of","(","#$","AtomGroupingFn","#$","Oxygen","3",")","and","#$","Molecule","."),3011596). assertion_content_comment(nartR('tGroupedMoleculeFn','tPropane'),s("The","collection","of","all","propane","molecules",".","A","type","of","#$","HydrocarbonMolecule","."),3011653). assertion_content_comment(nartR('tGroupedMoleculeFn','tProteinStuff'),s("The","collection","of","all","protein","molecules",".","A","type","of","#$","Molecule","."),3011654). assertion_content_comment(nartR('tGroupedMoleculeFn','tSugar'),s("The","collection","of","all","sugar","molecules",".","A","type","of","#$","Molecule","."),3011760). assertion_content_comment(nartR('tGroupedMoleculeFn','tWater'),s("The","collection","of","all","water","molecules",".","A","type","of","#$","Molecule","."),3012124). assertion_content_comment(nartR('tGroupedOrgRelatedFn','actAgriculture'),s("The","collection","of","all","agricultural","organizations",".","A","type","of","#$","Organization","."),3010949). assertion_content_comment(nartR('tGroupedOrgRelatedFn','actBoxingSportsEvent'),s("The","collection","of","all","boxing","organizations",".","A","type","of","#$","Organization","."),3011047). assertion_content_comment(nartR('tGroupedOrgRelatedFn','iScience'),s("The","collection","of","all","scientific","organizations",".","A","type","of","#$","Organization","."),3011709). assertion_content_comment(nartR('tGroupedProductionIndustryTypeFn','actAgriculture'),s("The","collection","of","all","agriculture","industry",".","A","type","of","#$","Industry-Localized","."),3010951). assertion_content_comment(nartR('tGroupedProductionIndustryTypeFn','tNaturalGas'),s("The","collection","of","all","natural","gas","industry",".","A","type","of","#$","Industry-Localized","."),3011543). assertion_content_comment(nartR('tGroupedProductionIndustryTypeFn','tObjectDefenseSystem'),s("The","collection","of","all","defense","system","industry",".","A","type","of","#$","Industry-Localized","."),3011175). assertion_content_comment(nartR('tGroupedProductionIndustryTypeFn','tTourism'),s("The","collection","of","all","tourism","industry",".","A","type","of","#$","Industry-Localized","."),3012076). assertion_content_comment(nartR('tGroupedRestaurantSpecializingInCuisineFn','tObjectAmericanStyleFastFoodCuisine'),s("The","collection","of","all","fast","food","restaurants",".","A","type","of","#$","RestaurantOrg-WithoutWaitstaff","."),3011245). assertion_content_comment(nartR('tGroupedStoreFn','tObjectWeapon'),s("The","collection","of","all","arms","caches",".","A","type","of","#$","Store-Generic","."),3010990). assertion_content_comment(nartR('tGroupedSurvivorSupportGroupFn','actMurder'),s("The","collection","of","all","survivor","support","|","|","groups","for","people","who","have","been","affected","by","|","|","a","murder",".","Candidates","for","inclusion","in","|","|","such","groups","include","neighbors",",","friends",",","and","|","|","family","members","of","murder","victims",",","but","obviously","|","|","exclude","murder","victims","."),1086788). assertion_content_comment(nartR('tGroupedSurvivorSupportGroupFn','actSuicide'),s("This","is","the","collection","of","all","support","|","|","groups","for","people","whose","lives","have","been","|","|","impacted","by","suicide",".","Candidates","for","membership","|","|","in","such","groups","include","family","members",",","friends",",","|","|","neighbors",",","etc",".","of","suicide","victims",",","but","obviously","|","|","not","suicide","victims","."),1087158). assertion_content_comment(nartR('tGroupedWrittenCharacterFn','iLatinCapitalLetterL'),s("A","type","of","#$","WrittenCharacter","."),3012138). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectAudioEquipment'),s("The","collection","of","all","audio","accessories",".","A","type","of","#$","Artifact","."),3010995). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectBedPieceOfFurniture'),s("The","collection","of","all","bed","accessories",".","A","type","of","#$","Artifact","."),3011023). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectBicycle'),s("The","collection","of","all","bicycle","accessories",".","A","type","of","#$","Artifact","."),3011027). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectDeskPieceOfFurniture'),s("The","collection","of","all","desk","accessories",".","A","type","of","#$","Artifact","."),3011181). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectGrillIndoor'),s("The","collection","of","all","indoor","grill","products",".","A","type","of","#$","Artifact","."),3011407). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectMotorcycle'),s("The","collection","of","all","motorcycle","accessories",".","A","type","of","#$","Artifact","."),3011536). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectSmokingDevice'),s("The","collection","of","all","smoking","accessories",".","A","type","of","#$","Artifact","."),3011731). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectTelephone'),s("The","collection","of","all","telephone","accessories",".","A","type","of","#$","Artifact","."),3011778). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tObjectWirelessCommunicationDevice'),s("The","collection","of","all","accessories","for","wireless","communications","devices",".","A","type","of","#$","Artifact","."),3012136). assertion_content_comment(nartR('tObjectAccessoryFnArtifact','tPartTypeFireplace'),s("The","collection","of","all","fireplace","accessories",".","A","type","of","#$","Artifact","."),3011250). assertion_content_comment(nartR('tObjectAntiWeaponTypeFn','tObjectTankVehicle'),s("The","collection","of","all","anti-tank","weapons",".","A","type","of","#$","Artifact","."),3010982). assertion_content_comment(nartR('tObjectBottledProductFn','tGroupedSandMob'),s("The","collection","of","all","bottled","sand",".","A","type","of","#$","BottledProduct","."),3011042). assertion_content_comment(nartR('tObjectBottledProductFn','tJuice'),s("The","collection","of","all","bottled","juice",".","A","type","of","#$","BottledProduct","."),3011040). assertion_content_comment(nartR('tObjectBottledProductFn','tObjectAlcoholicBeverage'),s("The","collection","of","all","bottled","alcoholic","beverage",".","A","type","of","#$","BottledProduct","."),3011038). assertion_content_comment(nartR('tObjectBottledProductFn','tObjectBeer'),s("The","collection","of","all","bottled","beer",".","A","type","of","#$","BottledProduct","."),3011039). assertion_content_comment(nartR('tObjectBottledProductFn','tObjectCowsMilkProduct'),s("The","collection","of","all","bottled","milk",".","A","type","of","#$","BottledProduct","."),3011041). assertion_content_comment(nartR('tObjectChemicalWeaponFn',nartR('tColOfGaseousFn','tCholinesteraseInhibitingSubstance')),s("The","collection","of","all","nerve","gas","weapons",".","A","type","of","nerve","agent","weapon","."),3011550). assertion_content_comment(nartR('tObjectChemicalWeaponFn','tCholinesteraseInhibitingSubstance'),s("The","collection","of","all","nerve","agent","weapons",".","A","type","of","#$","ChemicalWeapon","."),3011548). assertion_content_comment(nartR('tObjectChemicalWeaponFn','tTabun'),s("The","collection","of","all","tabun","weapons",".","A","type","of","nerve","agent","weapon","."),3011768). assertion_content_comment(nartR('tObjectChemicalWeaponFn','tVENerveAgent'),s("The","collection","of","all","VE","weapons",".","A","type","of","nerve","agent","weapon","."),3012107). assertion_content_comment(nartR('tObjectChemicalWeaponFn','tVXNerveAgent'),s("The","collection","of","all","VX","weapons",".","A","type","of","nerve","agent","weapon","."),3012119). assertion_content_comment(nartR('tObjectDeviceUsingEnergyTypeFn','tElectricity'),s("The","collection","of","all","electrical","devices",".","A","type","of","#$","PoweredDevice.","."),3011219). assertion_content_comment(nartR('tObjectMerchandiseRelatedToFn','actAthleticActivity'),s("The","collection","of","all","sports","merchandise",".","A","type","of","#$","ManufacturedGoods","."),3011744). assertion_content_comment(nartR('tObjectMerchandiseRelatedToFn','actSexualCopulation'),s("The","collection","of","all","sex","merchandise",".","A","type","of","#$","ManufacturedGoods","."),3011715). assertion_content_comment(nartR('tObjectModelFn','tObjectAirplane'),s("The","collection","of","all","model","airplanes",".","A","type","of","#$","Model-Artifact","."),3011524). assertion_content_comment(nartR('tObjectModelFn','tObjectAutomobile'),s("The","collection","of","all","model","cars",".","A","type","of","#$","Model-Artifact","."),3011526). assertion_content_comment(nartR('tObjectModelFn','tObjectHelicopter'),s("The","collection","of","all","model","helicopters",".","A","type","of","#$","Model-Artifact","."),3011527). assertion_content_comment(nartR('tObjectModelFn','tObjectMotorcycle'),s("The","collection","of","all","model","motorcycles",".","A","type","of","#$","Model-Artifact","."),3011528). assertion_content_comment(nartR('tObjectModelFn','tObjectRocketPropelledTransportationDevice'),s("The","collection","of","all","model","rockets",".","A","type","of","#$","Model-Artifact","."),3011529). assertion_content_comment(nartR('tObjectModelFn','tObjectTrainTransportationDevice'),s("The","collection","of","all","model","trains",".","A","type","of","#$","Model-Artifact","."),3011530). assertion_content_comment(nartR('tObjectModelFn','tObjectTruck'),s("The","collection","of","all","model","trucks",".","A","type","of","#$","Model-Artifact","."),3011531). assertion_content_comment(nartR('tObjectModelFn','tObjectWatercraftSurface'),s("The","collection","of","all","model","boats",".","A","type","of","#$","Model-Artifact","."),3011525). assertion_content_comment(nartR('tObjectSportsVersionFn','tObjectGunPortable'),s("Guns","used","for","sports",",","and","not","for","hunting/killing",".","Examples","|","|","include","guns","used","in","skeet","shooting","."),1084052). assertion_content_comment(nartR('tObjectToyVersionFn','mobPerson'),s("The","collection","of","all","toy","people",".","A","type","of","#$","Toy","."),3012083). assertion_content_comment(nartR('tObjectToyVersionFn','tClazzAnimal'),s("The","collection","of","all","toy","animals",".","A","type","of","#$","Toy","."),3012078). assertion_content_comment(nartR('tObjectToyVersionFn','tClazzBearAnimal'),s("The","collection","of","all","toy","bears",".","A","type","of","#$","Toy","."),3011050). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectAirplane'),s("The","collection","of","all","toy","airplanes",".","A","type","of","#$","Toy","."),3012077). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectAutomobile'),s("The","collection","of","all","toy","cars",".","A","type","of","#$","Toy","."),3012080). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectBalloon'),s("The","collection","of","all","toy","balloons",".","A","type","of","#$","Toy","."),3012079). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectHandgun'),s("The","collection","of","all","toy","handguns",".","A","type","of","#$","Toy","."),3012081). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectMilitaryVehicle'),s("The","collection","of","all","toy","military","vehicles",".","A","type","of","#$","Toy",".","The","concept","toy","military","vehicle","is","an","#$","ArtifactTypeByGenericCategory","and","a","#$","SpatiallyDisjointObjectType","."),3032803). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectMotorcycle'),s("The","collection","of","all","toy","motorcycles",".","A","type","of","#$","Toy","."),3012082). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectRaceCar'),s("The","collection","of","all","toy","race","cars",".","A","type","of","#$","Toy","."),3012084). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectSafeTheLocker'),s("The","collection","of","all","piggy","banks",".","A","type","of","#$","Toy","."),3011616). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectTrainCar'),s("The","collection","of","all","toy","train","cars",".","A","type","of","#$","Toy","."),3012088). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectTrainTransportationDevice'),s("The","collection","of","all","toy","trains",".","A","type","of","#$","Toy","."),3012087). assertion_content_comment(nartR('tObjectToyVersionFn','tObjectTruck'),s("The","collection","of","all","toy","trucks",".","A","type","of","#$","Toy","."),3012089). assertion_content_comment(nartR('tObjectToyVersionFn','tPlaceLikeHouseModern'),s("The","collection","of","all","playhouses",".","A","type","of","#$","Toy","."),3011622). assertion_content_comment(nartR('tObjectToyVersionFn','tPlaceLikeRailway'),s("The","collection","of","all","toy","rails",".","A","type","of","#$","Toy","."),3012085). assertion_content_comment(nartR('tObjectWineOfRegionFn','iBourgogneRegionFrance'),s("The","collection","of","all","Burgundy","wines",".","A","type","of","French","wine","."),3011075). assertion_content_comment(nartR('tPartTypeFlowerFn','tClazzDandelionPlant'),s("The","collection","of","all","dandelion","flowers",".","A","type","of","#$","Flower-BotanicalPart","."),3011173). assertion_content_comment(nartR('tPartTypeFlowerFn','tClazzMagnoliaTree'),s("The","collection","of","all","magnolias",".","A","type","of","#$","Flower-BotanicalPart","."),3011455). assertion_content_comment(nartR('tPartTypeFlowerFn','tClazzPoppyPlant'),s("The","collection","of","all","poppies",".","A","type","of","#$","Flower-BotanicalPart","."),3011632). assertion_content_comment(nartR('tPartTypeFlowerFn','tClazzSunflowerPlant'),s("The","collection","of","all","sunflowers",".","A","type","of","#$","Flower-BotanicalPart","."),3011763). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzAfricanOilPalm'),s("The","collection","of","all","African","oil","palm","fruits",",","from","which","palm","oil","is","derived",".","A","type","of","#$","Fruit","."),3010946). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzAlmondTree'),s("The","collection","of","all","almonds",".","A","type","of","#$","Nut-TheFruit",",","#$","EdibleFruit",",","and","#$","EdibleNut","."),3010960). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzAppleTree'),s("The","collection","of","individual","apples","."),1046760). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzAvocadoTree'),s("The","collection","of","all","avocados","(","fruits","of","avocado","trees",")","A","type","of","#$","Fruit","."),3010997). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzBananaTree'),s("The","collection","of","all","bananas","(","fruits","of","banana","trees",")","A","type","of","#$","Curved",",","#$","NotVeryRoundObject",",","and","#$","EdibleFruit","."),3011009). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzBeanPlant'),s("The","collection","of","all","beans",".","A","type","of","#$","Fruit","."),3011021). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzBlueberryBush'),s("The","collection","of","all","blueberries",".","A","type","of","#$","EdibleFruit","."),3011033). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzBreadfruitTree'),s("The","collection","of","all","breadfruits",".","A","type","of","#$","EdibleFruit","."),3011071). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzBreadfruitTree'),s("The","collection","of","individual","Breadfruits","."),1044656). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCantaloupePlant'),s("The","collection","of","all","cantaloupes",".","A","type","of","#$","Muskmelon","."),3011081). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCerealPlant'),s("The","collection","of","all","cereal",".","A","type","of","#$","Fruit","."),3011101). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCherryTree'),s("The","collection","of","all","cherries","(","fruits","of","cherry","trees",")","A","type","of","#$","StoneFruit","."),3011107). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzChestnutTree'),s("The","collection","of","all","chestnuts","(","nuts","of","chestnut","trees",")","A","type","of","#$","Nut-TheFruit","and","#$","EdibleNut","."),3011110). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCoconutPalm'),s("The","collection","of","all","coconuts",".","A","type","of","#$","Fruit","."),3011133). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCoconutPalm'),s("The","collection","of","individual","fruits","of","the","coconut","palm",";","contain","single","large","seeds","which","are","coconuts","."),1127333). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCranberryBush'),s("The","collection","of","all","cranberries",".","A","type","of","#$","Fruit","."),3011162). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzCucumberPlant'),s("The","collection","of","all","cucumbers","(","fruits","of","cucumber","plants",")","A","type","of","#$","Fruit","."),3011167). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzDatePalm'),s("The","collection","of","individual","dates","."),1100606). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzEggplantPlant'),s("The","collection","of","all","eggplants",".","A","type","of","#$","Fruit","."),3011218). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzFigTree'),s("The","collection","of","all","figs","(","fruits","of","fig","trees",")","A","type","of","#$","EdibleFruit","."),3011249). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzFigTree'),s("The","collection","of","individual","Figs","."),1044885). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzFilbertTree'),s("The","collection","of","all","cobnuts","(","fruit","of","the","filbert","tree",")","A","type","of","#$","Fruit","."),3011131). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzFlaxPlant'),s("The","collection","of","all","flax","fruits",".","A","type","of","#$","Fruit","."),3011255). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzFlaxPlant'),s("The","fruit","of","the","flax","plant",";","a","capsule","containing","about","10","flax","seeds",",","or","linseeds","."),1046051). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzGourdPlant'),s("The","collection","of","all","gourds",".","A","type","of","#$","Fruit","."),3011329). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzGrapefruitTree'),s("The","collection","of","all","grapefruit",".","A","type","of","#$","CitrusFruit","."),3011333). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzGrapeVine'),s("The","collection","of","all","grapes",".","A","type","of","#$","EdibleFruit","."),3011331). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzGrapeVine'),s("The","collection","of","individual","Grapes","."),1068331). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzHoneydewMelonPlant'),s("The","collection","of","all","honeydews",".","A","type","of","#$","Muskmelon","."),3011387). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzKiwifruitVine'),s("The","collection","of","all","kiwifruits",".","A","type","of","#$","Fruit","."),3011436). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLegumeThePlant'),s("The","collection","of","all","legumes",".","A","type","of","#$","Fruit","."),3011440). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLegumeThePlant'),s("The","kind","of","fruit","borne","by","members","of","the","legume","order","-","the","classic","pea","pod",",","which","splits","into","two","halves","when","dry","."),1045122). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLemonTree'),s("The","collection","of","all","lemons",".","A","type","of","#$","CitrusFruit","."),3011441). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLemonTree'),s("The","collection","of","individual","Lemons","."),1045349). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLimeTree'),s("The","collection","of","all","limes",".","A","type","of","#$","CitrusFruit","."),3011445). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLimeTree'),s("The","collection","of","individual","limes","."),1047207). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzLycheeTree'),s("The","collection","of","all","lychees",".","A","type","of","#$","Fruit","."),3011451). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzMangoTree'),s("The","collection","of","all","mangos",".","A","type","of","#$","EdibleFruit","."),3011457). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzMangoTree'),s("The","collection","of","individual","mangos","."),1075788). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzMelonPlant'),s("The","collection","of","all","melons",".","A","type","of","#$","Fruit","."),3011480). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzNutmegTree'),s("The","collection","of","all","nutmeg","fruits",".","A","type","of","#$","EdibleFruit","."),3011569). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzNutmegTree'),s("The","fruit","of","the","nutmeg","tree",",","containing","one","nutmeg","(","the","seed",")","and","its","associated","mace-the","spice","(","the","aril","of","the","seed",")"),1046292). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzOkraPlant'),s("The","collection","of","all","okra",".","A","type","of","#$","Fruit","."),3011576). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzOliveTree'),s("The","collection","of","all","olives",".","A","type","of","#$","EdibleFruit.","."),3011577). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzOrangeTree'),s("The","collection","of","all","oranges",".","A","type","of","#$","CitrusFruit","."),3011584). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzOrangeTree'),s("The","collection","of","individual","oranges","."),1047439). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPeachTree'),s("The","collection","of","all","peaches",".","A","type","of","#$","StoneFruit","."),3011603). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPearTree'),s("The","collection","of","all","pears",".","A","type","of","#$","EdibleFruit","and","#$","Smooth","."),3011604). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPecanTree'),s("The","collection","of","all","pecans",".","A","type","of","#$","Nut-TheFruit",",","#$","EdibleFruit",",","and","#$","EdibleNut","."),3011605). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPepperPlant'),s("The","collection","of","all","peppers","(","fruits","of","pepper","plants",")","A","type","of","#$","Fruit","."),3011607). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPineapplePlant'),s("The","collection","of","individual","pineapples","."),3859700). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPlumTree'),s("The","collection","of","all","plums",".","A","type","of","#$","StoneFruit","."),3011624). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPlumTree'),s("The","collection","of","individual","plums","."),1086622). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPomegranateTree'),s("The","collection","of","all","pomegranates",".","A","type","of","#$","Fruit","."),3011630). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzPumpkinPlant'),s("The","collection","of","all","pumpkins",".","A","type","of","#$","Fruit","."),3011660). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzSesamePlant'),s("The","collection","of","all","sesame","fruits",".","A","type","of","#$","Fruit","."),3011714). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzSesamePlant'),s("The","fruits","of","the","sesame","plant",";","seeds","inside","are","sesame","seeds",";","fruits","are","dry","when","mature","and","dehisce","[","open","up","]",",","releasing","the","seeds","."),1046520). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzSquashPlant'),s("The","collection","of","all","squashes",".","A","type","of","#$","Fruit","."),3011745). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzStrawberryPlant'),s("The","collection","of","all","strawberries",".","A","type","of","#$","EdibleFruit","."),3011755). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzTomatoPlant'),s("The","collection","of","all","tomatoes",".","A","type","of","#$","Fruit","."),3012072). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzVanillaOrchid'),s("Known","as","vanilla","beans","\"",";","the","fruit","of","the","vanilla","orchid",",","rich","in","vanillin","which","is","extracted","to","be","used","as","a","flavoring","."),1106041). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzVanillaOrchid'),s("The","collection","of","all","vanilla","beans",".","A","type","of","#$","Fruit","."),3012104). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzWalnutTree'),s("The","collection","of","all","walnuts",".","A","type","of","#$","Nut-TheFruit",",","#$","EdibleFruit",",","and","#$","EdibleNut","."),3012122). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzWatermelonPlant'),s("The","collection","of","all","watermelons",".","A","type","of","#$","Fruit","."),3012126). assertion_content_comment(nartR('tPartTypeFruitFn','tClazzZucchiniPlant'),s("The","collection","of","all","zucchinis",".","A","type","of","squash","."),3012143). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzCatnipPlant'),s("The","collection","of","all","Nepeta","Cataria","leaf",".","A","type","of","#$","Leaf","."),3011546). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzCocaPlant'),s("The","collection","of","all","coca","plant","leaves",".","A","type","of","#$","Leaf","."),3011132). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzGrassPlant'),s("The","collection","of","all","grass","leaf",".","A","type","of","#$","Leaf","."),3011336). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzHolly'),s("The","collection","of","all","holly","leaves",".","A","type","of","#$","SimpleLeaf","."),3011384). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzMapleTree'),s("The","collection","of","all","maple","leaves",".","A","type","of","#$","SimpleLeaf","."),3011462). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzMintFloweringPlant'),s("The","collection","of","all","mint","leaf",".","A","type","of","#$","Leaf","."),3011510). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzParsleyPlant'),s("The","collection","of","all","parsley","leaf",".","A","type","of","#$","Leaf",".","\"","(","#$","LeafFn","#$","ParsleyPlant",")","\"","is","a","#$","SpatiallyDisjointObjectType","."),3011601). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzSisalPlant'),s("The","collection","of","all","sisal","leaves",".","A","type","of","#$","Leaf","."),3011723). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzTobaccoPlant'),s("The","collection","of","all","tobacco","leaves",".","A","type","of","#$","Leaf","."),3012071). assertion_content_comment(nartR('tPartTypeLeafFn','tClazzWalnutTree'),s("The","collection","of","all","walnut","tree","leaf",".","A","type","of","#$","PinnatelyCompoundLeaf","."),3012123). assertion_content_comment(nartR('tPartTypeOrganismPartTypeFn','tClazzBird','tPartTypeDigestiveSystem'),s("The","collection","of","all","bird","digestive","tracts",".","A","type","of","#$","DigestiveSystem","."),3011031). assertion_content_comment(nartR('tPartTypeOrganismPartTypeFn','tClazzFish','tPartTypeBoneBodyPart'),s("The","collection","of","all","fishbones",".","A","type","of","#$","Bone-BodyPart","."),3011251). assertion_content_comment(nartR('tPartTypeOrganismPartTypeFn','tClazzGooseBird','tPartTypeLiver'),s("The","collection","of","all","goose","livers",".","A","type","of","#$","Liver","."),3011328). assertion_content_comment(nartR('tPartTypeOrganismPartTypeFn','tClazzHomoSapiens','tWholeBody'),s("The","collection","of","all","human","bodies",".","A","type","of","#$","WholeBody","."),3011392). assertion_content_comment(nartR('tPartTypeOrganismPartTypeFn','tClazzVertebrate','tPartTypeEye'),s("The","kind","of","eye","that","is","typical","of","#$","Vertebrates","."),1083411). assertion_content_comment(nartR('tPartTypePartTypeEntirePortionFn','tCell','tPartTypeCytoplasm'),s("The","living","part","of","the","cell","outside","of","the","nucleus","and","within","the","plasma","membrane","in","which","the","cisternal","and","membrane-bound","organelles","lie","."),1113532). assertion_content_comment(nartR('tPartTypePollenFn','tClazzRagweed'),s("The","collection","of","all","ragweed","pollen",".","A","type","of","#$","Pollen",".","Ragweed","pollen","is","#$","TangibleStuffCompositionType","."),3011665). assertion_content_comment(nartR('tPartTypeRootFn','tClazzArrowrootPlant'),s("The","collection","of","all","roots","of","arrowroot","plants",".","A","type","of","#$","Rhizome","and","#$","Root","."),3010991). assertion_content_comment(nartR('tPartTypeRootFn','tClazzBeetPlant'),s("The","collection","of","all","beet","root",".","A","type","of","#$","Root","."),3011025). assertion_content_comment(nartR('tPartTypeRootFn','tClazzCarrotPlant'),s("The","collection","of","all","carrots",".","A","type","of","#$","Root","."),3011089). assertion_content_comment(nartR('tPartTypeRootFn','tClazzCassavaPlant'),s("The","collection","of","all","cassavas",".","A","type","of","#$","Root","."),3011091). assertion_content_comment(nartR('tPartTypeRootFn','tClazzGingerPlant'),s("The","collection","of","all","ginger",".","A","type","of","#$","Rhizome",",","#$","Spice",",","and","#$","Root","."),3011297). assertion_content_comment(nartR('tPartTypeRootFn','tClazzHorseradishPlant'),s("The","collection","of","all","horseradish","root",".","A","type","of","#$","Root","."),3011390). assertion_content_comment(nartR('tPartTypeRootFn','tClazzPotatoPlant'),s("The","collection","of","all","potatoes",".","A","type","of","#$","Root","and","#$","FoodIngredientOnly","."),3011638). assertion_content_comment(nartR('tPartTypeRootFn','tClazzRadishPlant'),s("The","collection","of","all","radish","plant","roots",".","A","type","of","#$","Root","."),3011664). assertion_content_comment(nartR('tPartTypeRootFn','tClazzYamPlant'),s("The","collection","of","all","yams",".","A","type","of","#$","Root","."),3012141). assertion_content_comment(nartR('tPartTypeSeedFn','tClazzCastorBeanPlant'),s("The","collection","of","all","castor","bean","seeds",".","A","type","of","#$","Seed","and","#$","ToxicSubstance","."),3011092). assertion_content_comment(nartR('tPartTypeSeedFn','tClazzCoffeeBush'),s("The","collection","of","all","coffee","beans","(","seeds","of","coffee","bushes",")","A","type","of","#$","Seed","and","#$","ExternalAnatomicalPart","."),3011136). assertion_content_comment(nartR('tPartTypeSeedFn','tClazzCottonPlant'),s("The","collection","of","all","cotton","seeds",".","A","type","of","#$","Seed","and","#$","InternalAnatomicalPart","."),3011155). 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assertion_content_comment('oboGo_AcetylCoacarboxylaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","acetyl-CoA","+","HCO3-","=","ADP","+","phosphate","+","malonyl-CoA","."),4186569). assertion_content_comment('oboGo_AcetylCoacarboxylasecomplex',s("A","protein","complex","that","catalyzes","the","first","step","in","long-chain","fatty","acid","biosynthesis",".","For","example",",","in","E",".","coli","the","complex","is","heterohexameric","and","composed","of","biotin","carbonyl","carrier","protein",",","biotin","carboxylase","and","the","acetate","CoA-transferase","complex","."),4023728). assertion_content_comment('oboGo_AcetylCoacarboxylasekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","[","acetyl-CoA","carboxylase","]","=","ADP","+","[","acetyl-CoA","carboxylase","]","phosphate","."),4267259). assertion_content_comment('oboGo_AcetylCoacarboxylasePhosphataseactivity',s("Catalysis","of","the","reaction",":","[","acetyl-CoA","carboxylase","]","-phosphate","+","H2O","=","[","acetyl-CoA","carboxylase","]","+","phosphate","."),4267337). assertion_content_comment('oboGo_AcetylCoacatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","acetyl-CoA",",","a","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","acetylated","."),4010364). assertion_content_comment('oboGo_AcetylCoacMyristoyltransferaseactivity',s("Catalysis","of","the","reaction",":","myristoyl-CoA","+","acetyl-CoA","=","3-oxopalmitoyl-CoA","+","CoA","."),4277771). assertion_content_comment('oboGo_AcetylCoa_Coaantiporteractivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","(","out",")","+","CoA","(","in",")","=","acetyl-CoA","(","in",")","+","CoA","(","out",")"),4296405). assertion_content_comment('oboGo_AcetylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","H","(","2",")","O","=","acetate","+","CoA","+","H","(","+",")"),4187180). assertion_content_comment('oboGo_AcetylCoa_LGlutamatenAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","acetyl-CoA","=","N-acetyl-L-glutamate","+","CoA","+","H","(","+",")"),4213523). assertion_content_comment('oboGo_AcetylCoametabolicprocess',s("The","chemical","reactions","and","pathways","involving","acetyl-CoA",",","a","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","acetylated",";","it","is","a","metabolite","derived","from","several","pathways","(","e.g",".","glycolysis",",","fatty","acid","oxidation",",","amino-acid","catabolism",")","and","is","further","metabolized","by","the","tricarboxylic","acid","cycle",".","It","is","a","key","intermediate","in","lipid","and","terpenoid","biosynthesis","."),4010328). assertion_content_comment('oboGo_AcetylCoasynthetaseacetyltransferaseactivity',s("Catalysis","of","the","acetylation","of","residue","Lys609","of","the","enzyme","acetyl-CoA","synthetase",",","using","acetyl-CoA","as","substrate","."),4328800). assertion_content_comment('oboGo_AcetylCoatransmembranetransport',s("The","process","in","which","acetyl-CoA","is","transported","from","one","side","of","a","membrane","to","the","other","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Acetyl-CoA","is","a","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","acetylated",";","it","is","a","metabolite","derived","from","several","pathways","(","e.g",".","glycolysis",",","fatty","acid","oxidation",",","amino-acid","catabolism",")","and","is","further","metabolized","by","the","tricarboxylic","acid","cycle",".","It","is","a","key","intermediate","in","lipid","and","terpenoid","biosynthesis","."),4382872). assertion_content_comment('oboGo_AcetylCoatransporteractivity',s("Enables","the","directed","movement","of","acetyl-CoA","into",",","out","of","or","within","a","cell",",","or","between","cells",".","Acetyl-CoA","is","a","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","acetylated",";","it","is","a","metabolite","derived","from","several","pathways","(","e.g",".","glycolysis",",","fatty","acid","oxidation",",","amino-acid","catabolism",")","and","is","further","metabolized","by","the","tricarboxylic","acid","cycle",".","It","is","a","key","intermediate","in","lipid","and","terpenoid","biosynthesis","."),4255004). assertion_content_comment('oboGo_AcetylCoatransport',s("The","directed","movement","of","acetyl-CoA","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Acetyl-CoA","is","a","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","acetylated",";","it","is","a","metabolite","derived","from","several","pathways","(","e.g",".","glycolysis",",","fatty","acid","oxidation",",","amino-acid","catabolism",")","and","is","further","metabolized","by","the","tricarboxylic","acid","cycle",".","It","is","a","key","intermediate","in","lipid","and","terpenoid","biosynthesis","."),4294329). assertion_content_comment('oboGo_AcetylCoA_Z_3_Hexen_1_OlAcetyltransferaseActivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","(","Z",")","-3-hexen-1-ol","=","CoA","+","(","Z",")","-3-hexen-1-yl","acetate","."),4332541). assertion_content_comment('oboGo_AcetylenecarboxylateHydrataseActivityProducing3Hydroxypropenoate',s("Catalysis","of","the","reaction",":","3-hydroxypropenoate","=","propynoate","+","H2O","."),4183348). assertion_content_comment('oboGo_AcetylenecarboxylateHydrataseActivityProducing3Oxopropanoate',s("Catalysis","of","the","reaction",":","3-oxopropanoate","=","propynoate","+","H2O","."),4270499). assertion_content_comment('oboGo_Acetylgalactosaminyl_O_Glycosyl_GlycoproteinBeta_13_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-galactosalaminyl-R","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-beta-D-glucosaminyl-1",",","3-N-acetyl-D-galactosaminyl-R","+","UDP","."),4366514). assertion_content_comment('oboGo_Acetylgalactosaminyl_O_Glycosyl_GlycoproteinBeta_16_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","N-acetyl-beta-D-glucosaminyl-1",",","3-N-acetyl-D-galactosaminyl-R","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-beta-D-glucosaminyl-1",",","6-","(","N-acetyl-beta-D-glucosaminyl-1",",","3",")","-N-acetyl-D-galactosaminyl-R","+","UDP","."),4366499). assertion_content_comment('oboGo_AcetylserotoninOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","N-acetylserotonin","=","S-adenosyl-L-homocysteine","+","melatonin",".","Melatonin","is","also","known","as","N-acetyl-5-methoxytryptamine","."),4267680). assertion_content_comment('oboGo_ACGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","ACG","codon","."),4339938). assertion_content_comment('oboGo_AcidAminoacidligaseactivity',s("Catalysis","of","the","ligation","of","an","acid","to","an","amino","acid","via","a","carbon-nitrogen","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4155385). assertion_content_comment('oboGo_AcidAmmoniaoramideligaseactivity',s("Catalysis","of","the","ligation","of","an","acid","to","ammonia","(","NH3",")","or","an","amide","via","a","carbon-nitrogen","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4207738). assertion_content_comment('oboGo_AcidCoaligasegdpFormingactivity',s("Catalysis","of","the","reaction",":","a","carboxylate","+","CoA","+","GTP","=","acyl-CoA","+","GDP","+","H","(","+",")","+","phosphate","."),4372067). assertion_content_comment('oboGo_AcidThiolligaseactivity',s("Catalysis","of","the","joining","of","an","acid","and","a","thiol","via","a","carbon-sulfur","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4173842). assertion_content_comment('oboGo_AcireductoneDioxygenaseIronIIRequiringactivity',s("Catalysis","of","the","reaction",":","1",",","2-dihydroxy-5-","(","methylthio",")","pent-1-en-3-one","+","O","(","2",")","=","4-methylthio-2-oxobutanoate","+","formate","+","H","(","+",")"),4332434). assertion_content_comment('oboGo_AcireductoneDioxygenaseNi2Requiringactivity',s("Catalysis","of","the","reaction",":","1",",","2-dihydroxy-5-","(","methylthio",")","pent-1-en-3-one","+","O","(","2",")","=","3-","(","methylthio",")","propanoate","+","CO","+","formate","."),4332452). assertion_content_comment('oboGo_AconitateDeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","trans-aconitate","=","cis-aconitate","."),4372092). assertion_content_comment('oboGo_AcryloylCoareductaseactivity',s("Catalysis","of","the","reaction",":","reduced","electron","transferring","flavoprotein","+","NADH","+","acrylyl-CoA","=","NAD","+","+","oxidized","electron","transferring","flavoprotein","+","propionyl-CoA","."),4328167). assertion_content_comment('oboGo_AcrylylCoareductasenadphactivity',s("Catalysis","of","the","reaction",":","acrylyl-CoA","+","NADPH","+","H","+","=","propionyl-CoA","+","NADP","+"),4328123). assertion_content_comment('oboGo_ActinCrossLinkingactivity',s("OBSOLETE",".","Interacting","selectively","with","two","actin","filaments","to","anchor","them","together","."),4193158). assertion_content_comment('oboGo_ActinDependentatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","This","reaction","requires","the","presence","of","an","actin","filament","to","accelerate","release","of","ADP","and","phosphate","."),4307013). assertion_content_comment('oboGo_ActinFilamentBasedmovement',s("Movement","of","organelles","or","other","particles","along","actin","filaments",",","or","sliding","of","actin","filaments","past","each","other",",","mediated","by","motor","proteins","."),4038929). assertion_content_comment('oboGo_ActinFilamentBasedprocess',s("Any","cellular","process","that","depends","upon","or","alters","the","actin","cytoskeleton",",","that","part","of","the","cytoskeleton","comprising","actin","filaments","and","their","associated","proteins","."),3978666). assertion_content_comment('oboGo_ActinMediatedcellcontraction',s("The","actin","filament-based","process","in","which","cytoplasmic","actin","filaments","slide","past","one","another","resulting","in","contraction","of","all","or","part","of","the","cell","body","."),4005434). assertion_content_comment('oboGo_ActinMyosinfilamentsliding',s("The","sliding","movement","of","actin","thin","filaments","and","myosin","thick","filaments","past","each","other","."),4038932). assertion_content_comment('oboGo_ActinobacteriumTypecellwallbiogenesis',s("A","cellular","process","that","results","in","the","biosynthesis","of","constituent","macromolecules",",","assembly",",","and","arrangement","of","constituent","parts","of","a","cell","wall","of","the","type","found","in","Actinobacteria",".","The","cell","wall","is","the","rigid","or","semi-rigid","envelope","lying","outside","the","cell","membrane",".","Actinobacterial","cell","walls","contain","characteristic","mycolic","acids",",","of","which","some","are","covalently","linked","to","the","cell","wall","peptidoglycan","and","others","accumulate","at","the","cell","surface","."),4129352). assertion_content_comment('oboGo_ActinomyceteTypesporeformation',s("The","process","in","which","differentiated",",","resting","cells","are","formed","from","a","substrate","mycelium",";","characteristic","of","many","members","of","the","order","Actinomycetales","."),4354882). assertion_content_comment('oboGo_ActinPolymerizationDependentcellmotilityinvolvedinmigrationofsymbiontinhost',s("A","process","involved","in","the","controlled","movement","of","a","bacterial","cell","within","a","host","cell",",","powered","by","the","continuous","polymerization","of","host","actin","at","one","pole","of","the","cell","."),4136599). assertion_content_comment('oboGo_ActinPolymerizationDependentcellmotility',s("A","process","involved","in","the","controlled","movement","of","a","bacterial","cell","powered","by","the","continuous","polymerization","of","actin","at","one","pole","of","the","cell","."),4136595). assertion_content_comment('oboGo_ActivatedCD4PositivealphaBetatcellproliferation',s("The","expansion","of","an","activated","CD4-positive",",","alpha-beta","T","cell","population","by","cell","division","."),4380778). assertion_content_comment('oboGo_ActivatedCD8PositivealphaBetatcellproliferation',s("The","expansion","of","an","activated","CD8-positive",",","alpha-beta","T","cell","population","by","cell","division","."),4380787). assertion_content_comment('oboGo_ActivationInducedbcellapoptosis',s("B","cell","apoptosis","that","occurs","upon","engagement","of","either","the","B","cell","receptor","or","CD40",".","Engagement","of","either","receptor",",","but","not","both",",","leads","to","expression","of","fas","or","related","receptors","that","make","the","B","cell","susceptible","to","fas-ligand","mediated","death","."),4168636). assertion_content_comment('oboGo_ActivationInducedcelldeathoftcells',s("A","type","of","T","cell","apoptosis","that","occurs","towards","the","end","of","the","expansion","phase","following","the","initial","activation","of","mature","T","cells","by","antigen","and","is","triggered","by","T","cell","receptor","stimulation","and","signals","transmitted","via","various","surface-expressed","members","of","the","TNF","receptor","family","such","as","Fas","ligand",",","Fas",",","and","TNF","and","the","p55","and","p75","TNF","receptors","."),4011459). assertion_content_comment('oboGo_ActivationOfAdenylateCyclaseActivityByGlucoseTriggeredgProteinsignalingpathway',s("Any","glucose-triggered","process","that","initiates","the","activity","of","an","inactive","adenylate","cyclase","that","is","an","integral","part","of","the","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","resulting","in","a","subsequent","change","in","the","concentration","of","cyclic","AMP","."),4336562). assertion_content_comment('oboGo_ActivationOfAdenylateCyclaseActivityByGProteinsignalingpathway',s("Any","process","that","initiates","the","activity","of","an","inactive","adenylate","cyclase","that","is","an","integral","part","of","the","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","resulting","in","a","subsequent","change","in","the","concentration","of","cyclic","AMP","."),4170463). assertion_content_comment('oboGo_ActivationOfAnaphasePromotingcomplexactivityinvolvedinmeioticcellcycle',s("Any","process","that","initiates","the","ubiquitin","ligase","activity","of","the","anaphase-promoting","complex","during","the","meiotic","cell","cycle","."),4286372). assertion_content_comment('oboGo_ActivationOfAnaphasePromotingcomplexactivity',s("Any","process","that","initiates","the","ubiquitin","ligase","activity","of","the","anaphase-promoting","complex","."),4012434). assertion_content_comment('oboGo_ActivationOfMitoticAnaphasePromotingcomplexactivity',s("Any","process","that","initiates","the","ubiquitin","ligase","activity","of","the","anaphase-promoting","complex","that","regulates","the","mitotic","metaphase/anaphase","transition","."),4012446). assertion_content_comment('oboGo_ActivationOfNFKappabInducingkinaseactivity',s("The","stimulation","of","the","activity","of","NF-kappaB-inducing","kinase","through","phosphorylation","at","specific","residues","."),4016735). assertion_content_comment('oboGo_ActivationOfPhospholipaseA2ActivityByCalciumMediatedsignaling',s("A","series","of","molecular","signals","that","leads","to","the","upregulation","of","calcium-dependent","phospholipase","A2","activity","in","response","to","the","signal","."),4318027). assertion_content_comment('oboGo_ActivationOfPhospholipaseCActivityByGProteincoupledreceptorproteinsignalingpathwaycoupledtoip3secondmessenger',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","followed","by","the","activation","of","phospholipase","C","and","the","subsequent","release","of","inositol","trisphosphate","."),4049058). assertion_content_comment('oboGo_ActivationOfPhospholipaseDActivityByGProteincoupledreceptorproteinsignalingpathway',s("A","G-protein","coupled","signaling","pathway","that","results","in","the","activation","of","phospholipase","D",",","causing","an","increase","in","cellular","levels","of","phosphatidic","acid","."),4322064). assertion_content_comment('oboGo_ActivationOfProApoptoticgeneproducts',s("The","conversion","of","proteins","that","induce","or","sustain","apoptosis","to","an","active","form","."),4020260). assertion_content_comment('oboGo_ActivationOfProteinKinaseCActivityByGProteincoupledreceptorproteinsignalingpathway',s("The","initiation","of","the","activity","of","the","inactive","enzyme","protein","kinase","C","as","the","result","of","a","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand","."),4236251). assertion_content_comment('oboGo_ActivationOfStoreOperatedcalciumchannelactivity',s("A","process","that","initiates","the","activity","of","an","inactive","store-operated","calcium","channel","."),4329781). assertion_content_comment('oboGo_ActivationOfTryptophan5Monooxygenaseactivity',s("The","process","in","which","the","tryptophan","5-monooxygenase","enzyme","is","changed","so","that","it","can","carry","out","its","enzymatic","activity","."),4014285). assertion_content_comment('oboGo_ActiveInductionOfCellMediatedimmuneresponseinhostbyvirus',s("The","intentional",",","virally-encoded","stimulation","of","a","cell-mediated","host","defense","response","to","viral","infection","."),4356614). assertion_content_comment('oboGo_ACUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","ACU","codon","."),4340030). assertion_content_comment('oboGo_AculeacinAdeacylaseactivity',s("Catalysis","of","the","hydrolysis","of","the","amide","bond","in","aculeacin","A","and","related","neutral","lipopeptide","antibiotics",",","releasing","the","long-chain","fatty","acid","side-chain","."),4345153). assertion_content_comment('oboGo_AcuteInflammatoryResponseToNonAntigenicstimulus',s("An","acute","inflammatory","response","to","non-antigenic","stimuli","such","as","heat","or","physical","trauma","."),4000549). assertion_content_comment('oboGo_AcutePhaseresponseproteinactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4193048). assertion_content_comment('oboGo_AcutePhaseresponse',s("An","acute","inflammatory","response","that","involves","non-antibody","proteins","whose","concentrations","in","the","plasma","increase","in","response","to","infection","or","injury","of","homeothermic","animals","."),3995919). assertion_content_comment('oboGo_AcylAcylCarrierProteindesaturaseactivity',s("Catalysis","of","the","reaction",":","stearoyl-","[","acyl-carrier","protein","]","+","reduced","acceptor","+","O2","=","oleoyl-","[","acyl-carrier","protein","]","+","acceptor","+","H2O",".","The","enzyme","requires","ferredoxin","."),4298380). assertion_content_comment('oboGo_AcylAcylCarrierProteinhydrolaseactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","H2O","=","[","acyl-carrier","protein","]","+","a","fatty","acid","."),4208669). assertion_content_comment('oboGo_AcylAcylCarrierProteinPhospholipidoAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","O-","(","2-acyl-sn-glycero-3-phospho",")","ethanolamine","=","[","acyl-carrier","protein","]","+","O-","(","1-beta-acyl-2-acyl-sn-glycero-3-phospho",")","ethanolamine","."),4251773). assertion_content_comment('oboGo_AcylAcylCarrierProteinUdpNAcetylglucosamineoAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-3-hydroxytetradecanoyl-","[","acyl-carrier","protein","]","+","UDP-N-acetylglucosamine","=","[","acyl-carrier","protein","]","+","UDP-3-O-","(","3-hydroxytetradecanoyl",")","-N-acetylglucosamine","."),4249091). assertion_content_comment('oboGo_AcylaminoacylPeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","acylaminoacyl-peptide","+","H2O","=","acylamino","acid","+","peptide","."),4210294). assertion_content_comment('oboGo_AcylCarrierProteinbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","acyl-carrier","protein","."),4316175). assertion_content_comment('oboGo_AcylCarrierProteinphosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","[","acyl-carrier","protein","]","+","H2O","=","4","'","-phosphopantetheine","+","apoprotein","."),4251787). assertion_content_comment('oboGo_AcylCarrierProteinsAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","[","acyl-carrier","protein","]","=","CoA","+","acetyl-","[","acyl-carrier","protein","]"),4208746). assertion_content_comment('oboGo_AcylCarrierProteinsMalonyltransferaseactivity',s("Catalysis","of","the","reaction",":","malonyl-CoA","+","[","acyl-carrier","protein","]","=","CoA","+","malonyl-","[","acyl-carrier","protein","]"),4208788). assertion_content_comment('oboGo_AcylCoabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","acyl-CoA",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","an","acyl","group","."),4101287). assertion_content_comment('oboGo_AcylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","acceptor","=","2",",","3-dehydroacyl-CoA","+","reduced","acceptor","."),4177837). assertion_content_comment('oboGo_AcylCoadehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","NADP","+","=","2",",","3-dehydroacyl-CoA","+","NADPH","+","H","+"),4372022). assertion_content_comment('oboGo_AcylCoadelta11Desaturaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","reduced","acceptor","+","O2","=","delta11-acyl-CoA","+","acceptor","+","2","H2O","."),4267591). assertion_content_comment('oboGo_AcylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","H2O","=","CoA","+","a","carboxylate","."),4372009). assertion_content_comment('oboGo_AcylCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","long-chain","carboxylic","acid","+","CoA","=","AMP","+","diphosphate","+","an","acyl-CoA",";","long-chain","fatty","acids","have","chain","lengths","of","C12-18","."),4186271). assertion_content_comment('oboGo_AcylCoametabolicprocess',s("The","chemical","reactions","and","pathways","involving","acyl-CoA",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","an","acyl","group","."),4101268). assertion_content_comment('oboGo_AcylCoanAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","from","acyl-CoA","to","a","nitrogen","atom","on","an","acceptor","molecule","."),4237873). assertion_content_comment('oboGo_AcylCoaoracylbinding',s("OBSOLETE",".","Interacting","selectively","with","acyl-CoA","or","acyl",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","a","fatty","acyl","group",",","or","any","group","formally","derived","by","removal","of","a","hydroxyl","group","from","the","acid","function","of","an","organic","acid","."),4218966). assertion_content_comment('oboGo_AcylCoaoxidaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","O2","=","trans-2",",","3-dehydroacyl-CoA","+","hydrogen","peroxide","."),4186291). assertion_content_comment('oboGo_AcylCoathioesteraseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","H2O","=","corresponding","fatty","acid","+","CoA","."),4304599). assertion_content_comment('oboGo_AcylglycerolOAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","to","an","oxygen","atom","on","the","acylglycerol","molecule","."),4188509). assertion_content_comment('oboGo_AcylglyceronePhosphatereductaseactivity',s("Catalysis","of","the","reaction",":","1-palmitoylglycerol-3-phosphate","+","NADP","+","=","palmitoylglycerone","phosphate","+","NADPH","+","H","+"),4346079). assertion_content_comment('oboGo_AcylLysinedeacylaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","N6-acyl-L-lysine","=","L-lysine","+","a","carboxylate","."),4266364). assertion_content_comment('oboGo_Acyl_PhosphateGlycerol_3_PhosphateAcyltransferaseActivity',s("Catalysis","of","the","reaction",":","acyl","phosphate","+","sn-glycerol","3-phosphate","=","1-acyl-sn-glycerol","3-phosphate","+","orthophosphate","."),4327976). assertion_content_comment('oboGo_AcylPhosphateHexosephosphotransferaseactivity',s("Catalysis","of","the","reaction",":","D-hexose","+","acyl","phosphate","=","D-hexose","phosphate","+","an","acid","."),4369046). assertion_content_comment('oboGo_AdaptiveImmuneResponseBasedOnSomaticRecombinationOfImmuneReceptorsBuiltFromLeucineRichrepeatdomains',s("An","immune","response","based","on","directed","amplification","of","specific","receptors","for","antigen","produced","through","a","somatic","diversification","process","that","includes","somatic","recombination","of","variable","lymphocyte","receptors","(","VLR",")","incorporating","leucine-rich","repeat","(","LRR",")","domains",",","and","allowing","for","enhanced","responses","upon","subsequent","exposures","to","the","same","antigen","(","immunological","memory",")","Examples","of","this","process","are","found","in","jawless","fish",",","including","the","lampreys","(","Petromyzontidae",")","and","hagfishes","(","Myxinidae",")"),4380766). assertion_content_comment('oboGo_ADD9alphaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","androsta-1",",","4-diene-3",",","17-dione","+","reduced","ferredoxin","+","O2","=","3-hydroxy-9",",","10-secoandrosta-1",",","3",",","5","(","10",")","-triene-9",",","17-dione","+","H2O","+","oxidized","ferredoxin","."),4350448). assertion_content_comment('oboGo_Adenosine35Bisphosphatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","adenosine","3","'",",","5","'","-bisphosphate","from","one","side","of","a","membrane","to","the","other","."),4166892). assertion_content_comment('oboGo_Adenosine35Bisphosphatetransmembranetransport',s("The","directed","movement","of","adenosine","3","'",",","5","'","-bisphosphate","across","a","membrane","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4164458). assertion_content_comment('oboGo_Adenosine5Monophosphoramidaseactivity',s("Catalysis","of","the","reaction",":","adenosine","5","'","-monophosphoramidate","=","AMP","+","NH2",".","Other","substrates","include","AMP-morpholidate",",","AMP-N-alanine","methyl","ester","and","AMP-alpha-acetyl","lysine","methyl","ester","."),4325569). assertion_content_comment('oboGo_AdenosineDiphosphataseactivity',s("Catalysis","of","the","reaction",":","ADP","+","H2O","=","AMP","+","phosphate","."),4318455). assertion_content_comment('oboGo_AdenosinePhosphatedeaminaseactivity',s("Catalysis","of","the","reaction",":","5","'","-AMP","+","H2O","=","5","'","-IMP","+","NH3","."),4371939). assertion_content_comment('oboGo_AdenosineReceptorActivityGProteincoupled',s("Combining","with","adenosine","and","transmitting","the","signal","to","a","heterotrimeric","G-protein","complex","to","initiate","a","change","in","cell","activity","."),4300929). assertion_content_comment('oboGo_AdenosineTetraphosphataseactivity',s("Catalysis","of","the","reaction",":","adenosine","5","'","-tetraphosphate","+","H2O","=","ATP","+","phosphate","."),4371902). assertion_content_comment('oboGo_AdenosylcobinamideGdpribazoletransferaseactivity',s("Catalysis","of","the","reaction",":","adenosylcobinamide-GDP","+","alpha-ribazole","=","GMP","+","adenosylcobalamin","."),4287062). assertion_content_comment('oboGo_AdenosylcobinamidePhosphatesynthaseactivity',s("Catalysis","of","the","reactions",":","ATP","+","adenosylcobyric","acid","+","(","R",")","-1-aminopropan-2-yl","phosphate","=","ADP","+","phosphate","+","adenosylcobinamide","phosphate",",","and","ATP","+","adenosylcobyric","acid","+","(","R",")","-1-aminopropan-2-ol","=","ADP","+","phosphate","+","adenosylcobinamide","."),4326156). assertion_content_comment('oboGo_AdenosylcobyricAcidSynthaseGlutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","4","L-glutamine","+","adenosylcob","(","III",")","yrinate","a",",","c-diamide","+","4","ATP","+","4","H","(","2",")","O","=","4","L-glutamate","+","adenosylcobyrate","+","4","ADP","+","8","H","(","+",")","+","4","phosphate","."),4183055). assertion_content_comment('oboGo_AdenosylFluoridesynthaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","fluoride","=","5","'","-deoxy-5","'","-fluoroadenosine","+","L-methionine","."),4343896). assertion_content_comment('oboGo_Adenosylmethionine_8_Amino_7_OxononanoateTransaminaseActivity',s("Catalysis","of","the","reaction",":","8-amino-7-oxononanoate","+","S-adenosyl-L-methionine","(","1","+",")","=","7",",","8-diaminononanoate","+","S-adenosyl-4-methylthio-2-oxobutanoate","."),4213077). assertion_content_comment('oboGo_AdenylNucleotideexchangefactoractivity',s("Stimulates","the","hydrolysis","and","exchange","of","adenyl","nucleotides","by","other","proteins","."),4363682). assertion_content_comment('oboGo_AdenylylGlutamateAmmonialigasehydrolaseactivity',s("Catalysis","of","the","reaction",":","adenylyl-","[","L-glutamate",":","ammonia","ligase","(","ADP-forming",")","]","+","H2O","=","AMP","+","[","L-glutamate",":","ammonia","ligase","(","ADP-forming",")","]"),4368558). assertion_content_comment('oboGo_AdenylylsulfateAmmoniaadenylyltransferaseactivity',s("Catalysis","of","the","reaction",":","5","'","-adenylyl","sulfate","+","NH","(","4",")","(","+",")","=","adenosine","5","'","-phosphoramidate","+","2","H","(","+",")","+","sulfate","."),4367963). assertion_content_comment('oboGo_AdenylylSulfatereductaseactivity',s("Catalysis","of","the","reaction",":","AMP","+","sulfite","+","acceptor","=","adenylyl","sulfate","+","reduced","acceptor","."),4262087). assertion_content_comment('oboGo_AdenylylSulfatereductaseglutathioneactivity',s("Catalysis","of","the","reaction",":","AMP","+","glutathione","disulfide","+","H","(","+",")","+","sulfite","=","5","'","-adenylyl","sulfate","+","2","glutathione","."),4342474). assertion_content_comment('oboGo_AdenylylSulfatereductasethioredoxinactivity',s("Catalysis","of","the","reaction",":","AMP","+","sulfite","+","thioredoxin","disulfide","=","5","'","-adenylyl","sulfate","+","thioredoxin","."),4326646). assertion_content_comment('oboGo_AdipateCoaligaseactivity',s("Catalysis","of","the","reaction",":","adipate","+","CoASH","=","adipyl-CoA","+","OH-","."),4349855). assertion_content_comment('oboGo_AdiponectinMediatedsignalingpathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","adiponectin","binding","to","a","cell","surface","receptor","."),4338074). assertion_content_comment('oboGo_Adonirubin3Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","adonirubin","+","a","reduced","electron","acceptor","+","oxygen","=","3S",",","3","'","S-astaxanthin","+","an","oxidized","electron","acceptor","+","H2O","."),4191091). assertion_content_comment('oboGo_ADPActivatednucleotidereceptoractivity',s("Combining","with","adenosine","and","transmitting","the","signal","to","a","heterotrimeric","G-protein","complex","to","initiate","a","change","in","cell","activity",",","activated","by","ADP","."),4300952). assertion_content_comment('oboGo_ADPDependentmediumChainAcylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","a","medium-chain","acyl-CoA","=","a","medium-chain","carboxylate","+","CoA","."),4368588). assertion_content_comment('oboGo_ADPDependentshortChainAcylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","a","short-chain","acyl-CoA","=","a","short-chain","carboxylate","+","CoA","."),4368696). assertion_content_comment('oboGo_ADPDRibosebinding',s("Interacting","selectively","and","non-covalently","with","ADP-D-ribose",",","an","ADP-aldose","having","ribose","as","the","aldose","fragment","."),4157736). assertion_content_comment('oboGo_ADPGlucosepyrophosphohydrolaseactivity',s("Catalysis","of","the","reaction",":","ADP-glucose","+","H2O","=","AMP","+","glucose-1-phosphate","."),4181840). assertion_content_comment('oboGo_ADPGlyceromannoHeptose6Epimeraseactivity',s("Catalysis","of","the","reaction",":","ADP-D-glycero-D-manno-heptose","=","ADP-L-glycero-D-manno-heptose","."),4252124). assertion_content_comment('oboGo_ADPHeptoseLipopolysaccharideheptosyltransferaseactivity',s("Catalysis","of","the","reaction",":","heptosyl-KDO2-lipid","A","+","ADP-L-glycero-beta-D-manno-heptose","=","heptosyl2-KDO2-lipid","A","+","ADP","+","H","+"),4252183). assertion_content_comment('oboGo_ADPLGlyceroDMannoHeptosesynthaseactivity',"OBSOLETE.",4252160). assertion_content_comment('oboGo_ADPPhosphoglyceratephosphataseactivity',s("Catalysis","of","the","reaction",":","3-ADP-2-phosphoglycerate","+","H","(","2",")","O","=","3-ADP-glycerate","+","phosphate","."),4372301). assertion_content_comment('oboGo_ADPRibosediphosphataseactivity',s("Catalysis","of","the","reaction",":","ADP-ribose","+","H2O","=","AMP","+","D-ribose","5-phosphate","."),4372314). assertion_content_comment('oboGo_ADPRibosepyrophosphohydrolaseactivity',s("Catalysis","of","the","reaction",":","ADP-ribose","+","H2O","=","AMP","+","ribose-1-phosphate","."),4181849). assertion_content_comment('oboGo_ADPRibosylargininehydrolaseactivity',s("Catalysis","of","the","reaction",":","N2-","(","ADP-D-ribosyl",")","-L-arginine","+","H2O","=","L-arginine","+","ADP-ribose","."),4189693). assertion_content_comment('oboGo_ADPRibosylationfactorbinding',s("Interacting","selectively","and","non-covalently","with","ARF",",","ADP-ribosylation","factor",",","a","small","monomeric","cytosolic","GTPase","that",",","when","bound","to","GTP",",","binds","to","the","membranes","of","cells","."),4312160). assertion_content_comment('oboGo_ADPRibosylDinitrogenreductasehydrolaseactivity',s("Catalysis","of","the","reaction",":","ADP-ribosyl-","[","dinitrogen","reductase","]","=","adenosine","diphosphate","ribose","+","[","dinitrogen","reductase","]"),4369979). assertion_content_comment('oboGo_ADPSpecificglucokinaseactivity',s("Catalysis","of","the","reaction",":","ADP","+","D-glucose","=","AMP","+","D-glucose","6-phosphate","."),4326951). assertion_content_comment('oboGo_ADPSpecificphosphofructokinaseactivity',s("Catalysis","of","the","reaction",":","ADP","+","D-fructose","6-phosphate","=","AMP","+","D-fructose","1",",","6-bisphosphate","."),4326936). assertion_content_comment('oboGo_ADPSugardiphosphataseactivity',s("Catalysis","of","the","reaction",":","ADP-sugar","+","H2O","=","AMP","+","sugar","1-phosphate","."),4181833). assertion_content_comment('oboGo_ADPThymidinekinaseactivity',s("Catalysis","of","the","reaction",":","ADP","+","thymidine","=","AMP","+","thymidine","5","'","-phosphate","."),4372424). assertion_content_comment('oboGo_AdrenodoxinTypeferredoxin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259485). assertion_content_comment('oboGo_AdultChitinBasedcuticledevelopment',s("Synthesis","and","deposition","of","the","chitin-based","cuticle","of","adults","following","the","apolysis","of","the","pupal","cuticle",".","The","adult","insect","cuticle","contains","cuticullin",",","a","protein","epicuticle","and","a","lamellate","procuticle",".","An","example","of","this","process","is","adult","chitin-based","cuticle","development","in","Drosophila","melanogaster","."),4015188). assertion_content_comment('oboGo_AdultChitinBasedcuticlepatternformation',s("The","process","that","gives","rise","to","the","patterns","of","cell","differentiation","that","will","arise","in","the","chitin-based","adult","cuticle",".","An","example","of","this","process","is","adult","chitin-based","cuticle","pattern","formation","in","Drosophila","melanogaster","."),4072531). assertion_content_comment('oboGo_AdultChitinContainingcuticlepigmentation',s("Establishment","of","the","adult","pattern","of","pigmentation","in","the","chitin-containing","cuticle","of","an","organism",".","An","example","of","this","is","the","adult","cuticle","pigmentation","process","in","Drosophila","melanogaster","."),4104067). assertion_content_comment('oboGo_AdvancedGlycationEndProductreceptoractivity',s("Combining","with","advanced","glycation","end-products","to","initiate","a","change","in","cell","activity","."),4275487). assertion_content_comment('oboGo_AerobicBeta_123456_HexachlorocyclohexaneMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","beta-1",",","2",",","3",",","4",",","5",",","6-hexachlorocyclohexane","that","occur","in","presence","of","oxygen","."),4273157). assertion_content_comment('oboGo_AerobicPhenolContainingcompoundbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","presence","of","oxygen","."),4351834). assertion_content_comment('oboGo_AerobicPhenolContainingcompoundcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","presence","of","oxygen","."),4351791). assertion_content_comment('oboGo_AerobicPhenolContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","presence","of","oxygen","."),4272742). assertion_content_comment('oboGo_AF_1DomainBinding',s("Interacting","selectively","and","non-covalently","with","the","AF-1","domain","of","a","protein",",","a","ligand-independent","transactivation","domain","which","is","required","for","the","full","transcriptional","activity","of","the","receptor","."),4277335). assertion_content_comment('oboGo_AF_2DomainBinding',s("Interacting","selectively","and","non-covalently","with","the","AF-2","domain","of","a","protein",",","a","highly","conserved","ligand-dependent","transactivation","domain","which","is","essential","for","receptor-mediated","transcriptional","activation","."),4277326). assertion_content_comment('oboGo_AGACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AGA","codon","."),4339400). assertion_content_comment('oboGo_AgaritineGammaGlutamyltransferaseactivity',s("Catalysis","of","the","reaction",":","agaritine","+","acceptor-NH2","=","4-hydroxymethylphenylhydrazine","+","gamma-L-glutamyl-acceptor","."),4266633). assertion_content_comment('oboGo_AGCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AGC","codon","."),4339994). assertion_content_comment('oboGo_AgeDependentgeneralmetabolicdeclineinvolvedinchronologicalcellaging',s("A","process","of","general","metabolic","decline","that","arises","in","non-dividing","cells","as","they","age",",","and","alters","cellular","metabolism","to","cause","a","decline","in","cell","function","."),3980174). assertion_content_comment('oboGo_AgeDependentgeneralmetabolicdeclineinvolvedinreplicativecellaging',s("A","process","of","general","metabolic","decline","that","arises","in","dividing","cells","as","they","age",",","and","alters","cellular","metabolism","to","cause","a","decline","in","cell","function","."),3980036). assertion_content_comment('oboGo_AgeDependentgeneralmetabolicdecline',s("A","developmental","process","that","arises","as","the","cell","progresses","toward","the","end","of","its","lifespan","and","cause","changes","cellular","metabolism",",","resulting","in","a","decline","in","cell","function",";","for","example",",","one","aspect","of","general","metabolic","decline","is","a","decrease","in","the","efficiency","of","protein","synthesis","."),3979787). assertion_content_comment('oboGo_AgeDependentresponsetooxidativestressinvolvedinchronologicalcellaging',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","occurring","in","non-dividing","cells","as","they","age","as","a","result","of","oxidative","stress",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),3980321). assertion_content_comment('oboGo_AgeDependentresponsetooxidativestressinvolvedinreplicativecellaging',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","occurring","in","dividing","cells","as","they","age","as","a","result","of","oxidative","stress",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),3980040). assertion_content_comment('oboGo_AgeDependentresponsetooxidativestress',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","(","in","terms","of","movement",",","secretion",",","enzyme","production",",","gene","expression",",","etc.",")","as","a","result","of","oxidative","stress",",","a","state","often","resulting","from","exposure","to","high","levels","of","reactive","oxygen","species",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),3979812). assertion_content_comment('oboGo_AgeDependentresponsetoreactiveoxygenspeciesinvolvedinchronologicalcellaging',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","occurring","in","non-dividing","cells","as","they","age","as","a","result","of","reactive","oxygen","species",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),4362250). assertion_content_comment('oboGo_AgeDependentresponsetoreactiveoxygenspeciesinvolvedinreplicativecellaging',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","occurring","during","the","process","of","replicative","cell","aging","as","a","result","of","reactive","oxygen","species",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),3980116). assertion_content_comment('oboGo_AgeDependentresponsetoreactiveoxygenspecies',s("A","change","in","state","or","activity","of","a","cell","or","an","organism","(","in","terms","of","movement",",","secretion",",","enzyme","production",",","gene","expression",",","etc.",")","as","a","result","of","reactive","oxygen","species",",","where","the","change","varies","according","to","the","age","of","the","cell","or","organism","."),3980088). assertion_content_comment('oboGo_AgeDependenttelomereshortening',s("Progressive","reduction","in","length","of","the","telomeres",",","the","termini","of","eukaryotic","chromosomes",",","that","occurs","as","part","of","the","cellular","aging","process","."),4362279). assertion_content_comment('oboGo_AgeDependentyeastcellsizeincrease',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4234748). assertion_content_comment('oboGo_AGGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AGG","codon","."),4339389). assertion_content_comment('oboGo_AgmatineN4Coumaroyltransferaseactivity',s("Catalysis","of","the","reaction",":","4-coumaroyl-CoA","+","agmatine","=","N-","(","4-guanidiniumylbutyl",")","-4-hydroxycinnamamide","+","CoA","+","H","(","+",")"),4372355). assertion_content_comment('oboGo_AGUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AGU","codon","."),4340005). assertion_content_comment('oboGo_AlaeOfCollagenAndCuticulinBasedcuticleextracellularmatrix',s("Raised",",","thickened","cuticular","ridges","that","run","longitudinally",",","and","in","parallel",",","along","the","left","and","right","sides","of","the","animal",".","The","alae","lie","above","the","hypodermal","cells","known","as","the","lateral","seam","cells",".","In","C",".","elegans",",","alae","are","produced","in","L1","larvae",",","dauer","larvae","and","adult","stage","animals",",","where","they","consist","of","three",",","five",",","and","three","ridges","of","distinct","morphology",",","respectively","."),4108879). assertion_content_comment('oboGo_AlanineGlyoxylatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-alanine","+","glyoxylate","=","pyruvate","+","glycine","."),4253953). assertion_content_comment('oboGo_AlanineOxoAcidtransaminaseactivity',s("Catalysis","of","the","reaction",":","L-alanine","+","a","2-oxo","acid","=","pyruvate","+","an","L-amino","acid","."),4213235). assertion_content_comment('oboGo_AlanineOxomalonatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-alanine","+","oxomalonate","=","aminomalonate","+","pyruvate","."),4368919). assertion_content_comment('oboGo_AlanineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-alanine","+","tRNA","(","Ala",")","=","AMP","+","diphosphate","+","L-alanyl-tRNA","(","Ala",")"),4199096). assertion_content_comment('oboGo_AlanylTrnaaminoacylation',s("The","process","of","coupling","alanine","to","alanyl-tRNA",",","catalyzed","by","alanyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179819). assertion_content_comment('oboGo_AlaTrnaprohydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","misacylated","Ala-tRNA","(","Pro",")"),4328708). assertion_content_comment('oboGo_AlcoholDehydrogenaseActivityIronDependent',s("Catalysis","of","the","reaction",":","an","alcohol","+","NAD","+","=","an","aldehyde","or","ketone","+","NADH","+","H","+",",","requiring","the","presence","of","iron","."),4213309). assertion_content_comment('oboGo_AlcoholDehydrogenaseActivityMetalIonIndependent',s("Catalysis","of","the","reaction",":","an","alcohol","+","NAD","+","=","an","aldehyde","or","ketone","+","NADH","+","H","+",";","can","proceed","in","the","absence","of","a","metal","ion","."),4213217). assertion_content_comment('oboGo_AlcoholDehydrogenaseActivityZincDependent',s("Catalysis","of","the","reaction",":","an","alcohol","+","NAD","+","=","an","aldehyde","or","ketone","+","NADH","+","H","+",",","requiring","the","presence","of","zinc","."),4213208). assertion_content_comment('oboGo_AlcoholDehydrogenaseNADPActivity_9',s("Catalysis","of","the","reaction",":","an","alcohol","+","NAD","(","P",")","+","=","an","aldehyde","+","NAD","(","P",")","H","+","H","+"),4281698). assertion_content_comment('oboGo_AlcoholOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","an","alcohol","=","CoA","+","an","acetyl","ester","."),4213296). assertion_content_comment('oboGo_AlcoholOAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","to","an","oxygen","atom","on","an","alcohol","acceptor","molecule","."),4213288). assertion_content_comment('oboGo_AlcoholOButanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","butanoyl-CoA","+","an","alcohol","=","CoA","+","a","butyl","ester","."),4355361). assertion_content_comment('oboGo_AlcoholOCinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","an","alcohol","+","1-O-trans-cinnamoyl-beta-D-glucopyranose","=","beta-D-glucose","+","alkyl","cinnamate","."),4366250). assertion_content_comment('oboGo_AlcoholODecanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","decanoyl-CoA","+","an","alcohol","=","CoA","+","a","decyl","ester","."),4355232). assertion_content_comment('oboGo_AlcoholOHexanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","hexanoyl-CoA","+","an","alcohol","=","CoA","+","a","hexyl","ester","."),4355265). assertion_content_comment('oboGo_AlcoholOOctanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","octanoyl-CoA","+","an","alcohol","=","CoA","+","an","octyl","ester","."),4355199). assertion_content_comment('oboGo_AldehydeDehydrogenaseFADIndependentactivity',s("Catalysis","of","the","reaction",":","an","aldehyde","+","H2O","+","acceptor","=","a","carboxylate","+","reduced","acceptor","."),4342555). assertion_content_comment('oboGo_AldehydeDehydrogenaseNADPActivity_6',s("Catalysis","of","the","reaction",":","an","aldehyde","+","NADP","+","+","H2O","=","an","acid","+","NADPH","+","H","+"),4341903). assertion_content_comment('oboGo_AldehydeDehydrogenasePyrroloquinolineQuinoneactivity',s("Catalysis","of","the","reaction",":","H2O","+","acceptor","+","an","aldehyde","=","donor-H2","+","an","acid","."),4365928). assertion_content_comment('oboGo_AldehydeLyaseactivity',s("Catalysis","of","the","cleavage","of","a","C-C","bond","in","a","molecule","containing","a","hydroxyl","group","and","a","carbonyl","group","to","form","two","smaller","molecules",",","each","being","an","aldehyde","or","a","ketone","."),4073961). assertion_content_comment('oboGo_Alditol_NADP1Oxidoreductaseactivity',s("Catalysis","of","the","reaction",":","an","alditol","+","NADP","+","=","an","aldose","+","NADPH","+","H","+"),4213362). assertion_content_comment('oboGo_AldoKetoreductasenadpactivity',s("Catalysis","of","the","reaction",":","an","alcohol","+","NADP","+","=","an","aldehyde","or","a","ketone","+","NADPH","+","H","+"),4191356). assertion_content_comment('oboGo_Aldos_2_UloseDehydrataseActivity',s("Catalysis","of","the","reactions",":","1",",","5-anhydro-D-fructose","=","2-hydroxy-2-","(","hydroxymethyl",")","-2H-pyran-3","(","6H",")","-one","+","H2O",";","(","1a",")","1",",","5-anhydro-D-fructose","=","1",",","5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose","+","H2O","and","(","1b",")","1",",","5-anhydro-4-deoxy-D-glycero-hex-3-en-2-ulose","=","2-hydroxy-2-","(","hydroxymethyl",")","-2H-pyran-3","(","6H",")","-one","."),4345223). assertion_content_comment('oboGo_Aldose1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-aldose","+","NAD","+","=","D-aldonolactone","+","NADH","."),4372184). assertion_content_comment('oboGo_Aldose1Epimeraseactivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","=","beta-D-glucose",".","Also","acts","on","L-arabinose",",","D-xylose",",","D-galactose",",","maltose","and","lactose","."),4213391). assertion_content_comment('oboGo_Aldose_1_PhosphateAdenylyltransferaseActivity',s("Catalysis","of","the","reaction",":","aldose","1-phosphate","+","ADP","=","phosphate","+","ADP-aldose","."),4368159). assertion_content_comment('oboGo_Aldose_1_PhosphateNucleotidyltransferaseActivity',s("Catalysis","of","the","reaction",":","aldose","1-phosphate","+","NDP","=","phosphate","+","NDP-aldose","."),4368210). assertion_content_comment('oboGo_Aldose_6_PhosphateReductaseNADPHActivity',s("Catalysis","of","the","reaction",":","D-glucitol","6-phosphate","+","NADP","(","+",")","=","D-glucose","6-phosphate","+","H","(","+",")","+","NADPH","."),4372196). assertion_content_comment('oboGo_AldoseBetaDFructosyltransferaseactivity',s("Catalysis","of","the","reaction",":","alpha-D-aldosyl1","beta-D-fructoside","+","D-aldose2","=","D-aldose1","+","alpha-D-aldosyl2","beta-D-fructoside","."),4372162). assertion_content_comment('oboGo_AliphaticAmineoxidaseactivity',s("Catalysis","of","the","reaction",":","an","aliphatic","amine","+","H2O","+","O2","=","an","aldehyde","+","NH3","+","hydrogen","peroxide","+","H","+"),4186660). assertion_content_comment('oboGo_Alizarin2BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","alizarin","+","UDP-D-glucose","=","1-hydroxy-2-","(","beta-D-glucosyloxy",")","-9",",","10-anthraquinone","+","H","(","+",")","+","UDP","."),4372239). assertion_content_comment('oboGo_Alkan_1_OlDehydrogenaseAcceptorActivity',s("Catalysis","of","the","reaction",":","primary","alcohol","+","acceptor","=","aldehyde","+","reduced","acceptor","."),4372252). assertion_content_comment('oboGo_AlkanalMonooxygenaseFMNLinkedactivity',s("Catalysis","of","the","reaction",":","R-CHO","+","reduced","FMN","+","O2","=","R-COOH","+","FMN","+","H2O","+","light","."),4372214). assertion_content_comment('oboGo_Alkane1Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","octane","+","reduced","rubredoxin","+","O2","=","1-octanol","+","oxidized","rubredoxin","+","H2O","."),4276794). assertion_content_comment('oboGo_AlkylbaseDNANGlycosylaseactivity',s("Catalysis","of","the","hydrolysis","of","alkylated","DNA",",","releasing","3-methyladenine",",","3-methylguanine",",","7-methylguanine","and","7-methyladenine",".","Enzymes","with","this","activity","recognize","and","remove","alkylated","purines","and","pyrimidines","by","cleaving","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic","or","apyrimidinic","(","AP",")","site","."),4184079). assertion_content_comment('oboGo_AlkylglyceronePhosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","1-acyl-glycerone","3-phosphate","+","a","long-chain","alcohol","=","1-alkyl-glycerone","3-phosphate","+","a","long-chain","acid","anion","."),4252976). assertion_content_comment('oboGo_Alkylglycerophosphate2OAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","1-alkyl-sn-glycerol","3-phosphate","+","acetyl-CoA","=","1-alkyl-2-acetyl-sn-glycerol","3-phosphate","+","CoA","."),4365252). assertion_content_comment('oboGo_AlleneOxidecyclaseactivity',s("Catalysis","of","the","reaction",":","(","9Z",",","13S",",","15Z",")","-12",",","13-epoxyoctadeca-9",",","11",",","15-trienoate","=","(","15Z",")","-12-oxophyto-10",",","15-dienoate","."),4351292). assertion_content_comment('oboGo_Allose6Phosphateisomeraseactivity',s("Catalysis","of","the","reaction",":","D-allose-6-phosphate","=","D-allulose-6-phosphate","."),4249193). assertion_content_comment('oboGo_AllTransretinalbinding',s("Interacting","selectively","and","non-covalently","with","all-trans","retinal",",","a","compound","that","plays","an","important","role","in","the","visual","process","in","most","vertebrates",".","All-trans","retinal","(","trans","r.",",","visual","yellow",")","results","from","the","bleaching","of","rhodopsin","by","light",",","in","which","the","11-cis","form","is","converted","to","the","all-trans","form",".","Retinal","is","one","of","the","forms","of","vitamin","A","."),4219050). assertion_content_comment('oboGo_AllTransRetinol1314Reductaseactivity',s("Catalysis","of","the","reaction",":","all-trans-13",",","14-dihydroretinol","+","A","=","all-trans-retinol","+","AH","(","2",")","Note","that","this","reaction","has","only","been","observed","to","occur","in","the","opposite","direction","."),4281219). assertion_content_comment('oboGo_AllTransRetinylPalmitatehydrolaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","retinol-palmitate","=","palmitate","+","retinol","."),4368712). assertion_content_comment('oboGo_Allulose6Phosphate3Epimeraseactivity',s("Catalysis","of","the","reaction",":","D-allulose","6-phosphate","=","D-fructose","6-phosphate","."),4349294). assertion_content_comment('oboGo_AllylAlcoholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","allyl","alcohol","+","NADP","(","+",")","=","acrolein","+","H","(","+",")","+","NADPH","."),4372609). assertion_content_comment('oboGo_Alpha10Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha10","subunit","and","one","beta1","subunit","."),4354712). assertion_content_comment('oboGo_Alpha11Beta1integrinCollagentypeicomplex',s("A","protein","complex","that","consists","of","an","alpha11-beta1","integrin","complex","bound","to","a","type","I","collagen","."),4167018). assertion_content_comment('oboGo_Alpha11Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha11","subunit","and","one","beta1","subunit","."),4354702). assertion_content_comment('oboGo_Alpha12Fucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","L-fucosyl","group","from","GDP-beta-L-fucose","to","an","acceptor","molecule","to","form","an","alpha","(","1",",","2",")","-linkage","."),4246443). assertion_content_comment('oboGo_Alpha_12_GalactosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","galactose","residue","from","a","donor","molecule",",","such","as","GDP-galactose","or","UDP-galactose",",","to","an","oligosaccharide",",","forming","an","alpha-1",",","2-linkage","."),4320150). assertion_content_comment('oboGo_Alpha_12_MannosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","mannose","residue","from","GDP-mannose","to","an","oligosaccharide",",","forming","an","alpha-1",",","2-linkage","."),4207352). assertion_content_comment('oboGo_Alpha13Fucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","L-fucosyl","group","from","GDP-beta-L-fucose","to","an","acceptor","molecule","to","form","an","alpha","(","1",",","3",")","-linkage","."),4269093). assertion_content_comment('oboGo_Alpha_13_GalactosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","galactose","residue","from","a","donor","molecule",",","such","as","GDP-galactose","or","UDP-galactose",",","to","an","oligosaccharide",",","forming","an","alpha-1",",","3-linkage","."),4384220). assertion_content_comment('oboGo_Alpha_13_GlucanSynthaseActivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","[","alpha-D-glucosyl-","(","1",",","3",")","]","n","=","UDP","+","[","alpha-D-glucosyl-","(","1",",","3",")","]","n","+","1","."),4372634). assertion_content_comment('oboGo_Alpha_13_Mannosylglycoprotein2_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","3-","(","alpha-D-mannosyl",")","-beta-D-mannosyl-R","+","UDP-N-acetyl-alpha-D-glucosamine","=","3-","(","2-","[","N-acetyl-beta-D-glucosaminyl","]","-alpha-D-mannosyl",")","-beta-D-mannosyl-R","+","H","(","+",")","+","UDP","."),4188436). assertion_content_comment('oboGo_Alpha_13_Mannosylglycoprotein4_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","(","N-acetyl-beta-D-glucosaminyl-1",",","2",")","-alpha-D-mannosyl-1",",","3-","(","beta-N-acetyl-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","6",")","-beta-D-mannosyl-R","=","UDP","+","N-acetyl-beta-D-glucosaminyl-1",",","4-","(","N-acetyl-D-glucosaminyl-1",",","2",")","-alpha-D-mannosyl-1",",","3-","(","beta-N-acetyl-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","6",")","-beta-D-mannosyl-R","."),4253910). assertion_content_comment('oboGo_Alpha_13_MannosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","mannose","residue","from","GDP-mannose","to","an","oligosaccharide",",","forming","an","alpha-1",",","3-linkage","."),4345537). assertion_content_comment('oboGo_Alpha_14_Glucan_ProteinSynthaseADP_FormingActivity',s("Catalysis","of","the","reaction",":","ADP-D-glucose","+","protein","=","alpha-D-glucosyl-protein","+","ADP","."),4366670). assertion_content_comment('oboGo_Alpha_14_GlucanSynthaseActivity',s("Catalysis","of","the","reaction",":","RDP-glucose","+","[","alpha-D-glucosyl-","(","1",",","4",")","]","n","=","RDP","+","[","alpha-D-glucosyl-","(","1",",","4",")","]","n","+","1",",","where","RDP","is","ADP","or","UDP","."),4338235). assertion_content_comment('oboGo_Alpha_14_MannosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","mannose","residue","from","GDP-mannose","to","an","oligosaccharide",",","forming","an","alpha-1",",","4-linkage","."),4280011). assertion_content_comment('oboGo_Alpha_14_N_AcetylgalactosaminyltransferaseActivity',s("Catalysis","of","the","transfer","of","an","N-acetylgalactosaminyl","residue","from","UDP-N-acetyl-galactosamine","to","an","acceptor","molecule",",","forming","an","alpha-1",",","4","linkage","."),4382573). assertion_content_comment('oboGo_Alpha16Fucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","L-fucosyl","group","from","GDP-beta-L-fucose","to","an","acceptor","molecule","to","form","an","alpha","(","1",",","6",")","-linkage","."),4253493). assertion_content_comment('oboGo_Alpha_16_Mannosylglycoprotein2_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","alpha-D-mannosyl-1",",","6-","(","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","3",")","-beta-D-mannosyl-R","=","UDP","+","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","6-","(","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","3",")","-beta-D-mannosyl-R","."),4253928). assertion_content_comment('oboGo_Alpha_16_Mannosyl_Glycoprotein4_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","N-acetyl-beta-D-glucosaminyl-1",",","6-beta-D-","(","N-acetyl-B-glucosaminyl-1",",","2",")","-beta-D-mannosyl-R","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-beta-D-glucosaminyl-1",",","6-beta-D-","(","N-acetyl-D-glucosaminyl-1",",","2-beta",")","-","(","N-acetyl-D-glucosaminyl-1",",","4-beta",")","-D-mannosyl-R","+","UDP","."),4367171). assertion_content_comment('oboGo_Alpha_16_Mannosyl_Glycoprotein6_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","3","(","6",")","-","(","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl",",","1",",","6","(","3",")",")","-beta-D-mannosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-R","=","UDP","+","N-acetyl-beta-D-glucosaminyl-1",",","2-","(","N-acetyl-beta-D-glucosaminyl-1",",","6",")","-1",",","2-alpha-D-mannosyl-1",",","3","(","6",")","-","(","N-acetyl-beta-D-glucosaminyl-1",",","2-alpha-D-mannosyl-1",",","6","(","3",")",")","-beta-D-mannosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-R",".","Only","branched","mannose","glycopeptides","with","non-reducing","N-acetylglucosamine","terminal","residues","act","as","acceptors","."),4311160). assertion_content_comment('oboGo_Alpha_16_MannosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","mannose","residue","from","GDP-mannose","to","an","oligosaccharide",",","forming","an","alpha-1",",","6-linkage","."),4345412). assertion_content_comment('oboGo_Alpha_16_MannosyltransferaseComplex',s("A","large",",","multiprotein","complex","with","alpha-1",",","6","mannosyltransferase","activity",",","located","in","the","cis","Golgi","membrane",";","adds","mannan","to","N-linked","glycans","on","proteins","."),3971968). assertion_content_comment('oboGo_Alpha_1AAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-1A","adrenergic","receptor","."),4322581). assertion_content_comment('oboGo_Alpha1Adrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","alpha1-adrenergic","receptors",";","the","activity","involves","transmitting","the","signal","to","the","Gq","alpha","subunit","of","a","heterotrimeric","G","protein","."),4197889). assertion_content_comment('oboGo_Alpha_1BAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-1B","adrenergic","receptor","."),4322571). assertion_content_comment('oboGo_Alpha1Beta1integrinAlpha3vicomplex',s("A","protein","complex","that","consists","of","an","alpha1-beta1","integrin","complex","bound","to","a","type","VI","collagen","triple","helix","containing","an","alpha3","(","VI",")","chain","."),4175991). assertion_content_comment('oboGo_Alpha1Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha1","subunit","and","one","beta1","subunit","."),4354452). assertion_content_comment('oboGo_Alpha1Beta1integrinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alpha1-beta1","integrin","complex","bound","to","tissue","transglutaminase","."),4166829). assertion_content_comment('oboGo_Alpha1Beta1integrinTyrosineProteinphosphatasenonReceptortype2complex',s("A","protein","complex","that","consists","of","an","alpha1-beta1","integrin","complex","bound","to","tyrosine-protein","phosphatase","non-receptor","type","2","."),4164675). assertion_content_comment('oboGo_Alpha_1DAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-1D","adrenergic","receptor","."),4322561). assertion_content_comment('oboGo_Alpha_1_Microglobulin_ChromophoreLinkage',s("The","covalent","linking","of","the","alpha-1-microglobulin","chromophore","to","the","protein",";","the","structure","of","the","chromophore","is","not","known",".","It","is","probably","heterogeneous","and","involving","two","cysteines","in","thioether","bonds","."),4232778). assertion_content_comment('oboGo_Alpha_2AAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-2A","adrenergic","receptor","."),4322551). assertion_content_comment('oboGo_Alpha2Adrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","alpha2-adrenergic","receptors",";","the","activity","involves","transmitting","the","signal","to","the","Gi","alpha","subunit","of","a","heterotrimeric","G","protein","."),4197899). assertion_content_comment('oboGo_Alpha_2BAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-2B","adrenergic","receptor","."),4322541). assertion_content_comment('oboGo_Alpha2Beta1integrinAlpha3vicomplex',s("A","protein","complex","that","consists","of","an","alpha2-beta1","integrin","complex","bound","to","a","type","VI","collagen","triple","helix","containing","an","alpha3","(","VI",")","chain","."),4175958). assertion_content_comment('oboGo_Alpha2Beta1integrinCd47complex',s("A","protein","complex","that","consists","of","an","alpha2-beta1","integrin","complex","bound","to","the","cell","surface","protein","CD47","."),4167051). assertion_content_comment('oboGo_Alpha2Beta1integrinChondroadherincomplex',s("A","protein","complex","that","consists","of","an","alpha2-beta1","integrin","complex","bound","to","the","cartilage","matrix","protein","chondroadherin","."),4167095). assertion_content_comment('oboGo_Alpha2Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha2","subunit","and","one","beta1","subunit","."),4354486). assertion_content_comment('oboGo_Alpha_2CAdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","alpha-2C","adrenergic","receptor","."),4322531). assertion_content_comment('oboGo_Alpha_2MacroglobulinReceptorActivity',s("Combining","with","an","alpha-2","macroglobulin","to","initiate","a","change","in","cell","activity","."),4302446). assertion_content_comment('oboGo_Alpha_2MacroglobulinReceptor_AssociatedProteinActivity',s("OBSOLETE",".","Interaction","with","the","alpha-2","macroglobulin","receptor","and","glycoprotein","gp330","forming","a","complex","with","the","alpha-2","macroglobulin","receptor","light","and","heavy","chains","."),4302437). assertion_content_comment('oboGo_Alpha_2Macroglobulin',s("OBSOLETE",".","Inhibition","of","proteinase","by","a","mechanism","involving","a","bait","region","which","contains","specific","sites",",","cleavage","of","which","induces","a","conformational","change","that","results","in","trapping","of","the","proteinase",";","following","cleavage","in","the","bait","region","a","thiolester","bond","is","hydrolyzed","and","mediates","the","covalent","binding","of","the","protein","to","the","proteinase",";","subsequently","epsilon-amino","groups","of","the","proteinase","react","with","thiolester","linkages","in","the","inhibitor","to","form","stable","amide","links",";","the","entrapped","proteinase","can","now","only","act","on","low","molecular","mass","substrates","."),4302508). assertion_content_comment('oboGo_Alpha3Beta1integrinBasigincomplex',s("A","protein","complex","that","consists","of","an","alpha3-beta1","integrin","complex","bound","to","the","cell","surface","protein","basigin","."),4167073). assertion_content_comment('oboGo_Alpha3Beta1integrinCd151complex',s("A","protein","complex","that","consists","of","an","alpha3-beta1","integrin","complex","bound","to","the","tetraspanin","CD151","."),4167347). assertion_content_comment('oboGo_Alpha3Beta1integrinCd63complex',s("A","protein","complex","that","consists","of","an","alpha3-beta1","integrin","complex","bound","to","the","tetraspanin","CD63","."),4167040). assertion_content_comment('oboGo_Alpha3Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha3","subunit","and","one","beta1","subunit","."),4354475). assertion_content_comment('oboGo_Alpha3Beta1integrinThrombospondincomplex',s("A","protein","complex","that","consists","of","an","alpha3-beta1","integrin","complex","bound","to","thrombospondin","."),4166741). assertion_content_comment('oboGo_Alpha3Beta1integrinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alpha3-beta1","integrin","complex","bound","to","tissue","transglutaminase","."),4166774). assertion_content_comment('oboGo_Alpha4Beta1integrinCd47complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","the","cell","surface","antigen","CD47","."),4164266). assertion_content_comment('oboGo_Alpha4Beta1integrinCd53complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","membrane","protein","CD53",",","a","member","of","the","tetraspan","family","."),4174922). assertion_content_comment('oboGo_Alpha4Beta1integrinCd63complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","membrane","protein","CD63",",","a","member","of","the","tetraspan","family","."),4174933). assertion_content_comment('oboGo_Alpha4Beta1integrinCd81complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","membrane","protein","CD81",",","a","member","of","the","tetraspan","family","."),4175052). assertion_content_comment('oboGo_Alpha4Beta1integrinCd82complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","membrane","protein","CD82",",","a","member","of","the","tetraspan","family","."),4175009). assertion_content_comment('oboGo_Alpha4Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha4","subunit","and","one","beta1","subunit","."),4354520). assertion_content_comment('oboGo_Alpha4Beta1integrinJam2complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","the","cell","adhesion","molecule","JAM2","."),4164470). assertion_content_comment('oboGo_Alpha4Beta1integrinPaxillincomplex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","paxillin","."),4164492). assertion_content_comment('oboGo_Alpha4_Beta1Integrin_Thrombospondin_1Complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","thrombospondin-1","."),4166952). assertion_content_comment('oboGo_Alpha4_Beta1Integrin_Thrombospondin_2Complex',s("A","protein","complex","that","consists","of","an","alpha4-beta1","integrin","complex","bound","to","thrombospondin-2","."),4166941). assertion_content_comment('oboGo_Alpha4_Beta4Integrin_EMILIN_1Complex',s("A","protein","complex","that","consists","of","an","alpha4-beta4","integrin","complex","bound","to","EMILIN-1","(","ElastinMicrofibril","Interface","Located","ProteIN",")"),4164354). assertion_content_comment('oboGo_Alpha4Beta7integrincomplex',s("An","integrin","complex","that","comprises","one","alpha4","subunit","and","one","beta7","subunit","."),4354531). assertion_content_comment('oboGo_Alpha5Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha5","subunit","and","one","beta1","subunit","."),4354582). assertion_content_comment('oboGo_Alpha5Beta1integrinEndostatincomplex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","endostatin",",","the","NC1","domain","of","the","alpha1","chain","of","type","XVIII","collagen","."),4164321). assertion_content_comment('oboGo_Alpha5Beta1integrinFibronectinNovcomplex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","fibronectin","and","the","extracellular","matrix","protein","NOV","."),4164299). assertion_content_comment('oboGo_Alpha5Beta1integrinFibronectinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","fibronectin","and","tissue","transglutaminase","."),4166763). assertion_content_comment('oboGo_Alpha5Beta1integrinLpp3complex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","lipid","phosphate","phosphohydrolase-3","."),4164609). assertion_content_comment('oboGo_Alpha5Beta1integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","osteopontin","."),4164719). assertion_content_comment('oboGo_Alpha5Beta1integrinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alpha5-beta1","integrin","complex","bound","to","tissue","transglutaminase","."),4167007). assertion_content_comment('oboGo_Alpha5Beta5FibronectinSfrp2complex',s("A","protein","complex","that","consists","of","an","alpha5-beta5","integrin","complex","bound","to","fibronectin","and","secreted","frizzled-related","protein","2","."),4164587). assertion_content_comment('oboGo_Alpha6Beta1integrinCd151complex',s("A","protein","complex","that","consists","of","an","alpha6-beta1","integrin","complex","bound","to","the","tetraspanin","CD151","."),4167336). assertion_content_comment('oboGo_Alpha6Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha6","subunit","and","one","beta1","subunit","."),4354571). assertion_content_comment('oboGo_Alpha6Beta1integrinCyr61complex',s("A","protein","complex","that","consists","of","an","alpha6-beta1","integrin","complex","bound","to","CYR61",",","a","cysteine-rich","protein","involved","in","angiogenesis","."),4164310). assertion_content_comment('oboGo_Alpha6Beta4integrinCd151complex',s("A","protein","complex","that","consists","of","an","alpha6-beta4","integrin","complex","bound","to","the","tetraspanin","CD151","."),4167270). assertion_content_comment('oboGo_Alpha6Beta4integrinCd9complex',s("A","protein","complex","that","consists","of","an","alpha6-beta4","integrin","complex","bound","to","the","cell","surface","protein","CD9","."),4166752). assertion_content_comment('oboGo_Alpha6Beta4integrincomplex',s("An","integrin","complex","that","comprises","one","alpha6","subunit","and","one","beta1","subunit","."),4354561). assertion_content_comment('oboGo_Alpha6Beta4integrinFyncomplex',s("A","protein","complex","that","consists","of","an","alpha6-beta4","integrin","complex","bound","to","the","Src","family","tyrosine","kinase","Fyn","."),4166796). assertion_content_comment('oboGo_Alpha6Beta4integrinLaminin5complex',s("A","protein","complex","that","consists","of","an","alpha6-beta4","integrin","complex","bound","to","laminin","5","."),4173180). assertion_content_comment('oboGo_Alpha6Beta4integrinShcGrb2complex',s("A","protein","complex","that","consists","of","an","alpha6-beta4","integrin","complex","bound","to","the","adaptor","proteins","Shc","and","Grb2","."),4173267). assertion_content_comment('oboGo_Alpha7Beta1integrinCd151complex',s("A","protein","complex","that","consists","of","an","alpha7-beta1","integrin","complex","bound","to","the","tetraspanin","CD151","."),4167259). assertion_content_comment('oboGo_Alpha7Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha7","subunit","and","one","beta1","subunit","."),4354551). assertion_content_comment('oboGo_Alpha7Beta1integrinFocaladhesionkinasecomplex',s("A","protein","complex","that","consists","of","an","alpha7-beta1","integrin","complex","bound","to","focal","adhesion","kinase","."),4164554). assertion_content_comment('oboGo_Alpha7_Beta1Integrin_LamininAlpha_2Complex',s("A","protein","complex","that","consists","of","an","alpha7-beta1","integrin","complex","bound","to","laminin","alpha-2","."),4164543). assertion_content_comment('oboGo_Alpha7Beta1integrinNicotinamideribosidekinasecomplex',s("A","protein","complex","that","consists","of","an","alpha7-beta1","integrin","complex","bound","to","nicotinamide","riboside","kinase","2","(","also","known","as","muscle","integrin","binding","protein",",","MIBP",")"),4164418). assertion_content_comment('oboGo_Alpha8Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha8","subunit","and","one","beta1","subunit","."),4354541). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam12complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM12","."),4166974). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam15complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM15","."),4167325). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam1complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM1","."),4167177). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam2complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM2","."),4167188). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam3complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM3","."),4167155). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam8complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM8","."),4164576). assertion_content_comment('oboGo_Alpha9Beta1integrinAdam9complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM9","."),4167166). assertion_content_comment('oboGo_Alpha9Beta1integrincomplex',s("An","integrin","complex","that","comprises","one","alpha9","subunit","and","one","beta1","subunit","."),4354612). assertion_content_comment('oboGo_Alpha9Beta1integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","osteopontin","."),4164686). assertion_content_comment('oboGo_Alpha9Beta1integrinTenascincomplex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","the","extracellular","matrix","protein","tenascin","."),4167029). assertion_content_comment('oboGo_Alpha9_Beta1Integrin_Thrombospondin_1Complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","thrombospondin-1","."),4164565). assertion_content_comment('oboGo_Alpha9_Beta1Integrin_VascularCellAdhesionMolecule_1Complex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","vascular","cell","adhesion","molecule-1","."),4167303). assertion_content_comment('oboGo_Alpha9Beta1integrinVegfAcomplex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","vascular","endothelial","growth","factor","A","."),4164653). assertion_content_comment('oboGo_Alpha9Beta1integrinVegfCcomplex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","vascular","endothelial","growth","factor","C","."),4164642). assertion_content_comment('oboGo_Alpha9Beta1integrinVegfDcomplex',s("A","protein","complex","that","consists","of","an","alpha9-beta1","integrin","complex","bound","to","vascular","endothelial","growth","factor","D","."),4164277). assertion_content_comment('oboGo_AlphaActininbinding',s("Interacting","selectively","and","non-covalently","with","alpha-actinin",",","one","of","a","family","of","proteins","that","cross-link","F-actin","as","antiparallel","homodimers",".","Alpha-actinin","has","a","molecular","mass","of","93-103","KDa",";","at","the","N-terminus","there","are","two","calponin","homology","domains",",","at","the","C-terminus","there","are","two","EF-hands",".","These","two","domains","are","connected","by","the","rod","domain",".","This","domain","is","formed","by","triple-helical","spectrin","repeats","."),4286074). assertion_content_comment('oboGo_AlphaAdrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","alpha-adrenergic","receptors","."),4197879). assertion_content_comment('oboGo_AlphaAgaraseactivity',s("Catalysis","of","the","endohydrolysis","of","1",",","3-alpha-L-galactosidic","linkages","in","agarose",",","yielding","agarotetraose","as","the","major","product","."),4344554). assertion_content_comment('oboGo_AlphaAlphaPhosphotrehalaseactivity',s("Catalysis","of","the","reaction",":","alpha",",","alpha-trehalose","6-phosphate","+","H2O","=","D-glucose","+","D-glucose","6-phosphate","."),4249044). assertion_content_comment('oboGo_AlphaAlphaTrehalaseactivity',s("Catalysis","of","the","reaction",":","alpha",",","alpha-trehalose","+","H2O","=","2","D-glucose","."),4204678). assertion_content_comment('oboGo_AlphaAlphaTrehalosePhosphatesynthasecomplexudpForming',s("A","protein","complex","that","possesses","alpha",",","alpha-trehalose-phosphate","synthase","(","UDP-forming",")","and","trehalose-phosphatase","activities",",","and","thus","catalyzes","two","reactions","in","trehalose","biosynthesis",".","In","the","complex","identified","in","Saccharomyces",",","Tps1p","has","alpha",",","alpha-trehalose-phosphate","synthase","(","UDP-forming",")","activity",",","Tps2p","has","trehalose","6-phosphate","phosphatase","activity",";","Tps3p","is","a","regulatory","subunit",",","and","an","additional","subunit",",","Tsl1p",",","may","be","present","."),4220760). assertion_content_comment('oboGo_AlphaAlphaTrehalosePhosphatesynthasegdpFormingactivity',s("Catalysis","of","the","reaction",":","GDP-D-glucose","+","glucose-6-phosphate","=","alpha",",","alpha-trehalose","6-phosphate","+","GDP","."),4367021). assertion_content_comment('oboGo_AlphaAlphaTrehalosePhosphatesynthaseudpFormingactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","D-glucose-6-phosphate","=","UDP","+","alpha",",","alpha-trehalose-6-phosphate","."),4188398). assertion_content_comment('oboGo_AlphaAlphaTrehalosephosphorylaseactivity',s("Catalysis","of","the","reaction",":","alpha",",","alpha-trehalose","+","phosphate","=","D-glucose","+","beta-D-glucose","1-phosphate","."),4372597). assertion_content_comment('oboGo_AlphaAlphaTrehalosephosphorylaseconfigurationRetainingactivity',s("Catalysis","of","the","reaction",":","alpha",",","alpha-trehalose","+","phosphate","=","alpha-D-glucose","+","alpha-D-glucose","1-phosphate","."),4343397). assertion_content_comment('oboGo_Alpha_Amino_3_Hydroxy_5_Methyl_4_IsoxazolePropionateSelectiveGlutamateReceptorActivity',s("An","ionotropic","glutamate","receptor","activity","that","exhibits","fast","gating","by","glutamate","and","acts","by","opening","a","cation","channel","permeable","to","sodium",",","potassium",",","and",",","in","the","absence","of","a","GluR2","subunit",",","calcium","."),4198046). assertion_content_comment('oboGo_Alpha_Amino_3_Hydroxy_5_Methyl_4_IsoxazolepropionicAcidSelectiveGlutamateReceptorComplex',s("An","assembly","of","four","or","five","subunits","which","form","a","structure","with","an","extracellular","N-terminus","and","a","large","loop","that","together","form","the","ligand","binding","domain",".","The","C-terminus","is","intracellular",".","The","ionotropic","glutamate","receptor","complex","itself","acts","as","a","ligand","gated","ion","channel",";","on","binding","glutamate",",","charged","ions","pass","through","a","channel","in","the","center","of","the","receptor","complex",".","The","AMPA","receptors","mediate","fast","synaptic","transmission","in","the","CNS","and","are","composed","of","subunits","GluR1-4",",","products","from","separate","genes",".","These","subunits","have","an","extracellular","N-terminus","and","an","intracellular","C-terminus","."),4329850). assertion_content_comment('oboGo_AlphaAminoAcidesteraseactivity',s("Catalysis","of","the","reaction",":","an","alpha-amino","acid","ester","+","H2O","=","an","alpha-amino","acid","+","an","alcohol","."),4372620). assertion_content_comment('oboGo_AlphaAminoadipateacetyltransferaseactivity',s("Catalysis","of","the","reaction",":","alpha-aminoadipate","+","acetyl-CoA","=","N2-acetyl-alpha-aminoadipate","+","coenzyme","A","."),4326674). assertion_content_comment('oboGo_AlphaAmylaseactivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-alpha-D-glucosidic","linkages","in","polysaccharides","containing","three","or","more","1",",","4-alpha-linked","D-glucose","units","."),4204699). assertion_content_comment('oboGo_AlphaAmylaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","alpha-amylase","."),4297075). assertion_content_comment('oboGo_AlphaAmyrinsynthaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-2",",","3-epoxysqualene","=","alpha-amyrin",".","This","reaction","is","a","cyclization","and","rearrangement","of","(","S",")","-2",",","3-epoxysqualene","(","2",",","3-oxidosqualene",")","into","alpha-amyrin","."),4316609). assertion_content_comment('oboGo_AlphaBetaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","an","alpha-beta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4378239). assertion_content_comment('oboGo_AlphaBetatcellactivationbysuperantigen',s("The","change","in","morphology","and","behavior","of","alpha-beta","T","cells","resulting","from","exposure","to","a","superantigen",",","a","microbial","antigen","with","an","extremely","potent","activating","effect","on","T","cells","that","bear","a","specific","variable","region","."),4316949). assertion_content_comment('oboGo_AlphaBetatcellactivationinvolvedinimmuneresponse',s("The","change","in","morphology","and","behavior","of","an","alpha-beta","T","cell","resulting","from","exposure","to","a","mitogen",",","cytokine",",","chemokine",",","cellular","ligand",",","or","an","antigen","for","which","it","is","specific",",","leading","to","the","initiation","or","perpetuation","of","an","immune","response","."),3992446). assertion_content_comment('oboGo_AlphaBetatcellactivation',s("The","change","in","morphology","and","behavior","of","an","alpha-beta","T","cell","resulting","from","exposure","to","a","mitogen",",","cytokine",",","chemokine",",","cellular","ligand",",","or","an","antigen","for","which","it","is","specific","."),3992441). assertion_content_comment('oboGo_AlphaBetatcelldifferentiationinvolvedinimmuneresponse',s("The","process","in","which","an","antigenically","naive","alpha-beta","T","cell","acquires","the","specialized","features","of","an","effector",",","regulatory",",","or","memory","T","cell","during","an","immune","response",".","Effector","T","cells","include","cells","which","provide","T","cell","help","or","exhibit","cytotoxicity","towards","other","cells","."),3992502). assertion_content_comment('oboGo_AlphaBetatcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","an","alpha-beta","T","cell",".","An","alpha-beta","T","cell","is","a","T","cell","that","expresses","an","alpha-beta","T","cell","receptor","complex","."),3992496). assertion_content_comment('oboGo_AlphaBetatcelllineagecommitment',s("The","process","in","which","a","pro-T","cell","becomes","committed","to","becoming","an","alpha-beta","T","cell","."),3994202). assertion_content_comment('oboGo_AlphaBetatcellproliferationinvolvedinimmuneresponse',s("The","expansion","of","an","alpha-beta","T","cell","population","by","cell","division","as","part","of","an","immune","response","."),4378414). assertion_content_comment('oboGo_AlphaBetatcellproliferation',s("The","expansion","of","an","alpha-beta","T","cell","population","by","cell","division","."),4098899). assertion_content_comment('oboGo_AlphaBetatcellreceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4306567). assertion_content_comment('oboGo_AlphaBetatcellreceptorcomplex',s("A","T","cell","receptor","complex","in","which","the","TCR","heterodimer","comprises","alpha","and","beta","chains",",","associated","with","the","CD3","complex",";","recognizes","a","complex","consisting","of","an","antigen-derived","peptide","bound","to","a","class","I","or","class","II","MHC","protein","."),4313765). assertion_content_comment('oboGo_AlphaBisabolenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","E",",","R",")","-alpha-bisabolene","+","diphosphate","."),4191460). assertion_content_comment('oboGo_AlphaCaroteneepsilonhydroxylaseactivity',s("Catalysis","of","the","reaction",":","alpha-carotene","+","NADPH","+","O2","+","H","+","=","alpha-cryptoxanthin","+","NADP","+","+","H2O","."),4159104). assertion_content_comment('oboGo_AlphaCateninbinding',s("Interacting","selectively","and","non-covalently","with","the","alpha","subunit","of","the","catenin","complex","."),4298717). assertion_content_comment('oboGo_AlphaDBeta2integrincomplex',s("An","integrin","complex","that","comprises","one","alphaD","subunit","and","one","beta2","subunit","."),4354753). assertion_content_comment('oboGo_AlphaDystroglycanbinding',s("Interacting","selectively","and","non-covalently","with","alpha-dystroglycan",".","Alpha-dystroglycan","is","extracellular","protein","derived","from","cleavage","of","dystroglycan","."),4375939). assertion_content_comment('oboGo_AlphaEBeta7integrincomplex',s("An","integrin","complex","that","comprises","one","alphaE","subunit","and","one","beta7","subunit","."),4354743). assertion_content_comment('oboGo_AlphaEBeta7integrinECadherincomplex',s("A","protein","complex","that","consists","of","an","alphaE-beta7","integrin","complex","bound","to","E-cadherin","."),4167292). assertion_content_comment('oboGo_AlphaFactorexport',s("OBSOLETE",".","The","directed","movement","of","alpha-factor",",","one","of","the","two","yeast","mating","factors",",","out","of","a","cell","."),4358995). assertion_content_comment('oboGo_AlphaFactorsexpheromoneexporter',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","alpha-factor","(","in",")","=","ADP","+","phosphate","+","alpha-factor","(","out",")","The","export","of","the","alpha-factor","sex","pheromone","by","an","ABC-type","(","ATP-binding","cassette-type",")","ATPase",",","characterized","by","the","presence","of","two","similar","ATP-binding","domains",",","that","does","not","undergo","phosphorylation","during","the","transport","process","."),4252523). assertion_content_comment('oboGo_AlphaFarnesenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","E",",","E",")","-alpha-farnesene","+","diphosphate","."),4186498). assertion_content_comment('oboGo_AlphaGalactosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","alpha-D-galactose","residues","in","alpha-D-galactosides",",","including","galactose","oligosaccharides",",","galactomannans","and","galactohydrolase","."),4204714). assertion_content_comment('oboGo_AlphaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","alpha-glucans",",","compounds","composed","of","glucose","residues","linked","by","alpha-D-glucosidic","bonds","."),4063849). assertion_content_comment('oboGo_AlphaGlucancatabolicprocessinvolvedinascosporereleasefromascus',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","alpha-glucans","in","the","ascus","wall","that","contributes","to","the","release","of","ascospores","from","the","ascus","."),4158609). assertion_content_comment('oboGo_AlphaGlucancatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","alpha-glucans","."),4158603). assertion_content_comment('oboGo_AlphaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","alpha-glucans",",","compounds","composed","of","glucose","residues","linked","by","alpha-D-glucosidic","bonds","."),4063846). assertion_content_comment('oboGo_AlphaGlucanwaterdikinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","alpha-glucan","+","H2O","=","AMP","+","phospho-alpha-glucan","+","phosphate","."),4269332). assertion_content_comment('oboGo_AlphaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","1",",","4-linked","alpha-D-glucose","residues","with","release","of","alpha-D-glucose","."),4204348). assertion_content_comment('oboGo_AlphaGlucosidaseiicomplex',s("A","heterodimeric","complex","that","catalyzes","the","trimming","of","glucose","residues","from","N-linked","core","glycans","on","newly","synthesized","glycoproteins","."),4258271). assertion_content_comment('oboGo_AlphaGlucoside_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","alpha-glucoside","(","out",")","+","H","+","(","out",")","=","alpha-glucoside","(","in",")","+","H","+","(","in",")","Alpha-glucosides","include","trehalose",",","maltose",",","turanose",",","isomaltose",",","alpha-methylglucoside",",","maltotriose",",","palatinose",",","trehalose","and","melezitose","."),4216528). assertion_content_comment('oboGo_AlphaGlucosidetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","alpha-glucosides","from","one","side","of","the","membrane","to","the","other",".","Alpha-glucosides","are","glycosides","in","which","the","sugar","group","is","a","glucose","residue",",","and","the","anomeric","carbon","of","the","bond","is","in","an","alpha","configuration","."),4216526). assertion_content_comment('oboGo_AlphaGlucosidetransport',s("The","directed","movement","of","alpha-glucosides","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Alpha-glucosides","are","glycosides","in","which","the","sugar","group","is","a","glucose","residue",",","and","the","anomeric","carbon","of","the","bond","is","in","an","alpha","configuration","."),4157419). assertion_content_comment('oboGo_AlphaGlucuronidaseactivity',s("Catalysis","of","the","reaction",":","an","alpha-D-glucuronoside","+","H2O","=","an","alcohol","+","D-glucuronate","."),4358732). assertion_content_comment('oboGo_AlphaHeterochromatin',s("A","small",",","compact","region","of","heterochromatin","located","in","the","middle","of","the","polytene","chromosome","chromocenter",",","which","undergoes","little","or","no","replication","during","polytenization","."),4007871). assertion_content_comment('oboGo_AlphaHumulenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","alpha-humulene","+","diphosphate","."),4182203). assertion_content_comment('oboGo_AlphaIIbBeta3integrinCd47Fakcomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","the","cell","surface","antigen","CD47","and","the","kinase","FAK","."),4176385). assertion_content_comment('oboGo_AlphaIIbBeta3integrinCd47Srccomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","the","cell","surface","antigen","CD47","and","the","kinase","c-Src","."),4176396). assertion_content_comment('oboGo_AlphaIIbBeta3integrinCd9Cd47Plateletglycoproteinibcomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","the","cell","surface","proteins","CD9","and","CD47",",","and","the","heterodimeric","platelet","glycoprotein","Ib","."),4166985). assertion_content_comment('oboGo_AlphaIIbBeta3integrinCd9complex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","the","cell","surface","protein","CD9","."),4166996). assertion_content_comment('oboGo_AlphaIIbBeta3integrinCibcomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","CIB",",","a","protein","that","binds","calcium","as","well","as","the","alphaIIb-beta3","integrin","."),4176296). assertion_content_comment('oboGo_AlphaIIbBeta3integrincomplex',s("An","integrin","complex","that","comprises","one","alphaIIb","subunit","and","one","beta3","subunit","."),4175402). assertion_content_comment('oboGo_AlphaIIbBeta3integrinFibronectinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","fibronectin","and","tissue","transglutaminase","."),4166840). assertion_content_comment('oboGo_AlphaIIb_Beta3Integrin_ICAM_4Complex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","the","cell","adhesion","molecule","ICAM-4","."),4164343). assertion_content_comment('oboGo_AlphaIIbBeta3integrinTalincomplex',s("A","protein","complex","that","consists","of","an","alphaIIb-beta3","integrin","complex","bound","to","talin","."),4174964). assertion_content_comment('oboGo_AlphaKetoaciddehydrogenaseactivity',s("Catalysis","of","an","oxidation-reduction","(","redox",")","reaction","involving","an","alpha-ketoacid","."),4188427). assertion_content_comment('oboGo_AlphaKetoamidereductaseactivity',s("Catalysis","of","the","reaction",":","alpha-keto","amide","+","2","H","+","(","from","donor",")","=","(","R",")","-hydroxy","amide",".","Alpha-keto","amides","are","of","the","form","R-CO-CONH2",",","where","R","may","be","aromatic","or","aliphatic","."),4285777). assertion_content_comment('oboGo_AlphaKetoesterreductaseactivity',s("Catalysis","of","the","reaction",":","alpha-keto","ester","+","2","H","+","(","from","donor",")","=","(","R",")","-hydroxy","ester",".","Alpha-keto","esters","are","of","the","form","R","(","1",")","-CO-CO-O-R","(","2",")",",","where","the","R","groups","may","be","aromatic","or","aliphatic","."),4285741). assertion_content_comment('oboGo_AlphaKetoglutarate_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","alpha-ketoglutarate","(","out",")","+","H","+","(","out",")","=","alpha-ketoglutarate","(","in",")","+","H","+","(","in",")"),4293198). assertion_content_comment('oboGo_AlphaKetoglutaratetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","alpha-ketoglutarate","from","one","side","of","the","membrane","to","the","other",".","Alpha-ketoglutarate","(","or","oxoglutarate",")","is","a","compound","with","important","roles","in","carbohydrate","and","amino","acid","metabolism",",","especially","in","transamination","reactions","and","as","a","component","of","the","TCA","cycle","."),4293193). assertion_content_comment('oboGo_AlphaKetoglutaratetransport',s("The","directed","movement","of","alpha-ketoglutarate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4228498). assertion_content_comment('oboGo_AlphaLBeta2integrincomplex',s("An","integrin","complex","that","comprises","one","alphaL","subunit","and","one","beta2","subunit","."),4354662). assertion_content_comment('oboGo_AlphaLFucosidaseactivity',s("Catalysis","of","the","reaction",":","an","alpha-L-fucoside","+","H2O","=","an","alcohol","+","L-fucose","."),4204619). assertion_content_comment('oboGo_AlphaLRhamnosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","alpha-L-rhamnose","residues","in","alpha-L-rhamnosides","."),4307825). assertion_content_comment('oboGo_AlphaMannosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","alpha-D-mannose","residues","in","alpha-D-mannosides","."),4204520). assertion_content_comment('oboGo_AlphaMBeta2integrinCd63complex',s("A","protein","complex","that","consists","of","an","alphaM-beta2","integrin","complex","bound","to","membrane","protein","CD63",",","a","member","of","the","tetraspan","family","."),4174748). assertion_content_comment('oboGo_AlphaMBeta2integrincomplex',s("An","integrin","complex","that","comprises","one","alphaM","subunit","and","one","beta2","subunit","."),4354692). assertion_content_comment('oboGo_AlphaMethylacylCoaracemaseactivity',s("Catalysis","of","the","reaction",":","(","2S",")","-2-methylacyl-CoA","=","(","2R",")","-2-methylacyl-CoA","."),4246241). assertion_content_comment('oboGo_AlphaMitochondrialprocessingpeptidase',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4210226). assertion_content_comment('oboGo_AlphaNAcetylgalactosaminidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","N-acetyl-D-galactosamine","residues","in","N-acetyl-alpha-D-galactosaminides","."),4253883). assertion_content_comment('oboGo_Alpha_N_AcetylgalactosaminideAlpha_26_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","glycano-1",",","3-","(","N-acetyl-alpha-D-galactosaminyl",")","-glycoprotein","=","CMP","+","glycano-","(","2",",","6-alpha-N-acetylneuraminyl",")","-","(","N-acetyl-D-galactosaminyl",")","-glycoprotein","."),4384107). assertion_content_comment('oboGo_AlphaNAcetylglucosaminidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","N-acetyl-D-glucosamine","residues","in","N-acetyl-alpha-D-glucosaminides","."),4204630). assertion_content_comment('oboGo_Alpha_N_AcetylneuraminateAlpha_28_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-R","=","CMP","+","alpha-N-acetylneuraminyl-2",",","8-alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-R","."),4188465). assertion_content_comment('oboGo_Alpha_N_Acetylneuraminyl_23_Beta_Galactosyl_13_N_Acetyl_Galactosaminide6_Alpha_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-N-acetylneuraminyl-","(","2-","&","gt",";","3",")","-beta-D-galactosyl-","(","1-","&","gt",";","3",")","-N-acetyl-D-galactosaminyl-R","+","CMP-N-acetyl-beta-neuraminate","=","alpha-N-acetylneuraminyl-","(","2-","&","gt",";","3",")","-beta-D-galactosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-alpha-neuraminyl-","(","2-","&","gt",";","6",")","]","-N-acetyl-D-galactosaminyl-R","+","CMP","."),4367708). assertion_content_comment('oboGo_AlphaNArabinofuranosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","alpha-L-arabinofuranoside","residues","in","alpha-L-arabinosides","."),4359079). assertion_content_comment('oboGo_AlphaNeoagaroOligosaccharidehydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","the","1",",","3-alpha-L-galactosidic","linkages","of","neoagaro-oligosaccharides","that","are","smaller","than","a","hexamer",",","yielding","3",",","6-anhydro-L-galactose","and","D-galactose","."),4344542). assertion_content_comment('oboGo_AlphaPDGFR_PLC_Gamma_1_PI3K_SHP_2Complex',s("A","protein","complex","that","contains","the","platelet-derived","growth","factor","alpha","receptor","(","alphaPDGFR",";","PDGFRA",")",",","phospholipase","C-gamma-1","(","PLC-gamma-1",")",",","phosphatidylinositol","3-kinase","(","PI3K",")","and","the","adaptor","protein","SHP-2",",","and","is","involved","signaling","via","the","PDGFR","signaling","pathway","."),4176717). assertion_content_comment('oboGo_AlphaPDGFR_SHP_2Complex',s("A","protein","complex","that","contains","the","platelet-derived","growth","factor","alpha","receptor","(","alphaPDGFR",";","PDGFRA",")","and","the","adaptor","protein","SHP-2",",","and","is","involved","signaling","via","the","PDGFR","signaling","pathway","."),4176706). assertion_content_comment('oboGo_AlphaPinenebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","alpha-pinene",",","a","monoterpene","that","may","be","a","significant","factor","affecting","bacterial","activities","in","nature","."),4353491). assertion_content_comment('oboGo_AlphaPinenecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","alpha-pinene",",","a","monoterpene","that","may","be","a","significant","factor","affecting","bacterial","activities","in","nature","."),4353477). assertion_content_comment('oboGo_AlphaPinenedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","alpha-pinene","+","O2","+","2","H","+","+","2","e-","=","H2O","+","myrtenol","."),4276943). assertion_content_comment('oboGo_AlphaPinenelyaseactivity',s("Catalysis","of","the","reaction",":","alpha-pinene","=","limonene","."),4273860). assertion_content_comment('oboGo_AlphaPinenemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","alpha-pinene",",","a","monoterpene","that","may","be","a","significant","factor","affecting","bacterial","activities","in","nature",".","It","is","a","major","component","in","tea-tree","oils",",","and","gives","off","a","piney","smelling","odor","."),4273234). assertion_content_comment('oboGo_AlphaPinenemonooxygenaseactivity',s("Catalysis","of","the","reaction",":","alpha-pinene","+","O2","+","2","H","+","+","2","e-","=","H2O","+","pinocarveol","."),4275558). assertion_content_comment('oboGo_AlphaPinenemonooxygenasenadhactivity',s("Catalysis","of","the","reaction",":","alpha-pinene","+","NADH","+","H","+","+","O2","=","NAD","+","+","H2O","+","alpha-pinene","oxide","."),4275922). assertion_content_comment('oboGo_AlphaPineneOxidedecyclaseactivity',s("Catalysis","of","the","reaction",":","alpha-pinene","oxide","=","(","Z",")","-2-methyl-5-isopropylhexa-2",",","5-dienal","."),4273697). assertion_content_comment('oboGo_AlphaRibazolephosphataseactivity',s("Catalysis","of","the","reaction",":","alpha-ribazole","5","'","-phosphate","+","H","(","2",")","O","=","alpha-ribazole","+","phosphate","."),4326129). assertion_content_comment('oboGo_AlphaSantonin12Reductaseactivity',s("Catalysis","of","the","reaction",":","1",",","2-dihydrosantonin","+","NAD","(","P",")","+","=","alpha-santonin","+","NAD","(","P",")","H","+","H","+"),4372572). assertion_content_comment('oboGo_AlphaSialidaseactivity',s("Catalysis","of","the","hydrolysis","of","alpha-glycosidic","linkages","in","oligo-","or","poly","(","sialic",")","acids","."),4208728). assertion_content_comment('oboGo_AlphaTubulinacetylation',s("The","addition","of","an","acetyl","group","to","the","lysine","40","residue","of","alpha-tubulin","."),4167921). assertion_content_comment('oboGo_AlphaTubulinbinding',s("Interacting","selectively","and","non-covalently","with","the","microtubule","constituent","protein","alpha-tubulin","."),4318048). assertion_content_comment('oboGo_AlphavBeta1integrincomplex',s("An","integrin","complex","that","comprises","one","alphav","subunit","and","one","beta1","subunit","."),4354632). assertion_content_comment('oboGo_AlphavBeta1integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alphav-beta1","integrin","complex","bound","to","osteopontin","."),4180367). assertion_content_comment('oboGo_AlphavBeta3integrinAdam15complex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM15","."),4167314). assertion_content_comment('oboGo_AlphavBeta3integrinAdam23complex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","the","transmembrane","metallopeptidase","ADAM23","."),4166963). assertion_content_comment('oboGo_AlphavBeta3integrinCd47complex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","CD47","(","also","known","as","IAP",")"),4173417). assertion_content_comment('oboGo_AlphaVBeta3integrinCd47Fcer2complex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","the","cell","surface","protein","CD47","and","the","low-affinity","immunoglobulin","epsilon","Fc","receptor","(","FCER2",")"),4167062). assertion_content_comment('oboGo_AlphaVBeta3integrinCd98complex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","the","cell","surface","antigen","CD98","."),4164598). assertion_content_comment('oboGo_AlphavBeta3integrinCollagenalpha3vicomplex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","the","alpha3","chain","of","type","VI","collagen",";","the","integrin","binds","most","strongly","to","unfolded","collagen","."),4175981). assertion_content_comment('oboGo_AlphavBeta3integrincomplex',s("An","integrin","complex","that","comprises","one","alphav","subunit","and","one","beta3","subunit","."),4354622). assertion_content_comment('oboGo_AlphaVBeta3integrinEgfrcomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","epidermal","growth","factor","receptor","."),4164664). assertion_content_comment('oboGo_AlphaVBeta3integrinGelsolincomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","gelsolin","."),4166818). assertion_content_comment('oboGo_AlphaV_Beta3Integrin_LamininAlpha_4Complex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","laminin","alpha-4","."),4164620). assertion_content_comment('oboGo_AlphaVBeta3integrinLpp3complex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","lipid","phosphate","phosphohydrolase-3","."),4164708). assertion_content_comment('oboGo_AlphaVBeta3integrinNovcomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","the","extracellular","matrix","protein","NOV","."),4164288). assertion_content_comment('oboGo_AlphavBeta3integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","osteopontin","."),4180445). assertion_content_comment('oboGo_AlphaVBeta3integrinPaxillinPyk2complex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","paxillin","and","the","FAK-related","kinase","Pyk2","."),4166807). assertion_content_comment('oboGo_AlphavBeta3integrinThrombospondincomplex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","thrombospondin","."),4180324). assertion_content_comment('oboGo_AlphaVBeta3integrinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","tissue","transglutaminase","."),4166851). assertion_content_comment('oboGo_AlphaVBeta3integrinTumstatincomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta3","integrin","complex","bound","to","tumstatin",",","the","NC1","domain","of","the","alpha3","chain","of","type","IV","collagen","."),4164332). assertion_content_comment('oboGo_AlphavBeta3integrinVitronectincomplex',s("A","protein","complex","that","consists","of","an","alphav-beta3","integrin","complex","bound","to","vitronectin","."),4167281). assertion_content_comment('oboGo_AlphavBeta5integrincomplex',s("An","integrin","complex","that","comprises","one","alphav","subunit","and","one","beta5","subunit","."),4354652). assertion_content_comment('oboGo_AlphavBeta5integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alphav-beta5","integrin","complex","bound","to","osteopontin","."),4180389). assertion_content_comment('oboGo_AlphavBeta5integrinVitronectincomplex',s("A","protein","complex","that","comprises","one","integrin","alphav","subunit",",","one","integrin","beta5","subunit",",","and","vitronectin","."),4072355). assertion_content_comment('oboGo_AlphavBeta6integrincomplex',s("An","integrin","complex","that","comprises","one","alphav","subunit","and","one","beta6","subunit","."),4354642). assertion_content_comment('oboGo_AlphaVBeta6integrinOsteopontincomplex',s("A","protein","complex","that","consists","of","an","alphaV-beta6","integrin","complex","bound","to","osteopontin","."),4164697). assertion_content_comment('oboGo_AlphaV_Beta6Integrin_TGFbeta_3Complex',s("A","protein","complex","that","consists","of","an","alphaV-beta6","integrin","complex","bound","to","transforming","growth","factor","beta-3","(","TGFbeta-3",")"),4166785). assertion_content_comment('oboGo_AlphavBeta8integrincomplex',s("An","integrin","complex","that","comprises","one","alphav","subunit","and","one","beta8","subunit","."),4354672). assertion_content_comment('oboGo_AlphaV_Beta8Integrin_MMP14_TGFbeta_1Complex',s("A","protein","complex","that","consists","of","an","alphaV-beta8","integrin","complex","bound","to","matrix","metalloproteinase","14","and","transforming","growth","factor","beta-1","(","TGFbeta-1",")"),4164481). assertion_content_comment('oboGo_AlphaXBeta2integrincomplex',s("An","integrin","complex","that","comprises","one","alphaX","subunit","and","one","beta2","subunit","."),4354682). assertion_content_comment('oboGo_AlphaX_Beta2Integrin_ICAM_4Complex',s("A","protein","complex","that","consists","of","an","alphaX-beta2","integrin","complex","bound","to","intercellular","adhesion","molecule","4","."),4164631). assertion_content_comment('oboGo_AlternativeComplementPathwayc3c5convertaseactivity',s("OBSOLETE",".","Catalysis","of","the","cleavage","of","Arg-Ser","bond","in","complement","component","C3","alpha-chain","to","yield","C3a","and","C3b",",","and","Arg","bond","in","complement","component","C5","alpha-chain","to","yield","C5a","and","C5b","."),4187741). assertion_content_comment('oboGo_AmideTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","amide","(","out",")","=","ADP","+","phosphate","+","amide","(","in",")"),4338163). assertion_content_comment('oboGo_AmidineLyaseactivity',s("Catalysis","of","the","release","of","amides","or","amidines","by","the","cleavage","of","a","carbon-nitrogen","bond","or","the","reverse","reaction","with","an","amide","or","amidine","as","a","substrate","."),4177033). assertion_content_comment('oboGo_AmineLyaseactivity',s("Catalysis","of","the","release","of","amides","by","the","cleavage","of","a","carbon-nitrogen","bond","or","the","reverse","reaction","with","an","amine","as","a","substrate","."),4268186). assertion_content_comment('oboGo_AmineNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","an","amine","=","S-adenosyl-L-homocysteine","+","a","methylated","amine","."),4308705). assertion_content_comment('oboGo_AmineTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","amine","(","out",")","=","ADP","+","phosphate","+","amine","(","in",")"),4289753). assertion_content_comment('oboGo_AminoAcidExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","amino","acid","(","in",")","=","ADP","+","phosphate","+","amino","acid","(","out",")"),4331490). assertion_content_comment('oboGo_AminoAcidImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","amino","acid","(","out",")","=","ADP","+","phosphate","+","amino","acid","(","in",")"),4331449). assertion_content_comment('oboGo_AminoAcidracemaseactivity',s("Catalysis","of","the","reaction",":","an","L-amino","acid","=","a","D-amino","acid","."),4249164). assertion_content_comment('oboGo_AminoAcidTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","amino","acid","(","out/in",")","=","ADP","+","phosphate","+","amino","acid","(","in/out",")"),4289756). assertion_content_comment('oboGo_AminoacylTrnaeditingactivity',s("The","hydrolysis","of","an","incorrectly","aminoacylated","tRNA","."),4328704). assertion_content_comment('oboGo_AminoacylTrnahydrolaseactivity',s("Catalysis","of","the","reaction",":","N-substituted","aminoacyl-tRNA","+","H2O","=","N-substituted","amino","acid","+","tRNA","."),4213463). assertion_content_comment('oboGo_AminoacylTrnahydrolasereaction',s("OBSOLETE",".","Hydrolysis","of","the","peptidyl-tRNA","by","aminoacyl-tRNA","hydrolase","upon","termination","of","translation",".","Analogous","to","usual","peptidyl","transfer","during","elongation",",","except","that","the","acceptor","is","H2O","instead","of","an","aminoacyl-tRNA","."),4223869). assertion_content_comment('oboGo_AminoacylTrnaligaseactivity',s("Catalysis","of","the","formation","of","aminoacyl-tRNA","from","ATP",",","amino","acid",",","and","tRNA","with","the","release","of","diphosphate","and","AMP","."),4199084). assertion_content_comment('oboGo_AminoacylTrnasynthetasemultienzymecomplex',s("A","multienzyme","complex","found","in","all","multicellular","eukaryotes","composed","of","eight","proteins","with","aminoacyl-tRNA","synthetase","activities","(","abbreviated","as",":","ArgRS",",","AspRS",",","GluProRS",",","GlnRS",",","IleRS",",","LeuRS",",","LysRS",",","MetRS","where","RS","is","the","enzyme",",","preceded","by","the","amino","acid","it","uses","as","a","substrate",")","as","well","as","three","non-synthetase","proteins","(","p43",",","p38",",","and","p18",")","with","diverse","functions",".","Several","of","these","subunits","are","known","dimers",",","so","the","total","polypeptide","count","in","the","multisynthetase","complex","is","at","least","fifteen",".","All","of","the","enzymes","in","this","assembly","catalyze","the","same","reaction",",","the","covalent","attachment","of","an","amino","acid","to","either","the","2","'","-","or","3","'","-hydroxyl","of","the","3","'","-terminal","adenosine","of","tRNA",",","but","using","different","substrates","."),4267666). assertion_content_comment('oboGo_AminoadipateSemialdehydedehydrogenasecomplex',s("OBSOLETE",".","A","heterodimeric","enzyme","composed","of","an","alpha","and","beta","subunit",".","Catalyzes","the","formation","of","L-2-aminoadipate","from","L-2-aminoadipate","6-semialdehyde","."),4221141). assertion_content_comment('oboGo_AminocarboxymuconateSemialdehydedecarboxylaseactivity',s("Catalysis","of","the","reaction",":","2-amino-3-carboxymuconate","6-semialdehyde","+","H","(","+",")","=","2-aminomuconate","6-semialdehyde","+","CO","(","2",")"),4383470). assertion_content_comment('oboGo_Aminoglycoside1NAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","aminoglycoside","=","CoA","+","1-N-acetylaminoglycoside",".","This","is","acetylation","of","the","1-amino","group","of","the","central","deoxystreptamine","ring","."),4361180). assertion_content_comment('oboGo_Aminoglycoside2NAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","gentamicin","C","(","1a",")","=","N","(","2","'",")","-acetylgentamicin","C","(","1a",")","+","CoA","+","H","(","+",")","This","is","acetylation","of","the","2","'","-amino","group","of","the","6-deoxy-6-aminoglucose","ring","."),4378075). assertion_content_comment('oboGo_Aminoglycoside2Nucleotidyltransferaseactivity',s("Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","aminoglycoside","=","diphosphate","+","2","'","'","-nucleotidylaminoglycoside","."),4249737). assertion_content_comment('oboGo_Aminoglycoside3Adenylyltransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","streptomycin","=","3","'","'","-adenylylstreptomycin","+","diphosphate","+","H","(","+",")"),4256595). assertion_content_comment('oboGo_Aminoglycoside3NAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","aminoglycoside","=","CoA","+","3-N-acetylaminoglycoside",".","This","is","acetylation","of","the","3-amino","group","of","the","central","deoxystreptamine","ring","."),4350054). assertion_content_comment('oboGo_Aminoglycoside6Kinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","streptomycin","=","ADP","+","2","H","(","+",")","+","streptomycin","6-phosphate","."),4265760). assertion_content_comment('oboGo_Aminoglycoside6NAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","kanamycin","B","=","N","(","6","'",")","-acetylkanamycin","B","+","CoA","+","H","(","+",")","This","is","acetylation","of","the","6","'","-amino","group","of","the","6-deoxy-6-aminoglucose","ring","."),4372545). assertion_content_comment('oboGo_AminoglycosideNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","aminoglycoside","=","CoA","+","N-acetylaminoglycoside","."),4350051). assertion_content_comment('oboGo_AminomuconateSemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","NAD","+","+","2-aminomuconate","semialdehyde","=","NADH","+","2-amino-muconate","."),4365983). assertion_content_comment('oboGo_AminoTerminalvacuolarsortingpropeptidebinding',s("Interacting","selectively","and","non-covalently","with","an","amino","terminal","propeptide",",","which","functions","as","a","sorting","signal","to","sort","away","the","soluble","vacuolar","protein","from","Golgi","to","lytic","vacuole","via","clathrin","coated","vesicles","."),4261776). assertion_content_comment('oboGo_AmmoniaLyaseactivity',s("Catalysis","of","the","release","of","ammonia","by","the","cleavage","of","a","carbon-nitrogen","bond","or","the","reverse","reaction","with","ammonia","as","a","substrate","."),4185842). assertion_content_comment('oboGo_Amorpha_411_DieneSynthaseActivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","amorpha-4",",","11-diene","+","diphosphate","."),4360583). assertion_content_comment('oboGo_AMPActivatedproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","presence","of","AMP","."),4202375). assertion_content_comment('oboGo_AMPActivatedproteinkinasecomplex',s("A","protein","complex","that","possesses","AMP-dependent","protein","kinase","activity","."),4322210). assertion_content_comment('oboGo_AMPThymidinekinaseactivity',s("Catalysis","of","the","reaction",":","AMP","+","thymidine","=","adenosine","+","thymidine","5","'","-phosphate","."),4372477). assertion_content_comment('oboGo_AmygdalinBetaGlucosidaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-amygdalin","+","H","(","2",")","O","=","(","R",")","-prunasin","+","D-glucose","."),4372461). assertion_content_comment('oboGo_Amylo_Alpha_16_GlucosidaseActivity',s("Catalysis","of","the","hydrolysis","of","(","1",",","6",")","-alpha-D-glucosidic","branch","linkages","in","glycogen","phosphorylase","limit","dextrin",".","Limit","dextrin","is","the","highly","branched","core","that","remains","after","exhaustive","treatment","of","glycogen","with","glycogen","phosphorylase",".","It","is","formed","because","these","enzymes","cannot","hydrolyze","the","1",",","6","glycosidic","linkages","present","."),4211801). assertion_content_comment('oboGo_Anaerobic111_Trichloro_22_Bis_4_ChlorophenylEthaneMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","1",",","1",",","1-trichloro-2",",","2-bis-","(","4-chlorophenyl",")","ethane","(","DDT",")",",","a","chlorinated",",","broad","spectrum",",","contact","insecticide",",","in","the","absence","of","oxygen","."),4272599). assertion_content_comment('oboGo_Anaerobic246Trinitrotoluenebiosyntheticprocess',s("OBSOLETE",".","The","chemical","reactions","and","pathways","resulting","in","the","formation","of","2",",","4",",","6-trinitrotoluene",",","1-methyl-2",",","4",",","6-trinitrobenzene",",","a","highly","explosive","pale","yellow","crystalline","solid",",","in","the","absence","of","oxygen","."),4353597). assertion_content_comment('oboGo_Anaerobic246Trinitrotoluenecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","2",",","4",",","6-trinitrotoluene",",","1-methyl-2",",","4",",","6-trinitrobenzene",",","a","highly","explosive","pale","yellow","crystalline","solid",",","in","the","absence","of","oxygen","."),4353612). assertion_content_comment('oboGo_Anaerobic246Trinitrotoluenemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","2",",","4",",","6-trinitrotoluene",",","1-methyl-2",",","4",",","6-trinitrobenzene",",","a","highly","explosive","pale","yellow","crystalline","solid",",","that","occur","in","the","absence","of","oxygen","."),4272573). assertion_content_comment('oboGo_Anaerobic2Aminobenzoatemetabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","2-aminobenzoate",",","a","derivative","of","benzoic","acid","with","an","NH2","group","attached","to","C2",",","that","occurs","in","the","absence","of","oxygen","."),4273201). assertion_content_comment('oboGo_AnaerobicCyclohexane_1_CarboxylateCatabolicProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","cyclohexane-1-carboxylate",",","a","alicyclic","acid",",","in","the","absence","of","oxygen","."),4334431). assertion_content_comment('oboGo_AnaerobicGlycerolCatabolicProcessToPropane_13_Diol',s("The","anaerobic","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glycerol","into","propane-1",",","3-diol","and","water","."),4243185). assertion_content_comment('oboGo_AnaerobicLAlaninecatabolicprocess',s("The","anaerobic","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-alanine",",","yielding","energy","in","the","form","of","ATP","."),4244456). assertion_content_comment('oboGo_AnaerobicPhenolContainingcompoundbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","absence","of","oxygen","."),4351776). assertion_content_comment('oboGo_AnaerobicPhenolContainingcompoundcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","absence","of","oxygen","."),4351820). assertion_content_comment('oboGo_AnaerobicPhenolContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","phenol",",","any","compound","containing","one","or","more","hydroxyl","groups","directly","attached","to","an","aromatic","carbon","ring",",","in","the","absence","of","oxygen","."),4314257). assertion_content_comment('oboGo_AnaerobicRibonucleosideTriphosphatereductasecomplex',s("An","enzyme","complex","composed","of","4","subunits",",","2","copies","of","the","large","protein","(","nrdD","in","E",".","coli",")","and","2","copies","of","the","small","protein","(","nrdG","in","E",".","coli",")","It","catalyzes","the","generation","of","2","'","deoxyribonucleotides","under","anaerobic","growth","conditions",".","The","larger","subunit","is","the","catalytic","unit","that","is","activated","by","the","smaller","iron-binding","subunit","."),4320057). assertion_content_comment('oboGo_AnaphasePromotingcomplexbinding',s("Interacting","selectively","and","non-covalently","with","an","anaphase-promoting","complex",".","A","ubiquitin","ligase","complex","that","degrades","mitotic","cyclins","and","anaphase","inhibitory","protein",",","thereby","triggering","sister","chromatid","separation","and","exit","from","mitosis","."),4336846). assertion_content_comment('oboGo_AnaphasePromotingcomplexDependentproteasomalubiquitinDependentproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","protein","or","peptide","by","hydrolysis","of","its","peptide","bonds",",","initiated","by","the","covalent","attachment","of","ubiquitin",",","with","ubiquitin-protein","ligation","catalyzed","by","the","anaphase-promoting","complex",",","and","mediated","by","the","proteasome","."),4012087). assertion_content_comment('oboGo_AnaphasePromotingcomplex',s("A","ubiquitin","ligase","complex","that","degrades","mitotic","cyclins","and","anaphase","inhibitory","protein",",","thereby","triggering","sister","chromatid","separation","and","exit","from","mitosis",".","Substrate","recognition","by","APC","occurs","through","degradation","signals",",","the","most","common","of","which","is","termed","the","Dbox","degradation","motif",",","originally","discovered","in","cyclin","B","."),4220472). assertion_content_comment('oboGo_Androst_4_Ene_317_DioneMonooxygenaseActivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","androst-4-ene-3",",","17-dione","+","O","(","2",")","=","A","+","H","(","2",")","O","+","testololactone","."),4364621). assertion_content_comment('oboGo_Androstan_3_Alpha17_Beta_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","NAD","+","+","androstan-3-alpha",",","17-beta-diol","=","17-beta-hydroxyandrostan-3-one","+","NADH","+","H","+"),4364204). assertion_content_comment('oboGo_AndrosteroneDehydrogenaseASpecificactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","androsterone","=","NAD","(","P",")","H","+","H","+","+","5-alpha-androstane-3",",","17-dione",".","The","reaction","is","A-specific","(","i.e",".","the","pro-R","hydrogen","is","transferred","from","the","4-position","of","reduced","nicotinamide","cofactor",")","with","respect","to","NAD","(","P",")","+"),4363973). assertion_content_comment('oboGo_AndrosteroneDehydrogenaseBSpecificactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","androsterone","=","NAD","(","P",")","H","+","H","+","+","5-alpha-androstane-3",",","17-dione",".","The","reaction","is","B-specific","(","i.e",".","the","pro-S","hydrogen","is","transferred","from","the","4-position","of","reduced","nicotinamide","cofactor",")","with","respect","to","NAD","(","P",")","+"),4364174). assertion_content_comment('oboGo_AnesthesiaResistantmemory',s("The","memory","process","that","results","in","the","formation","of","consolidated","memory","resistant","to","disruption","of","the","patterned","activity","of","the","brain",",","without","requiring","protein","synthesis","."),4234934). assertion_content_comment('oboGo_AngiogeninPricomplex',s("A","stable","heterodimer","of","angiogenin","and","placental","ribonuclease","inhibitor",";","interaction","between","angiogenin","and","PRI","prevents","angiogenin","binding","to","its","receptor","to","stimulate","angiogenesis","."),4333876). assertion_content_comment('oboGo_AngiotensinConvertingenzymeinhibitoractivity',s("OBSOLETE",".","Stops",",","prevents","or","reduces","the","activity","of","angiotensin-converting","enzyme",",","thereby","preventing","the","synthesis","of","angiotensin","II","from","its","precursor",",","angiotensin","I","."),4306319). assertion_content_comment('oboGo_AngiotensinMediateddrinkingbehavior',s("The","drinking","behavior","that","is","mediated","by","the","action","of","angiotensin","in","the","brain",".","Angiotensin","stimulates","the","brain","centers","that","control","thirst","."),3999150). assertion_content_comment('oboGo_AnionTransmembraneTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","anion","(","out",")","=","ADP","+","phosphate","+","anion","(","in",")"),4291381). assertion_content_comment('oboGo_AnkyrinRepeatMediatedcomplexassembly',s("A","process","of","protein","complex","assembly","in","which","the","arrangement","and","bonding","together","of","the","set","of","components","that","form","the","protein","complex","is","mediated","by","an","ankyrin","repeat","interaction","."),4172037). assertion_content_comment('oboGo_Anthocyanidin_3_GlucosideRhamnosyltransferaseActivity',s("Catalysis","of","the","reaction",":","anthocyanidin","3-glucoside","+","UDP-rhamnose","=","anthocyanidin","3-rutinoside","+","UDP","."),4284038). assertion_content_comment('oboGo_Anthocyanidin3OGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","anthocyanidin","+","UDP-D-glucose","=","anthocyanidin-3-O-D-glucoside","+","UDP","."),4366642). assertion_content_comment('oboGo_Anthocyanin3OBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","an","anthocyanin","=","UDP","+","an","anthocyanin","3","'","-O-beta-D-glucoside","."),4343342). assertion_content_comment('oboGo_Anthocyanin5Aromaticacyltransferaseactivity',s("Catalysis","of","the","reaction",":","anthocyanidin-3",",","5-diglucoside","+","hydroxycinnamoyl-CoA","=","anthocyanidin","3-glucoside-5-hydroxycinnamoylglucoside","+","CoA","."),4366240). assertion_content_comment('oboGo_Anthocyanin5OGlucoside6OMalonyltransferaseactivity',s("Catalysis","of","the","reaction",":","malonyl-CoA","+","pelargonidin","3-O-","(","6-caffeoyl-beta-D-glucoside",")","5-O-beta-D-glucoside","=","CoA","+","4","'","'","'","-demalonylsalvianin","."),4343053). assertion_content_comment('oboGo_Anthocyanin5OGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","an","anthocyanin","+","UDP-D-glucose","=","an","anthocyanin-5-O-glucoside","+","UDP","."),4182040). assertion_content_comment('oboGo_Anthocyanin6OMalonyltransferaseactivity',s("Catalysis","of","the","reaction",":","malonyl-CoA","+","an","anthocyanidin","3-O-beta-D-glucoside","=","CoA","+","an","anthocyanidin","3-O-","(","6-O-malonyl-beta-D-glucoside",")"),4342863). assertion_content_comment('oboGo_Anthracene910Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","anthracene","+","2","H2O","=","cis-9",",","10-dihydroanthracene-9",",","10-diol","."),4350466). assertion_content_comment('oboGo_Anthranilate12Dioxygenasedeaminatingdecarboxylatingactivity',s("Catalysis","of","the","reaction",":","anthranilate","+","NADPH","+","H","+","+","O2","=","catechol","+","CO2","+","NADP","+","+","NH3","."),4276888). assertion_content_comment('oboGo_Anthranilate3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","5",",","6",",","7",",","8-tetrahydrobiopterin","+","anthranilate","+","O","(","2",")","=","3-hydroxyanthranilate","+","7",",","8-dihydrobiopterin","+","H","(","2",")","O","."),4266351). assertion_content_comment('oboGo_Anthranilate3Monooxygenasedeaminatingactivity',s("Catalysis","of","the","reaction",":","anthranilate","+","2","H","(","+",")","+","NADPH","+","O","(","2",")","=","2",",","3-dihydroxybenzoate","+","NADP","(","+",")","+","NH","(","4",")","(","+",")"),4276431). assertion_content_comment('oboGo_AnthranilateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","anthranilate","+","CoA","=","AMP","+","diphosphate","+","anthranilyl-CoA","."),4273276). assertion_content_comment('oboGo_AnthranilateNBenzoyltransferaseactivity',s("Catalysis","of","the","reaction",":","anthranilate","+","benzoyl-CoA","=","N-benzoylanthranilate","+","CoA","."),4372871). assertion_content_comment('oboGo_AnthranilateNMalonyltransferaseactivity',s("Catalysis","of","the","reaction",":","anthranilate","+","malonyl-CoA","=","N-malonylanthranilate","+","CoA","."),4372905). assertion_content_comment('oboGo_AnthranilateNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","anthranilate","=","N-methylanthranilate","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4309155). assertion_content_comment('oboGo_AnthraniloylCoamonooxygenaseactivity',s("Catalysis","of","the","reaction",":","2-aminobenzoyl-CoA","+","2","NADPH","+","2","H","+","+","O2","=","2-amino-5-oxocyclohex-1-enecarboxyl-CoA","+","H2O","+","2","NADP","+"),4276350). assertion_content_comment('oboGo_AntiApoptosis',s("A","process","which","directly","inhibits","any","of","the","steps","required","for","cell","death","by","apoptosis","."),4042073). assertion_content_comment('oboGo_AntibodyDependentcellularcytotoxicity',s("Cytolysis","of","target","cells","by","natural","killer","cells",",","eosinophils",",","neutrophils",",","monocytes",",","or","macrophages","following","engagement","of","antibodies","bound","to","the","target","cells","by","Fc","receptors","on","the","effector","cells","."),3983117). assertion_content_comment('oboGo_AntigenProcessingAndPresentationInitiatedByTollLikereceptormediatedphagocytosisofantigen',s("Antigen","processing","and","presentation","which","is","initiated","by","phagocytosis","of","antigen","bound","directly","or","indirectly","to","a","cell","surface","toll-like","receptor","(","TLR",")"),4382540). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfEndogenousPeptideAntigenViaMHCClassIbViaERPathwayTAPDependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","endogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","Ib","protein","complex","following","intracellular","transport","via","a","TAP","(","transporter","associated","with","antigen","processing",")","pathway",".","The","peptide","is","typically","a","fragment","of","a","larger","endogenous","protein","which","has","been","degraded","within","the","cell","and","is","dependent","on","TAP","transport","from","the","cytosol","to","ER","for","association","with","the","MHC","class","Ib","molecule",".","Class","Ib","here","refers","to","non-classical","class","I","molecules",",","such","as","those","of","the","HLA-E","gene","family","."),4380702). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfEndogenousPeptideAntigenViaMHCClassIbViaERPathwayTAPIndependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","endogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","Ib","protein","complex","following","intracellular","transport","via","a","pathway","not","requiring","TAP","(","transporter","associated","with","antigen","processing",")","The","peptide","is","typically","a","fragment","of","a","larger","endogenous","protein","which","has","been","degraded","within","the","cell",".","Class","Ib","here","refers","to","non-classical","class","I","molecules",",","such","as","those","of","the","HLA-E","gene","family","."),4380588). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfEndogenousPeptideAntigenViaMHCClassIViaERPathwayTAPDependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","endogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","I","protein","complex","following","intracellular","transport","via","a","TAP-dependent","ER","pathway",".","The","peptide","is","typically","a","fragment","of","a","larger","endogenous","protein","which","has","been","degraded","within","the","cell","and","becomes","associated","with","the","MHC","class","I","molecule","in","the","ER","following","TAP-dependent","transport","from","the","cytosol",".","Class","I","here","refers","to","classical","class","I","molecules","."),4380714). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfEndogenousPeptideAntigenViaMHCClassIViaERPathwayTAPIndependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","endogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","I","protein","complex","following","intracellular","transport","via","a","TAP-independent","ER","pathway",".","The","peptide","is","typically","a","fragment","of","a","larger","endogenous","protein","which","has","been","degraded","within","the","cell","and","becomes","associated","with","the","MHC","class","I","molecule","in","the","ER","following","transport","from","the","cytosol","via","a","TAP-independent","pathway",".","Class","I","here","refers","to","classical","class","I","molecules","."),4380726). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfExogenousPeptideAntigenViaMHCClassITAPDependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","exogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","I","protein","complex","following","intracellular","transport","via","a","TAP","(","transporter","associated","with","antigen","processing",")","pathway",".","The","peptide","is","typically","a","fragment","of","a","larger","exogenous","protein","which","has","been","degraded","within","the","cell","and","is","dependent","on","TAP","transport","from","the","cytosol","to","ER","for","association","with","the","MHC","class","I","molecule",".","Class","I","here","refers","to","classical","class","I","molecules","."),4380972). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfExogenousPeptideAntigenViaMHCClassITAPIndependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","exogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","I","protein","complex","following","intracellular","transport","via","a","pathway","not","requiring","TAP","(","transporter","associated","with","antigen","processing",")","The","peptide","is","typically","a","fragment","of","a","larger","exogenous","protein","which","has","been","degraded","within","the","cell",".","Class","I","here","refers","to","classical","class","I","molecules","."),4380688). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfExogenousProteinAntigenViaMHCClassIbTAPDependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","exogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","Ib","protein","complex","following","intracellular","transport","via","a","TAP","(","transporter","associated","with","antigen","processing",")","pathway",".","The","peptide","is","typically","a","fragment","of","a","larger","exogenous","protein","which","has","been","degraded","within","the","cell","and","is","dependent","on","TAP","transport","from","the","cytosol","to","ER","for","association","with","the","MHC","class","Ib","molecule",".","Class","Ib","here","refers","to","non-classical","class","I","molecules",",","such","as","those","of","the","HLA-E","gene","family","."),4380654). assertion_content_comment('oboGo_AntigenProcessingAndPresentationOfExogenousProteinAntigenViaMHCClassIbTAPIndependent',s("The","process","in","which","an","antigen-presenting","cell","expresses","a","peptide","antigen","of","exogenous","origin","on","its","cell","surface","in","association","with","an","MHC","class","Ib","protein","complex","following","intracellular","transport","via","a","pathway","not","requiring","TAP","(","transporter","associated","with","antigen","processing",")","The","peptide","is","typically","a","fragment","of","a","larger","exogenous","protein","which","has","been","degraded","within","the","cell",".","Class","Ib","here","refers","to","non-classical","class","I","molecules",",","such","as","those","of","the","HLA-E","gene","family","."),4380666). assertion_content_comment('oboGo_AntigenReceptorMediatedsignalingpathway',s("A","series","of","molecular","signals","initiated","by","the","cross-linking","of","an","antigen","receptor","on","a","B","or","T","cell","."),4052281). assertion_content_comment('oboGo_AntigenSamplingByDendriticCellsInMucosalAssociatedlymphoidtissue',s("The","process","of","antigen","sampling","carried","out","by","dendritic","cells","in","the","mucosal-associated","lymphoid","tissue","."),3993494). assertion_content_comment('oboGo_AntigenSamplingByMCellsInMucosalAssociatedlymphoidtissue',s("The","process","of","antigen","samples","carried","out","by","M","cells","in","the","mucosal-associated","lymphoid","tissue","."),3993418). assertion_content_comment('oboGo_AntigenSamplingInMucosalAssociatedlymphoidtissue',s("The","process","of","apical-to-basolateral","delivery","of","soluble","and","particulate","antigens","to","underlying","mucosal-associated","lymphoid","tissue","."),3993413). assertion_content_comment('oboGo_AntigenTranscytosisByMCellsInMucosalAssociatedlymphoidtissue',s("The","process","of","antigen","transcytosis","carried","out","by","M","cells","in","the","mucosal-associated","lymphoid","tissue","(","MALT",")","Transcytosis","is","the","process","of","the","directed","movement","of","endocytosed","material","through","the","cell","and","its","exocytosis","from","the","plasma","membrane","at","the","opposite","side",".","M","cells","are","specialized","epithelia","cells","with","a","microfold","structure","that","are","adept","at","moving","antigens","from","the","gut","lumen","to","antigen","presenting","cells","in","the","MALT","."),3993438). assertion_content_comment('oboGo_AntimoniteTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","antimonite","(","in",")","=","ADP","+","phosphate","+","antimonite","(","out",")"),4316294). assertion_content_comment('oboGo_AntiSigmafactorantagonistactivity',s("The","function","of","binding","to","an","anti-sigma","factor","and","stopping",",","preventing","or","reducing","the","rate","of","its","activity","."),4327088). assertion_content_comment('oboGo_AP_1AdaptorComplexBinding',s("Interacting","selectively","and","non-covalently","with","the","AP-1","adaptor","complex",".","The","AP-1","adaptor","complex","is","a","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","beta1",",","gamma",",","mu1","and","sigma1","subunits","and","links","clathrin","to","the","membrane","surface","of","a","vesicle",".","In","at","least","humans",",","the","AP-1","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","genes","(","gamma1","and","gamma2",",","mu1A","and","mu1B",",","and","sigma1A",",","sigma1B","and","sigma1C",")"),4380204). assertion_content_comment('oboGo_AP_1AdaptorComplex',s("A","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","beta1",",","gamma",",","mu1","and","sigma1","subunits","and","links","clathrin","to","the","membrane","surface","of","a","vesicle",";","vesicles","with","AP-1-containing","coats","are","normally","found","primarily","in","the","trans-Golgi","network",".","In","at","least","humans",",","the","AP-1","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","genes","(","gamma1","and","gamma2",",","mu1A","and","mu1B",",","and","sigma1A",",","sigma1B","and","sigma1C",")"),4053158). assertion_content_comment('oboGo_AP_2AdaptorComplexBinding',s("Interacting","selectively","and","non-covalently","with","the","AP-2","adaptor","complex",".","The","AP-2","adaptor","complex","is","a","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","alpha",",","beta2",",","mu2","and","sigma2","subunits","and","links","clathrin","to","the","membrane","surface","of","a","vesicle",".","In","at","least","humans",",","the","AP-2","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","alpha","genes","(","alphaA","and","alphaC",")"),4379952). assertion_content_comment('oboGo_AP_2AdaptorComplex',s("A","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","alpha",",","beta2",",","mu2","and","sigma2","subunits",",","and","links","clathrin","to","the","membrane","surface","of","a","vesicle",";","vesicles","with","AP-2-containing","coats","are","normally","found","primarily","near","the","plasma","membrane",",","on","endocytic","vesicles",".","In","at","least","humans",",","the","AP-2","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","alpha","genes","(","alphaA","and","alphaC",")"),4053173). assertion_content_comment('oboGo_AP_3AdaptorComplexBinding',s("Interacting","selectively","and","non-covalently","with","the","AP-3","adaptor","complex",".","The","AP-3","adaptor","complex","is","a","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","beta3",",","delta",",","mu3","and","sigma3","subunits","and","is","found","associated","with","endosomal","membranes",".","In","at","least","humans",",","the","AP-3","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","genes","(","beta3A","and","beta3B",",","mu3A","and","mu3B",",","and","sigma3A","and","sigma3B",")"),4380213). assertion_content_comment('oboGo_AP_3AdaptorComplex',s("A","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that","consists","of","beta3",",","delta",",","mu3","and","sigma3","subunits","and","is","found","associated","with","endosomal","membranes",".","AP-3","does","not","appear","to","associate","with","clathrin","in","all","organisms",".","In","at","least","humans",",","the","AP-3","complex","can","be","heterogeneric","due","to","the","existence","of","multiple","subunit","isoforms","encoded","by","different","genes","(","beta3A","and","beta3B",",","mu3A","and","mu3B",",","and","sigma3A","and","sigma3B",")"),4311023). assertion_content_comment('oboGo_AP_4AdaptorComplex',s("An","AP-type","membrane","coat","adaptor","complex","that","consists","of","beta4",",","epsilon",",","mu4","and","sigma4","subunits","and","is","found","associated","with","membranes","in","the","trans-Golgi","network",";","it","is","not","clear","whether","AP-4","forms","clathrin","coats","in","vivo","."),4311014). assertion_content_comment('oboGo_APC_Axin_1_Beta_CateninComplex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","Axin-1",",","and","beta-catenin","."),4349438). assertion_content_comment('oboGo_APCIqgap1Cdc42complex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","the","small","GTPase","Cdc42",",","and","the","Rac1","and","Cdc42","effector","IQGAP1",";","may","play","a","role","in","cytoskeleton","organization","and","cell","migration","."),4073417). assertion_content_comment('oboGo_APC_IQGAP1_CLIP_170Complex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","the","small","GTPase","Cdc42",",","and","CLIP-170",";","may","play","a","role","in","cytoskeleton","organization","and","cell","migration","."),4073452). assertion_content_comment('oboGo_APCIqgap1Rac1complex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","the","small","GTPase","Rac1",",","and","the","Rac1","and","Cdc42","effector","IQGAP1",";","may","play","a","role","in","cytoskeleton","organization","and","cell","migration","."),4073429). assertion_content_comment('oboGo_APCIqgapcomplex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")","and","the","Rac1","and","Cdc42","effector","IQGAP1",";","may","play","a","role","in","cytoskeleton","organization","and","cell","migration","."),4073405). assertion_content_comment('oboGo_APCTubulinIqgap1complex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","alpha-tubulin",",","gamma-tubulin",",","and","the","Rac1","and","Cdc42","effector","IQGAP1",";","may","play","a","role","in","cytoskeleton","organization","."),4349426). assertion_content_comment('oboGo_ApelinLikereceptor',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4360503). assertion_content_comment('oboGo_APG8Specificproteaseactivity',s("Catalysis","of","the","hydrolysis","of","APG8",",","a","small","ubiquitin-related","modifier","."),4245378). assertion_content_comment('oboGo_Aphidicolan_16Beta_OlSynthaseActivity',s("Catalysis","of","the","formation","of","aphidicolan-16","beta-ol","from","geranylgeranyl","diphosphate","."),4358776). assertion_content_comment('oboGo_ApicalHemiAdherensjunction',s("A","cell-substrate","adherens","junction","found","in","the","apical","region","of","a","cell",",","such","as","those","found","in","cuticle-secreting","epithelia",",","which","connect","the","apical","membrane","to","the","cuticle","."),4220673). assertion_content_comment('oboGo_Apigenin4OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","5",",","7",",","4","'","-trihydroxyflavone","=","S-adenosyl-L-homocysteine","+","4","'","-methoxy-5",",","7-dihydroxyflavone","."),4308592). assertion_content_comment('oboGo_Apiose1Reductaseactivity',s("Catalysis","of","the","reaction",":","D-apiitol","+","NAD","(","+",")","=","D-apiose","+","H","(","+",")","+","NADH","."),4372893). assertion_content_comment('oboGo_Apo_Beta_Carotenoid_1413_DioxygenaseActivity',s("Catalysis","of","the","reaction",":","8","'","-apo-beta-carotenol","+","O","(","2",")","=","(","E",",","E",")","-7-hydroxy-6-methylhepta-3",",","5-dienal","+","14","'","-apo-beta-carotenal","."),4268049). assertion_content_comment('oboGo_ApolipoproteinAIbinding',s("Interacting","selectively","and","non-covalently","with","apolipoprotein","A-I","."),4359349). assertion_content_comment('oboGo_ApolipoproteinAIreceptoractivity',s("Combining","with","apolipoprotein","A-I","to","initiate","a","change","in","cell","activity","."),4359351). assertion_content_comment('oboGo_ApolipoproteinAIreceptorbinding',s("Interacting","selectively","and","non-covalently","with","an","apolipoprotein","A-I","receptor","."),4359411). assertion_content_comment('oboGo_AppositionOfDorsalAndVentralImaginalDiscDerivedwingsurfaces',s("The","coming","together","of","the","dorsal","and","ventral","surfaces","of","the","imaginal","disc-derived","wing","during","the","conversion","of","a","folded","single","layered","wing","disc","to","a","flat","bilayered","wing","."),4017970). assertion_content_comment('oboGo_APTypemembranecoatadaptorcomplex',s("Any","of","several","heterotetrameric","complexes","that","link","clathrin","(","or","another","coat-forming","molecule",",","as","hypothesized","for","AP-3","and","AP-4",")","to","a","membrane","surface",";","they","are","found","on","coated","pits","and","coated","vesicles",",","and","mediate","sorting","of","cargo","proteins","into","vesicles",".","Each","AP","complex","contains","two","large","(","a","beta","and","one","of","either","an","alpha",",","gamma",",","delta",",","or","epsilon",")","subunits","(","110-130","kDa",")",",","a","medium","(","mu",")","subunit","(","approximately","50","kDa",")",",","and","a","small","(","sigma",")","subunit","(","15-20","kDa",")"),4053045). assertion_content_comment('oboGo_ArabinanEndo_15_Alpha_L_ArabinosidaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","5-alpha-arabinofuranosidic","linkages","in","1",",","5-arabinans","."),4359110). assertion_content_comment('oboGo_ArabinogalactanEndo_14_Beta_GalactosidaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-galactosidic","linkages","in","arabinogalactans","."),4319979). assertion_content_comment('oboGo_Arabinose_5_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-arabinose","5-phosphate","=","D-ribulose","5-phosphate","+","2","H","(","+",")"),4237452). assertion_content_comment('oboGo_Arachidonate12Lipoxygenaseactivity',s("Catalysis","of","the","reaction",":","arachidonate","+","O","(","2",")","=","(","5Z",",","8Z",",","10E",",","12S",",","14Z",")","-12-hydroperoxyicosa-5",",","8",",","10",",","14-tetraenoate","."),4213717). assertion_content_comment('oboGo_Arachidonate15Lipoxygenaseactivity',s("Catalysis","of","the","reaction",":","arachidonate","+","O2","=","(","5Z",",","8Z",",","11Z",",","13E",")","-","(","15S",")","-15-hydroperoxyicosa-5",",","8",",","11",",","13-tetraenoate","."),4266131). assertion_content_comment('oboGo_Arachidonate5Lipoxygenaseactivity',s("Catalysis","of","the","reaction",":","arachidonate","+","O2","=","(","6E",",","8Z",",","11Z",",","14Z",")","-","(","5S",")","-5-hydroperoxycosa-6",",","8",",","11",",","14-tetraenoate","."),4213668). assertion_content_comment('oboGo_Arachidonate8Lipoxygenaseactivity',s("Catalysis","of","the","reaction",":","arachidonate","+","O","(","2",")","=","(","5Z",",","8R",",","9E",",","11Z",",","14Z",")","-8-hydroperoxyicosa-5",",","9",",","11",",","14-tetraenoate","."),4372950). assertion_content_comment('oboGo_ArachidonateCoaligaseactivity',s("Catalysis","of","the","reaction",":","arachidonate","+","ATP","+","CoA","=","AMP","+","arachidonoyl-CoA","+","diphosphate","+","H","(","+",")"),4372915). assertion_content_comment('oboGo_ArachidonicAcid1112Epoxygenaseactivity',s("Catalysis","of","an","NADPH-","and","oxygen-dependent","reaction","that","converts","arachidonic","acid","to","cis-11",",","12-epoxyeicosatrienoic","acid","."),4255783). assertion_content_comment('oboGo_ArachidonicAcid1415Epoxygenaseactivity',s("Catalysis","of","an","NADPH-","and","oxygen-dependent","reaction","that","converts","arachidonic","acid","to","cis-14",",","15-epoxyeicosatrienoic","acid","."),4255793). assertion_content_comment('oboGo_AralkylamineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","an","aralkylamine","=","CoA","+","an","N-acetylaralkylamine","."),4213734). assertion_content_comment('oboGo_ARFGuanylNucleotideexchangefactoractivity',s("Stimulates","the","exchange","of","guanyl","nucleotides","associated","with","the","GTPase","ARF",".","Under","normal","cellular","physiological","conditions",",","the","concentration","of","GTP","is","higher","than","that","of","GDP",",","favoring","the","replacement","of","GDP","by","GTP","in","association","with","the","GTPase","."),4215531). assertion_content_comment('oboGo_Arginine2Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","L-arginine","+","O","(","2",")","=","4-guanidinobutanamide","+","CO","(","2",")","+","H","(","2",")","O","."),4372937). assertion_content_comment('oboGo_ArginineImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","arginine","(","out",")","=","ADP","+","phosphate","+","arginine","(","in",")"),4293673). assertion_content_comment('oboGo_ArginineNMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","from","S-adenosyl-L-methionine","to","an","amino","group","of","an","arginine","residue","."),4177080). assertion_content_comment('oboGo_ArginineNSuccinyltransferaseactivity',s("Catalysis","of","the","reaction",":","succinyl-CoA","+","L-arginine","=","CoA","+","N2-succinyl-L-arginine","."),4248967). assertion_content_comment('oboGo_ArginineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-arginine","+","tRNA","(","Arg",")","=","AMP","+","diphosphate","+","L-arginyl-tRNA","(","Arg",")"),4199966). assertion_content_comment('oboGo_ArginylTrnaaminoacylation',s("The","process","of","coupling","arginine","to","arginyl-tRNA",",","catalyzed","by","arginyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179839). assertion_content_comment('oboGo_ArogenateDehydrogenaseNADPActivity_5',s("Catalysis","of","the","reaction",":","L-arogenate","+","NADP","+","=","L-tyrosine","+","NADPH","+","CO2","."),4342612). assertion_content_comment('oboGo_AromaticAminoAcid_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","an","aromatic","amino","acid","+","2-oxoglutarate","=","an","aromatic","oxo","acid","+","L-glutamate","."),4248939). assertion_content_comment('oboGo_AromaticAminoAcidGlyoxylatetransaminaseactivity',s("Catalysis","of","the","reaction",":","glyoxylate","+","an","aromatic","amino","acid","=","L-glycine","+","an","aromatic","oxo","acid","."),4368869). assertion_content_comment('oboGo_AromaticHydroxylamineoAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-hydroxy-4-aminobiphenyl","+","N-hydroxy-4-acetylaminonbiphenyl","=","N-acetoxy-4-aminobiphenyl","+","N-hydroxy-4-aminobiphenyl","."),4366270). assertion_content_comment('oboGo_AromaticLAminoAciddecarboxylaseactivity',s("Catalysis","of","the","reaction",":","L-tryptophan","=","tryptamine","+","CO2","."),4213751). assertion_content_comment('oboGo_Arp23ComplexMediatedactinnucleation',s("The","actin","nucleation","process","in","which","actin","monomers","combine","to","form","a","new","branch","on","the","side","of","an","existing","actin","filament",";","mediated","by","the","Arp2/3","protein","complex","and","its","interaction","with","other","proteins","."),4075087). assertion_content_comment('oboGo_ArseniteTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","arsenite","(","in",")","=","ADP","+","phosphate","+","arsenite","(","out",")"),4292050). assertion_content_comment('oboGo_ArylAcylamidaseactivity',s("Catalysis","of","the","reaction",":","anilide","+","H","(","2",")","O","=","a","carboxylate","+","aniline","+","H","(","+",")"),4372761). assertion_content_comment('oboGo_ArylAlcoholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","an","aromatic","alcohol","+","NAD","+","=","an","aromatic","aldehyde","+","NADH","+","H","+"),4281686). assertion_content_comment('oboGo_ArylAlcoholdehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","an","aromatic","alcohol","+","NADP","+","=","an","aromatic","aldehyde","+","NADPH","."),4372748). assertion_content_comment('oboGo_ArylAlcoholoxidaseactivity',s("Catalysis","of","the","reaction",":","an","aromatic","primary","alcohol","+","O2","=","an","aromatic","aldehyde","+","H2O2","."),4372735). assertion_content_comment('oboGo_ArylAldehydedehydrogenasenadactivity',s("Catalysis","of","the","reaction",":","an","aromatic","aldehyde","+","NAD","+","+","H2O","=","an","aromatic","acid","+","NADH","+","H","+"),4237040). assertion_content_comment('oboGo_ArylAldehydedehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","an","aromatic","aldehyde","+","NADP","+","+","AMP","+","diphosphate","+","H2O","=","an","aromatic","acid","+","NADPH","+","ATP","."),4372724). assertion_content_comment('oboGo_ArylAldehydeoxidaseactivity',s("Catalysis","of","the","reaction",":","an","aromatic","aldehyde","+","O2","+","H2O","=","an","aromatic","acid","+","hydrogen","peroxide","."),4265799). assertion_content_comment('oboGo_ArylamineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","an","arylamine","=","CoA","+","an","N-acetylarylamine","."),4212860). assertion_content_comment('oboGo_ArylCoasynthetaseadpFormingactivity',s("Catalysis","of","the","reaction",":","ATP","+","phenylacetate","+","CoA","=","ADP","+","orthophosphate","+","phenylacetyl-CoA","."),4326095). assertion_content_comment('oboGo_Ascorbate23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","L-ascorbate","+","H","(","2",")","O","+","O","(","2",")","=","L-threonate","+","2","H","(","+",")","+","oxalate","."),4372775). assertion_content_comment('oboGo_AscosporeTypeprosporeformation',s("During","ascospore","formation",",","the","process","in","which","each","haploid","nucleus","becomes","encapsulated","by","a","double","membrane","."),4054895). assertion_content_comment('oboGo_AscosporeTypeprosporemembraneassembly',s("The","process","in","which","the","nascent","membrane","forms","at","the","meiotic","outer","plaque","and","grows","until","closure","occurs","and","forespores",",","or","prospores",",","are","formed","."),4054920). assertion_content_comment('oboGo_AscosporeTypeprospore',s("An","immature","spore","undergoing","development",".","The","spore","usually","consists","of","nucleic","acid",",","prospore","membrane","(","s",")","that","encase","the","nucleic","acid",",","and","ultimately","a","cell","wall","that","covers","the","membrane","(","s",")","This","type","of","spore","is","observed","in","ascopore-forming","fungi","."),4006963). assertion_content_comment('oboGo_AscosporeTypeprosporeSpecificspindlepolebodyremodeling',s("A","spindle","pole","body","(","SPB",")","organization","process","that","takes","place","during","the","second","meiotic","division","during","ascospore","formation","and","results","in","the","structural","reorganization","of","the","SPB",";","includes","the","recruitment","of","sporulation-specific","proteins","to","the","outer","plaque","to","form","the","meiotic","outer","plaque","(","MOP",")"),4059342). assertion_content_comment('oboGo_AscosporeWall13BetaDGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1",",","3-beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4111560). assertion_content_comment('oboGo_AscosporeWall13BetaDGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-1",",","3","glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4111464). assertion_content_comment('oboGo_AscosporeWallBetaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4111494). assertion_content_comment('oboGo_AscosporeWallBetaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4074643). assertion_content_comment('oboGo_AsioloorosomucoidBeta_13_GlucuronosyltransferaseActivity',s("Catalysis","of","the","transfer",",","in","a","beta","1",",","3","linkage",",","of","D-glucuronic","acid","(","GlcUA",")","from","UDP-GlcUA","to","asioloorosomucoid","."),4361728). assertion_content_comment('oboGo_AsparagineCatabolicProcessVia2Oxosuccinamate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate",",","via","the","intermediate","2-oxosuccinamate","."),4338625). assertion_content_comment('oboGo_AsparagineCatabolicProcessViaLAspartate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate",",","via","the","intermediate","L-aspartate","."),4338645). assertion_content_comment('oboGo_AsparagineOxoAcidtransaminaseactivity',s("Catalysis","of","the","reaction",":","a","2-oxo","acid","+","L-asparagine","=","an","amino","acid","+","2-oxosuccinamate","."),4367695). assertion_content_comment('oboGo_AsparagineSynthaseGlutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-aspartate","+","L-glutamine","=","AMP","+","diphosphate","+","L-asparagine","+","L-glutamate","."),4212709). assertion_content_comment('oboGo_AsparagineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","L-asparagine","+","ATP","+","tRNA","(","Asn",")","=","AMP","+","Asn-tRNA","(","Asn",")","+","diphosphate","+","2","H","(","+",")"),4200000). assertion_content_comment('oboGo_AsparaginylTrnaaminoacylation',s("The","process","of","coupling","asparagine","to","asparaginyl-tRNA",",","catalyzed","by","asparaginyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179859). assertion_content_comment('oboGo_AsparaginylTrnaasnbiosynthesisviatransamidation',s("A","tRNA","aminoacylation","process","in","which","asparaginyl-tRNAAsn","is","formed","by","a","tRNA-dependent","two-step","pathway",".","In","the","first","step","a","non-discriminating","aspartyl-tRNA","synthetase","generates","the","misacylated","L-aspartyl-tRNAAsn","species",",","and","in","the","second","step","it","is","amidated","to","the","correctly","charged","L-asparaginyl-tRNAAsn","by","the","heterotrimeric","aspartyl-tRNAAsn","amidotransferase","."),4177315). assertion_content_comment('oboGo_AsparaginylTrnasynthaseglutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","L-glutamine","+","aspartyl-tRNA","(","Asn",")","+","ATP","=","L-glutamate","+","asparaginyl-tRNA","(","Asn",")","+","phosphate","+","ADP","."),4268383). assertion_content_comment('oboGo_Aspartate1Decarboxylaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","=","beta-alanine","+","CO2","."),4212727). assertion_content_comment('oboGo_Aspartate_2_Keto_4_MethylthiobutyrateTransaminaseActivity',s("Catalysis","of","the","reaction",":","2-keto-4-methylthiobutyrate","+","aspartate","=","methionine","+","oxaloacetate","."),4358937). assertion_content_comment('oboGo_Aspartate4Decarboxylaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","=","L-alanine","+","CO2","."),4372839). assertion_content_comment('oboGo_AspartateAmmonialigaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-aspartate","+","NH3","=","AMP","+","diphosphate","+","L-asparagine","."),4212652). assertion_content_comment('oboGo_AspartateAmmonialigaseadpFormingactivity',s("Catalysis","of","the","reaction",":","L-aspartate","+","ATP","+","NH","(","4",")","(","+",")","=","L-asparagine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4369615). assertion_content_comment('oboGo_AspartateAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","=","fumarate","+","NH3","."),4248997). assertion_content_comment('oboGo_AspartateNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","+","acetyl-CoA","=","N-acetyl-L-aspartate","+","CoA","+","H","(","+",")"),4258386). assertion_content_comment('oboGo_AspartatePhenylpyruvatetransaminaseactivity',s("Catalysis","of","the","reaction",":","keto-phenylpyruvate","+","L-aspartate","=","L-phenylalanine","+","oxaloacetate","."),4369101). assertion_content_comment('oboGo_AspartatePrephenateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-arogenate","+","oxaloacetate","=","prephenate","+","L-aspartate","."),4343801). assertion_content_comment('oboGo_AspartateSemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","4-semialdehyde","+","NADP","(","+",")","+","phosphate","=","4-phospho-L-aspartate","+","H","(","+",")","+","NADPH","."),4212635). assertion_content_comment('oboGo_AspartateTrnaasnligaseactivity',s("Catalysis","of","the","reaction",":","tRNA","(","Asx",")","+","L-aspartate","+","ATP","=","aspartyl-tRNA","(","Asx",")","+","diphosphate","+","AMP","."),4268335). assertion_content_comment('oboGo_AspartateTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-aspartate","+","tRNA","(","Asp",")","=","AMP","+","diphosphate","+","L-aspartyl-tRNA","(","Asp",")"),4199983). assertion_content_comment('oboGo_AsparticTypeendopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","internal",",","alpha-peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","a","water","molecule","bound","by","the","side","chains","of","aspartic","residues","at","the","active","center","acts","as","a","nucleophile","."),4210365). assertion_content_comment('oboGo_AsparticTypeendopeptidaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","aspartic-type","endopeptidases",",","enzymes","that","catalyze","the","hydrolysis","of","nonterminal","peptide","bonds","in","a","polypeptide","chain",";","the","optimum","reaction","pH","is","below","5","due","to","an","aspartic","residue","involved","in","the","catalytic","process","."),4233280). assertion_content_comment('oboGo_AsparticTypepeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","a","water","molecule","bound","by","the","side","chains","of","aspartic","residues","at","the","active","center","acts","as","a","nucleophile","."),4180775). assertion_content_comment('oboGo_AsparticTypesignalpeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","cleavage","of","a","signal","peptide","from","a","protein","precursor","by","an","aspartic","endopeptidase","mechanism","."),4257030). assertion_content_comment('oboGo_AspartylTrnaaminoacylation',s("The","process","of","coupling","aspartate","to","aspartyl-tRNA",",","catalyzed","by","aspartyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179879). assertion_content_comment('oboGo_AssemblyOfSpliceosomalTriSnrnp',s("The","formation","of","a","tri-snRNP","complex","containing","U4","and","U6","(","or","U4atac","and","U6atac",")","snRNAs","and","U5","snRNAs","and","associated","proteins",".","This","includes","reannealing","of","U4","and","U6","(","or","U4atac","and","U6atac",")","snRNAs","released","from","previous","rounds","of","splicing","to","reform","the","U4/U6","snRNP","(","or","U4atac/U6atac","snRNP",")","as","well","as","the","subsequent","association","of","the","U5","snRNP","with","the","U4/U6","snRNP","(","or","U4atac/U6atac","snRNP",")","to","form","a","tri-snRNP","that","is","ready","to","reassemble","into","another","spliceosome","complex","."),3973604). assertion_content_comment('oboGo_Atg12Atg5Atg16complex',s("A","protein","complex","required","for","the","expansion","of","the","autophagosomal","membrane",".","In","budding","yeast",",","this","complex","consists","of","Atg12p",",","Atg5p","and","Atg16p","."),4360328). assertion_content_comment('oboGo_ATP_2Methylpropanoatephosphotransferaseactivity',s("Catalysis","of","the","reaction",":","2-methylpropanoate","+","ATP","=","2-methylpropanoyl","phosphate","+","ADP","+","H","(","+",")"),4373132). assertion_content_comment('oboGo_ATPActivatedinwardrectifierpotassiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","potassium","ion","by","an","inwardly-rectifying","voltage-gated","channel",",","where","the","inward","rectification","is","due","to","a","voltage-dependent","block","of","the","channel","pore","by","ATP",".","An","inwardly","rectifying","current-voltage","relation","is","one","where","at","any","given","driving","force","the","inward","flow","of","K","+","ions","exceeds","the","outward","flow","for","the","opposite","driving","force","."),4295189). assertion_content_comment('oboGo_ATPActivatednucleotidereceptoractivity',s("Combining","with","adenosine","and","transmitting","the","signal","to","a","heterotrimeric","G-protein","complex","to","initiate","a","change","in","cell","activity",",","activated","by","ATP","."),4300961). assertion_content_comment('oboGo_ATPBindingandphosphorylationDependentchloridechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","ATP","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4217653). assertion_content_comment('oboGo_ATPBindingcassetteabctransporteractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4212900). assertion_content_comment('oboGo_ATPBindingcassetteabctransportercomplexintegratedsubstratebinding',s("A","complex","for","the","transport","of","metabolites","out","of","the","cell",",","consisting","of","4","domains",":","two","ATP-binding","domains","and","two","membrane","spanning","domains",".","In","some","cases",",","all","4","domains","are","contained","on","1","polypeptide",",","while","in","others","one","ATP-binding","domain","and","one","membrane","spanning","domain","are","together","on","one","polypeptide","in","what","is","called","a","\"","half","transporter","\"","Two","\"","half-transporters","\"","come","together","to","form","a","functional","transporter",".","Transport","of","the","substrate","across","the","membrane","is","driven","by","the","hydrolysis","of","ATP","."),4221911). assertion_content_comment('oboGo_ATPBindingcassetteabctransportercomplex',s("A","complex","for","the","transport","of","metabolites","into","and","out","of","the","cell",",","typically","comprised","of","four","domains",";","two","membrane-associated","domains","and","two","ATP-binding","domains","at","the","intracellular","face","of","the","membrane",",","that","form","a","central","pore","through","the","plasma","membrane",".","Each","of","the","four","core","domains","may","be","encoded","as","a","separate","polypeptide","or","the","domains","can","be","fused","in","any","one","of","a","number","of","ways","into","multidomain","polypeptides",".","In","Bacteria","and","Archaebacteria",",","ABC","transporters","also","include","substrate","binding","proteins","to","bind","substrate","external","to","the","cytoplasm","and","deliver","it","to","the","transporter","."),4212892). assertion_content_comment('oboGo_ATPBindingcassetteabctransportercomplexsubstrateBindingsubunitContaining',s("A","complex","for","the","transport","of","metabolites","into","the","cell",",","consisting","of","5","subunits",":","two","ATP-binding","subunits",",","two","membrane","spanning","subunits",",","and","one","substrate-binding","subunit",".","In","organisms","with","two","membranes",",","the","substrate-binding","protein","moves","freely","in","the","periplasmic","space","and","joins","the","other","subunits","only","when","bound","with","substrate",".","In","organisms","with","only","one","membrane","the","substrate-binding","protein","is","tethered","to","the","cytoplasmic","membrane","and","associated","with","the","other","subunits",".","Transport","of","the","substrate","across","the","membrane","is","driven","by","the","hydrolysis","of","ATP","."),4221902). assertion_content_comment('oboGo_ATPBindingcassetteabctransportercomplextransmembranesubstrateBindingsubunitContaining',s("A","complex","for","the","transport","of","metabolites","into","the","cell",",","consisting","of","4","subunits",":","a","transmembrane","substrate-binding","protein","(","known","as","the","S","component",")",",","and","an","energy-coupling","module","that","comprises","two","ATP-binding","proteins","(","known","as","the","A","and","A","'","components",")","and","a","transmembrane","protein","(","known","as","the","T","component",")","Transport","of","the","substrate","across","the","membrane","is","driven","by","the","hydrolysis","of","ATP","."),4381298). assertion_content_comment('oboGo_ATP_Dependent3_5DNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","drives","the","unwinding","of","the","DNA","helix","in","the","direction","3","'","to","5","'"),4317513). assertion_content_comment('oboGo_ATP_Dependent3_5DNARNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","a","DNA/RNA","duplex","in","the","direction","3","'","to","5","'"),4341221). assertion_content_comment('oboGo_ATP_Dependent3_5RNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","an","RNA","helix","in","the","direction","3","'","to","5","'"),4357681). assertion_content_comment('oboGo_ATP_Dependent5_3DNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","drives","the","unwinding","of","the","DNA","helix","in","the","direction","5","'","to","3","'"),4317563). assertion_content_comment('oboGo_ATP_Dependent5_3DNARNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","a","DNA/RNA","duplex","in","the","direction","5","'","to","3","'"),4341232). assertion_content_comment('oboGo_ATP_Dependent5_3RNAHelicaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","an","RNA","helix","in","the","direction","5","'","to","3","'"),4331762). assertion_content_comment('oboGo_ATPDependentchromatinremodeling',s("Dynamic","structural","changes","to","eukaryotic","chromatin","that","require","energy","from","the","hydrolysis","of","ATP",",","ranging","from","local","changes","necessary","for","transcriptional","regulation","to","global","changes","necessary","for","chromosome","segregation",",","mediated","by","ATP-dependent","chromatin-remodelling","factors","."),4072698). assertion_content_comment('oboGo_ATPDependentdnahelicaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","the","DNA","helix","."),4212985). assertion_content_comment('oboGo_ATPDependentdnarnahelicaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","a","DNA/RNA","duplex","."),4341211). assertion_content_comment('oboGo_ATPDependenthelicaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",",","to","drive","the","unwinding","of","a","DNA","or","RNA","helix","."),4212982). assertion_content_comment('oboGo_ATPDependentnadphHydratedehydrataseactivity',s("Catalysis","of","the","reaction",":","(","6S",")","-6beta-hydroxy-1",",","4",",","5",",","6-tetrahydronicotinamide","adenine","dinucleotide","+","ATP","=","ADP","+","3","H","(","+",")","+","NADH","+","phosphate","."),4369351). assertion_content_comment('oboGo_ATPDependentpeptidaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",",","to","drive","the","hydrolysis","of","peptide","bonds","."),4210849). assertion_content_comment('oboGo_ATPDependentpolydeoxyribonucleotide5HydroxylKinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","5","'","-dephospho-DNA","=","ADP","+","5","'","-phospho-DNA","."),4351404). assertion_content_comment('oboGo_ATPDependentpolynucleotidekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","5","'","-dephosphopolynucleotide","=","ADP","+","5","'","-phosphopolynucleotide",".","The","polynucleotide","may","be","DNA","or","RNA","."),4281073). assertion_content_comment('oboGo_ATPDependentpolyribonucleotide5HydroxylKinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","5","'","-dephospho-RNA","=","ADP","+","5","'","-phospho-RNA","."),4281086). assertion_content_comment('oboGo_ATPDependentproteinbinding',s("Interacting","selectively","and","non-covalently","with","any","protein","or","protein","complex","(","a","complex","of","two","or","more","proteins","that","may","include","other","nonprotein","molecules",")","using","energy","from","the","hydrolysis","of","ATP","."),4318039). assertion_content_comment('oboGo_ATPDependentproteolysis',s("OBSOLETE",".","The","hydrolysis","of","a","peptide","bond","or","bonds","within","a","protein","using","energy","from","the","hydrolysis","of","ATP","."),4231340). assertion_content_comment('oboGo_ATPDependentrnahelicaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","drives","the","unwinding","of","an","RNA","helix","."),4213009). assertion_content_comment('oboGo_ATPGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","ATP","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4198578). assertion_content_comment('oboGo_ATPSensitivepotassiumchannelcomplex',s("A","protein","complex","that","comprises","four","pore-forming","(","Kir6.x",")","and","four","regulatory","sulphonylurea","receptor","(","SURx",")","subunits","and","forms","a","transmembrane","channel","through","which","ions","may","pass",".","The","opening","and","closing","of","the","channel","is","regulated","by","ATP",":","binding","of","ATP","to","the","Kir6.2","subunit","inhibits","channel","activity",",","whereas","binding","of","Mg2","+","-complexed","ATP","or","ADP","to","the","SUR1","subunit","stimulates","channel","activity","."),4020799). assertion_content_comment('oboGo_ATRAtripcomplex',s("A","protein","complex","that","contains","the","protein","kinase","ATR","and","ATR-interacting","protein","(","ATRIP",")","and","binds","single-stranded","DNA",";","ssDNA","binding","affinity","is","increased","in","the","presence","of","replication","protein","A","."),4172940). assertion_content_comment('oboGo_AtrazineNDealkylaseactivity',s("Catalysis","of","the","reaction",":","atrazine","+","O2","+","2","H","+","=","deethylatrazine","+","acetaldehyde","+","H2O","."),4276706). assertion_content_comment('oboGo_ATypetransientoutwardpotassiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","potassium","ion","by","an","outwardly-rectifying","voltage-gated","channel","that","produces","a","transient","outward","current","upon","a","step","change","in","membrane","potential","."),4217909). assertion_content_comment('oboGo_AUACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AUA","codon","."),4339834). assertion_content_comment('oboGo_AUCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AUC","codon","."),4339846). assertion_content_comment('oboGo_AUGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AUG","codon","."),4340017). assertion_content_comment('oboGo_AURichelementbinding',s("Interacting","selectively","and","non-covalently","with","AU-rich","elements","within","the","3","'","untranslated","region","of","mRNAs","."),4267763). assertion_content_comment('oboGo_Autoinducer_2KinaseActivity',s("Catalysis","of","the","reaction",":","4",",","5-dihydroxy-pentane-2",",","3-dione","+","ATP","=","5-phospho-4-hydroxy-pentane-2",",","3-dione","(","P-DPD",")","+","ADP","."),4172248). assertion_content_comment('oboGo_AUUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","an","AUU","codon","."),4339858). assertion_content_comment('oboGo_AxinApcBetaCateninGsk3bcomplex',s("A","protein","complex","that","contains","the","tumor","suppressor","protein","adenomatous","polyposis","coli","(","APC",")",",","Axin-1",",","beta-catenin",",","and","glycogen","synthase","kinase","3","beta",".","Formation","of","this","complex","leads","to","phosphorylation","of","beta-catenin","and","down-regulation","of","beta-catenin","activity","."),4349473). assertion_content_comment('oboGo_AxonemalHeterotrimericKinesinIicomplex',s("A","kinesin","complex","found","in","eukaryotic","axonemes","that","contains","two","distinct","plus","end-directed","kinesin","motor","proteins","and","at","least","one","accessory","subunit",",","and","that","functions","in","the","anterograde","transport","of","molecules","(","cargo",")","from","the","basal","body","to","the","distal","tip","of","the","axoneme","."),4307198). assertion_content_comment('oboGo_Azetidine_2_CarboxylicAcidAcetyltransferaseActivity',s("Catalysis","of","the","reaction",":","L-azetidine-2-carboxylic","acid","+","acetyl-CoA","=","CoA-SH","+","N-acetyl","azetidine-2-carboxylic","acid","."),4362119). assertion_content_comment('oboGo_B_1aBCellDifferentiation',s("The","process","in","which","B","cells","acquire","the","specialized","features","of","B-1a","B","cells",".","B-1a","B","cells","are","B-1","cells","that","express","CD5","and","arise","from","fetal","liver","precursors","."),4379703). assertion_content_comment('oboGo_B_1bBCellDifferentiation',s("The","process","in","which","B","cells","acquire","the","specialized","features","of","B-1b","B","cells",".","B-1b","B","cells","are","B-1","cells","that","do","not","express","CD5","."),4379680). assertion_content_comment('oboGo_B_1BCellDifferentiation',s("The","process","in","which","a","hemopoietic","stem","cell","acquires","the","specialized","features","of","a","B-1","B","cell",".","B-1","B","cells","are","a","distinct","subset","of","B","cells","characterized","as","being","CD5","positive",",","found","predominantly","in","the","peritoneum",",","pleural","cavities",",","and","spleen",",","and","enriched","for","self-reactivity","."),3989014). assertion_content_comment('oboGo_B_1BCellHomeostasis',s("The","process","of","regulating","the","proliferation","and","elimination","of","B","cells","of","the","B-1","subset","such","that","the","total","number","of","B-1","B","cells","within","a","whole","or","part","of","an","organism","is","stable","over","time","in","the","absence","of","an","outside","stimulus",".","B-1","B","cells","are","a","distinct","subset","of","B","cells","characterized","as","being","CD5","positive",",","found","predominantly","in","the","peritoneum",",","pleural","cavities",",","and","spleen",",","and","enriched","for","self-reactivity","."),4384119). assertion_content_comment('oboGo_B_1BCellLineageCommitment',s("The","process","in","which","an","immature","B","cell","becomes","committed","to","become","a","B-1","B","cell","."),3994006). assertion_content_comment('oboGo_B_1BCellProliferation',s("The","expansion","of","a","B-1","B","cell","by","cell","division",".","Follows","B","cell","activation","."),4379505). assertion_content_comment('oboGo_B800_820AntennaComplex',s("Protein-pigment","complex","that","absorbs","light","at","800","and","820","nm",";","is","peripherally","associated","to","the","bacterial","reaction","center",";","transfers","excitation","energy","to","the","B875","antenna","complex","."),4052872). assertion_content_comment('oboGo_B800_850AntennaComplex',s("Protein-pigment","complex","that","absorbs","light","at","800","and","850","nm",";","is","peripherally","associated","to","the","bacterial","reaction","center",";","transfers","excitation","energy","to","the","B875","antenna","complex","."),4052858). assertion_content_comment('oboGo_Ba3Typecytochromecoxidase',s("OBSOLETE",".","Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","4","ferrocytochrome","c","+","O2","=","4","ferricytochrome","c","+","2","H2O","."),4259251). assertion_content_comment('oboGo_BacterialCatalasePeroxidaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4306043). assertion_content_comment('oboGo_BacterialTypeefPlysinemodification',s("The","modification","of","a","lysine","residue","in","a","protein",",","producing","(","2S",")","-2-amino-6-","(","[","(","3S",")","-3",",","6-diaminohexanoyl","]","amino",")","hexanoic","acid",".","This","modification","is","observed","in",",","and","is","probably","unique","to",",","the","prokaryotic","translation","elongation","factor","P","(","EF-P",")"),4125558). assertion_content_comment('oboGo_BacterialTypeferredoxin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259440). assertion_content_comment('oboGo_BacterialTypeflagellarcellmotility',s("Cell","motility","due","to","the","motion","of","one","or","more","bacterial-type","flagella",".","A","bacterial-type","flagellum","is","a","motor","complex","composed","of","an","extracellular","helical","protein","filament","coupled","to","a","rotary","motor","embedded","in","the","cell","envelope","."),4168462). assertion_content_comment('oboGo_BacterialTypeflagellarcytoplasm',s("All","of","the","contents","of","a","bacterial-type","flagellum",",","excluding","the","plasma","membrane","surrounding","the","flagellum","."),4073743). assertion_content_comment('oboGo_BacterialTypeflagellarswarmingmotility',s("Bacterial-type","flagellar","motility","in","which","the","action","of","numerous","flagella","results","in","the","smooth","movement","of","a","group","of","cells","along","a","solid","surface",".","Swarming","motility","is","observed","in","groups","of","bacteria","."),4168477). assertion_content_comment('oboGo_BacterialTypeflagellarswimmingmotility',s("Bacterial-type","flagellar","motility","that","results","in","the","smooth","movement","of","a","cell","through","a","liquid","medium","."),4168466). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodycring',s("Cytoplasmic","ring","located","at","the","base","of","the","flagellar","basal","body",";","acts","as","a","rotor",";","includes","three","switch","proteins",",","which","generate","torque","and","can","change","their","conformational","state","in","a","bimodal","fashion",",","so","that","the","motor","direction","can","switch","between","clockwise","and","counterclockwise",".","Examples","of","this","component","are","found","in","bacteria","."),4023637). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodydistalrodlring',s("One","of","the","rings","of","the","flagellar","basal","body",";","anchors","the","basal","body","to","the","outer","membrane",".","Examples","of","this","component","are","found","in","bacteria","."),4023586). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodydistalrodpring',s("One","of","the","rings","of","the","flagellar","basal","body",";","anchors","the","basal","body","to","the","peptidoglycan","layer",".","Examples","of","this","component","are","found","in","bacteria","."),4023599). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodydistalrod',s("The","portion","of","the","central","rod","of","the","flagellar","basal","body","that","is","distal","to","the","cell","membrane",";","spans","most","of","the","distance","between","the","inner","and","outer","membranes",".","Examples","of","this","component","are","found","in","bacteria","."),4023573). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodymsring',s("One","of","the","rings","of","the","flagellar","basal","body",";","a","double-flanged","ring","that","anchors","the","basal","body","to","the","cytoplasmic","membrane",".","Examples","of","this","component","are","found","in","bacteria","."),4023664). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodyproximalrod',s("The","portion","of","the","central","rod","of","the","flagellar","basal","body","that","is","proximal","to","the","cell","membrane",";","proximal","rod","connects","the","distal","rod","to","the","flagellar","motor",".","Examples","of","this","component","are","found","in","bacteria","."),4023650). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbodyrod',s("The","central","portion","of","the","flagellar","basal","body",",","which","spans","the","periplasm","and","threads","through","the","rings",".","Examples","of","this","component","are","found","in","Bacterial","species","."),4023569). assertion_content_comment('oboGo_BacterialTypeflagellumbasalbody',s("One","of","the","three","major","substructures","of","the","flagellin-based","flagellum",";","a","structure","consisting","of","a","rod",",","a","series","of","rings",",","the","Mot","proteins",",","the","switch","complex","and","the","flagellum-specific","export","apparatus",".","The","rings","anchor","the","flagellum","to","the","cytoplasmic","membrane","(","MS","ring",")",",","the","peptidoglycan","(","P","ring",")","and","the","outer","membrane","(","L","ring",")","Examples","of","this","component","are","found","in","bacteria","."),4023565). assertion_content_comment('oboGo_BacterialTypeflagellumfilamentcap',s("The","proteinaceous","structure","at","the","distal","tip","of","the","flagellar","filament",".","Examples","of","this","component","are","found","in","bacteria","."),4023624). assertion_content_comment('oboGo_BacterialTypeflagellumfilament',s("The","long","(","approximately","20","nm",")",",","thin","external","structure","of","the","flagellum",",","which","acts","as","a","propeller",".","Examples","of","this","component","are","found","in","bacteria","."),4023611). assertion_content_comment('oboGo_BacterialTypeflagellumhookFilamentjunction',s("The","region","of","the","flagellum","where","the","hook","and","filament","meet",".","Examples","of","this","component","are","found","in","bacteria","."),4258575). assertion_content_comment('oboGo_BacterialTypeflagellumhook',s("The","portion","of","the","flagellum","that","connects","the","filament","to","the","basal","body",".","Examples","of","this","component","are","found","in","bacteria","."),4258601). assertion_content_comment('oboGo_BacterialTypeflagellumpart',s("Any","constituent","part","of","flagellum",",","a","20","nm","diameter","filament","composed","of","subunits","of","flagellin","driven","passively","at","its","base","by","a","motor","powered","by","the","transmembrane","proton","potential",".","Examples","of","this","component","are","found","in","bacterial","species","."),4023544). assertion_content_comment('oboGo_BacterialTypeflagellum',s("A","motor","complex","composed","of","an","extracellular","helical","protein","filament","coupled","to","a","rotary","motor","embedded","in","the","cell","envelope","."),4023541). assertion_content_comment('oboGo_BacterialTypernapolymeraseactivity',s("Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","RNA","(","n",")","=","diphosphate","+","RNA","(","n","+","1",")","Utilizes","a","DNA","template","that","contains","a","bacterial-type","specific","promoter","to","direct","initiation","and","catalyses","DNA-template-directed","extension","of","the","3","'","-end","of","an","RNA","strand","by","one","nucleotide","at","a","time",".","Can","initiate","a","chain","'","de","novo","'"),4355933). assertion_content_comment('oboGo_BacterialTypernapolymerasecoreenzymebinding',s("Interacting","selectively","and","non-covalently","with","the","bacterial-type","RNA","polymerase","core","enzyme",",","typically","consisting","of","two","alpha",",","one","beta",",","one","beta","prime",",","and","one","omega","subunit","."),4356128). assertion_content_comment('oboGo_BacterialTypernapolymerasecorepromoterproximalregionsequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","bacterial-type","RNA","polymerase","."),4363336). assertion_content_comment('oboGo_BacterialTypernapolymerasecorepromoterproximalregionsequenceSpecificdnabindingtranscriptionfactoractivityinvolvedinnegativeregulationoftranscription',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","bacterial-type","RNA","polymerase","in","order","to","stop",",","prevent",",","or","reduce","the","frequency",",","rate","or","extent","of","transcription","from","a","bacterial-type","RNA","polymerase","promoter","."),4358275). assertion_content_comment('oboGo_BacterialTypernapolymerasecorepromoterproximalregionsequenceSpecificdnabindingtranscriptionfactoractivityinvolvedinpositiveregulationoftranscription',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","bacterial-type","RNA","polymerase","in","order","to","modulate","transcription","by","bacterial-type","RNA","polymerase",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex","."),4358284). assertion_content_comment('oboGo_BacterialTypernapolymerasecorepromoterproximalregionsequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","bacterial-type","RNA","polymerase","in","order","to","modulate","transcription","by","bacterial-type","RNA","polymerase",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex","."),4358273). assertion_content_comment('oboGo_BacterialTypernapolymerasecorepromotersequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","specific","DNA","sequence","in","a","bacterial-type","RNA","polymerase","core","promoter",",","the","region","composed","of","the","transcription","start","site","and","binding","sites","for","transcription","factors","of","the","basal","transcription","machinery",",","in","order","to","modulate","transcription",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex","."),4363387). assertion_content_comment('oboGo_BacterialTypernapolymeraseenhancersequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","an","enhancer","region","that","helps","activate","transcription","of","a","gene","or","operon","by","a","bacterial-type","RNA","polymerase",".","Enhancers","for","sigma-54","holoenzymes","are","typically","located","80","to","150","base","pairs","upstream","from","the","transcription","start","site",".","Some","transcription","units","dependent","on","sigma-70","holoenzymes","may","also","include","enhancer","sequences","."),4357973). assertion_content_comment('oboGo_BacterialTypernapolymeraseholoenzymebinding',s("Interacting","selectively","and","non-covalently","with","the","basal","transcription","machinery","which","is","composed","of","a","bacterial-type","RNA","polymerase","core","enzyme","and","a","sigma","factor",",","the","minimal","set","of","factors","required","for","formation","of","the","preinitiation","complex","(","PIC",")","by","a","bacterial-type","RNA","polymerase","."),4358177). assertion_content_comment('oboGo_BacterialTypernapolymerasepreinitiationcomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","proteins","on","a","bacterial-type","RNA","polymerase","promoter","DNA","to","form","the","transcriptional","preinitiation","complex","(","PIC",")",",","the","formation","of","which","is","a","prerequisite","for","transcription","by","RNA","polymerase","."),3980601). assertion_content_comment('oboGo_BacterialTypernapolymeraseregulatoryregiondnabinding',s("Interacting","selectively","and","non-covalently","with","a","DNA","region","that","controls","the","transcription","of","a","gene","or","operon","by","a","bacterial-type","RNA","polymerase",".","Binding","may","occur","as","a","sequence","specific","interaction","or","as","an","interaction","observed","only","once","a","factor","has","been","recruited","to","the","DNA","by","other","factors","."),4356842). assertion_content_comment('oboGo_BacterialTypernapolymeraseregulatoryregionsequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","part","of","a","regulatory","region","that","controls","the","transcription","of","a","gene","or","operon","by","a","bacterial-type","RNA","polymerase","."),4357969). assertion_content_comment('oboGo_BacterialTypernapolymeraseterminationsitesequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","a","terminator","for","bacterial-type","RNA","polymerase","."),4358376). assertion_content_comment('oboGo_BacterialTypernapolymeraseterminationsitesequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","a","termination","site","for","bacterial-type","RNA","polymerase","in","order","to","promote","transcription","termination","by","bacterial-type","RNA","polymerase","."),4358366). assertion_content_comment('oboGo_BacterialTypernapolymerasetranscriptionenhancersequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","a","bacterial-type","enhancer","region","in","order","to","activate","transcription","by","bacterial-type","RNA","polymerase",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex",".","Enhancers","for","sigma-54","holoenzymes","are","typically","located","80","to","150","base","pairs","upstream","from","the","transcription","start","site",".","Some","transcription","units","dependent","on","sigma-70","holoenzymes","may","also","include","enhancer","sequences","."),4357991). assertion_content_comment('oboGo_BacteriocinTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","drives","the","transport","of","bacteriocins","across","a","membrane","."),4318636). assertion_content_comment('oboGo_BacteroidContainingsymbiosome',s("A","symbiosome","containing","any","of","various","structurally","modified","bacteria",",","such","as","those","occurring","on","the","root","nodules","of","leguminous","plants","."),4094939). assertion_content_comment('oboGo_BarbedEndactincappingactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4193216). assertion_content_comment('oboGo_BarbedEndactincappingseveringactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4193228). assertion_content_comment('oboGo_BarbedEndactinfilamentcapping',s("The","binding","of","a","protein","or","protein","complex","to","the","barbed","(","or","plus",")","end","of","an","actin","filament",",","thus","preventing","the","addition",",","exchange","or","removal","of","further","actin","subunits","."),4193198). assertion_content_comment('oboGo_BarbedEndactinfilamentuncapping',s("The","removal","of","capping","protein","from","the","barbed","(","or","plus",")","end","of","actin","filaments","to","free","the","ends","for","addition",",","exchange","or","removal","of","further","actin","subunits","."),4285208). assertion_content_comment('oboGo_BasalLayerOfCollagenAndCuticulinBasedcuticleextracellularmatrix',s("The","layer","of","cuticle","most","closely","apposed","to","the","hypodermal","cells",".","The","morphology","of","the","basal","layer","varies","with","life","stage",".","In","adult","C",".","elegans","animals",",","the","basal","layers","is","comprised","of","three","sublayers",":","two","fibrous","layers","whose","fibers","run","in","clockwise","and","counter-clockwise","directions","meeting","one","another","at","a","60","degree","angle",",","and","an","amorphous","basal","layer","that","lies","underneath","the","fibrous","layers","and","directly","contacts","the","hypodermis",".","In","C",".","elegans","dauer","and","L1","larval","stage","animals",",","the","basal","layer","is","characterized","by","a","striated","pattern","that","appears","to","derive","from","interwoven","laminae",".","An","example","of","this","component","is","found","in","Caenorhabditis","elegans","."),4108890). assertion_content_comment('oboGo_BaseExcisionrepairapsiteformation',s("The","formation","of","an","AP","site",",","a","deoxyribose","sugar","with","a","missing","base",",","by","DNA","glycosylase","which","recognizes","an","altered","base","in","DNA","and","catalyzes","its","hydrolytic","removal",".","This","sugar","phosphate","is","the","substrate","recognized","by","the","AP","endonuclease",",","which","cuts","the","DNA","phosphodiester","backbone","at","the","5","'","side","of","the","altered","site","to","leave","a","gap","which","is","subsequently","repaired","."),4011015). assertion_content_comment('oboGo_BaseExcisionrepairbaseFreesugarPhosphateremoval',s("Excision","of","the","sugar","phosphate","residue","at","an","AP","site",",","i.e",".","a","deoxyribose","sugar","with","a","missing","base",",","by","a","phosphodiesterase","enzyme","."),4011004). assertion_content_comment('oboGo_BaseExcisionrepairdnaligation',s("The","ligation","by","DNA","ligase","of","DNA","strands",".","Ligation","occurs","after","polymerase","action","to","fill","the","gap","left","by","the","action","of","endonucleases","during","base-excision","repair","."),4011060). assertion_content_comment('oboGo_BaseExcisionrepairgapFilling',s("Repair","of","the","damaged","strand","by","the","combined","action","of","an","apurinic","endouclease","that","degrades","a","few","bases","on","the","damaged","strand","and","a","polymerase","that","synthesizes","a","'","patch","'","in","the","5","'","to","3","'","direction",",","using","the","undamaged","strand","as","a","template","."),4011026). assertion_content_comment('oboGo_BaseExcisionrepair',s("In","base","excision","repair",",","an","altered","base","is","removed","by","a","DNA","glycosylase","enzyme",",","followed","by","excision","of","the","resulting","sugar","phosphate",".","The","small","gap","left","in","the","DNA","helix","is","filled","in","by","the","sequential","action","of","DNA","polymerase","and","DNA","ligase","."),4010981). assertion_content_comment('oboGo_BCellToleranceInductionInMucosalAssociatedlymphoidtissue',s("Tolerance","induction","taking","place","in","the","mucosal-associated","lymphoid","tissue","(","MALT",")","mediated","by","B","cells","."),4381380). assertion_content_comment('oboGo_Bcl3Bcl10complex',s("A","protein","complex","containing","Bcl3","and","Bcl10",",","which","forms","when","Akt1","is","activated","by","TNF-alpha","to","phosphorylate","Bcl10",";","the","Bcl3-Bcl10","complex","is","translocated","to","the","nucleus","."),4336890). assertion_content_comment('oboGo_Bcl3NFKappab2complex',s("A","protein","complex","containing","one","Bcl","protein","and","one","or","more","copies","of","NF-kappaB2",";","formation","of","complexes","of","different","stoichiometry","depends","on","the","Bcl3",":","NF-kappaB2","ratio",",","and","allow","Bcl3","to","exert","different","regulatory","effects","on","NF-kappaB2-dependent","transcription","."),4337886). assertion_content_comment('oboGo_BentDNABinding_6',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4222518). assertion_content_comment('oboGo_Benzene12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzene","+","H","(","+",")","+","NADH","+","O","(","2",")","=","cis-cyclohexa-3",",","5-diene-1",",","2-diol","+","NAD","(","+",")"),4275999). assertion_content_comment('oboGo_BenzeneContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","benzene",",","C6H6",",","a","volatile",",","very","inflammable","liquid",",","contained","in","the","naphtha","produced","by","the","destructive","distillation","of","coal",",","from","which","it","is","separated","by","fractional","distillation",",","or","any","of","its","derivatives","."),3991994). assertion_content_comment('oboGo_BenzoAPyrene1112Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene","+","O2","=","benzo","(","a",")","pyrene-cis-11",",","12-dihydrodiol","."),4349013). assertion_content_comment('oboGo_BenzoAPyrene1112Epoxidaseactivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene","+","O2","=","benzo","(","a",")","pyrene-11",",","12-epoxide","."),4349031). assertion_content_comment('oboGo_BenzoAPyrene45Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene","+","O2","=","benzo","(","a",")","pyrene-cis-4",",","5-dihydrodiol","."),4348995). assertion_content_comment('oboGo_BenzoAPyrene78Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene","+","O2","=","benzo","(","a",")","pyrene-cis-7",",","8-dihydrodiol","."),4350475). assertion_content_comment('oboGo_BenzoAPyrene910Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene","+","O2","=","benzo","(","a",")","pyrene-cis-9",",","10-dihydrodiol","."),4350493). assertion_content_comment('oboGo_BenzoAPyrene_Cis_45_DihydrodiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene-cis-4",",","5-dihydrodiol","=","4",",","5-dihydroxybenzo","(","a",")","pyrene","+","H2","."),4348986). assertion_content_comment('oboGo_BenzoAPyrene_Trans_1112_DihydrodiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","benzo","(","a",")","pyrene-trans-11",",","12-dihydrodiol","=","11",",","12-dihydroxybenzo","(","a",")","pyrene","+","2","H","+","+","2","e-","."),4349022). assertion_content_comment('oboGo_Benzoate12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzoate","+","NADH","+","H","+","+","O2","=","catechol","+","CO2","+","NAD","+"),4276089). assertion_content_comment('oboGo_Benzoate4Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","benzoate","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","4-hydroxybenzoate","+","H","(","2",")","O","+","NADP","(","+",")"),4276485). assertion_content_comment('oboGo_BenzoateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","benzoate","+","CoA","=","AMP","+","benzoyl-CoA","+","diphosphate","+","H","(","+",")"),4273798). assertion_content_comment('oboGo_Benzothiazole_2_SulfonateHydrolaseActivity',s("Catalysis","of","the","reaction",":","benzothiazole-2-sulfonate","+","H2O","=","2-hydroxybenzothiazole","+","HSO3-","."),4350920). assertion_content_comment('oboGo_BenzoylAcetateCoaligaseactivity',s("Catalysis","of","the","reaction",":","3-oxo-3-phenylpropionate","+","CoA","+","ATP","=","AMP","+","diphosphate","+","benzoyl","acetyl-CoA","."),4273741). assertion_content_comment('oboGo_BenzoylAcetateCoathiolaseactivity',s("Catalysis","of","the","reaction",":","benzoyl","acetyl-CoA","+","CoA","=","acetyl-CoA","+","benzoyl-CoA","."),4275283). assertion_content_comment('oboGo_BenzoylCoa3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","benzoyl-CoA","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","3-hydroxybenzoyl-CoA","+","H","(","2",")","O","+","NADP","(","+",")"),4364545). assertion_content_comment('oboGo_BenzoylCoareductaseactivity',s("Catalysis","of","the","reaction",":","benzoyl-CoA","+","donor-H2","+","2","ATP","=","cyclohexa-1",",","5-diene-1-carbonyl-CoA","+","acceptor","+","2","ADP","+","2","phosphate","."),4278339). assertion_content_comment('oboGo_Benzyl_2_Methyl_HydroxybutyrateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","benzyl","(","2R",",","3S",")","-2-methyl-3-hydroxybutanoate","+","NADP","(","+",")","=","benzyl","2-methyl-3-oxobutanoate","+","H","(","+",")","+","NADPH","."),4363985). assertion_content_comment('oboGo_Beta_123456_HexachlorocyclohexaneMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","beta-1",",","2",",","3",",","4",",","5",",","6-hexachlorocyclohexane",",","a","halogenated","organic","insecticide","that","has","been","used","worldwide","for","agriculture","and","public","health","."),4273154). assertion_content_comment('oboGo_Beta_12_OligomannosideBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-1",",","2-linked","oligomannosides",",","which","are","found","in","fungal","cell","wall","phosphopeptidomannan","and","phospholipomannan","."),4179658). assertion_content_comment('oboGo_Beta_12_OligomannosideMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","beta-1",",","2-linked","oligomannosides",",","which","are","found","in","fungal","cell","wall","phosphopeptidomannan","and","phospholipomannan","."),4179655). assertion_content_comment('oboGo_Beta_13_Galactosyl_O_Glycosyl_GlycoproteinBeta_13_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","beta-D-galactosyl-1",",","3-","(","N-acetyl-D-glucosaminyl-1",",","6",")","-N-acetyl-D-galactosaminyl-R","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","3-","(","N-acetyl-beta-D-glucosaminyl-1",",","6",")","-N-acetyl-D-galactosaminyl-R","+","UDP","."),4366473). assertion_content_comment('oboGo_Beta_13_Galactosyl_O_Glycosyl_GlycoproteinBeta_16_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-galactosyl-1",",","3-N-acetyl-D-galactosaminyl-R","=","UDP","+","beta-D-galactosyl-1",",","3-","(","N-acetyl-beta-D-glucosaminyl-1",",","6",")","-N-acetyl-D-galactosaminyl-R","."),4188483). assertion_content_comment('oboGo_Beta_13_GalactosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","galactose","residue","from","a","donor","molecule","to","an","oligosaccharide",",","forming","a","beta-1",",","3-linkage","."),4254417). assertion_content_comment('oboGo_Beta_14_MannosylglycolipidBeta_13_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","transfer","of","N-acetylglucosamine","(","GlcNAc",")","in","a","beta-1",",","3","linkage","to","the","mannose","(","beta-1",",","4",")","Glc","disaccharide","core","of","glycolipids","."),4361746). assertion_content_comment('oboGo_Beta_14_Mannosylglycoprotein4_Beta_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-mannosyl-R","=","UDP","+","4-","(","N-acetyl-beta-D-glucosaminyl",")","-beta-D-mannosyl-R","."),4188222). assertion_content_comment('oboGo_Beta_14_MannosyltransferaseActivity',s("Catalysis","of","the","transfer","of","a","mannose","residue","from","GDP-mannose","to","an","oligosaccharide",",","forming","a","beta-1",",","4-linkage","."),4204324). assertion_content_comment('oboGo_Beta_14_N_AcetylgalactosaminyltransferaseActivity',s("Catalysis","of","the","transfer","of","an","N-acetylgalactosaminyl","residue","from","UDP-N-acetyl-galactosamine","to","an","acceptor","molecule",",","forming","a","beta-1",",","4","linkage","."),4338092). assertion_content_comment('oboGo_Beta1Adrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","beta1-adrenergic","receptors","."),4197964). assertion_content_comment('oboGo_Beta_1AdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","a","beta-1","adrenergic","receptor","."),4322521). assertion_content_comment('oboGo_Beta2Adrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","beta2-adrenergic","receptors","."),4197954). assertion_content_comment('oboGo_Beta_2AdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","a","beta-2","adrenergic","receptor","."),4322471). assertion_content_comment('oboGo_Beta_2_MicroglobulinBinding',s("Interacting","selectively","and","non-covalently","with","beta-2-microglobulin","."),4307121). assertion_content_comment('oboGo_Beta3Adrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","beta3-adrenergic","receptors","."),4297252). assertion_content_comment('oboGo_Beta_3AdrenergicReceptorBinding',s("Interacting","selectively","and","non-covalently","with","a","beta-3","adrenergic","receptor","."),4322481). assertion_content_comment('oboGo_BetaActininbinding',s("Interacting","selectively","and","non-covalently","with","beta-actinin",",","a","heterodimeric","actin-binding","protein","which","caps","the","barbed","end","of","actin","filaments","and","nucleates","actin","polymerization","in","a","calcium-independent","manner",".","In","myofibrils","it","is","localized","in","the","Z-lines","."),4286844). assertion_content_comment('oboGo_BetaAdrenergicreceptoractivity',s("Combining","with","epinephrine","or","norepinephrine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein",",","with","pharmacological","characteristics","of","beta-adrenergic","receptors",";","the","activity","involves","transmitting","the","signal","to","the","Gs","alpha","subunit","of","a","heterotrimeric","G","protein","."),4197869). assertion_content_comment('oboGo_BetaAdrenergicreceptorkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","beta-adrenergic","receptor","=","ADP","+","phospho-beta-adrenergic","receptor","."),4371800). assertion_content_comment('oboGo_BetaAgaraseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-beta-D-galactosidic","linkages","in","agarose",",","giving","the","tetramer","as","the","predominant","product","."),4344276). assertion_content_comment('oboGo_BetaAlaninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-alanine","(","3-aminopropanoic","acid",")",",","an","achiral","amino","acid","and","an","isomer","of","alanine",".","It","occurs","free","(","e.g",".","in","brain",")","and","in","combination","(","e.g",".","in","pantothenate",")","but","it","is","not","a","constituent","of","proteins","."),4241212). assertion_content_comment('oboGo_BetaAlaninebiosyntheticprocessvia13diaminopropane',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-alanine","via","the","intermediate","1",",","3","diaminopropane","."),4338540). assertion_content_comment('oboGo_BetaAlaninebiosyntheticprocessvia3Hydroxypropionate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-alanine","via","the","intermediate","3-hydroxypropionate","."),4338457). assertion_content_comment('oboGo_BetaAlaninebiosyntheticprocessvia3Ureidopropionate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-alanine","via","the","intermediate","3-ureidopropionate","."),4338445). assertion_content_comment('oboGo_BetaAlaninecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","beta-alanine","(","3-aminopropanoic","acid",")",",","an","achiral","amino","acid","and","an","isomer","of","alanine",".","It","occurs","free","(","e.g",".","in","brain",")","and","in","combination","(","e.g",".","in","pantothenate",")","but","it","is","not","a","constituent","of","proteins","."),4241227). assertion_content_comment('oboGo_BetaAlaninecatabolicprocesstolAlanine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","beta-alanine","into","other","compounds",",","including","L-alanine","."),4241241). assertion_content_comment('oboGo_BetaAlaninecatabolicprocesstomevalonatesemialdehydebytransamination',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","beta-alanine","into","other","compounds",",","including","mevalonate","semialdehyde",",","by","transamination","."),4241253). assertion_content_comment('oboGo_BetaAlaninemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-alanine","(","3-aminopropanoic","acid",")",",","an","achiral","amino","acid","and","an","isomer","of","alanine",".","It","occurs","free","(","e.g",".","in","brain",")","and","in","combination","(","e.g",".","in","pantothenate",")","but","it","is","not","a","constituent","of","proteins","."),4241059). assertion_content_comment('oboGo_BetaAlaninePyruvatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-alanine","+","2-oxopropanoate","=","pyruvate","+","beta-alanine","."),4303779). assertion_content_comment('oboGo_BetaAlaninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","beta-alanine","from","one","side","of","a","membrane","to","the","other",".","Beta-alanine","is","3-aminopropanoic","acid","."),4383459). assertion_content_comment('oboGo_BetaAlaninetransport',s("The","directed","movement","of","beta-alanine",",","3-aminopropanoic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4383450). assertion_content_comment('oboGo_BetaAlanopinedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-beta-alanopine","+","H","(","2",")","O","+","NAD","(","+",")","=","beta-alanine","+","H","(","+",")","+","NADH","+","pyruvate","."),4371762). assertion_content_comment('oboGo_BetaAlanylCoaammoniaLyaseactivity',s("Catalysis","of","the","reaction",":","beta-alanyl-CoA","=","acryloyl-CoA","+","NH3","."),4371773). assertion_content_comment('oboGo_BetaAlanylDopaminehydrolaseactivity',s("Catalysis","of","the","conversion","of","beta-alanyl","dopamine","to","dopamine","(","3",",","4-dihydroxyphenylethylamine",")"),4188239). assertion_content_comment('oboGo_BetaAlanylDopaminesynthaseactivity',s("Catalysis","of","the","synthesis","of","beta-alanyl-dopamine","from","the","precursor","dopamine","(","3",",","4-dihydroxyphenylethylamine",")"),4188311). assertion_content_comment('oboGo_BetaAlanylHistaminehydrolaseactivity',s("Catalysis","of","the","conversion","of","beta-alanyl-histamine","to","histamine","."),4320522). assertion_content_comment('oboGo_BetaAmylaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-alpha-glucosidic","linkages","in","polysaccharides","so","as","to","remove","successive","maltose","units","from","the","non-reducing","ends","of","the","chains","."),4304205). assertion_content_comment('oboGo_BetaAmyloidbinding',s("Interacting","selectively","and","non-covalently","with","beta-amyloid","peptide/protein","and/or","its","precursor","."),4361596). assertion_content_comment('oboGo_BetaAmyloidformation',s("The","generation","of","beta-amyloid","by","cleavage","of","the","amyloid","precursor","protein","(","APP",")"),4359891). assertion_content_comment('oboGo_BetaAmyloidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-amyloid",",","a","glycoprotein","associated","with","Alzheimer","'","s","disease",",","and","its","precursor",",","amyloid","precursor","protein","(","APP",")"),4266990). assertion_content_comment('oboGo_BetaAmyrinsynthaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-2",",","3-epoxysqualene","=","beta-amyrin",".","This","reaction","is","the","cyclization","and","rearrangement","of","(","S",")","-2",",","3-epoxysqualene","(","2",",","3-oxidosqualene",")","into","beta-amyrin","."),4314033). assertion_content_comment('oboGo_BetaApiosylBetaGlucosidaseactivity',s("Catalysis","of","the","reaction",":","7-","[","beta-D-apiofuranosyl-","(","1-","&","gt",";","6",")","-beta-D-glucopyranosyloxy","]","isoflavonoid","+","H2O","=","a","7-hydroxyisoflavonoid","+","beta-D-apiofuranosyl-","(","1-","&","gt",";","6",")","-D-glucose","."),4344529). assertion_content_comment('oboGo_BetaAspartylNAcetylglucosaminidaseactivity',s("Catalysis","of","the","reaction",":","N","(","4",")","-","(","beta-N-acetyl-D-glucosaminyl",")","-L-asparagine","+","H","(","2",")","O","=","N-acetyl-D-glucosamine","+","L-asparagine","."),4369967). assertion_content_comment('oboGo_BetaAspartylPeptidaseactivity',s("Catalysis","of","the","cleavage","of","a","beta-linked","aspartic","residue","from","the","N-terminus","of","a","polypeptide","."),4248985). assertion_content_comment('oboGo_BetaBeta_Carotene_910_DioxygenaseActivity',s("Catalysis","of","the","reaction",":","beta-carotene","+","O2","=","beta-apo-10","'","-carotenal","+","beta-ionone","."),4268873). assertion_content_comment('oboGo_BetaCarotene1515Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","beta-carotene","+","O","(","2",")","=","2","retinal","."),4188298). assertion_content_comment('oboGo_BetaCarotene3Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","beta-carotene","+","a","reduced","electron","acceptor","+","oxygen","=","beta-cryptoxanthin","+","an","oxidized","electron","acceptor","+","H2O","."),4191079). assertion_content_comment('oboGo_BetaCateninbinding',s("Interacting","selectively","and","non-covalently","with","the","beta","subunit","of","the","catenin","complex","."),4247408). assertion_content_comment('oboGo_BetaCatenindestructioncomplex',s("A","cytoplasmic","protein","complex","containing","glycogen","synthase","kinase-3-beta","(","GSK-3-beta",")",",","the","adenomatous","polyposis","coli","protein","(","APC",")",",","and","the","scaffolding","protein","axin",",","among","others",";","phosphorylates","beta-catenin",",","targets","it","for","degradation","by","the","proteasome","."),4307140). assertion_content_comment('oboGo_BetaCateninTcf7l2complex',s("A","protein","complex","that","contains","beta-catenin","and","TCF7L2","(","TCF4",")",",","binds","to","the","TCF","DNA","motif","within","a","promoter","element",",","and","is","involved","in","the","regulation","of","WNT","target","gene","transcription","."),4173310). assertion_content_comment('oboGo_BetaCryptoxanthinhydroxylaseactivity',s("Catalysis","of","the","reaction",":","beta-cryptoxanthin","+","a","reduced","electron","acceptor","+","oxygen","=","zeaxanthin","+","an","oxidized","electron","acceptor","+","H2O","."),4191067). assertion_content_comment('oboGo_BetaCyclopiazonatedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","beta-cyclopiazonate","+","A","=","alpha-cyclopiazonate","+","AH","(","2",")"),4267131). assertion_content_comment('oboGo_BetaDFucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","beta-D-fucose","residues","in","beta-D-fucosides","."),4344112). assertion_content_comment('oboGo_BetaDiketonehydrolaseactivity',s("Catalysis","of","the","reaction",":","H","(","2",")","O","+","nonane-4",",","6-dione","=","butanoate","+","H","(","+",")","+","pentan-2-one","."),4371830). assertion_content_comment('oboGo_BetaDystroglycanbinding',s("Interacting","selectively","and","non-covalently","with","beta-dystroglycan",".","Beta-dystroglycan","is","a","transmembrane","protein","derived","from","cleavage","of","dystroglycan","."),4376061). assertion_content_comment('oboGo_BetaEndorphinbinding',s("Interacting","selectively","and","non-covalently","with","beta-endorphin",",","a","peptide","generated","by","the","cleavage","of","pro-opiomelanocortin","."),4322298). assertion_content_comment('oboGo_BetaEndorphinreceptoractivity',s("Combining","with","beta-endorphin","to","initiate","a","change","in","cell","activity","."),4198950). assertion_content_comment('oboGo_BetaEndorphinreceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","beta-endorphin","receptor","."),4170974). assertion_content_comment('oboGo_BetaFructofuranosidaseactivity',s("Catalysis","of","the","reaction",":","a","fructofuranosylated","fructofuranosyl","acceptor","+","H2O","=","a","non","fructofuranosylated","fructofuranosyl","acceptor","+","a","beta-D-fructofuranoside","."),4204371). assertion_content_comment('oboGo_BetaGalactofuranosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","beta-D-galactofuranosides",",","releasing","galactose","."),4344443). assertion_content_comment('oboGo_BetaGalactosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","beta-D-galactose","residues","in","beta-D-galactosides","."),4204555). assertion_content_comment('oboGo_BetaGalactosidasecomplex',s("A","protein","complex","that","possesses","beta-galactosidase","activity",",","i.e",".","catalyzes","the","hydrolysis","of","terminal","non-reducing","beta-D-galactose","residues","in","beta-D-galactosides",".","In","E",".","coli",",","the","complex","is","a","homotetramer",";","dimeric","and","hexameric","beta-galactosidase","complexes","have","been","observed","in","other","species","."),4259647). assertion_content_comment('oboGo_BetaGalactosidasestabilizationactivity',s("OBSOLETE",".","Stabilization","of","the","structure","of","beta-galactosidase","."),4268496). assertion_content_comment('oboGo_Beta_GalactosideAlpha_23_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","beta-D-galactosyl-1",",","3-N-acetyl-alpha-D-galactosaminyl-R","=","CMP","+","alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-1",",","3-N-acetyl-alpha-D-galactosaminyl-R","."),4188757). assertion_content_comment('oboGo_Beta_GalactosideAlpha_26_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","beta-D-galactosyl-1",",","4-acetyl-beta-D-glucosamine","=","CMP","+","alpha-N-acetylneuraminyl-2",",","6-beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosamine","."),4188745). assertion_content_comment('oboGo_Beta_Galactosyl_N_Acetylglucosaminylgalactosylglucosyl_CeramideBeta_13_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","=","UDP","+","N-acetyl-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","."),4253898). assertion_content_comment('oboGo_BetaGentiobiosebetaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","glucosidic","link","in","beta-gentiobiose","."),4182388). assertion_content_comment('oboGo_BetaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-glucans","."),4063916). assertion_content_comment('oboGo_BetaGlucancatabolicprocessinvolvedinascosporereleasefromascus',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","beta-glucans","in","the","ascus","wall","that","contributes","to","the","release","of","ascospores","from","the","ascus","."),4158638). assertion_content_comment('oboGo_BetaGlucancatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","beta-glucans","."),4158632). assertion_content_comment('oboGo_BetaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds","."),4063891). assertion_content_comment('oboGo_BetaGlucantransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","beta-glucans","from","one","side","of","the","membrane","to","the","other",".","Beta-glucans","are","compounds","composed","of","glucose","residues","linked","by","beta-glucosidic","bonds","."),4292033). assertion_content_comment('oboGo_BetaGlucanTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","beta-glucan","(","in",")","=","ADP","+","phosphate","+","beta-glucan","(","out",")"),4292036). assertion_content_comment('oboGo_BetaGlucantransport',s("The","directed","movement","of","beta-glucans","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Beta-glucans","are","compounds","composed","of","glucose","residues","linked","by","beta-glucosidic","bonds","."),4291271). assertion_content_comment('oboGo_BetaGlucogallinoGalloyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","1-O-galloyl-beta-D-glucose","=","1",",","6-bis-O-galloyl-beta-D-glucose","+","D-glucose","."),4367766). assertion_content_comment('oboGo_BetaGlucogallinTetrakisgalloylglucoseoGalloyltransferaseactivity',s("Catalysis","of","the","reaction",":","1",",","2",",","3",",","6-tetrakis-O-galloyl-beta-D-glucose","+","1-O-galloyl-beta-D-glucose","=","1",",","2",",","3",",","4",",","6-pentakis-O-galloyl-beta-D-glucose","+","D-glucose","."),4366426). assertion_content_comment('oboGo_BetaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","beta-D-glucose","residues","with","release","of","beta-D-glucose","."),4182368). assertion_content_comment('oboGo_BetaGlucosidearbutinSalicinCellobiosepermeaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","protein","N-phosphohistidine","+","beta-glucoside","(","out",")","=","protein","histidine","+","beta-glucoside","phosphate","(","in",")","The","beta-glucoside","may","be","arbutin",",","salicin","or","cellobiose","."),4293587). assertion_content_comment('oboGo_BetaGlucosidekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","cellobiose","=","ADP","+","6-phospho-beta-D-glucosyl-","(","1",",","4",")","-D-glucose","."),4374520). assertion_content_comment('oboGo_BetaGlucosidetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","beta-glucosides","from","one","side","of","the","membrane","to","the","other",".","Beta-glucosides","are","glycosides","in","which","the","sugar","group","is","a","glucose","residue",",","and","the","anomeric","carbon","of","the","bond","is","in","a","beta","configuration","."),4293576). assertion_content_comment('oboGo_BetaGlucosidetransport',s("The","directed","movement","of","beta-glucosides","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Beta-glucosides","are","glycosides","in","which","the","sugar","group","is","a","glucose","residue",",","and","the","anomeric","carbon","of","the","bond","is","in","a","beta","configuration","."),4291212). assertion_content_comment('oboGo_BetaGlucuronidaseactivity',s("Catalysis","of","the","reaction",":","a","beta-D-glucuronoside","+","H2O","=","an","alcohol","+","D-glucuronate","."),4204578). assertion_content_comment('oboGo_BetaHeterochromatin',s("A","diffusely","banded","region","of","heterochromatin","located","between","euchromatin","and","alpha-heterochromatin","in","the","polytene","chromosome","chromocenter",";","normally","replicated","during","polytenization","."),4007881). assertion_content_comment('oboGo_BetaineAldehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","betaine","aldehyde","+","NAD","+","+","H2O","=","betaine","+","NADH","+","H","+"),4250520). assertion_content_comment('oboGo_BetaineHomocysteinesMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-homocysteine","+","betaine","=","N",",","N-dimethylglycine","+","L-methionine","."),4365408). assertion_content_comment('oboGo_BetaineTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","a","betaine","(","out",")","=","ADP","+","phosphate","+","a","betaine","(","in",")"),4321466). assertion_content_comment('oboGo_BetaKetoacylAcylCarrierProteinsynthaseiiactivity',s("Catalysis","of","the","reaction",":","(","Z",")","-hexadec-11-enoyl-","[","acyl-carrier","protein","]","+","malonyl-","[","acyl-carrier","protein","]","=","(","Z",")","-3-oxooctadec-13-enoyl-","[","acyl-carrier","protein","]","+","CO2","+","[","acyl-carrier","protein","]"),4343064). assertion_content_comment('oboGo_BetaKetoacylAcylCarrierProteinsynthaseiiiactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","malonyl-","[","acyl-carrier","protein","]","=","acetoacyl-","[","acyl-carrier","protein","]","+","CoA","+","CO2","."),4342996). assertion_content_comment('oboGo_BetaKetoadipatepathway',s("A","pathway","of","aromatic","compound","degradation","by","ortho-cleavage",";","one","branch","converts","protocatechuate",",","derived","from","phenolic","compounds",",","to","beta-ketoadipate",",","and","the","other","branch","converts","catechol",",","generated","from","various","aromatic","hydrocarbons",",","amino","aromatics",",","and","lignin","monomers",",","also","to","beta-ketoadipate",".","Two","additional","steps","accomplish","the","conversion","of","beta-ketoadipate","to","tricarboxylic","acid","cycle","intermediates","."),4243816). assertion_content_comment('oboGo_BetaLactamantibioticbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","beta-lactam","antibiotic",",","any","member","of","a","class","of","natural","or","semisynthetic","antibiotics","whose","characteristic","feature","is","a","strained",",","four-membered","beta-lactam","ring",".","They","include","the","penicillins","and","many","of","the","cephalosporins","."),4308213). assertion_content_comment('oboGo_BetaLactamantibioticcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","beta-lactam","antibiotic",",","any","member","of","a","class","of","natural","or","semisynthetic","antibiotics","whose","characteristic","feature","is","a","strained",",","four-membered","beta-lactam","ring",".","They","include","the","penicillins","and","many","of","the","cephalosporins","."),4066667). assertion_content_comment('oboGo_BetaLactamantibioticmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","beta-lactam","antibiotic",",","any","member","of","a","class","of","natural","or","semisynthetic","antibiotics","whose","characteristic","feature","is","a","strained",",","four-membered","beta-lactam","ring",".","They","include","the","penicillins","and","many","of","the","cephalosporins","."),4066638). assertion_content_comment('oboGo_BetaLactamaseactivity',s("Catalysis","of","the","reaction",":","a","beta-lactam","+","H2O","=","a","substituted","beta-amino","acid","."),4250488). assertion_content_comment('oboGo_BetaLArabinosidaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","a","beta-L-arabinoside","=","L-arabinose","+","an","alcohol","."),4374546). assertion_content_comment('oboGo_BetaLRhamnosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","beta-L-rhamnose","residues","in","beta-L-rhamnosides","."),4344123). assertion_content_comment('oboGo_BetaLysine56Aminomutaseactivity',s("Catalysis","of","the","reaction",":","(","3S",")","-3",",","6-diaminohexanoate","=","(","3S",",","5S",")","-3",",","5-diaminohexanoate","."),4374533). assertion_content_comment('oboGo_BetaMannosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","beta-D-mannose","residues","in","beta-D-mannosides","."),4204593). assertion_content_comment('oboGo_BetaMannosylphosphodecaprenolMannooligosaccharide6Mannosyltransferaseactivity',s("Catalysis","of","the","reaction",":","1",",","6-alpha-D-mannosyloligodaccharide","+","beta-D-mannosylphosphodecaprenol","=","1",",","6-alpha-D-mannosyl-1",",","6-alpha-D-mannosyl-oligosaccharide","+","decaprenol","phosphate","."),4367216). assertion_content_comment('oboGo_BetaMitochondrialprocessingpeptidase',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4210239). assertion_content_comment('oboGo_BetaNAcetylgalactosaminidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","N-acetyl-D-galactosamine","residues","in","N-acetyl-beta-D-galactosaminides","."),4334997). assertion_content_comment('oboGo_BetaNAcetylglucosaminidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","N-acetyl-D-glucosamine","residues","in","N-acetyl-beta-D-glucosaminides","."),4303802). assertion_content_comment('oboGo_Beta_N_AcetylglucosaminylglycopeptideBeta_14_GalactosyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","N-acetyl-beta-D-glucosaminylglycopeptide","=","UDP","+","beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminylglycopeptide","."),4188250). assertion_content_comment('oboGo_BetaNAcetylhexosaminidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","non-reducing","N-acetyl-D-hexosamine","residues","in","N-acetyl-beta-D-hexosaminides","."),4204646). assertion_content_comment('oboGo_BetaNitroacrylatereductaseactivity',s("Catalysis","of","the","reaction",":","3-nitropropanoate","+","NADP","(","+",")","=","3-nitroacrylate","+","H","(","+",")","+","NADPH","."),4374399). assertion_content_comment('oboGo_BetaPhosphoglucomutaseactivity',s("Catalysis","of","the","reaction",":","beta-D-glucose","1-phosphate","=","beta-D-glucose","6-phosphate","."),4250509). assertion_content_comment('oboGo_BetaPrimeverosidaseactivity',s("Catalysis","of","the","reaction",":","a","6-O-","(","beta-D-xylopyranosyl",")","-beta-D-glucopyranoside","+","H2O","=","6-O-","(","beta-D-xylopyranosyl",")","-beta-D-glucopyranose","+","an","alcohol","."),4268613). assertion_content_comment('oboGo_BetaPyrazolylalaninesynthaseactivity',s("Catalysis","of","the","reaction",":","O-acetyl-L-serine","+","pyrazole","=","3-","(","pyrazol-1-yl",")","-L-alanine","+","acetate","+","H","(","+",")"),4369404). assertion_content_comment('oboGo_BetaRibofuranosylaminobenzene5Phosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","4-aminobenzoate","+","5-phospho-alpha-D-ribose","1-diphosphate","=","4-","(","beta-D-ribofuranosyl",")","aminobenzene","5","'","-phosphate","+","CO2","+","diphosphate","."),4327722). assertion_content_comment('oboGo_BetaSitosteroludpGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","sterol","=","UDP","+","O-glucosyl-beta-sitosterol","."),4283402). assertion_content_comment('oboGo_BetaTubulinbinding',s("Interacting","selectively","and","non-covalently","with","the","microtubule","constituent","protein","beta-tubulin","."),4335774). assertion_content_comment('oboGo_BetaUreidopropionaseactivity',s("Catalysis","of","the","reaction",":","N-carbamoyl-beta-alanine","+","H2O","=","beta-alanine","+","CO2","+","NH3","."),4188710). assertion_content_comment('oboGo_BileAcid7alphaDehydrataseactivity',s("Catalysis","of","the","reaction",":","7alpha",",","12alpha-dihydroxy-3-oxochol-4-en-24-oate","=","12alpha-hydroxy-3-oxochola-4",",","6-dien-24-oate","+","H","(","2",")","O","."),4345286). assertion_content_comment('oboGo_BileAcid7alphaDehydroxylaseactivity',s("Catalysis","of","the","reactions",":","deoxycholate","+","FAD","+","H2O","=","cholate","+","FADH2",",","and","lithocholate","+","FAD","+","H2O","=","chenodeoxycholate","+","FADH2","."),4342336). assertion_content_comment('oboGo_BileAcidCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","deoxycholoyl-CoA","+","H","(","2",")","O","=","CoA","+","deoxycholate","+","H","(","+",")"),4343431). assertion_content_comment('oboGo_BileAcidExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","bile","acid","(","in",")","+","ATP","+","H2O","=","bile","acid","(","out",")","+","ADP","+","phosphate","."),4291892). assertion_content_comment('oboGo_BileSaltsulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","taurolithocholate","=","adenosine","3","'",",","5","'","-bisphosphate","+","taurolithocholate","sulfate","."),4374410). assertion_content_comment('oboGo_BilirubinGlucuronosideglucuronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","bilirubin-glucuronoside","=","bilirubin","+","bilirubin-bisglucuronoside","."),4367568). assertion_content_comment('oboGo_BiochaninAreductaseactivity',s("Catalysis","of","the","reaction",":","dihydrobiochanin","A","+","NADP","(","+",")","=","biochanin","A","+","H","(","+",")","+","NADPH","."),4374389). assertion_content_comment('oboGo_BiosyntheticProcessOfAntibacterialPeptidesActiveAgainstGramNegativebacteria',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","an","antibacterial","peptide","with","activity","against","Gram-negative","bacteria","."),4000793). assertion_content_comment('oboGo_BiosyntheticProcessOfAntibacterialPeptidesActiveAgainstGramPositivebacteria',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","an","antibacterial","peptide","with","activity","against","Gram-positive","bacteria","."),4000868). assertion_content_comment('oboGo_BiotinAcetylCoaCarboxylaseligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","apo-","(","acetyl-CoA",":","carbon-dioxide","ligase","(","ADP","forming",")",")","=","AMP","+","diphosphate","+","(","acetyl-CoA",":","carbon-dioxide","ligase","(","ADP","forming",")",")"),4212576). assertion_content_comment('oboGo_BiotinCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","CoA","=","AMP","+","diphosphate","+","biotinyl-CoA","."),4374437). assertion_content_comment('oboGo_BiotinMethylcrotonoylCoaCarboxylaseligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","apo-","(","3-methylcrotonoyl-CoA",":","carbon-dioxide","ligase","(","ADP-forming",")",")","=","AMP","+","diphosphate","+","(","3-methylcrotonoyl-CoA",":","carbon-dioxide","ligase","(","ADP-forming",")",")"),4212524). assertion_content_comment('oboGo_BiotinMethylmalonylCoaCarboxytransferaseligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","apo-","(","methylmalonyl-CoA",":","pyruvate","carboxytransferase",")","=","AMP","+","diphosphate","+","(","methylmalonyl-CoA",":","pyruvate","carboxytransferase",")"),4212540). assertion_content_comment('oboGo_BiotinPropionylCoaCarboxylaseatpHydrolyzingligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","apo-","(","propanoyl-CoA",":","carbon-dioxide","ligase","(","ADP-forming",")",")","=","AMP","+","diphosphate","+","(","propanoyl-CoA",":","carbon-dioxide","ligase","(","ADP-forming",")",")"),4212447). assertion_content_comment('oboGo_BiotinProteinligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","protein","=","AMP","+","diphosphate","+","biotin-protein","."),4169894). assertion_content_comment('oboGo_BiotinPyruvateCarboxylaseligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","biotin","+","apo-","(","pyruvate-carboxylase",")","=","AMP","+","diphosphate","+","biotin-","(","pyruvate-carboxylase",")"),4169897). assertion_content_comment('oboGo_Biphenyl_23_Diol12_DioxygenaseActivity',s("Catalysis","of","the","reaction",":","biphenyl-2",",","3-diol","+","O2","=","2-hydroxy-6-oxo-6-phenylhexa-2",",","4-dienoate","+","H2O","."),4275412). assertion_content_comment('oboGo_Biphenyl23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","biphenyl","+","NADH","+","H","+","+","O2","=","(","2R",",","3S",")","-3-phenylcyclohexa-3",",","5-diene-1",",","2-diol","+","NAD",".","This","reaction","requires","Fe2","+"),4276767). assertion_content_comment('oboGo_Bis2Ethylhexylphthalateesteraseactivity',s("Catalysis","of","the","reaction",":","bis","(","2-ethylhexyl",")","phthalate","+","H","(","2",")","O","=","2-ethylhexan-1-ol","+","2-ethylhexyl","phthalate","+","H","(","+",")"),4374426). assertion_content_comment('oboGo_Bis4Chlorophenylacetatedecarboxylaseactivity',s("Catalysis","of","the","reaction",":","bis","(","4-chlorophenyl",")","acetate","+","H","+","=","CO2","+","bis","(","4-chlorophenyl",")","methane",".","Bis","(","4-chlorophenyl",")","acetate","is","also","known","as","DDA",";","bis","(","4-chlorophenyl",")","methane","is","also","known","as","DDM","."),4274197). assertion_content_comment('oboGo_Bis5AdenosylHexaphosphataseactivity',s("Catalysis","of","the","reaction",":","P1-P6-bis","(","5","'","-adenosyl",")","hexaphosphate","+","H2O","=","AMP","+","adenosine","5","'","-pentaphosphate","."),4357323). assertion_content_comment('oboGo_Bis5AdenosylPentaphosphataseactivity',s("Catalysis","of","the","reaction",":","P1-P6-bis","(","5","'","-adenosyl",")","pentaphosphate","+","H2O","=","AMP","+","adenosine","5","'","-tetraphosphate","."),4357336). assertion_content_comment('oboGo_Bis5AdenosylTriphosphataseactivity',s("Catalysis","of","the","reaction",":","P","(","1",")",",","P","(","3",")","-bis","(","5","'","-adenosyl",")","triphosphate","+","H","(","2",")","O","=","ADP","+","AMP","+","2","H","(","+",")"),4374499). assertion_content_comment('oboGo_Bis5Nucleosidyloligophosphatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","bis","(","5","'","-nucleosidyl",")","oligophosphate",",","a","compound","formed","of","two","nucleosides","joined","together","through","their","5","'","carbons","by","a","chain","of","phosphate","molecules","."),4294811). assertion_content_comment('oboGo_Bis5Nucleosidyloligophosphatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","bis","(","5","'","-nucleosidyl",")","oligophosphate",",","a","compound","formed","of","two","nucleosides","joined","together","through","their","5","'","carbons","by","a","chain","of","phosphate","molecules","."),4294736). assertion_content_comment('oboGo_Bis5Nucleosidyloligophosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","bis","(","5","'","-nucleosidyl",")","oligophosphate",",","a","compound","formed","of","two","nucleosides","joined","together","through","their","5","'","carbons","by","a","chain","of","phosphate","molecules","."),4294653). assertion_content_comment('oboGo_Bis5NucleosylTetraphosphataseactivity',s("Catalysis","of","the","hydrolysis","of","P","(","1",")",",","P","(","4",")","-bis","(","5","'","-nucleosyl",")","tetraphosphate","into","two","nucleotides","."),4212497). assertion_content_comment('oboGo_Bis5NucleosylTetraphosphataseasymmetricalactivity',s("Catalysis","of","the","reaction",":","P","(","1",")",",","P","(","4",")","-bis","(","5","'","-nucleosyl",")","tetraphosphate","+","H2O","=","NTP","+","NMP",".","Acts","on","bis","(","5","'","-guanosyl",")","-",",","bis","(","5","'","-xanthosyl",")","-",",","bis","(","5","'","-adenosyl",")","-","and","bis","(","5","'","-uridyl",")","-tetraphosphate","."),4212499). assertion_content_comment('oboGo_Bis5NucleosylTetraphosphatasesymmetricalactivity',s("Catalysis","of","the","reaction",":","P","(","1",")",",","P","(","4",")","-bis","(","5","'","-adenosyl",")","tetraphosphate","+","H","(","2",")","O","=","2","ADP","+","2","H","(","+",")"),4250535). assertion_content_comment('oboGo_BisGammaGlutamylcystinereductaseactivity',s("Catalysis","of","the","reaction",":","2","L-gamma-glutamyl-L-cysteine","+","NADP","(","+",")","=","bis-gamma-glutamylcystine","+","H","(","+",")","+","NADPH","."),4365610). assertion_content_comment('oboGo_Bisphosphoglycerate3Phosphataseactivity',s("Catalysis","of","the","reaction",":","2",",","3-diphosphoglycerate","+","H2O","=","2-phosphoglycerate","+","phosphate","."),4357408). assertion_content_comment('oboGo_BlasticidinSdeaminaseactivity',s("Catalysis","of","the","reaction",":","blasticidin","S","+","H2O","=","deaminohydroxyblasticidin","S","+","NH3","."),4374489). assertion_content_comment('oboGo_BLOC_1Complex',s("A","protein","complex","required","for","the","biogenesis","of","specialized","organelles","of","the","endosomal-lysosomal","system",",","such","as","melanosomes","and","platelet","dense","granules",".","Many","of","the","protein","subunits","are","conserved","between","mouse","and","human",";","the","mouse","complex","contains","the","Pallidin",",","Muted",",","Cappuccino",",","Dysbindin",",","Snapin",",","BLOS1",",","BLOS2",",","AND","BLOS3","proteins","."),4319321). assertion_content_comment('oboGo_BLOC_2Complex',s("A","protein","complex","required","for","the","biogenesis","of","specialized","organelles","of","the","endosomal-lysosomal","system",",","such","as","melanosomes","and","platelet","dense","granules",".","The","human","complex","contains","the","Hps3",",","Hps5",",","and","Hps6","proteins",";","the","mouse","complex","contains","ru2","and","ru","."),4319312). assertion_content_comment('oboGo_BLOC_3Complex',s("A","protein","complex","required","for","the","biogenesis","of","specialized","organelles","of","the","endosomal-lysosomal","system",",","such","as","melanosomes","and","platelet","dense","granules",".","The","human","complex","contains","the","Hps1","and","Hps4","proteins","."),4319330). assertion_content_comment('oboGo_Blood_Group_SubstanceEndo_14_Beta_GalactosidaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-galactosidic","linkages","in","blood","group","A","and","B","substances","."),4344727). assertion_content_comment('oboGo_BlueSensitiveopsin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4297297). assertion_content_comment('oboGo_Borneoldehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","+",")","-borneol","+","NAD","(","+",")","=","(","1R",",","4R",")","-camphor","+","H","(","+",")","+","NADH","."),4371751). assertion_content_comment('oboGo_Borneoldehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","-",")","-borneol","+","NAD","(","+",")","=","(","1S",",","4S",")","-camphor","+","H","(","+",")","+","NADH","."),4371708). assertion_content_comment('oboGo_BoxCDSnoRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","a","box","C/D","snoRNA","molecule","."),4362361). assertion_content_comment('oboGo_BoxHACASnoRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","a","box","H/ACA","snoRNA","molecule","."),4362372). assertion_content_comment('oboGo_BrainDerivedneurotrophicfactorbinding',s("Interacting","selectively","and","non-covalently","with","brain-derived","neurotrophic","factor","."),4214132). assertion_content_comment('oboGo_BrainDerivedneurotrophicfactorreceptoractivity',s("Combining","with","brain-derived","neurotrophic","factor",",","to","block","apoptosis","in","neurons","and","promote","nerve","growth",",","or","to","initiate","a","change","in","cell","activity","."),4159765). assertion_content_comment('oboGo_BrainDerivedneurotrophicfactorreceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","brain-derived","neurotrophic","factor","receptor","."),4322165). assertion_content_comment('oboGo_BrainDerivedneurotrophicfactorreceptorsignalingpathway',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","brain-derived","neurotrophic","factor","receptor","binding","to","one","of","its","physiological","ligands","."),4060459). assertion_content_comment('oboGo_BrainReninAngiotensinsystem',s("The","process","in","which","an","angiotensin-mediated","signaling","system","present","in","the","brain","regulates","the","force","with","which","blood","passes","through","the","circulatory","system","."),3999130). assertion_content_comment('oboGo_BrainSpecificangiogenesisinhibitoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4305181). assertion_content_comment('oboGo_Branched_Chain_2_OxoacidDecarboxylaseActivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-methyl-2-oxopentanoate","+","H","(","+",")","=","2-methylbutanal","+","CO","(","2",")"),4370318). assertion_content_comment('oboGo_BranchedChainacylCoasynthetaseadpFormingactivity',s("Catalysis","of","the","reaction",":","ATP","+","2-methylbutanoate","+","CoA","=","ADP","+","orthophosphate","+","2-methylbutanoyl-CoA","."),4326183). assertion_content_comment('oboGo_BranchedChainaliphaticaminoacidtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","branched-chain","aliphatic","amino","acids","from","one","side","of","a","membrane","to","the","other",".","Branched-chain","aliphatic","amino","acids","are","amino","acids","with","a","branched","carbon","skeleton","without","rings","."),4290103). assertion_content_comment('oboGo_BranchedChainaliphaticaminoacidtransport',s("The","directed","movement","of","branched-chain","aliphatic","amino","acids",",","amino","acids","with","branched","carbon","skeleton","without","rings",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4115116). assertion_content_comment('oboGo_Branched_ChainAminoAcid_2_Keto_4_MethylthiobutyrateAminotransferaseActivity',s("Catalysis","of","the","reaction",":","2-keto-4-methylthiobutyrate","+","L-phenylalanine","=","phenylpyruvate","+","L-methionine","."),4327254). assertion_content_comment('oboGo_BranchedChainaminoacid_Sodiumsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","branched-chain","amino","acid","(","out",")","+","cation","(","out",")","=","branched-chain","amino","acid","(","in",")","+","cation","(","in",")"),4290108). assertion_content_comment('oboGo_BranchedChainAminoAcidtransaminaseactivity',s("Catalysis","of","the","reaction",":","a","branched-chain","amino","acid","+","2-oxoglutarate","=","L-glutamate","+","a","2-oxocarboxylate","derived","from","the","branched-chain","amino","acid","."),4191845). assertion_content_comment('oboGo_BranchedChaindodecylbenzenesulfonatemonooxygenaseactivity',s("Catalysis","of","the","reaction",":","branched-chain","dodecylbenzene","sulfonate","+","1/2","O2","+","H","+","=","sulfurous","acid","+","branched-chain","dodecyl-4-hydroxy-benzene","+","sulfite","."),4349049). assertion_content_comment('oboGo_Branched_DextranExo_12_Alpha_GlucosidaseActivity',s("Catalysis","of","the","hydrolysis","of","1",",","2-alpha-D-glucosidic","linkages","at","the","branch","points","of","dextrans","and","related","polysaccharides",",","producing","free","D-glucose","."),4344776). assertion_content_comment('oboGo_BRCA1Acomplex',s("A","protein","complex","that","contains","the","BRCA1-BARD1","heterodimer",",","RAP80/UIMC1",",","BRCC3/BRCC36",",","BRE/BRCC45",",","FAM175A/CCDC98/Abraxas","and","MERIT40/NBA1",",","and","specifically","recognizes","and","binds","K63-linked","polyubiquitin","chains","present","on","histone","H2A","and","H2AX","at","DNA","damage","sites","."),4174402). assertion_content_comment('oboGo_BRCA1Bard1complex',s("A","heterodimeric","complex","comprising","BRCA1","and","BARD1",",","which","possesses","ubiquitin","ligase","activity","and","is","involved","in","genome","maintenance",",","possibly","by","functioning","in","surveillance","for","DNA","damage","."),4321277). assertion_content_comment('oboGo_BRCA1Bcomplex',s("A","protein","complex","that","contains","the","BRCA1-BARD1","heterodimer",",","BACH1","and","TopBP1",",","and","binds","to","DNA","during","S","phase","at","DNA","damage","sites","."),4174460). assertion_content_comment('oboGo_BRCA1Ccomplex',s("A","protein","complex","that","contains","the","BRCA1-BARD1","heterodimer",",","CtIP","and","Mre11/Rad50/NBS1","(","M/R/N",")","complex",",","and","binds","to","DNA","at","DNA","damage","sites",".","BRCA1-C","binding","ta","damaged","DNA","is","required","for","DNA","damage-induced","Chk1","phosphorylation","and","the","G2/M","transition","checkpoint","."),4174450). assertion_content_comment('oboGo_BRCA1Rad51complex',s("A","protein","complex","that","contains","BRCA1","and","Rad","51",",","and","is","involved","in","the","control","of","recombination","and","of","genome","integrity","."),4176286). assertion_content_comment('oboGo_BRCA2Braf35complex',s("A","heterodimeric","complex","of","BRCA2","and","BRAF35","(","BRCA2-associated","factor","35",")","The","BRCA2-BRAF35","complex","is","often","associated","with","condensed","chromatin","during","mitosis","."),4374602). assertion_content_comment('oboGo_BRCA2MageD1complex',s("A","heterodimeric","protein","complex","formed","of","BRCA2","and","MAGE-D1",";","may","mediate","the","synergistic","activities","of","the","two","proteins","in","regulating","cell","growth","."),4340536). assertion_content_comment('oboGo_Butane_14_Diamine_2_OxoglutarateAminotransferaseActivity',s("Catalysis","of","the","reaction",":","putrescine","+","2-oxoglutarate","=","L-glutamate","+","1-pyrroline","+","H2O","."),4347454). assertion_content_comment('oboGo_ButyrateAcetoacetatecoaTransferaseactivity',s("Catalysis","of","the","reaction",":","acetoacetate","+","butanoyl-CoA","=","acetoacetyl-CoA","+","butanoate","."),4368749). assertion_content_comment('oboGo_ButyrateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","an","acid","+","CoA","=","AMP","+","diphosphate","+","an","acyl-CoA","."),4373020). assertion_content_comment('oboGo_ButyrylCoa2CPropionyltransferaseactivity',s("Catalysis","of","the","reaction",":","2-methyl-3-oxohexanoyl-CoA","+","CoA","=","propanoyl-CoA","+","butyryl-CoA","."),4350412). assertion_content_comment('oboGo_ButyrylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","butanoyl-CoA","+","ETF","=","2-butenoyl-CoA","+","reduced","ETF","."),4212350). assertion_content_comment('oboGo_C_19Gibberellin2_Beta_DioxygenaseActivity',s("Catalysis","of","the","reaction",":","a","C-19","gibberellin","+","2-oxoglutarate","+","O2","=","a","C-19","2-beta-hydroxygibberellin","+","succinate","+","CO2",".","C-19","gibberellin","refers","to","a","gibberellin","with","nineteen","carbons","."),4191587). assertion_content_comment('oboGo_C_20Gibberellin2_Beta_DioxygenaseActivity',s("Catalysis","of","the","reaction",":","a","C-20","gibberellin","+","2-oxoglutarate","+","O2","=","a","C-20","2-beta-hydroxygibberellin","+","succinate","+","CO2",".","C-20","gibberellin","refers","to","a","gibberellin","with","twenty","carbons","."),4191571). assertion_content_comment('oboGo_C21Steroidhormonebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","C21-steroid","hormones",",","steroid","compounds","containing","21","carbons","which","function","as","hormones","."),4055976). assertion_content_comment('oboGo_C21Steroidhormonecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","C21-steroid","hormones",",","steroid","compounds","containing","21","carbons","which","function","as","hormones","."),4057391). assertion_content_comment('oboGo_C21Steroidhormonemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","C21-steroid","hormones",",","steroid","compounds","containing","21","carbons","which","function","as","hormones","."),4055971). assertion_content_comment('oboGo_C_22SterolDesaturaseActivity',s("Catalysis","of","the","formation","of","the","C-22","(","23",")","double","bond","in","the","sterol","side","chain",".","An","example","reaction",":","5",",","7",",","24","(","28",")","-ergostatrienol","+","O2","+","NADPH","=","5",",","7",",","22",",","24","(","28",")","-ergostatetraenol","+","2","H2O","+","NADP","+"),4346299). assertion_content_comment('oboGo_C3HC4Typeringfingerdomainbinding',s("Interacting","selectively","and","non-covalently","with","a","C3HC4-type","zinc","finger","domain","of","a","protein",".","The","C3HC4-type","zinc","finger","is","a","variant","of","RING","finger",",","is","a","cysteine-rich","domain","of","40","to","60","residues","that","coordinates","two","zinc","ions",",","and","has","the","consensus","sequence",":","C-X2-C-X","(","9-39",")","-C-X","(","1-3",")","-H-X","(","2-3",")","-C-X2-C-X","(","4-48",")","-C-X2-C",",","where","X","is","any","amino","acid",".","Many","proteins","containing","a","C3HC4-type","RING","finger","play","a","key","role","in","the","ubiquitination","pathway","."),4222294). assertion_content_comment('oboGo_C3HC4TyperingfingerdomainMediatedcomplexassembly',s("A","process","of","protein","complex","assembly","in","which","the","arrangement","and","bonding","together","of","the","set","of","components","that","form","the","protein","complex","is","mediated","by","a","C3HC4-type","RING","finger","domain","interaction","."),4172099). assertion_content_comment('oboGo_C_3SterolDehydrogenaseC_4SterolDecarboxylaseActivity',s("Catalysis","of","the","reaction",":","3-beta-hydroxy-4-beta-methyl-5-alpha-cholesta-8",",","24-dien-4-alpha-carboxylate","+","NAD","(","P",")","+","=","4-alpha-methyl-5-alpha-cholesta-8",",","24-dien-3-one","+","CO2","+","NAD","(","P",")","H","."),4346358). assertion_content_comment('oboGo_C4Dicarboxylatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","C4-dicarboxylate","from","one","side","of","the","membrane","to","the","other","."),4219532). assertion_content_comment('oboGo_C4Dicarboxylatetransport',s("The","directed","movement","of","a","C4-dicarboxylate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","A","C4-dicarboxylate","is","the","anion","of","a","dicarboxylic","acid","that","contains","four","carbon","atoms","."),4164072). assertion_content_comment('oboGo_C_4MethylsterolOxidaseActivity',s("Catalysis","of","the","reaction",":","4",",","4-dimethyl-5-alpha-cholesta-8",",","24-dien-3-beta-ol","+","NAD","(","P",")","H","+","H","+","+","O2","=","4-beta-hydroxymethyl-4-alpha-methyl-5-alpha-cholesta-8",",","24-dien-3-beta-ol","+","NAD","(","P",")","+","+","H2O","."),4182555). assertion_content_comment('oboGo_C_5MethylationOfCytosine',s("The","covalent","transfer","of","a","methyl","group","to","C-5","of","cytosine","in","a","DNA","molecule","."),4148981). assertion_content_comment('oboGo_C_5MethylationOnCytosineInvolvedInChromatinSilencing',s("The","covalent","transfer","of","a","methyl","group","to","C-5","of","cytosine","in","a","DNA","molecule","that","contributes","to","chromatin","silencing","."),4148984). assertion_content_comment('oboGo_C_5SterolDesaturaseActivity',s("Catalysis","of","the","reaction",":","5",",","7",",","24","(","28",")","-ergostatrienol","+","O2","+","NADPH","=","5",",","7",",","22",",","24","(","28",")","-ergostatetraenol","+","2","H2O","+","NADP","+"),4346401). assertion_content_comment('oboGo_C_8SterolIsomeraseActivity',s("Catalysis","of","the","reaction","which","results","in","unsaturation","at","C-7","in","the","B","ring","of","sterols","."),4346390). assertion_content_comment('oboGo_Caa3Typecytochromecoxidase',s("OBSOLETE",".","Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","4","ferrocytochrome","c","+","O2","=","4","ferricytochrome","c","+","2","H2O","."),4259239). assertion_content_comment('oboGo_CAACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CAA","codon","."),4339881). assertion_content_comment('oboGo_CAAXBoxproteinmaturation',s("A","series","of","specific","posttranslational","modifications","to","the","CAAX","box","region","of","CAAX","box","proteins",".","CAAX","box","proteins","are","eukaryotic","proteins","that","contain","a","CAAX","motif","where","the","C","is","a","cysteine",",","the","two","A","residues","are","aliphatic","amino","acids","and","the","X","can","be","one","of","several","amino","acids",".","The","CAAX-box","proteins","undergo","three","sequential",",","enzymatic",",","post-translational","modifications","essential","to","their","targeting",":","First",",","the","proteins","are","prenylated","by","one","of","two","prenyltransferases","called","farnesyltransferase","and","geranylgeranyltransferase-I",".","Prenylation","results","in","the","covalent","attachment","of","either","farnesyl","or","geranylgeranyl","isoprenoid","groups","to","the","cysteine","in","the","CAAX","box","motif",".","Prenylation","is","followed","by","proteolytic","removal","of","the","last","three","amino","acids","of","the","protein","(","AAX",")","Finally",",","the","newly","exposed","carboxylate","group","of","the","isoprenylcysteine","is","methylated","by","an","ER-associated","prenyl-dependent","carboxylmethyltransferase","."),4129675). assertion_content_comment('oboGo_CAAXBoxproteinmodification',s("The","covalent","alteration","of","one","or","more","amino","acid","residues","within","the","CAAX","box","region","of","CAAX","box","proteins","."),4129704). assertion_content_comment('oboGo_CAAXBoxproteinprocessing',s("The","second","process","in","a","series","of","specific","posttranslational","modifications","to","the","CAAX","box","region","of","CAAX","box","proteins",",","in","which","the","last","three","amino","acids","of","the","protein","(","AAX",")","are","removed","by","proteolysis","."),4129714). assertion_content_comment('oboGo_CAAXProteingeranylgeranyltransferaseactivity',s("Catalysis","of","the","reaction",":","geranylgeranyl","diphosphate","+","protein-cysteine","=","S-geranylgeranyl-protein","+","diphosphate",".","This","reaction","is","the","formation","of","a","thioether","linkage","between","the","C-1","atom","of","the","geranylgeranyl","group","and","a","cysteine","residue","fourth","from","the","C-terminus","of","the","protein",".","The","protein","substrates","have","the","C-terminal","sequence","CA1A2X",",","where","the","terminal","residue",",","X",",","is","preferably","leucine","and","A2","should","not","be","aromatic",".","Known","substrates","include","most","g-subunits","of","heterotrimeric","G","proteins","and","Ras-related","GTPases","such","as","members","of","the","Ras","and","Rac/Rho","families","."),4202421). assertion_content_comment('oboGo_CAAXProteingeranylgeranyltransferasecomplex',s("A","heterodimeric","enzyme",",","composed","of","an","alpha","and","a","beta","subunit",".","Participates","in","the","post-translational","C-terminal","modification","of","several","small","GTPases",",","allowing","their","targeting","to","the","membrane","."),4221192). assertion_content_comment('oboGo_CACCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CAC","codon","."),4339915). assertion_content_comment('oboGo_CAcetyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acetyl","group","to","a","carbon","atom","on","the","acceptor","molecule","."),4187138). assertion_content_comment('oboGo_CAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","to","a","carbon","atom","on","the","acceptor","molecule","."),4187081). assertion_content_comment('oboGo_CadmiumExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Cd2","+","(","in",")","=","ADP","+","phosphate","+","Cd2","+","(","out",")"),4252786). assertion_content_comment('oboGo_CadmiumTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Cd","(","cytosol",")","=","ADP","+","phosphate","+","Cd","(","vacuole",")"),4291915). assertion_content_comment('oboGo_CADPRSensitivecalciumReleasechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","channel","that","opens","when","cyclic","adenosine","diphosphate","ribose","(","cADPR",")","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158445). assertion_content_comment('oboGo_CAF_1Complex',s("A","conserved","heterotrimeric","protein","complex","that","promotes","histone","H3","and","H4","deposition","onto","newly","synthesized","DNA","during","replication","or","DNA","repair",";","specifically","facilitates","replication-dependent","nucleosome","assembly","with","the","major","histone","H3","(","H3.1",")","In","many","species","the","CAF-1","subunits","are","designated","p150",",","p60",",","and","p48","."),4347734). assertion_content_comment('oboGo_Caffeate34Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","trans-caffeate","+","O","(","2",")","=","3-","(","2-carboxyethenyl",")","-cis",",","cis-muconate","+","2","H","(","+",")"),4373073). assertion_content_comment('oboGo_CaffeateOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","3",",","4-dihydroxy-trans-cinnamate","=","S-adenosyl-L-homocysteine","+","3-methoxy-4-hydroxy-trans-cinnamate","."),4373039). assertion_content_comment('oboGo_CaffeoylCoaoMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","caffeoyl-CoA","=","S-adenosyl-L-homocysteine","+","feruloyl-CoA","."),4312292). assertion_content_comment('oboGo_CaffeoylCoA_SAdenosylLMethionineoMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","from","S-adenosyl-L-methionine","to","the","oxygen","atom","of","a","caffeoyl","CoA","molecule","."),4182462). assertion_content_comment('oboGo_CAGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CAG","codon","."),4339892). assertion_content_comment('oboGo_CajalRetziuscelldifferentiation',s("The","process","in","which","a","neuroblast","acquires","specialized","structural","and/or","functional","features","of","a","Cajal-Retzius","cell",",","one","of","a","transient","population","of","pioneering","neurons","in","the","cerebral","cortex",".","These","cells","are","slender","bipolar","cells","of","the","developing","marginal","zone",".","One","feature","of","these","cells","in","mammals","is","that","they","express","the","Reelin","gene","."),4047403). assertion_content_comment('oboGo_CAKErcc2complex',s("A","protein","complex","formed","by","the","association","of","the","cyclin-dependent","protein","kinase","activating","kinase","(","CAK",")","holoenzyme","complex","with","ERCC2","."),4174944). assertion_content_comment('oboGo_Calcidiol1Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","calcidiol","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","calcitriol","+","H","(","2",")","O","+","NADP","(","+",")"),4205892). assertion_content_comment('oboGo_CalcineurinNfatsignalingpathway',s("A","series","of","molecular","signals","that","results","in","activation","of","transcription","by","a","member","of","the","NFAT","protein","family","as","a","consequence","of","NFAT","dephosphorylation","by","activated","calcineurin",".","The","signaling","is","generated","by","a","receptor","binding","a","ligand",",","followed","by","activation","of","phospholipase","C","and","the","subsequent","release","of","inositol","trisphosphate",",","which","in","turn","leads","to","an","increase","in","intracellular","calcium","ion","concentration","that","mediates","the","activation","of","calcineurin","."),4132087). assertion_content_comment('oboGo_CalcitoninGeneRelatedpolypeptidereceptoractivity',s("Combining","with","a","calcitonin","gene-related","polypeptide","to","initiate","a","change","in","cell","activity","."),4383970). assertion_content_comment('oboGo_CalciumActivatedpotassiumchannelactivity',s("Catalysis","of","the","calcium","concentration-regulatable","energy-independent","passage","of","potassium","ions","across","a","lipid","bilayer","down","a","concentration","gradient","."),4159419). assertion_content_comment('oboGo_CalciumAndcalmodulinDependentproteinkinasecomplex',s("An","enzyme","complex","which","in","eukaryotes","is","composed","of","four","different","chains",":","alpha",",","beta",",","gamma",",","and","delta",".","The","different","isoforms","assemble","into","homo-","or","heteromultimeric","holoenzymes","composed","of","8","to","12","subunits",".","Catalyzes","the","phosphorylation","of","proteins","to","O-phosphoproteins","."),4221202). assertion_content_comment('oboGo_CalciumAndcalmodulinRegulated35CyclicGmpphosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","guanosine","3","'",",","5","'","-cyclic","phosphate","+","H2O","=","guanosine","5","'","-phosphate",".","The","reaction","is","calmodulin","and","calcium-sensitive","."),4385257). assertion_content_comment('oboGo_CalciumAndcalmodulinResponsiveadenylatecyclaseactivity',s("Catalysis","of","the","reaction",":","ATP","=","3","'",",","5","'","-cyclic","AMP","+","diphosphate",",","stimulated","by","calcium-bound","calmodulin","."),4256325). assertion_content_comment('oboGo_CalciumDependentatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","This","reaction","requires","the","presence","of","calcium","ion","(","Ca2","+",")"),4306992). assertion_content_comment('oboGo_CalciumDependentcelladhesionmoleculeactivity',s("OBSOLETE",".","A","calcium-dependent","cell","adhesion","protein","(","type","I","membrane","protein",")","that","interacts","in","a","homophilic","manner","in","cell-cell","interactions","."),4247348). assertion_content_comment('oboGo_CalciumDependentcellCelladhesion',s("The","attachment","of","one","cell","to","another","cell","via","adhesion","molecules","that","require","the","presence","of","calcium","for","the","interaction","."),4095342). assertion_content_comment('oboGo_CalciumDependentcellMatrixadhesion',s("The","binding","of","a","cell","to","the","extracellular","matrix","via","adhesion","molecules","that","require","the","presence","of","calcium","for","the","interaction","."),4304477). assertion_content_comment('oboGo_CalciumDependentcysteineTypeendopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","nonterminal","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","using","a","cysteine","residue","at","the","enzyme","active","center",",","and","requiring","the","presence","of","calcium","."),4210345). assertion_content_comment('oboGo_CalciumDependentcysteineTypeendopeptidaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","a","calcium-dependent","cysteine-type","endopeptidase",",","any","enzyme","that","hydrolyzes","peptide","bonds","in","polypeptides","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","in","a","calcium-dependent","manner","."),4311254). assertion_content_comment('oboGo_CalciumDependentcytosolicphospholipasea2activity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","phosphatidylcholine","+","H2O","=","1-acylglycerophosphocholine","+","a","fatty","acid","anion","."),4202998). assertion_content_comment('oboGo_CalciumDependentphospholipasea2activity',s("Catalysis","of","the","reaction",":","phosphatidylcholine","+","H2O","=","1-acylglycerophosphocholine","+","a","carboxylate",".","This","reaction","requires","Ca2","+"),4202993). assertion_content_comment('oboGo_CalciumDependentphospholipasecactivity',s("Catalysis","of","the","reaction",":","a","phosphatidylcholine","+","H2O","=","1",",","2-diacylglycerol","+","choline","phosphate",".","This","reaction","requires","Ca2","+"),4266816). assertion_content_comment('oboGo_CalciumDependentphospholipidbinding',s("Interacting","selectively","and","non-covalently","with","phospholipids",",","a","class","of","lipids","containing","phosphoric","acid","as","a","mono-","or","diester",",","in","the","presence","of","calcium","."),4218931). assertion_content_comment('oboGo_CalciumDependentproteinbinding',s("Interacting","selectively","and","non-covalently","with","any","protein","or","protein","complex","(","a","complex","of","two","or","more","proteins","that","may","include","other","nonprotein","molecules",")",",","in","the","presence","of","calcium","."),4334612). assertion_content_comment('oboGo_CalciumDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","a","protein","+","ATP","=","a","phosphoprotein","+","ADP",".","This","reaction","requires","the","presence","of","calcium","."),4202654). assertion_content_comment('oboGo_CalciumDependentproteinkinasecactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","diacylglycerol","and","calcium","."),4202658). assertion_content_comment('oboGo_CalciumDependentproteinkinaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","a","calcium-dependent","protein","kinase","."),4253560). assertion_content_comment('oboGo_CalciumDependentproteinkinaseregulatoractivity',s("Modulates","the","activity","of","a","calcium-dependent","protein","kinase",",","an","enzyme","which","phosphorylates","a","protein","in","a","calcium-dependent","manner","."),4253558). assertion_content_comment('oboGo_CalciumDependentproteinserinethreoninekinaseactivity',s("Catalysis","of","the","reactions",":","ATP","+","a","protein","serine","=","ADP","+","protein","serine","phosphate",";","and","ATP","+","a","protein","threonine","=","ADP","+","protein","threonine","phosphate",".","These","reactions","are","dependent","on","the","presence","of","calcium","ions","."),4202656). assertion_content_comment('oboGo_CalciumDependentproteinserinethreoninephosphataseactivity',s("Catalysis","of","the","reactions",":","protein","serine","phosphate","+","H2O","=","protein","serine","+","phosphate",";","and","protein","threonine","phosphate","+","H2O","=","protein","threonine","+","phosphate",".","These","reactions","require","the","presence","of","calcium","ions","."),4201011). assertion_content_comment('oboGo_CalciumDependentproteinserinethreoninephosphataseregulatoractivity',s("Modulation","of","the","activity","of","the","enzyme","calcium-dependent","protein","serine/threonine","phosphatase","."),4252965). assertion_content_comment('oboGo_CalciumDependentsecretedphospholipasea2activity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","phosphatidylcholine","+","H2O","=","1-acylglycerophosphocholine","+","a","fatty","acid","anion","."),4203093). assertion_content_comment('oboGo_CalciumIncorporationIntoMetalloOxygencluster',s("The","incorporation","of","calcium","into","a","metallo-oxygen","cluster","."),4307579). assertion_content_comment('oboGo_CalciumIncorporationIntoMetalloOxygenclusterviabisLAspartatotrisLGlutamatolHistidinocalciumtetramanganesetetroxide',s("The","incorporation","of","calcium","into","a","4Mn-Ca-4O","complex","by","bis-L-aspartato","tris-L-glutamato","L-histidino","calcium","tetramanganese","tetroxide","as","in","the","photosystem","II","catalytic","site","."),4307581). assertion_content_comment('oboGo_CalciumIndependentcelladhesionmoleculeactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4304491). assertion_content_comment('oboGo_CalciumIndependentcellCelladhesion',s("The","attachment","of","one","cell","to","another","cell","via","adhesion","molecules","that","do","not","require","the","presence","of","calcium","for","the","interaction","."),4119286). assertion_content_comment('oboGo_CalciumIndependentcellMatrixadhesion',s("The","binding","of","a","cell","to","the","extracellular","matrix","via","adhesion","molecules","that","do","not","require","the","presence","of","calcium","for","the","interaction","."),4236219). assertion_content_comment('oboGo_CalciumIndependentcytosolicphospholipasea2activity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","phosphatidylcholine","+","H2O","=","1-acylglycerophosphocholine","+","a","fatty","acid","anion","."),4203020). assertion_content_comment('oboGo_CalciumIndependentphospholipasea2activity',s("Catalysis","of","the","reaction",":","phosphatidylcholine","+","H2O","=","1-acylglycerophosphocholine","+","a","carboxylate",".","This","reaction","does","not","require","Ca2","+"),4203016). assertion_content_comment('oboGo_CalciumIndependentproteinkinasecactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","diacylglycerol","but","not","calcium","."),4202669). assertion_content_comment('oboGo_CalciumInducedcalciumreleaseactivity',s("Release","of","calcium","ions","from","an","intracellular","vesicle","on","induction","by","increased","calcium","concentration","."),4330135). assertion_content_comment('oboGo_CalciumIonDependentexocytosisofneurotransmitter',s("The","release","of","a","neurotransmitter","into","the","synaptic","cleft",",","where","the","release","step","is","dependent","on","the","presence","of","calcium","ions","(","Ca2","+",")","The","neurotransmitter","is","contained","within","a","membrane-bounded","vesicle",",","and","is","released","by","fusion","of","the","vesicle","with","the","presynaptic","plasma","membrane","of","a","nerve","cell","."),4330188). assertion_content_comment('oboGo_CalciumIonDependentexocytosis',s("The","release","of","intracellular","molecules","(","e.g",".","hormones",",","matrix","proteins",")","contained","within","a","membrane-bounded","vesicle","by","fusion","of","the","vesicle","with","the","plasma","membrane","of","a","cell",",","requiring","the","presence","of","calcium","ions","."),3990157). assertion_content_comment('oboGo_CalciumIonIndependentexocytosisofneurotransmitter',s("The","release","of","a","neurotransmitter","into","the","synaptic","cleft",",","where","the","release","step","is","independent","of","the","presence","of","calcium","ions","(","Ca2","+",")","The","neurotransmitter","is","contained","within","a","membrane-bounded","vesicle",",","and","is","released","by","fusion","of","the","vesicle","with","the","presynaptic","plasma","membrane","of","a","nerve","cell","."),4330179). assertion_content_comment('oboGo_CalciumMediatedsignaling',s("A","series","of","molecular","signals","in","which","a","cell","uses","calcium","ions","to","convert","a","signal","into","a","response","."),4047960). assertion_content_comment('oboGo_CalciumMediatedsignalingusingextracellularcalciumsource',s("A","series","of","molecular","signals","in","which","a","cell","uses","calcium","ions","imported","from","an","extracellular","source","to","convert","a","signal","into","a","response","."),4378213). assertion_content_comment('oboGo_CalciumMediatedsignalingusingintracellularcalciumsource',s("A","series","of","molecular","signals","in","which","a","cell","uses","calcium","ions","released","from","an","intracellular","store","to","convert","a","signal","into","a","response","."),4378226). assertion_content_comment('oboGo_CalciumOrCalmodulinMediatedactivationofappressoriumformation',s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","symbiont","calcium","or","calmodulin-mediated","signal","transduction","during","appressorium","formation","on","or","near","its","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153819). assertion_content_comment('oboGo_CalciumOSensingreceptorpathway',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4235493). assertion_content_comment('oboGo_CalciumReleasechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","channel","that","opens","when","a","specific","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158432). assertion_content_comment('oboGo_CalciumTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Ca2","+","(","cis",")","=","ADP","+","phosphate","+","Ca2","+","(","trans",")"),4216754). assertion_content_comment('oboGo_CaldesmonPhosphataseactivity',s("Catalysis","of","the","reaction",":","caldesmon","phosphate","+","H2O","=","caldesmon","+","phosphate","."),4373096). assertion_content_comment('oboGo_CalmodulinDependentcyclicNucleotidephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","nucleoside","3","'",",","5","'","-cyclic","phosphate","+","H2O","=","nucleoside","5","'","-phosphate",";","catalytic","activity","is","regulated","by","calmodulin","."),4212087). assertion_content_comment('oboGo_CalmodulinDependentproteinkinaseactivity',s("Catalysis","of","the","reactions",":","ATP","+","a","protein","serine","=","ADP","+","protein","serine","phosphate",";","and","ATP","+","a","protein","threonine","=","ADP","+","protein","threonine","phosphate",".","These","reactions","require","the","presence","of","calcium-bound","calmodulin","."),4202710). assertion_content_comment('oboGo_CalmodulinDependentproteinphosphataseactivity',s("Catalysis","of","the","reaction",":","protein","serine/threonine","phosphate","+","H2O","=","protein","serine/threonine","+","phosphate",",","dependent","on","the","presence","of","calcium-bound","calmodulin","."),4347659). assertion_content_comment('oboGo_CalmodulinLysinenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","calmodulin","L-lysine","=","S-adenosyl-L-homocysteine","+","calmodulin","N6-methyl-L-lysine","."),4283059). assertion_content_comment('oboGo_CameraTypeeyedevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","camera-type","eye","over","time",",","from","its","formation","to","the","mature","structure",".","The","camera-type","eye","is","an","organ","of","sight","that","receives","light","through","an","aperture","and","focuses","it","through","a","lens",",","projecting","it","on","a","photoreceptor","field","."),3989768). assertion_content_comment('oboGo_CameraTypeeyemorphogenesis',s("The","process","in","which","the","anatomical","structures","of","the","eye","are","generated","and","organized",".","The","camera-type","eye","is","an","organ","of","sight","that","receives","light","through","an","aperture","and","focuses","it","through","a","lens",",","projecting","it","on","a","photoreceptor","field","."),3989801). assertion_content_comment('oboGo_CameraTypeeyephotoreceptorcelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","cell","acquires","the","specialized","features","of","a","photoreceptor","cell","in","a","camera-type","eye","."),4033544). assertion_content_comment('oboGo_CameraTypeeyephotoreceptorcellfatecommitment',s("The","process","in","which","the","developmental","fate","of","a","cell","becomes","restricted","such","that","it","will","develop","into","a","photoreceptor","cell","in","a","camera-type","eye","."),4033546). assertion_content_comment('oboGo_CAMPDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","presence","of","cAMP","."),4202585). assertion_content_comment('oboGo_CAMPDependentproteinkinasecomplex',s("An","enzyme","complex",",","composed","of","regulatory","and","catalytic","subunits",",","that","catalyzes","protein","phosphorylation",".","Inactive","forms","of","the","enzyme","have","two","regulatory","chains","and","two","catalytic","chains",";","activation","by","cAMP","produces","two","active","catalytic","monomers","and","a","regulatory","dimer","."),4221177). assertion_content_comment('oboGo_CAMPDependentproteinkinaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","a","cAMP-dependent","protein","kinase","."),4200331). assertion_content_comment('oboGo_CAMPDependentproteinkinaseregulatoractivity',s("Modulation","of","the","activity","of","the","enzyme","cAMP-dependent","protein","kinase","."),4253153). assertion_content_comment('oboGo_Camphor12Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","+",")","-bornane-2",",","5-dione","+","reduced","rubredoxin","+","O2","=","5-oxo-1",",","2-campholide","+","oxidized","rubredoxin","+","H2O","."),4276778). assertion_content_comment('oboGo_Camphor5Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","+",")","-camphor","+","putidaredoxin","+","O2","=","(","+",")","-exo-5-hydroxycamphor","+","oxidized","putidaredoxin","+","H2O","."),4276717). assertion_content_comment('oboGo_Camphorbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","(","+",")","-camphor",",","a","bicyclic","monoterpene","ketone","."),4354338). assertion_content_comment('oboGo_Camphorcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","(","+",")","-camphor",",","a","bicyclic","monoterpene","ketone","."),4239777). assertion_content_comment('oboGo_Camphormetabolicprocess',s("The","chemical","reactions","and","pathways","involving","(","+",")","-camphor",",","a","bicyclic","monoterpene","ketone","which","is","one","of","the","major","components","in","the","leaves","of","common","sage",".","Camphor","exists","in","two","enantiomers",",","but","the","(","+",")","-isomer","is","more","widely","distributed","."),4239758). assertion_content_comment('oboGo_CAMPMediatedactivationofappressoriumformation',s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","symbiont","cAMP","mediated","signal","transduction","during","appressorium","formation","on","or","near","its","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153841). assertion_content_comment('oboGo_CAMPMediatedsignaling',s("A","series","of","molecular","signals","in","which","a","cell","uses","cyclic","AMP","to","convert","an","extracellular","signal","into","a","response","."),4027444). assertion_content_comment('oboGo_CanonicalWntReceptorSignalingPathwayInvolvedInPositiveRegulationOfCellCelladhesion',s("The","series","of","molecular","signals","initiated","by","binding","of","a","Wnt","protein","to","a","frizzled","family","receptor","on","the","surface","of","the","target","cell",",","followed","by","propagation","of","the","signal","via","beta-catenin",",","and","ending","with","a","change","in","transcription","of","target","genes","involved","in","the","positive","regulation","of","cell","to","cell","adhesion","."),4096854). assertion_content_comment('oboGo_Canthaxanthin3Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","canthaxanthin","+","a","reduced","electron","acceptor","+","oxygen","=","adonirubin","+","an","oxidized","electron","acceptor","+","H2O","."),4191103). assertion_content_comment('oboGo_CAPGlydomainbinding',s("Interacting","selectively","and","non-covalently","with","a","CAP-Gly","domain","of","a","protein",".","The","CAP_Gly","domain","is","a","conserved",",","glycine-rich","domain","of","about","42","residues","found","in","some","cytoskeleton-associated","proteins",",","and","features","a","novel","protein","fold","containing","three","beta-sheets","."),4169353). assertion_content_comment('oboGo_Capsular_PolysaccharideEndo_13_Alpha_GalactosidaseActivity',s("Catalysis","of","the","random","hydrolysis","of","1",",","3-alpha-D-galactosidic","linkages","in","Aerobacter","aerogenes","capsular","polysaccharide","."),4344612). assertion_content_comment('oboGo_CapsularPolysaccharideTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","capsular","polysaccharide","(","in",")","=","ADP","+","phosphate","+","capsular","polysaccharide","(","out",")"),4291954). assertion_content_comment('oboGo_CapsulePolyGammaGlutamatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","poly-gamma-glutamate",",","a","polymer","of","D-","and/or","L-glutamic","acid","residues","linked","by","gamma-peptidyl","bonds",",","that","forms","all","or","part","of","a","bacterial","capsule","."),4174907). assertion_content_comment('oboGo_CarbamoylPhosphateAdptransphosphorylation',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4229274). assertion_content_comment('oboGo_CarbamoylPhosphatesynthaseactivity',s("Catalysis","of","a","reaction","that","results","in","the","formation","of","carbamoyl","phosphate","."),4212372). assertion_content_comment('oboGo_CarbamoylPhosphatesynthaseammoniaactivity',s("Catalysis","of","the","reaction",":","2","ATP","+","CO","(","2",")","+","H","(","2",")","O","+","NH","(","4",")","(","+",")","=","2","ADP","+","carbamoyl","phosphate","+","5","H","(","+",")","+","phosphate","."),4212383). assertion_content_comment('oboGo_CarbamoylPhosphatesynthasecomplex',s("A","protein","complex","that","catalyzes","the","formation","of","carbamoyl","phosphate",";","comprises","a","small","subunit","that","binds","and","cleaves","glutamine",",","and","a","large","subunit","that","accepts","the","ammonia","group","cleaved","from","glutamine",",","binds","all","of","the","remaining","substrates","and","effectors",",","and","carries","out","all","of","the","other","catalytic","events","."),4221163). assertion_content_comment('oboGo_CarbamoylPhosphatesynthaseglutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","2","ATP","+","L-glutamine","+","CO2","+","H2O","=","2","ADP","+","phosphate","+","glutamate","+","carbamoyl","phosphate","."),4212406). assertion_content_comment('oboGo_CarbamoylSerineammoniaLyaseactivity',s("Catalysis","of","the","reaction",":","O-carbamoyl-L-serine","+","H","(","2",")","O","+","H","(","+",")","=","CO","(","2",")","+","2","NH","(","4",")","(","+",")","+","pyruvate","."),4373108). assertion_content_comment('oboGo_Carbazole19aDioxygenaseactivity',s("Catalysis","of","the","reaction",":","carbazole","+","NADH","+","O2","+","H","+","=","NAD","+","+","2","'","-aminobiphenyl-2",",","3-diol","."),4278855). assertion_content_comment('oboGo_CarbohydrateExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","carbohydrate","(","in",")","=","ADP","+","phosphate","+","carbohydrate","(","out",")"),4318647). assertion_content_comment('oboGo_CarbohydrateImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","carbohydrate","(","out",")","=","ADP","+","phosphate","+","carbohydrate","(","in",")"),4289464). assertion_content_comment('oboGo_CarbohydrateTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",",","to","directly","drive","the","transport","of","carbohydrates","across","a","membrane","."),4289461). assertion_content_comment('oboGo_CarbonCarbonlyaseactivity',s("Catalysis","of","the","cleavage","of","C-C","bonds","by","other","means","than","by","hydrolysis","or","oxidation",",","or","conversely","adding","a","group","to","a","double","bond","."),4073958). assertion_content_comment('oboGo_CarbonFixationBy3Hydroxypropionatecycle',s("An","autotrophic","carbon","dioxide","fixation","pathway","by","which","two","molecules","of","carbon","dioxide","are","fixed","to","form","glyoxylate",".","Acetyl","coenzyme","A","(","acetyl-CoA",")","is","assumed","to","be","converted","to","malate",",","and","two","CO2","molecules","are","thereby","fixed",".","Malyl-CoA","is","thought","to","be","cleaved","to","acetyl-CoA",",","the","starting","molecule",",","and","glyoxylate",",","the","carbon","fixation","product","."),4324967). assertion_content_comment('oboGo_CarbonFixationByAcetylCoapathway',s("A","pathway","of","carbon","dioxide","fixation","in","which","one","molecule","of","acetyl-CoA","is","completely","synthesized","from","two","molecules","of","carbon","dioxide","(","CO2",")"),4308145). assertion_content_comment('oboGo_CarbonHalidelyaseactivity',s("Catalysis","of","the","breakage","of","a","bond","between","carbon","and","any","halogen","atom","."),4237473). assertion_content_comment('oboGo_CarbonMonoxidedehydrogenaseacceptoractivity',s("Catalysis","of","the","reaction",":","CO","+","H2O","+","acceptor","=","CO2","+","reduced","acceptor","."),4277359). assertion_content_comment('oboGo_CarbonMonoxidedehydrogenaseferredoxinactivity',s("Catalysis","of","the","reaction",":","CO","+","H2O","+","oxidized","ferredoxin","=","CO2","+","reduced","ferredoxin","."),4326775). assertion_content_comment('oboGo_CarbonMonoxideoxygenaseactivity',s("Catalysis","of","the","reaction",":","CO","+","H2O","+","ferrocytochrome","b-561","=","CO2","+","2","H","+","+","2","ferricytochrome","b-561","."),4250577). assertion_content_comment('oboGo_CarbonNitrogenligaseactivitywithglutamineasamidoNDonor',s("Catalysis","of","the","transfer","of","the","amide","nitrogen","of","glutamine","to","a","variety","of","substrates",".","GATases","catalyze","two","separate","reactions","at","two","active","sites",",","which","are","located","either","on","a","single","polypeptide","chain","or","on","different","subunits",".","In","the","glutaminase","reaction",",","glutamine","is","hydrolyzed","to","glutamate","and","ammonia",",","which","is","added","to","an","acceptor","substrate","in","the","synthase","reaction","."),4183053). assertion_content_comment('oboGo_CarbonNitrogenlyaseactivity',s("Catalysis","of","the","release","of","ammonia","or","one","of","its","derivatives",",","with","the","formation","of","a","double","bond","or","ring",".","Enzymes","with","this","activity","may","catalyze","the","actual","elimination","of","the","ammonia",",","amine","or","amide",",","e.g",".","CH-CH","(","-NH-R",")","=","C","=","CH-","+","NH2-R",".","Others",",","however",",","catalyze","elimination","of","another","component",",","e.g",".","water",",","which","is","followed","by","spontaneous","reactions","that","lead","to","breakage","of","the","C-N","bond",",","e.g",".","L-serine","ammonia-lyase","(","EC",":","4.3.1.17",")",",","so","that","the","overall","reaction","is","C","(","-OH",")","-CH","(","-NH2",")","=","CH2-CO-","+","NH3",",","i.e",".","an","elimination","with","rearrangement",".","The","sub-subclasses","of","EC",":","4.3","are","the","ammonia-lyases","(","EC",":","4.3.1",")",",","lyases","acting","on","amides",",","amidines",",","etc",".","(","EC",":","4.3.2",")",",","the","amine-lyases","(","EC",":","4.3.3",")",",","and","other","carbon-nitrogen","lyases","(","EC",":","4.3.99",")"),4177030). assertion_content_comment('oboGo_CarbonOxygenlyaseactivityactingonphosphates',s("Catalysis","of","the","cleavage","of","a","carbon-oxygen","bond","by","elimination","of","a","phosphate","."),4182100). assertion_content_comment('oboGo_CarbonOxygenlyaseactivityactingonpolysaccharides',s("Catalysis","of","the","cleavage","of","a","carbon-oxygen","bond","by","the","elimination","of","an","alcohol","from","a","polysaccharide","."),4296783). assertion_content_comment('oboGo_CarbonOxygenlyaseactivity',s("Catalysis","of","the","breakage","of","a","carbon-oxygen","bond","."),4173780). assertion_content_comment('oboGo_CarbonSulfurlyaseactivity',s("Catalysis","of","the","elimination","of","hydrogen","sulfide","or","substituted","H2S","."),4181066). assertion_content_comment('oboGo_CarbonylCyanideMChlorophenylhydrazonenalidixicacidorganomercurials_Hydrogenantiporteractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4293040). assertion_content_comment('oboGo_CarbonylCyanideMChlorophenylhydrazonetransporteractivity',s("Enables","the","directed","movement","of","carbonyl","cyanide","m-chlorophenylhydrazone","into",",","out","of","or","within","a","cell",",","or","between","cells",".","Carbonyl","cyanide","m-chlorophenylhydrazone","is","a","proton","ionophore",",","commonly","used","as","an","uncoupling","agent","and","inhibitor","of","photosynthesis","because","of","its","effects","on","mitochondrial","and","chloroplast","membranes","."),4293035). assertion_content_comment('oboGo_CarbonylCyanideMChlorophenylhydrazonetransport',s("The","directed","movement","of","carbonyl","cyanide","m-chlorophenylhydrazone","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Carbonyl","cyanide","m-chlorophenylhydrazone","is","a","proton","ionophore",",","commonly","used","as","an","uncoupling","agent","and","inhibitor","of","photosynthesis","because","of","its","effects","on","mitochondrial","and","chloroplast","membranes","."),4294415). assertion_content_comment('oboGo_CarboxyCiscisMuconatecyclaseactivity',s("Catalysis","of","the","reaction",":","3-carboxy-2",",","5-dihydro-5-oxofuran-2-acetate","=","3-carboxy-cis",",","cis-muconate","."),4373084). assertion_content_comment('oboGo_CarboxyethylArginineBetaLactamSynthaseactivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-","(","2-carboxyethyl",")","-L-arginine","+","ATP","=","AMP","+","deoxyamidinoproclavaminate","+","diphosphate","+","2","H","(","+",")"),4361068). assertion_content_comment('oboGo_CarboxylicAcidTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","carboxylic","acid","(","out/in",")","=","ADP","+","phosphate","+","carboxylic","acid","(","in/out",")"),4337795). assertion_content_comment('oboGo_CarboxylOMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","to","the","carboxyl","group","of","an","acceptor","molecule","to","form","a","methyl","ester","."),4183606). assertion_content_comment('oboGo_CarboxylOrcarbamoyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","carboxyl-","or","carbamoyl","group","from","one","compound","(","donor",")","to","another","(","acceptor",")"),4204117). assertion_content_comment('oboGo_CarboxyLyaseactivity',s("Catalysis","of","the","nonhydrolytic","addition","or","removal","of","a","carboxyl","group","to","or","from","a","compound","."),4183584). assertion_content_comment('oboGo_CarboxyTerminaldomainproteinkinasecomplex',s("A","protein","complex","that","phosphorylates","amino","acid","residues","of","RNA","polymerase","II","C-terminal","domain","repeats",";","phosphorylation","occurs","mainly","on","Ser2","and","Ser5","."),3976570). assertion_content_comment('oboGo_CarboxyvinylCarboxyphosphonatephosphorylmutaseactivity',s("Catalysis","of","the","reaction",":","1-carboxyvinyl","carboxyphosphonate","=","3-","(","hydrohydroxyphosphoryl",")","pyruvate","+","CO2","."),4250650). assertion_content_comment('oboGo_CardioblastAnteriorLateralmigration',s("The","orderly","movement","of","a","cardioblast","toward","the","head","and","laterally","to","form","the","heart","field",".","A","cardioblast","is","a","cardiac","precursor","cell",".","It","is","a","cell","that","has","been","committed","to","a","cardiac","fate",",","but","will","undergo","more","cell","division","rather","than","terminally","differentiating","."),4194321). assertion_content_comment('oboGo_CargoLoadingIntoClathrin_CoatedVesicleAP_1_Mediated',s("Formation","of","a","protein","complex","between","proteins","of","the","AP-1","adaptor","complex","and","proteins","that","are","going","to","be","transported","by","a","clathrin-coated","vesicle",".","The","AP-1","adaptor","protein","complex","is","a","component","of","the","cytoplasmic","coat","found","on","clathrin-coated","vesicles",",","and","binds","to","sorting","signals","of","cargo","to","facilitate","their","trafficking","."),4380195). assertion_content_comment('oboGo_CargoLoadingIntoClathrin_CoatedVesicleAP_3_Mediated',s("Formation","of","a","protein","complex","between","proteins","of","the","AP-3","adaptor","complex","and","proteins","that","are","going","to","be","transported","by","a","clathrin-coated","vesicle",".","In","some","cases",",","The","AP-3","complex","is","a","heterotetrameric","AP-type","membrane","coat","adaptor","complex","that",",","in","some","organisms",",","links","clathrin","to","the","membrane","surface","of","a","vesicle","."),4380243). assertion_content_comment('oboGo_CargoLoadingIntoClathrinCoatedvesicle',s("Formation","of","a","protein","complex","between","the","cytoplasmic","coat","proteins","on","clathrin-coated","vesicles","and","proteins","that","are","going","to","be","transported","by","a","vesicle","."),4380186). assertion_content_comment('oboGo_CargoLoadingIntoCOPIICoatedvesicle',s("The","formation","of","a","protein","complex","between","the","COPII","coat","proteins","and","proteins","that","are","going","to","be","transported","by","the","COPII","vesicle","to","the","Golgi","."),4148920). assertion_content_comment('oboGo_Carnitine3Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","carnitine","+","NAD","(","+",")","=","3-dehydrocarnitine","+","H","(","+",")","+","NADH","."),4373613). assertion_content_comment('oboGo_CarnitineCoaligaseactivity',s("Catalysis","of","the","reaction",":","D-carnitine","+","CoA","+","ATP","=","AMP","+","diphosphate","+","D-carnitinyl-CoA","."),4250212). assertion_content_comment('oboGo_CarnitineMetabolicProcessCoALinked',s("The","chemical","reactions","and","pathways","involving","carnitine",",","where","metabolism","is","linked","to","CoA","."),4237972). assertion_content_comment('oboGo_CarnitineOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","carnitine","=","(","R",")","-O-acetylcarnitine","+","CoA","."),4212255). assertion_content_comment('oboGo_CarnitineOAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","to","an","oxygen","atom","on","the","carnitine","molecule","."),4212188). assertion_content_comment('oboGo_CarnitineOOctanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-carnitine","+","octanoyl-CoA","=","(","S",")","-octanoylcarnitine","+","CoA","."),4254021). assertion_content_comment('oboGo_CarnitineOPalmitoyltransferaseactivity',s("Catalysis","of","the","reaction",":","palmitoyl-CoA","+","L-carnitine","=","CoA","+","L-palmitoylcarnitine","."),4212201). assertion_content_comment('oboGo_CarnosineNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","carnosine","=","S-adenosyl-L-homocysteine","+","anserine","+","H","(","+",")"),4308862). assertion_content_comment('oboGo_Carotene78Desaturaseactivity',s("Catalysis","of","the","reaction",":","neurosporene","+","donor-H2","+","O2","=","lycopene","+","acceptor","+","2","H2O","."),4301312). assertion_content_comment('oboGo_CaroteneBetaRinghydroxylaseactivity',s("Catalysis","of","C3-hydroxylation","of","the","beta-ring","of","various","carotenes","."),4335128). assertion_content_comment('oboGo_Caspase_10Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209078). assertion_content_comment('oboGo_Caspase_1Activity',s("OBSOLETE",".","Catalysis","of","the","release","of","interleukin","1-beta","by","specific","cleavage","of","Asp116-Ala117","and","Asp27-Gly28","bonds","in","precursor",".","Enzymes","with","this","function","can","also","hydrolyze","the","terminal","bond","in","the","small-molecule","substrate",",","Ac-Tyr-Val-Ala-Asp-NHMec","."),4209134). assertion_content_comment('oboGo_Caspase_2Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209123). assertion_content_comment('oboGo_Caspase_3Activity',s("OBSOLETE",".","Catalysis","of","the","cleavage","at","the","terminal","bond","of","the","motif",":","Asp-Xaa-Xaa-Asp-Xaa",".","Enzymes","with","this","function","are","members","of","the","peptidase","family","C14","and","they","appear","to","function","in","the","inactivation","of","proteins","involved","in","cellular","repair","and","homeostasis","during","the","effector","stage","of","apoptosis","."),4209100). assertion_content_comment('oboGo_Caspase_4Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209157). assertion_content_comment('oboGo_Caspase_5Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209146). assertion_content_comment('oboGo_Caspase_6Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209344). assertion_content_comment('oboGo_Caspase_7Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209179). assertion_content_comment('oboGo_Caspase_8Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209089). assertion_content_comment('oboGo_Caspase_9Activity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209168). assertion_content_comment('oboGo_Catechol12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","catechol","+","O2","=","cis",",","cis-muconate","."),4278738). assertion_content_comment('oboGo_Catechol23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","catechol","+","O2","=","2-hydroxymuconate","semialdehyde","."),4278757). assertion_content_comment('oboGo_CatecholCatabolicProcessMetaCleavage',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","catechol","via","the","meta-cleavage","pathway",",","in","which","the","catechol","aromatic","ring","is","broken","between","a","hydroxylated","carbon","atom","and","an","adjacent","unsubstituted","carbon","atom","."),4243752). assertion_content_comment('oboGo_CatecholCatabolicProcessOrthoCleavage',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","catechol","via","the","ortho-cleavage","pathway",",","in","which","the","catechol","aromatic","ring","is","broken","between","the","two","carbon","atoms","bearing","hydroxyl","groups","."),4243819). assertion_content_comment('oboGo_CatecholOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","a","catechol","=","S-adenosyl-L-homocysteine","+","a","guaiacol","."),4303842). assertion_content_comment('oboGo_CateninTcf7l2complex',s("A","protein","complex","that","contains","a","catenin","and","TCF7L2","(","TCF4",")",",","binds","to","the","TCF","DNA","motif","within","a","promoter","element",",","and","is","involved","in","the","regulation","of","WNT","target","gene","transcription","."),4172368). assertion_content_comment('oboGo_CationTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","cation","(","out",")","=","ADP","+","phosphate","+","cation","(","in",")"),4185952). assertion_content_comment('oboGo_CAUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CAU","codon","."),4339903). assertion_content_comment('oboGo_CaveolinMediatedendocytosis',s("An","endocytosis","process","that","begins","when","material","is","taken","up","into","plasma","membrane","caveolae",",","which","then","pinch","off","to","form","endocytic","caveolar","carriers","."),4157670). assertion_content_comment('oboGo_Cbb3Typecytochromecoxidase',s("OBSOLETE",".","Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","4","ferrocytochrome","c","+","O2","=","4","ferricytochrome","c","+","2","H2O","."),4259206). assertion_content_comment('oboGo_CCAATBindingfactorcomplex',s("A","heteromeric","transcription","factor","complex","that","binds","to","the","CCAAT-box","upstream","of","promoters",";","in","Saccharomyces","it","activates","the","transcription","of","genes","in","response","to","growth","in","a","nonfermentable","carbon","source",";","consists","of","four","known","subunits",":","HAP2",",","HAP3",",","HAP4","and","HAP5","."),4305966). assertion_content_comment('oboGo_CCACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CCA","codon","."),4340228). assertion_content_comment('oboGo_CCCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CCC","codon","."),4340194). assertion_content_comment('oboGo_CCchemokinebinding',s("Interacting","selectively","and","non-covalently","with","a","C-C","chemokine",";","C-C","chemokines","do","not","have","an","amino","acid","between","the","first","two","cysteines","of","the","characteristic","four-cysteine","motif","."),4169238). assertion_content_comment('oboGo_CCchemokinereceptoractivity',s("Combining","with","a","C-C","chemokine","to","initiate","a","change","in","cell","activity",".","C-C","chemokines","do","not","have","an","amino","acid","between","the","first","two","cysteines","of","the","characteristic","four-cysteine","motif","."),4304971). assertion_content_comment('oboGo_CCGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CCG","codon","."),4340217). assertion_content_comment('oboGo_CCPreferringendodeoxyribonucleaseactivity',s("Catalysis","of","the","endonucleolytic","cleavage","to","give","5","'","-phosphooligonucleotide","end-products",",","with","a","preference","for","cleavage","within","the","sequence","CC","."),4344055). assertion_content_comment('oboGo_CCR4Notcomplex',s("A","large","multimeric","transcription","factor","complex","that","can","regulate","transcription","positively","or","negatively",";","consists","of","a","core","complex","plus","additional","proteins",";","may","interact","with","other","proteins","to","control","initiation","of","transcription",".","In","Saccharomyces","the","core","complex","comprises","Ccr4p",",","Caf1p",",","Not1p",",","Not2p",",","Not3p",",","Not4p",",","and","Not5p",";","Caf4p",",","Caf16p",",","and","several","less","well","characterized","proteins","."),4052687). assertion_content_comment('oboGo_CCR4Notcorecomplex',s("The","core","of","the","CCR4-NOT","transcription","factor","complex",".","In","Saccharomyces","the","CCR4-NOT","core","complex","comprises","Ccr4p",",","Caf1p",",","Not1p",",","Not2p",",","Not3p",",","Not4p",",","and","Not5p","."),4052698). assertion_content_comment('oboGo_CCUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CCU","codon","."),4340205). assertion_content_comment('oboGo_CD19VavPik3r1complex',s("A","protein","complex","that","contains","the","cell","surface","signaling","molecule","CD19",",","the","Ras","guanine","nucleotide","exchange","factor","Vav",",","and","the","regulatory","subunit","alpha","of","phosphatidylinositol","3-kinase","(","PI3K",")"),4180470). assertion_content_comment('oboGo_CD20LckFyncomplex',s("A","protein","complex","that","contains","the","cell-surface","protein","CD20","and","the","Src","family","tyrosine","kinases","Lck","and","Fyn","."),4173247). assertion_content_comment('oboGo_CD20LckLynFyncomplex',s("A","protein","complex","that","contains","the","cell-surface","protein","CD20","and","the","Src","family","tyrosine","kinases","Lck",",","Lyn","and","Fyn","."),4173257). assertion_content_comment('oboGo_CD4PositivealphaBetaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD4-positive",",","alpha-beta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4380453). assertion_content_comment('oboGo_CD4PositivealphaBetatcellactivation',s("The","change","in","morphology","and","behavior","of","a","CD4-positive",",","alpha-beta","T","cell","resulting","from","exposure","to","a","mitogen",",","cytokine",",","chemokine",",","cellular","ligand",",","or","an","antigen","for","which","it","is","specific","."),3992525). assertion_content_comment('oboGo_CD4Positivealphabetatcellcostimulation',s("The","process","of","providing",",","via","surface-bound","receptor-ligand","pairs",",","a","second",",","antigen-independent",",","signal","in","addition","to","that","provided","by","the","T","cell","receptor","to","augment","CD4-positive",",","alpha","beta","T","cell","activation","."),4381103). assertion_content_comment('oboGo_CD4PositivealphaBetatcellcytokineproduction',s("Any","process","that","contributes","to","cytokine","production","by","a","CD4-positive",",","alpha-beta","T","cell","."),4082429). assertion_content_comment('oboGo_CD4PositivealphaBetatcelldifferentiationinvolvedinimmuneresponse',s("The","process","in","which","an","antigenically","naive","CD4-positive",",","alpha-beta","T","cell","acquires","the","specialized","features","of","an","effector",",","regulatory",",","or","memory","T","cell","as","part","of","an","immune","response",".","Effector","T","cells","include","cells","which","provide","T","cell","help","or","exhibit","cytotoxicity","towards","other","cells","."),3992535). assertion_content_comment('oboGo_CD4PositivealphaBetatcelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","T","cell","acquires","specialized","features","of","a","mature","CD4-positive",",","alpha-beta","T","cell","."),3992528). assertion_content_comment('oboGo_CD4PositivealphaBetatcelllineagecommitment',s("The","process","in","which","an","immature","T","cell","becomes","committed","to","becoming","a","CD4-positive",",","alpha-beta","T","cell","."),4095795). assertion_content_comment('oboGo_CD4PositivealphaBetatcellproliferation',s("The","expansion","of","a","CD4-positive",",","alpha-beta","T","cell","population","by","cell","division","."),4144372). assertion_content_comment('oboGo_CD4Positivecd25PositivealphaBetaregulatorytcelldifferentiationinvolvedinimmuneresponse',s("The","process","in","which","an","antigenically","naive","CD4-positive",",","alpha-beta","T","cell","acquires","the","specialized","features","of","a","CD4-positive",",","CD25-positive",",","alpha-beta","regulatory","T","cell","as","part","of","an","immune","response","."),4069520). assertion_content_comment('oboGo_CD4Positivecd25PositivealphaBetaregulatorytcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD4-positive",",","CD25-positive",",","alpha-beta","regulatory","T","cell","."),3994175). assertion_content_comment('oboGo_CD4Positivecd25PositivealphaBetaregulatorytcelllineagecommitment',s("The","process","in","which","a","CD4-positive",",","alpha-beta","T","cell","becomes","committed","to","becoming","a","CD4-positive",",","CD25-positive",",","alpha-beta","regulatory","T","cell","."),3994189). assertion_content_comment('oboGo_CD4PositivegammaDeltaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD4-positive",",","gamma-delta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4380539). assertion_content_comment('oboGo_CD4Positiveorcd8PositivealphaBetatcelllineagecommitment',s("The","process","in","which","an","immature","T","cell","commits","to","CD4-positive","T","cell","lineage","or","the","CD8-positive","lineage","of","alpha-beta","T","cells","."),4095471). assertion_content_comment('oboGo_CD8PositivealphaBetacytotoxictcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD8-positive",",","alpha-beta","cytotoxic","T","cell","."),4380554). assertion_content_comment('oboGo_CD8PositivealphaBetacytotoxictcellextravasation',s("The","migration","of","a","CD8-positive",",","alpha-beta","cytotoxic","T","cell","from","the","blood","vessels","into","the","surrounding","tissue","."),4142259). assertion_content_comment('oboGo_CD8PositivealphaBetaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD8-positive",",","alpha-beta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4380438). assertion_content_comment('oboGo_CD8PositivealphaBetaregulatorytcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD8-positive",",","alpha-beta","regulatory","T","cell","."),4380525). assertion_content_comment('oboGo_CD8PositivealphaBetatcelldifferentiationinvolvedinimmuneresponse',s("The","process","in","which","an","antigenically","naive","CD8-positive",",","alpha-beta","T","cell","acquires","the","specialized","features","of","an","effector",",","regulatory",",","or","memory","T","cell","as","part","of","an","immune","response",".","Effector","T","cells","include","cells","which","provide","T","cell","help","or","exhibit","cytotoxicity","towards","other","cells","."),4380405). assertion_content_comment('oboGo_CD8PositivealphaBetatcelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","T","cell","acquires","specialized","features","of","a","mature","CD8-positive",",","alpha-beta","T","cell","."),4095808). assertion_content_comment('oboGo_CD8PositivealphaBetatcellextravasation',s("The","migration","of","a","CD8-positive",",","alpha-beta","T","cell","from","the","blood","vessels","into","the","surrounding","tissue","."),4142257). assertion_content_comment('oboGo_CD8PositivealphaBetatcelllineagecommitment',s("The","process","in","which","an","immature","T","cell","becomes","committed","to","becoming","a","CD8-positive",",","alpha-beta","T","cell","."),4095822). assertion_content_comment('oboGo_CD8PositivealphaBetatcellproliferation',s("The","expansion","of","a","CD8-positive",",","alpha-beta","T","cell","population","by","cell","division","."),4144212). assertion_content_comment('oboGo_CD8PositivegammaDeltaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","CD8-positive",",","gamma-delta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4380390). assertion_content_comment('oboGo_CD95DeathInducingsignalingcomplex',s("A","protein","complex","formed","upon","binding","of","Fas/CD95/APO-1","to","its","ligand",".","The","complex","includes","FADD/Mort1",",","procaspase-8/10","and","c-FLIP","in","addition","to","the","ligand-bound","receptor","."),4320110). assertion_content_comment('oboGo_Cdc48pNpl4pUfd1paaaatpasecomplex',s("A","multiprotein","ATPase","complex","required","for","the","efficient","dislocation","of","ER-lumenal","degradation","substrates",",","and","their","subsequent","proteolysis","by","the","proteasome",".","In","budding","yeast",",","this","complex","includes","Cdc48p",",","Npl4p","and","Ufd1p","proteins","."),4076588). assertion_content_comment('oboGo_CDP_4_Dehydro_6_DeoxyglucoseReductaseActivity',s("Catalysis","of","the","reaction",":","H2O","+","NAD","(","P",")","+","+","CDP-4-dehydro-3",",","6-dideoxy-D-glucose","=","NAD","(","P",")","H","+","CDP-4-dehydro-6-deoxy-D-glucose","."),4364664). assertion_content_comment('oboGo_CDPAbequoseepimeraseactivity',s("Catalysis","of","the","reaction",":","CDP-3",",","6-dideoxy-D-glucose","=","CDP-3",",","6-dideoxy-D-mannose","."),4373484). assertion_content_comment('oboGo_CDPAcylglyceroloArachidonoyltransferaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","CDP-acylglycerol","+","arachidonyl-CoA","=","CDP-diacylglycerol","+","CoA","."),4366154). assertion_content_comment('oboGo_CDPAlcoholphosphatidyltransferaseactivity',s("Catalysis","of","the","reaction",":","CDP","+","alcohol","=","CMP","+","phosphatidyl","alcohol","."),4189933). assertion_content_comment('oboGo_CDPAlcoholphosphotransferaseactivity',s("Catalysis","of","the","transfer","of","a","CDP-alcohol","group","from","one","compound","to","another","."),4255736). assertion_content_comment('oboGo_CDPCholinepathway',s("The","phosphatidylcholine","biosynthetic","process","that","begins","with","the","phosphorylation","of","choline","and","ends","with","the","combination","of","CDP-choline","with","diacylglycerol","to","form","phosphatidylcholine","."),4230543). assertion_content_comment('oboGo_CDPDiacylglycerolbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","CDP-diacylglycerol",",","CDP-1",",","2-diacylglycerol",",","a","substance","composed","of","diacylglycerol","in","glycosidic","linkage","with","cytidine","diphosphate","."),4302579). assertion_content_comment('oboGo_CDPDiacylglycerolcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","CDP-diacylglycerol",",","CDP-1",",","2-diacylglycerol",",","a","substance","composed","of","diacylglycerol","in","glycosidic","linkage","with","cytidine","diphosphate","."),4350091). assertion_content_comment('oboGo_CDPDiacylglyceroldiphosphataseactivity',s("Catalysis","of","the","reaction",":","CDP-diacylglycerol","+","H","(","2",")","O","=","a","phosphatidate","+","CMP","+","2","H","(","+",")"),4252084). assertion_content_comment('oboGo_CDP_Diacylglycerol_Glycerol_3_Phosphate3_PhosphatidyltransferaseActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","CDP-diacylglycerol","=","3-","(","3-sn-phosphatidyl",")","-sn-glycerol","1-phosphate","+","CMP","+","H","(","+",")"),4253704). assertion_content_comment('oboGo_CDPDiacylglycerolInositol3Phosphatidyltransferaseactivity',s("Catalysis","of","the","reaction",":","myo-inositol","+","CDP-diacylglycerol","=","1-phosphatidyl-1D-myo-inositol","+","CMP","+","H","(","+",")"),4189935). assertion_content_comment('oboGo_CDPDiacylglycerolmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","CDP-diacylglycerol",",","CDP-1",",","2-diacylglycerol",",","a","substance","composed","of","diacylglycerol","in","glycosidic","linkage","with","cytidine","diphosphate",".","It","is","a","common","intermediate","in","phospholipid","biosynthesis","."),4302575). assertion_content_comment('oboGo_CDPDiacylglycerolPhosphatidylglycerolphosphatidyltransferaseactivity',s("Catalysis","of","the","reaction",":","CDP-diacylglycerol","+","phosphatidylglycerol","=","CMP","+","diphosphatidylglycerol","."),4318283). assertion_content_comment('oboGo_CDPDiacylglycerolSerineoPhosphatidyltransferaseactivity',s("Catalysis","of","the","reaction",":","CDP-diacylglycerol","+","L-serine","=","CMP","+","O-sn-phosphatidyl-L-serine","."),4190016). assertion_content_comment('oboGo_CDPGlucose46Dehydrataseactivity',s("Catalysis","of","the","reaction",":","CDP-D-glucose","=","CDP-4-dehydro-6-deoxy-D-glucose","+","H","(","2",")","O","."),4373503). assertion_content_comment('oboGo_CDPGlyceroldiphosphataseactivity',s("Catalysis","of","the","reaction",":","CDP-glycerol","+","H","(","2",")","O","=","sn-glycerol","3-phosphate","+","CMP","+","2","H","(","+",")"),4373517). assertion_content_comment('oboGo_CDPGlycerolglycerophosphotransferaseactivity',s("Catalysis","of","the","reaction",":","glycerophosphate","(","n",")","+","CDP-glycerol","=","glycerophosphate","(","n","+","1",")","+","CMP","."),4368061). assertion_content_comment('oboGo_CDPRibitolribitolphosphotransferaseactivity',s("Catalysis","of","the","reaction",":","ribitol","phosphate","(","n",")","+","CDP-ribitol","=","ribitol","phosphate","(","n","+","1",")","+","CMP","."),4368043). assertion_content_comment('oboGo_CellAdhesionInvolvedInMultiSpeciesbiofilmformation',s("The","attachment","of","a","cell","to","a","surface",",","via","cell","adhesion","molecules",",","contributing","to","the","formation","of","a","biofilm","composed","of","microorganisms","of","different","species","."),4095291). assertion_content_comment('oboGo_CellAdhesionInvolvedInSingleSpeciesbiofilmformationinoronhostorganism',s("The","attachment","of","a","cell","to","either","a","host","cell","or","a","microbial","cell","of","the","same","species",",","or","to","an","underlying","host","substrate",",","such","as","the","extracellular","matrix",",","via","cell","adhesion","molecules",",","occurring","during","the","formation","of","a","biofilm","in","or","on","a","surface","in","a","host","species","."),4095269). 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assertion_content_comment('oboGo_CellularResponseToUVC',s("A","change","in","state","or","activity","of","a","cell","(","in","terms","of","movement",",","secretion",",","enzyme","production",",","gene","expression",",","etc.",")","as","a","result","of","a","UV-C","radiation","stimulus",".","UV-C","radiation","(","UV-C","light",")","spans","the","wavelengths","100","to","290","nm","."),4163338). assertion_content_comment('oboGo_CellularResponseToXRay',s("A","change","in","state","or","activity","of","a","cell","(","in","terms","of","movement",",","secretion",",","enzyme","production",",","gene","expression",",","etc.",")","as","a","result","of","X-ray","radiation",".","An","X-ray","is","a","form","of","electromagnetic","radiation","with","a","wavelength","in","the","range","of","10","nanometers","to","100","picometers","(","corresponding","to","frequencies","in","the","range","30","PHz","to","3","EHz",")"),4163491). assertion_content_comment('oboGo_Cellulose14BetaCellobiosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-beta-D-glucosidic","linkages","in","cellulose","and","cellotetraose",",","releasing","cellobiose","from","the","non-reducing","ends","of","the","chains","."),4304219). assertion_content_comment('oboGo_CellulosePolysulfataseactivity',s("Catalysis","of","the","hydrolysis","of","the","2-","and","3-sulfate","groups","of","the","polysulfates","of","cellulose","and","charonin","."),4343468). assertion_content_comment('oboGo_CelluloseSynthaseGDPFormingactivity',s("Catalysis","of","the","reaction",":","GDP-glucose","+","(","(","1",",","4",")","-beta-D-glucosyl",")","(","n",")","=","GDP","+","(","(","1",",","4",")","-beta-D-glucosyl",")","(","n","+","1",")"),4301568). assertion_content_comment('oboGo_CelluloseSynthaseUDPFormingactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","(","(","1",",","4",")","-beta-D-glucosyl",")","(","n",")","=","UDP","+","(","(","1",",","4",")","-beta-D-glucosyl",")","(","n","+","1",")"),4301529). assertion_content_comment('oboGo_CellWall13AlphaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1",",","3-alpha-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-alpha-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4130617). assertion_content_comment('oboGo_CellWall13AlphaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","alpha-1",",","3","glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-alpha-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4130612). assertion_content_comment('oboGo_CellWall13BetaDGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1",",","3-beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4111534). assertion_content_comment('oboGo_CellWall13BetaDGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-1",",","3","glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4111451). assertion_content_comment('oboGo_CellWallBetaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4111527). assertion_content_comment('oboGo_CellWallBetaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","cells","."),4074624). assertion_content_comment('oboGo_CellWallBoundedperiplasmicspace',s("The","region","between","the","plasma","membrane","and","the","cell","wall",",","as","found","in","organisms","such","as","yeast","and","Gram","positive","bacteria",".","The","region","is","thinner","than","the","equivalent","in","Gram","negative","bacteria","."),4311870). assertion_content_comment('oboGo_CellWallHydroxyprolineRichglycoproteinmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","cell","wall","hydroxyproline-rich","glycoprotein","that","consist","of","a","core-protein","backbone","O-glycosylated","by","one","or","more","complex","carbohydrates","."),4332975). assertion_content_comment('oboGo_CellWallInnerMembrane_3',s("OBSOLETE",".","The","peptidoglycan","layer","of","the","cell","wall","of","Gram-negative","bacteria","."),4306613). assertion_content_comment('oboGo_CellWallMacromoleculeCatabolicProcessInvolvedInFungalTypecellwalldisassembly',s("The","chemical","reactions","and","pathways","that","result","in","the","breakdown","of","macromolecules","that","form","part","of","a","cell","wall",",","and","contributes","to","the","breakdown","of","the","fungal-type","cell","wall","."),4075632). assertion_content_comment('oboGo_CenH3Containingnucleosomeassemblyatcentromere',s("The","formation","of","nucleosomes","containing","the","histone","H3","variant","CenH3","(","also","called","CENP-A",")","to","form","centromeric","chromatin",";","occurs","outside","the","context","of","DNA","replication","."),4361142). assertion_content_comment('oboGo_CentrioleCentriolecohesion',s("The","process","in","which","the","two","centrioles","within","a","centrosome","remain","tightly","paired","."),4061180). assertion_content_comment('oboGo_CentromereSpecificnucleosomebinding',s("Interacting","selectively","and","non-covalently","with","a","centromere-specific","nucleosome",",","a","form","of","nucleosome","located","only","at","the","centromere",",","in","which","the","histone","H3","is","replaced","by","the","variant","form","CENP-A","(","sometimes","known","as","CenH3",")"),4074161). assertion_content_comment('oboGo_CentromereSpecificnucleosome',s("A","form","of","nucleosome","located","only","at","the","centromere",",","in","which","the","histone","H3","is","replaced","by","the","variant","form","CENP-A","(","sometimes","known","as","CenH3",")"),4094626). assertion_content_comment('oboGo_CentrosomeTemplatedmicrotubulenucleation',s("The","'","de","novo","'","formation","of","a","microtubule",",","in","which","tubulin","heterodimers","form","metastable","oligomeric","aggregates","from","the","centrosome","."),4155614). assertion_content_comment('oboGo_CephalosporinCdeacetylaseactivity',s("Catalysis","of","the","reaction",":","cephalosporin","C","+","H","(","2",")","O","=","acetate","+","deacetylcephalosporin","C","+","H","(","+",")"),4373427). assertion_content_comment('oboGo_CephalosporinCtransaminaseactivity',s("Catalysis","of","the","reaction",":","(","7R",")","-7-","(","5-carboxylato-5-oxopentanamido",")","deacetylcephalosporanate","+","D-glutamate","=","2-oxoglutarate","+","cephalosporin","C","."),4373413). assertion_content_comment('oboGo_CerebellarPurkinjeCellGranulecellprecursorcellsignalinginvolvedinregulationofgranulecellprecursorcellproliferation',s("The","process","that","mediates","the","transfer","of","information","from","Purkinje","cells","to","granule","cell","precursors","resulting","in","an","increase","in","rate","of","granule","cell","precursor","cell","proliferation","."),4048747). assertion_content_comment('oboGo_CerebralCortexTangentialMigrationUsingCellAxoninteractions',s("The","movement","of","cerebral","cortex","neuronal","precursors","tangentially","through","the","cortex","using","interaction","of","the","migrating","cells","with","axons","of","other","neurons","."),4051321). assertion_content_comment('oboGo_CerebralCortexTangentialMigrationUsingCellCellinteractions',s("The","process","in","which","neurons","interact","with","each","other","to","promote","migration","along","a","tangential","plane","."),4051128). assertion_content_comment('oboGo_CerebrosideSulfataseactivity',s("Catalysis","of","the","reaction",":","a","cerebroside","3-sulfate","+","H2O","=","a","cerebroside","+","sulfate","."),4212226). assertion_content_comment('oboGo_CFiber',s("The","axon","of","a","dorsal","root","ganglion","cell","that","are","responsive","to","pain","and","temperature",".","C-fibers","are","small","in","diameter","(","0.2-1.5","um",")","and","unmyelinated","."),4288130). assertion_content_comment('oboGo_CFTRNherfEzrincomplex',s("A","protein","complex","that","contains","ezrin",",","Na","+","/H","+","exchanger","regulatory","factor","(","NHERF",",","also","called","EBP50",")",",","and","two","copies","of","the","cystic","fibrosis","transmembrane","conductance","regulator","(","CFTR",")","The","CFTR","molecules","interact","with","NHERF","via","their","cytoplasmic","tail","domains",";","the","complex","is","thought","to","link","the","CFTR","channel","to","the","actin","cytoskeleton","and","contribute","to","the","regulation","of","channel","activity","."),4354511). assertion_content_comment('oboGo_CGACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CGA","codon","."),4339812). assertion_content_comment('oboGo_CGCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CGC","codon","."),4339823). assertion_content_comment('oboGo_CGGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CGG","codon","."),4339870). assertion_content_comment('oboGo_CGMPDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","presence","of","cGMP","."),4202538). assertion_content_comment('oboGo_CGMPInhibitedcyclicNucleotidephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","nucleoside","3","'",",","5","'","-cyclic","phosphate","+","H2O","=","nucleoside","5","'","-phosphate",";","catalytic","activity","is","decreased","in","the","presence","of","cGMP","."),4212105). assertion_content_comment('oboGo_CGMPMediatedsignaling',s("A","series","of","molecular","signals","in","which","a","cell","uses","cyclic","GMP","to","convert","an","extracellular","signal","into","a","response","."),4024721). assertion_content_comment('oboGo_CGMPStimulatedcyclicNucleotidephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","nucleoside","3","'",",","5","'","-cyclic","phosphate","+","H2O","=","nucleoside","5","'","-phosphate",";","catalytic","activity","is","increased","in","the","presence","of","cGMP","."),4212096). assertion_content_comment('oboGo_CGUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CGU","codon","."),4339926). assertion_content_comment('oboGo_ChannelConductanceControllingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","An","animal","enzyme","that","is","active","in","forming","a","chloride","channel",",","the","absence","of","which","brings","about","cystic","fibrosis",".","It","is","also","involved","in","the","functioning","of","other","transmembrane","channels","."),4217919). assertion_content_comment('oboGo_ChannelFormingionophoreactivity',s("Enables","transport","of","a","solute","across","a","membrane",".","This","kind","of","transporter","interacts","much","more","weakly","with","the","solute","than","the","carrier","does",".","It","is","an","aqueous","pore","that","extends","across","the","membrane",".","It","may","change","from","closed","to","open","and","back",".","It","transports","faster","than","a","carrier",".","It","is","always","passive","."),4333310). assertion_content_comment('oboGo_ChannelFormingtoxinactivity',s("OBSOLETE",".","A","toxin","that","exerts","its","effects","by","forming","a","channel","in","a","membrane","that","allows","the","unregulated","passage","of","substances","into","and","out","of","the","cell","."),4291778). assertion_content_comment('oboGo_ChaperoneCofactorDependentproteinrefolding',s("The","process","of","assisting","in","the","restoration","of","the","biological","activity","of","an","unfolded","or","misfolded","protein",",","which","is","dependent","on","additional","protein","cofactors",".","This","process","occurs","over","one","or","several","cycles","of","nucleotide","hydrolysis-dependent","binding","and","release","."),4173451). assertion_content_comment('oboGo_ChaperoneMediatedproteincomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","set","of","components","to","form","a","protein","complex",",","mediated","by","chaperone","molecules","that","do","not","form","part","of","the","finished","complex","."),4149758). assertion_content_comment('oboGo_ChaperoneMediatedproteinfolding',s("The","process","of","inhibiting","aggregation","and","assisting","in","the","covalent","and","noncovalent","assembly","of","single","chain","polypeptides","or","multisubunit","complexes","into","the","correct","tertiary","structure","that","is","dependent","on","interaction","with","a","chaperone","."),4155961). assertion_content_comment('oboGo_ChaperoneMediatedproteintransportacrossperiplasmicspace',s("The","directed","movement","of","proteins","from","the","plasma","membrane","across","the","periplasmic","space","to","the","outer","membrane",",","mediated","by","chaperone","molecules","that","bind","to","the","transported","proteins",".","This","process","has","been","observed","in","Gram-negative","bacteria","."),4158731). assertion_content_comment('oboGo_ChaperoneMediatedproteintransport',s("The","directed","movement","of","proteins","into",",","out","of","or","within","a","cell",",","or","between","cells",",","mediated","by","chaperone","molecules","that","bind","to","the","transported","proteins","."),4158719). assertion_content_comment('oboGo_ChaperoninContainingtComplex',s("A","multisubunit","ring-shaped","complex","that","mediates","protein","folding","in","the","cytosol","without","a","cofactor","."),4221751). assertion_content_comment('oboGo_ChargedTrnaaminoacidmodification',s("The","covalent","alteration","of","an","amino","acid","charged","on","a","tRNA","before","it","is","incorporated","into","a","protein",",","as","in","N-formylmethionine",",","selenocysteine","or","pyrrolysine","."),4168783). assertion_content_comment('oboGo_ChemiMechanicalcoupling',s("OBSOLETE",".","The","conversion","of","chemical","energy","into","mechanical","work","(","as","in","the","contraction","of","a","muscle",")"),4232350). assertion_content_comment('oboGo_ChemokineCCmotifligand11production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","11","(","CCL11",",","also","known","as","eotaxin-1",")","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4168759). assertion_content_comment('oboGo_ChemokineCCmotifligand12binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","12","."),4380899). assertion_content_comment('oboGo_ChemokineCCmotifligand19binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","19","."),4381205). assertion_content_comment('oboGo_ChemokineCCmotifligand1production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","1","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4129991). assertion_content_comment('oboGo_ChemokineCCmotifligand21binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","21","."),4381195). assertion_content_comment('oboGo_ChemokineCCmotifligand22production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","22","(","CCL22",")","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4167940). assertion_content_comment('oboGo_ChemokineCCmotifligand2binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","2","."),4380889). assertion_content_comment('oboGo_ChemokineCCmotifligand4production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","4","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4130058). assertion_content_comment('oboGo_ChemokineCCmotifligand5binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","5","."),4169240). assertion_content_comment('oboGo_ChemokineCCmotifligand5production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","5","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4129913). assertion_content_comment('oboGo_ChemokineCCmotifligand5signalingpathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","the","chemokine","CCL5","binding","to","a","cell","surface","receptor","."),4380283). assertion_content_comment('oboGo_ChemokineCCmotifligand6production',s("The","appearance","of","chemokine","(","C-C","motif",")","ligand","6","(","CCL6",")","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4084038). assertion_content_comment('oboGo_ChemokineCCmotifligand6secretion',s("The","regulated","release","of","chemokine","(","C-C","motif",")","ligand","6","(","CCL6",")","from","a","cell","or","group","of","cells","."),4084059). assertion_content_comment('oboGo_ChemokineCCmotifligand7binding',s("Interacting","selectively","and","non-covalently","with","chemokine","(","C-C","motif",")","ligand","7","."),4380869). assertion_content_comment('oboGo_ChemokineCXCmotifligand1production',s("The","appearance","of","chemokine","(","C-X-C","motif",")","ligand","1","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4143233). assertion_content_comment('oboGo_ChemokineCXCmotifligand2production',s("The","appearance","of","chemokine","(","C-X-C","motif",")","ligand","1","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4143275). assertion_content_comment('oboGo_ChemokineCXCmotifligand9production',s("The","appearance","of","chemokine","(","C-X-C","motif",")","ligand","9","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4083208). assertion_content_comment('oboGo_ChemokineMediatedsignalingpathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","a","chemokine","binding","to","a","cell","surface","receptor","."),4133043). assertion_content_comment('oboGo_ChemokineReceptorLikereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4360465). assertion_content_comment('oboGo_ChitinBasedcuticleattachmenttoepithelium',s("Attaching","of","a","chitin-containing","cuticle","to","the","epithelium","underlying","it",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4081732). assertion_content_comment('oboGo_ChitinBasedcuticledevelopment',s("Synthesis","and","deposition","of","a","chitin-based","noncellular",",","hardened",",","or","membranous","secretion","from","an","epithelial","sheet",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4010159). assertion_content_comment('oboGo_ChitinBasedcuticletanning',s("The","cross-linking","of","chitin","and","other","cuticle","proteins",",","rendering","them","insoluble","and","hardening","the","cuticle",".","This","process","generally","darkens","the","color","of","the","cuticle","."),4015248). assertion_content_comment('oboGo_ChitinBasedembryoniccuticlebiosyntheticprocess',s("Synthesis",",","including","the","chemical","reactions","and","pathways","resulting","in","the","formation","of","chitin","and","other","components",",","and","deposition","of","a","chitin-based","embryonic","cuticle","by","the","underlying","epidermal","epithelium",".","This","tough",",","waterproof","cuticle","layer","is","essential","to","provide","structural","integrity","of","the","larval","body",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4255033). assertion_content_comment('oboGo_ChitinBasedlarvalcuticlepatternformation',s("The","process","that","gives","rise","to","the","patterns","of","cell","differentiation","in","the","chitin-based","larval","cuticle",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4071234). assertion_content_comment('oboGo_ChitobiosyldiphosphodolicholBetaMannosyltransferaseactivity',s("Catalysis","of","the","reaction",":","GDP-mannose","+","chitobiosyldiphosphodolichol","=","GDP","+","beta-D-mannosylchitobiosyldiphosphodolichol","."),4204326). assertion_content_comment('oboGo_ChloramphenicolOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","chloramphenicol","=","chloramphenicol","3-acetate","+","CoA","."),4250721). assertion_content_comment('oboGo_ChloridazonCatecholdioxygenaseactivity',s("Catalysis","of","the","reaction",":","5-amino-4-chloro-2-","(","2",",","3-dihydroxyphenyl",")","pyridazin-3","(","2H",")","-one","+","O","(","2",")","=","5-amino-4-chloro-2-","(","2-hydroxymuconoyl",")","pyridazin-3","(","2H",")","-one","+","2","H","(","+",")"),4373383). assertion_content_comment('oboGo_ChlorideActivatedpotassiumchannelactivity',s("Catalysis","of","the","chloride","concentration-regulatable","energy-independent","passage","of","potassium","ions","across","a","lipid","bilayer","down","a","concentration","gradient","."),4180224). assertion_content_comment('oboGo_ChlorideTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Cl-","(","out",")","=","ADP","+","phosphate","+","Cl-","(","in",")"),4252878). assertion_content_comment('oboGo_ChloriteO2Lyaseactivity',s("Catalysis","of","the","reaction",":","chloride","+","O","(","2",")","=","chlorite","."),4268061). assertion_content_comment('oboGo_Chlorocatechol12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","3",",","6-dichlorocatechol","+","O2","=","2","H","+","+","2",",","5-dichloro-cis",",","cis-muconate","."),4278728). assertion_content_comment('oboGo_ChlorogenateGlucarateoHydroxycinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucarate","+","chlorogenate","=","(","-",")","-quinate","+","2-O-caffeoylglucarate","."),4367810). assertion_content_comment('oboGo_Chlorophenol4Monooxygenaseactivity',s("Catalysis","of","the","addition","or","substitution","of","an","OH","group","on","C4","of","a","halogenated","phenol","."),4276322). assertion_content_comment('oboGo_ChlorophenolOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","trichlorophenol","=","S-adenosyl-L-homocysteine","+","trichloroanisole","."),4309123). assertion_content_comment('oboGo_ChlorophyllABiosyntheticProcessViaGeranylgeranylChlorophylla',s("The","chemical","reactions","and","pathways","leading","to","the","formation","of","chlorophyll","a",",","via","the","intermediate","geranylgeranyl-chlorophyll","a","."),4339003). assertion_content_comment('oboGo_ChloroplastNucleussignalingpathway',s("The","process","in","which","a","molecular","signal","is","transduced","between","the","chloroplast","and","nucleus",",","such","that","expression","of","nuclear","encoding","photosynthetic","proteins","is","coupled","with","chloroplast","biogenesis","."),4330007). assertion_content_comment('oboGo_ChloroplastProteinTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","drives","the","transport","of","proteins","into","the","chloroplast","stroma","."),4304928). assertion_content_comment('oboGo_ChloroplastProtonTransportingatpsynthasecomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","proton-transporting","ATP","synthase","in","the","chloroplast","thylakoid","membrane","."),4063545). assertion_content_comment('oboGo_ChloroplastProtonTransportingatpsynthasecomplexcatalyticcorecf1',s("The","catalytic","sector","of","the","mitochondrial","hydrogen-transporting","ATP","synthase",";","it","comprises","the","catalytic","core","and","central","stalk",",","and","is","peripherally","associated","with","the","chloroplast","thylakoid","membrane","when","the","entire","ATP","synthase","is","assembled",".","The","chloroplast","F0","domain","contains","three","alpha",",","three","beta",",","one","gamma",",","one","delta",",","and","one","epsilon","subunits","."),4065451). assertion_content_comment('oboGo_ChloroplastProtonTransportingatpsynthasecomplexcouplingfactorcfo',s("All","non-F1","subunits","of","the","chloroplast","hydrogen-transporting","ATP","synthase",",","including","integral","and","peripheral","chloroplast","thylakoid","membrane","proteins","."),4065437). assertion_content_comment('oboGo_ChloroplastProtonTransportingatpsynthasecomplex',s("A","proton-transporting","ATP","synthase","complex","found","in","the","chloroplast","thylakoid","membrane",";","it","catalyzes","the","phosphorylation","of","ADP","to","ATP","during","photo-phosphorylation","."),4065422). assertion_content_comment('oboGo_ChloroplastTypeferredoxin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259474). assertion_content_comment('oboGo_Cholate12Alphadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","cholate","+","NADP","(","+",")","=","3alpha",",","7alpha-dihydroxy-12-oxo-5beta-cholanate","+","H","(","+",")","+","NADPH","."),4364091). assertion_content_comment('oboGo_Cholate7AlphaDehydrogenaseactivity',s("Catalysis","of","the","reaction",":","cholate","+","NAD","(","+",")","=","3alpha",",","12alpha-dihydroxy-7-oxo-5beta-cholanate","+","H","(","+",")","+","NADH","."),4252194). assertion_content_comment('oboGo_CholateCoaligaseactivity',s("Catalysis","of","the","reactions",":","(","1",")","ATP","+","cholate","+","CoA","=","AMP","+","diphosphate","+","choloyl-CoA","and","(","2",")","ATP","+","(","25R",")","-3alpha",",","7alpha",",","12alpha-trihydroxy-5beta-cholestan-26-oate","+","CoA","=","AMP","+","diphosphate","+","(","25R",")","-3alpha",",","7alpha",",","12alpha-trihydroxy-5beta-cholestanoyl-CoA","."),4373258). assertion_content_comment('oboGo_Cholest_5_Ene_3_Beta7_Alpha_Diol3_Beta_DehydrogenaseActivity',s("Catalysis","of","the","reaction",":","NAD","+","+","7-alpha-hydroxycholesterol","=","NADH","+","H","+","+","7-alpha-hydroxycholest-4-en-3-one","."),4364077). assertion_content_comment('oboGo_Cholestanetetraol26Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","5-beta-cholestane-3-alpha",",","7-alpha",",","12-alpha",",","26-tetraol","+","NAD","+","=","3-alpha",",","7-alpha",",","12-alpha-trihydroxy-5-beta-cholestan-26-al","+","NADH","."),4373244). assertion_content_comment('oboGo_Cholestanetriol26Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","5-beta-cholestane-3-alpha",",","7-alpha",",","12-alpha-triol","+","NADPH","+","O2","=","5-beta-cholestane-3-alpha",",","7-alpha",",","12-alpha",",","26-tetraol","+","NADP","+","+","H2O","."),4373290). assertion_content_comment('oboGo_CholestenolDeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","5-alpha-cholest-7-en-3-beta-ol","=","5-alpha-cholest-8-en-3-beta-ol","."),4373149). assertion_content_comment('oboGo_Cholestenone5AlphaReductaseactivity',s("Catalysis","of","the","reaction",":","5alpha-cholestan-3-one","+","NADP","(","+",")","=","cholest-4-en-3-one","+","H","(","+",")","+","NADPH","."),4373160). assertion_content_comment('oboGo_Cholesterol24Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","cholesterol","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","(","24S",")","-24-hydroxycholesterol","+","H","(","2",")","O","+","NADP","(","+",")"),4342109). assertion_content_comment('oboGo_Cholesterol25Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","cholesterol","+","O","(","2",")","=","25-hydroxycholesterol","+","A","+","H","(","2",")","O","."),4361357). assertion_content_comment('oboGo_Cholesterol26Hydroxylaseactivity',s("Catalysis","of","the","hydroxylation","of","cholesterol","at","position","26","of","the","side","chain",",","to","produce","26-hydroxycholesterol","."),4319222). assertion_content_comment('oboGo_Cholesterol_56_OxideHydrolaseActivity',s("Catalysis","of","the","reactions",":","5",",","6alpha-epoxy-5alpha-cholestan-3beta-ol","+","H2O","=","cholestane-3beta-5alpha",",","6beta-triol",",","and","5",",","6beta-epoxy-5beta-cholestan-3beta-ol","+","H2O","=","cholestane-3beta-5alpha",",","6beta-triol","."),4344566). assertion_content_comment('oboGo_Cholesterol7AlphaMonooxygenaseactivity',s("Catalysis","of","the","reaction",":","cholesterol","+","NADPH","+","H","+","+","O2","=","7-alpha-hydroxycholesterol","+","NADP","+","+","H2O","."),4246682). assertion_content_comment('oboGo_CholesterolBiosyntheticProcessVia2425Dihydrolanosterol',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","cholesterol",",","cholest-5-en-3","beta-ol",",","via","the","intermediate","24",",","25-dihydrolanosterol","."),4339331). assertion_content_comment('oboGo_CholesterolMonooxygenaseSideChainCleavingactivity',s("Catalysis","of","the","reaction",":","cholesterol","+","reduced","adrenal","ferredoxin","+","O2","=","pregnenolone","+","4-methylpentanal","+","oxidized","adrenal","ferredoxin","+","H2O","."),4255482). assertion_content_comment('oboGo_CholesterolOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","cholesterol","=","a","cholesterol","ester","+","CoA","."),4349407). assertion_content_comment('oboGo_CholesterolUDPGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","sterol","=","UDP","+","O-glucosyl-cholesterol","."),4283348). assertion_content_comment('oboGo_CholineBiosyntheticProcessViaCDPCholine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","choline","(","2-hydroxyethyltrimethylammonium",")",",","via","the","intermediate","CDP-choline","."),4339093). assertion_content_comment('oboGo_CholineBiosyntheticProcessViaNMonomethylethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","choline","(","2-hydroxyethyltrimethylammonium",")",",","via","the","intermediate","N-monomethylethanolamine","."),4339135). assertion_content_comment('oboGo_CholineBiosyntheticProcessViaPhosphorylEthanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","choline","(","2-hydroxyethyltrimethylammonium",")",",","via","the","intermediate","phosphoryl-ethanolamine","."),4339121). assertion_content_comment('oboGo_CholineOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","choline","=","acetylcholine","+","CoA","."),4211919). assertion_content_comment('oboGo_Choline_Oxygen1Oxidoreductaseactivity',s("Catalysis","of","the","reaction",":","choline","+","O2","=","betaine","aldehyde","+","hydrogen","peroxide","."),4341978). assertion_content_comment('oboGo_CholinePhosphatecytidylyltransferaseactivity',s("Catalysis","of","the","reaction",":","CTP","+","choline","phosphate","=","diphosphate","+","CDP-choline","."),4211897). assertion_content_comment('oboGo_CholineSulfataseactivity',s("Catalysis","of","the","reaction",":","choline","sulfate","+","H","(","2",")","O","=","choline","+","H","(","+",")","+","sulfate","."),4373186). assertion_content_comment('oboGo_CholineTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",",","to","directly","drive","the","transport","of","choline","across","a","membrane","."),4337949). assertion_content_comment('oboGo_CholoylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","choloyl-CoA","+","H2O","=","cholate","+","CoA","."),4343418). assertion_content_comment('oboGo_Chondro_4_SulfataseActivity',s("Catalysis","of","the","reaction",":","4-deoxy-beta-D-gluc-4-enuronosyl-","(","1-","&","gt",";","3",")","-N-acetyl-D-galactosamine","4-sulfate","+","H","(","2",")","O","=","4-deoxy-beta-D-gluc-4-enuronosyl-","(","1-","&","gt",";","3",")","-N-acetyl-D-galactosamine","+","H","(","+",")","+","sulfate","."),4344089). assertion_content_comment('oboGo_Chondro_6_SulfataseActivity',s("Catalysis","of","the","reaction",":","4-deoxy-beta-D-gluc-4-enuronosyl-","(","1-","&","gt",";","3",")","-N-acetyl-D-galactosamine","6-sulfate","+","H","(","2",")","O","=","4-deoxy-beta-D-gluc-4-enuronosyl-","(","1-","&","gt",";","3",")","-N-acetyl-D-galactosamine","+","H","(","+",")","+","sulfate","."),4344079). assertion_content_comment('oboGo_Chondroitin2OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","chondroitin","=","adenosine","3","'",",","5","'","-bisphosphate","+","chondroitin","2","'","-O-sulfate",".","Results","in","sulfation","of","glucuronic","acid","and","iduronic","acid","residues","."),4357495). assertion_content_comment('oboGo_Chondroitin4Sulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","chondroitin","=","adenosine","3","'",",","5","'","-bisphosphate","+","chondroitin","4","'","-sulfate","."),4373219). assertion_content_comment('oboGo_Chondroitin6Sulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","chondroitin","=","adenosine","3","'",",","5","'","-bisphosphate","+","chondroitin","6","'","-sulfate","."),4254044). assertion_content_comment('oboGo_ChondroitinGlucuronate5Epimeraseactivity',s("Catalysis","of","the","reaction",":","chondroitin","D-glucuronate","=","dermatan","L-iduronate","."),4373230). assertion_content_comment('oboGo_ChondroitinSulfateAbcendolyaseactivity',s("Catalysis","of","the","endolytic","cleavage","of","beta-1",",","4-galactosaminic","bonds","between","N-acetylgalactosamine","and","either","D-glucuronic","acid","or","L-iduronic","acid","to","produce","a","mixture","of","Delta4-unsaturated","oligosaccharides","of","different","sizes","that","are","ultimately","degraded","to","Delta4-unsaturated","tetra-","and","disaccharides","."),4360549). assertion_content_comment('oboGo_ChondroitinSulfateAbcexolyaseactivity',s("Catalysis","of","the","exolytic","cleavage","of","disaccharide","residues","from","the","non-reducing","ends","of","both","polymeric","chondroitin","sulfates","and","their","oligosaccharide","fragments","."),4360566). assertion_content_comment('oboGo_ChorioAllantoicfusion',s("The","cell-cell","adhesion","process","in","which","the","cells","of","the","chorion","fuse","to","the","cells","of","the","allantois","."),4112644). assertion_content_comment('oboGo_ChorionContainingeggshellformation',s("The","construction","of","a","chorion-containing","eggshell",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4018695). assertion_content_comment('oboGo_ChorionContainingeggshellpatternformation',s("The","regionalization","process","that","gives","rise","to","the","structural","pattern","of","a","chorion-containing","eggshell","such","as","those","found","in","insects","."),4046315). assertion_content_comment('oboGo_ChromatinInsulatorSequenceBinding_7',s("Interacting","selectively","and","non-covalently","and","stoichiometrically","with","a","chromatin","insulator","sequence",",","a","DNA","sequence","that","prevents","enhancer-mediated","activation","or","repression","of","transcription","."),4222556). assertion_content_comment('oboGo_ChromatinMediatedmaintenanceoftranscription',s("Maintenance","of","transcription","by","remodelling","of","chromatin","into","an","'","open","configuration","'","Once","established",",","this","regulation","is","mitotically","stable","and","is","maintained","over","many","cell","divisions",".","It","is","also","heritable","."),4222415). assertion_content_comment('oboGo_ChromatinSilencingAtSilentMatingTypecassette',s("Repression","of","transcription","at","silent","mating-type","loci","by","alteration","of","the","structure","of","chromatin","."),4083163). assertion_content_comment('oboGo_ChromatinTemplatedmicrotubulenucleation',s("The","'","de","novo","'","formation","of","a","microtubule",",","in","which","tubulin","heterodimers","form","metastable","oligomeric","aggregates","from","chromatin","."),4155605). assertion_content_comment('oboGo_ChromosomeSegregationDirectingcomplex',s("A","trimeric","protein","complex","which","in","E",".","coli","is","composed","of","the","subunits","MreB",",","MreC","and","MreD",".","The","complex","directs","longitudinal","cell","wall","synthesis",",","maintaining","cell","morphology","."),4328618). assertion_content_comment('oboGo_ChronicInflammatoryResponseToNonAntigenicstimulus',s("A","chronic","inflammatory","response","to","a","non-antigenic","stimulus","such","as","heat","or","physical","trauma","."),4000499). assertion_content_comment('oboGo_CiliaryNeurotrophicFactorMediatedsignalingpathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","ciliary","neurotrophic","factor","binding","to","a","cell","surface","receptor","."),4179891). assertion_content_comment('oboGo_CinnamateBetaDGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","trans-cinnamate","+","UDP-D-glucose","=","1-O-trans-cinnamoyl-beta-D-glucopyranose","+","UDP","."),4266645). assertion_content_comment('oboGo_CinnamoylCoa_PhenyllactatecoaTransferaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-3-phenyllactate","+","[","(","2R",",","3S",",","4R",",","5R",")","-5-","(","6-amino-9H-purin-9-yl",")","-4-hydroxy-3-","(","phosphonatooxy",")","oxolan-2-yl","]","methyl","{","[","(","3R",")","-3-hydroxy-2",",","2-dimethyl-3-","(","{","2-","[","(","2-","{","[","(","2E",")","-3-phenylprop-2-enoyl","]","sulfanyl","}","ethyl",")","carbamoyl","]","ethyl","}","carbamoyl",")","propyl","phosphonato","]","oxy","}","phosphonate","=","(","R",")","-3-phenyllactoyl-CoA","+","trans-cinnamate","."),4327845). assertion_content_comment('oboGo_CinnamoylCoareductaseactivity',s("Catalysis","of","the","reaction",":","cinnamaldehyde","+","CoA","+","NADP","+","=","cinnamoyl-CoA","+","NADPH","+","H","+"),4305844). assertion_content_comment('oboGo_CinnamylAlcoholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","cinnamyl","alcohol","+","NADP","+","=","cinnamaldehyde","+","NADPH","+","H","+"),4299395). assertion_content_comment('oboGo_CircadianSleepWakeCycleNonRemsleep',s("All","sleep","stages","in","the","circadian","sleep/wake","cycle","other","than","REM","sleep",".","These","stages","are","characterized","by","a","slowing","of","brain","waves","and","other","physiological","functions","."),4077283). assertion_content_comment('oboGo_Cis_12_Dihydro_12_DihydroxynaphthaleneDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydronaphthalene-1",",","2-diol","+","NAD","+","=","naphthalene-1",",","2-diol","+","NADH","+","H","+"),4278596). assertion_content_comment('oboGo_Cis_12_Dihydrobenzene_12_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydrobenzene-1",",","2-diol","+","NAD","+","=","catechol","+","NADH","+","H","+"),4278612). assertion_content_comment('oboGo_Cis_12_Dihydroxy_12_Dihydro_8_CarboxynaphthaleneDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydroxy-1",",","2-dihydro-8-carboxynaphthalene","=","1",",","2-dihydroxy-8-carboxynaphthalene","+","2","H","+","+","2","e-","."),4352100). assertion_content_comment('oboGo_Cis_12_Dihydroxy_4_Methylcyclohexa_35_Diene_1_CarboxylateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydroxy-4-methylcyclohexa-3",",","5-diene-1-carboxylate","+","NADP","+","=","4-methylcatechol","+","NADPH","+","H","+","+","CO2","."),4278360). assertion_content_comment('oboGo_Cis_12_Dihydroxycyclohexa_35_Diene_1_CarboxylateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydroxycyclohexa-3",",","5-diene-1-carboxylate","+","NAD","+","=","catechol","+","CO2","+","NADH","+","H","+"),4278563). assertion_content_comment('oboGo_Cis_14_Hydroxy_1013_Dioxo_7_HeptadecenoicAcidPeptidyl_AspartateEsterBiosyntheticProcessFromPeptidyl_AsparticAcid',s("The","modification","of","peptidyl-aspartic","acid","to","form","peptidyl-cis-14-hydroxy-10",",","13-dioxo-7-heptadecenoic","acid","aspartate","ester",",","typical","of","the","barley","lipid","transfer","protein","1","."),4233100). assertion_content_comment('oboGo_Cis_23_Dihydrobiphenyl_23_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-3-phenylcyclohexa-3",",","5-diene-1",",","2-diol","+","NAD","+","=","biphenyl-2",",","3-diol","+","NADH","+","H","+"),4278444). assertion_content_comment('oboGo_Cis_23_DihydrodiolDDTDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-2",",","3-dihydrodiol","DDT","+","NADP","+","=","NADPH","+","2",",","3-dihydroxy","DDT","."),4277231). assertion_content_comment('oboGo_Cis_2_Enoyl_CoAReductaseNADPHActivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","NADP","+","=","cis-2",",","3-dehydroacyl-CoA","+","NADPH","."),4374126). assertion_content_comment('oboGo_Cis_2_Methyl_5_Isopropylhexa_25_DienalDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-2-methyl-5-isopropylhexa-2",",","5-dienal","+","NAD","+","+","H2O","=","NADH","+","H","+","+","cis-2-methyl-5-isopropylhexa-2",",","5-dienoic","acid","."),4277511). assertion_content_comment('oboGo_Cis_2_Methyl_5_Isopropylhexa_25_Dienoate_CoALigaseActivity',s("Catalysis","of","the","reaction",":","cis-2-methyl-5-isopropylhexa-2",",","5-dienoic","acid","+","ATP","+","CoASH","=","cis-2-methyl-5-isopropylhexa-2",",","5-dienoyl-CoA","+","AMP","+","PPi","."),4348824). assertion_content_comment('oboGo_Cis_34_Dihydrophenanthrene_34_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","(","3S",",","4R",")","-3",",","4-dihydrophenanthrene-3",",","4-diol","+","NAD","(","+",")","=","H","(","+",")","+","NADH","+","phenanthrene-3",",","4-diol","."),4278573). assertion_content_comment('oboGo_Cis_34_Phenanthrenedihydrodiol_4_CarboxylateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-3",",","4-phenanthrenedihydrodiol-4-carboxylate","=","3",",","4-dihydroxyphenanthrene","+","H","+","+","2","e-","+","CO2","."),4350295). assertion_content_comment('oboGo_Cis_4_2_3_Hydroxy_Thionaphthenyl_2_Oxo_3_ButenoateIsomeraseActivity',s("Catalysis","of","the","reaction",":","cis-4-","(","2-","(","3-hydroxy",")","-thionaphthenyl",")","-2-oxo-3-butenoate","=","trans-4-","(","2-","(","3-hydroxy",")","-thionaphthenyl",")","-2-oxo-3-butenoate","."),4273811). assertion_content_comment('oboGo_Cis_45_Dihydroxy_45_DihydropyreneDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-4",",","5-dihydroxy-4",",","5-dihydropyrene","=","4",",","5-dihydroxypyrene","+","2","H","+","+","2","e-","."),4350322). assertion_content_comment('oboGo_Cis_4_8_Hydroxypyren_7_Yl_2_Oxobut_3_EnoateLyaseActivity',s("Catalysis","of","the","reaction",":","cis-4-","(","8-hydroxypyren-7-yl",")","-2-oxobut-3-enoate","=","10-oxabenzo","(","def",")","chrysen-9-one","+","formate","+","H","+"),4350457). assertion_content_comment('oboGo_Cis_910_Dihydroanthracene_910_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","cis-9",",","10-dihydroanthracene-9",",","10-diol","=","9",",","10-anthraquinone","+","4","H","+","+","4","e-","."),4350439). assertion_content_comment('oboGo_CisAconitamideamidaseactivity',s("Catalysis","of","the","reaction",":","cis-aconitamide","+","H2O","=","cis-aconitate","+","HN3","."),4351055). assertion_content_comment('oboGo_CisActingdnareplicationtermination',s("A","DNA","replication","termination","process","that","is","initiated","by","protein","binding","to","a","binding","site","on","the","same","chromosome",",","but","remote","from","the","termination","site",",","via","DNA","looping","or","chromosome","kissing","."),4168626). assertion_content_comment('oboGo_CisAssemblyOfPreCatalyticspliceosome',s("Assembly","of","a","spliceosomal","complex","containing","the","intact","pre-mRNA","and","all","of","the","spliceosomal","snRNPs",".","This","occurs","when","the","tri-snRNP","associates","with","the","pre-mRNA","and","associated","snRNPs","in","an","ATP-dependent","manner","."),3974700). assertion_content_comment('oboGo_CisChloroacrylicaciddehalogenaseactivity',s("Catalysis","of","the","reaction",":","cis-3-chloroacrylic","acid","+","H2O","=","H","+","+","HCl","+","malonate","semialdehyde","."),4274324). assertion_content_comment('oboGo_CisChlorobenzenedihydrodioldehydrogenaseactivity',s("Catalysis","of","the","conversion","of","a","di-","or","tetrachlorinated","dienol","to","the","corresponding","catechol","."),4278642). assertion_content_comment('oboGo_CisDihydroethylcatecholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","cis-1",",","2-dihydro-3-ethylcatechol","+","NAD","(","+",")","=","3-ethylcatechol","+","H","(","+",")","+","NADH","."),4278498). assertion_content_comment('oboGo_CisGolginetworkmembrane',s("The","lipid","bilayer","surrounding","any","of","the","compartments","that","make","up","the","cis-Golgi","network","."),4065735). assertion_content_comment('oboGo_CisGolginetwork',s("The","network","of","interconnected","tubular","and","cisternal","structures","located","at","the","convex","side","of","the","Golgi","apparatus",",","which","abuts","the","endoplasmic","reticulum","."),4052634). assertion_content_comment('oboGo_CisPCoumarateglucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","cis-4-coumarate","+","UDP-D-glucose","=","4","'","-O-beta-D-glucosyl-cis-4-coumarate","+","H","(","+",")","+","UDP","."),4277657). assertion_content_comment('oboGo_CisStilbeneOxidehydrolaseactivity',s("Catalysis","of","the","reaction",":","cis-stilbene","oxide","+","H2O","=","(","+",")","-","(","1R",",","2R",")","-1",",","2-diphenylethane-1",",","2-diol","."),4344592). assertion_content_comment('oboGo_CisTransisomeraseactivity',s("Catalysis","of","a","reaction","that","interconverts","cis","and","trans","isomers",".","Atoms","or","groups","are","termed","cis","or","trans","to","one","another","when","they","lie","respectively","on","the","same","or","on","opposite","sides","of","a","reference","plane","identifiable","as","common","among","stereoisomers","."),4192425). assertion_content_comment('oboGo_CisZeatinbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","cis-zeatin",",","(","2Z",")","-2-methyl-4-","(","9H-purin-6-ylamino",")","but-2-en-1-ol","."),4339571). assertion_content_comment('oboGo_CisZeatinmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","cis-zeatin",",","(","2Z",")","-2-methyl-4-","(","9H-purin-6-ylamino",")","but-2-en-1-ol","."),4338495). assertion_content_comment('oboGo_CisZeatinoBetaDGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","cis-zeatin","+","UDP-D-glucose","=","O-beta-D-glucosyl-cis-zeatin","+","H","(","+",")","+","UDP","."),4269673). assertion_content_comment('oboGo_CitramalateCoATransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","citramalate","=","acetate","+","(","3S",")","-citramalyl-CoA","."),4374107). assertion_content_comment('oboGo_CitrateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","citrate","+","CoA","=","(","3S",")","-citryl-CoA","+","ADP","+","H","(","+",")","+","phosphate","."),4374028). assertion_content_comment('oboGo_CitrateCoATransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","citrate","=","acetate","+","(","3S",")","-citryl-CoA","."),4250779). assertion_content_comment('oboGo_CitrateHydroLyasecisAconitateFormingactivity',s("Catalysis","of","the","reactions",":","citrate","=","cis-aconitate","+","H2O","."),4191617). assertion_content_comment('oboGo_CitrateLGlutamateligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","citrate","+","L-glutamate","=","ADP","+","phosphate","+","beta-citryl-L-glutamate","."),4157519). assertion_content_comment('oboGo_CitratePro_3S_LyaseActivity',s("Catalysis","of","the","reaction",":","citrate","=","acetate","+","oxaloacetate","."),4250790). assertion_content_comment('oboGo_CitratePro_3S_LyaseLigaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","acetate","+","(","citrate","(","pro-3S",")","-lyase",")","(","thiol","form",")","=","AMP","+","diphosphate","+","(","citrate","(","pro-3S",")","-lyase",")","(","acetyl","form",")"),4251805). assertion_content_comment('oboGo_Citrate_Pro_3S_LyaseThiolesteraseActivity',s("Catalysis","of","the","reaction",":","[","citrate","(","pro-3S",")","-lyase","]","(","acetyl","form",")","+","H2O","=","[","citrate","(","pro-3S",")","-lyase","]","(","thiol","form",")","+","acetate","."),4374041). assertion_content_comment('oboGo_CitrateReSynthaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","H2O","+","oxaloacetate","=","citrate","+","CoA",",","where","the","acetyl","group","is","added","to","the","re-face","of","oxaloacetate",";","acetyl-CoA","provides","the","two","carbon","atoms","of","the","pro-R","carboxymethyl","group","."),4267157). assertion_content_comment('oboGo_CitrateSiSynthaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","H2O","+","oxaloacetate","=","citrate","+","CoA",",","where","the","acetyl","group","is","added","to","the","si-face","of","oxaloacetate",";","acetyl-CoA","thus","provides","the","two","carbon","atoms","of","the","pro-S","carboxymethyl","group","."),4211949). assertion_content_comment('oboGo_CitronellylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","citronellyl-CoA","+","NAH","+","=","cis-geranyl-CoA","+","NADH","+","H","+"),4350584). assertion_content_comment('oboGo_CitronellylCoaligaseactivity',s("Catalysis","of","the","reaction",":","citronellate","+","CoASH","+","ATP","=","citronellyl-CoA","+","AMP","+","PPi","."),4350575). assertion_content_comment('oboGo_CitrylCoalyaseactivity',s("Catalysis","of","the","reaction",":","(","3S",")","-citryl-CoA","=","acetyl-CoA","+","oxaloacetate","."),4250738). assertion_content_comment('oboGo_ClassicalComplementPathwayc3c5convertaseactivity',s("OBSOLETE",".","Catalysis","of","the","selective","cleavage","of","Arg-Ser","bond","in","complement","component","C3","alpha-chain","to","form","C3a","and","C3b",",","and","Arg","bond","in","complement","component","C5","alpha-chain","to","form","C5a","and","C5b","."),4188203). assertion_content_comment('oboGo_ClassicalComplementPathwayc3c5convertasecomplex',s("A","heterodimeric","protein","complex","that","catalyzes","the","cleavage","of","complement","components","C3","and","C5",",","and","acts","in","the","classical","pathway","of","complement","activation",";","consists","of","one","monomer","of","C2a","and","one","monomer","of","C4b",";","C2a","is","the","catalytic","subunit",",","but","cannot","catalyze","cleavage","alone","."),4007173). assertion_content_comment('oboGo_ClathrinCoatedendocyticvesiclemembrane',s("The","lipid","bilayer","surrounding","a","clathrin-coated","endocytic","vesicle","."),4051694). assertion_content_comment('oboGo_ClathrinCoatedendocyticvesicle',s("A","clathrin-coated",",","membrane-bounded","intracellular","vesicle","formed","by","invagination","of","the","plasma","membrane","around","an","extracellular","substance","."),4051652). assertion_content_comment('oboGo_ClathrinCoatedphagocyticvesiclemembrane',s("The","lipid","bilayer","surrounding","a","clathrin-coated","phagocytic","vesicle","."),4051709). assertion_content_comment('oboGo_ClathrinCoatedphagocyticvesicle',s("A","clathrin-coated",",","membrane-bounded","intracellular","vesicle","that","arises","from","the","ingestion","of","particulate","material","by","phagocytosis","."),4051665). assertion_content_comment('oboGo_ClathrinCoatedvesicle',s("A","vesicle","with","a","coat","formed","of","clathrin","connected","to","the","membrane","via","one","of","the","clathrin","adaptor","complexes","."),4036133). assertion_content_comment('oboGo_ClathrinCoatingOfGolgiVesicleTransGolgitoendosometargeting',s("The","addition","of","clathrin","and","adaptor","proteins","to","Golgi","membranes","during","the","formation","of","transport","vesicles","that","will","move","from","the","trans-Golgi","to","the","endosome",",","forming","a","vesicle","coat","."),4025360). assertion_content_comment('oboGo_ClathrinCoatOfTransGolginetworkvesicle',s("A","clathrin","coat","found","on","a","vesicle","of","the","trans-Golgi","network","."),4053132). assertion_content_comment('oboGo_ClathrinMediatedendocytosis',s("An","endocytosis","process","that","begins","when","material","is","taken","up","into","clathrin-coated","pits",",","which","then","pinch","off","to","form","clathrin-coated","endocytic","vesicles","."),4142953). assertion_content_comment('oboGo_ClathrinSculptedGammaAminobutyricacidtransportvesiclelumen',s("The","volume","enclosed","by","the","membrane","of","the","clathrin","sculpted","gamma-aminobutyric","acid","transport","vesicle","."),4136011). assertion_content_comment('oboGo_ClathrinSculptedGammaAminobutyricacidtransportvesiclemembrane',s("The","lipid","bilayer","surrounding","a","clathrin","sculpted","gamma-aminobutyric","acid","transport","vesicle","."),4136230). assertion_content_comment('oboGo_ClathrinSculptedGammaAminobutyricacidtransportvesicle',s("A","clathrin","sculpted","lipid","bilayer","membrane-enclosed","vesicle","after","clathrin","release","and","containing","gamma-aminobutyric","acid","transport","vesicle","."),4136000). assertion_content_comment('oboGo_CleavageBetween2SRRNAAndLSURrnaoftetracistronicrrnatranscriptssuRrna58srrna2srrnalsuRrna',s("Endonucleolytic","cleavage","between","the","LSU-rRNA","and","the","2S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","2S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976415). assertion_content_comment('oboGo_CleavageBetween58SRRNAAnd2SRRNAOfTetracistronicRRNATranscriptSSURrna58srrna2srrnalsuRrna',s("Endonucleolytic","cleavage","between","the","5.8S","rRNA","and","the","2S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","2S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976395). assertion_content_comment('oboGo_CleavageBetweenSSURrnaand58srrnaoftetracistronicrrnatranscriptssuRrna58srrna2srrnalsuRrna',s("Endonucleolytic","cleavage","between","the","SSU-rRNA","and","the","5.8S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","2S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976435). assertion_content_comment('oboGo_CleavageInITS2Between58SRRNAAndLSURrnaoftricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","within","ITS2","between","the","5.8S","rRNA","and","the","LSU-rRNA","of","an","rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976646). assertion_content_comment('oboGo_CleavageOfBicistronicRRNATranscriptSSURrnalsuRrna',s("Endonucleolytic","cleavage","of","pre-rRNAs","originally","produced","as","a","bicistronic","rRNA","transcript","that","contains","the","SSU-rRNA","and","the","LSU-rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","Primary","ribosomal","RNA","transcripts","with","two","genes","in","this","order","are","produced","in","Archaeal","species","."),4362501). assertion_content_comment('oboGo_ClusteringOfVoltageGatedcalciumchannels',s("The","process","in","which","voltage-gated","calcium","channels","become","localized","together","in","high","densities","."),4180131). assertion_content_comment('oboGo_ClusteringOfVoltageGatedpotassiumchannels',s("The","process","in","which","voltage-gated","potassium","channels","become","localized","together","in","high","densities",".","In","animals",",","voltage-gated","potassium","(","Kv",")","channels","are","clustered","beneath","the","myelin","sheath","in","regions","immediately","adjacent","to","paranodes",",","called","juxtaparanodes",",","and","along","the","inner","mesaxon","within","the","internode","."),4300323). assertion_content_comment('oboGo_ClusteringOfVoltageGatedsodiumchannels',s("The","process","in","which","voltage-gated","sodium","channels","become","localized","together","in","high","densities",".","In","animals",",","nodes","of","Ranvier","differ","dramatically","from","internodal","axonal","regions","in","very","high","densities","of","voltage-dependent","sodium","(","Nav",")","channels","responsible","for","the","rapid",",","inward","ionic","currents","that","produce","membrane","depolarization","."),4300336). assertion_content_comment('oboGo_ClypeoLabraldiscdevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","clypeo-labral","disc","over","time",",","from","its","formation","to","the","metamorphosis","to","form","adult","structures",".","The","clypeo-labral","disc","develops","into","the","labrum",",","anterior","cibarial","plate",",","fish","trap","bristles",",","epistomal","sclerite","."),4017716). assertion_content_comment('oboGo_ClypeoLabraldiscmorphogenesis',s("The","process","in","which","the","anatomical","structures","derived","from","the","clypeo-labral","disc","are","generated","and","organized",".","This","includes","the","transformation","of","a","clypeo-labal","imaginal","disc","from","a","monolayered","epithelium","in","the","larvae","of","holometabolous","insects","into","recognizable","adult","structures","including","the","labrum",",","anterior","and","posterior","cibarial","plates",",","fish","trap","bristles",",","epistomal","sclerite","and","clypeus","."),4017727). assertion_content_comment('oboGo_CMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","to","the","carbon","atom","of","an","acceptor","molecule","."),4180531). assertion_content_comment('oboGo_CMP_Keto_3_Deoxy_D_Manno_OctulosonicAcidBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","CMP-keto-3-deoxy-D-manno-octulosonic","acid",",","a","substance","composed","of","the","acidic","sugar","3-deoxy-D-manno-octulosonic","acid","in","glycosidic","linkage","with","cytidine","monophosphate","."),4339553). assertion_content_comment('oboGo_CMP_Keto_3_Deoxy_D_Manno_OctulosonicAcidMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","CMP-keto-3-deoxy-D-manno-octulosonic","acid",",","a","substance","composed","of","the","acidic","sugar","3-deoxy-D-manno-octulosonic","acid","in","glycosidic","linkage","with","cytidine","monophosphate","."),4339538). assertion_content_comment('oboGo_CMPNAcetylneuraminatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","CMP-N-acetylneuraminate",",","a","substance","composed","of","5-","(","acetylamino",")","-3",",","5-dideoxy-D-glycero-D-galacto-non-3-ulosonic","acid","in","glycosidic","linkage","with","cytidine","monophosphate","."),4224756). assertion_content_comment('oboGo_CMPNAcetylneuraminatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","CMP-N-acetylneuraminate",",","a","substance","composed","of","5-","(","acetylamino",")","-3",",","5-dideoxy-D-glycero-D-galacto-non-3-ulosonic","acid","in","glycosidic","linkage","with","cytidine","monophosphate","."),4224753). assertion_content_comment('oboGo_CMPNAcetylneuraminatemonooxygenaseactivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","NADPH","+","H","+","+","O2","=","CMP-N-glycoloylneuraminate","+","NADP","+","+","H2O","."),4309598). assertion_content_comment('oboGo_CMPNAcetylneuraminatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","CMP-N-acetylneuraminate","from","one","side","of","the","membrane","to","the","other","."),4219464). assertion_content_comment('oboGo_CMPNAcetylneuraminatetransport',s("The","directed","movement","of","CMP-N-acetylneuraminate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4291292). assertion_content_comment('oboGo_CMPNAcylneuraminatephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","H2O","+","CMP-N-acylneuraminate","=","N-acylneuraminate","+","CMP","."),4368495). assertion_content_comment('oboGo_CoADisulfidereductaseactivity',s("Catalysis","of","the","reaction",":","2","CoA","+","NAD","+","=","CoA-disulfide","+","NADH","+","H","+"),4267187). assertion_content_comment('oboGo_CoAGlutathionereductaseactivity',s("Catalysis","of","the","reaction",":","CoA","+","glutathione","+","NADP","+","=","CoA-glutathione","+","NADPH","+","H","+"),4267171). assertion_content_comment('oboGo_CoALigaseactivity',s("Catalysis","of","the","reaction",":","substrate","+","ATP","+","CoASH","=","AMP","+","diphosphate","+","substrate-CoA","."),4186268). assertion_content_comment('oboGo_CoATransferaseactivity',s("Catalysis","of","the","transfer","of","a","coenzyme","A","(","CoA",")","group","from","one","compound","(","donor",")","to","another","(","acceptor",")"),4250777). assertion_content_comment('oboGo_Cobalamin5Phosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","adenosylcobinamide-GDP","+","alpha-ribazole-5","'","-phosphate","=","adenosylcobalamin-5","'","-phosphate","+","GMP","."),4250287). assertion_content_comment('oboGo_CobalaminTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","cob","(","III",")","alamin","(","out",")","=","ADP","+","phosphate","+","cob","(","III",")","alamin","(","in",")","Cobalamin","is","also","known","as","vitamin","B12","."),4291635). assertion_content_comment('oboGo_CobaltFactoriic20Methyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","cobalt-factor","II","=","S-adenosyl-L-homocysteine","+","cobalt-factor","III","."),4327810). assertion_content_comment('oboGo_Cobalt_Precorrin_3C17_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","cobalt-precorrin","3","+","S-adenosyl-L-methionine","=","cobalt-precorrin","4","+","S-adenosyl-L-homocysteine","."),4327796). assertion_content_comment('oboGo_Cobalt_Precorrin_5AAcetaldehyde_LyaseActivity',s("Catalysis","of","the","reaction",":","cobalt-precorrin","5A","+","H2O","=","cobalt-precorrin","5B","+","acetaldehyde","."),4327757). assertion_content_comment('oboGo_Cobalt_Precorrin_5BC1_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","cobalt-precorrin","5B","+","S-adenosylmethionine","=","S-adenosylhomocysteine","+","cobalt-precorrin","6A","."),4327824). assertion_content_comment('oboGo_Cobalt_Precorrin_6BC5_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","S-adenosylmethionine","+","cobalt-precorrin","6B","=","S-adenosylhomocysteine","+","cobalt-precorrin","7","."),4327768). assertion_content_comment('oboGo_Cobalt_Precorrin_7C15_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","cobalt-precorrin","7","+","S-adenosyl-L-methionine","=","cobalt-precorrin","8","+","S-adenosyl-L-homocysteine","+","CO2","."),4327782). assertion_content_comment('oboGo_Cobalt_Precorrin_8MethylmutaseActivity',s("Catalysis","of","the","reaction",":","cobalt-precorrin","8","=","cobyrinate","."),4327744). assertion_content_comment('oboGo_CobaltTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","cobalt","(","out",")","=","ADP","+","phosphate","+","cobalt","(","in",")"),4337562). assertion_content_comment('oboGo_CoBComheterodisulfidereductaseactivity',s("Catalysis","of","the","reaction",":","coenzyme","B","+","coenzyme","M","+","methanophenazine","=","N-","{","7-","[","(","2-sulfoethyl",")","dithio","]","heptanoyl","}","-3-O-phospho-L-threonine","+","dihydromethanophenazine","."),4183220). assertion_content_comment('oboGo_CobIIYrinicAcidACDiamidereductaseactivity',s("Catalysis","of","the","reaction",":","2","cob","(","I",")","yrinate","a",",","c","diamide","+","FMN","+","3","H","(","+",")","=","2","cob","(","II",")","yrinate","a",",","c","diamide","+","FMNH","(","2",")"),4327867). assertion_content_comment('oboGo_CobIYrinicAcidACDiamideadenosyltransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","cob","(","I",")","alamin","+","H2O","=","phosphate","+","diphosphate","+","adenosylcobalamin","."),4250750). assertion_content_comment('oboGo_CobyrinateACDiamidesynthaseactivity',s("Catalysis","of","the","reaction",":","cobyrinate","+","2","L-glutamine","+","2","ATP","+","2","H2O","=","cob","(","II",")","yrinate","a",",","c-diamide","+","2","L-glutamate","+","2","ADP","+","2","orthophosphate","."),4327989). assertion_content_comment('oboGo_CobyrinicAcidACDiamidesynthaseactivity',s("Catalysis","of","the","conversion","of","cobyrinic","acid","to","cobyrinic","acid","a",",","c-diamide","via","the","intermediate","formation","of","cobyrinic","acid","c-monoamide","."),4314675). assertion_content_comment('oboGo_CoChaperoneactivity',s("OBSOLETE",".","Co-chaperones","are","proteins","that","bind","to","chaperones","and","this","complex","then","folds","misfolded","proteins",".","Co-chaperones","by","themselves","do","not","possess","chaperone","activity","."),4192360). assertion_content_comment('oboGo_CoChaperoninactivity',s("OBSOLETE",".","Co-chaperonins","are","proteins","that","bind","to","chaperones","and","this","complex","then","folds","misfolded","proteins",".","Co-chaperonins","by","themselves","do","not","possess","chaperone","activity","."),4193100). assertion_content_comment('oboGo_CoenzymeAPeptidylCysteinecovalentlinking',s("The","covalent","linkage","of","coenzyme","A","and","peptidyl-cysteine","to","form","L-cysteine","coenzyme","A","disulfide","."),4245659). assertion_content_comment('oboGo_CoenzymeBsulfoethylthiotransferaseactivity',s("Catalysis","of","the","reaction",":","coenzyme","B","+","methyl-coenzyme","M","=","coenzyme","M-coenzyme","B","heterodisulfide","+","methane",".","Methyl-CoM","is","also","known","as","2-","(","methylthio",")","ethanesulfonate",",","coenzyme","B","as","N-","(","7-mercaptoheptanoyl",")","threonine","3-O-phosphate",",","and","coenzyme","M-coenzyme","B","heterodisulfide","as","CoM-S-S-CoB","."),4269348). assertion_content_comment('oboGo_CoenzymeF4200gammaGlutamylligaseactivity',s("Catalysis","of","the","reactions",":","(","1",")","GTP","+","F420-0","+","L-glutamate","=","GDP","+","phosphate","+","F420-1",",","and","(","2",")","GTP","+","F420-1","+","L-glutamate","=","GDP","+","phosphate","+","gamma-F420-2",".","This","is","the","GTP-dependent","successive","addition","of","two","L-glutamates","to","the","L-lactyl","phosphodiester","of","7",",","8-didemethyl-8-hydroxy-5-deazariboflavin","(","F420-0",")","to","form","F420-0-glutamyl-glutamate","(","F420-2",")",",","with","a","gamma-linkage","between","the","two","glutamates","."),4327965). assertion_content_comment('oboGo_CoenzymeF4200_LGlutamateligaseactivity',s("Catalysis","of","the","reaction",":","GTP","+","L-glutamate","+","factor","F420-0","=","GDP","+","H","+","+","factor","gamma-F420-1","+","phosphate","."),4191049). assertion_content_comment('oboGo_CoenzymeF420_1_Gamma_L_GlutamateLigaseActivity',s("Catalysis","of","the","reaction",":","GTP","+","L-glutamate","+","factor","gamma-F420-1","=","GDP","+","H","+","+","factor","gamma-F420-2","+","phosphate","."),4191058). assertion_content_comment('oboGo_CoenzymeF420_2Alpha_GlutamylLigaseActivity',s("Catalysis","of","the","reaction",":","coenzyme","F420-2","+","L-glutamate","+","GTP","=","coenzyme","F420-3","+","GDP","+","orthophosphate","."),4328002). assertion_content_comment('oboGo_CoenzymeF420Dependentn5n10Methenyltetrahydromethanopterinreductaseactivity',s("Catalysis","of","the","reaction",":","5-methyltetrahydromethanopterin","+","coenzyme","F420","+","H","(","+",")","=","5",",","10-methylenetetrahydromethanopterin","+","reduced","coenzyme","F","(","420",")"),4278186). assertion_content_comment('oboGo_CoenzymeGamma_F420_2MetabolicProcess',s("The","chemical","reactions","and","pathways","involving","coenzyme","gamma-F420-2","(","F420-2",";","coenzyme","F420",";","N-","{","N-","[","O-","(","7",",","8-didemethyl-8-hydroxy-5-deazariboflavin","phospho",")","-","(","S",")","-lactyl","]","-gamma-L-glutamyl","}","-L-glutamate",")",",","the","amide","obtained","by","formal","condensation","of","the","carboxylic","acid","group","of","F420-0","with","the","amino","group","of","L-gamma-glutamyl-L-glutamic","acid","."),4191715). assertion_content_comment('oboGo_Coenzyme_M_7_Mercaptoheptanoylthreonine_Phosphate_HeterodisulfideHydrogenaseActivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","coenzyme-M","7-mercaptoheptanoylthreonine-phosphate","heterodisulfide","+","H2","=","coenzyme-M","+","N-","(","7-mercaptoheptanoyl",")","threonine","O3-phosphate","."),4298635). assertion_content_comment('oboGo_Collagen_8',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4217741). assertion_content_comment('oboGo_CollagenAndCuticulinBasedcuticleattachmenttoepithelium',s("Attaching","of","a","collagen","and","cuticulin-based","cuticle","to","the","epithelium","underlying","it",".","An","example","of","this","process","is","found","in","Caenorhabditis","elegans","."),4081721). assertion_content_comment('oboGo_CollagenAndCuticulinBasedcuticledevelopment',s("Synthesis","and","deposition","of","a","collagen","and","cuticulin-based","noncellular",",","hardened",",","or","membranous","secretion","from","an","epithelial","sheet",".","An","example","of","this","process","is","found","in","Caenorhabditis","elegans","."),4079612). assertion_content_comment('oboGo_CollagenAndCuticulinBasedcuticleextracellularmatrixpart',s("Any","constituent","part","of","the","collagen","and","cuticulin-based","cuticle","extracellular","matrix",",","a","collagen","and","cuticulin-based","noncellular",",","multilayered","structure","that","is","synthesized","by","an","underlying","ectodermal","(","hypodermal",")","cell","layer","."),4108844). assertion_content_comment('oboGo_CollagenAndCuticulinBasedcuticleextracellularmatrix',s("A","collagen","and","cuticulin-based","noncellular",",","multilayered","structure","that","is","synthesized","by","an","underlying","ectodermal","(","hypodermal",")","cell","layer",".","The","cuticle","serves","essential","functions","in","body","morphology",",","locomotion",",","and","environmental","protection",".","An","example","of","this","component","is","found","in","Caenorhabditis","elegans","."),4108826). assertion_content_comment('oboGo_ColumbamineOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","columbamine","=","S-adenosyl-L-homocysteine","+","H","(","+",")","+","palmatine","."),4309135). assertion_content_comment('oboGo_COMethylatingacetylCoasynthaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","corrinoid","protein","=","CO","+","methylcorrinoid","protein","+","CoA","."),4326761). assertion_content_comment('oboGo_CommaShapedbodymorphogenesis',s("The","process","in","which","the","comma-shaped","body","is","generated","and","organized",".","The","comma-shaped","body","is","the","precursor","structure","to","the","S-shaped","body","that","contributes","to","the","morphogenesis","of","the","nephron","."),4123657). assertion_content_comment('oboGo_CommonPartnersmadproteinphosphorylation',s("The","process","of","introducing","a","phosphate","group","on","to","a","common-partner","SMAD","protein",".","A","common","partner","SMAD","protein","binds","to","pathway-restricted","SMAD","proteins","forming","a","complex","that","translocates","to","the","nucleus","."),4017171). assertion_content_comment('oboGo_CommonPartnersmadprotein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4215403). assertion_content_comment('oboGo_CompatiblePollenPistilinteraction',s("OBSOLETE",".","An","interaction","between","a","pollen","grain","and","pistil","that","results","in","unimpeded","growth","of","the","pollen","tube","through","the","stigma","and","style","."),4262660). assertion_content_comment('oboGo_ConiferinBetaGlucosidaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","coniferin","=","D-glucose","+","coniferol","."),4373960). assertion_content_comment('oboGo_ConiferylAlcoholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","coniferyl","alcohol","+","NADP","+","=","coniferyl","aldehyde","+","NADPH","."),4263939). assertion_content_comment('oboGo_ConiferylAlcoholglucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","coniferyl","alcohol","+","UDP-D-glucose","=","coniferin","+","UDP","."),4366616). assertion_content_comment('oboGo_ConiferylAldehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","coniferyl","aldehyde","+","H2O","+","NAD","(","P",")","+","=","ferulate","+","NAD","(","P",")","H","+","H","+"),4263950). assertion_content_comment('oboGo_ConnectingHemiAdherensjunction',s("A","cell-substrate","adherens","junction",",","also","known","as","a","hemiadherens","junction","(","HAJ",")","that","forms","one","of","a","pair","of","junctions","in","opposing","cells","that","are","separated","by","only","30-40nm",",","with","a","thin","line","of","extracellular","electron-dense","material","in","between",";","found","where","muscles","attach","to","epidermal","cells","directly","(","in","insects",")"),4220696). assertion_content_comment('oboGo_ConvergentExtensionInvolvedInImaginalDiscDerivedwingmorphogenesis',s("The","morphogenetic","process","in","which","the","wing","epithelium","narrows","along","one","axis","and","lengthens","in","a","perpendicular","axis","that","contributes","to","imaginal","disc-derived","wing","morphogenesis","."),4151982). assertion_content_comment('oboGo_ConversionOfAspartylTrnatoasparaginylTrna',s("The","modification","process","that","results","in","the","conversion","of","aspartate","charged","on","a","tRNA","(","Asn",")","to","asparaginyl-tRNA","."),4326363). assertion_content_comment('oboGo_ConversionOfDiscoidalHighDensitylipoproteinparticletosphericalhighDensitylipoproteinparticle',s("The","process","in","which","a","discoidal","high-density","lipoprotein","(","HDL",")","particle","acquires","additional","lipid","or","protein","molecules",",","and","cholesterol","in","the","particle","is","converted","to","tightly","bound","cholesterol","esters","by","the","action","of","phosphatidylcholine-sterol","O-acyltransferase","(","lecithin","cholesterol","acyltransferase",";","LCAT",")",",","resulting","in","the","formation","of","a","spherical","HDL","particle","."),4355617). assertion_content_comment('oboGo_ConversionOfGlutamylTrnatoglutaminylTrna',s("The","modification","process","that","results","in","the","conversion","of","glutamate","charged","on","a","tRNA","(","Gln",")","to","glutaminyl-tRNA","."),4326507). assertion_content_comment('oboGo_ConversionOfLysylTrnatopyrrolysylTrna',s("The","modification","process","that","results","in","the","conversion","of","lysine",",","carried","by","a","specialized","lysine-accepting","tRNA","(","possessing","a","CUA","anticodon",")",",","to","pyrrolysine","(","a","lysine","with","an","amide","linkage","to","a","(","4R",",","5R",")","-4-substituted","pyrroline-5-carboxylate",")"),4383293). assertion_content_comment('oboGo_ConversionOfMethionylTrnatonFormylMethionylTrna',s("The","modification","process","that","results","in","the","conversion","of","methionine","charged","on","a","tRNA","(","fMet",")","to","N-formyl-methionine-tRNA","(","fMet",")"),4168792). assertion_content_comment('oboGo_ConversionOfOPhosphoserylTrnatocysteinylTrna',s("The","modification","process","that","results","in","the","conversion","of","O-phosphoserine","charged","on","a","tRNA","(","Cys",")","to","cysteinyl-tRNA","."),4168803). assertion_content_comment('oboGo_ConversionOfSerylTrnasectoselenocysTrnasec',s("The","modification","process","that","results","in","the","conversion","of","serine",",","carried","by","a","specialized","tRNA","(","ser",")","(","which","can","read","a","UGA","anticodon",")",",","to","selenocysteine","."),4383326). assertion_content_comment('oboGo_COPICoatedvesicle',s("A","vesicle","with","a","coat","formed","of","the","COPI","coat","complex","proteins",".","COPI-coated","vesicles","are","found","associated","with","Golgi","membranes","at","steady","state",",","are","involved","in","Golgi","to","endoplasmic","reticulum","(","retrograde",")","vesicle","transport",",","and","possibly","also","in","intra-Golgi","transport","."),4035998). assertion_content_comment('oboGo_COPICoatingOfGolgiVesicleCisGolgitorougher',s("The","addition","of","COPI","proteins","and","adaptor","proteins","to","Golgi","membranes","during","the","formation","of","cis-Golgi","to","rough","ER","transport","vesicles",",","forming","a","vesicle","coat","."),4025431). assertion_content_comment('oboGo_COPICoatingOfGolgiVesicleInterGolgicisterna',s("The","addition","of","COPI","proteins","and","adaptor","proteins","to","Golgi","membranes","during","the","formation","of","inter-Golgi","cisterna","transport","vesicles",",","forming","a","vesicle","coat","."),4025462). assertion_content_comment('oboGo_COPIICoatedvesiclebudding',s("The","evagination","of","an","endoplasmic","reticulum","membrane",",","resulting","in","formation","of","a","COPII","vesicle","."),4004944). assertion_content_comment('oboGo_CopperDependentproteinbinding',s("Interacting","selectively","and","non-covalently","with","any","protein","or","protein","complex","(","a","complex","of","two","or","more","proteins","that","may","include","other","nonprotein","molecules",")",",","in","the","presence","of","copper","."),4337471). assertion_content_comment('oboGo_Copper_ExportingATPaseActivity_7',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4331019). assertion_content_comment('oboGo_CopperExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Cu2","+","(","in",")","=","ADP","+","phosphate","+","Cu2","+","(","out",")"),4212944). assertion_content_comment('oboGo_CopperIncorporationIntoCopperSulfurcluster',s("The","incorporation","of","copper","into","a","copper-sulfur","cluster","."),4281900). assertion_content_comment('oboGo_CopperIncorporationIntoCopperSulfurclusterviaheptakisLHistidinotetracoppermu4Sulfidehydroxide',s("The","incorporation","of","copper","into","a","4Cu-S","copper-sulfur","cluster","via","heptakis-L-histidino","tetracopper","mu4-sulfide","hydroxide","."),4281903). assertion_content_comment('oboGo_CopperIncorporationIntoMetalloSulfurcluster',s("The","incorporation","of","copper","into","a","metallo-sulfur","cluster","."),4274701). assertion_content_comment('oboGo_CopperIncorporationViaLCysteinylcoppersulfidomolybdopterincytosinedinucleotide',s("The","incorporation","of","copper","into","a","protein","by","L-cysteinyl","copper","sulfido","molybdopterin","cytosine","dinucleotide","."),4274704). assertion_content_comment('oboGo_CopperInducedintracellularproteintransport',s("The","directed","movement","of","proteins","in","a","cell",",","including","the","movement","of","proteins","between","specific","compartments","or","structures","within","a","cell",",","such","as","organelles","of","a","eukaryotic","cell",",","induced","by","an","increase","in","copper","ion","concentration","."),4337551). assertion_content_comment('oboGo_CopperNicotianaminetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","the","copper","chelate","copper-nicotianamine","(","Cu-NA",")","from","one","side","of","a","membrane","to","the","other","."),4183419). assertion_content_comment('oboGo_CopperTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Cu2","+","=","ADP","+","phosphate","+","Cu2","+",",","directly","driving","the","transport","of","the","copper","ions","across","a","membrane","."),4212942). assertion_content_comment('oboGo_CoreBindingfactorcomplex',s("A","heterodimeric","transcription","factor","complex","that","contains","an","alpha","subunit","(","Runx1",",","Runx2","or","Runx3","in","human",")","that","binds","DNA","and","a","non-DNA-binding","beta","subunit","(","CBFbeta",")",",","and","binds","to","a","consensus","sequence","5","'","-YGYGGTY-3","'","found","in","several","enhancers","and","promoters",";","the","beta","subunit","enhances","the","DNA","binding","of","the","alpha","subunit","."),4305383). assertion_content_comment('oboGo_CorePromoterProximalRegionSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","the","core","promoter",".","The","transcribed","region","might","be","described","as","a","gene",",","cistron",",","or","operon","."),4356394). assertion_content_comment('oboGo_CorePromoterSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","part","of","a","core","promoter","region","composed","of","the","transcription","start","site","and","binding","sites","for","the","basal","transcription","machinery",".","The","transcribed","region","might","be","described","as","a","gene",",","cistron",",","or","operon","."),4356347). assertion_content_comment('oboGo_CorneaDevelopmentInCameraTypeeye',s("The","progression","of","the","cornea","over","time",",","from","its","formation","to","the","mature","structure",".","The","cornea","is","the","transparent","structure","that","covers","the","anterior","of","the","eye","."),4134830). assertion_content_comment('oboGo_CorticalLayerOfCollagenAndCuticulinBasedcuticleextracellularmatrix',s("The","cuticle","layer","that","lies","directly","beneath","the","lipid-containing","epicuticle",".","The","cortical","layer","contains","collagens","and","insoluble",",","non-collagenous","cuticulins","and","is","characterized","by","a","distinct","annular","pattern","consisting","of","regularly","spaced","annular","ridges","delineated","by","annular","furrows",".","An","example","of","this","component","is","found","in","Caenorhabditis","elegans","."),4108858). assertion_content_comment('oboGo_CorticosteroidSideChainIsomeraseactivity',s("Catalysis","of","the","reaction",":","11-deoxycorticosterone","=","20-hydroxy-3-oxopregn-4-en-21-al","."),4212012). assertion_content_comment('oboGo_Corticosterone18Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","corticosterone","+","reduced","adrenal","ferredoxin","+","O2","=","18-hydroxycorticosterone","+","oxidized","adrenal","ferredoxin","+","H2O","."),4373948). assertion_content_comment('oboGo_CorticotrophinReleasingfactorgastricinhibitorypeptideLikereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383981). assertion_content_comment('oboGo_CorticotrophinReleasingfactorreceptoractivity',s("Combining","with","the","corticotrophin-releasing","factor","family","of","ligands",",","including","the","urocortins",",","to","initiate","a","change","in","cell","activity","."),4297212). assertion_content_comment('oboGo_CorticotropinReleasinghormoneactivity',s("The","action","characteristic","of","corticotropin-releasing","hormone","(","CRH",")",",","any","of","a","number","of","peptides","released","by","the","mammalian","hypothalamus","into","the","hypophyseal-portal","circulation","in","response","to","neural","and/or","chemical","stimuli",".","Upon","receptor","binding",",","CRH","increases","the","rate","of","corticotropin","secretion","by","the","anterior","pituitary","."),4268270). assertion_content_comment('oboGo_CorticotropinReleasinghormonebinding',s("Interacting","selectively","and","non-covalently","with","corticotropin-releasing","hormone",",","a","polypeptide","hormone","involved","in","the","stress","response",".","It","is","released","by","the","hypothalamus","and","stimulates","the","release","of","corticotropin","by","the","anterior","pituitary","gland","."),4286753). assertion_content_comment('oboGo_CorticotropinReleasinghormonereceptor1binding',s("Interacting","selectively","and","non-covalently","with","the","corticotropin-releasing","hormone","receptor","1","(","CRHR1",")","CRHR1","is","the","major","subtype","in","the","pituitary","corticotroph",",","and","mediates","the","stimulatory","actions","of","corticotropin-releasing","hormone","on","corticotropin","hormone","secretion",".","CRHR1","are","also","located","in","cortical","areas","of","the","brain",",","cerebellum","and","limbic","system","."),4286684). assertion_content_comment('oboGo_CorticotropinReleasinghormonereceptor2binding',s("Interacting","selectively","and","non-covalently","with","the","corticotropin-releasing","hormone","receptor","type","2","(","CRHR2",")","The","CRHR2","has","several","splice","variants","that","are","located","in","sub-cortical","areas","of","the","brain","and","in","the","periphery","."),4286670). assertion_content_comment('oboGo_CorticotropinReleasinghormonereceptoractivity',s("Combining","with","corticotropin-releasing","hormone","to","initiate","a","change","in","cell","activity","."),4324779). assertion_content_comment('oboGo_CorticotropinReleasinghormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","receptor","for","corticotropin-releasing","hormone","(","CRH",")",",","a","polypeptide","hormone","involved","in","the","stress","response",".","It","is","released","by","the","hypothalamus","and","stimulates","the","release","of","corticotropin","by","the","anterior","pituitary","gland","."),4286662). assertion_content_comment('oboGo_CorticotropinReleasinghormonesecretion',s("The","regulated","release","of","corticotropin-releasing","hormone","(","CRH",")",",","a","polypeptide","hormone","involved","in","the","stress","response",".","CRH","is","produced","by","the","hypothalamus","and","stimulates","corticotropic","cells","of","the","anterior","lobe","of","the","pituitary","to","produce","corticotropic","hormone","(","CTH",")","and","other","biologically","active","substances","e.g",".","2-endorphin",",","release","of","CRH","is","affected","by","serum","levels","of","cortisol",",","by","stress","and","by","the","sleep/wake","cycle","."),4095769). assertion_content_comment('oboGo_CortisolOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","cortisol","=","CoA","+","cortisol","21-acetate","."),4373935). assertion_content_comment('oboGo_CortisoneAlphaReductaseactivity',s("Catalysis","of","the","reaction",":","4",",","5alpha-dihydrocortisone","+","NADP","(","+",")","=","cortisone","+","H","(","+",")","+","NADPH","."),4373884). assertion_content_comment('oboGo_CoSmadbinding',s("Interacting","selectively","and","non-covalently","with","a","common","mediator","SMAD","signaling","protein","."),4175492). assertion_content_comment('oboGo_CoTranslationalproteinacetylation',s("The","addition","of","an","acetyl","group","to","one","or","more","amino","acids","in","a","protein",",","occurring","before","the","protein","has","been","completely","translated","and","released","from","the","ribosome","."),4357360). assertion_content_comment('oboGo_CoTranslationalproteinmodification',s("The","process","of","covalently","altering","one","or","more","amino","acids","in","a","protein","after","translation","has","begun","but","before","the","protein","has","been","released","from","the","ribosome","."),4326491). assertion_content_comment('oboGo_CoTranslationalproteintagging',s("A","protein","modification","process","in","which","a","polypeptide","is","added","to","a","nascent","polypeptide","cotranslationally","by","trans-translation","."),4177906). assertion_content_comment('oboGo_Coumarin7Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","coumarin","+","O2","+","NADPH","+","H","+","=","hydroxycoumarin","+","H2O","+","NADP","+"),4255565). assertion_content_comment('oboGo_CP2MannoseEthanolaminephosphotransferaseactivity',s("Catalysis","of","the","reaction",":","ethanolamine","phosphate","+","Man-alpha-","(","1",",","2",")","-Man-alpha-","(","1",",","2",")","-Man-alpha-","(","1",",","6",")","-R","=","Man-alpha-","(","1",",","2",")","-Man-alpha-6-P-EtN-","(","1",",","2",")","-Man-alpha-","(","1",",","6",")","-R",";","R","is","Man-alpha","(","1",",","4",")","-GlcNH2-inositol-PO4-lipid",".","This","reaction","is","the","transfer","of","ethanolamine","phosphate","to","C6","of","second","mannose","in","the","GPI","lipid","precursor","CP2","."),4285763). assertion_content_comment('oboGo_CPalmitoyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","palmitoyl","group","to","a","carbon","atom","on","the","acceptor","molecule","."),4201524). assertion_content_comment('oboGo_CRDMediatedmrnastabilitycomplex',s("A","protein","complex","that","binds","to",",","and","promotes","stabilization","of",",","mRNA","molecules","containing","the","coding","region","instability","determinant","(","CRD",")","In","human",",","IGF2BP1","and","at","least","four","additional","proteins",":","HNRNPU",",","SYNCRIP",",","YBX1",",","and","DHX9","."),4177979). assertion_content_comment('oboGo_CRDMediatedmrnastabilization',s("An","mRNA","stabilization","process","in","which","one","or","more","RNA-binding","proteins","associate","with","a","sequence","in","the","open","reading","frame","called","the","coding","region","instability","determinant","(","CRD",")"),4177947). assertion_content_comment('oboGo_CrossedFormFourWayjunctiondnabinding',s("Interacting","selectively","and","non-covalently","with","DNA","containing","the","crossed","form","of","a","four-way","junction",",","also","known","as","a","Holliday","junction",",","a","structure","where","two","DNA","double","strands","are","held","together","by","reciprocal","exchange","of","two","of","the","four","strands",",","one","strand","each","from","the","two","original","helices",".","The","crossed","form","of","a","four-way","junction","cannot","be","diagrammed","without","any","of","the","strands","crossing","over",",","and","instead","contains","a","single","crossover","between","two","of","the","strands","."),4362768). assertion_content_comment('oboGo_CrotonobetaineCarnitineCoaligaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4250229). assertion_content_comment('oboGo_CrotonobetaineCoaligaseactivity',s("Catalysis","of","the","reaction",":","CoA","+","crotono-betaine","+","ATP","=","AMP","+","diphosphate","+","crotonobetainyl-CoA","."),4250224). assertion_content_comment('oboGo_CrotonoylAcylCarrierProteinhydrataseactivity',s("Catalysis","of","the","reaction",":","(","3R",")","-3-hydroxybutanoyl-","[","acyl-carrier","protein","]","=","H2O","+","but-2-enoyl-","[","acyl-carrier","protein","]"),4369457). assertion_content_comment('oboGo_CrotonylCoareductaseactivity',s("Catalysis","of","the","reduction","of","crotonyl-CoA","to","butyryl-CoA","."),4326700). assertion_content_comment('oboGo_CSKGapAp62complex',s("A","protein","complex","that","contains","the","protein-tyrosine","kinase","CSK","and","the","GTPase-activating","protein","(","GAP",")","-associated","p62","(","GAP-A.p62",")",";","may","mediate","translocation","of","proteins",",","including","GAP","and","CSK",",","to","membrane","or","cytoskeletal","regions","upon","c-Src","activation","."),4137371). assertion_content_comment('oboGo_CTerminalpeptidylAlanineamidation',s("The","formation","of","a","C-terminal","peptidyl-alanine","amide","by","hydrolysis","and","oxidation","of","an","interior","Ala-Gly","peptide","in","a","secreted","protein","."),4282977). assertion_content_comment('oboGo_CTerminalpeptidylArginineamidation',s("The","formation","of","a","C-terminal","peptidyl-arginine","amide","by","hydrolysis","and","oxidation","of","an","interior","Arg-Gly","peptide","in","a","secreted","protein","."),4282935). assertion_content_comment('oboGo_CTerminalpeptidylAsparagineamidation',s("The","formation","of","a","C-terminal","peptidyl-asparagine","amide","by","hydrolysis","and","oxidation","of","an","interior","Asn-Gly","peptide","in","a","secreted","protein","."),4282924). assertion_content_comment('oboGo_CTerminalpeptidylAsparticacidamidation',s("The","formation","of","a","C-terminal","peptidyl-aspartic","acid","1-amide","by","hydrolysis","and","oxidation","of","an","interior","Asp-Gly","peptide","in","a","secreted","protein","."),4282957). assertion_content_comment('oboGo_CTerminalpeptidylCysteineamidation',s("The","formation","of","a","C-terminal","peptidyl-cysteine","amide","by","hydrolysis","and","oxidation","of","an","interior","Cys-Gly","peptide","in","a","secreted","protein","."),4282946). assertion_content_comment('oboGo_CTerminalpeptidylGlutamicacidamidation',s("The","formation","of","a","C-terminal","peptidyl-glutamic","acid","amide","by","hydrolysis","and","oxidation","of","an","interior","Glu-Gly","peptide","in","a","secreted","protein","."),4283306). assertion_content_comment('oboGo_CTerminalpeptidylGlutamicacidtyrosinylation',s("The","ATP-dependent","addition","of","a","tyrosine","residue","to","a","glutamic","acid","residue","at","the","C-terminus","of","a","protein","."),4282623). assertion_content_comment('oboGo_CTerminalpeptidylGlutamineamidation',s("The","formation","of","a","C-terminal","peptidyl-glutamine","amide","by","hydrolysis","and","oxidation","of","an","interior","Gln-Gly","peptide","in","a","secreted","protein","."),4282913). assertion_content_comment('oboGo_CTerminalpeptidylGlycineamidation',s("The","formation","of","a","C-terminal","peptidyl-glycine","acid","amide","by","hydrolysis","and","oxidation","of","an","interior","Gly-Gly","peptide","in","a","secreted","protein","."),4283317). assertion_content_comment('oboGo_CTerminalpeptidylHistidineamidation',s("The","formation","of","a","C-terminal","peptidyl-histidine","amide","by","hydrolysis","and","oxidation","of","an","interior","His-Gly","peptide","in","a","secreted","protein","."),4283252). assertion_content_comment('oboGo_CTerminalpeptidylIsoleucineamidation',s("The","formation","of","a","C-terminal","peptidyl-isoleucine","amide","by","hydrolysis","and","oxidation","of","an","interior","Ile-Gly","peptide","in","a","secreted","protein","."),4283241). assertion_content_comment('oboGo_CTerminalpeptidylLeucineamidation',s("The","formation","of","a","C-terminal","peptidyl-leucine","amide","by","hydrolysis","and","oxidation","of","an","interior","Leu-Gly","peptide","in","a","secreted","protein","."),4283230). assertion_content_comment('oboGo_CTerminalpeptidylLysineamidation',s("The","formation","of","a","C-terminal","peptidyl-lysine","amide","by","hydrolysis","and","oxidation","of","an","interior","Lys-Gly","peptide","in","a","secreted","protein","."),4283209). assertion_content_comment('oboGo_CTerminalpeptidylMethionineamidation',s("The","formation","of","a","C-terminal","peptidyl-methionine","amide","by","hydrolysis","and","oxidation","of","an","interior","Met-Gly","peptide","in","a","secreted","protein","."),4283296). assertion_content_comment('oboGo_CTerminalpeptidylPhenylalanineamidation',s("The","formation","of","a","C-terminal","peptidyl-phenylalanine","amide","by","hydrolysis","and","oxidation","of","an","interior","Phe-Gly","peptide","in","a","secreted","protein","."),4283285). assertion_content_comment('oboGo_CTerminalpeptidylPolyglutamicacidamidation',s("The","formation","of","a","C-terminal","peptidyl-polyglutamic","acid","to","form","a","peptidyl-N-L-glutamyl-poly-L-glutamic","acid","C-terminus","."),4284464). assertion_content_comment('oboGo_CTerminalpeptidylProlineamidation',s("The","formation","of","a","C-terminal","peptidyl-proline","amide","by","hydrolysis","and","oxidation","of","an","interior","Pro-Gly","peptide","in","a","secreted","protein","."),4283274). assertion_content_comment('oboGo_CTerminalpeptidylSerineamidation',s("The","formation","of","a","C-terminal","peptidyl-serine","amide","by","hydrolysis","and","oxidation","of","an","interior","Ser-Gly","peptide","in","a","secreted","protein","."),4283263). assertion_content_comment('oboGo_CTerminalpeptidylThreonineamidation',s("The","formation","of","a","C-terminal","peptidyl-threonine","amide","by","hydrolysis","and","oxidation","of","an","interior","Thr-Gly","peptide","in","a","secreted","protein","."),4283176). assertion_content_comment('oboGo_CTerminalpeptidylTryptophanamidation',s("The","formation","of","a","C-terminal","peptidyl-tryptophan","amide","by","hydrolysis","and","oxidation","of","an","interior","Trp-Gly","peptide","in","a","secreted","protein","."),4283187). assertion_content_comment('oboGo_CTerminalpeptidylTyrosineamidation',s("The","formation","of","a","C-terminal","peptidyl-tyrosine","amide","by","hydrolysis","and","oxidation","of","an","interior","Tyr-Gly","peptide","in","a","secreted","protein","."),4283198). assertion_content_comment('oboGo_CTerminalpeptidylValineamidation',s("The","formation","of","a","C-terminal","peptidyl-valine","amide","by","hydrolysis","and","oxidation","of","an","interior","Val-Gly","peptide","in","a","secreted","protein","."),4283133). assertion_content_comment('oboGo_CTerminalprocessingpeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","cleavage","of","peptides","after","specific","recognition","of","a","C-terminal","tripeptide",",","Xaa-Yaa-Zaa",",","in","which","Xaa","is","preferably","Ala","or","Leu",",","Yaa","is","preferably","Ala","or","Tyr",",","and","Zaa","is","preferably","Ala",".","Cleavage","is","at","a","variable","distance","from","the","C-terminus",";","a","typical","cleavage","is","-Ala-Ala-Arg-Ala-Ala-Lys-Glu-Asn-Tyr-Ala-Leu-Ala-Ala","."),4237325). assertion_content_comment('oboGo_CTerminalproteinaminoacidmodification',s("The","alteration","of","the","C-terminal","amino","acid","residue","in","a","protein","."),4231152). assertion_content_comment('oboGo_CTerminalproteindeglutamylation',s("The","removal","of","a","C-terminal",",","gene-encoded","glutamate","residue","from","a","protein","."),4379899). assertion_content_comment('oboGo_CTerminalproteinfarnesylation',s("OBSOLETE",".","The","covalent","or","non-covalent","attachment","of","a","farnesyl","group","to","the","carboxy","terminus","of","a","protein","."),4231293). assertion_content_comment('oboGo_CTerminalproteingeranylgeranylation',s("OBSOLETE",".","The","covalent","or","non-covalent","attachment","of","a","geranylgeranyl","group","to","the","carboxy","terminus","of","a","protein","."),4231237). assertion_content_comment('oboGo_CTerminalproteinlipidation',s("The","covalent","attachment","of","a","lipid","group","to","the","carboxy","terminus","of","a","protein","."),4231258). assertion_content_comment('oboGo_CTerminalproteinmethylation',s("The","methylation","of","the","C-terminal","amino","acid","of","a","protein","."),4231156). assertion_content_comment('oboGo_CTerminalproteinprenylation',s("OBSOLETE",".","The","covalent","or","non-covalent","attachment","of","a","prenyl","group","to","the","carboxy","terminus","of","a","protein",";","geranyl",",","farnesyl",",","or","geranylgeranyl","groups","may","be","added","."),4231269). assertion_content_comment('oboGo_CTerminalproteinTyrosinylation',s("The","ATP-dependent","addition","of","a","tyrosine","residue","to","the","C-terminus","of","a","protein",";","typically","the","addition","of","tyrosine","to","the","C-terminus","of","detyrosinated","alpha-tubulin","by","the","enzyme","tubulin-tyrosine","ligase","."),4282620). assertion_content_comment('oboGo_Ctf18RFCLikecomplex',s("A","heptameric","complex","related","to","replication","factor","C",",","which","loads","the","DNA","polymerase","processivity","factor","proliferating","cell","nuclear","antigen","(","PCNA",")","onto","DNA","and","plays","a","vital","role","in","chromosome","cohesion",".","In","Saccharomyces","the","subunits","are","known","as","Ctf18p",",","Rfc2p",",","Rfc3p",",","Rfc4p",",","Rfc5p",",","Dcc1p",",","and","Ctf8p","."),4319875). assertion_content_comment('oboGo_CTP_23_Di_O_Geranylgeranyl_Sn_Glycero_1_PhosphateCytidyltransferaseActivity',s("Catalysis","of","the","reaction",":","CTP","+","2",",","3-di-O-geranylgeranyl-sn-glycero-1-phosphate","=","CDP-2",",","3-di-O-geranylgeranyl-sn-glycerol","."),4318294). assertion_content_comment('oboGo_CTP_2_Trans_6_Trans_FarnesolKinaseActivity',s("Catalysis","of","the","reaction",":","2-trans",",","-6-trans-farnesol","+","CTP","=","2-trans",",","-6-trans-farnesyl","monophosphate","+","CDP","+","H","+"),4192156). assertion_content_comment('oboGo_CUACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CUA","codon","."),4340263). assertion_content_comment('oboGo_CUCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CUC","codon","."),4340251). assertion_content_comment('oboGo_CucurbitacinDelta23Reductaseactivity',s("Catalysis","of","the","reaction",":","23",",","24-dihydrocucurbitacin","+","NAD","(","P",")","+","=","cucurbitacin","+","NAD","(","P",")","H","+","H","+"),4373744). assertion_content_comment('oboGo_CUGBP1Eif2complex',s("A","protein","complex","that","contains","the","eukaryotic","translation","initiation","factor","2","complex","(","EIF2",")",",","CUG","binding","protein","1",",","and","several","endoplasmic","reticulum","proteins",";","the","complex","is","involved","in","the","regulation","of","translation","."),4166913). assertion_content_comment('oboGo_CUGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CUG","codon","."),4340239). assertion_content_comment('oboGo_Cul2Ringubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul2","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","an","elongin-BC","adaptor","and","a","SOCS/BC","box","protein","."),4321432). assertion_content_comment('oboGo_Cul3Ringubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul3","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","a","BTB-domain-containing","protein","."),4321382). assertion_content_comment('oboGo_Cul4ARingubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul4A","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","an","adaptor","protein","."),4321367). assertion_content_comment('oboGo_Cul4BRingubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul4B","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","unknown","subunits","."),4321411). assertion_content_comment('oboGo_Cul5Ringubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul5","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","an","elongin-BC","adaptor","and","a","SOCS/BC","box","protein","."),4321397). assertion_content_comment('oboGo_Cul7Ringubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul7","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",";","substrate","specificity","is","conferred","by","a","Skp1","linker","and","an","F-box","protein","."),4321683). assertion_content_comment('oboGo_Cul8Ringubiquitinligasecomplex',s("A","ubiquitin","ligase","complex","in","which","a","cullin","from","the","Cul8","subfamily","and","a","RING","domain","protein","form","the","catalytic","core",".","In","S",".","cerevisiae",",","Mms1p","acts","as","the","adaptor","protein","and","substrate","specificity","is","conferred","by","any","of","a","number","of","different","proteins","."),4383028). assertion_content_comment('oboGo_CullinRingubiquitinligasecomplex',s("Any","ubiquitin","ligase","complex","in","which","the","catalytic","core","consists","of","a","member","of","the","cullin","family","and","a","RING","domain","protein",";","the","core","is","associated","with","one","or","more","additional","proteins","that","confer","substrate","specificity","."),4182942). assertion_content_comment('oboGo_CuticleDevelopmentInvolvedInChitinBasedcuticlemoltingcycle',s("The","synthesis","and","deposition","of","a","chitin-based","non-cellular",",","hardened",",","or","membranous","secretion","from","an","epithelial","sheet",",","occurring","as","part","of","the","molting","cycle",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4020647). assertion_content_comment('oboGo_CuticleDevelopmentInvolvedInCollagenAndCuticulinBasedcuticlemoltingcycle',s("Synthesis","and","deposition","of","a","collagen","and","cuticulin-based","noncellular",",","hardened",",","or","membranous","secretion","from","an","epithelial","sheet",",","occurring","as","part","of","the","molting","cycle",".","An","example","of","this","process","is","found","in","Caenorhabditis","elegans","."),4079620). assertion_content_comment('oboGo_CuticleDevelopmentInvolvedInProteinBasedcuticlemoltingcycle',s("Synthesis","and","deposition","of","a","protein-based","noncellular",",","hardened",",","or","membranous","secretion","from","an","epithelial","sheet",",","occurring","as","part","of","the","molting","cycle",".","Examples","of","this","process","are","found","in","invertebrate","species","."),4020640). assertion_content_comment('oboGo_CUUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","CUU","codon","."),4340310). assertion_content_comment('oboGo_CX3Cchemokinebinding',s("Interacting","selectively","and","non-covalently","with","a","C-X3-C","chemokine",";","C-X3-C","chemokines","have","three","amino","acids","between","the","first","two","cysteines","of","the","characteristic","four-cysteine","motif","."),4233112). assertion_content_comment('oboGo_CX3Cchemokinereceptoractivity',s("Combining","with","a","C-X3-C","chemokine","to","initiate","a","change","in","cell","activity",".","A","C-X3-C","chemokine","has","three","amino","acids","between","the","first","two","cysteines","of","the","characteristic","four-cysteine","motif","."),4305015). assertion_content_comment('oboGo_CXCchemokinebinding',s("Interacting","selectively","and","non-covalently","with","a","C-X-C","chemokine",";","C-X-C","chemokines","have","a","single","amino","acid","between","the","first","two","cysteines","of","the","characteristic","four","cysteine","motif","."),4198678). assertion_content_comment('oboGo_CXCchemokinereceptoractivity',s("Combining","with","a","C-X-C","chemokine","to","initiate","a","change","in","cell","activity",".","A","C-X-C","chemokine","has","a","single","amino","acid","between","the","first","two","cysteines","of","the","characteristic","four","cysteine","motif","."),4198680). assertion_content_comment('oboGo_Cyanidin3OGlucosidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","cyanidin","3-O-glucoside",",","a","basic","anthocyanin","responsible","for","red","to","magenta","coloration","of","flowers","and","fruits","."),4339277). assertion_content_comment('oboGo_Cyanidin_3_Rhamnosylglucoside5_O_GlucosyltransferaseActivity',s("Catalysis","of","the","reaction",":","cyanidin-3-O-D-rhamnosyl-","(","1",",","6",")","-D-glucoside","+","UDP-D-glucose","=","cyanidin-3-O-","[","D-rhamnosyl-","(","1",",","6",")","-D-glucoside","]","-5-O-D-glucoside","+","UDP","."),4366629). assertion_content_comment('oboGo_CyanocobalaminReductaseCyanideEliminatingactivity',s("Catalysis","of","the","reaction",":","cob","(","I",")","alamin","+","hydrogen","cyanide","+","NADP","(","+",")","=","cyanocob","(","III",")","alamin","+","H","(","+",")","+","NADPH","."),4342081). assertion_content_comment('oboGo_CyanohydrinBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","(","S",")","-4-hydroxymandelonitrile","=","UDP","+","(","S",")","-4-hydroxy-mandelonitrile","beta-D-glucoside","."),4373783). assertion_content_comment('oboGo_CyanophycinSynthetaseActivityLArginineAdding',s("Catalysis","of","the","reaction",":","ATP","+","[","L-Asp","(","4-L-Arg",")","]","n-L-Asp","+","L-arginine","=","ADP","+","phosphate","+","[","L-Asp","(","4-L-Arg",")","]","n","+","1","."),4164795). assertion_content_comment('oboGo_CyanophycinSynthetaseActivityLAspartateAdding',s("Catalysis","of","the","reaction",":","ATP","+","[","L-Asp","(","4-L-Arg",")","]","n","+","L-Asp","=","ADP","+","phosphate","+","[","L-Asp","(","4-L-Arg",")","]","n-L-Asp","."),4164805). assertion_content_comment('oboGo_CyclicDiGmpbinding',s("Interacting","selectively","and","non-covalently","with","cyclic-di-GMP",",","cyclic","dimeric","guanosine","monophosphate","."),4375609). assertion_content_comment('oboGo_CyclicGuanylateSpecificphosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","cyclic","di-3","'",",","5","'","-guanylate","+","H","(","2",")","O","=","5","'","-phosphoguanylyl","(","3","'","-","&","gt",";","5","'",")","guanosine","+","H","(","+",")"),4164402). assertion_content_comment('oboGo_CyclicNucleotideDependentguanylNucleotideexchangefactoractivity',s("Stimulates","the","exchange","of","guanyl","nucleotides","associated","with","a","GTPase",";","dependent","on","the","presence","of","a","cyclic","nucleotide","."),4257962). assertion_content_comment('oboGo_CyclicNucleotideDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","presence","of","a","cyclic","nucleotide","."),4202536). assertion_content_comment('oboGo_CyclicNucleotideGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","a","cyclic","nucleotide","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4217672). assertion_content_comment('oboGo_CyclicNucleotideGatedmechanosensitiveionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","in","response","to","a","mechanical","stress","and","when","a","cyclic","nucleotide","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4327057). assertion_content_comment('oboGo_CyclicNucleotideMediatedsignaling',s("A","series","of","molecular","signals","in","which","a","cell","uses","a","cyclic","nucleotide","to","convert","an","extracellular","signal","into","a","response","."),4024718). assertion_content_comment('oboGo_CyclicNucleotidephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","a","nucleoside","cyclic","phosphate","+","H2O","=","a","nucleoside","phosphate","."),4211486). assertion_content_comment('oboGo_CyclicNucleotidephosphodiesterasecomplex',s("An","enzyme","complex","that","catalyzes","the","hydrolysis","of","bonds","in","a","cyclic","nucleotide","."),4221094). assertion_content_comment('oboGo_CyclinDependentproteinkinase5activatoractivity',s("Increases","the","activity","of","cyclin-dependent","protein","kinase","5","."),4305139). assertion_content_comment('oboGo_CyclinDependentproteinkinase5activatorregulatoractivity',s("Modulation","of","the","activity","of","cyclin-dependent","protein","kinase","5","activator","."),4305149). assertion_content_comment('oboGo_CyclinDependentproteinkinase5holoenzymecomplex',s("A","protein","complex","that","activates","cyclin-dependent","kinase","5",";","composed","of","regulatory","and","catalytic","subunits","."),4305119). assertion_content_comment('oboGo_CyclinDependentproteinkinaseactivatingkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",";","increases","the","activity","of","a","cyclin-dependent","protein","kinase","(","CDK",")"),4232880). assertion_content_comment('oboGo_CyclinDependentproteinkinaseactivatingkinaseholoenzymecomplex',s("A","protein","complex","that","phosphorylates","cyclin-dependent","kinases","such","as","Cdc2","on","Thr161","(","or","an","equivalent","residue",")",";","contains","a","catalytic","subunit","and","a","regulatory","subunit",",","and","some","examples","also","include","an","assembly","factor","."),4232814). assertion_content_comment('oboGo_CyclinDependentproteinkinaseactivatingkinaseregulatoractivity',s("Modulation","of","the","activity","of","the","enzyme","cyclin-dependent","protein","kinase","activating","kinase","."),4232858). assertion_content_comment('oboGo_CyclinDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","binding","of","a","regulatory","cyclin","subunit","and","full","activity","requires","stimulatory","phosphorylation","by","a","CDK-activating","kinase","(","CAK",")"),4202557). assertion_content_comment('oboGo_CyclinDependentproteinkinaseholoenzymecomplex',s("Cyclin-dependent","protein","kinases","(","CDKs",")","are","heterodimeric","enzymes","that","contain","a","kinase","catalytic","subunit","associated","with","a","regulatory","cyclin","partner","."),4232834). assertion_content_comment('oboGo_CyclinDependentproteinkinaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","a","cyclin-dependent","protein","kinase","."),4200318). assertion_content_comment('oboGo_CyclinDependentproteinkinaseregulatoractivity',s("Modulates","the","activity","of","a","cyclin-dependent","protein","kinase",",","enzymes","of","the","protein","kinase","family","that","are","regulated","through","association","with","cyclins","and","other","proteins","."),4200280). assertion_content_comment('oboGo_CyclizationOfAsparagineInvolvedInInteinMediatedproteinsplicing',s("The","cyclization","of","asparagine","to","yield","an","L-aspartimide","(","otherwise","known","as","alpha-aminosuccinimide",")","residue","at","the","C-terminus","of","an","excised","intein","during","protein","splicing","."),4042365). assertion_content_comment('oboGo_CyclizationOfGlutamineInvolvedInInteinMediatedproteinsplicing',s("The","cyclization","of","glutamine","to","yield","an","L-glutamimide","residue","at","the","C-terminus","of","an","excised","intein","during","protein","splicing","."),4042389). assertion_content_comment('oboGo_Cycloartenol24CMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","cycloartenol","=","(","24R",")","-24-methylcycloart-25-en-3beta-ol","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308963). assertion_content_comment('oboGo_Cyclohex_1_Ene_1_Carboxyl_CoAHydrataseActivity',s("Catalysis","of","the","reaction",":","cyclohex-1-ene-1-carboxyl-CoA","+","H2O","=","2-hydroxycyclohexane-1-carboxyl-CoA","."),4273931). assertion_content_comment('oboGo_Cyclohexa_15_Dienecarbonyl_CoAHydrataseActivity',s("Catalysis","of","the","reaction",":","cyclohexa-1",",","5-diene-1-carbonyl-CoA","+","H","(","2",")","O","=","6-hydroxycyclohex-1-enecarbonyl-CoA","."),4273682). assertion_content_comment('oboGo_Cyclohexane_12_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","trans-cyclohexane-1",",","2-diol","+","NAD","+","=","2-hydroxycyclohexan-1-one","+","NADH","."),4373670). assertion_content_comment('oboGo_Cyclohexane_13_DioneHydrolaseActivity',s("Catalysis","of","the","reaction",":","cyclohexane-1",",","3-dione","+","H","(","2",")","O","=","5-oxohexanoate","+","H","(","+",")"),4373707). assertion_content_comment('oboGo_CyclohexylIsocyanidehydrataseactivity',s("Catalysis","of","the","reaction",":","N-cyclohexylformamide","+","H","(","+",")","=","cyclohexyl","isocyanide","+","H","(","2",")","O","."),4268914). assertion_content_comment('oboGo_CycloLigaseactivity',s("Catalysis","of","the","joining","of","two","groups","within","a","single","molecule","via","a","carbon-nitrogen","bond",",","forming","heterocyclic","ring",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4203493). assertion_content_comment('oboGo_CyclophilinTypepeptidylProlylcisTransisomeraseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","peptidylproline","(","omega","=","180",")","=","peptidylproline","(","omega","=","0",")"),4306294). assertion_content_comment('oboGo_CyclopropanecarboxylateCoaligaseactivity',s("Catalysis","of","the","reaction",":","cyclopropanecarboxylate","+","CoASH","=","cyclopropanecarboxyl-CoA","+","OH-","."),4349927). assertion_content_comment('oboGo_CyclopropanecarboxylCoadecyclaseactivity',s("Catalysis","of","the","reaction",":","cyclopropanecarboxyl-CoA","=","crotonoyl-CoA","."),4349902). assertion_content_comment('oboGo_CyclopropaneFattyAcylPhospholipidsynthaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","phospholipid","olefinic","fatty","acid","=","S-adenosyl-L-homocysteine","+","phospholipid","cyclopropane","fatty","acid","."),4250161). assertion_content_comment('oboGo_CypridinaLuciferin2Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","Cypridina","luciferin","+","O2","=","oxidized","Cypridina","luciferin","+","CO2","+","light","."),4374472). assertion_content_comment('oboGo_CystathionineBetaLyaseactivity',s("Catalysis","of","the","reaction",":","cystathionine","+","H2O","=","L-homocysteine","+","NH3","+","pyruvate","."),4211518). assertion_content_comment('oboGo_CystathionineBetaSynthaseactivity',s("Catalysis","of","the","reaction",":","L-serine","+","L-homocysteine","=","cystathionine","+","H2O","."),4211432). assertion_content_comment('oboGo_CystathionineGammaLyaseactivity',s("Catalysis","of","the","reaction",":","L-cystathionine","+","H2O","=","L-cysteine","+","NH3","+","2-oxobutanoate","."),4211449). assertion_content_comment('oboGo_CystathionineGammaSynthaseactivity',s("Catalysis","of","the","reaction",":","O-succinyl-L-homoserine","+","L-cysteine","=","cystathionine","+","succinate","."),4185142). assertion_content_comment('oboGo_CysteineBiosyntheticProcessViaSSulfoLCysteine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","cysteine",",","via","the","intermediate","S-sulfo-L-cysteine","."),4240338). assertion_content_comment('oboGo_CysteineConjugatetransaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","S-","(","4-bromophenyl",")","-L-cysteine","=","(","4-bromophenylsulfanyl",")","pyruvate","+","L-glutamate","."),4375107). assertion_content_comment('oboGo_CysteineExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","cysteine","(","in",")","=","ADP","+","phosphate","+","cysteine","(","out",")"),4331525). assertion_content_comment('oboGo_CysteineGlucosaminylinositolligaseactivity',s("Catalysis","of","the","reaction",":","1-","(","2-amino-2-deoxy-alpha-D-glucopyranoside",")","-1D-myo-inositol","+","L-cysteine","+","ATP","=","1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside","+","AMP","+","diphosphate","+","2","H","+","1-","(","2-amino-2-deoxy-alpha-D-glucopyranoside",")","-1D-myo-inositol","is","also","known","as","glucosaminyl-inositol","or","GlcN-Ins",",","and","1-D-myo-inosityl-2-L-cysteinylamido-2-deoxy-alpha-D-glucopyranoside","as","desacetylmycothiol","or","Cys-GlcN-Ins","."),4375645). assertion_content_comment('oboGo_CysteineSConjugatebetaLyaseactivity',s("Catalysis","of","the","reaction",":","RS-CH2-CH","(","NH3","+",")","COO-","=","RSH","+","NH3","+","pyruvate","."),4375136). assertion_content_comment('oboGo_CysteineSConjugatenAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-substituted","L-cysteine","+","acetyl-CoA","=","S-substituted","N-acetyl-L-cysteine","+","CoA","+","H","(","+",")"),4366143). assertion_content_comment('oboGo_CysteineTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","cysteine","(","out/in",")","=","ADP","+","phosphate","+","cysteine","(","in/out",")"),4331523). assertion_content_comment('oboGo_CysteineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-cysteine","+","tRNA","(","Cys",")","=","AMP","+","diphosphate","+","L-cysteinyl-tRNA","(","Cys",")"),4200017). assertion_content_comment('oboGo_CysteineTypeaminopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","N-terminal","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4180823). assertion_content_comment('oboGo_CysteineTypecarboxypeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","C-terminal","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4301634). assertion_content_comment('oboGo_CysteineTypeendopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","internal",",","alpha-peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4179629). assertion_content_comment('oboGo_CysteineTypeendopeptidaseinhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","a","cysteine-type","endopeptidase",",","any","enzyme","that","hydrolyzes","peptide","bonds","in","polypeptides","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4200389). assertion_content_comment('oboGo_CysteineTypeexopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","C-","or","N-terminal","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4180821). assertion_content_comment('oboGo_CysteineTypepeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","in","which","the","sulfhydryl","group","of","a","cysteine","residue","at","the","active","center","acts","as","a","nucleophile","."),4171253). assertion_content_comment('oboGo_CysteinylTrnaaminoacylation',s("The","process","of","coupling","cysteine","to","cysteinyl-tRNA",",","catalyzed","by","cysteinyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179759). assertion_content_comment('oboGo_CysTrnaprohydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","misacylated","Cys-tRNA","(","Pro",")"),4328719). assertion_content_comment('oboGo_CytochromeB5reductaseactivity',s("Catalysis","of","the","reaction",":","NADH","+","H","+","+","2","ferricytochrome","b","(","5",")","=","NAD","+","+","2","ferrocytochrome","b","(","5",")"),4211533). assertion_content_comment('oboGo_CytochromeC3hydrogenaseactivity',s("Catalysis","of","the","reaction",":","2","H2","+","ferricytochrome","c3","=","4","H","+","+","ferrocytochrome","c3","."),4375058). assertion_content_comment('oboGo_CytochromeCArgininenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","cytochrome","c",")","-arginine","=","S-adenosyl-L-homocysteine","+","(","cytochrome","c",")","-N","(","omega",")","-methyl-arginine","."),4303681). assertion_content_comment('oboGo_CytochromeCHemelinkage',s("The","linkage","of","cytochromes","and","other","heme","proteins","to","heme","."),4281946). assertion_content_comment('oboGo_CytochromeCHemelinkageviahemeBisLCysteine',s("The","linkage","of","cytochromes","and","other","heme","proteins","to","heme","via","heme-bis-L-cysteine","."),4281962). assertion_content_comment('oboGo_CytochromeCHemelinkageviahemeLCysteine',s("The","linkage","of","cytochromes","and","other","heme","proteins","to","heme","via","heme-L-cysteine","."),4281950). assertion_content_comment('oboGo_CytochromeCLysinenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","cytochrome","c","L-lysine","=","S-adenosyl-L-homocysteine","+","cytochrome","c","N6-methyl-L-lysine",".","This","is","the","addition","of","a","methyl","group","to","the","N6","atom","of","a","lysine","residue","in","cytochrome","c","."),4346644). assertion_content_comment('oboGo_CytochromeCMethioninesMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","[","cytochrome","c","]","-methionine","=","S-adenosyl-L-homocysteine","+","[","cytochrome","c","]","-S-methyl-methionine","."),4309231). assertion_content_comment('oboGo_CytochromeCoxidaseactivity',s("Catalysis","of","the","reaction",":","4","ferrocytochrome","c","+","O2","+","4","H","+","=","4","ferricytochrome","c","+","2","H2O","."),4211589). assertion_content_comment('oboGo_CytochromeCperoxidaseactivity',s("Catalysis","of","the","reaction",":","2","ferrocytochrome","c","+","hydrogen","peroxide","=","2","ferricytochrome","c","+","2","H2O","."),4211765). assertion_content_comment('oboGo_CytochromeP4504A1Hemelinkage',s("The","covalent","linkage","of","heme","to","cytochrome","P450","4A1","via","hydroxyheme-L-glutamyl","ester","."),4298648). assertion_content_comment('oboGo_CytokineMediatedsignalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","a","cytokine","or","chemokine","binding","to","a","cell","surface","receptor","."),3987710). assertion_content_comment('oboGo_Cytokinin7BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","N6-alkylaminopurine","=","UDP","+","N6-alkylaminopurine-7-beta-D-glucoside","."),4375042). assertion_content_comment('oboGo_Cytokinin9BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","N6-alkylaminopurine","=","UDP","+","N6-alkylaminopurine-9-beta-D-glucoside","."),4182603). assertion_content_comment('oboGo_CytoplasmAssociatedproteasomalubiquitinDependentproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","misfolded","proteins","in","the","cytoplasm",",","which","are","targeted","to","cytoplasmic","proteasomes","for","degradation","."),4172867). assertion_content_comment('oboGo_CytoplasmicActinBasedcontractioninvolvedincellmotility',s("The","actin","filament-based","movement","by","which","cytoplasmic","actin","filaments","slide","past","one","another","resulting","in","a","contraction","that","propels","the","cell","from","one","place","to","another","."),4114783). assertion_content_comment('oboGo_CytoplasmicActinBasedcontractioninvolvedinforwardcellmotility',s("The","actin","filament-based","movement","by","which","cytoplasmic","actin","filaments","slide","past","one","another","resulting","in","a","contraction","that","propels","the","cell","in","the","direction","that","has","been","defined","as","the","front","of","the","cell","."),4160501). assertion_content_comment('oboGo_CytoplasmicActinBasedcontractioninvolvedinrearwardcellmotility',s("The","actin","filament-based","movement","by","which","cytoplasmic","actin","filaments","slide","past","one","another","resulting","in","a","contraction","that","propels","the","cell","in","the","direction","that","has","been","defined","as","the","rear","of","the","cell","."),4160491). assertion_content_comment('oboGo_CytoplasmicCyclinDependentproteinkinaseholoenzymecomplex',s("Cyclin-dependent","protein","kinase","(","CDK",")","complex","found","in","the","cytoplasm","."),4362990). assertion_content_comment('oboGo_CytoplasmicMembraneBoundedvesiclelumen',s("The","volume","enclosed","by","the","membrane","of","a","cytoplasmic","membrane-bounded","vesicle","."),4057738). assertion_content_comment('oboGo_CytoplasmicMembraneBoundedvesicle',s("A","membrane-bounded","vesicle","found","in","the","cytoplasm","of","the","cell","."),3979448). assertion_content_comment('oboGo_CytoplasmicPolyadenylationDependentrrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","cytoplasm","and","resulting","in","the","breakdown","of","a","ribosomal","RNA","(","rRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","rRNA","truncated","degradation","intermediate","."),4381186). assertion_content_comment('oboGo_CytoplasmicSequesteringOfNFKappab',s("The","selective","interaction","of","the","transcription","factor","NF-kappaB","with","specific","molecules","in","the","cytoplasm",",","thereby","inhibiting","its","translocation","into","the","nucleus","."),4016491). assertion_content_comment('oboGo_CytosineC_5DNADemethylaseActivity',s("Catalysis","of","the","reaction",":","methyl-dCpdG","DNA","+","H2O","=","dCpdG","DNA","+","methanol",".","This","reaction","is","the","hydrolytic","removal","of","the","methyl","group","on","the","5","position","of","cytosine","in","DNA","."),4279821). assertion_content_comment('oboGo_CytoskeletonDependentcytoplasmictransportnursecelltooocyte',s("The","directed","movement","of","substances","along","cytoskeletal","elements",",","such","as","microfilaments","or","microtubules",",","from","a","nurse","cell","to","an","oocyte","."),4244919). assertion_content_comment('oboGo_CytoskeletonDependentintracellulartransport',s("The","directed","movement","of","substances","along","cytoskeletal","elements","such","as","microfilaments","or","microtubules","within","a","cell","."),3977912). assertion_content_comment('oboGo_CytoskeletonMediatedcellswimming',s("Cell","motility","in","which","contractile","cytoskeletal","elements","alter","cell","shape",",","resulting","in","the","smooth","movement","of","a","cell","through","a","liquid","medium","."),4168443). assertion_content_comment('oboGo_CytosolicAlphaKetoglutaratedehydrogenasecomplex',s("Cytosolic","complex","that","possesses","alpha-ketoglutarate","dehydrogenase","activity","."),4298774). assertion_content_comment('oboGo_CytosolicCalciumSignalingInvolvedInInitiationOfCellMovementInGlialMediatedradialcellmigration',s("The","process","that","results","in","the","fluctuations","in","intracellular","calcium","that","are","responsible","for","the","initiation","of","movement","as","a","component","of","the","process","of","cerebral","cortex","glial-mediated","radial","migration","."),4050192). assertion_content_comment('oboGo_CytosolicDNADirectedrnapolymerasecomplex',s("The","eubacterial","DNA-directed","RNA","polymerase","is","a","multisubunit","complex","with","a","core","composed","of","the","essential","subunits","beta-prime",",","beta",",","and","two","copies","of","alpha","and","a","fifth","nonessential","subunit","called","omega",".","An","additional","subunit",",","a","sigma","factor",",","is","required","for","promoter","recognition","and","specificity","."),4362863). assertion_content_comment('oboGo_CytosolicLargeRibosomalSubunit_3',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4345915). assertion_content_comment('oboGo_CytosolicProteasomeCoreComplexAlphaSubunitcomplex',s("The","proteasome","core","subcomplex","that","constitutes","the","two","outer","rings","of","the","cytosolic","proteasome","core","complex","."),4060328). assertion_content_comment('oboGo_CytosolicProteasomeCoreComplexBetaSubunitcomplex',s("The","proteasome","core","subcomplex","that","constitutes","the","two","inner","rings","of","the","cytosolic","proteasome","core","complex","."),4060306). assertion_content_comment('oboGo_CytosolicSmallRibosomalSubunit_7',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4345926). assertion_content_comment('oboGo_D_2_Hydroxy_AcidDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","(","R",")","-lactate","+","A","=","AH","(","2",")","+","pyruvate","."),4375072). assertion_content_comment('oboGo_D_4_HydroxyphenylglycineTransaminaseActivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","D-4-hydroxyphenylglycine","=","4-hydroxyphenylglyoxylate","+","L-glutamate","."),4369089). assertion_content_comment('oboGo_DAlanine2Hydroxymethyltransferaseactivity',s("Catalysis","of","the","reaction",":","5",",","10-methylenetetrahydrofolate","+","D-alanine","+","H","(","2",")","O","=","(","6S",")","-5",",","6",",","7",",","8-tetrahydrofolate","+","2-methylserine","."),4266610). assertion_content_comment('oboGo_DAlanine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","D-alanine","+","2-oxoglutarate","=","pyruvate","+","D-glutamate","."),4375001). assertion_content_comment('oboGo_DAlanineAlanylPolyglycerolphosphateligaseactivity',s("Catalysis","of","the","reaction",":","alanyl-poly","(","glycerolphosphate",")","+","D-alanine","+","ATP","=","D-alanyl-alanyl-poly","(","glycerolphosphate",")","+","phosphate","+","ADP","."),4369824). assertion_content_comment('oboGo_DAlaninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-alanine",",","the","D-enantiomer","of","the","amino","acid","alanine",",","i.e","(","2R",")","-2-aminopropanoic","acid","."),4308118). assertion_content_comment('oboGo_DAlaninecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-alanine",",","the","D-enantiomer","of","the","amino","acid","alanine","."),4222284). assertion_content_comment('oboGo_DAlanineDAlanineligaseactivity',s("Catalysis","of","the","reaction",":","2","D-alanine","+","ATP","=","D-alanyl-D-alanine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4252068). assertion_content_comment('oboGo_DAlaninefamilyaminoacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-alanine","and","related","amino","acids","."),4308110). assertion_content_comment('oboGo_DAlaninefamilyaminoacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-alanine","and","related","amino","acids","."),4308157). assertion_content_comment('oboGo_DAlaninefamilyaminoacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-alanine","and","related","amino","acids","."),4222277). assertion_content_comment('oboGo_DAlaninegammaGlutamyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-alanine","+","L-glutamine","=","gamma-L-glutamyl-D-alanine","+","NH","(","4",")","(","+",")"),4375019). assertion_content_comment('oboGo_DAlaninemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-alanine",",","the","D-enantiomer","of","the","amino","acid","alanine",",","i.e",".","(","2R",")","-2-aminopropanoic","acid","."),4222281). assertion_content_comment('oboGo_DAlaninePolyphosphoribitolligaseactivity',s("Catalysis","of","the","reaction",":","poly","(","ribitol","phosphate",")","+","D-alanine","+","ATP","=","O-D-alanyl-poly","(","ribitol","phosphate",")","+","diphosphate","+","AMP","."),4369656). assertion_content_comment('oboGo_DAlaninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-alanine","from","one","side","of","a","membrane","to","the","other",".","D-alanine","is","the","D-enantiomer","of","2-aminopropanoic","acid","."),4315642). assertion_content_comment('oboGo_DAlaninetransport',s("The","directed","movement","of","D-alanine",",","the","D-enantiomer","of","2-aminopropanoic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4315631). assertion_content_comment('oboGo_DAlanylDAlanineendopeptidaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4252112). assertion_content_comment('oboGo_DAllosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-allose",",","the","D-enantiomer","of","allo-hexose",",","an","aldohexose","similar","to","glucose","."),4240160). assertion_content_comment('oboGo_DAllosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-allose",",","the","D-enantiomer","of","allo-hexose",",","an","aldohexose","similar","to","glucose","."),4240131). assertion_content_comment('oboGo_DAlloseImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-allose","(","out",")","=","ADP","+","phosphate","+","D-allose","(","in",")"),4289607). assertion_content_comment('oboGo_DAllosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-allose",",","the","D-enantiomer","of","allo-hexose",",","an","aldohexose","similar","to","glucose","."),4240113). assertion_content_comment('oboGo_DAminoacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-amino","acids",",","the","D-enantiomers","of","amino","acids","."),4179162). assertion_content_comment('oboGo_DAminoacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-amino","acids",",","the","D-enantiomers","of","amino","acids","."),4222233). assertion_content_comment('oboGo_DAminoAciddehydrogenaseactivity',s("Catalysis","of","the","reaction",":","a","D-amino","acid","+","H2O","+","acceptor","=","a","2-oxo","acid","+","NH3","+","reduced","acceptor","."),4252098). assertion_content_comment('oboGo_DAminoAciddehydrogenasecomplex',s("A","protein","complex","that","possesses","D-amino-acid","dehydrogenase","activity","."),4259827). assertion_content_comment('oboGo_DAminoacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-amino","acids",",","the","D-enantiomers","of","amino","acids","."),4179159). assertion_content_comment('oboGo_DAminoAcidnAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","a","D-amino","acid","=","CoA","+","an","N-acetyl-D-amino-acid","."),4375030). assertion_content_comment('oboGo_DAminoAcidoxidaseactivity',s("Catalysis","of","the","reaction",":","a","D-amino","acid","+","H2O","+","O2","=","a","2-oxo","acid","+","NH3","+","hydrogen","peroxide","."),4189992). assertion_content_comment('oboGo_DAminoacidtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-amino","acids","from","one","side","of","a","membrane","to","the","other",".","D-amino","acids","are","the","D-enantiomers","of","amino","acids","."),4315619). assertion_content_comment('oboGo_DAminoacidtransport',s("The","directed","movement","of","the","D-enantiomer","of","an","amino","acid","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4176446). assertion_content_comment('oboGo_DAminoacylTrnadeacylaseactivity',s("Catalysis","of","the","reaction",":","D-aminoacyl-tRNA","=","D-amino","acid","+","tRNA",".","Hydrolysis","of","the","removal","of","D-amino","acids","from","residues","in","charged","tRNA","."),4283364). assertion_content_comment('oboGo_DArabinitol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-arabinitol","+","NAD","(","+",")","=","D-ribulose","+","H","(","+",")","+","NADH","."),4364381). assertion_content_comment('oboGo_DArabinitol4Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-arabinitol","+","NAD","+","=","D-xylulose","+","NADH","."),4375265). assertion_content_comment('oboGo_DArabinitoldehydrogenasedRibuloseformingnadpactivity',s("Catalysis","of","the","reactions",":","D-arabinitol","+","NADP","+","=","D-ribulose","+","NADPH","+","H","+"),4341866). assertion_content_comment('oboGo_DArabinitoldehydrogenasedXyluloseformingnadpactivity',s("Catalysis","of","the","reaction",":","D-arabinitol","+","NADP","+","=","D-xylulose","+","NADPH","+","H","+"),4191317). assertion_content_comment('oboGo_DArabinokinaseactivity',s("Catalysis","of","the","reaction",":","D-arabinose","+","ATP","=","D-arabinose","5-phosphate","+","ADP","."),4375253). assertion_content_comment('oboGo_D_Arabinono_14_LactoneOxidaseActivity',s("Catalysis","of","the","reaction",":","D-arabinono-1",",","4-lactone","+","O","(","2",")","=","dehydro-D-arabinono-1",",","4-lactone","+","H","(","2",")","O","(","2",")","+","H","(","+",")"),4190005). assertion_content_comment('oboGo_DArabinonolactonaseactivity',s("Catalysis","of","the","reaction",":","D-arabinono-1",",","4-lactone","+","H","(","2",")","O","=","D-arabinonate","+","H","(","+",")"),4375242). assertion_content_comment('oboGo_DArabinose1Dehydrogenasenadactivity',s("Catalysis","of","the","reaction",":","D-arabinose","+","NAD","+","=","D-arabinono-1",",","4-lactone","+","NADH","."),4375230). assertion_content_comment('oboGo_DArabinose1Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","D-arabinose","+","NAD","(","P",")","+","=","D-arabinono-1",",","4-lactone","+","NAD","(","P",")","H","+","H","+"),4298726). assertion_content_comment('oboGo_DArabinosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-arabinose",",","the","D-enantiomer","of","arabino-pentose","."),4243230). assertion_content_comment('oboGo_DArabinosecatabolicprocesstoxylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-arabinose","to","form","xylulose","5-phosphate",".","D-arabinose","is","converted","into","D-ribulose",",","which","is","phosphorylated","to","ribulose-5-phosphate",",","which","is","isomerized","to","give","D-xylulose-5-phosphate","."),4243236). assertion_content_comment('oboGo_DArabinosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-arabinose",",","the","D-enantiomer","of","arabino-pentose",".","D-arabinose","occurs","in","plant","glycosides","and","is","a","constituent","of","arabinonucleosides","."),4243227). assertion_content_comment('oboGo_DArabitolcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-arabitol",",","the","pentitol","derived","from","arabinose","or","lyxose","by","reduction","of","the","aldehyde","group",".","The","D","enantiomer","is","present","in","lichens","and","mushrooms","."),4242467). assertion_content_comment('oboGo_DArabitolcatabolicprocesstoxylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-arabitol","to","form","xylulose","5-phosphate",".","D-arabitol","is","converted","into","D-xylulose",",","which","is","then","phosphorylated","to","form","D-xylulose-5-phosphate","."),4242473). assertion_content_comment('oboGo_DArabitolmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-arabitol",",","the","pentitol","derived","from","arabinose","or","lyxose","by","reduction","of","the","aldehyde","group",".","The","D","enantiomer","is","present","in","lichens","and","mushrooms","."),4242464). assertion_content_comment('oboGo_DArginaseactivity',s("Catalysis","of","the","reaction",":","D-arginine","+","H","(","2",")","O","=","D-ornithine","+","urea","."),4375220). assertion_content_comment('oboGo_DArgininemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-arginine",",","the","D-enantiomer","of","the","amino","acid","arginine",",","i.e",".","(","2R",")","-2-amino-5-","(","carbamimidamido",")","pentanoic","acid","."),4347211). assertion_content_comment('oboGo_DAspartateimport',s("The","directed","movement","of","D-aspartate",",","the","L-enantiomer","of","the","anion","of","2-aminopentanedioic","acid",",","into","a","cell","or","organelle","."),4176479). assertion_content_comment('oboGo_DAspartateligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","D-aspartate","+","[","beta-GlcNAc-","(","1-","&","gt",";","4",")","-Mur2Ac","(","oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala",")","]","n","=","[","beta-GlcNAc-","(","1-","&","gt",";","4",")","-Mur2Ac","(","oyl-L-Ala-gamma-D-Glu-6-N-","(","beta-D-Asp",")","-L-Lys-D-Ala-D-Ala",")","]","n","+","ADP","+","phosphate","."),4361043). assertion_content_comment('oboGo_DAspartateoxidaseactivity',s("Catalysis","of","the","reaction",":","D-aspartate","+","H2O","+","O2","=","oxaloacetate","+","NH3","+","hydrogen","peroxide","."),4253730). assertion_content_comment('oboGo_DAspartatetransport',s("The","directed","movement","of","D-aspartate",",","the","D-enantiomer","of","the","anion","of","(","2R",")","-2-aminobutanedioic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4176448). assertion_content_comment('oboGo_DATPDGTPDnapurinetransferaseactivity',s("Catalysis","of","the","reaction",":","dATP","+","depurinated","DNA","=","ribose","triphosphate","+","DNA","."),4374989). assertion_content_comment('oboGo_DaunorubicinTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","daunorubicin","(","in",")","=","ADP","+","phosphate","+","daunorubicin","(","out",")"),4318676). assertion_content_comment('oboGo_D_Benzoylarginine_4_NitroanilideAmidaseActivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-benzoyl-D-arginine-4-nitroanilide","+","H","(","2",")","O","=","4-nitroaniline","+","N","(","2",")","-benzoyl-D-arginine","+","H","(","+",")"),4370054). assertion_content_comment('oboGo_Dbf4Dependentproteinkinasecomplex',s("A","heterodimeric","protein","complex","required","for","the","activation","of","DNA","replication","origins",";","comprises","a","catalytic","subunit","and","a","regulatory","subunit","(","in","Saccharomyces",",","Cdc7p","and","Dbf4p",",","respectively",")",";","complexes","identified","in","other","species","generally","contain","proteins","related","to","the","Saccharomyces","proteins","."),4321305). assertion_content_comment('oboGo_DCTPDeaminaseDUMPFormingactivity',s("Catalysis","of","the","reaction",":","dCTP","+","2","H","(","2",")","O","=","diphosphate","+","dUMP","+","H","(","+",")","+","NH","(","4",")","(","+",")"),4345045). assertion_content_comment('oboGo_DCysteinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-cysteine",",","(","S",")","-2-amino-3-mercaptopropanoic","acid",",","which","occurs","naturally","in","firefly","luciferin","."),4241899). assertion_content_comment('oboGo_DCysteinedesulfhydraseactivity',s("Catalysis","of","the","reaction",":","D-cysteine","+","H2O","=","sulfide","+","NH3","+","pyruvate","."),4237488). assertion_content_comment('oboGo_DCysteinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-cysteine",",","(","S",")","-2-amino-3-mercaptopropanoic","acid",",","which","occurs","naturally","in","firefly","luciferin","."),4241896). assertion_content_comment('oboGo_Ddb1Ckn1complex',s("A","heterodimeric","nucleotide-excision","repair","complex","that","is","involved","in","transcription-coupled","repair",".","The","subunits","are","known","as","Ddb1","and","Ckn1","in","S",".","pombe",";","Ddb1","contains","a","motif","called","the","DDB-box","that","interacts","with","adaptor","proteins","for","DDB1/cullin","4","ubiquitin","ligases","."),4178324). assertion_content_comment('oboGo_Ddb1Wdr21complex',s("A","heterodimeric","nucleotide-excision","repair","complex","that","is","involved","in","transcription-coupled","repair",".","The","subunits","are","known","as","Ddb1","and","Wdr21","in","S",".","pombe",";","Ddb1","contains","a","motif","called","the","DDB-box","that","interacts","with","adaptor","proteins","for","DDB1/cullin","4","ubiquitin","ligases","."),4178315). assertion_content_comment('oboGo_DDehydroDGluconatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-dehydro-D-gluconate",",","the","anion","of","D-dehydro-D-gluconic","acid",",","an","aldonic","acid","derived","from","glucose","."),4351556). assertion_content_comment('oboGo_DDehydroDGluconatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-dehydro-D-gluconate",",","the","anion","of","D-dehydro-D-gluconic","acid",",","an","aldonic","acid","derived","from","glucose","."),4242407). assertion_content_comment('oboGo_DDehydroDGluconatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-dehydro-D-gluconate",",","the","anion","of","D-dehydro-D-gluconic","acid",",","an","aldonic","acid","derived","from","glucose","."),4242388). assertion_content_comment('oboGo_DDHeptose17Bisphosphatephosphataseactivity',s("Catalysis","of","the","reaction",":","D-beta-D-heptose","1",",","7-bisphosphate","+","H2O","=","D-beta-D-heptose","1-phosphate","+","phosphate","."),4359816). assertion_content_comment('oboGo_DDopachromedecarboxylaseactivity',s("Catalysis","of","the","reaction",":","D-dopachrome","+","H","(","+",")","=","5",",","6-dihydroxyindole","+","CO","(","2",")"),4344946). assertion_content_comment('oboGo_DDT23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","1",",","1",",","1-trichloro-2",",","2-bis-","(","4-chlorophenyl",")","ethane","+","O2","+","2","H","+","+","2","e-","=","cis-2",",","3-dihydrodiol","DDT",".","1",",","1",",","1-trichloro-2",",","2-bis-","(","4-chlorophenyl",")","ethane","is","also","known","as","DDT","."),4276813). assertion_content_comment('oboGo_DDTDehydrochlorinaseactivity',s("Catalysis","of","the","reaction",":","1",",","1",",","1-trichloro-2",",","2-bis","(","4-chlorophenyl",")","ethane","=","1",",","1-dichloro-2",",","2-bis","(","4-chlorophenyl",")","ethylene","+","chloride","+","H","(","+",")"),4273536). assertion_content_comment('oboGo_DeacetoxycephalosporinChydroxylaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","deacetoxycephalosporin","C","+","O","(","2",")","=","CO","(","2",")","+","deacetylcephalosporin","C","+","succinate","."),4299549). assertion_content_comment('oboGo_DeacetoxycephalosporinCsynthaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","O","(","2",")","+","penicillin","N","=","CO","(","2",")","+","deacetoxycephalosporin","C","+","H","(","2",")","O","+","succinate","."),4267799). assertion_content_comment('oboGo_DeacetylcephalosporinCacetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","deacetylcephalosporin","C","=","cephalosporin","C","+","CoA","."),4343014). assertion_content_comment('oboGo_Deacetyl_Citrate_Pro_3S_LyaseS_AcetyltransferaseActivity',s("Catalysis","of","the","reaction",":","deacetyl-","[","citrate-oxaloacetate-lyase","(","(","pro-3S",")","-CH","(","2",")","COO","(","-",")","-acetate",")","]","+","S-acetylphosphopantetheine","=","[","citrate","oxaloacetate-lyase","(","(","pro-3S",")","-CH","(","2",")","COO","(","-",")","-acetate",")","]","+","pantetheine","4","'","-phosphate","."),4366286). assertion_content_comment('oboGo_DeadenylationDependentdecappingofnuclearTranscribedmrna',s("Cleavage","of","the","5","'","-cap","of","a","nuclear","mRNA","triggered","by","shortening","of","the","poly","(","A",")","tail","to","below","a","minimum","functional","length","."),3974314). assertion_content_comment('oboGo_DeadenylationIndependentdecappingofnuclearTranscribedmrna',s("Cleavage","of","the","5","'","-cap","of","a","nuclear-transcribed","mRNA","that","is","independent","of","poly","(","A",")","tail","shortening","."),4319339). assertion_content_comment('oboGo_DEADHBoxrnahelicasebinding',s("Interacting","selectively","and","non-covalently","with","the","enzyme","DEAD/H-box","RNA","helicase","."),4257751). assertion_content_comment('oboGo_DeathDomainMediatedcomplexassembly',s("A","process","of","protein","complex","assembly","in","which","the","arrangement","and","bonding","together","of","the","set","of","components","that","form","the","protein","complex","is","mediated","by","a","death","domain","(","DD",")","interaction","."),4171346). assertion_content_comment('oboGo_DeathInducingsignalingcomplex',s("A","protein","complex","formed","by","the","association","of","signaling","proteins","with","a","death","receptor","upon","ligand","binding",".","The","complex","includes","procaspases","and","death","domain-containing","proteins","in","addition","to","the","ligand-bound","receptor","."),4320077). assertion_content_comment('oboGo_DeathReceptorAssociatedfactoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4215040). assertion_content_comment('oboGo_DecarboxylationDrivenactivetransmembranetransporteractivity',s("Primary","active","transport","of","a","solute","across","a","membrane","driven","by","decarboxylation","of","a","cytoplasmic","substrate",".","Primary","active","transport","is","catalysis","of","the","transport","of","a","solute","across","a","membrane",",","up","the","solute","'","s","concentration","gradient",",","by","binding","the","solute","and","undergoing","a","series","of","conformational","changes",".","Transport","works","equally","well","in","either","direction","and","is","driven","by","a","primary","energy","source","."),4291718). assertion_content_comment('oboGo_DeEtiolation',s("The","greening","response","of","plants","grown","in","the","dark","(","etiolated",")","as","a","result","of","chloroplast","biogenesis","and","the","accumulation","of","chlorophyll","."),4022637). assertion_content_comment('oboGo_DefenseResponseSignalingPathwayResistanceGeneDependent',s("A","series","of","molecular","signals","that","depends","upon","R-genes","and","is","activated","during","defense","response","."),4262205). assertion_content_comment('oboGo_DefenseResponseSignalingPathwayResistanceGeneIndependent',s("A","series","of","molecular","signals","that","is","activated","during","defense","response","and","does","not","depend","upon","R-genes","."),4335677). assertion_content_comment('oboGo_DefenseResponseToGramNegativebacterium',s("Reactions","triggered","in","response","to","the","presence","of","a","Gram-negative","bacterium","that","act","to","protect","the","cell","or","organism","."),4000787). assertion_content_comment('oboGo_DefenseResponseToGramPositivebacterium',s("Reactions","triggered","in","response","to","the","presence","of","a","Gram-positive","bacterium","that","act","to","protect","the","cell","or","organism","."),4000854). assertion_content_comment('oboGo_Dehydro_D_Arabinono_14_LactoneBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","dehydro-D-arabinono-1",",","4-lactone",",","the","gamma-lactone","(","5R",")","-3",",","4-dihydroxy-5-","(","hydroxymethyl",")","furan-2","(","5H",")","-one","."),4175816). assertion_content_comment('oboGo_Dehydro_D_Arabinono_14_LactoneMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","dehydro-D-arabinono-1",",","4-lactone",",","the","gamma-lactone","(","5R",")","-3",",","4-dihydroxy-5-","(","hydroxymethyl",")","furan-2","(","5H",")","-one","."),4175805). assertion_content_comment('oboGo_DehydroLGulonatedecarboxylaseactivity',s("Catalysis","of","the","reaction",":","3-dehydro-L-gulonate","+","H","(","+",")","=","L-xylulose","+","CO","(","2",")"),4374902). assertion_content_comment('oboGo_Delphinidin3OGlucosidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","delphinidin","3-O-glucoside",",","a","basic",",","water-soluble","anthocyanin","responsible","for","blue","coloration","of","flowers","and","fruits","."),4339291). assertion_content_comment('oboGo_Delta12Fattyaciddehydrogenaseactivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","linoleate","+","O","(","2",")","=","A","+","crepenynate","+","2","H","(","2",")","O","."),4301334). assertion_content_comment('oboGo_Delta14Sterolreductaseactivity',s("Catalysis","of","the","reaction",":","NADP","+","+","4",",","4-dimethyl-5-alpha-cholesta-8",",","24-dien-3-beta-ol","=","NADPH","+","H","+","+","4",",","4-dimethyl-5-alpha-cholesta-8",",","14",",","24-trien-3-beta-ol","."),4278087). assertion_content_comment('oboGo_Delta1_Piperideine_2_CarboxylateReductaseActivity',s("Catalysis","of","the","reaction",":","NADP","+","+","L-pipecolate","=","NADPH","+","delta1-piperideine-2-carboxylate","."),4365813). assertion_content_comment('oboGo_Delta1_Piperideine_6_CarboxylateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","delta1-piperideine-6-carboxylate","+","NAD","+","+","2","H2O","=","2-aminoadipate","+","NADH","+","H","+","Delta1-piperideine-6-carboxylate","is","also","known","as","2",",","3",",","4",",","5-tetrahydropyridine-2-carboxylate","."),4326604). assertion_content_comment('oboGo_Delta1_Pyrroline_5_CarboxylateSynthetaseActivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","+","NADPH","=","ADP","+","L-glutamate","gamma-semialdehyde","+","NADP","+","+","phosphate","."),4269114). assertion_content_comment('oboGo_Delta2424_1SterolReductaseActivity',s("Catalysis","of","the","reaction",":","ergosterol","+","NADP","(","+",")","=","ergosta-5",",","7",",","22",",","24","(","24","(","1",")",")","-tetraen-3beta-ol","+","H","(","+",")","+","NADPH","."),4346412). assertion_content_comment('oboGo_Delta24Sterolreductaseactivity',s("Catalysis","of","the","reaction",":","NADP","+","+","5-alpha-cholest-7-en-3-beta-ol","=","NADPH","+","H","+","+","5-alpha-cholesta-7",",","24-dien-3-beta-ol","."),4278101). assertion_content_comment('oboGo_Delta35Delta24DienoylCoaisomeraseactivity',s("Catalysis","of","the","isomerization","of","3",",","5-dienoyl-CoA","to","2",",","4-dienoyl-CoA","."),4279980). assertion_content_comment('oboGo_Delta3TransHexadecenoicacidphosphatidylglyceroldesaturaseactivity',s("Catalysis","of","the","reaction",":","1-18",":","3-3-16",":","0-phosphatidylglycerol","=","1-18",":","3-3-trans-16",":","1-phosphatidylglycerol","+","2","H","+","This","reaction","is","the","formation","of","a","trans","double","bond","between","carbon","3","and","carbon","4","(","counting","from","the","carboxyl","end",")","of","palmitic","acid",",","which","is","specifically","esterified","to","the","sn-2","glyceryl","carbon","of","phosphatidylglycerol","."),4191548). assertion_content_comment('oboGo_Delta4_3_Oxosteroid5beta_ReductaseActivity',s("Catalysis","of","the","reactions",":","(","1",")","5beta-cholestan-3-one","+","NADP","+","=","cholest-4-en-3-one","+","NADPH","+","H","+","and","(","2",")","17",",","21-dihydroxy-5beta-pregnane-3",",","11",",","20-trione","+","NADP","+","=","cortisone","+","NADPH","+","H","+"),4373846). assertion_content_comment('oboGo_Delta5Delta24DienoylCoaisomeraseactivity',s("Catalysis","of","the","isomerization","of","3",",","5-dienoyl-CoA","to","2",",","4-dienoyl-CoA","."),4255745). assertion_content_comment('oboGo_DeltaCadinenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","diphosphate","+","(","+",")","-delta-cadinene","."),4369568). assertion_content_comment('oboGo_DeltaCateninbinding',s("Interacting","selectively","and","non-covalently","with","the","delta","subunit","of","the","catenin","complex","."),4180265). assertion_content_comment('oboGo_DeltaDnapolymerasecofactorcomplex',s("OBSOLETE",".","A","complex","of","proteins","that","interacts","with","delta-DNA","polymerase",",","promoting","elongation",".","In","humans","it","is","a","heteropentamer","of","subunits","of","140/145",",","40",",","38",",","37","and","36.5","kDa",",","which","form","a","complex","with","the","proliferating","cell","nuclear","antigen","(","PCNA",")","in","the","presence","of","ATP","."),4220139). assertion_content_comment('oboGo_DeltaLAlphaAminoadipylLCysteinylDValinesynthetaseactivity',s("Catalysis","of","the","formation","of","delta-","(","L-alpha-aminoadipyl",")","-L-cysteinyl-D-valine","from","constituent","amino","acids","and","ATP","in","the","presence","of","magnesium","ions","and","dithioerythritol","."),4299527). assertion_content_comment('oboGo_DeltaOpioidreceptoractivity',s("Combining","with","an","opioid","to","initiate","a","change","in","cell","activity",",","with","the","pharmacological","characteristics","of","delta-opioid","receptors",",","including","the","activity","of","enkephalins","as","ligands","."),4198931). assertion_content_comment('oboGo_DeltaTocopherolcyclaseactivity',s("Catalysis","of","the","reaction",":","2-methyl-6-phytyl-1",",","4-benzoquinone","=","delta-tocopherol","."),4190971). assertion_content_comment('oboGo_DeltaTypeopioidreceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","delta-type","opioid","receptor","."),4323991). assertion_content_comment('oboGo_DemethylmacrocinOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","demethylmacrocin","=","S-adenosyl-L-homocysteine","+","H","(","+",")","+","macrocin","."),4308518). assertion_content_comment('oboGo_Demethylsterigmatocystin6OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","6-demethylsterigmatocystin","+","S-adenosyl-L-methionine","=","sterigmatocystin","+","S-adenosyl-homocysteine","."),4365434). assertion_content_comment('oboGo_DendriteSelfAvoidance',s("The","process","in","which","dendrites","recognize","and","avoid","contact","with","sister","dendrites","from","the","same","cell","."),4175062). assertion_content_comment('oboGo_DeNovoGDPLFucosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-L-fucose","from","GDP-D-mannose","via","GDP-4-dehydro-6-deoxy-D-mannose",",","requiring","the","functions","of","GDP-mannose","4",",","6-dehydratase","(","EC",":","4.2.1.47",")","and","GDP-L-fucose","synthase","(","EC",":","1.1.1.271",")"),4313076). assertion_content_comment('oboGo_DeNovoLMethioninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine",",","the","L-enantiomer","of","(","2S",")","-2-amino-4-","(","methylsulfanyl",")","butanoic","acid",",","from","simpler","components","."),4166607). assertion_content_comment('oboGo_Deoxycytidylate5Hydroxymethyltransferaseactivity',s("Catalysis","of","the","reaction",":","5",",","10-methylenetetrahydrofolate","+","dCMP","+","H","(","2",")","O","=","(","6S",")","-5",",","6",",","7",",","8-tetrahydrofolate","+","5-hydroxymethyldeoxycytidylate","."),4365392). assertion_content_comment('oboGo_DeoxycytidylateCMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","5",",","10-methylenetetrahydrofolate","+","dCMP","=","2","'","-deoxy-5-methyl-5","'","-cytidylate","+","7",",","8-dihydrofolate","."),4270430). assertion_content_comment('oboGo_DeoxyhypusineSynthaseActivity_4',s("Catalysis","of","the","reaction",":","[","eIF5A-precursor","]","-lysine","+","spermidine","=","[","eIF5A-precursor","]","-deoxyhypusine","+","propane-1",",","3-diamine",".","Four","sub-reactions","have","been","identified",",","in","which","the","intermediates","remain","tightly","associated","with","the","enzyme",":","spermidine","+","NAD","+","=","dehydrospermidine","+","NADH",";","dehydrospermidine","+","[","enzyme","]","-lysine","=","N-","(","4-aminobutylidene",")","-","[","enzyme","]","-lysine","+","propane-1",",","3-diamine",";","N-","(","4-aminobutylidene",")","-","[","enzyme","]","-lysine","+","[","eIF5A-precursor","]","-lysine","=","N-","(","4-aminobutylidene",")","-","[","eIF5A-precursor","]","-lysine","+","[","enzyme","]","-lysine",";","N-","(","4-aminobutylidene",")","-","[","eIF5A-precursor","]","-lysine","+","NADH","+","H","+","=","[","eIF5A-precursor","]","-deoxyhypusine","+","NAD","+"),4210948). assertion_content_comment('oboGo_DeoxylimonateARingLactonaseactivity',s("Catalysis","of","the","reaction",":","deoxylimonoate","+","H","(","2",")","O","=","deoxylimononate","D-ring-lactone","+","H","(","+",")"),4374882). assertion_content_comment('oboGo_DeoxyNucleosidePhosphatekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","deoxynucleoside","phosphate","=","ADP","+","deoxynucleoside","diphosphate","."),4371603). assertion_content_comment('oboGo_Deoxynucleotide3Phosphataseactivity',s("Catalysis","of","the","reaction",":","a","deoxynucleoside","3","'","-phosphate","+","H2O","=","a","deoxynucleoside","+","phosphate","."),4376442). assertion_content_comment('oboGo_DeoxyribodipyrimidinePhotoLyaseactivity',s("Catalysis","of","the","reaction",":","cyclobutadipyrimidine","(","in","DNA",")","=","2","pyrimidine","residues","(","in","DNA",")","This","reaction","represents","the","reactivation","of","irradiated","DNA","by","light","."),4183920). assertion_content_comment('oboGo_DeoxyribonucleaseIVPhageT4Inducedactivity',s("Catalysis","of","the","endonucleolytic","cleavage","to","5","'","-phosphooligonucleotide","end-products","."),4250361). assertion_content_comment('oboGo_Deoxyribonucleoside5MonophosphatenGlycosidaseactivity',s("Catalysis","of","the","reaction",":","a","deoxyribonucleoside","5","'","-monophosphate","+","H2O","=","deoxyribose","5-monophosphate","+","a","purine","or","pyrimidine","base","."),4177513). assertion_content_comment('oboGo_Deoxyribose15Bisphosphatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","deoxyribose","1",",","5-bisphosphate",",","the","diphosphorylated","sugar","1",",","5-diphospho-2-deoxyribose","."),4225389). assertion_content_comment('oboGo_Deoxyribose15Bisphosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","deoxyribose","1",",","5-bisphosphate",",","the","diphosphorylated","sugar","1",",","5-diphospho-2-deoxyribose","."),4225386). assertion_content_comment('oboGo_Deoxyribose5Phosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","deoxyribose","5-phosphate",",","the","phosphorylated","sugar","5-phospho-2-deoxyribose","."),4225441). assertion_content_comment('oboGo_Deoxyribose5Phosphatephosphorylation',s("The","process","of","introducing","a","phosphate","group","into","deoxyribose","5-phosphate","to","produce","deoxyribose","bisphosphate","."),4225445). assertion_content_comment('oboGo_DeoxyribosePhosphatealdolaseactivity',s("Catalysis","of","the","reaction",":","2-deoxy-D-ribose","5-phosphate","=","D-glyceraldehyde","3-phosphate","+","acetaldehyde","."),4211784). assertion_content_comment('oboGo_DephosphoCoakinaseactivity',s("Catalysis","of","the","reaction",":","3","'","-dephospho-CoA","+","ATP","=","ADP","+","CoA","+","2","H","(","+",")"),4211176). assertion_content_comment('oboGo_DephosphoReductasekinasekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","dephospho-","[","[","hydroxymethylglutaryl-CoA","reductase","(","NADPH",")","]","kinase","]","=","ADP","+","[","[","hydroxymethylglutaryl-CoA","reductase","(","NADPH",")","]","kinase","]"),4376409). assertion_content_comment('oboGo_DephosphorylationGatedchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","solute","by","a","channel","that","opens","in","response","to","dephosphorylation","of","one","of","its","constituent","parts","."),4333126). assertion_content_comment('oboGo_DephosphorylationOfRNAPolymeraseIICTerminaldomain',s("The","process","of","removing","a","phosphate","group","from","an","amino","acid","residue","in","the","C-terminal","domain","of","RNA","polymerase","II",".","Some","dephosphorylation","occurs","during","transcription","while","some","may","occur","after","the","enzyme","is","released","from","the","template","in","order","to","prepare","it","for","the","beginning","of","the","transcription","cycle","again",".","RNA","polymerase","II","with","little","or","no","phosphorylation","is","referred","to","as","the","hypophosphorylated","or","II","(","A",")","form","."),4177893). assertion_content_comment('oboGo_DErythroSphingosinekinaseactivity',s("Catalysis","of","the","reaction",":","sphingosine","+","ATP","=","sphingosine","1-phosphate","+","ADP","."),4269591). assertion_content_comment('oboGo_Desacetoxyvindoline4Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","desacetoxyvindoline","+","2-oxoglutarate","+","O2","=","desacetylvindoline","+","succinate","+","CO2","."),4268007). assertion_content_comment('oboGo_DesensitizationOfGProteincoupledreceptorproteinsignalingpathwaybyarrestin',s("The","process","that","inhibits","the","signaling","function","of","a","G-protein","coupled","receptor","by","uncoupling","the","receptor","from","its","downstream","G","proteins","."),4374205). assertion_content_comment('oboGo_DesensitizationOfGProteincoupledreceptorproteinsignalingpathway',s("The","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","G-protein","coupled","receptor","protein","signaling","pathway","activity","after","prolonged","stimulation","with","an","agonist","of","the","pathway","."),3991230). assertion_content_comment('oboGo_DetectionOfDNADamageStimulusInvolvedInIntraSdnadamagecheckpoint',s("The","series","of","events","in","which","information","about","damage","to","DNA","is","received","and","converted","into","a","molecular","signal",",","contributing","to","an","intra-S","DNA","damage","checkpoint","."),4128247). assertion_content_comment('oboGo_DetectionOfStimulusInvolvedInSMcheckpoint',s("The","series","of","events","in","which","information","about","whether","DNA","replication","is","complete","is","received","and","converted","into","a","molecular","signal",",","contributing","to","an","S-M","checkpoint","."),4127898). assertion_content_comment('oboGo_DetoxificationOfArsenicContainingsubstance',s("Any","process","that","reduces","or","removes","the","toxicity","of","compounds","containing","arsenic",",","including","arsenates",",","arsenites",",","and","arsenides",".","These","include","transport","of","such","compounds","away","from","sensitive","areas","and","to","compartments","or","complexes","whose","purpose","is","sequestration","of","arsenic","or","arsenic-containing","compounds","."),4170072). assertion_content_comment('oboGo_Dextran16AlphaIsomaltotriosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","6-alpha-D-glucosidic","linkages","in","dextrans",",","to","remove","successive","isomaltotriose","units","from","the","non-reducing","ends","of","the","chains","."),4344691). assertion_content_comment('oboGo_DFuconatedehydrataseactivity',s("Catalysis","of","the","reaction",":","D-fuconate","=","2-dehydro-3-deoxy-D-fuconate","+","H","(","2",")","O","."),4375208). assertion_content_comment('oboGo_DGalactaratebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-galactarate",",","the","D-enantiomer","of","the","anion","of","galactaric","acid","."),4315325). assertion_content_comment('oboGo_DGalactaratecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-galactarate",",","the","D-enantiomer","of","the","anion","of","galactaric","acid","."),4243124). assertion_content_comment('oboGo_DGalactaratemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-galactarate",",","the","D-enantiomer","of","galactarate",",","the","anion","of","galactaric","acid","."),4243121). assertion_content_comment('oboGo_DGalactaratetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-galactarate",",","the","D-enantiomer","of","the","anion","of","galactaric","acid",",","from","one","side","of","the","membrane","to","the","other","."),4315037). assertion_content_comment('oboGo_DGalactaratetransport',s("The","directed","movement","of","D-galactarate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","D-galactarate","is","the","D-enantiomer","of","galactarate",",","the","anion","of","galactaric","acid","."),4315299). assertion_content_comment('oboGo_DGalactonatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-galactonate",",","the","anion","of","D-galactonic","acid","."),4359456). assertion_content_comment('oboGo_DGalactonatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-galactonate",",","the","anion","of","D-galactonic","acid","."),4359391). assertion_content_comment('oboGo_DGalactonatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-galactonate",",","the","D-enantiomer","of","galactonate",",","from","one","side","of","the","membrane","to","the","other","."),4315007). assertion_content_comment('oboGo_DGalactonatetransport',s("The","directed","movement","of","D-galactonate",",","the","D-enantiomer","of","galactonate",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4315056). assertion_content_comment('oboGo_D_Galactose_1_PhosphatePhosphataseActivity',s("Catalysis","of","the","reaction",":","D-galactose-1-phosphate","+","H2O","=","D-galactose","+","phosphate","."),4176042). assertion_content_comment('oboGo_DGalacturonatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-galacturonate",",","the","D-enantiomer","of","galacturonate",",","the","anion","of","galacturonic","acid","."),4339360). assertion_content_comment('oboGo_DGalacturonatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-galacturonate",",","the","D-enantiomer","of","galacturonate",",","the","anion","of","galacturonic","acid","."),4244520). assertion_content_comment('oboGo_DGalacturonatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-galacturonate",",","the","D-enantiomer","of","galacturonate",",","the","anion","of","galacturonic","acid",".","D-galacturonic","acid","is","a","component","of","plant","gums","and","bacterial","cell","walls","."),4244500). assertion_content_comment('oboGo_DGlucaratebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-glucarate",",","the","D-enantiomer","of","glucarate","."),4315249). assertion_content_comment('oboGo_DGlucaratecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-glucarate",",","the","D-enantiomer","of","glucarate","."),4315275). assertion_content_comment('oboGo_DGlucaratemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-glucarate",",","the","D-enantiomer","of","glucarate",".","D-glucarate","is","derived","from","either","D-glucose","or","L-gulose","."),4315244). assertion_content_comment('oboGo_DGlucaratetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-glucarate",",","the","D-enantiomer","of","glucarate",",","from","one","side","of","the","membrane","to","the","other","."),4315027). assertion_content_comment('oboGo_DGlucaratetransport',s("The","directed","movement","of","D-glucarate",",","the","D-enantiomer","of","glucarate",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4315289). assertion_content_comment('oboGo_DGluconatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-gluconate",",","the","anion","of","D-gluconic","acid",",","the","aldonic","acid","derived","from","glucose","."),4351527). assertion_content_comment('oboGo_DGluconatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-gluconate",",","the","anion","of","D-gluconic","acid",",","the","aldonic","acid","derived","from","glucose","."),4351542). assertion_content_comment('oboGo_DGluconatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-gluconate",",","the","anion","of","D-gluconic","acid",",","the","aldonic","acid","derived","from","glucose","."),4242524). assertion_content_comment('oboGo_DGlucose_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","D-glucose","+","H","+","=","D-glucose","+","H","+","Symporter","activity","enables","the","active","transport","of","a","solute","across","a","membrane","by","a","mechanism","whereby","two","or","more","species","are","transported","together","in","the","same","direction","in","a","tightly","coupled","process","not","directly","linked","to","a","form","of","energy","other","than","chemiosmotic","energy",".","D-glucose","is","the","dextrorotatory","D-enantiomer","of","glucose","."),4221940). assertion_content_comment('oboGo_DGlucosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","the","D-enantiomer","of","the","hexose","monosaccharide","glucose","from","one","side","of","the","membrane","to","the","other","."),4221930). assertion_content_comment('oboGo_DGlucuronatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-glucuronate",",","the","D-enantiomer","of","glucuronate","."),4315192). assertion_content_comment('oboGo_DGlucuronatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-glucuronate",",","the","D-enantiomer","of","glucuronate","."),4315222). assertion_content_comment('oboGo_DGlucuronatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-glucuronate",",","the","D-enantiomer","of","glucuronate","."),4315188). assertion_content_comment('oboGo_DGlucuronatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-glucuronate",",","the","D-enantiomer","of","glucuronate",",","from","one","side","of","the","membrane","to","the","other","."),4315017). assertion_content_comment('oboGo_DGlucuronatetransport',s("The","directed","movement","of","D-glucuronate",",","the","D-enantiomer","of","glucuronate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4315046). assertion_content_comment('oboGo_DGlutamatecyclaseactivity',s("Catalysis","of","the","reaction",":","D-glutamate","=","5-oxo-D-proline","+","H","(","2",")","O","."),4375173). assertion_content_comment('oboGo_DGlutamatedAspartateoxidaseactivity',s("Catalysis","of","the","reaction",":","D-glutamate","+","H2O","+","O2","=","2-oxoglutarate","+","NH3","+","H2O2","."),4375196). assertion_content_comment('oboGo_DGlutamatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-glutamate",",","the","D-enantiomer","of","the","amino","acid","glutamate",",","i.e",".","(","2R",")","-2-aminopentanedioic","acid","."),4347224). assertion_content_comment('oboGo_DGlutamateoxidaseactivity',s("Catalysis","of","the","reaction",":","D-glutamate","+","H2O","+","O2","=","2-oxoglutarate","+","NH3","+","H2O2",";","D-aspartate","+","H2O","=","oxaloacetate","+","NH3","+","H2O2","."),4375184). assertion_content_comment('oboGo_DGlutaminaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","L-glutamine","=","NH3","+","D-glutamate","."),4270487). assertion_content_comment('oboGo_DGlutaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-glutamine",",","the","D-enantiomer","of","the","amino","acid","glutamine",",","i.e",".","(","2R",")","-2",",","5-diamino-5-oxopentanoic","acid","."),4347276). assertion_content_comment('oboGo_DGlutamyltransferaseactivity',s("Catalysis","of","the","reaction",":","L","(","or","D",")","-glutamine","+","D-glutamyl-peptide","=","NH3","+","5-glutamyl-D-glutamyl-peptide","."),4375160). assertion_content_comment('oboGo_DiacetylReductaseRAcetoinformingactivity',s("Catalysis","of","the","reaction",":","(","R",")","-acetoin","+","NAD","(","+",")","=","diacetyl","+","H","(","+",")","+","NADH","."),4186709). assertion_content_comment('oboGo_DiacetylReductaseSAcetoinformingactivity',s("Catalysis","of","the","reaction",":","(","S",")","-acetoin","+","NAD","(","+",")","=","diacetyl","+","H","(","+",")","+","NADH","."),4186719). assertion_content_comment('oboGo_DiacylglycerolOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","1",",","2-diacylglycerol","=","CoA","+","triacylglycerol","."),4211214). assertion_content_comment('oboGo_DiacylglycerolSteroloAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","sterol","+","1",",","2-diacylglycerol","=","sterol","ester","+","acylglycerol","."),4366190). assertion_content_comment('oboGo_DiamineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","an","alkane-alpha",",","omega-diamine","=","CoA","+","an","N-acetyldiamine","."),4211190). assertion_content_comment('oboGo_Diaminobutyrate_2_OxoglutarateTransaminaseActivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-2",",","4-diaminobutyrate","=","L-aspartate","4-semialdehyde","+","L-glutamate","."),4298422). assertion_content_comment('oboGo_DiaminobutyratePyruvatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-2",",","4-diaminobutyrate","+","pyruvate","=","L-alanine","+","L-aspartate","4-semialdehyde","."),4368934). assertion_content_comment('oboGo_DiaminopropionateAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","2",",","3-diaminopropionate","+","H2O","=","pyruvate","+","2","NH3","."),4250347). assertion_content_comment('oboGo_Dibenzofuran44aDioxygenaseactivity',s("Catalysis","of","the","reaction",":","dibenzofuran","+","NADH","+","H","+","+","O2","=","2",",","2","'",",","3-trihydroxybiphenyl","+","NAD","+"),4276832). assertion_content_comment('oboGo_DibenzoPDioxincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","dibenzo-p-dioxin",",","a","substance","composed","of","two","benzene","rings","linked","by","two","ether","bonds","."),4240258). assertion_content_comment('oboGo_DibenzoPDioxinmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","dibenzo-p-dioxin",",","a","substance","composed","of","two","benzene","rings","linked","by","two","ether","bonds",".","Dibenzo-p-dioxins","are","generated","as","by-products","in","the","manufacturing","of","herbicides",",","insecticides",",","fungicides",",","paper","pulp","bleaching",",","and","in","incineration",",","and","can","accumulate","in","milk","and","throughout","the","food","chain",",","creating","significant","health","concern","."),4240248). assertion_content_comment('oboGo_Dibenzothiophene_55_DioxideMonooxygenaseActivity',s("Catalysis","of","the","reaction",":","dibenzothiophene-5",",","5-dioxide","+","O2","+","2","NADH","+","H","+","=","2","NAD","+","+","H2O","+","2","'","-hydroxybiphenyl-2-sulfinate","."),4276476). assertion_content_comment('oboGo_DicarboxylateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","an","omega-dicarboxylic","acid","=","AMP","+","diphosphate","+","an","omega-carboxyacyl-CoA","."),4376523). assertion_content_comment('oboGo_DiclusterBacterialTypeferredoxin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259527). assertion_content_comment('oboGo_DicoumaroylMonocaffeoylSpermidineMetaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","dicoumaroyl","monocaffeoyl","spermidine","+","NADPH","+","O2","=","monocoumaroyl","dicaffeoyl","spermidine","+","NADP","+","+","H2O","."),4157130). assertion_content_comment('oboGo_DIditol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-iditol","+","NAD","+","=","D-sorbose","+","NADH","."),4374731). assertion_content_comment('oboGo_Diethyl2_Methyl_3_OxosuccinateReductaseActivity',s("Catalysis","of","the","reaction",":","diethyl","(","2R",",","3R",")","-2-methyl-3-hydroxysuccinate","+","NADP","(","+",")","=","diethyl","2-methyl-3-oxosuccinate","+","H","(","+",")","+","NADPH","."),4364328). assertion_content_comment('oboGo_DIF_1BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1-","(","3",",","5-dichloro-2",",","6-dihydroxy-4-methoxyphenyl",")","hexan-1-one",",","also","known","as","DIF-1",",","differentiation-inducing","factor-1",".","DIF-1","is","a","secreted","chlorinated","molecule","that","controls","cell","fate","during","development","of","Dictyostelium","cells","."),4318870). assertion_content_comment('oboGo_DiferricTransferrinreductaseactivity',s("Catalysis","of","the","reaction",":","transferrin","[","Fe2","+","]","2","+","NAD","+","=","transferrin","[","Fe3","+","]","2","+","NADH","."),4376510). assertion_content_comment('oboGo_DiferuloylMonoHydroxyferuloylspermidinemetaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","diferuloyl","mono-","(","hydroxyferuloyl",")","spermidine","+","NADPH","+","O2","=","monoferuloyl","di-","(","hydroxyferuloyl",")","spermidine","+","NADP","+","+","H2O","."),4156945). assertion_content_comment('oboGo_DifructoseAnhydridesynthaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","bis-D-fructose","2","'",",","1",":","2",",","1","'","-dianhydride","=","inulobiose","."),4376499). assertion_content_comment('oboGo_Dihydrochelirubine12Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","dihydrochelirubine","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","12-hydroxydihydrochelirubine","+","H","(","2",")","O","+","NADP","(","+",")"),4364959). assertion_content_comment('oboGo_Dihydrokaempferol4Reductaseactivity',s("Catalysis","of","the","reaction",":","cis-3",",","4-leucopelargonidin","+","NADP","+","=","(","+",")","-dihydrokaempferol","+","NADPH","+","H","+"),4299408). assertion_content_comment('oboGo_DihydrolipoamideSAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","dihydrolipoamide","=","CoA","+","S-acyldihydrolipoamide","."),4201173). assertion_content_comment('oboGo_DihydrolipoamideSAcyltransferasecomplex',s("OBSOLETE",".","An","enzyme","complex","that","catalyzes","the","transfer","of","an","acyl","group","from","coenzyme","A","to","dihydrolipoamide","."),4260237). assertion_content_comment('oboGo_DihydrolipoamideSSuccinyltransferasecomplex',s("OBSOLETE",".","An","enzyme","complex","that","catalyzes","the","transfer","of","succinyl-CoA","to","dihydrolipoamide","to","form","S-succinyldihydrolipoamide",".","The","enzyme","is","a","component","of","the","multienzyme","2-oxoglutarate","dehydrogenase","complex","."),4260171). assertion_content_comment('oboGo_DihydrolipoylDehydrogenaseComplex_7',s("OBSOLETE",".","Complex","that","possesses","dihydrolipoyl","dehydrogenase","activity","."),4260159). assertion_content_comment('oboGo_DihydrolipoyllysineResidue2Methylpropanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","2-methylpropanoyl-CoA","+","enzyme","N6-","(","dihydrolipoyl",")","lysine","=","CoA","+","enzyme","N6-","(","S-","[","2-methylpropanoyl","]","dihydrolipoyl",")","lysine","."),4326142). assertion_content_comment('oboGo_DihydrolipoyllysineResidueacetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","dihydrolipoamide","=","CoA","+","S-acetyldihydrolipoamide","."),4201175). assertion_content_comment('oboGo_DihydrolipoyllysineResiduesuccinyltransferaseactivity',s("Catalysis","of","the","reaction",":","succinyl-CoA","+","dihydrolipoamide","=","CoA","+","S-succinyldihydrolipoamide","."),4211072). assertion_content_comment('oboGo_DihydroneopterinTriphosphate2Epimeraseactivity',s("Catalysis","of","the","reaction",":","dihydroneopterin","triphosphate","=","dihydromonapterin-triphosphate","."),4252316). assertion_content_comment('oboGo_Dihydrosanguinarine10Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","dihydrosanguinarine","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","10-hydroxydihydrosanguinarine","+","H","(","2",")","O","+","NADP","(","+",")"),4364970). assertion_content_comment('oboGo_Dihydrosphingosine_1_PhosphatePhosphataseActivity',s("Catalysis","of","the","reaction",":","dihydrosphingosine","1-phosphate","+","H2O","=","dihydrosphingosine","+","phosphate","."),4176363). assertion_content_comment('oboGo_Dihydrosphingosine_1_PPathway',s("A","phosphatidylethanolamine","biosynthetic","process","that","proceeds","via","the","enzymatic","action","of","dihydrosphingosine","phosphate","lyase","."),4230421). assertion_content_comment('oboGo_Dihydrostreptomycin_6_Phosphate3_Alpha_KinaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","dihydrostreptomycin","6-phosphate","=","ADP","+","dihydrostreptomycin","3","'","alpha",",","6-bisphosphate","+","2","H","(","+",")"),4368321). assertion_content_comment('oboGo_Dihydrotestosterone17BetaDehydrogenaseactivity',s("Catalysis","of","the","reaction",":","5alpha-dihydrotestosterone","+","NAD","+","=","5alpha-androstane-3",",","17-dione","+","NADH","."),4376629). assertion_content_comment('oboGo_DihydroxyAciddehydrataseactivity',s("Catalysis","of","the","reaction",":","2",",","3-dihydroxy-3-methylbutanoate","=","3-methyl-2-oxobutanoate","+","H2O","."),4210773). assertion_content_comment('oboGo_DihydroxyphenylalanineAmmoniaLyaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","3",",","4-dihydroxy-L-phenylalanine","=","trans-caffeate","+","NH3","."),4376608). assertion_content_comment('oboGo_DiisopropylFluorophosphataseactivity',s("Catalysis","of","the","reaction",":","diisopropyl","fluorophosphate","+","H","(","2",")","O","=","diisopropyl","phosphate","+","2","H","(","+",")","+","hydrogen","fluoride","."),4376723). assertion_content_comment('oboGo_DimethylanilineNOxidealdolaseactivity',s("Catalysis","of","the","reaction",":","N",",","N-dimethylaniline","N-oxide","=","N-methylaniline","+","formaldehyde","."),4376652). assertion_content_comment('oboGo_DimethylationInvolvedInSSURrnamaturation',s("Dimethylation","of","the","N6","amino","groups","of","two","consecutive","adenosine","residues","near","the","3","'","-end","of","the","SSU","rRNA",".","This","process","has","been","conserved","from","bacteria","to","eukaryotes","."),3976357). assertion_content_comment('oboGo_DimethylhistidineNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","NN1",",","NN1-dimethyl-L-histidine","=","S-adenosyl-L-homocysteine","+","NN1",",","NN1",",","NN1-trimethyl-L-histidine","."),4308746). assertion_content_comment('oboGo_DiNButyltindioxygenaseactivity',s("Catalysis","of","the","reaction",":","dibutyltin","+","O2","+","2","H","+","+","2","e-","=","H2O","+","beta-hydroxybutylbutyltin","."),4275367). assertion_content_comment('oboGo_DinitrosylIroncomplexbinding',s("Interacting","selectively","and","non-covalently","with","a","dinitrosyl-iron","complex",".","Nitric","oxide","(","NO",")","is","stored","as","dinitrosyl-iron","complexes",",","which","form","spontaneously","from","Glutathione","(","GSH",")",",","S-nitrosoglutathione",",","and","trace","amounts","of","ferrous","ions","."),4380845). assertion_content_comment('oboGo_DipeptidylPeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","N-terminal","dipeptides","from","a","polypeptide","chain","."),4209299). assertion_content_comment('oboGo_DipeptidylPeptidaseandtripeptidylPeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","hydrolysis","of","N-terminal","di-","or","tripeptides","from","a","polypeptide","chain","."),4301624). assertion_content_comment('oboGo_DipeptidylPeptidaseiactivity',s("OBSOLETE",".","Catalysis","of","the","release","of","an","N-terminal","dipeptide",",","Xaa-Xbb","from","Xaa-Xbb-Xcc",",","except","when","Xaa","is","Arg","or","Lys",",","or","Xbb","or","Xcc","is","Pro","."),4209302). assertion_content_comment('oboGo_DipeptidylPeptidaseiiiactivity',s("OBSOLETE",".","Catalysis","of","the","release","of","an","N-terminal","dipeptide","from","a","peptide","comprising","four","or","more","residues",",","with","broad","specificity",";","also","acts","on","dipeptidyl","2-naphthylamides","."),4268517). assertion_content_comment('oboGo_DipeptidylPeptidaseivactivity',s("OBSOLETE",".","Catalysis","of","the","release","of","an","N-terminal","dipeptide",",","by","the","hydrolysis","of","the","Xbb-Xcc","bond","in","Xaa-Xbb-Xcc",",","preferentially","when","Xbb","is","Pro",",","provided","Xcc","is","neither","Pro","nor","hydroxyproline","."),4209423). assertion_content_comment('oboGo_DiphenylEther12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","diphenyl","ether","+","NADH","+","O2","+","H","+","=","phenol","+","catechol","+","NAD","+"),4348678). assertion_content_comment('oboGo_DiphenylEther23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","diphenyl","ether","+","O2","=","2",",","3-dihydroxydiphenyl","ether","."),4348696). assertion_content_comment('oboGo_Diphosphate_Fructose_6_Phosphate1_PhosphotransferaseActivity',s("Catalysis","of","the","reaction",":","fructose-6-phosphate","+","diphosphate","=","phosphate","+","fructose-1",",","6-bisphosphate","."),4368302). assertion_content_comment('oboGo_DiphosphateGlycerolphosphotransferaseactivity',s("Catalysis","of","the","reaction",":","diphosphate","+","glycerol","=","glycerol","1-phosphate","+","H","(","+",")","+","phosphate","."),4368262). assertion_content_comment('oboGo_DiphosphateProteinphosphotransferaseactivity',s("Catalysis","of","the","reaction",":","microsomal-membrane","protein","+","diphosphate","=","diphosphate","+","O-phospho-microsomal-membrane","protein","."),4368997). assertion_content_comment('oboGo_DiphosphatePurinenucleosidekinaseactivity',s("Catalysis","of","the","reaction",":","diphosphate","+","a","purine","nucleoside","=","monophosphate","+","a","purine","mononucleotide","."),4249974). assertion_content_comment('oboGo_DiphosphateSerinephosphotransferaseactivity',s("Catalysis","of","the","reaction",":","L-serine","+","diphosphate","=","O-phospho-L-serine","+","H","(","+",")","+","phosphate","."),4368335). assertion_content_comment('oboGo_DiphosphoinositolPentakisphosphatekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","1D-myo-inositol","5-diphosphate","pentakisphosphate","=","ADP","+","1D-myo-inositol","bisdiphosphate","tetrakisphosphate","."),4343784). assertion_content_comment('oboGo_DiphosphoinositolPolyphosphatediphosphataseactivity',s("Catalysis","of","the","reaction",":","diphospho-myo-inositol","polyphosphate","+","H2O","=","myo-inositol","polyphosphate","+","phosphate","."),4254343). assertion_content_comment('oboGo_DiphthineAmmonialigaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","diphthine","+","NH","(","4",")","(","+",")","=","ADP","+","diphthamide","+","2","H","(","+",")","+","phosphate","."),4258280). assertion_content_comment('oboGo_DiscoidalHighDensitylipoproteinparticle',s("A","newly","formed","high-density","lipoprotein","particle",";","consists","of","a","phospholipid","bilayer","surrounded","by","two","or","more","APOA1","molecules",".","The","discoidal","HDL","particle","is","formed","when","lipid-free","or","lipid-poor","APOA1","acquires","phospholipids","and","unesterified","cholesterol","from","either","cell","membranes","or","triglyceride-rich","lipoproteins","(","undergoing","lipolysis","by","lipoprotein","lipase",")"),4355773). assertion_content_comment('oboGo_Disulfoglucosamine_6_SulfataseActivity',s("Catalysis","of","the","reaction",":","N","(","2",")",",","6-disulfo-D-glucosamine","+","H","(","2",")","O","=","N-sulfo-D-glucosamine","+","H","(","+",")","+","sulfate","."),4376181). assertion_content_comment('oboGo_DiTranspolyCisDecaprenylcistransferaseactivity',s("Catalysis","of","the","reaction",":","di-trans-poly-cis-decaprenyl","diphosphate","+","isopentenyl","diphosphate","=","diphosphate","+","di-trans-poly-cis-undecaprenyl","diphosphate","."),4250422). assertion_content_comment('oboGo_DiTriValentinorganicanionhomeostasis',s("OBSOLETE",".","Any","process","involved","in","the","maintenance","of","an","internal","steady","state","of","divalent","or","trivalent","inorganic","anions","within","an","organism","or","cell","."),4222000). assertion_content_comment('oboGo_DiTriValentinorganiccationhomeostasis',s("OBSOLETE",".","Any","process","involved","in","the","maintenance","of","an","internal","steady","state","of","divalent","or","trivalent","cations","within","an","organism","or","cell","."),4222032). assertion_content_comment('oboGo_DivinylChlorophyllideA8VinylReductaseactivity',s("Catalysis","of","the","reaction",":","chlorophyllide","a","+","NADP","+","=","divinyl","chlorophyllide","a","+","NADPH","+","H","+"),4342518). assertion_content_comment('oboGo_DL_2HaloacidDehalogenaseActivity',s("Catalysis","of","the","reaction",":","trichloroacetate","+","2","H2O","=","3","H","+","+","3","Cl-","+","oxalate","."),4274434). assertion_content_comment('oboGo_D_Lactate_2_SulfataseActivity',s("Catalysis","of","the","reaction",":","(","R",")","-2-O-sulfolactate","+","H","(","2",")","O","=","(","R",")","-lactate","+","H","(","+",")","+","sulfate","."),4374719). assertion_content_comment('oboGo_DLactatebiosyntheticprocessfrommethylglyoxalviarLactaldehyde',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-lactate","from","other","compounds",",","including","methylglyoxal",",","via","the","intermediate","(","R",")","-lactaldehyde","."),4238512). assertion_content_comment('oboGo_DLactatebiosyntheticprocessfrompyruvate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D","(","-",")","-lactate","from","other","compounds",",","including","pyruvate","."),4238438). assertion_content_comment('oboGo_DLactatedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-lactate","+","NAD","(","+",")","=","H","(","+",")","+","NADH","+","pyruvate","."),4252230). assertion_content_comment('oboGo_DLactatedehydrogenasecytochromeactivity',s("Catalysis","of","the","reaction",":","(","R",")","-lactate","+","2","ferricytochrome","c","=","pyruvate","+","2","ferrocytochrome","c","."),4206920). assertion_content_comment('oboGo_D_LactateDehydrogenaseCytochromeC_553Activity',s("Catalysis","of","the","reaction",":","2","ferricytochrome","C-553","+","D-lactate","=","2","ferrocytochrome","C-553","+","pyruvate","."),4364872). assertion_content_comment('oboGo_DLysine56Aminomutaseactivity',s("Catalysis","of","the","reaction",":","D-lysine","=","2",",","5-diaminohexanoate","."),4374755). assertion_content_comment('oboGo_DLysinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-lysine",",","the","D-enantiomer","of","lysine",";","i.e",".","(","2R",")","-2",",","6-diaminohexanoic","acid","."),4241318). assertion_content_comment('oboGo_DLysinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-lysine",",","the","D-enantiomer","of","lysine",";","i.e",".","(","2R",")","-2",",","6-diaminohexanoic","acid","."),4241315). assertion_content_comment('oboGo_DLysineoxidaseactivity',s("Catalysis","of","the","reaction",":","D-lysine","+","O2","+","H2O","=","6-amino-2-oxohexanoate","+","NH3","+","hydrogen","peroxide","."),4328607). assertion_content_comment('oboGo_DLysinetransaminaseactivity',s("Catalysis","of","the","reaction",":","D-lysine","+","2-oxoglutarate","=","L-glutamate","+","6-amino-2-oxohexanoate","."),4328567). assertion_content_comment('oboGo_DLysopinedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-lysopine","+","H","(","2",")","O","+","NADP","(","+",")","=","L-lysine","+","H","(","+",")","+","NADPH","+","pyruvate","."),4374741). assertion_content_comment('oboGo_DLyxoseketolIsomeraseactivity',s("Catalysis","of","the","reaction",":","D-lyxose","=","D-xylulose","."),4374783). assertion_content_comment('oboGo_DMalatedehydrogenasedecarboxylatingactivity',s("Catalysis","of","the","reaction",":","(","R",")","-malate","+","NAD","(","+",")","=","CO","(","2",")","+","NADH","+","pyruvate","."),4359065). assertion_content_comment('oboGo_DMannitoloxidaseactivity',s("Catalysis","of","the","reaction",":","mannitol","+","O2","=","mannose","+","H2O2","."),4267826). assertion_content_comment('oboGo_DMethionineExportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-methionine","(","in",")","=","ADP","+","phosphate","+","D-methionine","(","out",")"),4331493). assertion_content_comment('oboGo_DMethionineImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-methionine","(","out",")","=","ADP","+","phosphate","+","D-methionine","(","in",")"),4331473). assertion_content_comment('oboGo_DMethioninePyruvatetransaminaseactivity',s("Catalysis","of","the","reaction",":","D-methionine","+","pyruvate","=","4-methylthio-2-oxobutanoate","+","L-alanine","."),4369137). assertion_content_comment('oboGo_DMethioninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-methionine","from","one","side","of","a","membrane","to","the","other","."),4331468). assertion_content_comment('oboGo_DMethionineTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-methionine","(","out/in",")","=","ADP","+","phosphate","+","D-methionine","(","in/out",")"),4331471). assertion_content_comment('oboGo_DMethioninetransport',s("The","directed","movement","of","D-methionine","into",",","out","of",",","within",",","or","between","cells","."),4335785). assertion_content_comment('oboGo_DNA_3_MethyladenineGlycosylaseIActivity',s("Catalysis","of","the","hydrolysis","of","alkylated","DNA",";","only","recognizes","and","removes","the","alkylated","base","3-methyladenine","by","cleaving","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic","(","AP",")","site","."),4252242). assertion_content_comment('oboGo_DNA_3_MethyladenineGlycosylaseIIIActivity',s("Catalysis","of","the","hydrolysis","of","alkylated","DNA",";","recognizes","and","removes","alkylated","3-methylpurines","and","pyrimidines","by","cleaving","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic","or","apyrimidinic","(","AP",")","site","."),4325912). assertion_content_comment('oboGo_DNA_3_MethyladenineGlycosylaseIVActivity',s("Catalysis","of","the","hydrolysis","of","alkylated","DNA",";","recognizes","and","removes","both","N-3-","and","N-7-methyl","purines","by","cleaving","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic","(","AP",")","site","."),4325876). assertion_content_comment('oboGo_DNA5Adenosinemonophosphatehydrolaseactivity',s("Catalysis","of","the","reaction",":","5","'","-AMP-DNA","+","H2O","=","AMP","+","DNA",";","nucleophilic","release","of","a","covalently","linked","adenylate","residue","from","a","DNA","strand",",","leaving","a","5","'","phosphate","terminus","."),4341719). assertion_content_comment('oboGo_DNA6_4PhotolyaseActivity',s("Catalysis","of","the","reaction",":","pyrimidine-pyrimidone","(","6-4",")","photoproduct","(","in","DNA",")","=","2","pyrimidine","residues","(","in","DNA",")","Catalyzes","the","reactivation","of","ultraviolet-irradiated","DNA","."),4184327). assertion_content_comment('oboGo_DNA_7_MethylguanineGlycosylaseActivity',s("Catalysis","of","the","hydrolysis","of","alkylated","DNA",";","recognizes","and","removes","the","alkylated","base","7-methylguanine","."),4328653). assertion_content_comment('oboGo_DNAADPRibosylation',s("The","covalent","attachment","of","an","ADP-ribosyl","group","to","the","amino","group","at","N2","of","a","2","'","-deoxyguanosine","residue","in","double-stranded","DNA","."),4307815). assertion_content_comment('oboGo_DNAAlphaGlucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-glucosyl","residue","from","UDP-glucose","to","a","hydroxymethylcytosine","residue","in","DNA","."),4342965). assertion_content_comment('oboGo_DNAApurinicorapyrimidinicsitelyaseactivity',s("Catalysis","of","the","cleavage","of","the","C-O-P","bond","3","'","to","the","apurinic","or","apyrimidinic","site","in","DNA","by","a","beta-elimination","reaction",",","leaving","a","3","'","-terminal","unsaturated","sugar","and","a","product","with","a","terminal","5","'","-phosphate","."),4184040). assertion_content_comment('oboGo_DNABetaGlucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","beta-D-glucosyl","residue","from","UDP-glucose","to","a","hydroxymethylcytosine","residue","in","DNA","."),4343227). assertion_content_comment('oboGo_DNACytosine_5__MethyltransferaseActivityActingOnCpGSubstrates',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","CpG","(","in","DNA",")","=","S-adenosyl-L-homocysteine","+","5-MeCpG","(","in","DNA",")"),4280600). assertion_content_comment('oboGo_DNACytosine_5__MethyltransferaseActivityActingOnCpNpGSubstrates',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","DNA","containing","CpNpG","=","S-adenosyl-L-homocysteine","+","DNA","containing","5-MeCpNpG","."),4280848). assertion_content_comment('oboGo_DNACytosine_5__MethyltransferaseActivityActingOnCpNSubstrates',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","DNA","containing","CpN","=","S-adenosyl-L-homocysteine","+","DNA","containing","5-MeCpN","."),4280591). assertion_content_comment('oboGo_DNACytosine_5__MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","DNA","containing","cytosine","=","S-adenosyl-L-homocysteine","+","DNA","containing","5-methylcytosine","."),4190078). assertion_content_comment('oboGo_DNADeoxyinosineglycosylaseactivity',s("Catalysis","of","the","hydrolysis","of","DNA","and","polynucleotides",",","releasing","free","hypoxanthine","."),4344505). assertion_content_comment('oboGo_DNADependentatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","requires","the","presence","of","single-","or","double-stranded","DNA",",","and","it","drives","another","reaction","."),4193464). assertion_content_comment('oboGo_DNADependentdnareplicationinitiation',s("The","process","in","which","DNA","replication","is","started",";","this","involves","the","separation","of","a","stretch","of","the","DNA","double","helix",",","the","recruitment","of","DNA","polymerases","and","the","initiation","of","polymerase","action","."),4010885). assertion_content_comment('oboGo_DNADependentdnareplication',s("A","DNA","replication","process","that","uses","parental","DNA","as","a","template","for","the","DNA-dependent","DNA","polymerases","that","synthesize","the","new","strands","."),4010840). assertion_content_comment('oboGo_DNADependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","=","ADP","+","a","phosphoprotein",".","This","reaction","requires","the","presence","of","DNA","."),4202366). assertion_content_comment('oboGo_DNADependentproteinkinasecomplex',s("A","protein","complex","that","is","involved","in","the","repair","of","DNA","double-strand","breaks","and",",","in","mammals",",","V","(","D",")","J","recombination","events",".","It","consists","of","the","DNA-dependent","protein","kinase","catalytic","subunit","(","DNA-PKcs",")","and","the","DNA","end-binding","heterodimer","Ku","."),4175426). assertion_content_comment('oboGo_DNADependentproteinkinaseDnaligase4complex',s("A","large","protein","complex","which","is","involved","in","the","repair","of","DNA","double-strand","breaks","and",",","in","mammals",",","V","(","D",")","J","recombination","events",".","It","consists","of","the","DNA-dependent","protein","kinase","catalytic","subunit","(","DNA-PKcs",")",",","the","DNA","end-binding","heterodimer","Ku",",","the","nuclear","phosphoprotein","XRCC4","or","a","homolog","thereof",",","and","DNA","ligase","IV","."),4221000). assertion_content_comment('oboGo_DNADependenttranscriptionalopencomplexformation',s("Any","process","involved","in","the","melting","of","the","DNA","hybrid","of","the","core","promoter","region","within","the","transcriptional","closed","complex","of","an","RNA","polymerase","preinitiation","complex","(","PIC",")","to","produce","an","open","complex","where","the","DNA","duplex","around","the","transcription","initiation","site","is","unwound","to","form","the","transcription","bubble","."),3980450). assertion_content_comment('oboGo_DNADependenttranscriptionalpreinitiationcomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","proteins","on","promoter","DNA","to","form","the","transcriptional","preinitiation","complex","(","PIC",")",",","the","formation","of","which","is","a","prerequisite","for","transcription","."),3979187). assertion_content_comment('oboGo_DNADirecteddnapolymeraseactivity',s("Catalysis","of","the","reaction",":","deoxynucleoside","triphosphate","+","DNA","(","n",")","=","diphosphate","+","DNA","(","n","+","1",")",";","the","synthesis","of","DNA","from","deoxyribonucleotide","triphosphates","in","the","presence","of","a","DNA","template","and","primer","."),4190124). assertion_content_comment('oboGo_DNADirectedrnapolymeraseactivity',s("Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","RNA","(","n",")","=","diphosphate","+","RNA","(","n","+","1",")","Utilizes","a","DNA","template",",","i.e",".","the","catalysis","of","DNA-template-directed","extension","of","the","3","'","-end","of","an","RNA","strand","by","one","nucleotide","at","a","time",".","Can","initiate","a","chain","'","de","novo","'"),4183974). assertion_content_comment('oboGo_DNADirectedrnapolymerasecomplex',s("A","protein","complex","that","possesses","DNA-directed","RNA","polymerase","activity","."),4006720). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","RNA","(","n",")","=","diphosphate","+","RNA","(","n","+","1",")"),4184483). assertion_content_comment('oboGo_DNADirectedrnapolymeraseicomplex',s("RNA","polymerase","I",",","one","of","three","nuclear","DNA-directed","RNA","polymerases","found","in","all","eukaryotes",",","is","a","multisubunit","complex",";","typically","it","produces","rRNAs",".","Two","large","subunits","comprise","the","most","conserved","portion","including","the","catalytic","site","and","share","similarity","with","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases",".","The","remainder","of","the","complex","is","composed","of","smaller","subunits","(","generally","ten","or","more",")",",","some","of","which","are","also","found","in","RNA","polymerase","III","and","others","of","which","are","also","found","in","RNA","polymerases","II","and","III",".","Although","the","core","is","competent","to","mediate","ribonucleic","acid","synthesis",",","it","requires","additional","factors","to","select","the","appropriate","template","."),4219822). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiiactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","RNA","(","n",")","=","diphosphate","+","RNA","(","n","+","1",")"),4184003). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiicorecomplex',s("RNA","polymerase","II",",","one","of","three","nuclear","DNA-directed","RNA","polymerases","found","in","all","eukaryotes",",","is","a","multisubunit","complex",";","typically","it","produces","mRNAs",",","snoRNAs",",","and","some","of","the","snRNAs",".","Two","large","subunits","comprise","the","most","conserved","portion","including","the","catalytic","site","and","share","similarity","with","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases",".","The","largest","subunit","of","RNA","polymerase","II","contains","an","essential","carboxyl-terminal","domain","(","CTD",")","composed","of","a","variable","number","of","heptapeptide","repeats","(","YSPTSPS",")","The","remainder","of","the","complex","is","composed","of","smaller","subunits","(","generally","ten","or","more",")",",","some","of","which","are","also","found","in","RNA","polymerases","I","and","III",".","Although","the","core","is","competent","to","mediate","ribonucleic","acid","synthesis",",","it","requires","additional","factors","to","select","the","appropriate","template","."),4006726). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiiholoenzyme',s("Large","protein","complex","composed","of","the","RNA","polymerase","core","complex","and","a","variety","of","other","proteins","including","transcription","factor","complexes","TFIIA",",","D",",","E",",","F",",","and","H","which","are","required","for","promoter","recognition",",","and","the","Mediator","subcomplex",".","Catalyzes","the","synthesis","of","eukaryotic","pre-mRNA","."),3976542). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiiiactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","nucleoside","triphosphate","+","RNA","(","n",")","=","diphosphate","+","RNA","(","n","+","1",")"),4183992). assertion_content_comment('oboGo_DNADirectedrnapolymeraseiiicomplex',s("RNA","polymerase","III",",","one","of","three","nuclear","DNA-directed","RNA","polymerases","found","in","all","eukaryotes",",","is","a","multisubunit","complex",";","typically","it","produces","5S","rRNA",",","tRNAs","and","some","of","the","small","nuclear","RNAs",".","Two","large","subunits","comprise","the","most","conserved","portion","including","the","catalytic","site","and","share","similarity","with","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases",".","The","remainder","of","the","complex","is","composed","of","smaller","subunits","(","generally","ten","or","more",")",",","some","of","which","are","also","found","in","RNA","polymerase","I","and","others","of","which","are","also","found","in","RNA","polymerases","I","and","II",".","Although","the","core","is","competent","to","mediate","ribonucleic","acid","synthesis",",","it","requires","additional","factors","to","select","the","appropriate","template","."),4220161). assertion_content_comment('oboGo_DNADirectedrnapolymeraseivacomplex',s("RNA","polymerase","IVa","is","a","multisubunit","RNA","polymerase","complex","found","in","the","nucleus","of","plants","and","involved","in","accumulation","of","siRNAs","and","in","DNA","methylation-dependent","silencing","of","endogenous","repeated","sequences",".","Two","large","subunits","comprise","the","most","conserved","portion","including","the","catalytic","site","and","share","similarity","with","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases",".","The","second","largest","subunit","is","also","found","in","RNA","polymerase","IVb",",","while","the","largest","subunit","is","found","only","in","the","IVa","complex",".","The","remainder","of","the","complex","is","composed","of","smaller","subunits","."),4362587). assertion_content_comment('oboGo_DNADirectedrnapolymeraseivbcomplex',s("RNA","polymerase","IVb","is","a","multisubunit","RNA","polymerase","complex","found","in","the","nucleus","of","plants","and","involved","in","accumulation","of","siRNAs","and","in","DNA","methylation-dependent","silencing","of","endogenous","repeated","sequences",".","Two","large","subunits","comprise","the","most","conserved","portion","including","the","catalytic","site","and","share","similarity","with","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases",".","The","second","largest","subunit","is","also","found","in","RNA","polymerase","IVa",",","while","the","largest","subunit","is","found","only","in","the","IVa","complex","and","contains","an","extended","C-terminal","domain","(","CTD",")","that","includes","multiple","repeats","of","a","16","amino-acid","consensus","sequence","as","well","as","other","sequences",".","The","remainder","of","the","complex","is","composed","of","smaller","subunits","."),4362538). assertion_content_comment('oboGo_DNADirectedrnapolymeraseivcomplex',s("RNA","polymerase","IV","is","a","multisubunit","RNA","polymerase","complex","found","in","the","nucleus","of","plants",".","In","addition","to","RNA","polymerases","I",",","II",",","and","III",",","the","essential","RNA","polymerases","present","in","all","eukaryotes",",","plants","have","two","additional","nuclear","RNA","polymerases",",","Pol","IV","and","Pol","V",",","that","play","nonredundant","roles","in","siRNA-directed","DNA","methylation","and","gene","silencing",".","Pol","IV","is","required","for","siRNA","production","and","Pol","V","is","required","for","generating","noncoding","transcripts","at","target","loci",".","Pol","IV","is","composed","of","subunits","that","are","paralogous","or","identical","to","the","12","subunits","of","Pol","II",".","The","largest","and","second-largest","subunits","of","Pol","IV","are","the","catalytic","subunits","and","share","similarity","with","the","corresponding","subunits","of","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases","."),4362529). assertion_content_comment('oboGo_DNADirectedrnapolymerasevcomplex',s("RNA","polymerase","V","is","a","multisubunit","RNA","polymerase","complex","found","in","the","nucleus","of","plants",".","In","addition","to","RNA","polymerases","I",",","II",",","and","III",",","the","essential","RNA","polymerases","present","in","all","eukaryotes",",","plants","have","two","additional","nuclear","RNA","polymerases",",","Pol","IV","and","Pol","V",",","that","play","nonredundant","roles","in","siRNA-directed","DNA","methylation","and","gene","silencing",".","Pol","IV","is","required","for","siRNA","production","and","Pol","V","is","required","for","generating","noncoding","transcripts","at","target","loci",".","Pol","V","is","composed","of","subunits","that","are","paralogous","or","identical","to","the","12","subunits","of","Pol","II",".","The","largest","and","second-largest","subunits","of","Pol","V","are","the","catalytic","subunits","and","share","similarity","with","the","corresponding","subunits","of","other","eukaryotic","and","bacterial","multisubunit","RNA","polymerases","."),4180961). assertion_content_comment('oboGo_DNADoubleStrandbreakprocessinginvolvedinrepairviasingleStrandannealing',s("The","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","that","results","in","the","repair","of","a","double","strand","break","via","single-strand","annealing","."),4025492). assertion_content_comment('oboGo_DNADoubleStrandbreakprocessinginvolvedinrepairviasynthesisDependentstrandannealing',s("The","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","that","results","in","the","repair","of","a","double","strand","break","via","synthesis-dependent","strand","annealing","."),4025502). assertion_content_comment('oboGo_DNADoubleStrandbreakprocessing',s("The","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","."),3977184). assertion_content_comment('oboGo_DNALigaseIIIXrcc1complex',s("A","protein","complex","that","contains","DNA","ligase","III","and","XRCC1",",","and","is","involved","in","base","excision","repair","."),4175531). assertion_content_comment('oboGo_DNALigationInvolvedInDNADependentdnareplication',s("The","re-formation","of","a","broken","phosphodiester","bond","in","the","DNA","backbone",",","carried","out","by","DNA","ligase",",","that","contributes","to","DNA-dependent","DNA","replication","."),4119505). assertion_content_comment('oboGo_DNAMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","to","a","DNA","molecule","."),4190067). assertion_content_comment('oboGo_DNAN1Methyladeninedioxygenaseactivity',s("Catalysis","of","the","oxidative","demethylation","of","N1-methyladenine","and","N3-methylcytosine","in","DNA","and","RNA",",","with","concomitant","decarboxylation","of","2-oxoglutarate","and","releases","oxidized","methylgroup","on","N1-methyladenine","and","N3-methylcytosine","as","formaldehyde","."),4325938). assertion_content_comment('oboGo_DNANGlycosylaseactivity',s("Catalysis","of","the","removal","of","damaged","bases","by","cleaving","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic/apyrimidinic","(","AP",")","site","."),4184075). assertion_content_comment('oboGo_DNARecombinaseAssemblyInvolvedInGeneConversionAtMatingTypelocus',s("The","aggregation",",","arrangement","and","bonding","together","of","strand","exchange","proteins","(","recombinases",")","into","higher","order","oligomers","on","single-stranded","DNA",",","involved","in","the","conversion","of","the","mating-type","locus","from","one","allele","to","another","."),4074268). assertion_content_comment('oboGo_DNAReplicationDependentnucleosomeassembly',s("The","formation","of","nucleosomes","on","newly","replicated","DNA",",","coupled","to","strand","elongation","."),4222461). assertion_content_comment('oboGo_DNAReplicationDependentnucleosomedisassembly',s("The","controlled","breakdown","of","nucleosomes","on","newly","replicated","DNA",",","coupled","to","strand","elongation","."),4349224). assertion_content_comment('oboGo_DNAReplicationDependentnucleosomeorganization',s("The","formation","or","destruction","of","chromatin","structures","on","newly","replicated","DNA",",","coupled","to","strand","elongation","."),4222458). assertion_content_comment('oboGo_DNAReplicationIndependentnucleosomeassembly',s("The","formation","of","nucleosomes","outside","the","context","of","DNA","replication","."),4222439). assertion_content_comment('oboGo_DNAReplicationIndependentnucleosomedisassembly',s("The","controlled","breakdown","of","nucleosomes","outside","the","context","of","DNA","replication","."),4349234). assertion_content_comment('oboGo_DNAReplicationIndependentnucleosomeorganization',s("The","formation","or","destruction","of","chromatin","structures",",","occurring","outside","the","context","of","DNA","replication","."),4222436). assertion_content_comment('oboGo_DNARestrictionModificationsystem',s("Any","process","that","protect","an","organism","from","invading","foreign","DNA","by","methylation","of","self","DNA","at","specific","sequences","and","nucleolytic","cleavage","of","unmethylated","foreign","DNA","."),4259537). assertion_content_comment('oboGo_DNAStrandRenaturationInvolvedInDoubleStrandbreakrepair',s("The","identification","and","annealing","of","complementary","base","pairs","in","single-strand","DNA","that","contributes","to","double-strand","break","repair","."),4134850). assertion_content_comment('oboGo_DNASynthesisInvolvedInDoubleStrandbreakrepairviahomologousrecombination',s("The","synthesis","of","DNA","that","contributes","to","the","process","of","double-strand","break","repair","via","homologous","recombination","."),4092935). assertion_content_comment('oboGo_DNASynthesisInvolvedInDoubleStrandbreakrepairviasingleStrandannealing',s("The","synthesis","of","DNA","that","contributes","to","the","process","of","double-strand","break","repair","via","single-strand","annealing","."),4092902). assertion_content_comment('oboGo_DNATopoisomeraseATPHydrolyzingactivatoractivity',s("Increases","the","activity","of","ATP-hydrolyzing","DNA","topoisomerase",".","DNA","topoisomerase","(","ATP-hydrolyzing",")","regulator","activity","catalyzes","a","DNA","topological","transformation","by","transiently","cleaving","a","pair","of","complementary","DNA","strands","to","form","a","gate","through","which","a","second","double-stranded","DNA","segment","is","passed",",","after","which","the","severed","strands","in","the","first","DNA","segment","are","rejoined",";","product","release","is","coupled","to","ATP","binding","and","hydrolysis",";","changes","the","linking","number","in","multiples","of","2","."),4157538). assertion_content_comment('oboGo_DNATopoisomeraseATPHydrolyzingactivity',s("Catalysis","of","a","DNA","topological","transformation","by","transiently","cleaving","a","pair","of","complementary","DNA","strands","to","form","a","gate","through","which","a","second","double-stranded","DNA","segment","is","passed",",","after","which","the","severed","strands","in","the","first","DNA","segment","are","rejoined",";","product","release","is","coupled","to","ATP","binding","and","hydrolysis",";","changes","the","linking","number","in","multiples","of","2","."),4184407). assertion_content_comment('oboGo_DNATopoisomeraseATPHydrolyzinginhibitoractivity',s("Stops",",","prevents","or","reduces","the","activity","of","ATP-hydrolyzing","DNA","topoisomerase",".","ATP-hydrolyzing","DNA","topoisomerase","catalyzes","the","DNA","topological","transformation","by","transiently","cleaving","a","pair","of","complementary","DNA","strands","to","form","a","gate","through","which","a","second","double-stranded","DNA","segment","is","passed",",","after","which","the","severed","strands","in","the","first","DNA","segment","are","rejoined",";","product","release","is","coupled","to","ATP","binding","and","hydrolysis",";","changes","the","linking","number","in","multiples","of","2","."),4253225). assertion_content_comment('oboGo_DNATopoisomeraseATPHydrolyzingregulatoractivity',s("Modulates","the","activity","of","ATP-hydrolyzing","DNA","topoisomerase",".","DNA","topoisomerase","(","ATP-hydrolyzing",")","regulator","activity","catalyzes","a","DNA","topological","transformation","by","transiently","cleaving","a","pair","of","complementary","DNA","strands","to","form","a","gate","through","which","a","second","double-stranded","DNA","segment","is","passed",",","after","which","the","severed","strands","in","the","first","DNA","segment","are","rejoined",";","product","release","is","coupled","to","ATP","binding","and","hydrolysis",";","changes","the","linking","number","in","multiples","of","2","."),4157536). assertion_content_comment('oboGo_DNATopoisomeraseComplexATPHydrolyzing',s("Complex","that","possesses","DNA","topoisomerase","(","ATP-hydrolyzing",")","activity","."),4259759). assertion_content_comment('oboGo_DNopalinedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N2-","(","D-1",",","3-dicarboxypropyl",")","-L-arginine","+","NADP","+","+","H2O","=","L-arginine","+","2-oxoglutarate","+","NADPH","."),4374768). assertion_content_comment('oboGo_DOctopinedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N2-","(","D-1-carboxyethyl",")","-L-arginine","+","NAD","+","+","H2O","=","L-arginine","+","pyruvate","+","NADH","."),4374612). assertion_content_comment('oboGo_DodecanoylAcylCarrierProteinhydrolaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","dodecanoyl-","[","acyl-carrier","protein","]","=","dodecanoate","+","[","acyl-carrier","protein","]"),4368604). assertion_content_comment('oboGo_DodecenoylCoadeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","3-cis-dodecenoyl-CoA","=","2-trans-dodecenoyl-CoA","."),4210690). assertion_content_comment('oboGo_DolicholLinkedoligosaccharidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","dolichol-linked","oligosaccharide",",","usually","by","a","stepwise","addition","of","glycosyl","chains","to","endoplasmic","reticulum","membrane-bound","dolichol-P","."),4009834). assertion_content_comment('oboGo_DolicholOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","palmitoyl-CoA","+","dolichol","=","CoA","+","dolichyl","palmitate","."),4376170). assertion_content_comment('oboGo_DolicholPhosphateMannosesynthasecomplex',s("A","protein","complex","that","possesses","dolichyl-phosphate","beta-D-mannosyltransferase","activity",";","contains","a","catalytic","subunit",",","a","regulatory","subunit",",","and","a","third","subunit","that","stabilizes","the","complex",".","In","human","and","several","other","metazoa",",","the","subunits","are","named","DPM1",",","DPM2","and","DPM3",",","respectively","."),4347700). assertion_content_comment('oboGo_DolichylDiphosphatePolyphosphatephosphotransferaseactivity',s("Catalysis","of","the","reaction",":","dolichyl","diphosphate","+","long-chain-polyphosphate","=","dolichol-phosphate","+","long-chain-polyphosphate","."),4368388). assertion_content_comment('oboGo_DolichylDiphosphooligosaccharideProteinglycotransferaseactivity',s("Catalysis","of","the","reaction",":","dolichyl","diphosphooligosaccharide","+","protein","L-asparagine","=","dolichyl","diphosphate","+","a","glycoprotein","with","the","oligosaccharide","chain","attached","by","glycosylamine","linkage","to","protein","L-asparagine","."),4204287). assertion_content_comment('oboGo_DolichylPhosphataseactivity',s("Catalysis","of","the","reaction",":","dolichyl","phosphate","+","H2O","=","dolichol","+","phosphate","."),4376139). assertion_content_comment('oboGo_DolichylPhosphatealphaNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","dolichyl","phosphate","=","UDP","+","dolichyl","N-acetyl-alpha-D-glucosaminyl","phosphate","."),4210672). assertion_content_comment('oboGo_DolichylPhosphatebetaDMannosyltransferaseactivity',s("Catalysis","of","the","reaction",":","GDP-mannose","+","dolichyl","phosphate","=","GDP","+","dolichyl","D-mannosyl","phosphate","."),4204171). assertion_content_comment('oboGo_DolichylPhosphatebetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","dolichyl","phosphate","=","UDP","+","dolichyl","beta-D-glucosyl","phosphate","."),4204090). assertion_content_comment('oboGo_DolichylPhosphatedXylosyltransferaseactivity',s("Catalysis","of","the","reaction",":","dolichol-phosphate","+","UDP-D-xylose","=","dolichyl","D-xylosyl","phosphate","+","UDP","."),4367390). assertion_content_comment('oboGo_DolichylPhosphateGlucoseGlycolipidalphaGlucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-glucosyl","residue","from","dolichyl-phosphate","D-glucose","into","a","membrane","lipid-linked","oligosaccharide","."),4204161). assertion_content_comment('oboGo_DolichylphosphateGlucosephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","dolichyl","beta-D-glucosyl","phosphate","+","H2O","=","dolichol-phosphate","+","beta-D-glucose","."),4368453). assertion_content_comment('oboGo_DolichylPhosphateMannoseGlycolipidalphaMannosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-mannosyl","residue","from","dolichyl-phosphate","D-mannose","into","membrane","lipid-linked","oligosaccharide","."),4204149). assertion_content_comment('oboGo_DolichylphosphateMannosephosphodiesteraseactivity',s("Catalysis","of","the","reaction",":","dolichyl","beta-D-mannosyl","phosphate","+","H2O","=","dolichol-phosphate","+","mannose","."),4368410). assertion_content_comment('oboGo_DolichylPhosphateMannoseProteinmannosyltransferaseactivity',s("Catalysis","of","the","reaction",":","dolichyl","phosphate","D-mannose","+","protein","=","dolichyl","phosphate","+","O-D-mannosylprotein","."),4210613). assertion_content_comment('oboGo_DolichylPhosphateMannoseProteinmannosyltransferasecomplex',s("A","complex","that","possesses","dolichyl-phosphate-mannose-protein","mannosyltransferase","activity",";","usually","includes","members","of","the","PMT1","and","PMT2","protein","subfamilies","."),4060787). assertion_content_comment('oboGo_DolichylPyrophosphateGlc1Man9GlcNAc2Alpha_13_GlucosyltransferaseActivity',s("Catalysis","of","the","addition","of","the","second","glucose","residue","to","the","lipid-linked","oligosaccharide","precursor","for","N-linked","glycosylation",";","the","transfer","of","glucose","from","dolichyl","phosphate","glucose","(","Dol-P-Glc",")","on","to","the","lipid-linked","oligosaccharide","Glc","(","1",")","Man","(","9",")","GlcNAc","(","2",")","-PP-Dol","."),4314166). assertion_content_comment('oboGo_DolichylPyrophosphateMan7GlcNAc2Alpha_13_GlucosyltransferaseActivity',s("Catalysis","of","the","addition","of","a","glucose","residue","to","the","lipid-linked","oligosaccharide","precursor","for","N-linked","glycosylation",";","the","transfer","of","glucose","from","dolichyl","phosphate","glucose","(","Dol-P-Glc",")","on","to","the","lipid-linked","oligosaccharide","Man","(","7",")","GlcNAc","(","2",")","-PP-Dol","."),4341027). assertion_content_comment('oboGo_DolichylPyrophosphateMan9GlcNAc2Alpha_13_GlucosyltransferaseActivity',s("Catalysis","of","the","addition","of","the","first","glucose","residue","to","the","lipid-linked","oligosaccharide","precursor","for","N-linked","glycosylation",";","the","transfer","of","glucose","from","dolichyl","phosphate","glucose","(","Dol-P-Glc",")","on","to","the","lipid-linked","oligosaccharide","Man","(","9",")","GlcNAc","(","2",")","-PP-Dol","."),4314194). assertion_content_comment('oboGo_DolichylXylosylPhosphateProteinxylosyltransferaseactivity',s("Catalysis","of","the","reaction",":","dolichyl","D-xylosyl","phosphate","+","protein","=","dolichol-phosphate","+","D-xylosylprotein","."),4367300). assertion_content_comment('oboGo_DopamineBetaMonooxygenaseactivity',s("Catalysis","of","the","reaction",":","L-ascorbate","+","dopamine","+","O","(","2",")","=","(","R",")","-noradrenaline","+","dehydroascorbate","+","H","(","2",")","O","."),4205335). assertion_content_comment('oboGo_DOrnithine45Aminomutaseactivity',s("Catalysis","of","the","reaction",":","D-ornithine","=","(","2R",",","4S",")","-2",",","4-diaminopentanoate","."),4374637). assertion_content_comment('oboGo_DOrnithinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-ornithine",",","the","D-enantiomer","of","the","amino","acid","ornithine",",","i.e",".","(","2R",")","-2",",","5-diaminopentanoic","acid","."),4347237). assertion_content_comment('oboGo_DoubleStrandbreakrepair',s("The","repair","of","double-strand","breaks","in","DNA","via","homologous","and","nonhomologous","mechanisms","to","reform","a","continuous","DNA","helix","."),3977182). assertion_content_comment('oboGo_DoubleStrandbreakrepairviabreakInducedreplication',s("The","error-free","repair","of","a","double-strand","break","in","DNA","in","which","the","centromere-proximal","end","of","a","broken","chromosome","searches","for","a","homologous","region","in","an","intact","chromosome",".","DNA","synthesis","initiates","from","the","3","'","end","of","the","invading","DNA","strand",",","using","the","intact","chromosome","as","the","template",",","and","progresses","to","the","end","of","the","chromosome","."),4363797). assertion_content_comment('oboGo_DoubleStrandbreakrepairviahomologousrecombination',s("The","error-free","repair","of","a","double-strand","break","in","DNA","in","which","the","broken","DNA","molecule","is","repaired","using","homologous","sequences",".","A","strand","in","the","broken","DNA","searches","for","a","homologous","region","in","an","intact","chromosome","to","serve","as","the","template","for","DNA","synthesis",".","The","restoration","of","two","intact","DNA","molecules","results","in","the","exchange",",","reciprocal","or","nonreciprocal",",","of","genetic","material","between","the","intact","DNA","molecule","and","the","broken","DNA","molecule","."),3977256). assertion_content_comment('oboGo_DoubleStrandbreakrepairvianonhomologousendjoining',s("The","repair","of","a","double-strand","break","in","DNA","in","which","the","two","broken","ends","are","rejoined","with","little","or","no","sequence","complementarity",".","Information","at","the","DNA","ends","may","be","lost","due","to","the","modification","of","broken","DNA","ends","."),4222393). assertion_content_comment('oboGo_DoubleStrandbreakrepairviasingleStrandannealingremovalofnonhomologousends',s("During","DSBR","via","single-strand","annealing",",","the","removal","of","nonhomologous","sequences","at","the","broken","3","'","single-strand","DNA","end","before","DNA","repair","synthesis","can","occur","."),3978068). assertion_content_comment('oboGo_DoubleStrandbreakrepairviasingleStrandannealing',s("Repair","of","a","DSB","made","between","two","repeated","sequences","oriented","in","the","same","direction","occurs","primarily","by","the","single","strand","annealing","pathway",".","The","ends","of","the","break","are","processed","by","a","5","'","to","3","'","exonuclease",",","exposing","complementary","single-strand","regions","of","the","direct","repeats","that","can","anneal",",","resulting","in","a","deletion","of","the","unique","DNA","between","the","direct","repeats","."),3977979). assertion_content_comment('oboGo_DoubleStrandbreakrepairviasynthesisDependentstrandannealing',s("SDSA","is","a","major","mechanism","of","double-strand","break","repair","in","mitosis","which","allows","for","the","error-free","repair","of","a","double-strand","break","without","the","exchange","of","adjacent","sequences",".","The","broken","DNA","searches","for","and","base","pairs","with","a","homologous","region","in","an","intact","chromosome",".","DNA","synthesis","initiates","from","the","3","'","end","of","the","invading","DNA","strand",",","using","the","intact","chromosome","as","the","template",".","Newly","synthesized","DNA","is","then","displaced","from","the","template","and","anneal","with","its","complement","on","the","other","side","of","the","double-strand","break","."),3977264). assertion_content_comment('oboGo_DoubleStrandeddnabinding',s("Interacting","selectively","and","non-covalently","with","double-stranded","DNA","."),4193308). assertion_content_comment('oboGo_DoubleStrandeddnaDependentatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","this","reaction","requires","the","presence","of","double-stranded","DNA",",","and","it","drives","another","reaction","."),4341301). assertion_content_comment('oboGo_Double_StrandedDNASpecific3_5ExodeoxyribonucleaseActivity',s("Catalysis","of","the","sequential","cleavage","of","mononucleotides","from","a","free","3","'","terminus","of","a","double-stranded","DNA","molecule","."),4255462). assertion_content_comment('oboGo_Double_StrandedDNASpecific5_3ExodeoxyribonucleaseActivity',s("Catalysis","of","the","sequential","cleavage","of","mononucleotides","from","a","free","5","'","terminus","of","a","double-stranded","DNA","molecule","."),4183339). assertion_content_comment('oboGo_DoubleStrandeddnaspecificexodeoxyribonucleaseactivity',s("Catalysis","of","the","sequential","cleavage","of","mononucleotides","from","a","free","5","'","or","3","'","terminus","of","a","double-stranded","DNA","molecule","."),4183316). assertion_content_comment('oboGo_DoubleStrandedmethylateddnabinding',s("Interacting","selectively","and","non-covalently","with","double-stranded","methylated","DNA",".","Cytosine","methylation","in","DNA","is","an","important","mechanism","for","establishing","stable","heritable","epigenetic","marks","."),4332251). assertion_content_comment('oboGo_DoubleStrandedrnaadenosinedeaminaseactivity',s("Catalysis","of","the","reaction",":","adenosine","+","H2O","=","inosine","+","NH3",",","in","a","double-stranded","RNA","molecule","."),4192556). assertion_content_comment('oboGo_DoubleStrandedrnabinding',s("Interacting","selectively","and","non-covalently","with","double-stranded","RNA","."),4192531). assertion_content_comment('oboGo_DoubleStrandedrnaSpecificribonucleaseactivity',s("Catalysis","of","the","hydrolysis","of","phosphodiester","bonds","in","double-stranded","RNA","molecules","."),4329912). assertion_content_comment('oboGo_DoubleStrandedtelomericdnabinding',s("Interacting","selectively","and","non-covalently","with","double-stranded","telomere-associated","DNA","."),4193361). assertion_content_comment('oboGo_DoubleStrandsingleStranddnajunctionbinding',s("Interacting","selectively","and","non-covalently","with","a","region","of","DNA","that","contains","double-stranded","DNA","flanked","by","a","region","of","single-stranded","DNA","."),4362821). assertion_content_comment('oboGo_DPinitoldehydrogenaseactivity',s("Catalysis","of","the","reaction",":","5D-5-O-methyl-chiro-inositol","+","NADP","(","+",")","=","2D-5-O-methyl-2",",","3",",","5/4",",","6-pentahydroxycyclohexanone","+","H","(","+",")","+","NADPH","."),4374658). assertion_content_comment('oboGo_DProlinereductasedithiolactivity',s("Catalysis","of","the","reaction",":","lipoate","+","5-aminopentanoate","=","dihydrolipoate","+","D-proline","."),4270420). assertion_content_comment('oboGo_D_Ribitol_5_PhosphateCytidylyltransferaseActivity',s("Catalysis","of","the","reaction",":","D-ribitol","5-phosphate","+","CTP","=","CDP-ribitol","+","diphosphate","."),4368232). assertion_content_comment('oboGo_DRibosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-ribose",",","(","ribo-pentose",")"),4225268). assertion_content_comment('oboGo_DRibosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-ribose","(","ribo-pentose",")"),4239176). assertion_content_comment('oboGo_DRiboseImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-ribose","(","out",")","=","ADP","+","phosphate","+","D-ribose","(","in",")"),4289564). assertion_content_comment('oboGo_DRibosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-ribose","(","ribo-pentose",")","As","beta-D-ribofuranose",",","D-ribose","forms","the","glycose","group","of","all","ribonucleosides",",","ribonucleotides","and","ribonucleic","acids",",","and","also","of","ribose","phosphates",",","various","glycosides",",","some","coenzymes","and","some","forms","of","vitamin","B12","."),4225240). assertion_content_comment('oboGo_DRibosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-ribose","from","one","side","of","the","membrane","to","the","other",".","As","beta-D-ribofuranose",",","D-ribose","forms","the","glycose","group","of","all","ribonucleosides",",","ribonucleotides","and","ribonucleic","acids",",","and","also","of","ribose","phosphates",",","various","glycosides",",","some","coenzymes","and","some","forms","of","vitamin","B12","."),4289561). assertion_content_comment('oboGo_DRibosetransport',s("The","directed","movement","of","D-ribose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","As","beta-D-ribofuranose",",","D-ribose","forms","the","glycose","group","of","all","ribonucleosides",",","ribonucleotides","and","ribonucleic","acids",",","and","also","of","ribose","phosphates",",","various","glycosides",",","some","coenzymes","and","some","forms","of","vitamin","B12","."),4291052). assertion_content_comment('oboGo_DRibulokinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","D-ribulose","=","ADP","+","D-ribulose","5-phosphate","."),4237532). assertion_content_comment('oboGo_DSedoheptulose7Phosphateisomeraseactivity',s("Catalysis","of","the","reaction",":","D-sedoheptulose-7-phosphate","=","D-alpha",",","beta-D-heptose","7-phosphate","."),4247855). assertion_content_comment('oboGo_DSerineammoniaLyaseactivity',s("Catalysis","of","the","reaction",":","D-serine","=","pyruvate","+","NH3","."),4252210). assertion_content_comment('oboGo_DSerinebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-serine",",","the","D-enantiomer","of","serine",",","i.e",".","(","2R",")","-2-amino-3-hydroxypropanoic","acid",".","D-serine","is","often","formed","by","racemization","of","L-serine","."),4179180). assertion_content_comment('oboGo_DSerinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-serine",",","the","D-enantiomer","of","serine",",","i.e",".","(","2R",")","-2-amino-3-hydroxypropanoic","acid","."),4179177). assertion_content_comment('oboGo_DSerinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-serine","from","one","side","of","a","membrane","to","the","other",".","D-serine","is","the","D-enantiomer","of","2-amino-3-hydroxypropanoic","acid","."),4315654). assertion_content_comment('oboGo_DSerinetransport',s("The","directed","movement","of","D-serine",",","the","D-enantiomer","of","2-amino-3-hydroxypropanoic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4315609). assertion_content_comment('oboGo_DSorbitoldehydrogenaseacceptoractivity',s("Catalysis","of","the","reaction",":","D-sorbitol","+","acceptor","=","L-sorbose","+","reduced","acceptor","."),4374679). assertion_content_comment('oboGo_DTartratedehydrataseactivity',s("Catalysis","of","the","reaction",":","D-tartrate","=","H","(","2",")","O","+","oxaloacetate","."),4375083). assertion_content_comment('oboGo_DTDP_4_Amino_46_Dideoxy_D_GlucoseTransaminaseActivity',s("Catalysis","of","the","reaction",":","dTDP-4-amino-4",",","6-dideoxy-D-glucose","+","2-oxoglutarate","=","dTDP-4-dehydro-6-deoxy-D-glucose","+","L-glutamate","."),4237813). assertion_content_comment('oboGo_DTDP_4_Amino_46_DideoxygalactoseTransaminaseActivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","dTDP-4-amino-4",",","6-dideoxy-D-galactose","=","L-glutamate","+","dTDP-4-dehydro-6-deoxy-D-galactose","."),4237839). assertion_content_comment('oboGo_DTDP_4_Dehydro_6_DeoxyglucoseReductaseActivity',s("Catalysis","of","the","reaction",":","dTDP-D-fucose","+","NADP","(","+",")","=","dTDP-4-dehydro-6-deoxy-alpha-D-glucose","+","H","(","+",")","+","NADPH","."),4268558). assertion_content_comment('oboGo_DTDP_4_Dehydrorhamnose35_EpimeraseActivity',s("Catalysis","of","the","reaction",":","dTDP-4-dehydro-6-deoxy-alpha-D-glucose","=","dTDP-4-dehydro-6-deoxy-L-mannose","."),4250458). assertion_content_comment('oboGo_DTDP_4_DehydrorhamnoseReductaseActivity',s("Catalysis","of","the","reaction",":","dTDP-6-deoxy-L-mannose","+","NADP","(","+",")","=","dTDP-4-dehydro-6-deoxy-L-mannose","+","H","(","+",")","+","NADPH","."),4250441). assertion_content_comment('oboGo_DTDP_6_Deoxy_L_Talose4_DehydrogenaseActivity',s("Catalysis","of","the","reaction",":","dTDP-6-deoxy-L-talose","+","NADP","(","+",")","=","dTDP-4-dehydro-6-deoxy-L-mannose","+","H","(","+",")","+","NADPH","."),4364471). assertion_content_comment('oboGo_DTDP_Dihydrostreptose_Streptidine_6_PhosphateDihydrostreptosyltransferaseActivity',s("Catalysis","of","the","reaction",":","dTDP-L-dihydrostreptose","+","streptidine","6-phosphate","=","O-","(","1-","&","gt",";","4",")","-alpha-L-dihydrostreptosyl-streptidine","6-phosphate","+","dTDP","+","H","(","+",")"),4367378). assertion_content_comment('oboGo_DTDPGalactose6Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","dTDP-D-galactose","+","2","NADP","+","+","H2O","=","dTDP-D-galacturonate","+","2","NADPH","+","2","H","+"),4341822). assertion_content_comment('oboGo_DTDPGlucose46Dehydrataseactivity',s("Catalysis","of","the","reaction",":","dTDP-glucose","=","dTDP-4-dehydro-6-deoxy-alpha-D-glucose","+","H","(","2",")","O","."),4254155). assertion_content_comment('oboGo_DTDPMannosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","dTDP-mannose",",","a","substance","composed","of","mannose","in","glycosidic","linkage","with","deoxyribosylthymine","diphosphate","."),4239095). assertion_content_comment('oboGo_DTDPMannosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","dTDP-mannose",",","a","substance","composed","of","mannose","in","glycosidic","linkage","with","deoxyribosylthymine","diphosphate","."),4239092). assertion_content_comment('oboGo_DTDPRhamnosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","dTDP-rhamnose",",","a","substance","composed","of","rhamnose","in","glycosidic","linkage","with","deoxyribosylthymine","diphosphate","."),4239147). assertion_content_comment('oboGo_DTDPRhamnosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","dTDP-rhamnose",",","a","substance","composed","of","rhamnose","in","glycosidic","linkage","with","deoxyribosylthymine","diphosphate","."),4239144). assertion_content_comment('oboGo_DThreoAldose1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","a","D-threo-aldose","+","NAD","+","=","a","D-threo-aldono-1",",","5-lactone","+","NADH","."),4374705). assertion_content_comment('oboGo_DThreoninealdolaseactivity',s("Catalysis","of","the","reaction",":","D-threonine","(","or","D-allo-threonine",")","=","glycine","+","acetaldehyde","."),4326794). assertion_content_comment('oboGo_DTryptophannAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-tryptophan","+","acetyl-CoA","=","N-acetyl-D-tryptophan","+","CoA","+","H","(","+",")"),4374977). assertion_content_comment('oboGo_DTryptophannMalonyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-tryptophan","+","malonyl-CoA","=","N","(","2",")","-malonyl-D-tryptophan","+","CoA","+","H","(","+",")"),4374967). assertion_content_comment('oboGo_DTyrosylTrnatyrdeacylaseactivity',s("Catalysis","of","the","reaction",":","D-tyrosyl-tRNA","(","Tyr",")","=","D-tyrosine","+","tRNA","(","Tyr",")","Hydrolysis","of","the","removal","of","D-tyrosine","from","tyrosine","resides","in","charged","tRNA","."),4283366). assertion_content_comment('oboGo_DXylose1Dehydrogenasenadactivity',s("Catalysis","of","the","reaction",":","D-xylose","+","NAD","+","=","D-xylonolactone","+","NADH","."),4374938). assertion_content_comment('oboGo_DXylose1Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","D-xylose","+","NADP","(","+",")","=","D-xylono-1",",","5-lactone","+","H","(","+",")","+","NADPH","."),4374954). assertion_content_comment('oboGo_DXylosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","D-xylose",",","a","naturally","occurring","plant","polysaccharide","."),4315166). assertion_content_comment('oboGo_DXylosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","D-xylose",",","a","naturally","occurring","plant","polysaccharide","."),4095963). assertion_content_comment('oboGo_DXylose_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","D-xylose","(","out",")","+","H","+","(","out",")","=","D-xylose","(","in",")","+","H","+","(","in",")"),4292817). assertion_content_comment('oboGo_DXyloseImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","D-xylose","(","out",")","=","ADP","+","phosphate","+","D-xylose","(","in",")"),4289629). assertion_content_comment('oboGo_DXylosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","D-xylose",",","a","naturally","occurring","plant","polysaccharide","."),4095960). assertion_content_comment('oboGo_DXylose_Nadpreductaseactivity',s("Catalysis","of","the","reaction",":","D-xylitol","+","NADP","+","=","D-xylose","+","NADPH","+","H","+"),4337337). assertion_content_comment('oboGo_DXylosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","D-xylose","from","one","side","of","the","membrane","to","the","other",".","D-xylose","(","the","naturally","occurring","enantiomer","is","always","D-",")","is","a","constituent","of","plant","polysaccharides","."),4289625). assertion_content_comment('oboGo_DXylosetransport',s("The","directed","movement","of","D-xylose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","D-xylose","(","the","naturally","occurring","enantiomer","is","always","D-",")","is","a","constituent","of","plant","polysaccharides","."),4291062). assertion_content_comment('oboGo_DXylulosereductaseactivity',s("Catalysis","of","the","reaction",":","NAD","(","+",")","+","xylitol","=","D-xylulose","+","H","(","+",")","+","NADH","."),4359219). assertion_content_comment('oboGo_DyneinDrivenmeioticoscillatorynuclearmovement',s("The","cell","cycle","process","in","which","oscillatory","movement","of","the","nucleus","during","meiotic","prophase","I","occurs",".","This","oscillatory","movement","is","led","by","an","astral","microtubule","array","emanating","from","the","spindle","pole","body",",","and","driven","by","the","microtubule","motor","cytoplasmic","dynein",".","It","is","known","to","play","a","central","role","in","meiotic","recombination","and","homologous","chromosome","pairing",";","as","observed","in","S",".","pombe","."),4061232). assertion_content_comment('oboGo_DystrophinAssociatedglycoproteincomplex',s("A","multiprotein","complex","that","forms","a","strong","mechanical","link","between","the","cytoskeleton","and","extracellular","matrix",";","typical","of",",","but","not","confined","to",",","muscle","cells",".","The","complex","is","composed","of","transmembrane",",","cytoplasmic",",","and","extracellular","proteins",",","including","dystrophin",",","sarcoglycans",",","dystroglycan",",","dystrobrevins",",","syntrophins",",","sarcospan",",","caveolin-3",",","and","NO","synthase","."),4033818). assertion_content_comment('oboGo_EBetaCaryophyllenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","-",")","-E-beta-caryophyllene","+","diphosphate","."),4182193). assertion_content_comment('oboGo_EBetaOcimenesynthaseactivity',s("Catalysis","of","the","reaction",":","geranyl","diphosphate","=","(","E",")","-beta-ocimene","+","diphosphate","."),4349324). assertion_content_comment('oboGo_EBoxbinding',s("Interacting","selectively","and","non-covalently","with","an","E-box",",","a","DNA","motif","with","the","consensus","sequence","CANNTG","that","is","found","in","the","promoters","of","a","wide","array","of","genes","expressed","in","neurons",",","muscle","and","other","tissues","."),4178412). assertion_content_comment('oboGo_EcdysisChitinBasedcuticle',s("The","shedding","of","the","old","chitin-based","cuticlar","fragments","during","the","molting","cycle",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4045279). assertion_content_comment('oboGo_EcdysisCollagenAndCuticulinBasedcuticle',s("The","shedding","of","the","old","collagen","and","cuticulin-based","cuticle","fragments","during","the","molting","cycle",".","Examples","of","this","process","are","found","in","invertebrates","."),4078460). assertion_content_comment('oboGo_EcdysisProteinBasedcuticle',s("The","shedding","of","the","old","protein-based","cuticular","fragments","during","the","molting","cycle",".","Examples","of","this","process","are","found","in","invertebrates","."),4045276). assertion_content_comment('oboGo_EcdysisTriggeringhormoneactivity',s("The","action","characteristic","of","ecdysis-triggering","hormone",",","a","peptide","hormone","that",",","upon","receptor","binding",",","initiates","pre-ecdysis","and","ecdysis","(","i.e",".","cuticle","shedding",")","through","direct","action","on","the","central","nervous","system","."),4256047). assertion_content_comment('oboGo_EcdysisTriggeringhormonereceptoractivity',s("Combining","with","ecdysis-triggering","hormone","to","initiate","a","change","in","cell","activity","."),4316598). assertion_content_comment('oboGo_Ecdysone20Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","Ecdysone","+","O","(","2",")","=","20-hydroxyecdysone","+","A","+","H","(","2",")","O","."),4205310). assertion_content_comment('oboGo_EcdysoneMediatedinductionofsalivaryglandcellautophagiccelldeath',s("Any","process","induced","by","ecdysone","that","directly","activates","salivary","gland","programmed","cell","death","during","salivary","gland","histolysis","."),4073024). assertion_content_comment('oboGo_EcdysoneMediatedpolytenechromosomepuffing',s("The","decondensing","(","loosening",")","and","swelling","of","the","chromosomal","sites","of","hormone-responsive","genes","on","polytene","chromosomes","in","response","to","increased","production","of","the","steroid","hormone","20-hydroxyecdysone","(","ecdysone",")","in","Drosophila","larvae","approaching","pupation","."),4381691). assertion_content_comment('oboGo_EcdysoneOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","Ecdysone","+","palmitoyl-CoA","=","CoA","+","ecdysone","palmitate","."),4211048). assertion_content_comment('oboGo_EcdysoneReceptorMediatedsignalingpathway',s("The","series","of","molecular","signals","generated","by","ecdysone","binding","to","the","ecdysone","receptor","complex","."),4381701). assertion_content_comment('oboGo_Ecdysteroid22Hydroxylaseactivity',s("Catalysis","of","the","hydroxylation","of","an","ecdysteroid","at","carbon","position","22","."),4317164). assertion_content_comment('oboGo_Ecdysteroid25Hydroxylaseactivity',s("Catalysis","of","the","hydroxylation","of","an","ecdysteroid","at","carbon","position","25",".","Ecdysteroids","are","a","group","of","polyhydroxylated","ketosteroids","which","initiate","post-embryonic","development",",","particularly","metamorphosis",",","in","insects","and","other","arthropods","."),4382817). assertion_content_comment('oboGo_Ecdysteroid2Hydroxylaseactivity',s("Catalysis","of","the","hydroxylation","of","an","ecdysteroid","at","carbon","position","2","."),4317144). assertion_content_comment('oboGo_EcdysteroidUDPGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","ecdysteroid","=","UDP","+","glucosyl-ecdysteroid","."),4210892). assertion_content_comment('oboGo_EcdysteroidUDPGlucosyludpGlucuronosyltransferaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4210896). assertion_content_comment('oboGo_Echinenone3Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","echinenone","+","a","reduced","electron","acceptor","+","oxygen","=","3-hydroxyechinenone","+","an","oxidized","electron","acceptor","+","H2O","."),4190909). assertion_content_comment('oboGo_EcsitNdufaf1complex',s("Any","large","protein","complex","that","contains","Ecsit","and","NDUFAF1",",","is","located","in","the","mitochondrion",",","and","is","involved","in","the","assembly","of","complex","I","of","the","oxidative","phosphorylation","system",".","In","mammalian","cells",",","three","complexes","of","approximately","500",",","600",",","and","850","kDa","containing","the","45","kDa","isoform","of","Ecsit","and","NDUFAF1","have","been","observed","."),4073193). assertion_content_comment('oboGo_EctoineTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","ectoine","(","out/in",")","=","ADP","+","phosphate","+","ectoine","(","in/out",")"),4337848). assertion_content_comment('oboGo_Edg_1Sphingosine1_PhosphateReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-1","sphingosine","1-phosphate","receptor","."),4322779). assertion_content_comment('oboGo_Edg_2LysophosphatidicAcidReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-2","lysophosphatidic","acid","receptor","."),4322768). assertion_content_comment('oboGo_Edg_3Sphingosine1_PhosphateReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-3","sphingosine","1-phosphate","receptor","."),4322758). assertion_content_comment('oboGo_Edg_4LysophosphatidicAcidReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-4","lysophosphatidic","acid","receptor","."),4322747). assertion_content_comment('oboGo_Edg_5Sphingosine1_PhosphateReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-5","sphingosine","1-phosphate","receptor","."),4322737). assertion_content_comment('oboGo_Edg_6Sphingosine1_PhosphateReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-6","sphingosine","1-phosphate","receptor","."),4322727). assertion_content_comment('oboGo_Edg_7LysophosphatidicAcidReceptorBinding',s("Interacting","selectively","and","non-covalently","with","an","Edg-7","lysophosphatidic","acid","receptor","."),4322705). assertion_content_comment('oboGo_EEGeranyllinaloolsynthaseactivity',s("Catalysis","of","the","reaction",":","all-trans-geranyl-geranyl","diphosphate","+","H2O","=","(","E",",","E",")","-geranyllinalool","+","diphosphate","."),4182102). assertion_content_comment('oboGo_EgasynBetaGlucuronidasecomplex',s("A","protein","complex","that","contains","beta-glucuronidase","and","the","carboxyl","esterase","egasyn",";","formation","of","the","complex","causes","beta-glucuronidase","to","be","retained","in","the","endoplasmic","reticulum","."),4173507). assertion_content_comment('oboGo_EGFRGrb2Soscomplex',s("A","protein","complex","that","contains","the","epidermal","growth","factor","receptor","(","EGFR",")",",","Grb2","and","the","guanine","nucleotide","exchange","factor","Sos","(","or","an","ortholog","thereof",",","such","as","mSos1",")",",","and","is","involved","in","linking","EGFR","activation","to","the","p21-Ras","pathway","."),4176969). assertion_content_comment('oboGo_EGFRShcGrb2Soscomplex',s("A","protein","complex","that","contains","the","epidermal","growth","factor","receptor","(","EGFR",")",",","Grb2",",","the","adaptor","protein","SHC","and","the","guanine","nucleotide","exchange","factor","Sos","(","or","an","ortholog","thereof",",","such","as","mSos1",")",",","and","is","involved","in","linking","EGFR","activation","to","the","p21-Ras","pathway","."),4176959). assertion_content_comment('oboGo_Elastin_2',s("OBSOLETE",".","A","major","structural","protein","of","mammalian","connective","tissues",";","composed","of","one","third","glycine",",","and","also","rich","in","proline",",","alanine",",","and","valine",".","Chains","are","cross-linked","together","via","lysine","residues","."),4361671). assertion_content_comment('oboGo_ElectronTransferringFlavoproteindehydrogenaseactivity',s("Catalysis","of","the","reaction",":","reduced","ETF","+","ubiquinone","=","ETF","+","ubiquinol","."),4211030). assertion_content_comment('oboGo_ElectronTransporterTransferringElectronsFromCoQH2Cytochromecreductasecomplexandcytochromecoxidasecomplexactivity',s("Enables","the","directed","movement","of","electrons","from","the","CoQH2-cytochrome","c","reductase","complex","and","the","cytochrome","c","oxidase","complex","."),4258945). assertion_content_comment('oboGo_ElectronTransporterTransferringElectronsWithinCoQH2Cytochromecreductasecomplexactivity',s("Enables","the","directed","movement","of","electrons","within","the","CoQH2-cytochrome","c","reductase","complex","."),4259047). assertion_content_comment('oboGo_ElevationOfCytosolicCalciumIonConcentrationInvolvedInGProteinsignalingcoupledtoip3secondmessenger',s("Any","process","that","increases","the","concentration","of","calcium","ions","in","the","cytosol","that","contributes","to","the","process","of","G-protein","signaling","coupled","to","IP3","second","messenger","."),4119036). assertion_content_comment('oboGo_Elg1RFCLikecomplex',s("A","pentameric","complex","related","to","replication","factor","C",",","which","loads","the","DNA","polymerase","processivity","factor","proliferating","cell","nuclear","antigen","(","PCNA",")","onto","DNA","and","has","roles","in","telomere","length","regulation","and","other","aspects","of","genome","stability",".","In","Saccharomyces","the","subunits","are","known","as","Elg1p",",","Rfc2p",",","Rfc3p",",","Rfc4p",",","and","Rfc5p","."),4319862). assertion_content_comment('oboGo_ELLEafcomplex',s("A","heterodimeric","protein","complex","that","acts","as","an","RNA","polymerase","II","elongation","factor",";","the","complex","is","conserved","from","yeast","to","humans",",","and","is","present","in","S",".","pombe",",","but","absent","from","S",".","cerevisiae","."),4337574). assertion_content_comment('oboGo_ElongationFactor_2KinaseActivity',s("Catalysis","of","the","reaction",":","ATP","+","[","elongation","factor","2","]","=","ADP","+","[","elongation","factor","2","]","phosphate","."),4202780). assertion_content_comment('oboGo_EmbryonicCameraTypeeyedevelopment',s("The","process","occurring","during","the","embryonic","phase","whose","specific","outcome","is","the","progression","of","the","eye","over","time",",","from","its","formation","to","the","mature","structure","."),3990046). assertion_content_comment('oboGo_EmbryonicCameraTypeeyeformation',s("The","developmental","process","pertaining","to","the","initial","formation","of","a","camera-type","eye","from","unspecified","neurectoderm",".","This","process","begins","with","the","differentiation","of","cells","that","form","the","optic","field","and","ends","when","the","optic","cup","has","attained","its","shape","."),3990053). assertion_content_comment('oboGo_EmbryonicCameraTypeeyemorphogenesis',s("The","process","in","which","the","anatomical","structures","of","the","eye","are","generated","and","organized","during","embryonic","development","."),3990050). assertion_content_comment('oboGo_EmbryonicRetinaMorphogenesisInCameraTypeeye',s("The","process","in","which","the","anatomical","structure","of","the","retina","is","generated","and","organized","in","a","camera-type","eye","during","the","embryonic","life","stage"),4109317). assertion_content_comment('oboGo_Endo_134_Beta_GlucanaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","3-","or","1",",","4-linkages","in","beta-D-glucans","when","the","glucose","residue","whose","reducing","group","is","involved","in","the","linkage","to","be","hydrolysed","is","itself","substituted","at","C-3","."),4344153). assertion_content_comment('oboGo_Endo_14_Beta_XylanaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-xylosidic","linkages","in","xylans","."),4319026). assertion_content_comment('oboGo_EndoAlphaSialidaseactivity',s("Catalysis","of","the","endohydrolysis","of","(","2-","&","gt",";","8",")","-alpha-sialosyl","linkages","in","oligo-","or","poly","(","sialic",")","acids","."),4302376). assertion_content_comment('oboGo_Endobrevin_SNAP_25_Syntaxin_1aComplex',s("A","SNARE","complex","that","contains","endobrevin","(","VAMP8",")",",","SNAP-25",",","and","syntaxin","1a","(","or","orthologs","thereof",")"),4180744). assertion_content_comment('oboGo_Endobrevin_SNAP_25_Syntaxin_2Complex',s("A","SNARE","complex","that","contains","endobrevin","(","VAMP8",")",",","SNAP-25",",","and","syntaxin","2","(","or","orthologs","thereof",")"),4180755). assertion_content_comment('oboGo_Endobrevin_Synaptobrevin2_Alpha_SNAP_NSF_Syntaxin_4Complex',s("A","SNARE","complex","that","contains","endobrevin","(","VAMP8",")",",","synaptobrevin","2","(","VAMP2",")",",","alpha-SNAP",",","NSF",",","and","syntaxin","4","(","or","orthologs","thereof",")"),4176327). assertion_content_comment('oboGo_EndodeoxyribonucleaseActivityProducing3Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","deoxyribonucleic","acids","by","creating","internal","breaks","to","yield","3","'","-phosphomonoesters","."),4204940). assertion_content_comment('oboGo_EndodeoxyribonucleaseActivityProducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","deoxyribonucleic","acids","by","creating","internal","breaks","to","yield","5","'","-phosphomonoesters","."),4204807). assertion_content_comment('oboGo_EndodermalMesodermalcellsignalinginvolvedinheartinduction',s("Any","process","that","mediates","the","transfer","of","information","from","endodermal","cells","to","mesodermal","cells","that","contributes","to","heart","induction","."),4003234). assertion_content_comment('oboGo_EndodermalMesodermalcellsignaling',s("Any","process","that","mediates","the","transfer","of","information","from","endodermal","cells","to","mesodermal","cells","."),4003229). assertion_content_comment('oboGo_EndoFencholsynthaseactivity',s("Catalysis","of","the","reaction",":","geranyl","diphosphate","+","H","(","2",")","O","=","(","-",")","-endo-fenchol","+","diphosphate","."),4266963). assertion_content_comment('oboGo_EndonucleaseActivityActiveWithEitherRiboOrdeoxyribonucleicacidsandproducing3Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","nucleic","acids","by","creating","internal","breaks","to","yield","3","'","-phosphomonoesters","."),4204936). assertion_content_comment('oboGo_EndonucleaseActivityActiveWithEitherRiboOrdeoxyribonucleicacidsandproducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","nucleic","acids","by","creating","internal","breaks","to","yield","5","'","-phosphomonoesters","."),4174722). assertion_content_comment('oboGo_EndonucleolyticCleavageBetweenLSURrnaand5srrnaoftricistronicrrnatranscriptssuRrnalsuRrna5s',s("Endonucleolytic","cleavage","to","separate","a","pre-LSU-rRNA","from","a","pre-5S","rRNA","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","Large","Subunit","(","LSU",")","rRNA",",","and","the","5S","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript",".","Note","that","the","use","of","the","word","tricistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),3976278). assertion_content_comment('oboGo_EndonucleolyticCleavageBetweenSSURrnaandlsuRrnaoftricistronicrrnatranscriptssuRrnalsuRrna5s',s("Endonucleolytic","cleavage","to","separate","a","pre-SSU-rRNA","from","a","pre-LSU-rRNA","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","Large","Subunit","(","LSU",")","rRNA",",","and","the","5S","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript",".","Note","that","the","use","of","the","word","tricistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),3976298). assertion_content_comment('oboGo_EndonucleolyticCleavageIn3EtsoftricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","within","the","3","'","-External","Transcribed","Spacer","(","ETS",")","of","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","In","S",".","cerevisiae",",","endonucleolytic","cleavage","within","the","3","'","-ETS","of","the","pre-RNA",",","which","may","occur","cotranscriptionally",",","is","the","first","step","in","rRNA","processing",",","and","initiates","a","cascade","of","subsequent","processing","and","modification","events","."),4362421). assertion_content_comment('oboGo_EndonucleolyticCleavageIn5EtsoftricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","within","the","5","'","-External","Transcribed","Spacer","(","ETS",")","of","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","Endonucleolytic","cleavage","within","the","5","'","-ETS","of","the","pre-RNA","is","conserved","as","one","of","the","early","steps","of","rRNA","processing","in","all","eukaryotes",",","but","the","specific","position","of","cleavage","is","variable","."),3976445). assertion_content_comment('oboGo_EndonucleolyticCleavageInITS1ToSeparateSSURrnafrom58srrnaandlsuRrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","between","the","SSU-rRNA","and","the","5.8S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976633). assertion_content_comment('oboGo_EndonucleolyticCleavageInITS1UpstreamOf58SRRNAFromTricistronicRRNATranscriptSSURrna58srrnalsuRrna',s("Endonucleolytic","cleavage","within","Internal","Transcribed","Spacer","1","(","ITS1",")","upstream","of","the","5.8S","rRNA","derived","from","an","originally","tricistronic","rRNA","transcript","that","contained","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","In","S",".","cerevisiae",",","this","endonucleolytic","cleavage","within","ITS1","initiates","the","maturation","of","the","LSU","and","the","5.8S","rRNAs","."),3976216). assertion_content_comment('oboGo_EndonucleolyticCleavageOfTetracistronicRRNATranscriptSSURrna58srrna2srrnalsuRrna',s("Endonucleolytic","cleavage","of","a","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","2S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript",".","Primary","ribosomal","RNA","transcripts","with","four","genes",",","in","this","order",",","are","produced","in","the","nuclei","of","D",".","melanogaster","as","well","as","in","those","of","other","dipteran","species","."),3976382). assertion_content_comment('oboGo_EndonucleolyticCleavageOfTetracistronicRRNATranscriptSSURrnalsuRrna45sRrna5sRrna',s("Endonucleolytic","cleavage","of","a","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","Primary","ribosomal","RNA","transcripts","with","four","genes",",","in","this","order",",","are","produced","in","the","chloroplasts","of","vascular","plants",".","Note","that","the","use","of","the","word","tetracistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),4374843). assertion_content_comment('oboGo_EndonucleolyticCleavageOfTricistronicRRNATranscriptSSURrna58srrnalsuRrna',s("Endonucleolytic","cleavage","of","a","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript",".","Primary","ribosomal","RNA","transcripts","with","three","genes",",","in","this","order",",","are","produced","in","the","nuclei","of","many","eukaryotic","species",",","including","S",".","cerevisiae","."),3976212). assertion_content_comment('oboGo_EndonucleolyticCleavageOfTricistronicRRNATranscriptSSURrnalsuRrna5s',s("Endonucleolytic","cleavage","of","a","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","Large","Subunit","(","LSU",")","rRNA",",","and","the","5S","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript",".","For","example",",","primary","ribosomal","RNA","transcripts","containing","three","genes",",","in","this","order",",","are","produced","in","E",".","coli","and","other","prokaryotic","species",".","Note","that","the","use","of","the","word","tricistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),3976275). assertion_content_comment('oboGo_EndonucleolyticCleavageToGenerateMature3EndofssuRrnafromssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","at","the","3","'","-end","of","the","SSU-rRNA","from","an","originally","tricistronic","rRNA","transcript","that","contained","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",",","to","produce","the","mature","end","of","the","SSU-rRNA","."),3976249). assertion_content_comment('oboGo_EndonucleolyticCleavageToGenerateMature5EndofssuRrnafromssuRrna58srrnalsuRrna',s("Endonucleolytic","cleavage","between","the","5","'","-External","Transcribed","Spacer","(","5","'","-ETS",")","and","the","5","'","end","of","the","SSU-rRNA","of","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",",","to","produce","the","mature","end","of","the","SSU-rRNA","."),3976470). assertion_content_comment('oboGo_EndonucleolyticCleaveageBetween45SRRNAAnd5SRRNAOfTetracistronicRRNATranscriptSSURrnalsuRrna45sRrna5sRrna',s("Endonucleolytic","cleavage","between","the","5S","rRNA","and","the","4.5S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","Note","that","the","use","of","the","word","tetracistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),4374873). assertion_content_comment('oboGo_EndonucleolyticCleaveageBetweenLSURrnaand45srrnaoftetracistronicrrnatranscriptssuRrnalsuRrna45sRrna5sRrna',s("Endonucleolytic","cleavage","between","the","LSU-rRNA","and","the","4.5S","rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","Note","that","the","use","of","the","word","tetracistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),4374852). assertion_content_comment('oboGo_EndonucleolyticCleaveageBetweenSSURrnaandlsuRrnaoftetracistronicrrnatranscriptssuRrnalsuRrna45sRrna5sRrna',s("Endonucleolytic","cleavages","between","the","SSU-rRNA","and","the","LSU-rRNA","of","an","rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript",".","These","cleavages","liberate","tRNAs","from","the","polycistronic","transcript","as","well","as","separating","the","SSU","and","LSU","containing","transcript",".","Note","that","the","use","of","the","word","tetracistronic","refers","only","to","the","number","of","mature","rRNA","molecules","which","will","be","produced","from","the","primary","transcript","and","ignores","tRNAs","that","may","also","be","present","within","the","primary","transcript","."),4374915). assertion_content_comment('oboGo_EndoribonucleaseActivityCleavingSiRNAPairedmrna',s("Catalysis","of","the","endonucleolytic","cleavage","of","the","mRNA","in","a","double-stranded","RNA","molecule","formed","by","the","base","pairing","of","an","mRNA","with","an","siRNA",",","yielding","5","'","-phosphomonoesters","."),4174728). assertion_content_comment('oboGo_EndoribonucleaseActivityProducing3Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","ribonucleic","acids","by","creating","internal","breaks","to","yield","3","'","-phosphomonoesters","."),4205047). assertion_content_comment('oboGo_EndoribonucleaseActivityProducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","ribonucleic","acids","by","creating","internal","breaks","to","yield","5","'","-phosphomonoesters","."),4174726). assertion_content_comment('oboGo_EndosomeToLysosomeTransportOfLowDensitylipoproteinparticle',s("The","directed","movement","of","low-density","lipoprotein","particle","from","endosomes","to","lysosomes","."),4154755). assertion_content_comment('oboGo_EndosporeFormingforespore',s("Portion","of","the","cell","formed","during","the","process","of","bacterial","sporulation","that","will","ultimately","become","the","core","of","the","endospore",".","An","endospore","is","a","type","of","dormant","cell","that","is","resistant","to","adverse","conditions","."),4316397). assertion_content_comment('oboGo_EndothelialCellCelladhesion',s("The","attachment","of","an","endothelial","cell","to","another","endothelial","cell","via","adhesion","molecules","."),4172732). assertion_content_comment('oboGo_EndothelialDifferentiationGProteincoupledreceptorbinding',s("Interacting","selectively","and","non-covalently","with","an","endothelial","differentiation","G-protein","coupled","receptor","."),4322702). assertion_content_comment('oboGo_EndothelinAreceptoractivity',s("A","G-protein","coupled","receptor","that","preferentially","binds","endothelin","1","."),4360474). assertion_content_comment('oboGo_EndothelinBreceptoractivity',s("A","G-protein","coupled","receptor","that","binds","all","endothelin","molecules","with","approximately","equal","affinity","."),4383486). assertion_content_comment('oboGo_EndothelinConvertingenzyme1activity',s("OBSOLETE",".","Catalysis","of","the","formation","of","endothelin","1","by","cleavage","of","the","Trp21-Val22","bond","in","the","precursor","."),4305398). assertion_content_comment('oboGo_EndothelinConvertingenzymeactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4305374). assertion_content_comment('oboGo_EnhancerSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","specific","sequence","of","DNA","that","is","part","of","an","enhancer",",","a","transcription","regulatory","region","that","is","somewhat","distal","from","the","core","promoter","and","which","enhances","transcription","from","that","promoter","."),4357765). assertion_content_comment('oboGo_EnoylAcylCarrierProteinreductaseactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","NAD","(","P",")","+","=","trans-2",",","3-dehydroacyl-","[","acyl-carrier","protein","]","+","NAD","(","P",")","H","+","H","+"),4305776). assertion_content_comment('oboGo_EnoylAcylCarrierProteinreductasenadhactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","NAD","+","=","trans-2",",","3-dehydroacyl-","[","acyl-carrier","protein","]","+","NADH","+","H","+"),4208848). assertion_content_comment('oboGo_EnoylAcylCarrierProteinreductasenadphaSpecificactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","NADP","+","=","trans-D2-enoyl-","[","acyl-carrier","protein","]","+","NADPH","+","H","+"),4365870). assertion_content_comment('oboGo_EnoylAcylCarrierProteinreductasenadphbSpecificactivity',s("Catalysis","of","the","reaction",":","acyl-","[","acyl-carrier","protein","]","+","NADP","+","=","trans-2",",","3-dehydroacyl-","[","acyl-carrier","protein","]","+","NADPH","+","H","+"),4208464). assertion_content_comment('oboGo_EnoylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","(","3S",")","-3-hydroxyacyl-CoA","=","trans-2-enoyl-CoA","+","H2O","."),4208937). assertion_content_comment('oboGo_Ent_7_Alpha_HydroxykaurenoateOxidaseActivity',s("Catalysis","of","the","reaction",":","ent-7-alpha-hydroxykaurenoate","+","NADPH","+","H","+","+","O2","=","gibberellin","12-aldehyde","+","NADP","+","+","2","H2O",".","This","is","the","second","of","three","successive","reactions","resulting","in","the","oxidation","of","ent-kaurenoate","(","ent-kaurenoic","acid",")","to","gibberellin","12","(","GA12",")"),4280342). assertion_content_comment('oboGo_Ent_Cassa_1215_DieneSynthaseActivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-cassa-12",",","15-diene","+","diphosphate","."),4360248). assertion_content_comment('oboGo_EntCopalyldiphosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","all-trans-geranylgeranyl","diphosphate","=","ent-copalyl","diphosphate","."),4262148). assertion_content_comment('oboGo_EntIsokaurenesynthaseactivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-isokaurene","+","diphosphate","."),4360091). assertion_content_comment('oboGo_Ent_Kaur_16_En_19_AlOxidaseActivity',s("Catalysis","of","the","reaction",":","NADPH","+","ent-kaur-16-en-19-al","+","oxygen","=","H2O","+","NADP","+","+","ent-kaurenoate","."),4191040). assertion_content_comment('oboGo_Ent_Kaur_16_En_19_OlOxidaseActivity',s("Catalysis","of","the","reaction",":","H","+","+","NADPH","+","ent-kaur-16-en-19-ol","+","oxygen","=","2","H2O","+","NADP","+","+","ent-kaur-16-en-19-al","."),4191134). assertion_content_comment('oboGo_EntKaurenebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","ent-kaurene",".","Ent-kaurene","is","a","tetracyclic","diterpenoid","that","is","a","precursor","of","several","plant","isoprenoids",",","including","gibberellins","."),4338592). assertion_content_comment('oboGo_EntKaurenemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","ent-kaur-16-ene",".","Ent-kaurene","is","a","tetracyclic","diterpenoid","that","is","a","precursor","of","several","plant","isoprenoids",",","including","gibberellins","."),4335578). assertion_content_comment('oboGo_EntKaureneoxidaseactivity',s("Catalysis","of","the","reaction",":","H","+","+","NADPH","+","ent-kaur-16-ene","+","oxygen","=","H2O","+","NADP","+","+","ent-kaur-16-en-19-ol","."),4191125). assertion_content_comment('oboGo_EntKaureneoxidationtokaurenoicacid',s("The","three","successive","oxidations","of","the","4-methyl","group","of","ent-kaurene","to","form","ent-kaur-16-en-19-oate",",","kaurenoic","acid",".","This","process","may","be","carried","out","entirely","by","the","enzyme","ent-kaurene","oxidase","."),4335582). assertion_content_comment('oboGo_EntKaurenesynthaseactivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-kaur-16-ene","+","diphosphate","."),4262191). assertion_content_comment('oboGo_EntKaurenoateoxidaseactivity',s("Catalysis","of","the","reaction",":","ent-kaurenoate","+","NADPH","+","O2","=","ent-7-alpha-hydroxykaurenoate","+","NADP","+","+","H2O",".","This","is","the","first","of","three","successive","reactions","resulting","in","the","oxidation","of","ent-kaurenoate","(","ent-kaurenoic","acid",")","to","gibberellin","12","(","GA12",")"),4280330). assertion_content_comment('oboGo_EntnerDoudoroffpathway',s("A","pathway","that","converts","glucose","to","pyruvate","and","glyceraldehyde-3","phosphate","by","producing","6-phosphogluconate","and","then","dehydrating","it","."),4257701). assertion_content_comment('oboGo_Ent_Pimara_81415_DieneSynthaseActivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-pimara-8","(","14",")",",","15-diene","+","diphosphate","."),4360055). assertion_content_comment('oboGo_Ent_Pimara_91115_DieneSynthaseActivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-pimara-9","(","11",")",",","15-diene","+","diphosphate","."),4192196). assertion_content_comment('oboGo_EntSandaracopimaradienesynthaseactivity',s("Catalysis","of","the","reaction",":","ent-copalyl","diphosphate","=","ent-sandaracopimara-8","(","14",")",",","15-diene","+","diphosphate","."),4360080). assertion_content_comment('oboGo_EnzymeActiveSiteFormationVia1_Phospho_5_Adenosine_L_Histidine',s("The","transient","adenylylation","of","peptidyl-histidine","to","form","1","'","-","(","phospho-5","'","-adenosine",")","-L-histidine","(","otherwise","known","as","tau-AMP-histidine",",","tele-AMP-histidine",")"),4287291). assertion_content_comment('oboGo_EnzymeActiveSiteFormationVia1_Phospho_5_Uridine_L_Histidine',s("The","transient","uridylylation","of","peptidyl-histidine","to","form","1","'","-","(","phospho-5","'","-uridine",")","-L-histidine","(","otherwise","known","as","tau-UMP-histidine",",","tele-UMP-histidine",")"),4287259). assertion_content_comment('oboGo_EnzymeActiveSiteFormationVia1PhosphoLHistidine',s("The","transient","phosphorylation","of","peptidyl-histidine","to","form","1","'","-phospho-L-histidine","(","otherwise","known","as","tau-phosphohistidine",",","tele-phosphohistidine",")"),4279556). assertion_content_comment('oboGo_EnzymeActiveSiteFormationVia3PhosphoLHistidine',s("The","transient","phosphorylation","of","peptidyl-histidine","to","form","3","'","-phospho-L-histidine","(","otherwise","known","as","pi-phosphohistidine",",","pros-phosphohistidine",")"),4279545). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaL_245_Topaquinone',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4279683). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaLAspartic4Phosphoricanhydride',s("The","transient","phosphorylation","of","peptidyl-aspartic","acid","to","form","L-aspartic","4-phosphoric","anhydride","."),4281606). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaLCysteinepersulfide',s("The","modification","of","peptidyl-cysteine","to","form","peptidyl-L-cysteine","persulfide",".","A","persulfurated","cysteine","promotes","active","site","reactivity","in","Azotobacter","vinelandii","Rhodanese","."),4285598). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaLCysteinesulfenicacid',s("The","oxidation","of","peptidyl-cysteine","to","form","peptidyl-L-cysteine","sulfenic","acid",",","found","in","the","active","site","of","NADH","peroxidase",",","nitrile","hydratase",",","and","peptide","methionine","sulfoxide","reductase","."),4279600). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaLCysteinesulfinicacid',s("The","oxidation","of","peptidyl-cysteine","to","form","peptidyl-L-cysteine","sulfinic","acid","."),4279612). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaN6_Phospho_5_Adenosine_L_Lysine',s("The","transient","adenylylation","of","lysine","to","form","N6-","(","phospho-5","'","-adenosine",")","-L-lysine",",","found","in","the","active","site","of","DNA","ligase","and","RNA","ligase","."),4279480). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaN6_Phospho_5_Guanosine_L_Lysine',s("The","transient","guanylylation","of","lysine","to","form","N6-","(","phospho-5","'","-guanosine",")","-L-lysine",",","found","in","the","guanylyltransferase","active","site","of","mRNA","capping","enzyme","."),4279793). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaN6Pyruvicacid2IminylLLysine',s("OBSOLETE",".","The","transient","modification","of","lysine","by","pyruvate","to","form","N6-pyruvic","acid","2-iminyl-L-lysine",",","found","in","the","active","site","of","dihydrodipicolinate","synthase","."),4279303). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaO4PhosphoLTyrosine',s("The","transient","phosphorylation","of","peptidyl-tyrosine","to","form","O-phospho-L-tyrosine","."),4279715). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaO_Phospho_5_Adenosine_L_Threonine',s("The","transient","adenylylation","of","threonine","to","form","N6-","(","phospho-5","'","-adenosine",")","-L-threonine",",","found","in","the","active","site","of","bovine","phosphodiesterase","I","."),4279749). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaOPhosphoLSerine',s("The","transient","phosphorylation","of","peptidyl-serine","to","form","O-phospho-L-serine","."),4279760). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaOPhosphoLThreonine',s("The","transient","phosphorylation","of","peptidyl-threonine","to","form","O-phospho-L-threonine","."),4279726). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaOSulfoLSerine',s("The","transient","sulfation","of","peptidyl-serine","to","form","O-sulfo-L-serine","."),4272967). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaOSulfoLThreonine',s("The","transient","sulfation","of","peptidyl-threonine","to","form","O-sulfo-L-threonine","."),4273022). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaPhospho_5_Guanosine_L_Histidine',s("The","transient","guanylylation","of","peptidyl-histidine","to","form","(","phospho-5","'","-guanosine",")","-L-histidine","."),4299567). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSAcetylLCysteine',s("The","transient","acetylation","of","peptidyl-cysteine","to","form","S-acetyl-L-cysteine","."),4279501). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSAmidinoLCysteine',s("The","transient","amidinylation","of","peptidyl-cysteine","to","form","peptidyl-S-amidino-L-cysteine","."),4357275). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSMethylLCysteine',s("The","transient","methylation","of","peptidyl-cysteine","to","form","S-methyl-L-cysteine","."),4279635). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSPhosphoLCysteine',s("The","transient","phosphorylation","of","peptidyl-cysteine","to","form","S-phospho-L-cysteine","."),4279523). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSSelenylLCysteine',s("OBSOLETE",".","The","transient","selenylation","of","peptidyl-cysteine","to","form","S-selenyl-L-cysteine","."),4285676). assertion_content_comment('oboGo_EnzymeActiveSiteFormationViaSSulfoLCysteine',s("The","transient","sulfation","of","peptidyl-cysteine","to","form","S-sulfo-L-cysteine","."),4280456). assertion_content_comment('oboGo_EnzymeDirectedrrna2OMethylation',s("The","addition","of","methyl","groups","to","the","2","'","-oxygen","atom","of","nucleotide","residues","in","an","rRNA","molecule","during","ribosome","biogenesis","where","the","methylase","specifies","the","site","that","becomes","methylated","without","using","a","guide","RNA","."),4362482). assertion_content_comment('oboGo_EnzymeDirectedrrnapseudouridinesynthesis',s("The","intramolecular","conversion","of","uridine","to","pseudouridine","during","ribosome","biogenesis","where","the","enzyme","specifies","the","site","that","becomes","pseudouridylated","without","using","a","guide","RNA","."),4362510). assertion_content_comment('oboGo_EnzymeThioltranshydrogenaseglutathioneDisulfideactivity',s("Catalysis","of","the","reaction",":","oxidized","glutathione","+","[","xanthine","dehydrogenase","]","=","reduced","glutathione","+","xanthine-oxidase","."),4365523). assertion_content_comment('oboGo_EPhenylitaconylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","E-phenylitaconyl-CoA","+","H2O","=","(","hydroxymethylphenyl",")","succinyl-CoA","."),4273904). assertion_content_comment('oboGo_EpiblastCellExtraembryonicectodermcellsignalinginvolvedinanteriorposterioraxisspecification',s("Any","process","that","mediates","the","transfer","of","information","from","an","epiblast","cell","to","an","extraembryonic","ectoderm","cell","that","contributes","to","the","specification","of","the","anterior/posterior","axis","."),4111133). assertion_content_comment('oboGo_EpicardiumDerivedcardiacendothelialcelldifferentiation',s("The","process","in","which","an","epicardial","cell","acquires","the","specialized","structural","and/or","functional","features","of","a","cardiac","endothelial","cell","."),4194077). assertion_content_comment('oboGo_EpicardiumDerivedcardiacfibroblastcelldevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","an","epicardial-derived","cardiac","fibroblast","over","time",",","from","its","formation","to","the","mature","state",".","A","epicardial-derived","cardiac","fibroblast","is","a","connective","tissue","cell","of","the","heart","that","arises","from","the","epicardium","and","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4114500). assertion_content_comment('oboGo_EpicardiumDerivedcardiacfibroblastcelldifferentiation',s("The","process","in","which","an","epicardial","cell","acquires","the","specialized","structural","and/or","functional","features","of","a","cardiac","fibroblast",".","A","cardiac","fibroblast","is","a","connective","tissue","cell","in","the","heart","which","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4114498). assertion_content_comment('oboGo_EpicardiumDerivedcardiacfibroblastcellfatecommitment',s("The","commitment","of","an","epicardial","cell","to","a","cardiac","fibroblast","cell","fate","and","its","capacity","to","differentiate","into","a","cardiac","fibroblast",".","A","cardiac","fibroblast","is","a","connective","tissue","cell","in","the","heart","which","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4114520). assertion_content_comment('oboGo_EpicardiumDerivedcardiacvascularsmoothmusclecelldevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","a","cardiac","vascular","smooth","muscle","cell","that","was","derived","from","the","epicardium","over","time",",","from","its","formation","to","the","mature","state","."),4113010). assertion_content_comment('oboGo_EpicardiumDerivedcardiacvascularsmoothmusclecelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","cell","derived","from","the","epicardium","acquires","specialized","features","of","a","cardiac","vascular","smooth","muscle","cell",".","A","cardiac","vascular","smooth","muscle","cell","covers","the","heart","vasculature","and","lacks","transverse","striations","in","its","constituent","fibers","."),4113000). assertion_content_comment('oboGo_EpicardiumDerivedcardiacvascularsmoothmusclecellfatecommitment',s("The","commitment","of","an","epicardial","cell","to","a","cardiac","vascular","smooth","muscle","cell","fate","and","its","capacity","to","differentiate","into","a","cardiac","vascular","smooth","muscle","cell","."),4113020). assertion_content_comment('oboGo_EpicardiumDerivedcellmigrationtothemyocardium',s("The","orderly","movement","of","a","cell","that","have","undergone","an","epithelial","to","mesenchymal","transition","from","the","epicardium","into","the","myocardium","."),4194068). assertion_content_comment('oboGo_EpiCedrolsynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","+","H2O","=","epi-cedrol","+","diphosphate","."),4191448). assertion_content_comment('oboGo_EpicuticleOfCollagenAndCuticulinBasedcuticleextracellularmatrix',s("A","lipid-containing","layer","of","cuticle","that","lies","between","the","cortical","layer","and","the","surface","coat",".","An","example","of","this","component","is","found","in","Caenorhabditis","elegans","."),4108847). assertion_content_comment('oboGo_EpidermalGrowthFactorLikemodulecontaininghormonereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4297279). assertion_content_comment('oboGo_EpidermalGrowthFactorReceptorTransactivationByGProteincoupledreceptorsignalingpathway',s("The","process","in","which","an","epidermal","growth","factor","receptor","is","activated","via","signaling","events","from","a","G-protein","coupled","receptor",".","This","is","an","example","of","cross-talk","between","the","EGFR","and","GPCR","signaling","pathways","."),4380058). assertion_content_comment('oboGo_EpiIsozizaenesynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","+",")","-epi-isozizaene","+","diphosphate","."),4191471). assertion_content_comment('oboGo_EpithelialCellCelladhesioninvolvedinepitheliummigration',s("The","attachment","of","an","epithelial","cell","to","another","epithelial","cell","via","adhesion","molecules","that","contributes","to","epithelium","migration","."),4149090). assertion_content_comment('oboGo_EpithelialCellCelladhesion',s("The","attachment","of","an","epithelial","cell","to","another","epithelial","cell","via","adhesion","molecules","."),4149087). assertion_content_comment('oboGo_EpithelialMesenchymalcellsignalinginvolvedinlungdevelopment',s("Any","process","that","results","in","the","transfer","of","information","from","an","epithelial","cell","to","a","mesenchymal","cell","and","contributes","to","the","progression","of","the","lung","over","time","from","its","initial","formation","to","the","mature","organ","."),4156165). assertion_content_comment('oboGo_EpithelialMesenchymalcellsignaling',s("Any","process","that","results","in","the","transfer","of","information","from","an","epithelial","cell","to","a","mesenchymal","cell","where","it","is","interpreted","."),4110657). assertion_content_comment('oboGo_EpithelialMesenchymalsignalinginvolvedinprostateglanddevelopment',s("Any","process","that","results","in","the","transfer","of","information","from","an","epithelial","cell","to","a","mesenchymal","cell","where","it","is","interpreted","and","contributes","to","the","progression","of","the","prostate","gland","over","time","."),4110661). assertion_content_comment('oboGo_EpitheliumMigrationInvolvedInImaginalDiscDerivedwingmorphogenesis',s("The","process","in","which","the","population","of","cells","that","make","up","a","wing","epithelium","undergo","directed","movement","and","contribute","to","imaginal","disc-derived","morphogenesis","."),4151992). assertion_content_comment('oboGo_EpsilonCaprolactamlactamaseactivity',s("Catalysis","of","the","reaction",":","epsilon-caprolactam","+","H2O","=","H","+","+","6-aminohexanoate","."),4274751). assertion_content_comment('oboGo_ERAssociatedmisfoldedproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","misfolded","proteins","transported","from","the","endoplasmic","reticulum","and","targeted","to","cytoplasmic","proteasomes","for","degradation","."),4170211). assertion_content_comment('oboGo_ERAssociatedproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","proteins","transported","from","the","endoplasmic","reticulum","and","targeted","to","cytoplasmic","proteasomes","for","degradation",".","This","process","acts","on","misfolded","proteins","as","well","as","in","the","regulated","degradation","of","correctly","folded","proteins","."),4170202). assertion_content_comment('oboGo_ErbB_2ClassReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","protein-tyrosine","kinase","receptor","Neu/ErbB-2/HER2","."),4217085). assertion_content_comment('oboGo_ErbB_3ClassReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","protein-tyrosine","kinase","receptor","ErbB-3/HER3","."),4214029). assertion_content_comment('oboGo_ERCC4Ercc1complex',s("A","heterodimeric","nucleotide-excision","repair","complex","that","has","endonuclease","activity","specific","for","bubble","structures","characteristic","of","certain","DNA","lesions",".","The","subunits","are","known","as","XPF/ERCC4","and","ERCC1","in","mammals",",","and","Rad1p","and","Rad10p","in","S",".","cerevisiae","."),4175019). assertion_content_comment('oboGo_ERDependentperoxisomeorganization',s("A","process","of","peroxisome","organization","in","which","assembly","or","arrangement","of","constituent","parts","takes","place","in","the","endoplasmic","reticulum","."),4331730). assertion_content_comment('oboGo_ERGolgiintermediatecompartmentmembrane',s("The","lipid","bilayer","surrounding","any","of","the","compartments","of","the","ER-Golgi","intermediate","compartment","system","."),4065852). assertion_content_comment('oboGo_ERGolgiintermediatecompartment',s("A","complex","system","of","membrane-bounded","compartments","located","between","endoplasmic","reticulum","(","ER",")","and","the","Golgi","complex",",","with","a","distinctive","membrane","protein","composition",";","involved","in","ER-to-Golgi","transport","."),4065837). assertion_content_comment('oboGo_ERGolgitransportvesicle',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4221430). assertion_content_comment('oboGo_ErgosterolOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","ergosterol","=","CoA","+","ergosterol","ester","."),4349398). assertion_content_comment('oboGo_ErgosterolUDPGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","sterol","=","UDP","+","O-glucosyl-ergosterol","."),4283393). assertion_content_comment('oboGo_ERMitochondrionmembranecontactsite',s("A","zone","of","apposition","between","endoplasmic-reticulum","and","mitochondrial","membranes",",","structured","by","bridging","complexes",".","These","contact","sites","are","thought","to","facilitate","inter-organelle","calcium","and","phospholipid","exchange","."),4070104). assertion_content_comment('oboGo_ERNuclearsterolresponsepathway',s("The","series","of","molecular","signals","from","the","endoplasmic","reticulum","to","the","nucleus","generated","as","a","consequence","of","sterol","depletion",",","and","resulting","in","the","activation","of","transcription","by","SREBP","."),4013663). assertion_content_comment('oboGo_ERNucleussignalingpathway',s("Any","series","of","molecular","signals","that","conveys","information","from","the","endoplasmic","reticulum","to","the","nucleus",",","usually","resulting","in","a","change","in","transcriptional","regulation","."),4013357). assertion_content_comment('oboGo_ERProteasomeCoreComplexAlphaSubunitcomplex',s("The","subunits","forming","the","outer","ring","of","the","core","complex","of","a","proteasome","located","in","the","endoplasmic","reticulum","of","a","cell","."),4060317). assertion_content_comment('oboGo_ERProteasomeCoreComplexBetaSubunitcomplex',s("The","subunits","forming","the","inner","ring","of","the","core","complex","of","a","proteasome","located","in","the","endoplasmic","reticulum","of","a","cell","."),4060295). assertion_content_comment('oboGo_ErrorFreednarepair',s("OBSOLETE",".","DNA","repair","pathways","that","do","not","increase","the","mutation","rate","above","spontaneous","background","levels",",","e.g",".","excision","and","recombination","pathways","."),4300643). assertion_content_comment('oboGo_ErrorFreepostreplicationdnarepair',s("The","conversion","of","DNA-damage","induced","single-stranded","gaps","into","large","molecular","weight","DNA","via","processes","such","as","template","switching",",","which","does","not","remove","the","replication-blocking","lesions","and","but","does","not","increase","the","endogenous","mutation","rate","."),4300637). assertion_content_comment('oboGo_ErrorFreetranslesionsynthesis',s("The","conversion","of","DNA-damage","induced","single-stranded","gaps","into","large","molecular","weight","DNA","after","replication","by","using","a","specialized","DNA","polymerase","or","replication","complex","to","insert","a","defined","nucleotide","across","the","lesion",".","This","process","does","not","remove","the","replication-blocking","lesions","but","does","not","causes","an","increase","in","the","endogenous","mutation","level",".","For","S",".","cerevisiae",",","RAD30","encodes","DNA","polymerase","eta",",","which","incorporates","two","adenines",".","When","incorporated","across","a","thymine-thymine","dimer",",","it","does","not","increase","the","endogenous","mutation","level","."),4177571). assertion_content_comment('oboGo_ErrorPronednarepair',s("OBSOLETE",".","DNA","repair","pathways","that","tend","to","increase","the","endogenous","mutation","rate","."),4300616). assertion_content_comment('oboGo_ErrorPronetranslesionsynthesis',s("The","conversion","of","DNA-damage","induced","single-stranded","gaps","into","large","molecular","weight","DNA","after","replication","by","using","a","specialized","DNA","polymerase","or","replication","complex","to","insert","a","defined","nucleotide","across","the","lesion",".","This","process","does","not","remove","the","replication-blocking","lesions","and","causes","an","increase","in","the","endogenous","mutation","level",".","For","example",",","in","E",".","coli",",","a","low","fidelity","DNA","polymerase",",","pol","V",",","copies","lesions","that","block","replication","fork","progress",".","This","produces","mutations","specifically","targeted","to","DNA","template","damage","sites",",","but","it","can","also","produce","mutations","at","undamaged","sites","."),4300610). assertion_content_comment('oboGo_ERToGolgiVesicleMediatedtransport',s("The","directed","movement","of","substances","from","the","endoplasmic","reticulum","(","ER",")","to","the","Golgi",",","mediated","by","COP","II","vesicles",".","Small","COP","II","coated","vesicles","form","from","the","ER","and","then","fuse","directly","with","the","cis-Golgi",".","Larger","structures","are","transported","along","microtubules","to","the","cis-Golgi","."),4004921). assertion_content_comment('oboGo_Erythro_3_HydroxyaspartateAmmonia_LyaseActivity',s("Catalysis","of","the","reaction",":","erythro-3-hydroxy-L-aspartate","=","NH3","+","oxaloacetic","acid","."),4370228). assertion_content_comment('oboGo_Erythrose_4_PhosphateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","D-erythrose","4-phosphate","+","H","(","2",")","O","+","NAD","(","+",")","=","4-phospho-D-erythronate","+","2","H","(","+",")","+","NADH","."),4384701). assertion_content_comment('oboGo_ESCRT0complex',s("A","protein","complex","required","for","the","recycling","of","Golgi","proteins",",","formation","of","lumenal","membranes","and","sorting","of","ubiquitinated","proteins","into","those","membranes",".","This","complex","includes","Vps1p","and","Hse1p","in","yeast","and","the","Hrs","and","STAM","proteins","in","mammals","."),4341135). assertion_content_comment('oboGo_EsculinBetaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","glucosidic","link","in","esculin","."),4182425). assertion_content_comment('oboGo_EstablishmentOfBloodBrainbarrier',s("Establishment","of","the","barrier","between","the","blood","and","the","brain",".","The","cells","in","the","brain","are","packed","tightly","together","preventing","the","passage","of","most","molecules","from","the","blood","into","the","brain",".","Only","lipid","soluble","molecules","or","those","that","are","actively","transported","can","pass","through","the","blood-brain","barrier","."),4039562). assertion_content_comment('oboGo_EstablishmentOfBloodNervebarrier',s("The","establishment","of","the","barrier","between","the","perineurium","of","peripheral","nerves","and","the","vascular","endothelium","of","endoneurial","capillaries",".","The","perineurium","acts","as","a","diffusion","barrier",",","but","ion","permeability","at","the","blood-nerve","barrier","is","still","higher","than","at","the","blood-brain","barrier","."),4014766). assertion_content_comment('oboGo_EstablishmentOfChromatinSilencingAtSilentMatingTypecassette',s("The","initial","formation","of","a","transcriptionally","silent","chromatin","structure","such","as","heterochromatin","at","silent","mating-type","loci","."),4083177). assertion_content_comment('oboGo_EstablishmentOfEndothelialBloodBrainbarrier',s("Establishment","of","the","endothelial","barrier","between","the","blood","and","the","brain",".","The","endothelial","cells","in","the","brain","capillaries","are","packed","tightly","together","preventing","the","passage","of","most","molecules","from","the","blood","into","the","brain",".","Only","lipid","soluble","molecules","or","those","that","are","actively","transported","can","pass","through","the","blood-brain","barrier","."),4039576). assertion_content_comment('oboGo_EstablishmentOfEpithelialCellApicalBasalPolarityInvolvedInCameraTypeeyemorphogenesis',s("The","specification","and","formation","of","the","apicobasal","polarity","of","an","epithelial","cell","that","contributes","to","the","shaping","of","a","camera-type","eye","."),4192229). assertion_content_comment('oboGo_EstablishmentOfGlialBloodBrainbarrier',s("Establishment","of","the","glial","barrier","between","the","blood","and","the","brain",".","The","glial","cells","in","the","brain","are","packed","tightly","together","preventing","the","passage","of","most","molecules","from","the","blood","into","the","brain",".","Only","lipid","soluble","molecules","or","those","that","are","actively","transported","can","pass","through","the","blood-brain","barrier","."),4156501). assertion_content_comment('oboGo_EstablishmentOfImaginalDiscDerivedwinghairorientation',s("Orientation","of","hairs","in","the","imaginal","disc-derived","wing","along","a","proximal-distal","axis",",","such","that","each","cell","of","the","wing","produces","one","wing","hair","which","points","in","a","distal","direction","."),3982591). assertion_content_comment('oboGo_EstablishmentOfImprintingAtMatingTypelocus',s("The","initial","formation","of","a","stable","single-strand","DNA","lesion","that","triggers","programmed","gene","conversion","at","the","mating-type","locus",",","thereby","restricting","mating-type","interconversion","to","one","of","the","two","sister","chromatids","during","DNA","replication","."),4128801). assertion_content_comment('oboGo_EstablishmentOfMitochondrionLocalizationMicrotubuleMediated',s("The","directed","movement","of","the","mitochondrion","to","a","specific","location",",","by","a","process","involving","microtubules","."),4353807). assertion_content_comment('oboGo_Estradiol17AlphaDehydrogenaseactivity',s("Catalysis","of","the","reaction",":","estradiol-17-alpha","+","NAD","(","P",")","+","=","estrone","+","NAD","(","P",")","H","+","H","+"),4376371). assertion_content_comment('oboGo_Estradiol17BetaDehydrogenaseactivity',s("Catalysis","of","the","reaction",":","estradiol-17-beta","+","NADP","+","=","estrone","+","NADPH","+","H","+"),4208983). assertion_content_comment('oboGo_Estradiol6BetaMonooxygenaseactivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","estradiol-17beta","+","O","(","2",")","=","6beta-hydroxyestradiol-17beta","+","A","+","H","(","2",")","O","."),4376278). assertion_content_comment('oboGo_EthanolAcetatefermentationtobutyrateandcaproate',s("The","anaerobic","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","ethanol","and","acetate","to","butyrate","and","caproate",",","yielding","energy","in","the","form","of","ATP","."),4244800). assertion_content_comment('oboGo_EthanolamineAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","ethanolamine","=","acetaldehyde","+","NH3","."),4250089). assertion_content_comment('oboGo_EthanolamineAmmoniaLyasecomplex',s("An","enzyme","complex","that","catalyzes","the","breakdown","of","ethanolamine","to","form","acetaldehyde","and","ammonia","."),4260247). assertion_content_comment('oboGo_EthanolamineContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","ethanolamine","(","2-aminoethanol",")","and","compounds","derived","from","it","."),3981695). assertion_content_comment('oboGo_EthanolaminePhosphatecytidylyltransferaseactivity',s("Catalysis","of","the","reaction",":","CTP","+","ethanolamine","phosphate","=","diphosphate","+","CDP-ethanolamine","."),4209033). assertion_content_comment('oboGo_EthanolaminePhosphatephosphoLyaseactivity',s("Catalysis","of","the","reaction",":","H","(","2",")","O","+","phosphoethanolamine","=","acetaldehyde","+","NH","(","4",")","(","+",")","+","phosphate","."),4266053). assertion_content_comment('oboGo_EthyleneBiosynthesisInvolvedInJasmonicAcidAndEthyleneDependentsystemicresistance',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","ethylene","(","C2-H4",",","ethene",")",",","occurring","as","part","of","the","process","of","jasmonic","acid","and","ethylene-dependent","systemic","resistance","."),4093284). assertion_content_comment('oboGo_EthyleneMediatedactivationofappressoriumformation',s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","symbiont","ethylene-mediated","signal","transduction","during","appressorium","formation","on","or","near","its","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153831). assertion_content_comment('oboGo_EukaryoticElongationFactor_2KinaseActivatorActivity',s("Increases","the","activity","of","the","enzyme","eukaryotic","elongation","factor-2","kinase","."),4316679). assertion_content_comment('oboGo_EukaryoticElongationFactor_2KinaseRegulatorActivity',s("Modulates","the","activity","of","the","enzyme","eukaryotic","elongation","factor-2","kinase","."),4316656). assertion_content_comment('oboGo_EvasionOrToleranceByOrganismOfSymbiontProducednitricoxide',s("OBSOLETE",".","The","process","by","which","an","organism","avoids","the","effects","of","nitric","oxide","produced","as","a","defense","response","by","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190368). assertion_content_comment('oboGo_EvasionOrToleranceByOrganismOfSymbiontProducedphytoalexins',s("OBSOLETE",".","The","process","by","which","an","organism","avoids","the","effects","of","phytoalexins","produced","as","a","defense","response","by","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190355). assertion_content_comment('oboGo_EvasionOrToleranceByOrganismOfSymbiontProducedreactiveoxygenspecies',s("OBSOLETE",".","The","process","by","which","an","organism","avoids","the","effects","of","reactive","oxygen","species","produced","as","a","defense","response","by","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190889). assertion_content_comment('oboGo_EvasionOrToleranceBySymbiontOfHostProducednitricoxide',s("The","process","in","which","an","organism","avoids","the","effects","of","nitric","oxide","produced","as","a","defense","response","by","the","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4195523). assertion_content_comment('oboGo_EvasionOrToleranceBySymbiontOfHostProducedphytoalexins',s("The","process","in","which","an","organism","avoids","the","effects","of","phytoalexins","produced","as","a","defense","response","by","the","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4195540). assertion_content_comment('oboGo_EvasionOrToleranceBySymbiontOfHostProducedreactiveoxygenspecies',s("The","process","in","which","an","organism","avoids","the","effects","of","reactive","oxygen","species","produced","as","a","defense","response","by","the","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4195500). assertion_content_comment('oboGo_ExcitatoryExtracellularLigandGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","a","specific","extracellular","excitatory","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts",".","Excitatory","ligands",",","such","as","acetylcholine","or","glutamate",",","open","cation-selective","channels","."),4198567). assertion_content_comment('oboGo_Exo_14_Alpha_D_GlucanLyaseActivity',s("Catalysis","of","the","reaction",":","linear","alpha-glucan","=","1",",","5-anhydro-D-fructose","+","beta-D-glucose","."),4369388). assertion_content_comment('oboGo_ExoAlphaSialidaseactivity',s("Catalysis","of","the","hydrolysis","of","alpha-","(","2-","&","gt",";","3",")","-",",","alpha-","(","2-","&","gt",";","6",")","-",",","alpha-","(","2-","&","gt",";","8",")","-glycosidic","linkages","of","terminal","sialic","residues","in","oligosaccharides",",","glycoproteins",",","glycolipids",",","colominic","acid","and","synthetic","substrates","."),4208730). assertion_content_comment('oboGo_ExodeoxyribonucleaseActivityProducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","deoxyribonucleic","acids","by","removing","nucleotide","residues","from","the","3","'","or","5","'","end","to","yield","5","'","phosphomonoesters","."),4183312). assertion_content_comment('oboGo_ExonExonjunctioncomplex',s("A","multi-subunit","complex","deposited","by","the","spliceosome","upstream","of","messenger","RNA","exon-exon","junctions",".","The","exon-exon","junction","complex","provides","a","binding","platform","for","factors","involved","in","mRNA","export","and","nonsense-mediated","mRNA","decay","."),4382148). assertion_content_comment('oboGo_ExonucleaseActivityActiveWithEitherRiboOrdeoxyribonucleicacidsandproducing3Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","nucleic","acids","by","removing","nucleotide","residues","from","the","3","'","or","5","'","end","to","yield","3","'","phosphomonoesters","."),4301472). assertion_content_comment('oboGo_ExonucleaseActivityActiveWithEitherRiboOrdeoxyribonucleicacidsandproducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","nucleic","acids","by","removing","nucleotide","residues","from","the","3","'","or","5","'","end","to","yield","5","'","phosphomonoesters","."),4183309). assertion_content_comment('oboGo_ExonucleolyticNuclearTranscribedmrnacatabolicprocessinvolvedindeadenylationDependentdecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","that","occurs","when","the","ends","are","not","protected","by","the","3","'","-poly","(","A",")","tail","."),4096392). assertion_content_comment('oboGo_ExonucleolyticNuclearTranscribedmrnacatabolicprocessinvolvedindeadenylationIndependentdecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","that","occurs","when","the","ends","are","not","protected","by","the","5","'","-cap","."),4175864). assertion_content_comment('oboGo_ExonucleolyticNuclearTranscribedmrnacatabolicprocessinvolvedinendonucleolyticcleavageDependentdecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","that","occurs","when","the","ends","are","not","protected","by","the","5","'","-cap","."),4096417). assertion_content_comment('oboGo_ExonucleolyticTrimmingToGenerateMature3Endof58srrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Exonucleolytic","digestion","of","a","pre-rRNA","molecule","to","generate","the","mature","3","'","-end","of","a","5.8S","rRNA","molecule","derived","from","an","originally","tricistronic","pre-rRNA","transcript","that","contained","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976144). assertion_content_comment('oboGo_ExonucleolyticTrimmingToGenerateMature5Endof58srrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Exonucleolytic","digestion","of","a","pre-rRNA","molecule","to","generate","the","mature","5","'","-end","of","a","5.8S","rRNA","molecule","derived","from","an","originally","tricistronic","pre-rRNA","transcript","that","contained","the","Small","Subunit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976186). assertion_content_comment('oboGo_ExoPolyAlphaGalacturonosidaseactivity',s("Catalysis","of","the","hydrolysis","of","pectic","acid","from","the","non-reducing","end",",","releasing","digalacturonate","."),4344243). assertion_content_comment('oboGo_ExoribonucleaseActivityProducing3Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","ribonucleic","acids","by","removing","nucleotide","residues","from","the","3","'","or","5","'","end","to","yield","3","'","phosphomonoesters","."),4301874). assertion_content_comment('oboGo_ExoribonucleaseActivityProducing5Phosphomonoesters',s("Catalysis","of","the","hydrolysis","of","ester","linkages","within","ribonucleic","acids","by","removing","nucleotide","residues","from","the","3","'","or","5","'","end","to","yield","5","'","phosphomonoesters","."),4204879). assertion_content_comment('oboGo_ExternalSideOfFungalTypecellwall',s("The","side","of","the","fungal-type","cell","wall","that","is","opposite","to","the","side","that","faces","the","cell","and","its","contents","."),4137206). assertion_content_comment('oboGo_ExtracellularATPGatedcationchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","cation","by","a","channel","that","opens","when","extracellular","ATP","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4198580). assertion_content_comment('oboGo_ExtracellularGlutamateGatedchloridechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","extracellular","glutamate","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4247311). assertion_content_comment('oboGo_ExtracellularGlutamateGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","extracellular","glutamate","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4217933). assertion_content_comment('oboGo_ExtracellularGlycineGatedchloridechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","extracellular","glycine","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4301983). assertion_content_comment('oboGo_ExtracellularGlycineGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","extracellular","glycine","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4301969). assertion_content_comment('oboGo_ExtracellularLigandGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","a","specific","extracellular","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4198565). assertion_content_comment('oboGo_ExtracellularMatrixCellsignaling',s("Any","process","that","mediates","the","transfer","of","information","between","the","extracellular","matrix","and","a","cell","."),4048771). assertion_content_comment('oboGo_ExtracellularMatrixDependentthymocytemigration',s("The","movement","of","a","thymocyte","through","distinct","intrathymic","niches","(","e.g",".","medulla",",","cortex",")",",","where","it","receives","a","unique","set","of","developmental","cues","required","for","T-cell","development",",","dependent","on","extracellular","matrix","components","including","fibronectin",",","collagen","and","laminin","."),4142751). assertion_content_comment('oboGo_ExtracellularMatrixGranulecellsignalinginvolvedinregulationofgranulecellprecursorproliferation',s("The","process","that","mediates","the","transfer","of","information","from","the","extracellular","matrix","to","granule","cell","precursors","resulting","in","a","decrease","in","rate","of","granule","cell","precursor","cell","proliferation","."),4048776). assertion_content_comment('oboGo_ExtracellularMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","bounded","by","a","lipid","bilayer","membrane","and","occurring","outside","the","cell","."),4041899). assertion_content_comment('oboGo_ExtracellularNonMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","not","bounded","by","a","lipid","bilayer","membrane","and","occurring","outside","the","cell","."),4083628). assertion_content_comment('oboGo_ExtraInvasivehyphalmembrane',s("A","host-derived","membrane","surrounding","the","symbiont","invasive","hypha","during","symbiosis","."),4083941). assertion_content_comment('oboGo_ExtraInvasivehyphalspace',s("The","space","between","the","symbiont","plasma","membrane","and","the","extra-invasive","hyphal","membrane","."),4084029). assertion_content_comment('oboGo_ExtrinsicToFungalTypevacuolarmembrane',s("Loosely","bound","to","one","surface","of","the","fungal-type","vacuolar","membrane",",","but","not","integrated","into","the","hydrophobic","region","."),4074278). assertion_content_comment('oboGo_EyeAntennaldiscdevelopment',s("Progression","of","the","eye-antennal","imaginal","disc","over","time",",","from","its","initial","formation","through","to","its","metamorphosis","to","form","adult","structures","including","the","eye",",","antenna",",","head","capsule","and","maxillary","palps","."),4014849). assertion_content_comment('oboGo_EyeAntennaldiscmorphogenesis',s("The","process","in","which","the","anatomical","structures","derived","from","the","eye-antennal","disc","are","generated","and","organized",".","This","includes","the","transformation","of","an","eye-antennal","imaginal","disc","from","a","monolayered","epithelium","in","the","larvae","of","holometabolous","insects","into","recognizable","adult","structures","including","the","eye",",","antenna",",","head","capsule","and","maxillary","palps","."),4017804). assertion_content_comment('oboGo_EyeFieldCellFateCommitmentInvolvedInCameraTypeeyeformation',s("The","commitment","of","neurectodermal","cells","to","cells","of","the","eye","field","and","their","capacity","to","differentiate","into","eye","field","cells",".","Eye","field","cells","are","neurectodermal","cells","that","will","form","the","optic","placode","."),4114144). assertion_content_comment('oboGo_EyelidDevelopmentInCameraTypeeye',s("The","progression","of","the","eyelid","in","a","camera-type","eye","from","its","formation","to","the","mature","state",".","The","eyelid","is","a","membranous","cover","that","helps","protect","and","lubricate","the","eye","."),4113373). assertion_content_comment('oboGo_F4200metabolicprocess',s("The","chemical","reactions","and","pathways","involving","F420-0","(","5-O-","{","[","(","1S",")","-1-carboxyethoxy","]","(","hydroxy",")","phosphoryl","}","-1-deoxy-1-","(","8-hydroxy-2",",","4-dioxo-2H-pyrimido","[","4",",","5-b","]","quinolin-10","(","4H",")","-yl",")","-D-ribitol",")",",","the","fragment","of","coenzyme","F420","remaining","after","formal","hydrolytic","removal","of","all","of","the","glutamate","residues","."),4191751). assertion_content_comment('oboGo_F420_Independent510_Methenyl_5678_TetrahydromethanopterinDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","N5",",","N10-methenyltetrahydromethanopterin","+","H2","=","N5",",","N10-methylenetetrahydromethanopterin","."),4278152). assertion_content_comment('oboGo_FActincappingactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4193205). assertion_content_comment('oboGo_FActincappingproteincomplex',s("A","heterodimer","consisting","of","alpha","and","beta","subunits","that","binds","to","and","caps","the","barbed","ends","of","actin","filaments",",","thereby","regulating","the","polymerization","of","actin","monomers","but","not","severing","actin","filaments","."),4008393). assertion_content_comment('oboGo_FADAmplyasecyclizingactivity',s("Catalysis","of","the","reaction",":","FAD","=","AMP","+","riboflavin","cyclic-4","'",",","5","'","-phosphate","."),4360658). assertion_content_comment('oboGo_FANCMMhfcomplex',s("A","protein","complex","contains","the","proteins","FANCM","and","MHF",",","or","their","orthologs",",","plays","an","essential","role","in","DNA","remodeling",",","protects","replication","forks",",","and","is","conserved","in","eukaryotes","."),4170924). assertion_content_comment('oboGo_FarnesoicAcidOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","farnesoic","acid","+","S-adenosyl-methionine","=","methyl","farnesoate","+","S-adenosyl-L-homocysteine","."),4236365). assertion_content_comment('oboGo_Farnesol2Isomeraseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesol","=","2-cis",",","6-trans-farnesol","."),4376294). assertion_content_comment('oboGo_FarnesylDiphosphatefarnesyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","farnesyl","diphosphate","=","diphosphate","+","presqualene","diphosphate","."),4208923). assertion_content_comment('oboGo_FarnesylDiphosphatefarnesyltransferasecomplex',s("OBSOLETE",".","A","complex","that","possesses","farnesyl-diphosphate","farnesyl","transferase","activity","."),4246772). assertion_content_comment('oboGo_FarRedlightphotoreceptoractivity',s("The","function","of","absorbing","and","responding","to","electromagnetic","radiation","with","a","wavelength","of","approximately","730nm",".","The","response","may","involve","a","change","in","conformation","."),4321797). assertion_content_comment('oboGo_FarRedlightsignalingpathway',s("The","series","of","molecular","signals","initiated","upon","sensing","of","far","red","light","by","a","photoreceptor","molecule",".","Far","red","light","is","electromagnetic","radiation","of","wavelength","700-800nm",".","An","example","of","this","response","is","seen","at","the","beginning","of","many","plant","species","developmental","stages",".","These","include","germination",",","and","the","point","when","cotyledon","expansion","is","triggered",".","In","certain","species","these","processes","take","place","in","response","to","absorption","of","red","light","by","the","pigment","molecule","phytochrome",",","but","the","signal","can","be","reversed","by","exposure","to","far","red","light",".","During","the","initial","phase","the","phytochrome","molecule","is","only","present","in","the","red","light","absorbing","form",",","but","on","absorption","of","red","light","it","changes","to","a","far","red","light","absorbing","form",",","triggering","progress","through","development",".","An","immediate","short","period","of","exposure","to","far","red","light","entirely","returns","the","pigment","to","its","initial","state","and","prevents","triggering","of","the","developmental","process",".","A","thirty","minute","break","between","red","and","subsequent","far","red","light","exposure","renders","the","red","light","effect","irreversible",",","and","development","then","occurs","regardless","of","whether","far","red","light","exposure","subsequently","occurs","."),4330018). assertion_content_comment('oboGo_FasActivatedserinethreoninekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","Fas-activated","serine/threonine","protein","=","ADP","+","Fas-activated","serine/threonine","phosphoprotein","."),4343609). assertion_content_comment('oboGo_FasciclinLikearabinogalactanproteinmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","the","cell","wall","arabinogalactan","II","glycoprotein","variant","which","contains","both","an","arabinogalactan","protein","(","AGP",")","motif","and","a","fasciclin","domain","."),4332981). assertion_content_comment('oboGo_FastTwitchskeletalmusclefibercontraction',s("A","process","in","which","force","is","generated","within","fast-twitch","skeletal","muscle","tissue",",","resulting","in","a","change","in","muscle","geometry",".","Force","generation","involves","a","chemo-mechanical","energy","conversion","step","that","is","carried","out","by","the","actin/myosin","complex","activity",",","which","generates","force","through","ATP","hydrolysis",".","The","fast-twitch","skeletal","muscle","is","characterized","by","fast","time","parameters",",","high","force","development","and","fatiguability","."),4058135). assertion_content_comment('oboGo_FatSolublevitaminbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","any","of","a","diverse","group","of","vitamins","that","are","soluble","in","organic","solvents","and","relatively","insoluble","in","water","."),4035187). assertion_content_comment('oboGo_FatSolublevitamincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","any","of","a","diverse","group","of","vitamins","that","are","soluble","in","organic","solvents","and","relatively","insoluble","in","water","."),4312557). assertion_content_comment('oboGo_FatSolublevitaminmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","of","any","of","a","diverse","group","of","vitamins","that","are","soluble","in","organic","solvents","and","relatively","insoluble","in","water","."),4035148). assertion_content_comment('oboGo_FattyAcidAlphaHydroxylaseactivity',s("Catalysis","of","the","conversion","of","a","fatty","acid","to","an","alpha-hydroxylated","fatty","acid",".","A","hydroxyl","group","is","added","to","the","second","carbon",",","counted","from","the","carboxyl","end",",","of","a","fatty","acid","chain","."),4180951). assertion_content_comment('oboGo_FattyAcidAlphaOxidation',s("A","metabolic","pathway","by","which","3-methyl","branched","fatty","acids","are","degraded",".","These","compounds","are","not","degraded","by","the","normal","peroxisomal","beta-oxidation","pathway",",","because","the","3-methyl","blocks","the","dehydrogenation","of","the","hydroxyl","group","by","hydroxyacyl-CoA","dehydrogenase",".","The","3-methyl","branched","fatty","acid","is","converted","in","several","steps","to","pristenic","acid",",","which","can","then","feed","into","the","beta-oxidative","pathway","."),4361304). assertion_content_comment('oboGo_FattyAcidBetaOxidationmultienzymecomplex',s("A","complex","that","includes","the","long-chain","3-hydroxyacyl-CoA","dehydrogenase","and","long-chain","enoyl-CoA","hydratase","activities","in","two","subunits","(","alpha","and","beta",")",",","catalyzing","two","steps","of","the","fatty","acid","beta-oxidation","cycle","within","the","mitochondrial","matrix","."),4034281). assertion_content_comment('oboGo_FattyAcidBetaOxidation',s("A","fatty","acid","oxidation","process","that","results","in","the","complete","oxidation","of","a","long-chain","fatty","acid",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","occurs","by","successive","cycles","of","reactions","during","each","of","which","the","fatty","acid","is","shortened","by","a","two-carbon","fragment","removed","as","acetyl","coenzyme","A",";","the","cycle","continues","until","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4057948). assertion_content_comment('oboGo_FattyAcidBetaOxidationunsaturatedevennumberepimerasepathway',s("A","fatty","acid","beta-oxidation","pathway","by","which","fatty","acids","having","cis-double","bonds","on","even-numbered","carbons","are","degraded",".","In","this","pathway",",","the","intermediate","2",",","4-dienoyl-CoA","is","converted","to","cis-2-enoyl-CoA","through","one","more","cycle","of","the","core","beta-oxidation","pathway",".","Cis-2-enoyl-CoA","cannot","be","completely","degraded","via","the","core","beta-oxidation","pathway","because","hydratation","of","cis-2-enoyl-CoA","yields","D-3-hydroxyacyl-CoA",",","which","is","not","a","substrate","for","3-hydroxylacyl-CoA","dehydrogenase",".","Cis-2-enoyl-CoA","must","enter","the","so-called","epimerase","pathway",",","which","involves","converting","D-3-hydroxyacyl-CoA","to","L-3-hydroxyacyl-CoA","by","3-hydroxylacyl-CoA","epimerase","or","by","two","stereo-specific","enoyl-CoA","hydratases",".","L-3-hydroxyacyl-CoA","then","returns","to","the","core","beta-oxidation","pathway",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340930). assertion_content_comment('oboGo_FattyAcidBetaOxidationunsaturatedevennumberreductaseisomerasepathway',s("A","fatty","acid","beta-oxidation","pathway","by","which","fatty","acids","having","cis-double","bonds","on","even-numbered","carbons","are","degraded",".","In","this","pathway",",","the","intermediate","2",",","4-dienoyl-CoA","is","converted","to","trans-2-enoyl-CoA","by","2",",","4-dienoyl-CoA","reductase","and","delta3-delta2-enoyl-CoA","isomerase",";","trans-2-enoyl-CoA","returns","to","the","core","beta-oxidation","pathway","for","further","degradation",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340906). assertion_content_comment('oboGo_FattyAcidBetaOxidationunsaturatedevennumber',s("A","fatty","acid","beta-oxidation","pathway","by","which","fatty","acids","having","cis-double","bonds","on","even-numbered","carbons","are","degraded",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340904). assertion_content_comment('oboGo_FattyAcidBetaOxidationunsaturatedoddnumber',s("A","fatty","acid","beta-oxidation","pathway","by","which","fatty","acids","having","cis-double","bonds","on","odd-numbered","carbons","are","degraded",".","In","this","pathway",",","a","cis-3-enoyl-CoA","is","generated","by","the","core","beta-oxidation","pathway",",","and","then","converted","to","a","trans-2-enoyl-CoA",",","which","can","return","to","the","core","beta-oxidation","pathway","for","complete","degradation",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340939). assertion_content_comment('oboGo_FattyAcidBetaOxidationusingacylCoadehydrogenase',s("A","fatty","acid","beta-oxidation","pathway","in","which","the","initial","step","of","each","oxidation","cycle",",","which","converts","an","acyl-CoA","to","a","trans-2-enoyl-CoA",",","is","catalyzed","by","acyl-CoA","dehydrogenase",";","the","electrons","removed","by","oxidation","pass","through","the","respiratory","chain","to","oxygen","and","leave","H2O","as","the","product",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340957). assertion_content_comment('oboGo_FattyAcidBetaOxidationusingacylCoaoxidase',s("A","fatty","acid","beta-oxidation","pathway","in","which","the","initial","step",",","which","converts","an","acyl-CoA","to","a","trans-2-enoyl-CoA",",","is","catalyzed","by","acyl-CoA","oxidase",";","the","electrons","removed","by","oxidation","pass","directly","to","oxygen","and","produce","hydrogen","peroxide",",","which","is","cleaved","by","peroxisomal","catalases",".","Fatty","acid","beta-oxidation","begins","with","the","addition","of","coenzyme","A","to","a","fatty","acid",",","and","ends","when","only","two","or","three","carbons","remain","(","as","acetyl-CoA","or","propionyl-CoA","respectively",")"),4340948). assertion_content_comment('oboGo_FattyAcidOmegaOxidation',s("A","fatty","acid","oxidation","process","in","which","the","methyl","group","at","the","end","of","the","fatty","acid","molecule","(","the","omega","carbon",")","is","first","oxidized","to","a","hydroxyl","group",",","then","to","an","oxo","group",",","and","finally","to","a","carboxyl","group",".","The","long","chain","dicarboxylates","derived","from","omega-oxidation","then","enter","the","beta-oxidation","pathway","for","further","degradation","."),4333427). assertion_content_comment('oboGo_FattyAcidOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","a","fatty","acid","=","S-adenosyl-L-homocysteine","+","a","fatty","acid","methyl","ester","."),4308920). assertion_content_comment('oboGo_FattyAcylCoabinding',s("Interacting","selectively","and","non-covalently","with","acyl-CoA",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","a","fatty","acyl","group","."),4218962). assertion_content_comment('oboGo_FattyAcylCoabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","fatty-acyl-CoA",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","a","fatty-acyl","group","."),4362091). assertion_content_comment('oboGo_FattyAcylCoametabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","fatty-acyl-CoA",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","thiolester","linkage","with","a","fatty-acyl","group","."),4362086). assertion_content_comment('oboGo_FattyAcylCoareductasealcoholFormingactivity',s("Catalysis","of","the","reaction",":","a","very","long","chain","fatty","acyl-CoA","+","NADPH","=","a","very","long","chain","primary","alcohol","+","NADP","+","CoA","."),4182071). assertion_content_comment('oboGo_FattyAcylCoasynthaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","n","malonyl-CoA","+","2n","NADH","+","2n","NADPH","+","4n","H","+","=","a","long-chain","acyl-CoA","+","n","CoA","+","n","CO2","+","2n","NAD","+","+","2n","NADP","+"),4208692). assertion_content_comment('oboGo_FattyAcylCoasynthasecomplex',s("A","protein","complex","that","possesses","fatty-acyl-CoA","synthase","activity","."),4221796). assertion_content_comment('oboGo_FattyAcylCoatransporteractivity',s("Enables","the","directed","movement","of","a","fatty","acyl","CoA","group","into",",","out","of","or","within","a","cell",",","or","between","cells",".","A","fatty","acyl","CoA","group","is","any","acyl","group","derived","from","a","fatty","acid","with","a","coenzyme","A","group","attached","to","it","."),4216189). assertion_content_comment('oboGo_FattyAcylCoatransport',s("The","directed","movement","of","fatty","acyl","coenzyme","A","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Fatty","acyl","coenzyme","A","is","an","acyl","group","linked","to","3","'","-phosphoadenosine-","(","5","'",")","diphospho","(","4","'",")","pantatheine","(","coenzyme","A",")"),4294496). assertion_content_comment('oboGo_FattyAcylEthylEstersynthaseactivity',s("Catalysis","of","the","reaction",":","a","long-chain-acyl","ethyl","ester","+","H2O","=","a","long-chain","carboxylic","acid","+","ethanol","."),4309614). assertion_content_comment('oboGo_FattyAcylgrouptransporteractivity',s("Enables","the","directed","movement","of","a","fatty","acyl","group","into",",","out","of","or","within","a","cell",",","or","between","cells",".","A","fatty","acyl","group","is","any","acyl","group","derived","from","a","fatty","acid","."),4216185). assertion_content_comment('oboGo_FattyAcylgrouptransport',s("The","directed","movement","of","fatty","acyl","groups","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","A","fatty","acyl","group","is","any","acyl","group","derived","from","a","fatty","acid","."),4294486). assertion_content_comment('oboGo_FcAlphareceptoricomplex',s("A","protein","complex","composed","of","an","Fc-alpha","R","alpha","chain","and","an","Fc-epsilon","RI","gamma","chain","dimer","with","or","without","additional","signaling","components",".","The","complex","functions","primarily","as","an","activating","receptor","for","IgA","."),4336899). assertion_content_comment('oboGo_FcEpsilonreceptoricomplex',s("A","protein","complex","composed","of","an","Fc-epsilon","RI","alpha","chain","and","an","Fc-epsilon","RI","gamma","chain","dimer","with","or","without","an","Fc-episilon","RI","beta","chain","and","additional","signaling","components",".","The","complex","functions","primarily","as","an","activating","receptor","for","IgE","."),4336911). assertion_content_comment('oboGo_FcGammareceptoricomplexbinding',s("Interacting","selectively","and","non-covalently","with","one","or","more","specific","sites","on","the","Fc-gamma","receptor","I","complex",".","The","complex","functions","primarily","as","an","activating","receptor","for","IgG","."),4348499). assertion_content_comment('oboGo_FcGammareceptoricomplex',s("A","protein","complex","composed","of","an","Fc-gamma","RI","alpha","chain","and","an","Fc-epsilon","RI","gamma","chain","dimer","with","or","without","additional","signaling","components",".","The","complex","functions","primarily","as","an","activating","receptor","for","IgG","."),4347480). assertion_content_comment('oboGo_FcGammareceptoriiicomplex',s("A","protein","complex","composed","of","an","Fc-gamma","RIII","alpha","chain","and","an","Fc-epsilon","RI","gamma","chain","dimer","with","or","without","an","Fc-epsilon","RI","beta","chain","and","additional","signaling","components",".","The","complex","functions","primarily","as","an","activating","receptor","for","IgG","."),4347492). assertion_content_comment('oboGo_FearInducedaggressivebehavior',s("Aggressive","behavior","associated","with","attempts","to","flee","from","a","threat","."),4375547). assertion_content_comment('oboGo_FemaleGermLinecystencapsulation',s("Formation","of","a","single","follicular","epithelium","around","the","germ-line","derived","cells","of","a","cyst","formed","in","the","female","gonad","."),4051853). assertion_content_comment('oboGo_FemaleGermLinecystformation',s("Formation","of","a","cluster","of","germ-line","cells",",","in","the","female","gonad",",","derived","from","a","single","founder","cell",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4051810). assertion_content_comment('oboGo_FemaleGermLinesexdetermination',s("The","determination","of","sex","and","sexual","phenotype","in","a","female","organism","'","s","germ","line","."),4236527). assertion_content_comment('oboGo_FemaleGermLinestemcelldivision',s("The","self-renewing","division","of","a","germline","stem","cell","in","the","female","gonad",",","to","produce","a","daughter","stem","cell","and","a","daughter","germ","cell",",","which","will","divide","to","form","the","female","gametes","."),4104297). assertion_content_comment('oboGo_FeminizationOfHermaphroditicGermLine',s("The","determination","of","female","sex","and","sexual","phenotype","in","the","germ-line","of","the","hermaphrodite","."),4232558). assertion_content_comment('oboGo_Ferredoxin_NADPReductaseActivity_1',s("Catalysis","of","the","reaction",":","reduced","ferredoxin","+","NAD","(","P",")","+","=","oxidized","ferredoxin","+","NAD","(","P",")","H","+","H","+"),4248775). assertion_content_comment('oboGo_FerredoxinNadpreductaseactivity',s("Catalysis","of","the","reaction",":","reduced","ferredoxin","+","NADP","+","=","oxidized","ferredoxin","+","NADPH","+","H","+"),4208621). assertion_content_comment('oboGo_FerredoxinNadreductaseactivity',s("Catalysis","of","the","reaction",":","reduced","ferredoxin","+","NAD","+","=","oxidized","ferredoxin","+","NADH","+","H","+"),4249567). assertion_content_comment('oboGo_FerredoxinNitratereductaseactivity',s("Catalysis","of","the","reaction",":","nitrite","+","H2O","+","2","oxidized","ferredoxin","=","nitrate","+","2","reduced","ferredoxin","."),4376346). assertion_content_comment('oboGo_FerredoxinNitritereductaseactivity',s("Catalysis","of","the","reaction",":","NH3","+","2","H2O","+","6","oxidized","ferredoxin","=","nitrite","+","6","reduced","ferredoxin","+","7","H","+"),4334622). assertion_content_comment('oboGo_FerricChelatereductaseactivity',s("Catalysis","of","the","reaction",":","2","Fe2","+","+","NAD","+","=","2","Fe3","+","+","NADH","+","H","+"),4346765). assertion_content_comment('oboGo_FerricEnterobactintransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","ferric-enterobactin","from","one","side","of","a","membrane","to","the","other","."),4289362). assertion_content_comment('oboGo_FerricEnterobactinTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","ferric-enterobactin","(","out",")","=","ADP","+","phosphate","+","ferric-enterobactin","(","in",")"),4289417). assertion_content_comment('oboGo_FerricEnterobactintransport',s("The","directed","movement","of","ferric-enterobactin","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4290075). assertion_content_comment('oboGo_FerricHydroxamatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","ferric-hydroxamate","from","one","side","of","a","membrane","to","the","other","."),4289372). assertion_content_comment('oboGo_FerricHydroxamateTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","ferric-hydroxamate","(","out",")","=","ADP","+","phosphate","+","ferric-hydroxamate","(","in",")"),4289440). assertion_content_comment('oboGo_FerricHydroxamatetransport',s("The","directed","movement","of","ferric-hydroxamate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4290043). assertion_content_comment('oboGo_FerricTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Fe3","+","(","out",")","=","ADP","+","phosphate","+","Fe3","+","(","in",")"),4291358). assertion_content_comment('oboGo_FerricVibriobactintransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","ferric-vibriobactin","ions","from","one","side","of","a","membrane","to","the","other","."),4242027). assertion_content_comment('oboGo_Ferulate5Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","ferulic","acid","+","NADPH","+","H","+","+","O2","=","5-hydroxyferulic","acid","+","H2O","+","NADP","+"),4351303). assertion_content_comment('oboGo_FHADomainMediatedcomplexassembly',s("A","process","of","protein","complex","assembly","in","which","the","arrangement","and","bonding","together","of","the","set","of","components","that","form","the","protein","complex","is","mediated","by","an","FHA","(","forkhead-associated",")","domain","interaction","."),4172079). assertion_content_comment('oboGo_FHL2Crebcomplex',s("A","protein","complex","that","contains","CREB","and","FHL2",",","and","is","involved","in","transcriptional","regulation","."),4348549). assertion_content_comment('oboGo_FHL3Crebcomplex',s("A","protein","complex","that","contains","CREB","and","FHL3",",","and","is","involved","in","transcriptional","regulation","."),4348539). assertion_content_comment('oboGo_FibronectinDependentthymocytemigration',s("The","movement","of","a","thymocyte","through","distinct","intrathymic","niches","(","e.g",".","medulla",",","cortex",")",",","where","it","receives","a","unique","set","of","developmental","cues","required","for","T-cell","development",",","dependent","on","fibronectin","in","the","extracellular","matrix","."),4142758). assertion_content_comment('oboGo_FibronectinTissuetransglutaminasecomplex',s("A","protein","complex","that","consists","of","fibronectin","bound","to","tissue","transglutaminase",",","and","is","involved","in","cell","adhesion","."),4167084). assertion_content_comment('oboGo_FilaminAbinding',s("Interacting","selectively","and","non-covalently","with","filamin-A","."),4319114). assertion_content_comment('oboGo_FilaminBbinding',s("Interacting","selectively","and","non-covalently","with","filamin-B","."),4319127). assertion_content_comment('oboGo_FilaminCbinding',s("Interacting","selectively","and","non-covalently","with","filamin-C",",","a","filamin","isoform","that","contains","an","81","amino","acid","insertion","in","repeat","20",",","not","present","in","filamin-A","or","-B","."),4319140). assertion_content_comment('oboGo_FimbriumSpecificchaperoneactivity',s("OBSOLETE",".","Assists","in","the","correct","assembly","of","fimbria",",","extracellular","organelles","that","are","used","to","attach","a","bacterial","cell","to","a","surface",",","but","is","not","a","component","of","the","fimbrium","when","performing","its","normal","biological","function","."),4292437). assertion_content_comment('oboGo_FirstU12Typespliceosomaltransesterificationactivity',s("OBSOLETE",".","Catalysis","of","the","first","transesterification","reaction","of","U12-type","spliceosomal","mRNA","splicing",".","The","intron","branch","site","adenosine","is","the","nucleophile","attacking","the","5","'","splice","site",",","resulting","in","cleavage","at","this","position",".","In","cis","splicing",",","this","is","the","step","that","forms","a","lariat","structure","of","the","intron","RNA",",","which","is","still","joined","to","the","3","'","exon",".","The","catalytic","site","is","thought","to","be","formed","by","U6atac","snRNA","and/or","U2atac","snRNA",",","and/or","associated","proteins","."),4362935). assertion_content_comment('oboGo_FirstU2Typespliceosomaltransesterificationactivity',s("OBSOLETE",".","Catalysis","of","the","first","transesterification","reaction","of","U2-type","spliceosomal","mRNA","splicing",".","The","intron","branch","site","adenosine","is","the","nucleophile","attacking","the","5","'","splice","site",",","resulting","in","cleavage","at","this","position",".","In","cis","splicing",",","this","is","the","step","that","forms","a","lariat","structure","of","the","intron","RNA",",","which","is","still","joined","to","the","3","'","exon",".","The","catalytic","site","is","thought","to","be","formed","by","U6","and/or","U2","snRNA",",","and/or","associated","proteins","."),4362923). assertion_content_comment('oboGo_FK506SensitivepeptidylProlylcisTransisomerase',s("OBSOLETE",".","Interacts","selectively","with","the","immunosuppressant","FK506",",","and","possesses","peptidyl-prolyl","isomerase","activity","(","catalysis","of","the","reaction",":","peptidoproline","(","omega","=","180",")","=","peptidylproline","(","omega","=","0",")",")"),4306953). assertion_content_comment('oboGo_FlapStructureddnabinding',s("Interacting","selectively","and","non-covalently","with","a","flap","structure","in","DNA",".","A","DNA","flap","structure","is","one","in","which","a","single-stranded","length","of","DNA","or","RNA","protrudes","from","a","double-stranded","DNA","molecule","."),4173168). assertion_content_comment('oboGo_Flavanone4Reductaseactivity',s("Catalysis","of","the","reaction",":","(","2S",")","-flavan-4-ol","+","NADP","+","=","(","2S",")","-flavanone","+","NADPH","."),4375786). assertion_content_comment('oboGo_Flavanone7OBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","a","flavanone","+","UDP-D-glucose","=","a","flavanone","7-O-beta-D-glucoside","+","UDP","."),4366859). assertion_content_comment('oboGo_Flavanone7OGlucoside2OBetaLRhamnosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-L-rhamnose","+","a","flavanone","7-O-glucoside","=","UDP","+","a","flavanone","7-O-","[","beta-L-rhamnosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","]"),4343365). assertion_content_comment('oboGo_FlavinContainingcompoundbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","flavin",",","any","derivative","of","the","dimethylisoalloxazine","(","7",",","8-dimethylbenzo","[","g","]","pteridine-2",",","4","(","3H",",","10H",")","-dione",")","skeleton",",","with","a","substituent","on","the","10","position","."),4158914). assertion_content_comment('oboGo_FlavinContainingcompoundcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","flavin",",","any","derivative","of","the","dimethylisoalloxazine","(","7",",","8-dimethylbenzo","[","g","]","pteridine-2",",","4","(","3H",",","10H",")","-dione",")","skeleton",",","with","a","substituent","on","the","10","position","."),4158965). assertion_content_comment('oboGo_FlavinContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","flavin",",","any","derivative","of","the","dimethylisoalloxazine","(","7",",","8-dimethylbenzo","[","g","]","pteridine-2",",","4","(","3H",",","10H",")","-dione",")","skeleton",",","with","a","substituent","on","the","10","position","."),4158906). assertion_content_comment('oboGo_FlavinContainingelectrontransporter',s("OBSOLETE",".","An","oxidoreductase","which","contains","either","flavin-adenine","dinucleotide","or","flavin","mononucleotide","as","a","prosthetic","group",",","utilizes","either","NADH","or","NADPH","and","transfers","electrons","to","other","electron","transfer","proteins","."),4294510). assertion_content_comment('oboGo_FlavinContainingmonooxygenaseactivity',s("Catalysis","of","the","reaction",":","N",",","N-dimethylaniline","+","NADPH","+","H","+","+","O2","=","N",",","N-dimethylaniline","N-oxide","+","NADP","+","+","H2O","."),4205862). assertion_content_comment('oboGo_FlavinLinkedsulfhydryloxidaseactivity',s("Catalysis","of","the","formation","of","disulfide","bridges","."),4302497). assertion_content_comment('oboGo_Flavone7OBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","5",",","7",",","3","'",",","4","'","-tetrahydroxyflavone","=","UDP","+","7-O-beta-D-glucosyl-5",",","7",",","3","'",",","4","'","-tetrahydroxyflavone","."),4375718). assertion_content_comment('oboGo_Flavonoid35Hydroxylaseactivity',s("Catalysis","of","the","reactions",":","a","flavanone","+","NADPH","+","H","+","+","O2","=","a","3","'","-hydroxyflavanone","+","NADP","+","+","H2O",",","and","a","3","'","-hydroxyflavanone","+","NADPH","+","H","+","+","O2","=","a","3","'",",","5","'","-dihydroxyflavanone","+","NADP","+","+","H2O","."),4342242). assertion_content_comment('oboGo_Flavonoid3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","a","flavonoid","+","NADPH","+","H","+","+","O2","=","3","'","-hydroxyflavonoid","+","NADP","+","+","H2O","."),4301171). assertion_content_comment('oboGo_Flavonol3OArabinosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-arabinose","+","a","flavonol","=","UDP","+","a","flavonol","3-O-D-arabinoside","."),4182702). assertion_content_comment('oboGo_Flavonol_3_O_Beta_GlucosideO_MalonyltransferaseActivity',s("Catalysis","of","the","reaction",":","flavonol","3-O-beta-D-glucoside","+","malonyl-CoA","=","malonyl-flavonol","3-O-beta-D-glucoside","+","CoA","."),4365229). assertion_content_comment('oboGo_Flavonol_3_O_GlucosideGlucosyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","flavonol","3-O-beta-D-glucoside","=","UDP","+","a","flavonol","3-O-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","."),4343332). assertion_content_comment('oboGo_Flavonol_3_O_GlucosideL_RhamnosyltransferaseActivity',s("Catalysis","of","the","reaction",":","flavonol","3-O-D-glucoside","+","UDP-L-rhamnose","=","flavonol","3-O-L-rhamnosylglucoside","+","UDP","."),4367009). assertion_content_comment('oboGo_Flavonol3OGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","flavonol","=","UDP","+","a","flavonol","3-O-D-glucoside","."),4375893). assertion_content_comment('oboGo_Flavonol_3_O_GlycosideGlucosyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","flavonol","3-O-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","=","UDP","+","a","flavonol","3-O-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","."),4343322). assertion_content_comment('oboGo_Flavonol_3_O_GlycosideXylosyltransferaseActivity',s("Catalysis","of","the","reaction",":","flavonol","3-O-glycoside","+","UDP-D-xylose","=","flavonol","3-O-D-xylosylglycoside","+","UDP","."),4367310). assertion_content_comment('oboGo_Flavonol_3_O_TriglucosideO_CoumaroyltransferaseActivity',s("Catalysis","of","the","reaction",":","4-coumaroyl-CoA","+","a","flavonol","3-O-","[","beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","]","=","CoA","+","a","flavonol","3-O-","[","6-","(","4-coumaroyl",")","-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucosyl-","(","1-","&","gt",";","2",")","-beta-D-glucoside","]"),4343043). assertion_content_comment('oboGo_Flavonol3Sulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phospho-5","'","-adenylyl","sulfate","+","quercetin","=","adenosine","3","'",",","5","'","-diphosphate","+","H","(","+",")","+","quercetin","3-sulfate","."),4375919). assertion_content_comment('oboGo_Flavonol7OBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","a","flavonol","=","UDP","+","a","flavonol","7-O-beta-D-glucoside","."),4343354). assertion_content_comment('oboGo_FlocculationViaCellWallProteinCarbohydrateinteraction',s("Mannose-sensitive",",","nonsexual","aggregation","of","cells","mediated","by","protein-carbohydrate","(","flocculin-mannan",")","interaction","present","in","the","cell","wall",".","This","process","is","pH-","and","calcium-dependent","and","reversible",".","An","example","of","this","process","is","found","in","Saccharomyces","cerevisiae","."),4095324). assertion_content_comment('oboGo_Fluoren_9_OlDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","fluoren-9-ol","+","2","NADP","+","=","fluoren-9-one","+","2","NADPH","+","2","H","+"),4277381). assertion_content_comment('oboGo_FMetLeuPhereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","fMet-Leu-Phe","receptor","."),4322716). assertion_content_comment('oboGo_FolicAcidContainingcompoundbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","folic","acid","and","its","derivatives","."),4229933). assertion_content_comment('oboGo_FolicAcidContainingcompoundcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","folic","acid","and","its","derivatives","."),4257658). assertion_content_comment('oboGo_FolicAcidContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","folic","acid-containing","compound",",","i.e",".","any","of","a","group","of","heterocyclic","compounds","based","on","the","pteroic","acid","skeleton","conjugated","with","one","or","more","L-glutamic","acid","or","L-glutamate","units","."),4229895). assertion_content_comment('oboGo_FollicleStimulatinghormoneactivity',s("The","action","characteristic","of","follicle-stimulating","hormone","(","FSH",")",",","a","gonadotrophic","glycoprotein","hormone","secreted",",","in","mammals",",","by","the","anterior","pituitary","gland",".","Upon","receptor","binding",",","FSH","stimulates","growth","of","Graafian","follicles","in","the","ovaries","in","females",",","and","stimulates","the","epithelium","of","the","seminiferous","tubules","to","increase","spermatogenesis","."),4302164). assertion_content_comment('oboGo_FollicleStimulatinghormonecomplex',s("A","gonadotrophic","glycoprotein","hormone","secreted",",","in","mammals",",","by","the","anterior","pituitary","gland",";","consists","of","alpha","and","beta","subunits",",","the","latter","of","which","confers","hormonal","specificity","."),4302021). assertion_content_comment('oboGo_FollicleStimulatinghormonereceptoractivity',s("Combining","with","follicle-stimulating","hormone","to","initiate","a","change","in","cell","activity","."),4198121). assertion_content_comment('oboGo_FollicleStimulatinghormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","follicle-stimulating","hormone","receptor","."),4322673). assertion_content_comment('oboGo_FollicleStimulatinghormonesecretion',s("The","regulated","release","of","follicle-stimulating","hormone",",","a","gonadotropic","glycoprotein","hormone","secreted","by","the","anterior","pituitary","."),4099683). assertion_content_comment('oboGo_FollicleStimulatinghormonesignalingpathway',s("The","series","of","molecular","signals","mediated","by","follicle-stimulating","hormone","."),4078401). assertion_content_comment('oboGo_ForebrainMidbrainboundaryformation',s("The","process","whose","specific","outcome","is","the","creation","of","the","forebrain-midbrain","boundary","."),4048585). assertion_content_comment('oboGo_FormateCAcetyltransferaseActivatingenzymeactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","dihydroflavodoxin","+","[","formate","C-acetyltransferase","]","-glycine","=","5","'","-deoxyadenosine","+","L-methionine","+","flavodoxin","semiquinone","+","[","formate","C-acetyltransferase","]","-glycin-2-yl","radical","."),4318321). assertion_content_comment('oboGo_FormateCAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","formate","=","CoA","+","pyruvate","."),4249553). assertion_content_comment('oboGo_FormateDehydrogenaseCytochrome_C_553Activity',s("Catalysis","of","the","reaction",":","ferricytochrome","C-553","+","formate","=","ferrocytochrome","C-553","+","CO2","."),4365828). assertion_content_comment('oboGo_FormateDihydrofolateligaseactivity',s("Catalysis","of","the","reaction",":","7",",","8-dihydrofolate","+","ATP","+","formate","=","10-formyldihydrofolate","+","ADP","+","H","(","+",")","+","phosphate","."),4375845). assertion_content_comment('oboGo_FormateTetrahydrofolateligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","formate","+","tetrahydrofolate","=","ADP","+","phosphate","+","10-formyltetrahydrofolate","."),4208533). assertion_content_comment('oboGo_ForminNucleatedactincableassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","set","of","components","to","form","a","formin-nucleated","actin","cable",".","A","formin-nucleated","actin","cable","is","an","actin","filament","bundle","that","consists","of","short","filaments","organized","into","bundles","of","uniform","polarity",",","and","is","nucleated","by","formins","."),4150617). assertion_content_comment('oboGo_ForminNucleatedactincable',s("An","actin","filament","bundle","that","consists","of","short","filaments","organized","into","bundles","of","uniform","polarity",",","and","is","nucleated","by","formins",".","In","fungal","cells",",","myosin","motors","transport","cargo","along","actin","cables","toward","sites","of","polarized","cell","growth",";","actin","cables","may","play","a","similar","role","in","pollen","tube","growth","."),4176831). assertion_content_comment('oboGo_FormylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","formyl-CoA","+","H","(","2",")","O","=","CoA","+","formate","+","H","(","+",")"),4377904). assertion_content_comment('oboGo_FormylCoatransferaseactivity',s("Catalysis","of","the","reaction",":","formyl-CoA","+","oxalate","=","formate","+","oxalyl-CoA","."),4341651). assertion_content_comment('oboGo_FormylmethanofuranTetrahydromethanopterinnFormyltransferaseactivity',s("Catalysis","of","the","reaction",":","5",",","6",",","7",",","8-tetrahydromethanopterin","+","N-formylmethanofuran","+","H","(","+",")","=","N","(","5",")","-formyl-5",",","6",",","7",",","8-tetrahydromethanopterin","+","methanofuran","."),4311909). assertion_content_comment('oboGo_Fosfomycin2Glutathioneligaseactivity',s("Catalysis","of","the","reaction",":","hydrogen","(","2R",",","3S",")","-3-methyloxiran-2-ylphosphonic","acid","+","glutathione","=","hydrogen","(","1R",",","2R",")","-1-glutathio-2-hydroxypropylphosphonic","acid","."),4349830). assertion_content_comment('oboGo_Fosfomycin2LCysteineligaseactivity',s("Catalysis","of","the","reaction",":","hydrogen","(","2R",",","3S",")","-3-methyloxiran-2-ylphosphonic","acid","+","L-cysteine","=","hydrogen","(","1R",",","2R",")","-1-","L-cysteine-2-hydroxypropylphosphonic","acid","."),4349821). assertion_content_comment('oboGo_FourWayjunctiondnabinding',s("Interacting","selectively","and","non-covalently","with","DNA","containing","four-way","junctions",",","also","known","as","Holliday","junctions",",","a","structure","where","two","DNA","double","strands","are","held","together","by","reciprocal","exchange","of","two","of","the","four","strands",",","one","strand","each","from","the","two","original","helices","."),4362754). assertion_content_comment('oboGo_FourWayjunctionhelicaseactivity',s("Catalysis","of","the","unwinding","of","the","DNA","helix","of","DNA","containing","four-way","junctions",",","including","Holliday","junctions","."),4260044). assertion_content_comment('oboGo_FreeLAminoacidracemization',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4282060). assertion_content_comment('oboGo_Frizzled_2Binding',s("Interacting","selectively","and","non-covalently","with","frizzled-2","(","fz2",")"),4214823). assertion_content_comment('oboGo_Frizzled_2ReceptorActivity',s("OBSOLETE",".","Combining","with","to","a","member","of","the","Wnt-family","of","signaling","molecules","to","initiate","a","change","in","cell","activity","."),4198481). assertion_content_comment('oboGo_FructanBeta_21_FructosidaseActivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","2",",","1-linked","beta-D-fructofuranose","residues","in","fructans","."),4344393). assertion_content_comment('oboGo_FructanBeta_26_FructosidaseActivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","2",",","6-linked","beta-D-fructofuranose","residues","in","fructans","."),4344381). assertion_content_comment('oboGo_FructanBetaFructosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","2",",","1-","and","2",",","6-linked","beta-D-fructofuranose","residues","in","fructans","."),4285398). assertion_content_comment('oboGo_Fructosamine_3_KinaseActivity',s("Catalysis","of","the","phosphorylation","of","fructosamine","to","form","fructosamine-3-kinase","."),4309438). assertion_content_comment('oboGo_Fructose16Bisphosphate1Phosphataseactivity',s("Catalysis","of","the","reaction",":","D-fructose","1",",","6-bisphosphate","+","H2O","=","D-fructose","6-phosphate","+","phosphate","."),4313789). assertion_content_comment('oboGo_Fructose16Bisphosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","fructose","1",",","6-bisphosphate",",","also","known","as","FBP",".","The","D","enantiomer","is","a","metabolic","intermediate","in","glycolysis","and","gluconeogenesis","."),4116401). assertion_content_comment('oboGo_Fructose_26_Bisphosphate2_PhosphataseActivity',s("Catalysis","of","the","reaction",":","D-fructose","2",",","6-bisphosphate","+","H2O","=","D-fructose-6-phosphate","+","phosphate","."),4208413). assertion_content_comment('oboGo_Fructose_26_Bisphosphate6_PhosphataseActivity',s("Catalysis","of","the","reaction",":","beta-D-fructose","2",",","6-bisphosphate","+","H","(","2",")","O","=","beta-D-fructofuranose","2-phosphate","+","phosphate","."),4368672). assertion_content_comment('oboGo_Fructose26Bisphosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","fructose","2",",","6-bisphosphate",".","The","D","enantiomer","is","an","important","regulator","of","the","glycolytic","and","gluconeogenic","pathways",".","It","inhibits","fructose","1",",","6-bisphosphatase","and","activates","phosphofructokinase","."),4225105). assertion_content_comment('oboGo_Fructose5Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-fructose","+","A","=","5-dehydro-D-fructose","+","AH","(","2",")"),4377942). assertion_content_comment('oboGo_Fructose5Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","D-fructose","+","NADP","+","=","5-dehydro-D-fructose","+","NADPH","."),4377926). assertion_content_comment('oboGo_Fructose6Phosphatealdolaseactivity',s("Catalysis","of","the","reaction",":","D-fructose-6-phosphate","=","dihydroxyacetone","+","D-glyceraldehyde-3-phosphate","."),4073964). assertion_content_comment('oboGo_Fructose_6_PhosphateBinding',s("Interacting","selectively","and","non-covalently","with","fructose","6-phosphate","."),4180274). assertion_content_comment('oboGo_Fructose6Phosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","fructose","6-phosphate",",","also","known","as","F6P",".","The","D-enantiomer","is","an","important","intermediate","in","glycolysis",",","gluconeogenesis",",","and","fructose","metabolism","."),4225130). assertion_content_comment('oboGo_Fructose_6_PhosphatePhosphoketolaseActivity',s("Catalysis","of","the","reaction",":","D-fructose","6-phosphate","+","phosphate","=","acetyl","phosphate","+","D-erythrose","4-phosphate","+","H2O","."),4377956). assertion_content_comment('oboGo_FructoseBisphosphatealdolaseactivity',s("Catalysis","of","the","reaction",":","D-fructose","1",",","6-bisphosphate","=","glycerone","phosphate","+","D-glyceraldehyde-3-phosphate","."),4208426). assertion_content_comment('oboGo_FructosylAminoacidoxidaseactivity',s("Catalysis","of","the","reaction",":","fructosyl-amino","acid","+","O2","=","corresponding","amino","acid","+","glucosone","+","H2O2","."),4280501). assertion_content_comment('oboGo_Fucose_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","beta-L-fucose","1-phosphate","+","GTP","=","diphosphate","+","GDP-L-fucose","."),4368108). assertion_content_comment('oboGo_FucosterolEpoxidelyaseactivity',s("Catalysis","of","the","reaction",":","(","24R",",","24","'","R",")","-fucosterol","epoxide","=","acetaldehyde","+","desmosterol","."),4377967). assertion_content_comment('oboGo_Fucosylgalactoside3AlphaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","glycoprotein-alpha-L-fucosyl-","(","1",",","2",")","-D-galactose","=","UDP","+","glycoprotein-alpha-D-galactosyl-","(","1",",","3",")","-","(","alpha-L-fucosyl-","(","1",",","2",")",")","-D-galactose","."),4208208). assertion_content_comment('oboGo_FungalTypecellwall13AlphaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1",",","3-alpha-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-alpha-D-glucosidic","bonds",",","found","in","fungal-type","cell","walls",",","including","those","of","ascospores","."),4130641). assertion_content_comment('oboGo_FungalTypecellwall13AlphaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","alpha-1",",","3","glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-alpha-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4130636). assertion_content_comment('oboGo_FungalTypecellwall13BetaDGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1",",","3-beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4111548). assertion_content_comment('oboGo_FungalTypecellwall13BetaDGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","1",",","3-beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","1",",","3-beta-D-glucosidic","bonds",",","found","in","the","walls","of","ascospores","."),4111458). assertion_content_comment('oboGo_FungalTypecellwallassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","set","of","components","to","form","a","fungal-type","cell","wall","."),4046990). assertion_content_comment('oboGo_FungalTypecellwallbetaGlucanbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","fungal","cells","."),4111488). assertion_content_comment('oboGo_FungalTypecellwallbetaGlucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","beta-glucans",",","compounds","composed","of","glucose","residues","linked","by","beta-D-glucosidic","bonds",",","found","in","the","walls","of","fungal","cells","."),4074639). assertion_content_comment('oboGo_FungalTypecellwallbiogenesis',s("A","cellular","process","that","results","in","the","biosynthesis","of","constituent","macromolecules",",","assembly",",","and","arrangement","of","constituent","parts","of","a","fungal-type","cell","wall",".","The","fungal-type","cell","wall","contains","beta-glucan","and","may","contain","chitin","."),4046866). assertion_content_comment('oboGo_FungalTypecellwallchitinbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","cell","wall","chitin",",","a","linear","polysaccharide","consisting","of","P-1",",","4-linked","N-acetyl-D-glucosamine","residues",",","found","in","the","walls","of","fungal","cells","."),4075436). assertion_content_comment('oboGo_FungalTypecellwalldisassembly',s("A","cellular","process","that","results","in","the","breakdown","of","a","fungal-type","cell","wall","."),4075630). assertion_content_comment('oboGo_FungalTypecellwallorganizationorbiogenesis',s("A","process","that","results","in","the","biosynthesis","of","constituent","macromolecules",",","assembly",",","arrangement","of","constituent","parts",",","or","disassembly","of","a","fungal-type","cell","wall","."),4046863). assertion_content_comment('oboGo_FungalTypecellwallorganization',s("A","process","that","is","carried","out","at","the","cellular","level","which","results","in","the","assembly",",","arrangement","of","constituent","parts",",","or","disassembly","of","the","fungal-type","cell","wall","."),4075622). assertion_content_comment('oboGo_FungalTypecellwallpolysaccharidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","the","polysaccharides","which","make","up","the","fungal-type","cell","wall","."),4075430). assertion_content_comment('oboGo_FungalTypecellwallpolysaccharidemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","the","polysaccharides","which","make","up","the","fungal-type","cell","wall","."),4074636). assertion_content_comment('oboGo_FungalTypecellwall',s("A","rigid","yet","dynamic","structure","surrounding","the","plasma","membrane","that","affords","protection","from","stresses","and","contributes","to","cell","morphogenesis",",","consisting","of","extensively","cross-linked","glycoproteins","and","carbohydrates",".","The","glycoproteins","may","be","modified","with","N-","or","O-linked","carbohydrates",",","or","glycosylphosphatidylinositol","(","GPI",")","anchors",";","the","polysaccharides","are","primarily","branched","glucans",",","including","beta-linked","and","alpha-linked","glucans",",","and","may","also","include","chitin","and","other","carbohydrate","polymers",",","but","not","cellulose","or","pectin",".","Enzymes","involved","in","cell","wall","biosynthesis","are","also","found","in","the","cell","wall",".","Note","that","some","forms","of","fungi","develop","a","capsule","outside","of","the","cell","wall","under","certain","circumstances",";","this","is","considered","a","separate","structure","."),4006884). assertion_content_comment('oboGo_FungalTypevacuolelumen',s("The","volume","enclosed","within","the","vacuolar","membrane","of","a","vacuole",",","the","shape","of","which","correlates","with","cell","cycle","phase",".","An","example","of","this","structure","is","found","in","Saccharomyces","cerevisiae","."),3975062). assertion_content_comment('oboGo_FungalTypevacuolemembrane',s("The","lipid","bilayer","surrounding","a","vacuole",",","the","shape","of","which","correlates","with","cell","cycle","phase",".","The","membrane","separates","its","contents","from","the","cytoplasm","of","the","cell",".","An","example","of","this","structure","is","found","in","Saccharomyces","cerevisiae","."),3975073). assertion_content_comment('oboGo_FungalTypevacuole',s("A","vacuole","that","has","both","lytic","and","storage","functions",".","The","fungal","vacuole","is","a","large",",","membrane-bounded","organelle","that","functions","as","a","reservoir","for","the","storage","of","small","molecules","(","including","polyphosphate",",","amino","acids",",","several","divalent","cations","(","e.g",".","calcium",")",",","other","ions",",","and","other","small","molecules",")","as","well","as","being","the","primary","compartment","for","degradation",".","It","is","an","acidic","compartment",",","containing","an","ensemble","of","acid","hydrolases",".","At","least","in","S",".","cerevisiae",",","there","are","indications","that","the","morphology","of","the","vacuole","is","variable","and","correlated","with","the","cell","cycle",",","with","logarithmically","growing","cells","having","a","multilobed",",","reticulated","vacuole",",","while","stationary","phase","cells","contain","a","single","large","structure","."),3975041). assertion_content_comment('oboGo_FusarinineCornithinesteraseactivity',s("Catalysis","of","the","reaction",":","N5-acyl-L-ornithine","ester","+","H2O","=","N5-acyl-L-ornithine","+","an","alcohol","."),4377988). assertion_content_comment('oboGo_GAACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GAA","codon","."),4339516). assertion_content_comment('oboGo_GABAAreceptoractivity',s("Combining","with","the","amino","acid","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")","to","initiate","a","change","in","cell","activity",".","GABA-A","receptors","function","as","chloride","channels","."),4200200). assertion_content_comment('oboGo_GABABreceptoractivity',s("Combining","with","the","amino","acid","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")","to","initiate","a","change","in","cell","activity",".","GABA-B","receptors","are","G-protein","coupled","receptors","."),4198158). assertion_content_comment('oboGo_GABAGatedchlorideionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","GABA","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4333099). assertion_content_comment('oboGo_GACCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GAC","codon","."),4339527). assertion_content_comment('oboGo_GAGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GAG","codon","."),4339655). assertion_content_comment('oboGo_Galactan13BetaGalactosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal",",","non-reducing","beta-D-galactose","residues","in","(","1-","&","gt",";","3",")","-beta-D-galactopyranans","."),4344410). assertion_content_comment('oboGo_GalactarateOHydroxycinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","feruloyl-CoA","+","galactarate","=","2-","(","E",")","-O-feruloyl-D-galactarate","+","CoA","."),4365192). assertion_content_comment('oboGo_GalactinolRaffinosegalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","raffinose","+","1-alpha-D-galactosyl-myo-inositol","=","stachyose","+","myo-inositol","."),4367131). assertion_content_comment('oboGo_GalactinolSucrosegalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","sucrose","+","1-alpha-D-galactosyl-myo-inositol","=","raffinose","+","myo-inositol","."),4367486). assertion_content_comment('oboGo_Galactitol_1_Phosphate5_DehydrogenaseActivity',s("Catalysis","of","the","reaction",":","galactitol-1-phosphate","+","NAD","+","=","L-tagatose","6-phosphate","+","NADH","+","H","+"),4249615). assertion_content_comment('oboGo_Galactitol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","galactitol","+","NAD","(","+",")","=","D-tagatose","+","H","(","+",")","+","NADH","."),4374462). assertion_content_comment('oboGo_Galactogen6BetaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","galactogen","+","UDP-galactose","=","1",",","6-beta-D-galctosylgalactogen","+","UDP","."),4367258). assertion_content_comment('oboGo_GalactolipidOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","mono-beta-D-galactosyldiacylglycerol","=","acylmono-beta-D-galactosyl-diacylglycerol","+","mono-beta-D-galactosylacylglycerol","."),4378000). assertion_content_comment('oboGo_Galactosamine_6_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-galactosamine","6-phosphate","+","H2O","=","D-tagatose","6-phosphate","+","NH3","."),4326838). assertion_content_comment('oboGo_Galactose1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-galactose","+","NAD","+","=","D-galactono-1",",","4-lactone","+","NADH","+","H","+"),4237544). assertion_content_comment('oboGo_Galactose1Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","D-galactose","+","NADP","+","=","D-galactonolactone","+","NADPH","."),4377893). assertion_content_comment('oboGo_Galactose_1_PhosphateGuanylyltransferaseGDPActivity',s("Catalysis","of","the","reaction",":","GDP","+","L-galactose","1-phosphate","=","phosphate","+","GDP-galactose","."),4332891). assertion_content_comment('oboGo_Galactose_1_PhosphatePhosphataseActivity',s("Catalysis","of","the","reaction",":","galactose-1-phosphate","+","H2O","=","galactose","+","phosphate","."),4176033). assertion_content_comment('oboGo_Galactose_1_PhosphateThymidylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-galactose","1-phosphate","+","dTTP","=","diphosphate","+","dTDP-D-galactose","."),4368092). assertion_content_comment('oboGo_Galactose3OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyllactosamine","+","3","'","-phosphoadenosine","5","'","-phosphosulfate","=","3-sulfo-N-acetyllactosamine","+","adenosine","3","'",",","5","'","-bisphosphate",".","N-acetyllactosamine","residues","are","found","in","a","number","of","different","carbohydrate","types",".","N-acetyllactosamine","can","also","be","written","as","Gal-beta-","(","1",",","4",")","-GlcNAc","."),4277159). assertion_content_comment('oboGo_Galactose_6_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-galactose","6-phosphate","=","D-tagatose","6-phosphate","."),4270274). assertion_content_comment('oboGo_Galactose_6_SulfurylaseActivity',s("Catalysis","of","the","elimination","of","sulfate","from","the","D-galactose","6-sulfate","residues","of","porphyran",",","producing","3",",","6-anhydrogalactose","residues","."),4343919). assertion_content_comment('oboGo_GalactoseCatabolicProcessViaDGalactonate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","galactose",",","via","the","intermediate","D-galactonate","."),4339726). assertion_content_comment('oboGo_GalactoseCatabolicProcessViaUDPGalactose',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","galactose",",","via","the","intermediate","UDP-galactose","."),4339713). assertion_content_comment('oboGo_Galactoside2AlphaLFucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","GDP-L-fucose","+","beta-D-galactosyl-R","=","GDP","+","alpha-L-fucosyl-","(","1",",","2",")","-beta-D-galactosyl-R","."),4246445). assertion_content_comment('oboGo_Galactoside6LFucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","L-fucosyl","group","from","GDP-beta-L-fucose","to","a","galactoside","acceptor","molecule",",","usually","an","N-glycan",",","to","form","an","alpha","(","1",",","6",")","-fucosylated","galactoside","."),4356033). assertion_content_comment('oboGo_GalactosideOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","a","beta-D-galactoside","=","CoA","+","a","6-acetyl-beta-D-galactoside","."),4249707). assertion_content_comment('oboGo_GalactosylacylglycerolOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","sn-3-D-galactosyl-sn-2-acylglycerol","+","acyl-","[","acyl-carrier","protein","]","=","D-galactosyldiacylglycerol","+","[","acyl-carrier","protein","]"),4366387). assertion_content_comment('oboGo_GalactosylBeta_13N_AcetylgalactosamineBeta_13_GlucuronosyltransferaseActivity',s("Catalysis","of","the","transfer",",","in","a","beta","1",",","3","linkage",",","of","D-glucuronic","acid","(","GlcUA",")","from","UDP-GlcUA","to","the","disaccharide","galactosyl","beta-1",",","3","N-acetylgalactosamine",",","a","common","component","of","glycoproteins","and","glycolipids","."),4361737). assertion_content_comment('oboGo_GalactosyldiacylglycerolAlpha_23_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","1",",","2-diacyl-3-beta-D-galactosyl-sn-glycerol","+","CMP-N-acetyl-beta-neuraminate","=","1",",","2-diacyl-3-","[","3-","(","alpha-D-N-acetylneuraminyl",")","-beta-D-galactosyl","]","-sn-glycerol","+","CMP","+","H","(","+",")"),4367410). assertion_content_comment('oboGo_GalactosylgalactosylglucosylceramideBetaDAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-galactosamine","+","alpha-D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-glucosylceramide","=","UDP","+","beta-N-acetyl-D-galactosaminyl-","(","1-","&","gt",";","3",")","-alpha-D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-glucosylceramide","."),4367465). assertion_content_comment('oboGo_Galactosylgalactosylxylosylprotein3BetaGlucuronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucuronate","+","3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein","=","UDP","+","3-beta-D-glucuronosyl-3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein","."),4296812). assertion_content_comment('oboGo_Galactosyl_N_Acetylglucosaminylgalactosylglucosyl_CeramideBeta_16_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-D-glucosaminyl-1",",","6-beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosyceramide","+","UDP","."),4366983). assertion_content_comment('oboGo_Galactosylxylosylprotein3BetaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","4-beta-D-galactosyl-O-beta-D-xylosylprotein","+","UDP-galactose","=","3-beta-D-galactosyl-4-beta-D-galactosyl-O-beta-D-xylosylprotein","+","UDP","."),4366590). assertion_content_comment('oboGo_Galacturan14AlphaGalacturonidaseactivity',s("Catalysis","of","the","reaction",":","1",",","4-alpha-D-galacturonide","(","n",")","+","H2O","=","1",",","4-alpha-D-galacturonide","(","n-1",")","+","D-galacturonate","."),4377876). assertion_content_comment('oboGo_Gallate1BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","gallate","+","UDP-D-glucose","=","1-O-galloyl-beta-D-glucose","+","UDP","."),4378145). assertion_content_comment('oboGo_GallateCatabolicProcessVia2_Pyrone_46_Dicarboxylate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","gallate",",","the","anion","of","gallic","acid",",","via","the","intermediate","2-pyrone-4",",","6-dicarboxylate","."),4239287). assertion_content_comment('oboGo_GallateCatabolicProcessVia4_Carboxy_2_Hydroxhexa_23_Dienedioate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","gallate",",","the","anion","of","gallic","acid",",","via","the","intermediate","4-carboxy-2-hydroxhexa-2",",","3-dienedioate","."),4239273). assertion_content_comment('oboGo_GametophyticSelfIncompatibility',s("OBSOLETE",".","A","mechanism","that","functions","to","prevent","self-fertilization","in","flowering","plants","that","is","determined","by","the","diploid","genotype","of","the","parent","plant",".","In","sporophytic","incompatibility","the","pollen","does","not","germinate",",","consequently","fertilization","does","not","take","place","."),4262218). assertion_content_comment('oboGo_Gamma_123456_HexachlorocyclohexaneMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","gamma-1",",","2",",","3",",","4",",","5",",","6-hexachlorocyclohexane","(","also","known","as","Lindane",")",",","the","most","common","form","of","hexachlorohexane",",","a","halogenated","organic","insecticide","that","has","been","used","worldwide","for","agriculture","and","public","health","."),4272167). assertion_content_comment('oboGo_GammaAminobutyricacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")",",","an","amino","acid","which","acts","as","a","neurotransmitter","in","some","organisms","."),4258687). assertion_content_comment('oboGo_GammaAminobutyricacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")",",","an","amino","acid","which","acts","as","a","neurotransmitter","in","some","organisms","."),4259078). assertion_content_comment('oboGo_GammaAminobutyricacid_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","gamma-aminobutyric","acid","(","out",")","+","H","+","(","out",")","=","gamma-aminobutyric","acid","(","in",")","+","H","+","(","in",")"),4292274). assertion_content_comment('oboGo_GammaAminobutyricacidimport',s("The","directed","movement","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")","into","a","cell","or","organelle","."),4120550). assertion_content_comment('oboGo_GammaAminobutyricacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")",",","an","amino","acid","which","acts","as","a","neurotransmitter","in","some","organisms","."),4258678). assertion_content_comment('oboGo_GammaAminobutyricacidsecretion',s("The","regulated","release","of","gamma-aminobutyric","acid","by","a","cell","or","group","of","cells",".","The","gamma-aminobutyric","acid","is","the","principal","inhibitory","neurotransmitter","in","the","brain","but","is","also","found","in","several","extraneural","tissues","."),4039332). assertion_content_comment('oboGo_GammaAminobutyricacidsignalingpathway',s("The","series","of","molecular","signals","generated","by","the","binding","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")",",","an","amino","acid","which","acts","as","a","neurotransmitter","in","some","organisms",",","to","a","cell","surface","receptor","."),4235638). assertion_content_comment('oboGo_GammaAminobutyricacid_Sodiumsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","gamma-aminobutyric","acid","(","out",")","+","Na","+","(","out",")","=","gamma-aminobutyric","acid","(","in",")","+","Na","+","(","in",")"),4216266). assertion_content_comment('oboGo_GammaAminobutyricacidtransport',s("The","directed","movement","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")",",","an","amino","acid","which","acts","as","a","neurotransmitter","in","some","organisms",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4039325). assertion_content_comment('oboGo_GammaAminobutyricaciduptakeinvolvedinsynaptictransmission',s("The","uptake","of","gamma-aminobutyric","acid","(","GABA",",","4-aminobutyrate",")","by","neurons","or","glial","cells",".","This","process","leads","to","inactivation","and","recycling","of","neurotransmitters","."),4120556). assertion_content_comment('oboGo_GammaAminovinylacetatedeaminaseactivity',s("Catalysis","of","the","reaction",":","gamma-aminovinylacetate","+","H2O","=","succinic","semialdehyde","+","NH3","."),4351093). assertion_content_comment('oboGo_GammaButyrobetainedioxygenaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","4-","(","trimethylammonio",")","butanoate","+","O","(","2",")","=","carnitine","+","CO","(","2",")","+","succinate","."),4255267). assertion_content_comment('oboGo_GammaCateninbinding',s("Interacting","selectively","and","non-covalently","with","the","gamma","subunit","of","the","catenin","complex","."),4298686). assertion_content_comment('oboGo_GammaCateninTcf7l2complex',s("A","protein","complex","that","contains","gamma-catenin","and","TCF7L2","(","TCF4",")",",","binds","to","the","TCF","DNA","motif","within","a","promoter","element",",","and","is","involved","in","the","regulation","of","WNT","target","gene","transcription","."),4172371). assertion_content_comment('oboGo_GammaDeltaintraepithelialtcelldifferentiation',s("The","process","in","which","a","precursor","cell","type","acquires","the","specialized","features","of","a","gamma-delta","intraepithelial","T","cell",".","Intraepithelial","T","cells","are","found","among","epithelial","cells","in","mucosal","areas","and","have","distinct","phenotypes","and","developmental","pathways","."),4380376). assertion_content_comment('oboGo_GammaDeltatcellactivationinvolvedinimmuneresponse',s("The","change","in","morphology","and","behavior","of","a","gamma-delta","T","cell","resulting","from","exposure","to","a","mitogen",",","cytokine",",","chemokine",",","cellular","ligand",",","or","an","antigen","for","which","it","is","specific",",","leading","to","the","initiation","or","perpetuation","of","an","immune","response","."),4378298). assertion_content_comment('oboGo_GammaDeltatcellactivation',s("The","change","in","morphology","and","behavior","of","a","gamma-delta","T","cell","resulting","from","exposure","to","a","mitogen",",","cytokine",",","chemokine",",","cellular","ligand",",","or","an","antigen","for","which","it","is","specific","."),3994090). assertion_content_comment('oboGo_GammaDeltatcelldifferentiationinvolvedinimmuneresponse',s("The","process","in","which","an","antigenically","naive","gamma-delta","T","cell","acquires","the","specialized","features","of","an","effector",",","regulatory",",","or","memory","T","cell","and","contributes","to","an","immune","response",".","Effector","T","cells","include","cells","which","provide","T","cell","help","or","exhibit","cytotoxicity","towards","other","cells","."),4380422). assertion_content_comment('oboGo_GammaDeltatcelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","hemopoietic","cell","acquires","specialized","features","of","a","gamma-delta","T","cell",".","A","gamma-delta","T","cell","is","a","T","cell","that","expresses","a","gamma-delta","T","cell","receptor","complex","."),3994095). assertion_content_comment('oboGo_GammaDeltatcelllineagecommitment',s("The","process","in","which","a","pro-T","cell","becomes","committed","to","becoming","a","gamma-delta","T","cell","."),3994109). assertion_content_comment('oboGo_GammaDeltatcellproliferationinvolvedinimmuneresponse',s("The","expansion","of","a","gamma-delta","T","cell","population","by","cell","division","as","part","of","an","immune","response","."),4380510). assertion_content_comment('oboGo_GammaDeltatcellproliferation',s("The","expansion","of","a","gamma-delta","T","cell","population","by","cell","division","."),4098946). assertion_content_comment('oboGo_GammaDeltatcellreceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4306554). assertion_content_comment('oboGo_GammaDeltatcellreceptorcomplex',s("A","T","cell","receptor","complex","in","which","the","TCR","heterodimer","comprises","gamma","and","delta","chains",",","associated","with","the","CD3","complex",";","recognizes","antigen","directly",",","without","a","requirement","for","processing","and","presentation","by","an","MHC","protein","."),4313752). assertion_content_comment('oboGo_GammaGlutamylcarboxylaseactivity',s("Catalysis","of","the","reaction",":","peptidyl-glutamate","+","reduced","vitamin","K","+","CO2","+","O2","=","peptidyl-gamma-carboxyglutamate","+","vitamin","K","epoxide","."),4254311). assertion_content_comment('oboGo_GammaGlutamylcyclotransferaseactivity',s("Catalysis","of","the","reaction",":","(","5-L-glutamyl",")","-L-amino","acid","=","5-oxoproline","+","L-amino","acid","."),4188768). assertion_content_comment('oboGo_GammaGlutamylGammaAminobutyratehydrolaseactivity',s("Catalysis","of","the","reaction",":","4-","(","L-gamma-glutamylamino",")","butanoate","+","H","(","2",")","O","=","4-aminobutanoate","+","L-glutamate","."),4345109). assertion_content_comment('oboGo_GammaGlutamylhistaminesynthaseactivity',s("Catalysis","of","the","reaction",":","histamine","+","L-glutamate","+","ATP","=","N","(","alpha",")","-gamma-L-glutamylhistamine","+","products","of","ATP","breakdown","."),4378100). assertion_content_comment('oboGo_GammaGlutamylhydrolaseactivity',s("OBSOLETE",".","Catalysis","of","the","cleavage","of","a","gamma-glutamyl","bond","to","release","an","unsubstituted","C-terminal","amino","acid","."),4254078). assertion_content_comment('oboGo_GammaGlutamylPeptidaseactivity',s("Catalysis","of","the","cleavage","of","a","gamma-linked","glutamate","bond","."),4349192). assertion_content_comment('oboGo_GammaGlutamyltransferaseactivity',s("Catalysis","of","the","reaction",":","(","5-L-glutamyl",")","-peptide","+","an","amino","acid","=","peptide","+","5-L-glutamyl-amino","acid","."),4188530). assertion_content_comment('oboGo_GammaGuanidinobutyraldehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","4-guanidinobutanal","+","H","(","2",")","O","+","NAD","(","+",")","=","4-guanidinobutanoate","+","2","H","(","+",")","+","NADH","."),4366074). assertion_content_comment('oboGo_GammaHexachlorocyclohexanedehydrochlorinaseactivity',s("Catalysis","of","the","reaction",":","gamma-hexachlorocyclohexane","+","HCl","=","1",",","3","(","R",")",",","4","(","S",")",",","5","(","S",")",",","6","(","R",")","-pentachlorocyclohexene","."),4273484). assertion_content_comment('oboGo_GammaNFormylaminovinylacetaldehydedehydrogenaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","gamma-N-formylaminovinylacetaldehyde","+","H2O","=","gamma-N-formylaminovinylacetate","+","2","H","+","+","2","e-","."),4351115). assertion_content_comment('oboGo_GammaNFormylaminovinylacetatehydrolaseactivity',s("Catalysis","of","the","reaction",":","gamma-N-formylaminovinylacetate","+","H2O","=","gamma-aminovinylacetate","+","HCOOH","."),4351124). assertion_content_comment('oboGo_GammaReninactivity',s("OBSOLETE",".","Catalysis","of","the","cleavage","of","the","Leu-Leu","bond","in","synthetic","tetradecapeptide","renin","substrate",",","producing","angiotensin","I",",","but","not","active","on","natural","angiotensinogen",".","Also","hydrolyzes","BZ-Arg-para-nitroanilide","."),4210283). assertion_content_comment('oboGo_GammaSecretasecomplex',s("A","protein","complex","that","has","aspartic-type","endopeptidase","activity",",","and","contains","a","catalytic","subunit",",","presenilin","(","PS",")",",","that","is","a","prototypical","member","of","the","GxGD-type","aspartyl","peptidases",".","The","complex","also","contains","additional","subunits",",","including","nicastrin",",","APH-1",",","PEN-2",",","and","a","regulatory","subunit",",","CD147",".","Gamma-secretase","cleaves","several","transmembrane","proteins","including","the","cell","surface","receptor","Notch","and","the","beta-amyloid","precursor","protein","."),4176339). assertion_content_comment('oboGo_GammaSecretaseDelta1complex',s("A","protein","complex","that","is","formed","by","the","association","of","the","Notch","ligand","Delta1","with","the","gamma-secretase","complex","."),4176307). assertion_content_comment('oboGo_GammaTocopherolcyclaseactivity',s("Catalysis","of","the","reaction",":","2",",","3-dimethyl-6-phytyl-1",",","4-benzoquinone","=","gamma-tocopherol","."),4190980). assertion_content_comment('oboGo_GammaTubulinbinding',s("Interacting","selectively","and","non-covalently","with","the","microtubule","constituent","protein","gamma-tubulin","."),4318058). assertion_content_comment('oboGo_GammaTubulincomplexlocalization',s("Any","process","in","which","a","gamma-tubulin","complex","is","transported","to",",","or","maintained","in",",","a","specific","location","."),4341157). assertion_content_comment('oboGo_GammaTubulincomplex',s("A","multiprotein","complex","composed","of","gamma-tubulin","and","other","non-tubulin","proteins",".","Gamma-tubulin","complexes","are","localized","to","microtubule","organizing","centers",",","and","play","an","important","role","in","the","nucleation","of","microtubules",".","The","number","and","complexity","of","non-tubulin","proteins","associated","with","these","complexes","varies","between","species","."),3979359). assertion_content_comment('oboGo_GammaTubulinlargecomplexequatorialmicrotubuleorganizingcenter',s("A","complex","of","gamma","tubulin","and","associated","proteins","thought","to","be","formed","by","multimerization","of","gamma-tubulin","small","complexes","located","at","equatorial","microtubule","organizing","centers","."),4107900). assertion_content_comment('oboGo_GammaTubulinlargecomplexinterphasemicrotubuleorganizingcenter',s("A","complex","of","gamma","tubulin","and","associated","proteins","thought","to","be","formed","by","multimerization","of","gamma-tubulin","small","complexes","located","at","interphase","microtubule","organizing","centers","."),4107715). assertion_content_comment('oboGo_GammaTubulinlargecomplex',s("A","complex","of","gamma","tubulin","and","associated","proteins","thought","to","be","formed","by","multimerization","of","gamma-tubulin","small","complexes",".","An","example","of","this","structure","is","found","in","Schizosaccharomyces","pombe","."),3979361). assertion_content_comment('oboGo_GammaTubulinlargecomplexspindlepolebody',s("A","complex","of","gamma","tubulin","and","associated","proteins","thought","to","be","formed","by","multimerization","of","gamma-tubulin","small","complexes","located","in","the","spindle","pole","body","."),4107727). assertion_content_comment('oboGo_GammaTubulinringcomplexcentrosomal',s("A","centrosome-localized","multiprotein","complex","composed","of","gamma-tubulin","and","other","non-tubulin","proteins","assembled","into","a","ring","structure","that","is","thought","to","be","the","unit","of","nucleation","at","the","minus","end","of","a","microtubule",".","Gamma-tubulin","small","complexes","are","thought","to","be","the","core","repeating","units","of","the","ring","."),3979367). assertion_content_comment('oboGo_GammaTubulinringcomplex',s("A","multiprotein","complex","composed","of","gamma-tubulin","and","other","non-tubulin","proteins","that","forms","a","flexible","open","ring","structure","thought","to","be","the","unit","of","nucleation","at","the","minus","end","of","a","microtubule","."),3979363). assertion_content_comment('oboGo_GammaTubulinsmallcomplexcentrosomal',s("A","centrosomal","complex","usually","comprising","two","gamma-tubulin","molecules",",","at","least","two","conserved","non-tubulin","proteins","that","multimerize","along","with","additional","non-tubulin","proteins","in","animal","cells","into","larger","functional","complexes",".","Gamma-tubulin","small","complexes","are","thought","to","be","the","repeating","unit","making","up","the","core","of","the","gamma-tubulin","ring","complex",".","An","example","of","this","structure","is","found","in","Mus","musculus","."),4363584). assertion_content_comment('oboGo_GammaTubulinsmallcomplex',s("A","complex","usually","comprising","two","gamma-tubulin","molecules","and","two","conserved","non-tubulin","proteins",".","Some","gamma-tubulin","small","complexes","are","thought","to","be","the","repeating","unit","making","up","the","core","of","the","gamma-tubulin","ring","complex","."),3979394). assertion_content_comment('oboGo_GammaTubulinsmallcomplexspindlepolebody',s("A","complex","composed","of","two","gamma-tubulin","molecules","and","conserved","non-tubulin","proteins","isolated","by","fractionation","from","cells",".","The","complex",",","approximately","6S-9S",",","is","analogous","to","the","small","complex","in","animal","cells","but","contains","fewer","subunits",",","and","is","not","thought","to","multimerize","into","larger","functional","units",",","like","complexes","in","those","organisms",".","An","example","of","this","structure","is","found","in","Saccharomyces","cerevisiae","."),3979398). assertion_content_comment('oboGo_GapJunctionHemiChannelactivity',s("A","wide","pore","channel","activity","that","enables","the","transport","of","a","solute","across","a","membrane","via","a","gap","junction","hemi-channel",".","Two","gap","junction","hemi-channels","coupled","together","form","a","complete","gap","junction","."),4107483). assertion_content_comment('oboGo_GastrinInducedgastricacidsecretion',s("The","regulated","release","of","gastric","acid","induced","by","the","interaction","of","gastrin","with","its","receptor","."),4383814). assertion_content_comment('oboGo_GastrinReleasingpeptidereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","gastrin-releasing","peptide","receptor","."),4323053). assertion_content_comment('oboGo_GastroIntestinalsystemsmoothmusclecontraction',s("A","process","in","which","force","is","generated","within","smooth","muscle","tissue",",","resulting","in","a","change","in","muscle","geometry",".","This","process","occurs","in","the","gastro-intestinal","system",".","Force","generation","involves","a","chemo-mechanical","energy","conversion","step","that","is","carried","out","by","the","actin/myosin","complex","activity",",","which","generates","force","through","ATP","hydrolysis",".","The","gastro-intestinal","system","generally","refers","to","the","digestive","structures","stretching","from","the","mouth","to","anus",",","but","does","not","include","the","accessory","glandular","organs","(","liver",",","pancreas","and","biliary","tract",")"),4321152). assertion_content_comment('oboGo_GATA1Tal1Tcf3Lmo2complex',s("A","protein","complex","that","contains","the","zinc","finger","transcription","factor","GATA1",",","the","LIM","domain","protein","Lmo2","(","RBTN2",")",",","the","basic","helix-loop-helix","protein","TAL1","and","its","binding","partner","TCF3",".","The","complex","is","involved","transcriptional","regulation","in","hematopoiesis","."),4173365). assertion_content_comment('oboGo_GATA2Tal1Tcf3Lmo2complex',s("A","protein","complex","that","contains","the","zinc","finger","transcription","factor","GATA2",",","the","LIM","domain","protein","Lmo2","(","RBTN2",")",",","the","basic","helix-loop-helix","protein","TAL1","and","its","binding","partner","TCF3",".","The","complex","is","involved","transcriptional","regulation","in","hematopoiesis","."),4173375). assertion_content_comment('oboGo_GAUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GAU","codon","."),4339456). assertion_content_comment('oboGo_GCACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GCA","codon","."),4339434). assertion_content_comment('oboGo_GCCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GCC","codon","."),4339423). assertion_content_comment('oboGo_GCGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GCG","codon","."),4339445). assertion_content_comment('oboGo_GCUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GCU","codon","."),4339504). assertion_content_comment('oboGo_GDP_4_Dehydro_6_Deoxy_D_MannoseReductaseActivity',s("Catalysis","of","the","reaction",":","GDP-6-deoxy-D-mannose","+","NAD","(","P",")","+","=","GDP-4-dehydro-6-deoxy-D-mannose","+","NAD","(","P",")","H","+","H","+"),4341778). assertion_content_comment('oboGo_GDP_4_Dehydro_D_RhamnoseReductaseActivity',s("Catalysis","of","the","reaction",":","GDP-6-deoxy-D-mannose","+","NAD","(","P",")","+","=","GDP-4-dehydro-6-deoxy-D-mannose","+","NAD","(","P",")","H","+","H","+","In","the","reverse","reaction",",","a","mixture","of","GDP-D-rhamnose","and","its","C-4","epimer","is","formed","."),4313007). assertion_content_comment('oboGo_GDP_6_Deoxy_D_Talose4_DehydrogenaseActivity',s("Catalysis","of","the","reaction",":","GDP-6-deoxy-D-talose","+","NAD","(","P",")","+","=","GDP-4-dehydro-6-deoxy-D-talose","+","NAD","(","P",")","H","+","H","+"),4378188). assertion_content_comment('oboGo_GDPAlphaDMannosylchitobiosyldiphosphodolicholbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-alpha-D-mannosylchitobiosyldiphosphodolichol",",","a","substance","composed","of","mannosylchitobiosyldiphosphodolichol","in","glycosidic","linkage","with","guanosine","diphosphate","."),4240366). assertion_content_comment('oboGo_GDPAlphaDMannosylchitobiosyldiphosphodolicholmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","GDP-alpha-D-mannosylchitobiosyldiphosphodolichol",",","a","substance","composed","of","mannosylchitobiosyldiphosphodolichol","in","glycosidic","linkage","with","guanosine","diphosphate","."),4240363). assertion_content_comment('oboGo_GDPDGlucosephosphorylaseactivity',s("Catalysis","of","the","reaction",":","GDP-D-glucose","+","phosphate","=","D-glucose-1-P","+","GDP","."),4181966). assertion_content_comment('oboGo_GDPDissociationinhibitoractivity',s("Prevents","the","dissociation","of","GDP","from","a","GTPase",",","thereby","preventing","GTP","from","binding","."),4215197). assertion_content_comment('oboGo_GDPDissociationinhibitorbinding',s("Interacting","selectively","and","non-covalently","with","a","GDP-dissociation","inhibitor","protein","."),4279236). assertion_content_comment('oboGo_GDPDRhamnosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-D-rhamnose",",","a","substance","composed","of","rhamnose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4239121). assertion_content_comment('oboGo_GDPDRhamnosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","GDP-D-rhamnose",",","a","substance","composed","of","rhamnose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4239118). assertion_content_comment('oboGo_GDPFucosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","GDP-fucose","from","one","side","of","the","membrane","to","the","other",".","GDP-fucose","is","a","substance","composed","of","fucose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4219455). assertion_content_comment('oboGo_GDPFucosetransport',s("The","directed","movement","of","GDP-fucose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","GDP-fucose","is","a","substance","composed","of","fucose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4291302). assertion_content_comment('oboGo_GDP_Galactose_Glucose_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","GDP-L-galactose","+","alpha-D-glucose","1-phosphate","=","alpha-L-galactose-1-phosphate","+","GDP-alpha-D-glucose","."),4332850). assertion_content_comment('oboGo_GDP_Galactose_Mannose_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","GDP-L-galactose","+","alpha-D-mannose","1-phosphate","=","GDP-alpha-D-mannose","+","alpha-L-galactose-1-phosphate","."),4332861). assertion_content_comment('oboGo_GDP_Galactose_Myoinositol_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","GDP-L-galactose","+","myo-inositol","1-phosphate","=","alpha-L-galactose-1-phosphate","+","GDP-myoinositol","."),4332882). assertion_content_comment('oboGo_GDPGlucosidaseactivity',s("Catalysis","of","the","reaction",":","GDP-D-glucose","+","H","(","2",")","O","=","D-glucose","+","GDP","+","H","(","+",")"),4378199). assertion_content_comment('oboGo_GDPLFucosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-L-fucose",",","a","substance","composed","of","L-fucose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4313057). assertion_content_comment('oboGo_GDPLFucosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","GDP-L-fucose",",","a","substance","composed","of","L-fucose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4313054). assertion_content_comment('oboGo_GDPLFucosesalvage',s("The","formation","of","GDP-L-fucose","from","L-fucose",",","without","de","novo","synthesis",".","L-fucose","is","phosphorylated","by","fucokinase","and","then","converted","by","fucose-1-phosphate","guanylyltransferase","(","EC",":","2.7.7.30",")"),4313064). assertion_content_comment('oboGo_GDPLFucosesynthaseactivity',s("Catalysis","of","the","reaction",":","GDP-L-fucose","+","NAD","+","=","GDP-4-dehydro-6-deoxy-D-mannose","+","NADH","+","H","+"),4267946). assertion_content_comment('oboGo_GDPLGalactosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-L-galactose",",","a","substance","composed","of","L-galactose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4339172). assertion_content_comment('oboGo_GDPLGalactosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","GDP-L-galactose",",","a","substance","composed","of","L-galactose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4339169). assertion_content_comment('oboGo_GDPLGalactosephosphorylaseactivity',s("Catalysis","of","the","reaction",":","GDP-L-galactose","+","phosphate","=","L-galactose-1-P","+","GDP","."),4181957). assertion_content_comment('oboGo_GDPMannose35Epimeraseactivity',s("Catalysis","of","the","reaction",":","GDP-mannose","=","GDP-L-galactose","."),4378161). assertion_content_comment('oboGo_GDPMannose46Dehydrataseactivity',s("Catalysis","of","the","reaction",":","GDP-alpha-D-mannose","=","GDP-4-dehydro-6-deoxy-alpha-D-mannose","+","H","(","2",")","O","."),4253743). assertion_content_comment('oboGo_GDPMannose6Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","GDP-alpha-D-mannose","+","H","(","2",")","O","+","2","NAD","(","+",")","=","GDP-D-mannuronate","+","3","H","(","+",")","+","2","NADH","."),4378174). assertion_content_comment('oboGo_GDPMannosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","GDP-mannose",",","a","substance","composed","of","mannose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4257290). assertion_content_comment('oboGo_GDPMannosemannosylhydrolaseactivity',s("Catalysis","of","the","reaction",":","GDP-alpha-D-mannose","+","H2O","=","GDP","+","D-mannose","+","H","+"),4252289). assertion_content_comment('oboGo_GDPMannosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","GDP-mannose",",","a","substance","composed","of","mannose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4244789). assertion_content_comment('oboGo_GDP_Mannose_Serine_ProteinMannose_1_PhosphotransferaseActivity',s("Catalysis","of","the","transfer","of","mannose-1-phosphate","to","a","serine","residue","in","a","protein","."),4281818). assertion_content_comment('oboGo_GDPMannosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","GDP-mannose","from","one","side","of","the","membrane","to","the","other",".","GDP-mannose","is","a","substance","composed","of","mannose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4219446). assertion_content_comment('oboGo_GDPMannosetransport',s("The","directed","movement","of","GDP-mannose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","GDP-mannose","is","a","substance","composed","of","mannose","in","glycosidic","linkage","with","guanosine","diphosphate","."),4291347). assertion_content_comment('oboGo_Gemin3Gemin4Gemin5complex',s("A","protein","complex","that","contains","Gemin3","(","DDX20",")",",","Gemin4",",","and","Gemin5",",","and","can","bind","to","snRNAs",";","may","be","an","intermediate","in","SMN","complex","assembly","."),4349172). assertion_content_comment('oboGo_Gemin6Gemin7Unripcomplex',s("A","protein","complex","that","contains","Gemin6",",","Gemin7",",","and","unrip","(","STRAP",")",",","and","can","bind","to","snRNAs",";","may","play","a","role","in","snRNP","assembly","."),4349182). assertion_content_comment('oboGo_GeneConversionAtMatingTypelocusdnadoubleStrandbreakformation',s("The","site-specific","endonucleolytic","cleavage","of","DNA","at","the","mating-type","locus","which","initiates","the","conversion","of","one","mating-type","allele","to","another","."),3978090). assertion_content_comment('oboGo_GeneConversionAtMatingTypelocusdnadoubleStrandbreakprocessing',s("The","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","at","the","mating-type","locus","to","form","a","3","'","single-strand","DNA","overhang","."),4059699). assertion_content_comment('oboGo_GeneConversionAtMatingTypelocusdnarepairsynthesis',s("Synthesis","of","DNA","that","proceeds","from","the","broken","3","'","single-strand","DNA","end","uses","the","homologous","intact","duplex","as","the","template","during","gene","conversion","at","the","mating-type","locus","."),3978079). assertion_content_comment('oboGo_GeneConversionAtMatingTypelocus',s("The","conversion","of","the","mating-type","locus","from","one","allele","to","another","resulting","from","the","recombinational","repair","of","a","site-specific","double-strand","break","at","the","mating-type","locus","with","information","from","a","silent","donor","sequence",".","There","is","no","reciprocal","exchange","of","information","because","the","mating-type","locus","copies","information","from","the","donor","sequence","and","the","donor","sequence","remains","unchanged","."),3978063). assertion_content_comment('oboGo_GenerationOfASignalInvolvedInCellCellsignaling',s("The","cellular","process","that","creates","a","physical","entity","or","change","in","state",",","i.e",".","a","signal",",","that","originates","in","one","cell","and","is","used","to","transfer","information","to","another","cell",".","This","process","begins","with","the","initial","formation","of","the","signal","and","ends","with","the","mature","form","and","placement","of","the","signal","."),3988043). assertion_content_comment('oboGo_GenerationOfMature3Endof5srrnageneratedbyrnapolymeraseiii',s("The","removal","of","extra","uridine","residues","from","the","3","'","end","of","a","5S","pre-rRNA","generated","by","transcription","by","RNA","polymerase","III","to","generate","the","mature","3","'","-end","."),4374893). assertion_content_comment('oboGo_GenerationOfMature3EndoflsuRrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Any","process","involved","in","generating","the","mature","3","'","-end","of","an","LSU-rRNA","derived","from","a","tricistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976104). assertion_content_comment('oboGo_GenerationOfMature5EndoflsuRrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Cleavage","within","ITS2","to","generate","the","mature","5","'","-end","of","an","LSU-rRNA","derived","from","a","tricistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976458). assertion_content_comment('oboGo_GeneSpecifictranscriptionfromrnapolymeraseiipromoter',s("The","specifically","regulated","synthesis","of","RNA","from","DNA","encoding","a","specific","gene","or","set","of","genes","by","RNA","polymerase","II","(","Pol","II",")",",","originating","at","a","Pol","II-specific","promoter",".","In","addition","to","RNA","polymerase","II","and","the","general","transcription","factors",",","specific","transcription","requires","one","or","more","specific","factors","that","bind","to","specific","DNA","sequences","or","interact","with","the","general","transcription","machinery","."),3971080). assertion_content_comment('oboGo_GeneticImprintingAtMatingTypelocus',s("A","genetic","imprinting","process","in","which","a","stable","single-strand","DNA","lesion","triggers","programmed","gene","conversion","at","the","mating-type","locus",",","thereby","restricting","mating-type","interconversion","to","one","of","the","two","sister","chromatids","during","DNA","replication","."),4128798). assertion_content_comment('oboGo_Gentisate12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","2",",","5-dihydroxybenzoate","+","O","(","2",")","=","3-maleylpyruvate","+","H","(","+",")"),4378061). assertion_content_comment('oboGo_GeranoylCoacarboxylaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","bicarbonate","+","geranoyl-CoA","=","3-","(","4-methylpent-3-en-1-yl",")","pent-2-enedioyl-CoA","+","ADP","+","2","H","(","+",")","+","phosphate","."),4377164). assertion_content_comment('oboGo_GeranylateCoATransferaseactivity',s("Catalysis","of","the","reaction",":","geranylate","+","CoASH","=","trans-geranyl-CoA","+","OH-","."),4350647). assertion_content_comment('oboGo_GeranylDiphosphatecyclaseactivity',s("Catalysis","of","the","reaction",":","geranyl","diphosphate","=","(","2S",")","-bornyl","diphosphate","."),4377150). assertion_content_comment('oboGo_GeranylgeranylDiphosphategeranylgeranyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","geranylgeranyl","diphosphate","=","diphosphate","+","prephytoene","diphosphate","."),4301514). assertion_content_comment('oboGo_GeranylgeranylglycerolPhosphategeranylgeranyltransferaseactivity',s("Catalysis","of","the","reaction",":","sn-3-O-","(","geranylgeranyl",")","glycerol","1-phosphate","+","all-trans-geranylgeranyl","diphosphate","=","2",",","3-di-O-","(","geranylgeranyl",")","glycerol","1-phosphate","+","diphosphate","."),4367665). assertion_content_comment('oboGo_GermacreneAsynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","+",")","-","(","R",")","-germacrene","A","+","diphosphate","."),4360617). assertion_content_comment('oboGo_GermacreneDsynthaseactivity',s("Catalysis","of","the","reaction",":","2-trans",",","6-trans-farnesyl","diphosphate","=","(","-",")","-germacrene","D","+","diphosphate","."),4186538). assertion_content_comment('oboGo_GermariumDerivedcystoblastdivision',s("The","four","rounds","of","incomplete","mitosis","undergone","by","a","cystoblast","derived","from","the","germarium","to","form","a","16-cell","cyst",".","Within","the","cyst",",","one","cell","differentiates","into","an","oocyte","while","the","rest","become","nurse","cells",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4103548). assertion_content_comment('oboGo_GermariumDerivedeggchamberformation',s("Construction","of","a","stage-1","egg","chamber","in","the","anterior","part","of","the","germarium",",","from","the","progeny","of","germ-line","and","somatic","stem","cells",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4016880). assertion_content_comment('oboGo_GermariumDerivedfemalegermLinecystencapsulation',s("Formation","of","a","single","follicular","epithelium","around","the","germ-line","derived","cells","of","a","cyst","formed","in","the","germarium",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4051857). assertion_content_comment('oboGo_GermariumDerivedfemalegermLinecystformation',s("Formation","of","a","cluster","of","germ-line","cells",",","in","the","germarium",",","derived","from","a","single","founder","cell","(","cystoblast",")","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4051813). assertion_content_comment('oboGo_GermariumDerivedoocytedifferentiation',s("The","process","in","which","one","relatively","unspecialized","immature","cystocyte","of","the","germ-line","cyst","in","the","germarium","acquires","the","specialized","features","of","an","oocyte",".","An","example","of","this","process","can","be","found","in","Drosophila","melanogaster","."),4016882). assertion_content_comment('oboGo_GermariumDerivedoocytefatedetermination',s("The","cell","fate","determination","process","in","which","a","germarium-derived","cell","becomes","capable","of","differentiating","autonomously","into","an","oocyte","cell","regardless","of","its","environment",";","upon","determination",",","the","cell","fate","cannot","be","reversed",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4016906). assertion_content_comment('oboGo_GermBandextension',s("Elongation","of","the","germ","band","on","the","ventral","side","of","the","embryo",",","accompanied","by","a","halving","in","width",".","The","elongation","process","pushes","the","posterior","midgut","invagination","closed","and","compresses","the","amnioserosa","further","."),4019546). assertion_content_comment('oboGo_GermBandshortening',s("The","spreading","of","the","amnioserosa","from","its","compressed","state","to","cover","the","whole","of","the","dorsal","surface",".","Initiating","in","the","thorax","and","spreading","posteriorly",",","it","is","accompanied","by","the","transition","from","a","parasegmental","to","segmental","division","of","the","embryo","."),4019449). assertion_content_comment('oboGo_GermLinecystencapsulation',s("Formation","of","a","single","follicular","epithelium","around","the","germ-line","derived","cells","of","a","cyst","."),4051850). assertion_content_comment('oboGo_GermLinecystformation',s("Formation","of","a","cluster","of","germ-line","cells","derived","from","a","single","founder","cell","."),4017050). assertion_content_comment('oboGo_GermLineprocessesdownstreamofsexdeterminationsignal',s("The","events","determining","the","germ-line","sexual","phenotype","after","the","initial","transmission","of","that","phenotype","to","germ-line-specific","information","pathways","."),4015928). assertion_content_comment('oboGo_GermLinesexdetermination',s("The","determination","of","sex","and","sexual","phenotype","in","an","organism","'","s","germ","line","."),4015908). assertion_content_comment('oboGo_GermLinestemcelldivision',s("The","self-renewing","division","of","a","germline","stem","cell","to","produce","a","daughter","stem","cell","and","a","daughter","germ","cell",",","which","will","divide","to","form","the","gametes","."),4080592). assertion_content_comment('oboGo_GermLinestemcellmaintenance',s("Any","process","involved","in","preventing","uncommitted","germ-line","stem","cells","from","differentiating","as","another","cell","type","."),4309275). assertion_content_comment('oboGo_GermLinestemCellnichehomeostasis',s("A","homeostatic","process","involved","in","the","maintenance","of","an","internal","steady","state","within","the","germ-line","stem-cell","niche",".","This","includes","control","of","cellular","proliferation","and","death","and","control","of","metabolic","function","that","allows","the","niche","to","continue","to","function",".","A","gem-line","stem-cell","niche","is","an","anatomical","structure","that","regulates","how","germ-line","stem-cells","are","used","and","saves","them","from","depletion","."),4160102). assertion_content_comment('oboGo_GGACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GGA","codon","."),4339610). assertion_content_comment('oboGo_GGCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GGC","codon","."),4339644). assertion_content_comment('oboGo_GGGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GGG","codon","."),4339621). assertion_content_comment('oboGo_GGUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GGU","codon","."),4339632). assertion_content_comment('oboGo_GibberellicAcidMediatedSignalingPathwayGAlphaDependent',s("A","series","of","molecular","signals","mediated","by","the","detection","of","gibberellic","acid","and","dependent","on","the","coupling","of","the","alpha","subunit","of","G","proteins","to","the","hormone","receptors","."),4312808). assertion_content_comment('oboGo_GibberellicAcidMediatedSignalingPathwayGAlphaIndependent',s("A","series","of","molecular","signals","mediated","by","the","detection","of","gibberellic","acid","and","not","dependent","on","the","coupling","of","the","alpha","subunit","of","G","proteins","to","the","hormone","receptors","."),4312798). assertion_content_comment('oboGo_Gibberellin12Aldehydeoxidaseactivity',s("Catalysis","of","the","reaction",":","gibberellin","12-aldehyde","+","NADPH","+","H","+","+","O2","=","gibberellin","12","+","NADP","+","+","H2O",".","This","is","the","third","of","three","successive","reactions","resulting","in","the","oxidation","of","ent-kaurenoate","(","ent-kaurenoic","acid",")","to","gibberellin","12","(","GA12",")"),4280352). assertion_content_comment('oboGo_Gibberellin20Oxidaseactivity',s("Catalysis","of","the","oxidation","of","C-20","gibberellins","to","form","the","corresponding","C-19","lactones","."),4299315). assertion_content_comment('oboGo_Gibberellin2BetaDioxygenaseactivity',s("Catalysis","of","the","reaction",":","a","gibberellin","+","2-oxoglutarate","+","O2","=","a","2-beta-hydroxygibberellin","+","succinate","+","CO2","."),4191564). assertion_content_comment('oboGo_Gibberellin3BetaDioxygenaseactivity',s("Catalysis","of","the","reaction",":","a","gibberellin","+","2-oxoglutarate","+","O2","=","a","3-beta-hydroxy-gibberellin","+","succinate","+","CO2","."),4301209). assertion_content_comment('oboGo_Gibberellin_44DioxygenaseActivity',s("Catalysis","of","the","reaction",":","gibberellin","44","+","2-oxoglutarate","+","O2","=","gibberellin","19","+","succinate","+","CO2","."),4377068). assertion_content_comment('oboGo_GibberellinBetaDGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","gibberellin","=","UDP","+","gibberellin","2-O-beta-D-glucoside","."),4377054). assertion_content_comment('oboGo_GibberellinCarboxylOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","GA","=","S-adenosyl-L-homocysteine","+","GA","methyl","ester","."),4332012). assertion_content_comment('oboGo_GlialCellLineDerivedneurotrophicfactorreceptoractivity',s("Combining","with","glial","cell","line-derived","neurotrophic","factor","to","initiate","a","change","in","cell","activity","."),4304154). assertion_content_comment('oboGo_GlialCellLineDerivedneurotrophicfactorreceptorbinding',s("A","growth","factor","that","binds","to","glial","cell","line-derived","neurotrophic","factor","receptors","."),4311032). assertion_content_comment('oboGo_GlobalGenomeNucleotideExcisionrepair',s("The","nucleotide-excision","repair","process","in","which","DNA","lesions","are","removed","from","nontranscribed","strands","and","from","transcriptionally","silent","regions","over","the","entire","genome","."),4178301). assertion_content_comment('oboGo_GlobosideAlphaNAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-galactosaminyl-","(","1",",","3",")","-D-galactosyl-","(","1",",","4",")","-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP-N-acetylgalactosamine","=","N-acetyl-D-galactosaminyl-N-acetyl-D-galactosaminyl-","(","1",",","3",")","-D-galactosyl-","(","1",",","4",")","-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP","."),4367554). assertion_content_comment('oboGo_Glucan13AlphaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","1",",","3-alpha-D-glucosidic","links","in","1",",","3-alpha-D-glucans","."),4344231). assertion_content_comment('oboGo_Glucan14AlphaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","terminal","1",",","4-linked","alpha-D-glucose","residues","successively","from","non-reducing","ends","of","the","chains","with","release","of","beta-D-glucose","."),4208266). assertion_content_comment('oboGo_Glucan14AlphaMaltohexaosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-alpha-D-glucosidic","linkages","in","amylaceous","polysaccharides",",","to","remove","successive","maltohexaose","residues","from","the","non-reducing","chain","ends","."),4344702). assertion_content_comment('oboGo_Glucan14AlphaMaltohydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","(","1-","&","gt",";","4",")","-alpha-D-glucosidic","linkages","in","polysaccharides","so","as","to","remove","successive","alpha-maltose","residues","from","the","non-reducing","ends","of","the","chains","."),4328944). assertion_content_comment('oboGo_Glucan14AlphaMaltotetraohydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-alpha-D-glucosidic","linkages","in","amylaceous","polysaccharides",",","to","remove","successive","maltotetraose","residues","from","the","non-reducing","chain","ends","."),4344341). assertion_content_comment('oboGo_Glucan14AlphaMaltotriohydrolaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-alpha-D-glucosidic","linkages","in","amylaceous","polysaccharides",",","to","remove","successive","maltotriose","residues","from","the","non-reducing","chain","ends","."),4344764). assertion_content_comment('oboGo_Glucan14BetaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-linkages","in","1",",","4-beta-D-glucans",",","to","remove","successive","glucose","units","."),4319930). assertion_content_comment('oboGo_Glucan16AlphaGlucosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","6-alpha-D-glucosidic","linkages","in","1",",","6-alpha-D-glucans","and","derived","oligosaccharides","."),4328838). assertion_content_comment('oboGo_Glucan16AlphaIsomaltosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","6-alpha-D-glucosidic","linkages","in","polysaccharides",",","to","remove","successive","isomaltose","units","from","the","non-reducing","ends","of","the","chains","."),4344638). assertion_content_comment('oboGo_GlucanEndo_12_Beta_GlucosidaseActivity',s("Catalysis","of","the","random","hydrolysis","of","1",",","2-glucosidic","linkages","in","1",",","2-beta-D-glucans","."),4344290). assertion_content_comment('oboGo_GlucanEndo_13_Alpha_GlucosidaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","3-alpha-D-glucosidic","linkages","in","isolichenin",",","pseudonigeran","and","nigeran","."),4287197). assertion_content_comment('oboGo_GlucanEndo_13_Beta_D_GlucosidaseActivity',s("Catalysis","of","the","hydrolysis","of","1",",","3-beta-D-glucosidic","linkages","in","1",",","3-beta-D-glucans","."),4316099). assertion_content_comment('oboGo_GlucanEndo_16_Beta_GlucosidaseActivity',s("Catalysis","of","the","random","hydrolysis","of","1",",","6-linkages","in","1",",","6-beta-D-glucans","."),4359124). assertion_content_comment('oboGo_GlucanExo_13_Beta_GlucosidaseActivity',s("Catalysis","of","the","successive","hydrolysis","of","beta-D-glucose","units","from","the","non-reducing","ends","of","1",",","3-beta-D-glucans",",","releasing","alpha-glucose","."),4208302). assertion_content_comment('oboGo_GlucarateOHydroxycinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucarate","+","sinapoyl-CoA","=","2-O-sinapoyl-D-glucarate","+","CoA","."),4366354). assertion_content_comment('oboGo_GlucarolactoneOHydroxycinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","glucarolactone","+","sinapoyl-CoA","=","O-sinapoylglucarolactone","+","CoA","."),4366344). assertion_content_comment('oboGo_Glucomannan4BetaMannosyltransferaseactivity',s("Catalysis","of","the","reaction",":","glucomannan","(","n",")","+","GDP-mannose","=","glucomannan","(","n","+","1",")","+","GDP","."),4367287). assertion_content_comment('oboGo_Gluconate2Dehydrogenaseacceptoractivity',s("Catalysis","of","the","reaction",":","D-gluconate","+","acceptor","=","2-dehydro-D-gluconate","+","reduced","acceptor","."),4341929). assertion_content_comment('oboGo_Gluconate2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-gluconate","+","NADP","+","=","2-dehydro-D-gluconate","+","NADPH","+","H","+"),4249679). assertion_content_comment('oboGo_Gluconate5Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-gluconate","+","NADP","+","=","5-dehydro-D-gluconate","+","NADPH","+","H","+"),4249692). assertion_content_comment('oboGo_GlucosaminateAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","D-glucosaminate","=","2-dehydro-3-deoxy-D-gluconate","+","NH3","."),4376917). assertion_content_comment('oboGo_Glucosamine_1_PhosphateN_AcetyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucosamine","1-phosphate","+","acetyl-CoA","=","N-acetyl-alpha-D-glucosamine","1-phosphate","+","CoA","+","H","(","+",")"),4237300). assertion_content_comment('oboGo_Glucosamine_6_PhosphateDeaminaseActivity',s("Catalysis","of","the","reaction",":","D-glucosamine","6-phosphate","+","H","(","2",")","O","=","beta-D-fructose","6-phosphate","+","NH","(","4",")","(","+",")"),4207876). assertion_content_comment('oboGo_Glucosamine6PhosphatenAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucosamine","6-phosphate","+","acetyl-CoA","=","N-acetyl-D-glucosamine","6-phosphate","+","CoA","+","H","(","+",")"),4207854). assertion_content_comment('oboGo_GlucosamineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucosamine","+","acetyl-CoA","=","N-acetyl-D-glucosamine","+","CoA","+","H","(","+",")"),4376962). assertion_content_comment('oboGo_GlucosaminylgalactosylglucosylceramideBetaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosaminyl-","(","1",",","3",")","-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP-galactose","=","D-galactosyl-N-acetyl-D-glucosaminyl-","(","1",",","3",")","-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP","."),4367420). assertion_content_comment('oboGo_GlucosaminylPhosphotidylinositoloAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","glucosaminyl-phosphotidylinositol","+","fatty","acyl-CoA","=","glucosaminyl-acyl-phosphotidylinositol","+","CoA","."),4329724). assertion_content_comment('oboGo_Glucose_16_BisphosphateSynthaseActivity',s("Catalysis","of","the","reaction",":","3-phospho-D-glyceroyl","phosphate","+","alpha-D-glucose","1-phosphate","=","3-phospho-D-glycerate","+","alpha-D-glucose","1",",","6-bisphosphate","+","H","(","+",")"),4376975). assertion_content_comment('oboGo_Glucose1Dehydrogenasenadactivity',s("Catalysis","of","the","reaction",":","D-glucose","+","NAD","+","=","D-glucono-1",",","5-lactone","+","NADH","."),4377332). assertion_content_comment('oboGo_Glucose1_DehydrogenaseNADPActivity_3',s("Catalysis","of","the","reaction",":","D-glucose","+","NADP","+","=","D-glucono-1",",","4-lactone","+","NADPH","."),4377319). assertion_content_comment('oboGo_Glucose1Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","beta-D-glucose","+","NAD","(","P",")","+","=","D-glucono-1",",","5-lactone","+","NAD","(","P",")","H","."),4377307). assertion_content_comment('oboGo_Glucose_1_PhosphataseActivity',s("Catalysis","of","the","reaction",":","D-glucose","1-phosphate","+","H2O","=","D-glucose","+","phosphate","."),4249769). assertion_content_comment('oboGo_Glucose_1_PhosphateAdenylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","1-phosphate","+","ATP","=","ADP-glucose","+","diphosphate","."),4249781). assertion_content_comment('oboGo_Glucose_1_PhosphateAdenylyltransferaseComplex',s("Complex","that","catalyzes","the","synthesis","of","ADP-glucose","and","pyrophosphate","from","glucose-1-phosphate","and","ATP",".","In","plants",",","the","complex","is","a","heterotetramer","composed","of","two","types","of","subunits","(","small","and","large",")","In","bacteria",",","the","enzyme","complex","is","composed","of","four","identical","subunits","."),4334152). assertion_content_comment('oboGo_Glucose_1_PhosphateCytidylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","1-phosphate","+","CTP","=","CDP-D-glucose","+","diphosphate","."),4368141). assertion_content_comment('oboGo_Glucose_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","1-phosphate","+","GTP","=","diphosphate","+","GDP-D-glucose","."),4368125). assertion_content_comment('oboGo_Glucose_1_PhosphateGuanylyltransferaseGDPActivity',s("Catalysis","of","the","reaction",":","GDP","+","D-glucose","1-phosphate","=","phosphate","+","GDP-glucose","."),4332872). assertion_content_comment('oboGo_Glucose1Phosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","glucose","1-phosphate",",","a","monophosphorylated","derivative","of","glucose","with","the","phosphate","group","attached","to","C-1","."),4225191). assertion_content_comment('oboGo_Glucose_1_PhosphatePhosphodismutaseActivity',s("Catalysis","of","the","reaction",":","2","D-glucose","1-phosphate","=","D-glucose","+","D-glucose","1",",","6-bisphosphate","."),4377294). assertion_content_comment('oboGo_Glucose1Phosphatephosphorylation',s("The","process","of","introducing","a","phosphate","group","into","glucose","1-phosphate","to","produce","glucose","bisphosphate","."),4225207). assertion_content_comment('oboGo_Glucose_1_PhosphateThymidylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","1-phosphate","+","dTTP","=","diphosphate","+","dTDP-glucose","."),4249804). assertion_content_comment('oboGo_Glucose_1_Phospho_D_MannosylglycoproteinPhosphodiesteraseActivity',s("Catalysis","of","the","reaction",":","H2O","+","6-","(","D-glucose-1-phospho",")","-D-mannosylglycoprotein","=","D-mannosylglycoprotein","+","D-glucose-alpha-1-phosphate","."),4368421). assertion_content_comment('oboGo_Glucose_6_PhosphataseActivity',s("Catalysis","of","the","reaction",":","D-glucose","6-phosphate","+","H2O","=","D-glucose","+","phosphate","."),4207967). assertion_content_comment('oboGo_Glucose_6_Phosphate1_EpimeraseActivity',s("Catalysis","of","the","reaction",":","alpha-D-glucose","6-phosphate","=","beta-D-glucose","6-phosphate","."),4377281). assertion_content_comment('oboGo_Glucose_6_PhosphateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","D-glucose","6-phosphate","+","NADP","+","=","D-glucono-1",",","5-lactone","6-phosphate","+","NADPH","+","H","+"),4207979). assertion_content_comment('oboGo_Glucose_6_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-glucose","6-phosphate","=","D-fructose","6-phosphate","."),4207944). assertion_content_comment('oboGo_Glucose6Phosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","glucose","6-phosphate",",","a","monophosphorylated","derivative","of","glucose","with","the","phosphate","group","attached","to","C-6","."),4287392). assertion_content_comment('oboGo_Glucose6Phosphate_Phosphateantiporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glucose","6-phosphate","(","out",")","+","phosphate","(","in",")","=","glucose","6-phosphate","(","in",")","+","phosphate","(","out",")"),4020544). assertion_content_comment('oboGo_Glucose_6_PhosphateTransmembraneTransporterActivity',s("Catalysis","of","the","transfer","of","glucose-6-phosphate","from","one","side","of","the","membrane","to","the","other",".","Glucose-6-phosphate","is","a","monophosphorylated","derivative","of","glucose","with","the","phosphate","group","attached","to","C-6","."),4297450). assertion_content_comment('oboGo_Glucose_6_PhosphateTransport',s("The","directed","movement","of","glucose-6-phosphate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Glucose-6-phosphate","is","a","monophosphorylated","derivative","of","glucose","with","the","phosphate","group","attached","to","C-6","."),4291121). assertion_content_comment('oboGo_GlucoseCatabolicProcessToDLactateandethanol',s("The","anaerobic","chemical","reactions","and","pathways","resulting","in","the","enzymatic","breakdown","of","D-glucose","to","D-lactate","and","ethanol",",","yielding","energy","in","the","form","of","adenosine","triphosphate","(","ATP",")","at","the","rate","of","one","ATP","per","glucose","molecule","."),4244372). assertion_content_comment('oboGo_GlucoseFructoseoxidoreductaseactivity',s("Catalysis","of","the","reaction",":","D-fructose","+","D-glucose","=","D-glucitol","+","D-glucono-1",",","5-lactone","."),4364737). assertion_content_comment('oboGo_Glucoside3Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","sucrose","+","acceptor","=","3-dehydro-alpha-D-glucosyl-beta-D-fructofuranoside","+","reduced","acceptor","."),4342652). assertion_content_comment('oboGo_GlucosylDnabetaGlucosyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","beta-D-glucosyl","residue","from","UDP-glucose","to","a","glucosylhydroxymethylcytosine","residue","in","DNA","."),4343213). assertion_content_comment('oboGo_Glucosylglycerol3Phosphataseactivity',s("Catalysis","of","the","reaction",":","2-O-","(","beta-D-glucosyl",")","-sn-glycerol","3-phosphate","+","H","(","2",")","O","=","2-O-","(","beta-D-glucosyl",")","-sn-glycerol","+","phosphate","."),4268649). assertion_content_comment('oboGo_GlucosylglycerolPhosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","ADP-glucose","=","2-O-","(","beta-D-glucosyl",")","-sn-glycerol","3-phosphate","+","ADP","+","H","(","+",")"),4343186). assertion_content_comment('oboGo_Glucuronate_1_PhosphateUridylyltransferaseActivity',s("Catalysis","of","the","reaction",":","1-phospho-alpha-D-glucuronate","+","UTP","=","diphosphate","+","UDP-alpha-D-glucuronate","."),4367985). assertion_content_comment('oboGo_Glucuronate_2_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","2-sulfate","groups","of","the","2-O-sulfo-D-glucuronate","residues","of","chondroitin","sulfate",",","heparin","and","heparitin","sulfate","."),4296751). assertion_content_comment('oboGo_GlucuronateCatabolicProcessToXylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glucuronate","into","other","compounds",",","including","xylulose","5-phosphate","."),4244170). assertion_content_comment('oboGo_GlucuronoarabinoxylanEndo_14_Beta_XylanaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-xylosyl","links","in","some","glucuronoarabinoxylans","."),4344868). assertion_content_comment('oboGo_GlucuronosylDisulfoglucosamineglucuronidaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","3-D-glucuronosyl-N2-",",","6-disulfo-beta-D-glucosamine","=","glucuronate","+","N2",",","6-disulfo-D-glucosamine","."),4370408). assertion_content_comment('oboGo_GlucuronosylNAcetylgalactosaminylProteoglycan4BetaNAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucuronyl-N-acetyl-1",",","3-beta-D-galactosaminylproteoglycan","+","UDP-N-acetylgalactosamine","=","N-acetyl-D-galactosaminyl-1",",","4-beta-D-glucuronyl-N-acetyl-1",",","3-beta-D-galactosaminylproteoglycan","+","UDP","."),4366898). assertion_content_comment('oboGo_GlucuronosylNAcetylglucosaminylProteoglycan4AlphaNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","beta-D-glucuronosyl-","(","1",",","4",")","-N-acetyl-alpha-D-glucosaminyl-proteoglycan","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-alpha-D-glucosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-","(","1",",","4",")","-N-acetyl-alpha-D-glucosaminyl-proteoglycan","+","UDP","."),4269649). assertion_content_comment('oboGo_Glucuronoxylan4OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","glucuronoxylan","D-glucuronate","=","S-adenosyl-L-homocysteine","+","glucuronoxylan","4-O-methyl-D-glucuronate","."),4309166). assertion_content_comment('oboGo_GlucuronylGalactosylProteoglycan4AlphaNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-glucuronosyl-","(","1",",","3",")","-beta-D-galactosyl-","(","1",",","3",")","-beta-D-galactosyl-","(","1",",","4",")","-beta-D-xylosyl-proteoglycan","=","UDP","+","alpha-N-acetyl-D-glucosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-","(","1",",","3",")","-beta-D-galactosyl-","(","1",",","3",")","-beta-D-galactosyl-","(","1",",","4",")","-beta-D-xylosyl-proteoglycan","."),4384462). assertion_content_comment('oboGo_Glucuronylgalactosylproteoglycan4BetaNAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-glucuronyl-1",",","3-beta-D-galactosylproteoglycan","+","UDP-N-acetylgalactosamine","=","N-acetyl-D-galactosaminyl-1",",","4-beta-D-glucuronyl-1",",","3-beta-D-galactosylproteoglycan","+","UDP","."),4366914). assertion_content_comment('oboGo_GlutaconateCoATransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","(","E",")","-glutaconate","=","acetate","+","glutaconyl-1-CoA","."),4275089). assertion_content_comment('oboGo_GlutaconylCoadecarboxylaseactivity',s("Catalysis","of","the","reaction",":","trans-glutaconyl-CoA","+","H","(","+",")","=","but-2-enoyl-CoA","+","CO","(","2",")"),4273991). assertion_content_comment('oboGo_Glutamate1Kinaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","=","alpha-L-glutamyl","phosphate","+","ADP","+","H","(","+",")"),4377198). assertion_content_comment('oboGo_Glutamate_1_Semialdehyde21_AminomutaseActivity',s("Catalysis","of","the","reaction",":","(","S",")","-4-amino-5-oxopentanoate","=","5-aminolevulinate","."),4314145). assertion_content_comment('oboGo_Glutamate5Kinaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","=","L-glutamyl","5-phosphate","+","ADP","+","H","(","+",")"),4208019). assertion_content_comment('oboGo_Glutamate_5_SemialdehydeDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","L-glutamate","5-semialdehyde","+","NADP","(","+",")","+","phosphate","=","L-glutamyl","5-phosphate","+","H","(","+",")","+","NADPH","."),4207616). assertion_content_comment('oboGo_GlutamateAmmonialigaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","+","NH","(","4",")","(","+",")","=","L-glutamine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4207743). assertion_content_comment('oboGo_GlutamateAmmoniaLigaseadenylyltransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","[","L-glutamate",":","ammonia","ligase","(","ADP-forming",")","]","=","diphosphate","+","adenylyl-","[","L-glutamate",":","ammonia","ligase","(","ADP-forming",")","]"),4249213). assertion_content_comment('oboGo_GlutamateCatabolicProcessTo2Oxoglutarate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate","into","other","compounds",",","including","2-oxoglutarate","."),4243042). assertion_content_comment('oboGo_GlutamateCatabolicProcessVia2Hydroxyglutarate',s("The","anaerobic","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate",",","via","the","intermediate","2-hydroxyglutarate",",","yielding","energy","in","the","form","of","ATP","."),4243029). assertion_content_comment('oboGo_GlutamateCatabolicProcessVia2Oxoglutarate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate",",","via","the","intermediate","2-oxoglutarate","."),4231882). assertion_content_comment('oboGo_GlutamateCatabolicProcessViaLCitramalate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glutamate",",","via","the","intermediate","L-citramalate","."),4243005). assertion_content_comment('oboGo_GlutamateCysteineligaseactivity',s("Catalysis","of","the","reaction",":","L-cysteine","+","L-glutamate","+","ATP","=","L-gamma-glutamyl-L-cysteine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4207826). assertion_content_comment('oboGo_GlutamateCysteineligasecatalyticsubunitbinding',s("Interacting","selectively","and","non-covalently","with","the","catalytic","subunit","of","glutamate-cysteine","ligase","."),4382350). assertion_content_comment('oboGo_GlutamateCysteineligasecomplex',s("An","enzyme","complex","that","catalyzes","the","ligation","of","glutamate","to","cysteine",",","forming","glutamylcysteine","."),4267603). assertion_content_comment('oboGo_GlutamateDehydrogenaseNADPActivity_8',s("Catalysis","of","the","reaction",":","L-glutamate","+","H2O","+","NAD","(","P",")","+","=","2-oxoglutarate","+","NH3","+","NAD","(","P",")","H","+","H","+"),4207708). assertion_content_comment('oboGo_GlutamateEthylamineligaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","+","ethylamine","=","N","(","5",")","-ethyl-L-glutamine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4377218). assertion_content_comment('oboGo_Glutamate_GammaAminobutyricacidantiporteractivity',s("Catalysis","of","the","reaction",":","tyrosine","(","out",")","+","tyramine","(","in",")","=","tyrosine","(","in",")","+","tyramine","(","out",")"),4178053). assertion_content_comment('oboGo_GlutamateGatedcalciumionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","channel","that","opens","when","glutamate","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4333108). assertion_content_comment('oboGo_GlutamateMethylamineligaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","+","methylammonium","=","N","(","5",")","-methyl-L-glutamine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4377176). assertion_content_comment('oboGo_GlutamateNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-acetyl-L-ornithine","+","L-glutamate","=","N-acetyl-L-glutamate","+","L-ornithine","."),4207801). assertion_content_comment('oboGo_GlutamatePrephenateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-arogenate","=","L-glutamate","+","prephenate","."),4343743). assertion_content_comment('oboGo_GlutamatePutrescineligaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","ATP","+","putrescine","=","gamma-L-glutamylputrescine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4361056). assertion_content_comment('oboGo_GlutamateTrnaglnligaseactivity',s("Catalysis","of","the","reaction",":","tRNA","(","Glx",")","+","L-glutamate","+","ATP","=","glutamyl-tRNA","(","Glx",")","+","diphosphate","+","AMP","."),4268323). assertion_content_comment('oboGo_GlutamateTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-glutamate","+","tRNA","(","Glu",")","=","AMP","+","diphosphate","+","L-glutamyl-tRNA","(","Glu",")"),4199931). assertion_content_comment('oboGo_GlutamateTrnaligasecomplex',s("An","enzyme","complex","that","catalyzes","the","ligation","of","glutamate","and","tRNA","(","Glu",")","to","form","glutamyl-tRNA","(","Glu",")"),4259736). assertion_content_comment('oboGo_GlutamicTypeendopeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","internal","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","involving","a","glutamate/glutamine","catalytic","dyad","."),4180833). assertion_content_comment('oboGo_GlutamicTypepeptidaseactivity',s("Catalysis","of","the","hydrolysis","of","peptide","bonds","in","a","polypeptide","chain","by","a","mechanism","involving","a","glutamate/glutamine","catalytic","dyad","."),4180793). assertion_content_comment('oboGo_GlutaminAsparaginAseactivity',s("Catalysis","of","the","reaction",":","H2O","+","L-glutamine","=","NH3","+","L-glutamate",";","and","H2O","+","L-asparagine","=","NH3","+","L-aspartate","."),4266555). assertion_content_comment('oboGo_Glutamine_Fructose_6_PhosphateTransaminaseIsomerizingActivity',s("Catalysis","of","the","reaction",":","beta-D-fructose","6-phosphate","+","L-glutamine","=","D-glucosamine","6-phosphate","+","L-glutamate","."),4207531). assertion_content_comment('oboGo_GlutamineImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","glutamine","(","out",")","=","ADP","+","phosphate","+","glutamine","(","in",")"),4293646). assertion_content_comment('oboGo_GlutamineNAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","L-glutamine","=","CoA","+","N-acyl-L-glutamine","."),4377504). assertion_content_comment('oboGo_GlutamineNPhenylacetyltransferaseactivity',s("Catalysis","of","the","reaction",":","phenylacetyl-CoA","+","L-glutamine","=","CoA","+","alpha-N-phenylacetyl-L-glutamine","."),4377558). assertion_content_comment('oboGo_GlutaminePhenylpyruvatetransaminaseactivity',s("Catalysis","of","the","reaction",":","keto-phenylpyruvate","+","L-glutamine","=","2-oxoglutaramate","+","L-phenylalanine","."),4368893). assertion_content_comment('oboGo_GlutamineScylloInositoltransaminaseactivity',s("Catalysis","of","the","reaction",":","2",",","4",",","6/3",",","5-pentahydroxycyclohexanone","+","L-glutamine","=","1-amino-1-deoxy-scyllo-inositol","+","2-oxoglutaramate","."),4368821). assertion_content_comment('oboGo_GlutamineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-glutamine","+","tRNA","(","Gln",")","=","AMP","+","diphosphate","+","L-glutaminyl-tRNA","(","Gln",")"),4199948). assertion_content_comment('oboGo_GlutaminylPeptidecyclotransferaseactivity',s("Catalysis","of","the","reaction",":","L-glutaminyl-peptide","=","5-oxoprolyl-peptide","+","NH3","."),4305953). assertion_content_comment('oboGo_GlutaminylTrnaaminoacylation',s("The","process","of","coupling","glutamine","to","glutaminyl-tRNA",",","catalyzed","by","glutaminyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-","adenosine","residue","of","the","tRNA","."),4179779). assertion_content_comment('oboGo_GlutaminylTrnaglnbiosynthesisviatransamidation',s("A","tRNA","aminoacylation","process","in","which","glutaminyl-tRNAGln","is","formed","by","a","tRNA-dependent","two-step","pathway",".","In","the","first","step","a","non-discriminating","glutamyl-tRNAGlx","synthetase","generates","the","misacylated","L-glutamyl-tRNAGln","species",",","and","in","the","second","step","it","is","amidated","to","the","correctly","charged","L-glutaminyl-tRNAGln","by","a","glutamyl-tRNAGln","amidotransferase","."),4177306). assertion_content_comment('oboGo_GlutaminylTrnasynthaseglutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","L-glutamine","+","glutamyl-tRNA","(","Gln",")","+","ATP","=","L-glutamate","+","glutaminyl-tRNA","(","Gln",")","+","phosphate","+","ADP","."),4268403). assertion_content_comment('oboGo_GlutamylTrnaaminoacylation',s("The","process","of","coupling","glutamate","to","glutamyl-tRNA",",","catalyzed","by","glutamyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-","adenosine","residue","of","the","tRNA","."),4179799). assertion_content_comment('oboGo_GlutamylTrnaglnamidotransferasecomplex',s("A","protein","complex","that","possesses","glutamyl-tRNA","(","Gln",")","amidotransferase","activity",",","and","therefore","creates","Gln-tRNA","by","amidating","Glu-tRNA",";","usually","composed","of","3","subunits",":","A",",","B",",","and","C",".","Note","that","the","C","subunit","may","not","be","required","in","all","organisms","."),4307371). assertion_content_comment('oboGo_GlutamylTrnareductaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-4-amino-5-oxopentanoate","+","NADP","(","+",")","+","tRNA","(","Glu",")","=","L-glutamyl-tRNA","(","Glu",")","+","H","(","+",")","+","NADPH","."),4249280). assertion_content_comment('oboGo_GlutarateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","CoA","+","glutarate","=","ADP","+","glutaryl-CoA","+","H","(","+",")","+","phosphate","."),4377546). assertion_content_comment('oboGo_GlutarateSemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","glutarate","semialdehyde","+","NAD","+","+","H2O","=","glutarate","+","NADH","."),4377570). assertion_content_comment('oboGo_Glutaryl_7_Aminocephalosporanic_AcidAcylaseActivity',s("Catalysis","of","the","reaction",":","(","7R",")","-7-","(","4-carboxybutanamido",")","cephalosporanate","+","H2O","=","(","7R",")","-7-aminocephalosporanate","+","glutarate","."),4345090). assertion_content_comment('oboGo_GlutarylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","glutaryl-CoA","+","acceptor","=","crotonoyl-CoA","+","CO2","+","reduced","acceptor","."),4207518). assertion_content_comment('oboGo_GlutathioneCoaGlutathionetranshydrogenaseactivity',s("Catalysis","of","the","reaction",":","oxidized","glutathione","+","CoA","=","reduced","glutathione","+","CoA-glutathione","."),4365496). assertion_content_comment('oboGo_GlutathioneCystinetranshydrogenaseactivity',s("Catalysis","of","the","reaction",":","cystine","+","2","reduced","glutathione","=","oxidized","glutathione","+","2","L-cysteine","."),4365511). assertion_content_comment('oboGo_GlutathioneDisulfidereductaseactivity',s("Catalysis","of","the","reaction",":","2","glutathione","+","NADP","+","=","glutathione","disulfide","+","NADPH","+","H","+"),4207497). assertion_content_comment('oboGo_GlutathioneGammaGlutamylcysteinyltransferaseactivity',s("Catalysis","of","the","reaction",":","glutathione","+","Glu","(","-Cys",")","(","n",")","-Gly","=","Gly","+","Glu","(","-Cys",")","(","n","+","1",")","-Gly","."),4301268). assertion_content_comment('oboGo_GlutathioneHomocystinetranshydrogenaseactivity',s("Catalysis","of","the","reaction",":","homocystine","+","2","reduced","glutathione","=","oxidized","glutathione","+","2","homocysteine","."),4365644). assertion_content_comment('oboGo_GlutathioneRegulatedpotassiumexporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","K","+","(","in",")","+","H","+","(","out",")","=","K","+","(","out",")","+","H","+","(","in",")",",","where","glutathione","maintains","the","closed","state","."),4292655). assertion_content_comment('oboGo_GlutathioneSConjugateExportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","glutathione","S-conjugate","(","in",")","=","ADP","+","phosphate","+","glutathione","S-conjugate","(","out",")"),4291853). assertion_content_comment('oboGo_GlutathioneSConjugateTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",",","to","directly","drive","the","transport","of","glutathione","S-conjugate","across","a","membrane","."),4168998). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","glyceraldehyde-3-phosphate",",","an","important","intermediate","in","glycolysis","."),4351463). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateCatabolicProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glyceraldehyde-3-phosphate",",","an","important","intermediate","in","glycolysis","."),4244689). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseActivity',s("Catalysis","of","the","reactions",":","glyceraldehyde","3-phosphate","+","phosphate","+","NAD","(","P",")","+","=","3-phospho-D-glyceroyl-phosphate","+","NAD","(","P",")","H","+","H","+",",","and","glyceraldehyde","3-phosphate","+","H2O","+","NAD","(","P",")","+","=","3-phospho-D-glycerate","+","NAD","(","P",")","H","+","H","+"),4207406). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseFerredoxinActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde-3-phosphate","+","H2O","+","2","oxidized","ferredoxin","=","3-phospho-D-glycerate","+","2","H","+","+","2","reduced","ferredoxin","."),4327682). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseNADNon_PhosphorylatingActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde","3-phosphate","+","NAD","+","+","H2O","=","3-phospho-D-glycerate","+","NADH","+","H","+"),4326823). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseNADPActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde","3-phosphate","+","H","(","2",")","O","+","NADP","(","+",")","=","3-phospho-D-glycerate","+","2","H","(","+",")","+","NADPH","."),4249260). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseNADPhosphorylatingActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde","3-phosphate","+","phosphate","+","NAD","+","=","3-phospho-D-glyceroyl","phosphate","+","NADH","+","H","+"),4207408). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseNADPPhosphorylatingActivity_9',s("Catalysis","of","the","reaction",":","phosphate","+","NADP","+","+","glyceraldehyde-3-phosphate","=","NADPH","+","3-phospho-D-glyceroyl-phosphate","."),4365965). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateDehydrogenaseNADPPhosphorylatingActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde","3-phosphate","+","phosphate","+","NAD","(","P",")","+","=","3-phospho-D-glyceroyl","phosphate","+","NAD","(","P",")","H","+","H","+"),4328772). assertion_content_comment('oboGo_Glyceraldehyde3Phosphate_Inorganicphosphateantiporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glyceraldehyde","3-phosphate","(","out",")","+","phosphate","(","in",")","=","glyceraldehyde","3-phosphate","(","in",")","+","phosphate","(","out",")"),4286815). assertion_content_comment('oboGo_Glyceraldehyde_3_PhosphateMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","glyceraldehyde-3-phosphate",",","an","important","intermediate","in","glycolysis","."),4030707). assertion_content_comment('oboGo_Glycerate2Kinaseactivity',s("Catalysis","of","the","reaction",":","D-glycerate","+","ATP","=","2-phospho-D-glycerate","+","ADP","."),4327628). assertion_content_comment('oboGo_Glycerol_12_Cyclic_Phosphate2_PhosphodiesteraseActivity',s("Catalysis","of","the","reaction",":","glycerol","1",",","2-cyclic","phosphate","+","H","(","2",")","O","=","glycerol","1-phosphate","+","H","(","+",")"),4368512). assertion_content_comment('oboGo_Glycerol_1_PhosphataseActivity',s("Catalysis","of","the","reaction",":","glycerol-1-phosphate","+","H2O","=","glycerol","+","phosphate","."),4345792). assertion_content_comment('oboGo_Glycerol_1_PhosphateDehydrogenaseNADPActivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","sn-glycerol-1-phosphate","=","NAD","(","P",")","H","+","H","+","+","dihydroxy-acetone-phosphate","."),4266402). assertion_content_comment('oboGo_Glycerol2Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","glycerol","+","NADP","(","+",")","=","glycerone","+","H","(","+",")","+","NADPH","."),4377429). assertion_content_comment('oboGo_Glycerol_2_PhosphataseActivity',s("Catalysis","of","the","reaction",":","glycerol","2-phosphate","+","H","(","2",")","O","=","glycerol","+","phosphate","."),4377443). assertion_content_comment('oboGo_Glycerol_2_Phosphate_TransportingATPaseActivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","glycerol-2-phosphate","(","out",")","=","ADP","+","phosphate","+","glycerol-2-phosphate","(","in",")"),4179029). assertion_content_comment('oboGo_Glycerol_2_PhosphateTransport',s("The","directed","movement","of","glycerol-2-phosphate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Glycerol-2-phosphate","is","a","phosphoric","monoester","of","glycerol","."),4178987). assertion_content_comment('oboGo_Glycerol_3_PhosphataseActivity',s("Catalysis","of","the","reaction",":","glycerol","3-phosphate","+","H2O","=","glycerol","+","phosphate","."),4317466). assertion_content_comment('oboGo_Glycerol_3_Phosphate1_DehydrogenaseNADPActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","NADP","(","+",")","=","D-glyceraldehyde","3-phosphate","+","H","(","+",")","+","NADPH","."),4364106). assertion_content_comment('oboGo_Glycerol_3_PhosphateBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","glycerol-3-phosphate",",","a","phosphoric","monoester","of","glycerol","."),4351448). assertion_content_comment('oboGo_Glycerol_3_PhosphateCatabolicProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","glycerol-3-phosphate",",","a","phosphoric","monoester","of","glycerol","."),4351434). assertion_content_comment('oboGo_Glycerol_3_PhosphateCytidylyltransferaseActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","CTP","=","CDP-glycerol","+","diphosphate","."),4368192). assertion_content_comment('oboGo_Glycerol_3_PhosphateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","a","quinone","=","glycerone","phosphate","+","a","quinol","."),4186610). assertion_content_comment('oboGo_Glycerol_3_PhosphateDehydrogenaseComplex',s("An","enzyme","complex","that","catalyzes","the","dehydrogenation","of","sn-glycerol","3-phosphate","to","form","glycerone","phosphate","."),4259747). assertion_content_comment('oboGo_Glycerol_3_PhosphateDehydrogenaseNADActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","NAD","+","=","glycerone","phosphate","+","NADH","+","H","+"),4207567). assertion_content_comment('oboGo_Glycerol_3_PhosphateDehydrogenaseNADPActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","NAD","(","P",")","+","=","glycerone","phosphate","+","NAD","(","P",")","H","+","H","+"),4377414). assertion_content_comment('oboGo_Glycerol_3_Phosphate_GlucosePhosphotransferaseActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","D-glucose","=","D-glucose","6-phosphate","+","glycerol","."),4369035). assertion_content_comment('oboGo_Glycerol_3_PhosphateMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","glycerol-3-phosphate",",","a","phosphoric","monoester","of","glycerol","."),4225094). assertion_content_comment('oboGo_Glycerol_3_PhosphateO_AcyltransferaseActivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","sn-glycerol","3-phosphate","=","CoA","+","1-acyl-sn-glycerol","3-phosphate","."),4207594). assertion_content_comment('oboGo_Glycerol_3_PhosphateOxidaseActivity',s("Catalysis","of","the","reaction",":","sn-glycerol","3-phosphate","+","O","(","2",")","=","glycerone","phosphate","+","H","(","2",")","O","(","2",")"),4207551). assertion_content_comment('oboGo_Glycerol_3_PhosphateTransmembraneTransporterActivity',s("Catalysis","of","the","transfer","of","glycerol-3-phosphate","from","one","side","of","the","membrane","to","the","other",".","Glycerol-3-phosphate","is","a","phosphoric","monoester","of","glycerol","."),4289582). assertion_content_comment('oboGo_Glycerol_3_Phosphate_TransportingATPaseActivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","glycerol-3-phosphate","(","out",")","=","ADP","+","phosphate","+","glycerol-3-phosphate","(","in",")"),4291868). assertion_content_comment('oboGo_Glycerol_3_PhosphateTransport',s("The","directed","movement","of","glycerol-3-phosphate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Glycerol-3-phosphate","is","a","phosphoric","monoester","of","glycerol","."),4291022). assertion_content_comment('oboGo_GlycerolPhosphateImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","glycerol-phosphate","(","out",")","=","ADP","+","phosphate","+","glycerol-phosphate","(","in",")"),4289585). assertion_content_comment('oboGo_GlycerolPhosphate_Inorganicphosphateantiporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glycerol","phosphate","(","out",")","+","inorganic","phosphate","(","in",")","=","glycerol","phosphate","(","in",")","+","inorganic","phosphate","(","out",")"),4292980). assertion_content_comment('oboGo_GlyceronePhosphateoAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","glycerone","phosphate","=","1-acylglycerone","3-phosphate","+","CoA","."),4304520). assertion_content_comment('oboGo_GlycerophospholipidAcyltransferaseCoADependentactivity',s("Catalysis","of","the","reaction",":","1-radyl-2-lyso-sn-glycero-3-phosphoethanolamine","+","1-radyl-2-acyl-sn-glycero-3-phosphocholine","=","1-radyl-2-lyso-sn-glycero-3-phosphocholine","+","1-radyl-2-acyl-sn-glycero-3-phosphoethanolamine","."),4366450). assertion_content_comment('oboGo_GlycerophospholipidArachidonoylTransferasecoaIndependentactivity',s("Catalysis","of","the","reaction",":","1-alkyl-2-lyso-sn-glycero-3-phosphoethanolamine","+","1-alkyl-2-arachidonyl-sn-glycero-3-phosphocholine","=","1-alkyl-2-lyso-sn-glycero-3-phosphocholine","+","1-alkyl-2-arachidonyl-sn-glycero-3-phosphoethanolamine","."),4366415). assertion_content_comment('oboGo_GlycerylEthermonooxygenaseactivity',s("Catalysis","of","the","reaction",":","1-alkyl-sn-glycerol","+","O2","+","(","tetrahydrobiopterin/tetrahydropteridine",")","=","1-hydroxyalkyl-sn-glycerol","+","H2O","+","(","dihydrobiopterin/dihydropteridine",")"),4266376). assertion_content_comment('oboGo_Glycine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","glycine","+","2-oxoglutarate","=","glyoxylate","+","L-glutamate","."),4377726). assertion_content_comment('oboGo_GlycineBetaineTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","glycine","betaine","(","out",")","=","ADP","+","phosphate","+","glycine","betaine","(","in",")"),4321476). assertion_content_comment('oboGo_GlycineCAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","glycine","=","L-2-amino-3-oxobutanoate","+","CoA","+","H","(","+",")"),4249348). assertion_content_comment('oboGo_GlycineDehydrogenaseCyanideFormingactivity',s("Catalysis","of","the","reaction",":","glycine","+","2","A","=","HCN","+","CO2","+","2","AH2","."),4277969). assertion_content_comment('oboGo_GlycineGatedchloridechannelcomplex',s("A","protein","complex","that","forms","a","transmembrane","channel","through","which","chloride","ions","may","pass","in","response","to","glycine","binding","to","the","channel","complex","or","one","of","its","constituent","parts","."),4040784). assertion_content_comment('oboGo_GlycineGatedchlorideionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","glycine","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4333071). assertion_content_comment('oboGo_GlycineGlutamateThienylcyclohexylpiperidinebinding',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4254822). assertion_content_comment('oboGo_GlycineNAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","glycine","=","CoA","+","N-acylglycine","."),4377605). assertion_content_comment('oboGo_GlycineNBenzoyltransferaseactivity',s("Catalysis","of","the","reaction",":","benzoyl-CoA","+","glycine","=","N-benzoylglycine","+","CoA","+","H","(","+",")"),4377617). assertion_content_comment('oboGo_GlycineNCholoyltransferaseactivity',s("Catalysis","of","the","reaction",":","choloyl-CoA","+","glycine","=","CoA","+","glycocholate","."),4377674). assertion_content_comment('oboGo_GlycineNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","glycine","=","S-adenosyl-L-homocysteine","+","sarcosine","."),4258221). assertion_content_comment('oboGo_GlycineOxaloacetatetransaminaseactivity',s("Catalysis","of","the","reaction",":","glycine","+","oxaloacetate","=","L-aspartate","+","glyoxylate","."),4369151). assertion_content_comment('oboGo_GlycineReceptorAssociatedprotein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4217965). assertion_content_comment('oboGo_GlycineSarcosineNMethyltransferaseactivity',s("Catalysis","of","the","reactions",":","S-adenosyl-L-methionine","+","glycine","=","S-adenosyl-L-homocysteine","+","sarcosine",",","and","S-adenosyl-L-methionine","+","sarcosine","=","S-adenosyl-L-homocysteine","+","N",",","N-dimethylglycine","."),4342912). assertion_content_comment('oboGo_GlycineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","glycine","+","tRNA","(","Gly",")","=","AMP","+","diphosphate","+","glycyl-tRNA","(","Gly",")"),4199915). assertion_content_comment('oboGo_GlycineTrnaligasecomplex',s("A","multimeric","enzyme","complex","which",",","in","bacteria",",","is","usually","a","tetramer","of","two","alpha","and","two","beta","chains","and","in","eukaryotes",",","is","usually","a","homodimer",".","Functions","in","the","ligation","of","glycine","and","tRNA","(","Gly",")","to","form","glycyl-tRNA","(","Gly",")"),4259603). assertion_content_comment('oboGo_GlycogenSynthaseDphosphataseactivity',s("Catalysis","of","the","reaction",":","[","glycogen-synthase","D","]","+","H2O","=","[","glycogen-synthase","I","]","+","phosphate","."),4267316). assertion_content_comment('oboGo_Glycolipid2AlphaMannosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-mannosyl","residue","from","GDP-mannose","into","lipid-linked","oligosaccharide",",","forming","an","alpha-1",",","2-D-mannosyl-D-mannose","linkage","."),4207355). assertion_content_comment('oboGo_Glycolipid3AlphaMannosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-mannosyl","residue","from","GDP-mannose","into","lipid-linked","oligosaccharide",",","forming","an","alpha-1",",","3-D-mannosyl-D-mannose","linkage","."),4207332). assertion_content_comment('oboGo_Glycolipid6AlphaMannosyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","alpha-D-mannosyl","residue","from","GDP-mannose","into","lipid-linked","oligosaccharide",",","forming","an","alpha-1",",","6-D-mannosyl-D-mannose","linkage","."),4347791). assertion_content_comment('oboGo_GlycolipidTranslocatingactivity',s("Catalysis","of","the","movement","of","glycolipids","from","one","membrane","face","to","the","other","(","glycolipid","'","flippase","'","activity",")"),4359900). assertion_content_comment('oboGo_GlycopeptideAlphaNAcetylgalactosaminidaseactivity',s("Catalysis","of","the","reaction",":","D-galactosyl-3-","(","N-acetyl-alpha-D-galactosaminyl",")","-L-serine","+","H2O","=","D-galactosyl-3-N-acetyl-alpha-D-galactosamine","+","L-serine","."),4344715). assertion_content_comment('oboGo_Glycoprotein2BetaDXylosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl","}","-L-asparagine","+","UDP-alpha-D-xylose","=","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-","[","beta-D-xylosyl-","(","1-","&","gt",";","2",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl","}","-L-asparagine","+","H","(","+",")","+","UDP","."),4269179). assertion_content_comment('oboGo_Glycoprotein3AlphaLFucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl","}","-L-asparagine","+","GDP-L-fucose","=","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-","[","alpha-L-fucosyl-","(","1-","&","gt",";","3",")","]","-N-acetyl-beta-D-glucosaminyl","}","-L-asparagine","+","GDP","+","H","(","+",")"),4282632). assertion_content_comment('oboGo_Glycoprotein6AlphaLFucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl","}","-L-asparagine","+","GDP-L-fucose","=","N","(","4",")","-","{","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","3",")","-","[","N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","2",")","-alpha-D-mannosyl-","(","1-","&","gt",";","6",")","]","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl-","(","1-","&","gt",";","4",")","-","[","alpha-L-fucosyl-","(","1-","&","gt",";","6",")","]","-N-acetyl-beta-D-glucosaminyl","}","asparagine","+","GDP","+","H","(","+",")"),4253495). assertion_content_comment('oboGo_GlycoproteinEndo_Alpha_12_MannosidaseActivity',s("Catalysis","of","the","hydrolysis","of","the","terminal","alpha-glucosyl-","(","1",",","3",")","-mannosyl","unit","from","Glc-Man","(","9",")","-","(","GlcNAc",")","(","2",")","oligosaccharide","component","of","the","glycoprotein","produced","in","the","Golgi","membrane","."),4204529). assertion_content_comment('oboGo_GlycoproteinFucosylgalactosidealphaNAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-galactosamine","+","glycoprotein-alpha-L-fucosyl-","(","1",",","2",")","-D-galactose","=","UDP","+","glycoprotein-N-acetyl-alpha-D-galactosaminyl-","(","1",",","3",")","-","(","alpha-L-fucosyl-","(","1",",","2",")",")","-D-galactose","."),4208185). assertion_content_comment('oboGo_GlycoproteinNAcetylgalactosamine3BetaGalactosyltransferaseactivity',s("Catalysis","of","the","addition","of","a","galactosyl","residue","to","a","non-reducing","O-linked","N-acetylgalactosamine","residue","in","an","O-glycan","."),4303607). assertion_content_comment('oboGo_GlycoproteinNPalmitoyltransferaseactivity',s("Catalysis","of","the","reaction",":","palmitoyl-CoA","+","glycoprotein","=","CoA","+","N-palmitoylglycoprotein","."),4283422). assertion_content_comment('oboGo_GlycoproteinOFattyAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","palmitoyl-CoA","+","mucus","glycoprotein","=","CoA","+","O-palmitoylglycoprotein","."),4377651). assertion_content_comment('oboGo_GlycoproteinSpecificchaperoneactivity',s("OBSOLETE",".","Assists","in","the","correct",",","non-covalent","assembly","of","glycoproteins","in","vivo",",","but","is","not","a","component","of","the","assembled","structures","when","performing","its","normal","biological","function",".","Utilizes","a","lectin","site","as","a","means","to","associate","with","the","unfolded","glycoproteins","."),4192296). assertion_content_comment('oboGo_GlycosidePentosideHexuronide_Cationsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","(","glycoside",",","pentoside","or","hexuronide",")","(","out",")","+","monovalent","cation","(","out",")","=","(","glycoside",",","pentoside","or","hexuronide",")","(","in",")","+","monovalent","cation","(","in",")","The","cation","is","Na","+",",","Li","+","or","H","+"),4261133). assertion_content_comment('oboGo_GlycosylphosphatidylinositolDiacylglycerolLyaseactivity',s("Catalysis","of","the","reaction",":","6-","(","alpha-D-glucosaminyl",")","-1-phosphatidyl-1D-myo-inositol","=","1",",","2-diacyl-sn-glycerol","+","6-","(","alpha-D-glucosaminyl",")","-1D-myo-inositol","1",",","2-cyclic","phosphate","."),4368434). assertion_content_comment('oboGo_GlycosylphosphatidylinositolNAcetylglucosaminyltransferasegpiGntcomplex',s("An","enzyme","complex","that","catalyzes","the","transfer","of","GlcNAc","from","UDP-GlcNAc","to","an","acceptor","phosphatidylinositol",",","the","first","step","in","the","production","of","GPI","anchors","for","cell","surface","proteins",".","The","complex","contains","PIG-A",",","PIG-C",",","PIG-H",",","PIG-Q",",","PIG-P",",","and","DPM2","in","human",",","and","Eri1p",",","Gpi1p",",","Gpi2p",",","Gpi15p",",","Gpi19p",",","and","Spt14p","in","budding","yeast","."),4362301). assertion_content_comment('oboGo_GlycylpeptideNTetradecanoyltransferaseactivity',s("Catalysis","of","the","reaction",":","tetradecanoyl-CoA","+","glycyl-peptide","=","CoA","+","N-tetradecanoylglycyl-peptide","."),4207379). assertion_content_comment('oboGo_GlycylTrnaaminoacylation',s("The","process","of","coupling","glycine","to","glycyl-tRNA",",","catalyzed","by","glycyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179699). assertion_content_comment('oboGo_GlycyrrhizinateBetaGlucuronidaseactivity',s("Catalysis","of","the","reaction",":","glycyrrhizate","+","H","(","2",")","O","=","2-","(","beta-D-glucuronosyl",")","-D-glucuronate","+","glycyrrhetinate","."),4378652). assertion_content_comment('oboGo_GlyXcarboxypeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","peptidyl-Gly-Xaa","+","H2O","=","peptidyl-Gly","+","Xaa","."),4209830). assertion_content_comment('oboGo_GMP5Nucleotidaseactivity',s("Catalysis","of","the","reaction",":","5","'","-GMP","+","H2O","=","guanosine","+","phosphate","."),4258242). assertion_content_comment('oboGo_GMPSynthaseGlutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","ATP","+","xanthosine","5","'","-phosphate","+","L-glutamine","+","H2O","=","AMP","+","diphosphate","+","GMP","+","L-glutamate","."),4184463). assertion_content_comment('oboGo_GolgiAssociatedvesiclelumen',s("The","volume","enclosed","by","the","membrane","of","a","Golgi-associated","vesicle","."),4131947). assertion_content_comment('oboGo_GolgiAssociatedvesiclemembrane',s("The","lipid","bilayer","surrounding","a","vesicle","associated","with","the","Golgi","apparatus","."),4036038). assertion_content_comment('oboGo_GolgiAssociatedvesicle',s("Any","vesicle","associated","with","the","Golgi","complex","and","involved","in","mediating","transport","within","the","Golgi","or","between","the","Golgi","and","other","parts","of","the","cell","."),4035984). assertion_content_comment('oboGo_GolgiErtransportvesicle',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4221407). assertion_content_comment('oboGo_GolgiPlasmamembranetransportvesicle',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4221441). assertion_content_comment('oboGo_GolgiVacuoletransportvesicle',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4221452). assertion_content_comment('oboGo_GonadotrophinReleasinghormoneneuronalmigrationtothehypothalamus',s("The","directional","movement","of","a","gonadotrophin-releasing","hormone","producing","neuron","from","the","nasal","placode","to","the","hypothalamus","."),4051325). assertion_content_comment('oboGo_GonadotropinHormoneReleasinghormoneactivity',s("The","action","characteristic","of","gonadotropin","hormone-releasing","hormone","(","GnRH",")",",","any","of","a","family","of","decapeptide","amide","hormones","that","are","released","by","the","hypothalamus","in","response","to","neural","and/or","chemical","stimuli",".","In","at","least","mammals",",","upon","receptor","binding",",","GnRH","causes","the","release","of","follicle-stimulating","hormone","(","FSH",")","and","luteinizing","hormone","(","LH",")","by","the","anterior","pituitary","."),4216923). assertion_content_comment('oboGo_GonadotropinReleasinghormonebinding',s("Interacting","selectively","and","non-covalently","with","gonadotropin-releasing","hormone",",","a","peptide","hormone","responsible","for","the","release","of","follicle-stimulating","hormone","(","FSH",")","and","luteinizing","hormone","(","LH",")","from","the","anterior","pituitary","and","it","is","synthesized","and","released","by","the","hypothalamus","."),4286559). assertion_content_comment('oboGo_GonadotropinReleasinghormonereceptoractivity',s("Combining","with","gonadotropin-releasing","hormone","to","initiate","a","change","in","cell","activity","."),4197974). assertion_content_comment('oboGo_GonadotropinReleasinghormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","receptor","for","gonadotropin-releasing","hormone",",","a","peptide","hormone","that","is","synthesized","and","released","by","the","hypothalamus","and","is","responsible","for","the","release","of","follicle-stimulating","hormone","(","FSH",")","and","luteinizing","hormone","(","LH",")","from","the","anterior","pituitary","."),4321939). assertion_content_comment('oboGo_GoodpastureAntigenBindingproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","Goodpasture","antigen-binding","protein","=","ADP","+","Goodpasture","antigen-binding","phosphoprotein","."),4343622). assertion_content_comment('oboGo_GP40Likereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383949). assertion_content_comment('oboGo_GPIAnchorBinding_8',s("Interacting","selectively","and","non-covalently","with","any","glycosylphosphatidylinositol","anchor",".","GPI","anchors","serve","to","attach","membrane","proteins","to","the","lipid","bilayer","of","cell","membranes","."),4359648). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNAlanylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-alanine","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","an","alanyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280468). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNAsparaginylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-asparagine","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","asparaginyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280683). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNAspartylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-aspartic","acid","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","aspartyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280669). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNCysteinylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-cysteine","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","cysteinyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280655). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNGlycylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-glycine","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","glycyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280641). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNSerylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-serine","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","seryl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4280627). assertion_content_comment('oboGo_GPIAnchorBiosyntheticProcessViaNThreonylGlycosylphosphatidylinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-threonyl","ethanolamide-linked","glycosylphosphatidylinositol","(","GPI",")","anchor","following","hydrolysis","of","a","threonyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4266451). assertion_content_comment('oboGo_GPIAnchoredmembraneBoundreceptor',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4296742). assertion_content_comment('oboGo_GPIAnchortransamidaseactivity',s("Catalysis","of","the","formation","of","the","linkage","between","a","protein","and","a","glycosylphosphatidylinositol","anchor",".","The","reaction","probably","occurs","by","subjecting","a","peptide","bond","to","nucleophilic","attack","by","the","amino","group","of","ethanolamine-GPI",",","transferring","the","protein","from","a","signal","peptide","to","the","GPI","anchor","."),4185604). assertion_content_comment('oboGo_GPIAnchortransamidasecomplex',s("An","enzyme","complex","which","in","humans","and","yeast","consists","of","at","least","five","proteins",";","for","example",",","the","complex","contains","GAA1",",","GPI8",",","PIG-S",",","PIG-U",",","and","PIG-T","in","human",",","and","Gaa1p",",","Gab1p",",","Gpi8p",",","Gpi16p",",","and","Gpi17p","in","yeast",".","Catalyzes","the","posttranslational","attachment","of","the","carboxyl-terminus","of","a","precursor","protein","to","a","GPI-anchor","."),4077364). assertion_content_comment('oboGo_GPILinkedephrinreceptoractivity',s("Combining","with","a","GPI-anchored","ephrin","to","initiate","a","change","in","cell","activity","."),4213864). assertion_content_comment('oboGo_GPILinkedephrin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4214356). assertion_content_comment('oboGo_GPR37EndothelinBLikereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383553). assertion_content_comment('oboGo_GProteinactivatedinwardrectifierpotassiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","potassium","ion","by","an","inwardly-rectifying","voltage-gated","channel",",","where","the","inward","rectification","is","due","to","a","voltage-dependent","block","of","the","channel","pore","by","a","G","protein",".","An","inwardly","rectifying","current-voltage","relation","is","one","where","at","any","given","driving","force","the","inward","flow","of","K","+","ions","exceeds","the","outward","flow","for","the","opposite","driving","force","."),4291805). assertion_content_comment('oboGo_GProteinalpha13Synembrincomplex',s("A","protein","complex","formed","by","the","association","of","the","guanine","nucleotide","exchange","factor","synembrin","with","the","alpha","(","13",")","subunit","of","a","heterotrimeric","G","protein","."),4164740). assertion_content_comment('oboGo_GProteinalphai1Synembrincomplex',s("A","protein","complex","formed","by","the","association","of","the","guanine","nucleotide","exchange","factor","synembrin","with","the","alpha","(","i",")","1","subunit","of","a","heterotrimeric","G","protein","."),4164873). assertion_content_comment('oboGo_GProteinalphaoSynembrincomplex',s("A","protein","complex","formed","by","the","association","of","the","guanine","nucleotide","exchange","factor","synembrin","with","the","alpha","(","o",")","subunit","of","a","heterotrimeric","G","protein","."),4164885). assertion_content_comment('oboGo_GProteinalphaqSynembrincomplex',s("A","protein","complex","formed","by","the","association","of","the","guanine","nucleotide","exchange","factor","synembrin","with","the","alpha","(","q",")","subunit","of","a","heterotrimeric","G","protein","."),4164897). assertion_content_comment('oboGo_GProteinalphaSubunitbinding',s("Interacting","selectively","and","non-covalently","with","a","G-protein","alpha","subunit",".","The","alpha","subunit","binds","a","guanine","nucleotide","."),4384190). assertion_content_comment('oboGo_GProteinbetagammaBtkcomplex',s("A","protein","complex","formed","by","the","association","of","the","Bruton","tyrosine","protein","kinase","Btk",",","which","is","implicated","in","mammalian","X-linked","immunodeficiencies",",","with","the","beta","and","gamma","subunits","of","a","heterotrimeric","G","protein","."),4175373). assertion_content_comment('oboGo_G_ProteinBetaGamma_Raf_1Complex',s("A","protein","complex","formed","by","the","association","of","the","serine-threonine","protein","kinase","Raf-1","with","the","beta","and","gamma","subunits","of","a","heterotrimeric","G","protein","."),4175551). assertion_content_comment('oboGo_GProteinbetagammaSubunitcomplexbinding',s("Interacting","selectively","and","non-covalently","with","a","complex","of","G-protein","beta/gamma","subunits","."),4322432). assertion_content_comment('oboGo_GProteinbetagammaSubunitcomplex',s("The","heterodimer","formed","by","the","beta","and","gamma","subunits","of","a","heterotrimeric","G","protein",",","which","dissociates","from","the","alpha","subunit","upon","guanine","nuclotide","exchange","."),4322401). assertion_content_comment('oboGo_GProteinbetaSubunitbinding',s("Interacting","selectively","and","non-covalently","with","a","G-protein","beta","subunit","."),4322422). assertion_content_comment('oboGo_GProteinchemoattractantreceptoractivity',s("Combining","with","a","chemoattractant","peptide","to","initiate","a","G-protein","mediated","change","in","cell","activity","."),4197845). assertion_content_comment('oboGo_GProteincoupledacetylcholinereceptoractivity',s("Combining","with","acetylcholine","to","initiate","a","change","in","cell","activity","via","activation","of","a","G","protein","."),4198863). assertion_content_comment('oboGo_GProteincoupledaminereceptoractivity',s("A","receptor","that","binds","an","extracellular","amine","and","transmits","the","signal","to","a","heterotrimeric","G-protein","complex",".","These","receptors","are","characteristically","seven-transmembrane","receptors","and","are","made","up","of","hetero-","or","homodimers","."),4197805). assertion_content_comment('oboGo_GProteincoupledcytokininreceptoractivity',s("Combining","with","a","cytokinin","to","initiate","a","change","in","cell","activity",".","The","receptor","is","G-protein","coupled","."),4384038). assertion_content_comment('oboGo_GProteincoupledphotoreceptoractivity',s("A","G-protein","coupled","receptor","that","responds","to","incidental","electromagnetic","radiation",",","particularly","visible","light","."),4246990). assertion_content_comment('oboGo_GProteincoupledpurinergicnucleotidereceptorsignalingpathway',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","receptor","binding","to","an","extracellular","purine","nucleotide","and","transmitting","the","signal","to","a","heterotrimeric","G-protein","complex","to","initiate","a","change","in","cell","activity","."),4378264). assertion_content_comment('oboGo_GProteincoupledpurinergicreceptorsignalingpathway',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","receptor","binding","to","an","extracellular","purine","or","purine","derivative","and","transmitting","the","signal","to","a","heterotrimeric","G-protein","complex","to","initiate","a","change","in","cell","activity","."),4108427). assertion_content_comment('oboGo_GProteincoupledreceptoractivity',s("A","receptor","that","binds","an","extracellular","ligand","and","transmits","the","signal","to","a","heterotrimeric","G-protein","complex",".","These","receptors","are","characteristically","seven-transmembrane","receptors","and","are","made","up","of","hetero-","or","homodimers","."),4071561). assertion_content_comment('oboGo_GProteinCoupledreceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","G-protein-coupled","receptor","."),4170585). assertion_content_comment('oboGo_GProteincoupledreceptorinternalization',s("The","process","that","results","in","the","uptake","of","a","G-protein","coupled","receptor","into","an","endocytic","vesicle","."),3991251). assertion_content_comment('oboGo_GProteincoupledreceptorkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","G-protein","coupled","receptor","=","ADP","+","G-protein","coupled","receptor","phosphate","."),4200713). assertion_content_comment('oboGo_GProteincoupledreceptorproteinsignalingpathway',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand","."),3973451). assertion_content_comment('oboGo_GProteindissociation',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4236230). assertion_content_comment('oboGo_GProteingammaSubunitbinding',s("Interacting","selectively","and","non-covalently","with","a","G-protein","gamma","subunit","."),4322412). assertion_content_comment('oboGo_GProteinreceptor45Likereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383864). assertion_content_comment('oboGo_GProteinsignalingcoupledtocampnucleotidesecondmessenger',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","followed","by","modulation","of","adenylyl","cyclase","activity","and","a","subsequent","change","in","the","concentration","of","cyclic","AMP","."),4027458). assertion_content_comment('oboGo_GProteinsignalingcoupledtocgmpnucleotidesecondmessenger',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","followed","by","activation","of","guanylyl","cyclase","and","a","subsequent","increase","in","the","concentration","of","cyclic","GMP","."),4235969). assertion_content_comment('oboGo_GProteinsignalingcoupledtocyclicnucleotidesecondmessenger',s("The","series","of","molecular","signals","generated","as","a","consequence","of","a","G-protein","coupled","receptor","binding","to","its","physiological","ligand",",","followed","by","modulation","of","a","nucleotide","cyclase","activity","and","a","subsequent","change","in","the","concentration","of","a","cyclic","nucleotide","."),4027431). assertion_content_comment('oboGo_GProteinsignalingcoupledtos1psecondmessengersphingosinekinaseactivating',s("A","G-protein","coupled","signaling","pathway","that","results","in","the","activation","of","sphingosine","kinase",",","causing","an","increase","in","cellular","levels","of","sphingosine-1-phosphate","."),4383347). assertion_content_comment('oboGo_GQuadruplexdnabinding',s("Interacting","selectively","and","non-covalently","with","G-quadruplex","DNA","structures",",","in","which","groups","of","four","guanines","adopt","a","flat",",","cyclic","Hoogsteen","hydrogen-bonding","arrangement","known","as","a","guanine","tetrad",".","The","stacking","of","guanine","tetrads","results","in","G-quadruplex","DNA","structures",".","G-quadruplex","DNA","can","form","under","physiological","conditions","from","some","G-rich","sequences",",","such","as","those","found","in","telomeres",",","immunoglobulin","switch","regions",",","gene","promoters",",","fragile","X","repeats",",","and","the","dimerization","domain","in","the","human","immunodeficiency","virus","(","HIV",")","genome","."),4282294). assertion_content_comment('oboGo_GQuadruplexdnaformation',s("A","DNA","metabolic","process","that","results","in","the","formation","of","G-quadruplex","DNA","structures",",","in","which","groups","of","four","guanines","adopt","a","flat",",","cyclic","Hoogsteen","hydrogen-bonding","arrangement","known","as","a","guanine","tetrad","or","G-quartet",".","The","stacking","of","several","layers","of","G-quartets","forms","G-quadruplexes",",","in","which","one","or","more","DNA","single","strands","are","assembled","in","parallel","and/or","antiparallel",",","with","interactions","that","can","be","either","intra-","or","intermolecular","in","nature","."),4168195). assertion_content_comment('oboGo_GQuadruplexrnabinding',s("Interacting","selectively","and","non-covalently","with","G-quadruplex","RNA","structures",",","in","which","groups","of","four","guanines","adopt","a","flat",",","cyclic","hydrogen-bonding","arrangement","known","as","a","guanine","tetrad","."),4375323). assertion_content_comment('oboGo_GramNegativeantibacterialpeptideactivity',s("OBSOLETE",".","Inhibits","the","growth","of",",","or","directly","kills",",","Gram-negative","bacterial","cells","."),4255875). assertion_content_comment('oboGo_GramNegativebacterialcellsurfacebinding',s("Interacting","selectively","and","non-covalently","with","any","component","on","the","surface","of","a","Gram-negative","bacterial","cell","."),4285274). assertion_content_comment('oboGo_GramNegativeBacteriumTypecelloutermembraneassembly',s("The","assembly","of","an","outer","membrane","of","the","type","formed","in","Gram-negative","bacteria",".","This","membrane","is","enriched","in","polysaccharide","and","protein",",","and","the","outer","leaflet","of","the","membrane","contains","specific","lipopolysaccharide","structures","."),4093073). assertion_content_comment('oboGo_GramNegativeBacteriumTypecellwallbiogenesis',s("A","cellular","process","that","results","in","the","biosynthesis","of","constituent","macromolecules",",","assembly",",","and","arrangement","of","constituent","parts","of","a","cell","wall","of","the","type","found","in","Gram-negative","bacteria",".","The","cell","wall","is","the","rigid","or","semi-rigid","envelope","lying","outside","the","cell","membrane","."),4317633). assertion_content_comment('oboGo_GramNegativeBacteriumTypecellwall',s("The","peptidoglycan","layer","of","the","Gram-negative","cell","envelope",".","In","Gram-negative","cells","the","peptidoglycan","is","relatively","thin","(","1-2nm",")","and","is","linked","to","the","outer","membrane","by","lipoproteins",".","In","Gram-negative","cells","the","peptidoglycan","is","too","thin","to","retain","the","primary","stain","in","the","Gram","staining","procedure","and","therefore","cells","appear","red","after","Gram","stain","."),4023813). assertion_content_comment('oboGo_GramPositiveantibacterialpeptideactivity',s("OBSOLETE",".","Inhibits","the","growth","of",",","or","directly","kills",",","Gram-positive","bacterial","cells","."),4255855). assertion_content_comment('oboGo_GramPositivebacterialcellsurfacebinding',s("Interacting","selectively","and","non-covalently","with","any","component","on","the","surface","of","a","Gram-positive","bacterium","."),4285289). assertion_content_comment('oboGo_GramPositiveBacteriumTypecellwall',s("A","layer","of","peptidoglycan","found","outside","of","the","cytoplasmic","membrane",".","The","peptidoglycan","is","relatively","thick","(","20-80nm",")","and","retains","the","primary","stain","of","the","Gram","procedure",",","thus","cells","appear","blue","after","Gram","stain",".","The","cell","walls","often","contain","teichoic","acids","(","acidic","anionic","polysaccharides",")","bound","to","the","peptidoglycan",".","Examples","of","this","component","are","found","in","Gram-positive","bacteria","."),4257255). assertion_content_comment('oboGo_GranulocyteColonyStimulatingfactorbinding',s("Interacting","selectively","and","non-covalently","with","granulocyte","colony-stimulating","factor",",","G-CSF","."),4183174). assertion_content_comment('oboGo_GranulocyteColonyStimulatingfactorproduction',s("The","appearance","of","granulocyte","colony-stimulating","factor","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4129086). assertion_content_comment('oboGo_GranulocyteColonyStimulatingfactorreceptoractivity',s("Combining","with","granulocyte","colony-stimulating","factor","to","initiate","a","change","in","cell","activity","."),4198332). assertion_content_comment('oboGo_GranulocyteColonyStimulatingfactorreceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","granulocyte","colony-stimulating","factor","receptor","."),4214553). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","granulocyte","macrophage","colony-stimulating","factor",",","cytokines","that","act","in","hemopoiesis","by","controlling","the","production",",","differentiation",",","and","function","of","two","related","white","cell","populations",",","granulocytes","and","monocytes-macrophages","."),4079279). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorcomplexbinding',s("Interacting","selectively","and","non-covalently","with","the","granulocyte","macrophage","colony-stimulating","factor","complex","."),4306268). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorproduction',s("The","appearance","of","granulocyte","macrophage","colony-stimulating","factor","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067016). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorreceptoractivity',s("Combining","with","granulocyte","macrophage","colony-stimulating","factor","to","initiate","a","change","in","cell","activity","."),4198413). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorreceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","granulocyte","macrophage","colony-stimulating","factor","receptor","."),4214614). assertion_content_comment('oboGo_GranulocyteMacrophageColonyStimulatingfactorreceptorcomplex',s("The","heterodimeric","receptor","for","granulocyte","macrophage","colony-stimulating","factor","."),4046670). assertion_content_comment('oboGo_Grb2Egfrcomplex',s("A","protein","complex","that","contains","the","epidermal","growth","factor","receptor","(","EGFR",")","and","Grb2",",","and","is","involved","in","linking","EGFR","activation","to","the","p21-Ras","pathway","."),4175314). assertion_content_comment('oboGo_Grb2Shccomplex',s("A","protein","complex","that","contains","Grb2","and","the","adaptor","protein","Shc",",","and","is","involved","in","linking","epidermal","growth","factor","receptor","(","EGFR",")","activation","to","the","p21-Ras","pathway","."),4175303). assertion_content_comment('oboGo_Grb2_SHP_2Complex',s("A","protein","complex","that","contains","the","receptor","adaptor","proteins","Grb2","and","SHP-2",",","and","is","involved","signaling","via","the","PDGFR","signaling","pathway","."),4176623). assertion_content_comment('oboGo_Grb2Soscomplex',s("A","protein","complex","that","contains","Grb2","and","the","guanine","nucleotide","exchange","factor","Sos","(","or","an","ortholog","thereof",",","such","as","mSos1",")",",","and","is","involved","in","linking","EGFR","activation","to","the","p21-Ras","pathway","."),4177160). assertion_content_comment('oboGo_GreenSensitiveopsin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4297184). assertion_content_comment('oboGo_GrowthHormoneReleasinghormoneactivity',s("The","action","characteristic","of","growth","hormone-releasing","hormone",",","any","of","a","family","of","peptide","hormones","that","act","on","the","anterior","pituitary","to","stimulate","the","secretion","of","growth","hormone","and","exert","a","trophic","effect","on","the","gland","."),4305928). assertion_content_comment('oboGo_GrowthHormoneReleasinghormonereceptoractivity',s("Combining","with","growth","hormone-releasing","hormone","to","initiate","a","change","in","cell","activity","."),4305190). assertion_content_comment('oboGo_GrowthHormoneReleasinghormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","growth","hormone-releasing","hormone","receptor","."),4322789). assertion_content_comment('oboGo_GrowthHormoneSecretagogueLikereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383603). assertion_content_comment('oboGo_GrowthOfAGermariumDerivedeggchamber',s("Growth","of","the","egg","chamber","between","the","time","it","leaves","the","germarium","and","the","onset","of","vitellogenesis",".","During","this","time","both","nurse","cells","and","the","oocyte","undergo","developmental","changes","including","nuclear","organization","and","cytoplasmic","growth",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4016919). assertion_content_comment('oboGo_GSIAnchorBiosyntheticProcessViaNGlycylGlycosylsphingolipidinositolethanolamine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","C-terminal","peptidyl-glycine","ethanolamide-linked","glycosylsphingolipidinositol","(","GSI",")","anchor","following","hydrolysis","of","a","glycyl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4266496). assertion_content_comment('oboGo_GSIAnchorBiosyntheticProcessViaNSerylGlycosylsphingolipidinositolethanolamine',s("The","formation","of","a","C-terminal","peptidyl-serine","ethanolamide-linked","glycosylsphingolipidinositol","(","GSI",")","anchor","following","hydrolysis","of","a","seryl-peptide","bond","in","the","carboxy-terminal","region","of","a","membrane-associated","protein","."),4281033). assertion_content_comment('oboGo_GTPDependenthelicaseactivity',s("Catalysis","of","the","reaction",":","GTP","+","H2O","=","GDP","+","phosphate",",","to","drive","the","unwinding","of","a","DNA","or","RNA","helix","."),4180590). assertion_content_comment('oboGo_GTPDependentpolydeoxyribonucleotide5HydroxylKinaseactivity',s("Catalysis","of","the","reaction",":","GTP","+","5","'","-dephospho-DNA","=","GDP","+","5","'","-phospho-DNA","."),4281007). assertion_content_comment('oboGo_GTPDependentpolynucleotidekinaseactivity',s("Catalysis","of","the","reaction",":","GTP","+","5","'","-dephosphopolynucleotide","=","GDP","+","5","'","-phosphopolynucleotide",".","The","polynucleotide","may","be","DNA","or","RNA","."),4281003). assertion_content_comment('oboGo_GTPDependentpolyribonucleotide5HydroxylKinaseactivity',s("Catalysis","of","the","reaction",":","GTP","+","5","'","-dephospho-RNA","=","GDP","+","5","'","-phospho-RNA","."),4281059). assertion_content_comment('oboGo_GTPDependentproteinbinding',s("Interacting","selectively","and","non-covalently","with","any","protein","or","protein","complex","(","a","complex","of","two","or","more","proteins","that","may","include","other","nonprotein","molecules",")","using","energy","from","the","hydrolysis","of","GTP","."),4308791). assertion_content_comment('oboGo_GTPDependentproteinkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","protein","serine/threonine","=","ADP","+","protein","serine/threonine","phosphate",",","dependent","on","the","presence","of","GTP","."),4359754). assertion_content_comment('oboGo_GTPRalbinding',s("Interacting","selectively","and","non-covalently","with","the","GTP-bound","form","of","the","Ral","protein","."),4348508). assertion_content_comment('oboGo_GTPRhobinding',s("Interacting","selectively","and","non-covalently","with","the","GTP-bound","form","of","the","Rho","protein","."),4268303). assertion_content_comment('oboGo_GUACodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GUA","codon","."),4339480). assertion_content_comment('oboGo_GuanidinoacetateNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","guanidinoacetate","=","S-adenosyl-L-homocysteine","+","creatine","+","H","(","+",")"),4308905). assertion_content_comment('oboGo_Guanidinodeoxy_Scyllo_Inositol_4_PhosphataseActivity',s("Catalysis","of","the","reaction",":","1-guanidino-1-deoxy-scyllo-inositol","4-phosphate","+","H","(","2",")","O","=","1-guanidino-1-deoxy-scyllo-inositol","+","phosphate","."),4368634). assertion_content_comment('oboGo_GuanineTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","guanine","(","out",")","=","ADP","+","phosphate","+","guanine","(","in",")"),4252759). assertion_content_comment('oboGo_Guanosine_35_BisDiphosphate3_DiphosphataseActivity',s("Catalysis","of","the","reaction",":","guanosine","3","'",",","5","'","-bis","(","diphosphate",")","+","H2O","=","guanosine","5","'","-diphosphate","+","diphosphate","."),4249399). assertion_content_comment('oboGo_Guanosine_5_Triphosphate3_DiphosphateDiphosphataseActivity',s("Catalysis","of","the","reaction",":","guanosine","5","'","-triphosphate",",","3","'","-diphosphate","+","H2O","=","guanosine","5","'","-diphosphate",",","3","'","-diphosphate","+","phosphate","."),4249417). assertion_content_comment('oboGo_GuanosineDiphosphataseactivity',s("Catalysis","of","the","reaction",":","GDP","+","H2O","=","GMP","+","phosphate","."),4208156). assertion_content_comment('oboGo_GuanosineTriphosphateguanylyltransferaseactivity',s("Catalysis","of","the","reaction",":","2","GTP","=","P","(","1",")",",","P","(","4",")","-bis","(","5","'","-guanosyl",")","tetraphosphate","+","diphosphate","+","H","(","+",")"),4367975). assertion_content_comment('oboGo_GuanylNucleotideexchangefactoractivity',s("Stimulates","the","exchange","of","guanyl","nucleotides","associated","with","a","GTPase",".","Under","normal","cellular","physiological","conditions",",","the","concentration","of","GTP","is","higher","than","that","of","GDP",",","favoring","the","replacement","of","GDP","by","GTP","in","association","with","the","GTPase","."),4215241). assertion_content_comment('oboGo_GuanylNucleotideexchangefactoradaptoractivity',s("The","binding","activity","of","a","molecule","that","brings","together","a","guanyl-nucleotide","exchange","factor","and","one","or","more","other","molecules",",","permitting","them","to","function","in","a","coordinated","way","."),4215219). assertion_content_comment('oboGo_GuanylNucleotideexchangefactorcomplex',s("A","protein","complex","that","stimulates","the","exchange","of","guanyl","nucleotides","associated","with","a","GTPase","."),4330283). assertion_content_comment('oboGo_GUCCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GUC","codon","."),4339468). assertion_content_comment('oboGo_GUGCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GUG","codon","."),4339492). assertion_content_comment('oboGo_GUMismatchSpecificuracilDnaglycosylaseactivity',s("Catalysis","of","the","removal","of","uracil","from","a","U","*","G","mispair","by","the","cleavage","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","uracil","and","leaves","an","apyrimidinic","(","AP",")","site","."),4325889). assertion_content_comment('oboGo_GUUCodonAminoacidadaptoractivity',s("A","triplet","codon-amino","acid","adaptor","activity","that","recognizes","a","GUU","codon","."),4339411). assertion_content_comment('oboGo_HAC1Typeintronsplicesiterecognitionandcleavage',s("The","process","in","which","the","tertiary","structure","of","a","HAC1","type","intron","is","recognized",",","and","the","endonucleolytic","cleavage","of","the","RNA","at","both","the","5","'","and","3","'","splice","sites","occurs","."),4133838). assertion_content_comment('oboGo_HalimadienylDiphosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","geranylgeranyl","diphosphate","=","halima-5","(","6",")",",","13-dien-15-yl","diphosphate","."),4375622). assertion_content_comment('oboGo_HalohydrinHydrogenHalideLyaseaactivity',s("Catalysis","of","the","elimination","of","HCl","from","a","chloro-","or","bromopropanol",",","yielding","an","epoxypropane","."),4273475). assertion_content_comment('oboGo_HalohydrinHydrogenHalideLyaseactivity',s("Catalysis","of","the","reaction",":","a","halohydrin","=","an","epoxide","+","a","hydrogen","halide","."),4237830). assertion_content_comment('oboGo_HalohydrinHydrogenHalideLyasebactivity',s("Catalysis","of","the","elimination","of","HCl","from","a","chloropropanol",",","yielding","an","epoxypropane","."),4273572). assertion_content_comment('oboGo_HaptoglobinHemoglobincomplex',s("A","protein","complex","formed","by","the","stable","binding","of","a","haptoglobin","to","hemoglobin","."),4324392). assertion_content_comment('oboGo_HeatShockMediatedpolytenechromosomepuffing',s("The","decondensing","(","loosening",")","and","swelling","of","the","chromosomal","sites","of","heat","shock","genes","on","polytene","chromosomes","in","response","to","a","heat","shock","stimulus","."),4381639). assertion_content_comment('oboGo_HeavyMetalExportingatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","heavy","metal","ion","(","in",")","+","ATP","+","H2O","=","heavy","metal","ion","(","out",")","+","ADP","+","phosphate","."),4212911). assertion_content_comment('oboGo_HemeCopperterminaloxidaseactivity',s("Catalysis","of","the","four-electron","reduction","of","dioxygen","(","O2",")","to","water",",","coupled","to","generation","of","a","proton","electrochemical","gradient","across","a","membrane","."),4211560). assertion_content_comment('oboGo_HemeTransportingatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","+","heme","(","in",")","=","ADP","+","phosphate","+","heme","(","out",")"),4291978). assertion_content_comment('oboGo_HeparanAlphaGlucosaminidenAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","heparan","alpha-D-glucosaminide","=","CoA","+","heparan","N-acetyl-alpha-D-glucosaminide","."),4296800). assertion_content_comment('oboGo_HeparanSulfate2OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","heparan","sulfate","=","adenosine","3","'",",","5","'","-bisphosphate","+","heparan","sulfate","2-O-sulfate",";","results","in","2-O-sulfation","of","iduronic","acid","residues","in","heparan","sulfate","."),4208093). assertion_content_comment('oboGo_HeparanSulfate6OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","heparan","sulfate","=","adenosine","3","'",",","5","'","-bisphosphate","+","heparan","sulfate","6-O-sulfate",";","results","in","6-O-sulfation","of","glucosamine","residues","in","heparan","sulfate","."),4267740). assertion_content_comment('oboGo_HeparanSulfateGlucosamine3Sulfotransferase1activity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenylyl","sulfate","+","[","heparan","sulfate","]","-glucosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","[","heparan","sulfate","]","-glucosamine","3-sulfate",".","The","[","heparan","sulfate","]","-glucosamine","3-sulfate","has","a","substrate","consensus","sequence","of","Glc","(","N2S","&","gt",";","NAc",")","+","/-6S","GlcA","GlcN2S","*","+","/-6S","GlcA","&","gt",";","IdoA","+","/-2S","Glc","(","N2S/NAc",")","+","/-6S","."),4254137). assertion_content_comment('oboGo_HeparanSulfateGlucosamine3Sulfotransferase2activity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenylyl","sulfate","+","[","heparan","sulfate","]","-glucosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","[","heparan","sulfate","]","-glucosamine","3-sulfate",";","modifies","selected","glucosamine","residues","preceded","by","GlcA2S","."),4343543). assertion_content_comment('oboGo_HeparanSulfateGlucosamine3Sulfotransferase3activity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenylyl","sulfate","+","[","heparan","sulfate","]","-glucosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","[","heparan","sulfate","]","-glucosamine","3-sulfate","."),4343592). assertion_content_comment('oboGo_HeparanSulfateGlucosaminenSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenylyl","sulfate","+","[","heparan","sulfate","]","-glucosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","[","heparan","sulfate","]","-N-sulfoglucosamine","."),4296839). assertion_content_comment('oboGo_HeparanSulfateNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","heparan","sulfate","=","UDP","+","(","N-acetyl-D-glucosaminyl",")","-heparan","sulfate","."),4312860). assertion_content_comment('oboGo_HeparinSulfatelyaseactivity',s("Catalysis","of","the","elimination","of","sulfate",";","appears","to","act","on","linkages","between","N-acetyl-D-glucosamine","and","uronate",".","Product","is","an","unsaturated","sugar","."),4296785). assertion_content_comment('oboGo_HeparosanNSulfateGlucuronate5Epimeraseactivity',s("Catalysis","of","the","reaction",":","heparosan-N-sulfate","D-glucuronate","=","heparosan-N-sulfate","L-iduronate","."),4369477). assertion_content_comment('oboGo_HepoxilinEpoxidehydrolaseactivity',s("Catalysis","of","the","reaction",":","(","5Z",",","9E",",","14Z",")","-","(","8x",",","11R",",","12S",")","-11",",","12-epoxy-8-hydroxyicosa-5",",","9",",","14-trienoate","+","H2O","=","(","5Z",",","9E",",","14Z",")","-","(","8x",",","11x",",","12S",")","-8",",","11",",","12-trihydroxyicosa-5",",","9",",","14-trienoate","."),4378676). assertion_content_comment('oboGo_Heptose1Phosphateadenyltransferaseactivity',s("Catalysis","of","the","reaction",":","D-beta-D-heptose-1-phosphate","+","ATP","=","ADP-D-glycero-D-manno-heptose","."),4252156). assertion_content_comment('oboGo_Heptose7Phosphatekinaseactivity',s("Catalysis","of","the","reaction",":","D-alpha",",","beta-D-heptose-7-phosphate","+","ATP","=","D-beta-D-heptose-1",",","7-bisphosphate","+","ADP","."),4252144). assertion_content_comment('oboGo_HermaphroditeGermLinesexdetermination',s("The","determination","of","sex","and","sexual","phenotype","in","the","germ","line","of","a","hermaphrodite","."),4232556). assertion_content_comment('oboGo_HeteroduplexFormationInvolvedInDoubleStrandbreakrepairviasynthesisDependentstrandannealing',s("The","formation","of","a","stable","duplex","DNA","that","contains","one","strand","from","each","of","the","two","recombining","DNA","molecules","resulting","in","the","error-free","repair","of","a","double-strand","break","without","the","exchange","of","adjacent","sequences","."),4026796). assertion_content_comment('oboGo_HeteroduplexFormationInvolvedInGeneConversionAtMatingTypelocus',s("The","formation","of","a","stable","duplex","DNA","that","contains","one","strand","from","each","of","the","two","recombining","DNA","molecules","resulting","in","the","conversion","of","the","mating-type","locus","from","one","allele","to","another","."),4026786). assertion_content_comment('oboGo_HeteroglycanAlphaMannosyltransferaseactivity',s("Catalysis","of","the","reactions",":","heteroglycan","+","GDP-mannose","=","1",",","2-alpha-D-mannosylheteroglycan","+","GDP",",","and","heteroglycan","+","GDP-mannose","=","1",",","3-alpha-D-mannosylheteroglycan","+","GDP","."),4367076). assertion_content_comment('oboGo_HeterophilicCellCelladhesion',s("The","attachment","of","an","adhesion","molecule","in","one","cell","to","a","nonidentical","adhesion","molecule","in","an","adjacent","cell","."),3977551). assertion_content_comment('oboGo_HeterotrimericGProteinbinding',s("Interacting","selectively","and","non-covalently","with","a","heterotrimeric","G-protein","."),4337678). assertion_content_comment('oboGo_HeterotrimericGProteincomplexcycle',s("The","series","of","molecular","events","that","generate","a","signal","through","the","activation","of","G-protein","subunits","and","recycling","of","these","subunits","."),4056828). assertion_content_comment('oboGo_HeterotrimericGProteincomplex',s("Any","of","a","family","of","heterotrimeric","GTP-binding","and","hydrolyzing","proteins",";","they","belong","to","a","superfamily","of","GTPases","that","includes","monomeric","proteins","such","as","EF-Tu","and","RAS",".","Heterotrimeric","G-proteins","consist","of","three","subunits",";","the","alpha","subunit","contains","the","guanine","nucleotide","binding","site","and","possesses","GTPase","activity",";","the","beta","and","gamma","subunits","are","tightly","associated","and","function","as","a","beta-gamma","heterodimer",";","extrinsic","plasma","membrane","proteins","(","cytoplasmic","face",")","that","function","as","a","complex","to","transduce","signals","from","G-protein","coupled","receptors","to","an","effector","protein","."),4185563). assertion_content_comment('oboGo_HeterotrimericGProteingtpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","GTP","+","H2O","=","GDP","+","phosphate",".","GTP-hydrolyzing","enzymes",",","where","GTP","and","GDP","alternate","in","binding",".","Includes","stimulatory","and","inhibitory","G-proteins","such","as","Gs",",","Gi",",","Go","and","Golf",",","targeting","adenylate","cyclase","and/or","potassium","ion","and","calcium","ion","channels",";","Gq","stimulating","phospholipase","C",";","transducin","activating","cGMP","phosphodiesterase",";","gustducin","activating","cAMP","phosphodiesterase","."),4185570). assertion_content_comment('oboGo_HeterotrimericGProteingtpasealphaSubunit',s("OBSOLETE",".","Subunit","of","a","heterotrimeric","G-protein","GTPase","that","contains","the","guanine","nucleotide","binding","site","and","possesses","GTPase","activity","."),4346601). assertion_content_comment('oboGo_HeterotrimericGProteingtpasebetaSubunit',s("OBSOLETE",".","Subunit","of","a","heterotrimeric","G-protein","GTPase",";","associates","tightly","with","the","gamma","subunit","."),4346589). assertion_content_comment('oboGo_HeterotrimericGProteingtpasegammaSubunit',s("OBSOLETE",".","Smallest","subunit","of","a","heterotrimeric","G-protein","GTPase",";","associates","tightly","with","the","beta","subunit","."),4346613). assertion_content_comment('oboGo_HeterotrimericGProtein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4215019). assertion_content_comment('oboGo_HeterotypicCellCelladhesion',s("The","attachment","of","a","cell","to","a","cell","of","a","different","type","via","adhesion","molecules","."),4076690). assertion_content_comment('oboGo_HexokinaseDependentsignaling',s("A","series","of","molecular","signals","mediated","by","hexose","and","dependent","on","the","detection","of","hexokinase","."),4260359). assertion_content_comment('oboGo_HexokinaseIndependentsignaling',s("A","series","of","molecular","signals","mediated","by","hexose","and","independent","of","hexokinase","."),4260369). assertion_content_comment('oboGo_HexosePhosphate_Inorganicphosphateantiporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","hexose","phosphate","(","out",")","+","inorganic","phosphate","(","in",")","=","hexose","phosphate","(","in",")","+","inorganic","phosphate","(","out",")"),4292970). assertion_content_comment('oboGo_Hexulose_6_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-arabino-3-hexulose","6-phosphate","=","D-fructose","6-phosphate","."),4327433). assertion_content_comment('oboGo_Hexulose_6_PhosphateSynthaseActivity',s("Catalysis","of","the","reaction",":","D-ribulose","5-phosphate","+","formaldehyde","=","D-arabino-3-hexulose","6-phosphate","."),4327444). assertion_content_comment('oboGo_HighAffinitycopperiontransport',s("The","directed",",","high-affinity","movement","of","copper","(","Cu",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4289996). assertion_content_comment('oboGo_HighAffinityferricirontransport',s("The","directed",",","high-affinity","movement","of","ferric","(","Fe","(","III",")","or","Fe3","+",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4290030). assertion_content_comment('oboGo_HighAffinityglutamatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glutamate","(","out",")","+","H","+","(","out",")","=","glutamate","(","in",")","+","H","+","(","in",")"),4216041). assertion_content_comment('oboGo_HighAffinityhexosetransport',s("The","directed",",","high-affinity","movement","of","a","hexose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4253308). assertion_content_comment('oboGo_HighAffinityhydrogen_Glucosesymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glucose","+","H","+","=","glucose","+","H","+","This","activity","is","constitutive","and","therefore","always","present",",","regardless","of","demand",".","Symporter","activity","enables","the","active","transport","of","a","solute","across","a","membrane","by","a","mechanism","whereby","two","or","more","species","are","transported","together","in","the","same","direction","in","a","tightly","coupled","process","not","directly","linked","to","a","form","of","energy","other","than","chemiosmotic","energy",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4216452). assertion_content_comment('oboGo_HighAffinityironiontransport',s("The","directed",",","high-affinity","movement","of","iron","(","Fe",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4228931). assertion_content_comment('oboGo_HighAffinityLHistidinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-histidine","from","one","side","of","a","membrane","to","the","other",".","L-histidine","is","2-amino-3-","(","1H-imidazol-4-yl",")","propanoic","acid",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4215905). assertion_content_comment('oboGo_HighAffinitypotassiumionimport',s("The","directed",",","energized",",","high","affinity","movement","of","potassium","ions","into","a","cell","or","organelle",",","driven","by","cation","symport","with","hydrogen","or","sodium","ions","."),4334251). assertion_content_comment('oboGo_HighAffinitythiamine_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","thiamine","(","out",")","+","H","+","(","out",")","=","thiamine","(","in",")","+","H","+","(","in",")","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4359803). assertion_content_comment('oboGo_HighAffinitytryptophantransmembranetransporteractivity',s("Catalysis","of","the","high-affinity","transfer","of","L-tryptophan","from","one","side","of","a","membrane","to","the","other",".","Tryptophan","is","2-amino-3-","(","1H-indol-3-yl",")","propanoic","acid","."),4216883). assertion_content_comment('oboGo_HighAffinityzinciontransport',s("The","directed",",","high-affinity","movement","of","zinc","(","Zn",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","high","affinity","transport","the","transporter","is","able","to","bind","the","solute","even","if","it","is","only","present","at","very","low","concentrations","."),4228961). assertion_content_comment('oboGo_HighDensitylipoproteinparticleassembly',s("The","aggregation","and","arrangement","of","proteins","and","lipids","to","form","a","high-density","lipoprotein","particle","."),4125669). assertion_content_comment('oboGo_HighDensitylipoproteinparticlebinding',s("Interacting","selectively","and","non-covalently","with","high-density","lipoprotein","particle",",","a","lipoprotein","particle","with","a","high","density","(","typically","1.063-1.21","g/ml",")","and","a","diameter","of","5-10","nm","that","contains","APOAs","and","may","contain","APOCs","and","APOE","."),4174841). assertion_content_comment('oboGo_HighDensitylipoproteinparticleclearance',s("The","process","in","which","a","high-density","lipoprotein","particle","is","removed","from","the","blood","via","receptor-mediated","endocytosis","and","its","constituent","parts","degraded","."),4035712). assertion_content_comment('oboGo_HighDensitylipoproteinparticlereceptoractivity',s("Combining","with","a","high-density","lipoprotein","particle","to","initiate","a","change","in","cell","activity","."),4174858). assertion_content_comment('oboGo_HighDensitylipoproteinparticlereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","high-density","lipoprotein","receptor","."),4177463). assertion_content_comment('oboGo_HighDensitylipoproteinparticleremodeling',s("The","acquisition",",","loss","or","modification","of","a","protein","or","lipid","within","a","high-density","lipoprotein","particle",",","including","the","hydrolysis","of","triglyceride","by","hepatic","lipase",",","with","the","subsequent","loss","of","free","fatty","acid",",","and","the","transfer","of","cholesterol","esters","from","LDL","to","a","triglyceride-rich","lipoprotein","particle","by","cholesteryl","ester","transfer","protein","(","CETP",")",",","with","the","simultaneous","transfer","of","triglyceride","to","LDL","."),4355595). assertion_content_comment('oboGo_HighDensitylipoproteinparticle',s("A","lipoprotein","particle","with","a","high","density","(","typically","1.063-1.21","g/ml",")","and","a","diameter","of","5-10","nm","that","contains","APOAs","and","may","contain","APOCs","and","APOE",";","found","in","blood","and","carries","lipids","from","body","tissues","to","the","liver","as","part","of","the","reverse","cholesterol","transport","process","."),4355754). assertion_content_comment('oboGo_HighDensitylipoprotein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4216136). assertion_content_comment('oboGo_High_Mannose_OligosaccharideBeta_14_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","transfer","of","an","N-acetyl-D-glucosamine","residue","from","UDP-N-acetyl-D-glucosamine","to","the","4-position","of","a","mannose","linked","alpha-1",",","6","to","the","core","mannose","of","high-mannose","oligosaccharides","produced","by","Dictyostelium","discoideum","."),4343200). assertion_content_comment('oboGo_HighMolecularWeightcytochromechexadecaheme',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259306). assertion_content_comment('oboGo_HighPotentialironSulfurcarrier',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4296707). assertion_content_comment('oboGo_HighVoltageGatedcalciumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","high","voltage-gated","channel",".","A","high","voltage-gated","channel","is","a","channel","whose","open","state","is","dependent","on","high","voltage","across","the","membrane","in","which","it","is","embedded","."),4255283). assertion_content_comment('oboGo_HindbrainSpinalcordboundaryformation',s("The","process","whose","specific","outcome","is","the","formation","of","the","hindbrain-spinal","cord","boundary","."),4048596). assertion_content_comment('oboGo_HisPurkinjesystemcelldevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","a","His-Purkinje","cell","over","time",",","from","its","formation","to","the","mature","state",".","These","cells","form","the","fibers","that","regulate","cardiac","muscle","contraction","in","the","ventricles","."),4114481). assertion_content_comment('oboGo_HisPurkinjesystemcelldifferentiation',s("The","process","in","which","a","relatively","unspecialized","cell","acquires","the","specialized","structural","and/or","functional","features","of","a","cell","of","the","His-Purkinje","system",".","These","cells","form","the","fibers","regulate","cardiac","muscle","contraction","in","the","ventricles","."),4003732). assertion_content_comment('oboGo_HisPurkinjesystemcellfatecommitment',s("The","commitment","of","cells","to","His-Purkinje","cell","fates","and","their","capacity","to","differentiate","into","His-Purkinje","cells",".","These","cells","form","the","fibers","that","regulate","cardiac","muscle","contraction","in","the","ventricles","."),4114471). assertion_content_comment('oboGo_HisPurkinjesystemdevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","His-Purkinje","system","over","time",",","from","its","formation","to","the","mature","structure",".","The","His-Purkinje","system","receives","signals","from","the","AV","node","and","is","composed","of","the","fibers","that","regulate","cardiac","muscle","contraction","in","the","ventricles","."),4003713). assertion_content_comment('oboGo_HistamineGatedchloridechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","chloride","ion","by","a","channel","that","opens","when","histamine","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4237864). assertion_content_comment('oboGo_HistamineGatedchloridechannelcomplex',s("A","protein","complex","that","forms","a","transmembrane","channel","through","which","chloride","ions","may","pass","in","response","to","histamine","binding","to","the","channel","complex","or","one","of","its","constituent","parts","."),4044980). assertion_content_comment('oboGo_HistamineInducedgastricacidsecretion',s("The","regulated","release","of","gastric","acid","induced","by","the","interaction","of","histamine","with","H2","type","receptor","receptors","with","subsequent","activation","of","adenylate","cyclase","and","elevation","of","intracellular","cyclic","AMP","."),4383805). assertion_content_comment('oboGo_HistamineNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","histamine","=","N","(","tau",")","-methylhistamine","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4358955). assertion_content_comment('oboGo_HistidineAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","L-histidine","=","urocanate","+","NH3","."),4208129). assertion_content_comment('oboGo_HistidineCatabolicProcessTo2Oxoglutarate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","histidine","into","other","compounds",",","including","2-oxoglutarate","."),4242922). assertion_content_comment('oboGo_HistidineCatabolicProcessToHydantoin_5_Propionate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","histidine","into","other","compounds",",","including","hydantoin-5-propionate","."),4242885). assertion_content_comment('oboGo_HistidineCatabolicProcessToImidazol_5_Yl_Lactate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","histidine","into","other","compounds",",","including","imidazol-5-yl-lactate","."),4242909). assertion_content_comment('oboGo_HistidineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-histidine","+","acetyl-CoA","=","N","(","alpha",")","-acetyl-L-histidine","+","CoA","+","H","(","+",")"),4378910). assertion_content_comment('oboGo_HistidineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-histidine","+","tRNA","(","His",")","=","AMP","+","diphosphate","+","L-histidyl-tRNA","(","His",")"),4199867). assertion_content_comment('oboGo_HistidinolPhosphataseactivity',s("Catalysis","of","the","reaction",":","L-histidinol","phosphate","+","H","(","2",")","O","=","L-histidinol","+","phosphate","."),4206433). assertion_content_comment('oboGo_HistidinolPhosphatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-histidinol-phosphate","+","2-oxoglutarate","=","3-","(","imidazol-4-yl",")","-2-oxopropyl","phosphate","+","L-glutamate","."),4206386). assertion_content_comment('oboGo_HistidylTrnaaminoacylation',s("The","process","of","coupling","histidine","to","histidyl-tRNA",",","catalyzed","by","histidyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179679). assertion_content_comment('oboGo_HistoneAcetylLysinebinding',s("Interacting","selectively","and","non-covalently","with","an","acetylated","lysine","residue","within","a","histone","."),4175139). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH2AK5specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H2A","L-lysine","(","position","5",")","=","CoA","+","histone","H2A","N6-acetyl-L-lysine","(","position","5",")"),4328428). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH2AK9specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H2A","L-lysine","(","position","9",")","=","CoA","+","histone","H2A","N6-acetyl-L-lysine","(","position","9",")"),4289112). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH2BK12specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H2B","L-lysine","(","position","12",")","=","CoA","+","histone","H2B","N6-acetyl-L-lysine","(","position","12",")"),4289173). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH2BK5specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H2B","L-lysine","(","position","5",")","=","CoA","+","histone","H2B","N6-acetyl-L-lysine","(","position","5",")"),4289163). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K18specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","18",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","18",")"),4328535). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K23specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","23",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","23",")"),4328525). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K27specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","27",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","27",")"),4289153). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K36specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","36",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","36",")"),4288971). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K4specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","4",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","4",")"),4289143). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K56specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","56",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","56",")"),4336972). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K72specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","72",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","72",")"),4288981). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH3K9specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H3","L-lysine","(","position","9",")","=","CoA","+","histone","H3","N6-acetyl-L-lysine","(","position","9",")"),4328545). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH4K12specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H4","L-lysine","(","position","12",")","=","CoA","+","histone","H4","N6-acetyl-L-lysine","(","position","12",")"),4328418). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH4K16specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H4","L-lysine","(","position","16",")","=","CoA","+","histone","H4","N6-acetyl-L-lysine","(","position","16",")","This","reaction","represents","the","addition","of","an","acetyl","group","to","the","lysine","at","position","16","of","histone","H4","."),4361855). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH4K5specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H4","L-lysine","(","position","5",")","=","CoA","+","histone","H4","N6-acetyl-L-lysine","(","position","5",")"),4328515). assertion_content_comment('oboGo_HistoneAcetyltransferaseActivityH4K8specific',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","histone","H4","L-lysine","(","position","8",")","=","CoA","+","histone","H4","N6-acetyl-L-lysine","(","position","8",")"),4328408). assertion_content_comment('oboGo_HistoneArgininenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","histone",")","-arginine","=","S-adenosyl-L-homocysteine","+","(","histone",")","-N-methyl-arginine","."),4177096). assertion_content_comment('oboGo_HistoneDeacetylaseActivityH3K14specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-acetyl-L-lysine","(","position","14",")","+","H2O","=","histone","H3","L-lysine","(","position","14",")","+","acetate",".","This","reaction","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","14","of","the","histone","H3","protein","."),4319281). assertion_content_comment('oboGo_HistoneDeacetylaseActivityH3K16specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-acetyl-L-lysine","(","position","16",")","+","H2O","=","histone","H3","L-lysine","(","position","16",")","+","acetate",".","This","reaction","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","16","of","the","histone","H3","protein","."),4349380). assertion_content_comment('oboGo_HistoneDeacetylaseActivityH3K9specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-acetyl-L-lysine","(","position","9",")","+","H2O","=","histone","H3","L-lysine","(","position","9",")","+","acetate",".","This","reaction","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","9","of","the","histone","H3","protein","."),4329271). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3DimethylK4specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","dimethylated","lysine","at","position","4","of","the","histone","H3","protein","."),4353887). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3K27specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","lysine","at","position","27","of","the","histone","H3","protein","."),4171541). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3K36specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-methyl-L-lysine","(","position","36",")","+","alpha-ketoglutarate","+","O2","=","succinate","+","CO2","+","formaldehyde","+","lysine",".","This","reaction","is","the","removal","of","a","methyl","group","from","lysine","at","position","36","of","the","histone","H3","protein","."),4282104). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3K4specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","lysine","at","position","4","of","the","histone","H3","protein","."),4334747). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3K9specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-methyl-L-lysine","(","position","9",")","+","alpha-ketoglutarate","+","O2","=","succinate","+","CO2","+","formaldehyde","+","lysine",".","This","reaction","is","the","removal","of","a","methyl","group","from","lysine","at","position","9","of","the","histone","H3","protein","."),4334756). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3MonomethylK4specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-methyl-L-lysine","(","position","4",")","+","O2","+","FAD","+","H2O","=","histone","H3","L-lysine","(","position","4",")","+","H2O2","+","formaldehyde","+","FADH2",".","This","reaction","is","the","removal","of","a","methyl","group","from","monomethylated","lysine","at","position","4","of","the","histone","H3","protein","."),4353877). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3R2specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","arginine","at","position","2","of","the","histone","H3","protein","."),4342723). assertion_content_comment('oboGo_HistoneDemethylaseActivityH3TrimethylK4specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","trimethylated","lysine","at","position","4","of","the","histone","H3","protein","."),4353867). assertion_content_comment('oboGo_HistoneDemethylaseActivityH4K20specific',s("Catalysis","of","the","reaction",":","histone","H4","N6-methyl-L-lysine","(","position","20",")","+","2-oxoglutarate","+","O2","=","histone","H4","L-lysine","(","position","20",")","+","succinate","+","formaldehyde","+","CO2",".","This","reaction","is","the","removal","of","a","methyl","group","from","lysine","at","position","20","of","the","histone","H4","protein","."),4378335). assertion_content_comment('oboGo_HistoneDemethylaseActivityH4R3specific',s("Catalysis","of","the","removal","of","a","methyl","group","from","arginine","at","position","3","of","the","histone","H4","protein","."),4342792). assertion_content_comment('oboGo_HistoneH2AK5acetylation',s("The","modification","of","histone","H2A","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","5","of","the","histone","."),4328284). assertion_content_comment('oboGo_HistoneH2AK63Linkeddeubiquitination',s("A","protein","deubiquitination","process","in","which","a","K63-linked","ubiquitin","chain",",","i.e",".","a","polymer","of","ubiquitin","formed","by","linkages","between","lysine","residues","at","position","63","of","the","ubiquitin","monomers",",","is","removed","from","a","lysine","residue","in","histone","H2A","or","the","variant","H2AX","."),4174530). assertion_content_comment('oboGo_HistoneH2AK63Linkedubiquitination',s("A","histone","ubiquitination","process","in","which","a","polymer","of","ubiquitin",",","formed","by","linkages","between","lysine","residues","at","position","63","of","the","ubiquitin","monomers",",","is","added","to","a","lysine","residue","in","histone","H2A","or","the","variant","H2AX","."),4174440). assertion_content_comment('oboGo_HistoneH2AK9acetylation',s("The","modification","of","histone","H2A","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","9","of","the","histone","."),4328222). assertion_content_comment('oboGo_HistoneH2AS121phosphorylation',s("The","modification","of","histone","H2A","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","121","of","the","histone","."),4159144). assertion_content_comment('oboGo_HistoneH2AS1phosphorylation',s("The","modification","of","histone","H2A","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","1","of","the","histone","."),4328504). assertion_content_comment('oboGo_HistoneH2BConservedCTerminallysinedeubiquitination',s("A","histone","deubiquitination","process","in","which","a","ubiquitin","monomer","is","removed","from","a","conserved","lysine","residue","in","the","C-terminus","of","histone","H2B",".","The","conserved","lysine","residue","is","K119","in","fission","yeast",",","K123","in","budding","yeast",",","or","K120","in","mammals","."),4379576). assertion_content_comment('oboGo_HistoneH2BConservedCTerminallysineubiquitination',s("A","histone","ubiquitination","process","in","which","a","ubiquitin","monomer","is","added","to","a","conserved","lysine","residue","in","the","C-terminus","of","histone","H2B",".","The","conserved","lysine","residue","is","K119","in","fission","yeast",",","K123","in","budding","yeast",",","or","K120","in","mammals","."),4170668). assertion_content_comment('oboGo_HistoneH2BK12acetylation',s("The","modification","of","histone","H2B","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","12","of","the","histone","."),4328324). assertion_content_comment('oboGo_HistoneH2BK5acetylation',s("The","modification","of","histone","H2B","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","5","of","the","histone","."),4328241). assertion_content_comment('oboGo_HistoneH2BS14phosphorylation',s("The","modification","of","histone","H2B","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","14","of","the","histone","."),4328493). assertion_content_comment('oboGo_HistoneH3K14acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","14","of","the","histone","."),4128507). assertion_content_comment('oboGo_HistoneH3K18acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","18","of","the","histone","."),4328388). assertion_content_comment('oboGo_HistoneH3K23acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","23","of","the","histone","."),4328377). assertion_content_comment('oboGo_HistoneH3K27acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","27","of","the","histone","."),4328251). assertion_content_comment('oboGo_HistoneH3K27demethylation',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","lysine","at","position","27","of","the","histone","."),4171601). assertion_content_comment('oboGo_HistoneH3K27methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","lysine","at","position","27","of","the","histone","."),4135124). assertion_content_comment('oboGo_HistoneH3K36acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","36","of","the","histone","."),4328262). assertion_content_comment('oboGo_HistoneH3K36demethylation',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","lysine","at","position","36","of","the","histone","."),4174548). assertion_content_comment('oboGo_HistoneH3K36methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","lysine","at","position","36","of","the","histone","."),3975563). assertion_content_comment('oboGo_HistoneH3K4acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","4","of","the","histone","."),4328366). assertion_content_comment('oboGo_HistoneH3K4demethylation',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","lysine","at","position","4","of","the","histone","."),4349209). assertion_content_comment('oboGo_HistoneH3K4demethylationtrimethylH3K4Specific',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","a","trimetylated","lysine","at","position","4","of","the","histone","."),4349212). assertion_content_comment('oboGo_HistoneH3K4methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","lysine","at","position","4","of","the","histone","."),4121344). assertion_content_comment('oboGo_HistoneH3K56acetylationinresponsetodnadamage',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","56","of","the","histone","as","a","result","of","the","detection","of","DNA","damage","within","a","cell","."),4074338). assertion_content_comment('oboGo_HistoneH3K56acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","56","of","the","histone","."),4074336). assertion_content_comment('oboGo_HistoneH3K56deacetylation',s("The","modification","of","histone","H3","by","the","removal","of","an","acetyl","group","from","lysine","at","position","56","of","the","histone","."),4171172). assertion_content_comment('oboGo_HistoneH3K79acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","79","of","the","histone","."),4328273). assertion_content_comment('oboGo_HistoneH3K79methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","lysine","at","position","79","of","the","histone","."),4349243). assertion_content_comment('oboGo_HistoneH3K9acetylation',s("The","modification","of","histone","H3","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","9","of","the","histone","."),4143581). assertion_content_comment('oboGo_HistoneH3K9demethylation',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","lysine","at","position","9","of","the","histone","."),4347823). assertion_content_comment('oboGo_HistoneH3K9methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","lysine","at","position","9","of","the","histone","."),4121382). assertion_content_comment('oboGo_HistoneH3R17methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","arginine","at","position","17","of","the","histone","."),4348592). assertion_content_comment('oboGo_HistoneH3R26methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","arginine","at","position","26","of","the","histone","."),4348604). assertion_content_comment('oboGo_HistoneH3R2demethylation',s("The","modification","of","histone","H3","by","the","removal","of","a","methyl","group","from","arginine","at","position","2","of","the","histone","."),4180174). assertion_content_comment('oboGo_HistoneH3R2methylation',s("The","modification","of","histone","H3","by","addition","of","a","methyl","group","to","arginine","at","position","2","of","the","histone","."),4348580). assertion_content_comment('oboGo_HistoneH3S10phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","10","of","the","histone","."),4328439). assertion_content_comment('oboGo_HistoneH3S28phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","28","of","the","histone","."),4328450). assertion_content_comment('oboGo_HistoneH3T11phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","an","phosphate","group","to","a","threonine","residue","at","position","11","of","the","histone","."),4376566). assertion_content_comment('oboGo_HistoneH3T3phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","an","phosphate","group","to","a","threonine","residue","at","position","3","of","the","histone","."),4140129). assertion_content_comment('oboGo_HistoneH3T6phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","an","phosphate","group","to","a","threonine","residue","at","position","6","of","the","histone","."),4376557). assertion_content_comment('oboGo_HistoneH3Y41phosphorylation',s("The","modification","of","histone","H3","by","the","addition","of","a","phosphate","group","to","a","tyrosine","residue","at","position","41","of","the","histone","."),4376620). assertion_content_comment('oboGo_HistoneH4K12acetylation',s("The","modification","of","histone","H4","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","12","of","the","histone","."),4328314). assertion_content_comment('oboGo_HistoneH4K16acetylation',s("The","modification","of","histone","H4","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","16","of","the","histone","."),4143527). assertion_content_comment('oboGo_HistoneH4K20demethylation',s("The","modification","of","histone","H4","by","the","removal","of","a","methyl","group","from","lysine","at","position","20","of","the","histone","."),4378344). assertion_content_comment('oboGo_HistoneH4K20dimethylation',s("The","modification","of","histone","H4","by","addition","of","two","methyl","groups","to","lysine","at","position","20","of","the","histone","."),4349357). assertion_content_comment('oboGo_HistoneH4K20methylation',s("The","modification","of","histone","H4","by","addition","of","one","or","more","methyl","groups","to","lysine","at","position","20","of","the","histone","."),4131284). assertion_content_comment('oboGo_HistoneH4K20monomethylation',s("The","modification","of","histone","H4","by","addition","of","one","methyl","group","to","lysine","at","position","20","of","the","histone","."),4349345). assertion_content_comment('oboGo_HistoneH4K20trimethylation',s("The","modification","of","histone","H4","by","addition","of","three","methyl","groups","to","lysine","at","position","20","of","the","histone","."),4349369). assertion_content_comment('oboGo_HistoneH4K5acetylation',s("The","modification","of","histone","H4","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","5","of","the","histone","."),4328304). assertion_content_comment('oboGo_HistoneH4K8acetylation',s("The","modification","of","histone","H4","by","the","addition","of","an","acetyl","group","to","a","lysine","residue","at","position","8","of","the","histone","."),4328294). assertion_content_comment('oboGo_HistoneH4R3demethylation',s("The","modification","of","histone","H4","by","the","removal","of","a","methyl","group","from","arginine","at","position","3","of","the","histone","."),4180183). assertion_content_comment('oboGo_HistoneH4R3methylation',s("The","modification","of","histone","H4","by","addition","of","a","methyl","group","to","arginine","at","position","3","of","the","histone","."),4328470). assertion_content_comment('oboGo_HistoneH4S1phosphorylation',s("The","modification","of","histone","H4","by","the","addition","of","an","phosphate","group","to","a","serine","residue","at","position","1","of","the","histone","."),4328482). assertion_content_comment('oboGo_HistoneKinaseActivityH2AS121specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-121","residue","of","the","N-terminal","tail","of","histone","H2A","."),4159166). assertion_content_comment('oboGo_HistoneKinaseActivityH2AS1specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-1","residue","of","the","N-terminal","tail","of","histone","H2A","."),4288940). assertion_content_comment('oboGo_HistoneKinaseActivityH2BS14specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-14","residue","of","the","N-terminal","tail","of","histone","H2B","."),4288908). assertion_content_comment('oboGo_HistoneKinaseActivityH3S10specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-10","residue","of","the","N-terminal","tail","of","histone","H3","."),4382051). assertion_content_comment('oboGo_HistoneKinaseActivityH3S28specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-28","residue","of","the","N-terminal","tail","of","histone","H3","."),4288929). assertion_content_comment('oboGo_HistoneKinaseActivityH3T11specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","threonine-11","residue","of","the","N-terminal","tail","of","histone","H3","."),4376128). assertion_content_comment('oboGo_HistoneKinaseActivityH3T3specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","threonine-3","residue","of","the","N-terminal","tail","of","histone","H3","."),4159083). assertion_content_comment('oboGo_HistoneKinaseActivityH3T6specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","threonine-6","residue","of","the","N-terminal","tail","of","histone","H3","."),4376159). assertion_content_comment('oboGo_HistoneKinaseActivityH3Y41specific',s("The","modification","of","histone","H3","by","the","addition","of","a","phosphate","group","to","a","tyrosine","residue","at","position","41","of","the","histone","."),4376104). assertion_content_comment('oboGo_HistoneKinaseActivityH4S1specific',s("Catalysis","of","the","transfer","of","a","phosphate","group","to","the","serine-1","residue","of","the","N-terminal","tail","of","histone","H4","."),4288951). assertion_content_comment('oboGo_HistoneLysineNMethyltransferaseactivityh3K24specific',s("OBSOLETE",".","Catalysis","of","the","addition","of","a","methyl","group","onto","lysine","at","position","24","of","the","histone","H3","protein","."),4361846). assertion_content_comment('oboGo_HistoneLysinenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","L-lysine","=","S-adenosyl-L-homocysteine","+","histone","N6-methyl-L-lysine",".","The","methylation","of","peptidyl-lysine","in","histones","forms","N6-methyl-L-lysine",",","N6",",","N6-dimethyl-L-lysine","and","N6",",","N6",",","N6-trimethyl-L-lysine","derivatives","."),4283072). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH2AR3specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","histone","H2A",")","-arginine","(","position","3",")","=","S-adenosyl-L-homocysteine","+","(","histone","H2A",")","-N-methyl-arginine","(","position","3",")","This","reaction","is","the","addition","of","a","methyl","group","to","arginine","at","position","3","of","histone","H2A","."),4177106). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3K27specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H3","L-lysine","(","position","27",")","=","S-adenosyl-L-homocysteine","+","histone","H3","N6-methyl-L-lysine","(","position","27",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","27","of","the","histone","H3","protein","."),4361811). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3K36specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H3","L-lysine","(","position","36",")","=","S-adenosyl-L-homocysteine","+","histone","H3","N6-methyl-L-lysine","(","position","36",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","36","of","the","histone","H3","protein","."),4361822). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3K4specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H3","L-lysine","(","position","4",")","=","S-adenosyl-L-homocysteine","+","histone","H3","N6-methyl-L-lysine","(","position","4",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","4","of","the","histone","H3","protein","."),4314778). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3K79specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H3","L-lysine","(","position","79",")","=","S-adenosyl-L-homocysteine","+","histone","H3","N6-methyl-L-lysine","(","position","79",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","79","of","the","histone","H3","protein","."),4318910). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3K9specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H3","L-lysine","(","position","9",")","=","S-adenosyl-L-homocysteine","+","histone","H3","N6-methyl-L-lysine","(","position","9",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","9","of","the","histone","H3","protein","."),4361833). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3R17specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","histone","H3",")","-arginine","(","position","17",")","=","S-adenosyl-L-homocysteine","+","(","histone","H3",")","-N-methyl-arginine","(","position","17",")","This","reaction","is","the","addition","of","a","methyl","group","to","arginine","at","position","17","of","histone","H3","."),4380016). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH3R2specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","histone","H3",")","-arginine","(","position","2",")","=","S-adenosyl-L-homocysteine","+","(","histone","H3",")","-N-methyl-arginine","(","position","2",")","This","reaction","is","the","addition","of","a","methyl","group","to","arginine","at","position","2","of","histone","H3","."),4177117). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH4K20specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","histone","H4","L-lysine","(","position","20",")","=","S-adenosyl-L-homocysteine","+","histone","H4","N6-methyl-L-lysine","(","position","20",")","This","reaction","is","the","addition","of","a","methyl","group","onto","lysine","at","position","20","of","the","histone","H4","protein","."),4315595). assertion_content_comment('oboGo_HistoneMethyltransferaseActivityH4R3specific',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","histone","H4",")","-arginine","(","position","3",")","=","S-adenosyl-L-homocysteine","+","(","histone","H4",")","-N-methyl-arginine","(","position","3",")","This","reaction","is","the","addition","of","a","methyl","group","to","arginine","at","position","3","of","histone","H4","."),4288888). assertion_content_comment('oboGo_HistoneMRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","a","histone","mRNA","molecule","."),4224168). assertion_content_comment('oboGo_HistonePeptidylProlylisomerization',s("The","modification","of","a","histone","by","cis-trans","isomerization","of","a","proline","residue","."),4362790). assertion_content_comment('oboGo_HistonePreMrna3endprocessingcomplex',s("A","ribonucleoprotein","that","binds","to","specific","sites","in",",","and","is","required","for","cleavage","of",",","the","3","'","-end","of","histone","pre-mRNAs",".","The","complex","contains","the","U7","snRNP","and","additional","proteins",",","including","the","stem-loop","binding","protein","(","SLBP",")","and","the","exonuclease","3","'","hExo/Eri-1","."),4165382). assertion_content_comment('oboGo_HistonePreMrnadcpbinding',s("Interacting","selectively","and","non-covalently","with","the","downstream","cleavage","product","(","DCP",")","generated","by","histone","pre-mRNA","3","'","-end","processing","."),4165424). assertion_content_comment('oboGo_HistonePreMrnastemLoopbinding',s("Interacting","selectively","and","non-covalently","with","a","conserved","stem-loop","structure","found","in","histone","pre-mRNAs","."),4165415). assertion_content_comment('oboGo_HistoneSerinephosphorylation',s("The","modification","of","histones","by","addition","of","a","phosphate","group","to","a","serine","residue","."),4159141). assertion_content_comment('oboGo_HistoneSpecificchaperoneactivity',s("OBSOLETE",".","Assists","in","chromatin","assembly","by","chaperoning","histones","on","to","replicating","DNA",",","but","is","not","a","component","of","the","assembled","nucleosome","when","performing","its","normal","biological","function","."),4192329). assertion_content_comment('oboGo_HistoneThreoninephosphorylation',s("The","modification","of","histones","by","addition","of","a","phosphate","group","to","a","threonine","residue","."),4140126). assertion_content_comment('oboGo_HistoneTyrosinephosphorylation',s("The","modification","of","histones","by","addition","of","a","phosphate","group","to","a","tyrosine","residue","."),4376576). assertion_content_comment('oboGo_HLAAspecificactivatingmhcclassireceptoractivity',s("Combining","with","a","MHC","class","I","molecule","of","the","HLA-A","subclass","to","mediate","signaling","that","activates","a","lymphocyte","."),4310996). assertion_content_comment('oboGo_HLAAspecificinhibitorymhcclassireceptoractivity',s("Combining","with","a","MHC","class","I","molecule","of","the","HLA-A","subclass","to","mediate","signaling","that","inhibits","activation","of","a","lymphocyte","."),4310978). assertion_content_comment('oboGo_HLABspecificinhibitorymhcclassireceptoractivity',s("Combining","with","a","MHC","class","I","molecule","of","the","HLA-B","subclass","to","mediate","signaling","that","inhibits","activation","of","a","lymphocyte","."),4311005). assertion_content_comment('oboGo_HLACspecificinhibitorymhcclassireceptoractivity',s("Combining","with","a","MHC","class","I","molecule","of","the","HLA-C","subclass","to","mediate","signaling","that","inhibits","activation","of","a","lymphocyte","."),4310933). assertion_content_comment('oboGo_HNK_1SulfotransferaseActivity',s("Catalysis","of","the","synthesis","of","the","HKK-1","carbohydrate","epitope",";","adds","a","sulfate","group","to","a","precursor",",","GlcA-beta-","(","1",",","3",")","-Gal-beta-","(","1",",","4",")","-GlcNAc-beta-","(","1-","&","gt",";","R",")",",","forming","sulfo-3GlcA-beta-","(","1",",","3",")","-Gal-beta-","(","1",",","4",")","-GlcNAc-beta-","(","1-","&","gt",";","R",")"),4303811). assertion_content_comment('oboGo_Holin_2',s("OBSOLETE",".","Primary","function","of","holins","appears","to","be","transport","of","murein","hydrolases","across","the","cytoplasmic","membrane","to","the","cell","wall","of","bacteria",",","where","these","enzymes","hydrolyze","the","cell","wall","polymer","as","a","prelude","to","cell","lysis",".","When","chromosomally","encoded",",","these","enzymes","are","therefore","autolysins",".","Holins","may","also","facilitate","leakage","of","electrolytes","and","nutrients","from","the","cell","cytoplasm",",","thereby","promoting","cell","death",".","Some","catalyze","export","of","nucleases","."),4297431). assertion_content_comment('oboGo_HoloAcylCarrierProteinbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","holo-","[","acyl-carrier","protein","]"),4318721). assertion_content_comment('oboGo_HoloAcylCarrierProteinsynthaseactivity',s("Catalysis","of","the","reaction",":","CoA","+","substrate-serine","=","adenosine","3","'",",","5","'","-bisphosphate","+","substrate-serine-4","'","-phosphopantetheine",".","The","transfer","of","the","4","'","-phosphopantetheine","(","Ppant",")","co-factor","from","coenzyme","A","to","the","hydroxyl","side","chain","of","the","serine","residue","of","acyl-","or","peptidyl-carrier","protein","(","ACP","or","PCP",")","to","convert","them","from","the","apo","to","the","holo","form","."),4249436). assertion_content_comment('oboGo_HoloAcylCarrierproteinsynthasecomplex',s("OBSOLETE",".","An","enzyme","complex","that","catalyzes","the","formation","of","holo-","[","acyl-carrier","protein","]","from","CoA","and","apo-","[","acyl-carrier","protein","]"),4259704). assertion_content_comment('oboGo_HoloCitratelyasesynthaseactivity',s("Catalysis","of","the","reaction",":","apo-citrate","lyase","+","2","'","-","(","5","'","'","-triphosphoribosyl",")","-3","'","-dephospho-CoA","=","diphosphate","+","holo-citrate","lyase","."),4269011). assertion_content_comment('oboGo_HolocytochromeCsynthaseactivity',s("Catalysis","of","the","reaction",":","holocytochrome","c","=","apocytochrome","c","+","heme","."),4206232). assertion_content_comment('oboGo_HomeostasisOfNumberOfCellsInAFreeLivingpopulation',s("The","biological","process","involved","in","maintaining","the","steady-state","number","of","cells","within","a","population","of","free-living","cells","such","as","the","bacteria","in","the","gut","."),4026583). assertion_content_comment('oboGo_HomocysteineSMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","L-homocysteine","=","S-adenosyl-L-homocysteine","+","L-methionine","."),4249470). assertion_content_comment('oboGo_Homogentisate12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","homogentisate","+","O","(","2",")","=","4-maleylacetoacetate","+","H","(","+",")"),4206352). assertion_content_comment('oboGo_HomoserineOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-homoserine","+","acetyl-CoA","=","O-acetyl-L-homoserine","+","CoA","."),4206302). assertion_content_comment('oboGo_HomoserineOSuccinyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-homoserine","+","succinyl-CoA","=","O-succinyl-L-homoserine","+","CoA","."),4249503). assertion_content_comment('oboGo_HomospermidineSynthaseSpermidineSpecificactivity',s("Catalysis","of","the","reaction",":","spermidine","+","putrescine","=","sym-homospermidine","+","propane-1",",","3-diamine","."),4269169). assertion_content_comment('oboGo_HomotypicCellCelladhesion',s("The","attachment","of","a","cell","to","a","second","cell","of","the","identical","type","via","adhesion","molecules","."),4076745). assertion_content_comment('oboGo_HormoneMediatedsignalingpathway',s("A","series","of","molecular","signals","mediated","by","the","detection","of","a","hormone","."),3992925). assertion_content_comment('oboGo_HormoneSensitivelipaseactivity',s("Catalysis","of","the","reactions",":","diacylglycerol","+","H2O","=","monoacylglycerol","+","a","carboxylate",";","triacylglycerol","+","H2O","=","diacylglycerol","+","a","carboxylate",";","and","monoacylglycerol","+","H2O","=","glycerol","+","a","carboxylate","."),4343519). assertion_content_comment('oboGo_HorsetailAstralmicrotubulearray',s("An","array","of","astral","microtubules","that","emanates","from","the","spindle","pole","body","during","meiosis","and","facilitates","horsetail","nuclear","movement","."),4329193). assertion_content_comment('oboGo_HorsetailAstralmicrotubuleorganization',s("A","process","that","is","carried","out","at","the","cellular","level","which","results","in","the","assembly",",","arrangement","of","constituent","parts",",","or","disassembly","of","the","horsetail-astral","array",",","a","structure","of","astral","microtubules","that","emanates","from","the","spindle","pole","body","during","meiosis","."),4329216). assertion_content_comment('oboGo_HostBacteroidContainingsymbiosome',s("A","symbiosome","containing","any","of","various","structurally","modified","bacteria",",","such","as","those","occurring","on","the","root","nodules","of","leguminous","plants",",","of","a","host","cell","."),4095096). assertion_content_comment('oboGo_HostCellEndoplasmicReticulumGolgiintermediatecompartmentmembrane',s("The","lipid","bilayer","surrounding","any","of","the","compartments","of","the","host","cell","ER-Golgi","intermediate","compartment","system","."),4097202). assertion_content_comment('oboGo_HostCellEndoplasmicReticulumGolgiintermediatecompartment',s("A","complex","system","of","membrane-bounded","compartments","located","between","host","cell","endoplasmic","reticulum","(","ER",")","and","the","host","Golgi","complex",",","with","a","distinctive","membrane","protein","composition",";","involved","in","ER-to-Golgi","transport","."),4097189). assertion_content_comment('oboGo_HostIntracellularMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","as","found","in","host","cells",",","bounded","by","a","single","or","double","lipid","bilayer","membrane","and","occurring","within","the","cell",".","Includes","the","nucleus",",","mitochondria",",","plastids",",","vacuoles",",","and","vesicles",".","Excludes","the","plasma","membrane",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4095090). assertion_content_comment('oboGo_HostPathogeninteraction',s("OBSOLETE",".","Any","interaction","between","a","pathogen","and","its","host","organism","."),4309417). assertion_content_comment('oboGo_HostSeekingbehavior',s("The","specific","actions","or","reactions","of","an","organism","that","are","associated","with","finding","a","host","organism",";","may","include","behavioral","responses","to","light",",","temperature",",","or","chemical","emanations","from","the","prospective","host","."),4067292). assertion_content_comment('oboGo_Hrd1pUbiquitinLigaseERADLcomplex',s("A","multiprotein","complex","that","recognizes","and","ubiquitinates","proteins","with","misfolded","luminal","domains","during","ER-associated","protein","degradation","(","ERAD",")","In","S",".","cerevisiae",",","this","complex","contains","the","ubiquitin","ligase","Hrd1p","."),4363457). assertion_content_comment('oboGo_Hrd1pUbiquitinLigaseERADMcomplex',s("A","multiprotein","complex","that","recognizes","and","ubiquitinates","proteins","with","misfolded","membrane","domains","during","ER-associated","protein","degradation","(","ERAD",")","In","S",".","cerevisiae",",","this","complex","contains","the","ubiquitin","ligase","Hrd1p","."),4363466). assertion_content_comment('oboGo_HydrogenExportingatpaseactivityphosphorylativemechanism',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","=","ADP","+","phosphate","+","H","+","(","out",")",";","by","a","phosphorylative","mechanism","."),4252899). assertion_content_comment('oboGo_HydrogenobyrinicAcidACDiamidesynthaseglutamineHydrolysingactivity',s("Catalysis","of","the","reaction",":","2","L-glutamine","+","2","ATP","+","2","H","(","2",")","O","+","hydrogenobyrinate","=","2","L-glutamate","+","2","ADP","+","4","H","(","+",")","+","hydrogenobyrinate","a",",","c-diamide","+","2","phosphate","."),4327410). assertion_content_comment('oboGo_HydrogenPeroxideMediatedprogrammedcelldeath',s("Programmed","cell","death","induced","by","hydrogen","peroxide",".","Programmed","cell","death","is","the","cell","death","resulting","from","activation","of","endogenous","cellular","processes","."),4333499). assertion_content_comment('oboGo_Hydrogen_PotassiumExchangingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","+","K","+","(","out",")","=","ADP","+","phosphate","+","H","+","(","out",")","+","K","+","(","in",")"),4248373). assertion_content_comment('oboGo_Hydrogen_PotassiumExchangingatpasecomplex',s("A","protein","complex","that","possesses","hydrogen",":","potassium-exchanging","ATPase","activity",";","characterized","in","animal","cells",",","where","it","maintains","ionic","gradients","of","Na","+","and","K","+","at","the","expense","of","ATP","hydrolysis",";","The","complex","contains","two","obligatory","subunits",",","the","catalytic","alpha","subunit","and","a","glycosylated","beta","subunit",";","two","additional","subunits",",","gamma","and","channel-inducing","factor","(","CHIF",")",",","may","also","be","present","."),4008291). assertion_content_comment('oboGo_HydrogenSodiumTranslocatingatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","(","Na","+","or","H","+",")","(","in",")","=","ADP","+","phosphate","+","(","Na","+","or","H","+",")","(","out",")"),4292016). assertion_content_comment('oboGo_HydrogenSulfidesAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","S","(","2-",")","=","CoA","+","thioacetate","."),4378844). assertion_content_comment('oboGo_HydrogenTranslocatingaTypeatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","=","ADP","+","phosphate","+","H","+","(","out",")","Found","in","archae","."),4304874). assertion_content_comment('oboGo_HydrogenTranslocatingfTypeatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","=","ADP","+","phosphate","+","H","+","(","out",")","Found","in","eukaryotic","mitochondria","and","chloroplasts","and","in","bacteria","."),4304860). assertion_content_comment('oboGo_HydrogenTranslocatingpyrophosphataseactivity',s("Catalysis","of","the","hydrolysis","of","pyrophosphate",",","which","generates","a","proton","motive","force","."),4260938). assertion_content_comment('oboGo_HydrogenTranslocatingvTypeatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","=","ADP","+","phosphate","+","H","+","(","out",")","Found","in","vacuoles","of","eukaryotes","and","in","bacteria","."),4346624). assertion_content_comment('oboGo_HydrogenTransportingatpsynthasecouplingfactorcf0',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4219877). assertion_content_comment('oboGo_HydrogenTransportingtwoSectoratpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","+","H","+","(","in",")","=","ADP","+","phosphate","+","H","+","(","out",")"),4185982). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidAnhydridesInPhosphorusContaininganhydrides',s("Catalysis","of","the","hydrolysis","of","any","acid","anhydride","which","contains","phosphorus","."),4159549). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidAnhydridesInSulfonylContaininganhydrides',s("Catalysis","of","the","hydrolysis","of","any","acid","anhydride","which","contains","a","sulfonyl","group",",","-SO2-","."),4263170). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidCarbonCarbonbondsinketonicsubstances',s("Catalysis","of","the","hydrolysis","of","any","acid","carbon-carbon","bond","in","a","ketonic","substance",",","a","substance","containing","a","keto","(","C","=","O",")","group","."),4208397). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidCarbonCarbonbonds',s("Catalysis","of","the","hydrolysis","of","any","acid","carbon-carbon","bond","."),4208395). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidCarbonPhosphorusbonds',s("Catalysis","of","the","hydrolysis","of","any","acid","carbon-phosphorus","bond","."),4262961). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidHalideBondsInCHalidecompounds',s("Catalysis","of","the","hydrolysis","of","any","acid","halide","bond","in","substances","containing","halogen","atoms","in","organic","linkage","."),4237254). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidPhosphorusNitrogenbonds',s("Catalysis","of","the","hydrolysis","of","any","acid","phosphorus-nitrogen","bond","."),4263123). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidSulfurNitrogenbonds',s("Catalysis","of","the","hydrolysis","of","any","acid","sulfur-nitrogen","bond","."),4274223). assertion_content_comment('oboGo_HydrolaseActivityActingOnAcidSulfurSulfurbonds',s("Catalysis","of","the","hydrolysis","of","any","acid","sulfur-sulfur","bond","."),4301654). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsincyclicamides',s("Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","a","cyclic","amide","."),4211312). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsincyclicamidines',s("Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","a","cyclic","amidine",",","a","compound","of","the","form","R-C","(","=","NH",")","-NH2","."),4185526). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsinlinearamides',s("Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","a","linear","amide","."),4170157). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsinlinearamidines',s("Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","a","linear","amidine",",","a","compound","of","the","form","R-C","(","=","NH",")","-NH2","."),4172127). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsinnitriles',s("Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","a","nitrile",",","a","compound","containing","the","cyano","radical",",","-CN","."),4182587). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebondsinothercompounds',s("OBSOLETE",".","Catalysis","of","the","hydrolysis","of","any","non-peptide","carbon-nitrogen","bond","in","substances","other","than","amides",",","amidines","and","nitriles","."),4301677). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonNitrogenbutnotpeptidebonds',s("Catalysis","of","the","hydrolysis","of","any","carbon-nitrogen","bond",",","C-N",",","with","the","exception","of","peptide","bonds","."),4170154). assertion_content_comment('oboGo_HydrolaseActivityActingOnCarbonSulfurbonds',s("Catalysis","of","the","hydrolysis","of","any","carbon-sulfur","bond",",","C-S","."),4274915). assertion_content_comment('oboGo_HydrolaseActivityHydrolyzingNGlycosylcompounds',s("Catalysis","of","the","hydrolysis","of","any","N-glycosyl","bond","."),4157590). assertion_content_comment('oboGo_HydrolaseActivityHydrolyzingOGlycosylcompounds',s("Catalysis","of","the","hydrolysis","of","any","O-glycosyl","bond","."),4172798). assertion_content_comment('oboGo_HydroLyaseactivity',s("Catalysis","of","the","cleavage","of","a","carbon-oxygen","bond","by","elimination","of","water","."),4181439). assertion_content_comment('oboGo_Hydroquinone12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","hydroquinone","+","O2","=","cis",",","trans-4-hydroxymuconic","semialdehyde","."),4278773). assertion_content_comment('oboGo_HydroxyacidOxoacidtranshydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-hydroxybutanoate","+","2-oxoglutarate","=","acetoacetate","+","(","R",")","-2-hydroxyglutarate","."),4378872). assertion_content_comment('oboGo_HydroxybutyrateDimerhydrolaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-3-","[","(","R",")","-3-hydroxybutanoyloxy","]","butanoate","+","H","(","2",")","O","=","2","(","R",")","-3-hydroxybutanoate","+","H","(","+",")"),4378945). assertion_content_comment('oboGo_Hydroxycinnamate4BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","4-coumarate","+","UDP-D-glucose","=","4-O-beta-D-glucosyl-4-hydroxycinnamate","+","UDP","."),4366684). assertion_content_comment('oboGo_HydroxyectoineTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","hydroxyectoine","(","out/in",")","=","ADP","+","phosphate","+","hydroxyectoine","(","in/out",")"),4337838). assertion_content_comment('oboGo_HydroxymethylFormylAndrelatedtransferaseactivity',s("Catalysis","of","the","transfer","of","a","hydroxymethyl-","or","formyl","group","from","one","compound","(","donor",")","to","another","(","acceptor",")"),4189229). assertion_content_comment('oboGo_HydroxymethylglutarylCoahydrolaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","+","H","(","2",")","O","=","3-hydroxy-3-methylglutarate","+","CoA","+","H","(","+",")"),4379078). assertion_content_comment('oboGo_HydroxymethylglutarylCoalyaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","=","acetoacetate","+","acetyl-CoA","."),4206654). assertion_content_comment('oboGo_HydroxymethylglutarylCoareductaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-mevalonate","+","CoA","+","2","NAD","(","+",")","=","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","+","2","H","(","+",")","+","2","NADH","."),4314177). assertion_content_comment('oboGo_HydroxymethylglutarylCoareductasenadphactivity',s("Catalysis","of","the","reaction",":","(","R",")","-mevalonate","+","CoA","+","2","NADP","(","+",")","=","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","+","2","H","(","+",")","+","2","NADPH","."),4206695). assertion_content_comment('oboGo_HydroxymethylglutarylCoareductasenadphkinaseactivity',s("Catalysis","of","the","reaction",":","[","3-hydroxy-3-methylglutaryl-CoA","reductase","(","NADPH",")","]","+","ATP","=","[","3-hydroxy-3-methylglutaryl-CoA","reductase","(","NADPH",")","]","phosphate","+","ADP","."),4369012). assertion_content_comment('oboGo_HydroxymethylglutarylCoareductasenadphPhosphataseactivity',s("Catalysis","of","the","reaction",":","H2O","+","[","hydroxymethylglutaryl-CoA","reductase","(","NADPH",")","]","phosphate","=","phosphate","+","[","hydroxymethylglutaryl-CoA","reductase","(","NADPH",")","]"),4368646). assertion_content_comment('oboGo_HydroxymethylglutarylCoasynthaseactivity',s("Catalysis","of","the","reaction",":","acetoacetyl-CoA","+","acetyl-CoA","+","H","(","2",")","O","=","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","+","CoA","+","H","(","+",")"),4206708). assertion_content_comment('oboGo_HydroxyneurosporeneOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","demethylspheroidene","+","S-adenosyl-L-methionine","=","spheroidene","+","S-adenosyl-L-homocysteine","."),4327423). assertion_content_comment('oboGo_HydroxyNicotineoxidaseactivity',s("Catalysis","of","the","reaction",":","6-hydroxynicotine","+","H2O","+","O2","=","1-","(","6-hydroxypyrid-3-yl",")","-4-","(","methylamino",")","butan-1-one","+","hydrogen","peroxide","."),4237111). assertion_content_comment('oboGo_Hydroxyphenylacetonitrile2Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","4-hydroxyphenylacetonitrile","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","4-hydroxymandelonitrile","+","H","(","2",")","O","+","NADP","(","+",")"),4365006). assertion_content_comment('oboGo_Hydroxyquinol12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","benzene-1",",","2",",","4-triol","+","O2","=","3-hydroxy-cis",",","cis-muconate","."),4275391). assertion_content_comment('oboGo_HygromycinB7OPhosphotransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","hygromycin","B","=","7","'","'","-O-phosphohygromycin","B","+","ADP","+","2","H","(","+",")"),4248355). assertion_content_comment('oboGo_Hyoscyamine6SDioxygenaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-hyoscyamine","+","O","(","2",")","=","(","6S",")","-6-hydroxyhyoscyamine","+","CO","(","2",")","+","succinate","."),4379153). assertion_content_comment('oboGo_HypothalamicTangentialMigrationUsingCellAxoninteractions',s("The","movement","of","a","hypothalamic","neuronal","precursor","tangentially","through","the","forebrain","using","an","interaction","of","the","migrating","cells","with","axons","of","other","neurons","."),4050695). assertion_content_comment('oboGo_HypothalamusGonadotrophinReleasinghormoneneurondevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","a","hypothalamus","gonadotrophin-releasing","hormone","neuron","over","time",",","from","initial","commitment","of","its","fate",",","to","the","fully","functional","differentiated","cell","."),4047612). assertion_content_comment('oboGo_HypothalamusGonadotrophinReleasinghormoneneurondifferentiation',s("The","process","in","which","a","relatively","unspecialized","cell","acquires","specialized","features","of","a","neuron","located","in","the","hypothalamus",".","These","neurons","release","gonadotrophin-releasing","hormone","as","a","neural","transmitter","."),4047610). assertion_content_comment('oboGo_HypothalamusGonadotrophinReleasinghormoneneuronfatecommitment',s("The","process","in","which","the","developmental","fate","of","a","cell","becomes","restricted","such","that","it","will","develop","into","a","hypothalamus","neuron","that","releases","gonadotrophin-releasing","hormone","."),4047644). assertion_content_comment('oboGo_IAaacomplex',s("Protease","complex","of","the","mitochondrial","inner","membrane","whose","catalytic","residues","lie","on","the","intermembrane","space","side","of","the","inner","membrane",";","involved","in","mitochondrial","protein","turnover",".","Contains","a","subunit","belonging","to","the","AAA","family","of","ATP-dependent","metalloproteases","."),4057591). assertion_content_comment('oboGo_IAAAlaconjugatehydrolaseactivity',s("Catalysis","of","the","reaction",":","indole-3-acetyl-alanine","+","H2O","=","indole-3-acetate","+","L-alanine","."),4334170). assertion_content_comment('oboGo_IAAAminoacidconjugatehydrolaseactivity',s("Catalysis","of","the","cleavage","of","the","amide","bond","between","IAA","(","auxin",")","and","the","conjugated","amino","acid","."),4334161). assertion_content_comment('oboGo_IAALeuconjugatehydrolaseactivity',s("Catalysis","of","the","reaction",":","indole-3-acetyl-leucine","+","H2O","=","indole-3-acetate","+","L-leucine","."),4335709). assertion_content_comment('oboGo_IAAPheconjugatehydrolaseactivity',s("Catalysis","of","the","reaction",":","indole-3-acetyl-phenylalanine","+","H2O","=","indole-3-acetate","+","phenylalanine","."),4335727). assertion_content_comment('oboGo_ICAM_3ReceptorActivity',s("Combining","with","ICAM-3",",","intercellular","adhesion","molecule","3",",","to","initiate","a","change","in","cell","activity",".","ICAM-3",",","or","CD50",",","are","constitutively","expressed","on","monocytes",",","granulocytes","and","lymphocytes",";","on","physiological","stimulation",",","they","become","transiently","phosphorylated","on","serine","residues","."),4309703). assertion_content_comment('oboGo_IcosanoylCoasynthaseactivity',s("Catalysis","of","the","reaction",":","stearoyl-CoA","+","malonyl-CoA","+","2","NAD","(","P",")","H","+","2","H","+","=","icosanoyl-CoA","+","CO2","+","2","NAD","(","P",")","+"),4342850). assertion_content_comment('oboGo_Iduronate_2_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","2-sulfate","groups","of","the","L-iduronate","2-sulfate","units","of","dermatan","sulfate",",","heparan","sulfate","and","heparin","."),4206758). assertion_content_comment('oboGo_IgDImmunoglobulinComplexGPIAnchored',s("A","protein","complex","composed","of","two","identical","immunoglobulin","heavy","chains","of","the","IgD","isotype","and","two","identical","immunoglobulin","light","chains",",","held","together","by","disulfide","bonds",",","and","bound","via","a","GPI-anchor","to","the","plasma","membrane","of","B","cells","."),4169735). assertion_content_comment('oboGo_IgHeavyChainBoundendoplasmicreticulumchaperonecomplex',s("A","protein","complex","that","is","located","in","the","endoplasmic","reticulum","(","ER",")","and","is","formed","by","the","association","of","an","immunoglobulin","heavy","chain","with","the","proteins","of","the","ER","chaperone","complex",";","the","latter","include","BiP",",","GRP94",";","CaBP1",",","protein","disulfide","isomerase","(","PDI",")",",","ERdj3",",","cyclophilin","B",",","ERp72",",","GRP170",",","UDP-glucosyltransferase",",","and","SDF2-L1","."),4354464). assertion_content_comment('oboGo_IKappabkinasenfKappabcascade',s("A","series","of","reactions","initiated","by","the","activation","of","the","transcription","factor","NF-kappaB",".","NF-kappaB","is","sequestered","by","the","inhibitor","I-kappaB",",","and","is","released","when","I-kappaB","is","phosphorylated","by","activated","I-kappaB","kinase","."),4016202). assertion_content_comment('oboGo_IKappabnfKappabcomplex',s("A","protein","complex","containing","an","I-kappaB","protein","and","one","or","more","copies","of","an","NF-kappaB","protein",";","mediates","regulation","of","NF-kappaB","activity","by","I-kappaB","."),4337884). assertion_content_comment('oboGo_IKappabphosphorylation',s("The","process","of","introducing","a","phosphate","group","into","an","I-kappaB","protein","."),4016723). assertion_content_comment('oboGo_ImaginalDiscDerivedappendagedevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","an","appendage","over","time",",","from","its","formation","in","the","imaginal","disc","to","the","mature","structure",".","An","appendage","is","an","organ","or","part","that","is","attached","to","the","trunk","of","an","organism","."),3982441). assertion_content_comment('oboGo_ImaginalDiscDerivedappendagemorphogenesis',s("The","process","in","which","the","anatomical","structures","of","appendages","are","generated","and","organized",".","An","appendage","is","an","organ","or","part","that","is","attached","to","the","trunk","of","an","organism","."),3982443). assertion_content_comment('oboGo_ImaginalDiscDerivedfemalegenitaliadevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","female","genitalia","over","time",",","from","formation","as","part","of","the","genital","disc","to","the","mature","structure",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4105337). assertion_content_comment('oboGo_ImaginalDiscDerivedfemalegenitaliamorphogenesis',s("The","process","in","which","the","anatomical","structures","of","female","genitalia","are","generated","and","organized","from","the","genital","disc","."),4105349). assertion_content_comment('oboGo_ImaginalDiscDerivedgenitaliadevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","genitalia","over","time",",","from","formation","as","part","of","the","genital","disc","to","the","mature","structure",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4018074). assertion_content_comment('oboGo_ImaginalDiscDerivedgenitaliamorphogenesis',s("The","process","in","which","the","anatomical","structures","of","genitalia","are","generated","and","organized","from","the","genital","imaginal","disc","."),4105321). assertion_content_comment('oboGo_ImaginalDiscDerivedlegjointmorphogenesis',s("The","process","in","which","the","anatomical","structures","of","an","imaginal","disc-derived","leg","joint","are","generated","and","organized",".","The","leg","joint","is","a","flexible","region","that","separates","the","rigid","sections","of","a","leg","to","allow","movement","in","a","controlled","manner",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4034504). assertion_content_comment('oboGo_ImaginalDiscDerivedlegmorphogenesis',s("The","process","in","which","the","anatomical","structures","of","a","leg","derived","from","an","imaginal","disc","are","generated","and","organized",".","A","leg","is","a","limb","on","which","an","animal","walks","and","stands",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4018168). assertion_content_comment('oboGo_ImaginalDiscDerivedlimbmorphogenesis',s("The","process","in","which","the","anatomical","structures","of","limbs","that","are","derived","from","an","imaginal","disc","are","generated","and","organized",".","A","limb","is","an","appendage","of","an","animal","used","for","locomotion","or","grasping",".","An","example","of","this","process","is","found","in","Drosophila","melanogaster","."),4018144). assertion_content_comment('oboGo_ImaginalDiscDerivedmalegenitaliadevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","male","genitalia","over","time",",","from","formation","as","part","of","the","genital","disc","to","the","mature","structure",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4105291). assertion_content_comment('oboGo_ImaginalDiscDerivedmalegenitaliamorphogenesis',s("The","process","in","which","the","anatomical","structures","of","male","genitalia","are","generated","and","organized","from","the","genital","imaginal","disc","."),4105326). assertion_content_comment('oboGo_ImaginalDiscDerivedwingexpansion',s("The","process","of","expanding","or","inflating","the","folded","imaginal","disc-derived","pupal","wing",",","and","the","adhering","of","the","dorsal","and","ventral","surfaces",",","to","form","the","mature","adult","wing","."),4103066). assertion_content_comment('oboGo_ImaginalDiscDerivedwinghairelongation',s("Growth","of","a","prehair","in","the","approximately","10","hour","period","following","its","emergence","from","an","epidermal","cell","in","an","imaginal","disc-derived","wing",".","Prehair","elongation","is","guided","and/or","driven","by","the","polymerization","of","actin","filaments","and","the","orderly","crosslinking","of","filaments","into","bundles","."),4071470). assertion_content_comment('oboGo_ImaginalDiscDerivedwinghairorganization',s("A","process","that","is","carried","out","at","the","cellular","level","that","results","in","the","assembly",",","arrangement","of","constituent","parts",",","or","disassembly","of","an","imaginal","disc-derived","wing","hair",".","A","wing","hair","is","an","actin-rich",",","polarized",",","non-sensory","apical","projection","that","protrudes","from","each","of","the","approximately","30",",","000","wing","epithelial","cells",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),3982576). assertion_content_comment('oboGo_ImaginalDiscDerivedwinghairoutgrowth',s("Extrusion","of","a","cellular","projection","from","the","apical","membrane","of","an","epithelial","cell","in","an","imaginal","disc-derived","wing",".","Outgrowth","initiates","approximately","35","hours","after","puparium","formation","from","the","distal","side","of","the","cell",",","and","at","this","stage","the","cellular","extension","is","termed","a","prehair","."),4071457). assertion_content_comment('oboGo_ImaginalDiscDerivedwinghairsiteselection',s("Determination","of","the","site","in","the","cell","of","an","imaginal","disc-derived","wing","at","which","a","prehair","initiates","outgrowth",".","Restriction","of","prehair","initiation","to","the","distalmost","part","of","a","cell","is","essential","to","ensure","that","each","wing","epithelial","cell","produces","one","adult","hair","that","points","distally","."),4071316). assertion_content_comment('oboGo_ImaginalDiscDerivedwingmarginmorphogenesis',s("The","process","in","which","the","anatomical","structures","of","the","imaginal","disc-derived","wing","margin","are","generated","and","organized",".","The","wing","margin","is","a","strip","of","cells","in","the","third","instar","disc","at","the","boundary","between","the","presumptive","dorsal","and","ventral","surfaces","of","the","wing","blade","."),4017959). assertion_content_comment('oboGo_ImaginalDiscDerivedwingmorphogenesis',s("The","process","in","which","the","anatomical","structures","of","the","imaginal","disc-derived","wing","are","generated","and","organized",".","The","wing","is","an","appendage","modified","for","flying","."),3982573). assertion_content_comment('oboGo_ImaginalDiscDerivedwingveinmorphogenesis',s("The","process","in","which","anatomical","structures","of","the","veins","on","an","imaginal","disc-derived","wing","are","generated","and","organized","."),4020249). assertion_content_comment('oboGo_ImaginalDiscDerivedwingveinspecification',s("The","regionalization","process","in","which","the","area","of","a","imaginal","disc-derived","wing","that","will","form","a","wing","vein","is","specified","."),4017981). assertion_content_comment('oboGo_Imidazoleacetate4Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","H","(","+",")","+","imidazol-4-ylacetate","+","NADH","+","O","(","2",")","=","5-hydroxyimidazole-4-acetate","+","H","(","2",")","O","+","NAD","(","+",")"),4374277). assertion_content_comment('oboGo_ImidazoleacetatePhosphoribosyldiphosphateligaseactivity',s("Catalysis","of","the","reaction",":","5-phospho-alpha-D-ribose","1-diphosphate","+","ATP","+","H","(","2",")","O","+","imidazol-4-ylacetate","=","1-","(","5-phosphoribosyl",")","imidazol-4-ylacetate","+","ADP","+","diphosphate","+","2","H","(","+",")","+","phosphate","."),4369789). assertion_content_comment('oboGo_ImidazoleglycerolPhosphatedehydrataseactivity',s("Catalysis","of","the","reaction",":","D-erythro-1-","(","imidazol-4-yl",")","glycerol","3-phosphate","=","3-","(","imidazol-4-yl",")","-2-oxopropyl","phosphate","+","H","(","2",")","O","."),4206782). assertion_content_comment('oboGo_ImidazoleglycerolPhosphatesynthaseactivity',s("Catalysis","of","the","reaction",":","phosphoribulosylformimino-AICAR-P","+","L-glutamine","=","D-erythro-imidazole-glycerol-phosphate","+","aminoimidazole","carboxamide","ribonucleotide","+","L-glutamate","+","2","H","+"),4345814). assertion_content_comment('oboGo_ImidazoleglycerolPhosphatesynthasecomplex',s("Complex","that","possesses","imidazoleglycerol-phosphate","synthase","activity","."),4260010). assertion_content_comment('oboGo_ImidazoleNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","1H-imidazole","+","acetyl-CoA","=","N-acetylimidazole","+","CoA","."),4374265). assertion_content_comment('oboGo_ImmuneResponseActivatingcellsurfacereceptorsignalingpathway',s("A","series","of","molecular","signals","initiated","by","the","binding","of","an","extracellular","ligand","to","a","receptor","on","the","surface","of","a","cell","capable","of","activating","or","perpetuating","an","immune","response","."),4052277). assertion_content_comment('oboGo_ImmuneResponseActivatingsignaltransduction',s("The","cascade","of","processes","by","which","a","signal","interacts","with","a","receptor",",","causing","a","change","in","the","level","or","activity","of","a","second","messenger","or","other","downstream","target",",","and","ultimately","leading","to","activation","or","perpetuation","of","an","immune","response","."),4052263). assertion_content_comment('oboGo_ImmuneResponseInGutAssociatedlymphoidtissue',s("Immune","response","taking","place","in","the","gut-associated","lymphoid","tissue","(","GALT",")","GALT","includes","Peyer","'","s","patches",",","appendix",",","and","solitary","lymph","nodules","."),4379348). assertion_content_comment('oboGo_ImmuneResponseInhibitingcellsurfacereceptorsignalingpathway',s("A","series","of","molecular","signals","initiated","by","the","binding","of","an","extracellular","ligand","to","a","receptor","on","the","surface","of","the","target","cell","capable","of","inhibiting","an","immune","response","."),4382392). assertion_content_comment('oboGo_ImmuneResponseInhibitingsignaltransduction',s("The","cascade","of","processes","by","which","a","signal","interacts","with","a","receptor",",","causing","a","change","in","the","level","or","activity","of","a","second","messenger","or","other","downstream","target",",","and","ultimately","leading","to","inhibition","of","an","immune","response","."),4083036). assertion_content_comment('oboGo_ImmuneResponseInMucosalAssociatedlymphoidtissue',s("Immune","response","taking","place","in","the","mucosal-associated","lymphoid","tissue","(","MALT",")","Mucosal-associated","lymphoid","tissue","is","typically","found","as","nodules","associated","with","mucosal","epithelia","with","distinct","internal","structures","including","B-","and","T-zones","for","the","activation","of","lymphocytes","."),3993410). assertion_content_comment('oboGo_ImmuneResponseInNasopharyngealAssociatedlymphoidtissue',s("An","immune","response","taking","place","in","the","nasopharyngeal-associated","lymphoid","tissue","(","NALT",")","NALT","includes","the","tonsils","and","adenoids","."),4379331). assertion_content_comment('oboGo_ImmuneResponseRegulatingcellsurfacereceptorsignalingpathway',s("A","series","of","molecular","signals","initiated","by","the","binding","of","an","extracellular","ligand","to","a","receptor","on","the","surface","of","the","target","cell","capable","of","activating",",","perpetuating",",","or","inhibiting","an","immune","response","."),4052274). assertion_content_comment('oboGo_ImmuneResponseRegulatingsignalingpathway',s("The","cascade","of","processes","by","which","a","signal","interacts","with","a","receptor",",","causing","a","change","in","the","level","or","activity","of","a","second","messenger","or","other","downstream","target",",","and","ultimately","leading","to","the","activation",",","perpetuation",",","or","inhibition","of","an","immune","response","."),4052260). assertion_content_comment('oboGo_ImmunoglobulinHeavyChainVDJrecombination',s("The","process","in","which","immunoglobulin","heavy","chain","V",",","D",",","and","J","gene","segments","are","recombined","within","a","single","locus","utilizing","the","conserved","heptamer","and","nonomer","recombination","signal","sequences","(","RSS",")"),4170303). assertion_content_comment('oboGo_ImmunoglobulinLightChainVJrecombination',s("The","process","in","which","immunoglobulin","light","chain","V","and","J","gene","segments","are","recombined","within","a","single","locus","utilizing","the","conserved","heptamer","and","nonomer","recombination","signal","sequences","(","RSS",")"),4170315). assertion_content_comment('oboGo_IMP5Nucleotidaseactivity',s("Catalysis","of","the","reaction",":","5","'","-IMP","+","H2O","=","inosine","+","phosphate","."),4266316). assertion_content_comment('oboGo_IMPGmpspecific5Nucleotidaseactivity',s("OBSOLETE",".","Catalysis","of","the","conversion","of","5","'","-ribonucleotides","to","ribonucleosides","and","phosphate",",","with","specificity","for","IMP","or","GMP","5","'","-ribonucleotides","and","H2O","as","a","nucleophile","."),4258247). assertion_content_comment('oboGo_ImportinAlphaexportreceptoractivity',s("Interacting","selectively","and","non-covalently","with","importin-alpha","to","mediate","its","transfer","through","the","nuclear","pore","to","the","cytoplasm","."),4256189). assertion_content_comment('oboGo_ImportinAlphaSubunitnuclearexportcomplex',s("A","protein","complex","which","usually","consists","of","three","components",",","e.g",".","in","Xenopus",",","the","importin","alpha-subunit/CAS/Ran",",","and","which","functions","to","shuttle","the","importin","alpha-subunit","out","of","the","nucleus","through","the","nuclear","pore","."),4316629). assertion_content_comment('oboGo_ImportinAlphaSubunit',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4220317). assertion_content_comment('oboGo_ImportinAlphaSubunittransportfactor',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4220187). assertion_content_comment('oboGo_ImportinBetaSubunit',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4220303). assertion_content_comment('oboGo_IncompatiblePollenPistilinteraction',s("OBSOLETE",".","An","interaction","between","a","pollen","grain","and","pistil","that","results","in","inhibition","of","pollen","germination/growth","."),4262636). assertion_content_comment('oboGo_Indol_3_Yl_Methyl_DesulfoglucosinolateSulfotransferaseActivity',s("Catalysis","of","the","reaction",":","indol-3-yl-methyl-desulfoglucosinolate","+","3","'","-phosphoadenosine","5","'","-phosphosulfate","=","indol-3-yl-methyl-glucosinolate","+","adenosine","3","'",",","5","'","-bisphosphate","."),4182743). assertion_content_comment('oboGo_Indole23Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","indole","+","O","(","2",")","=","2-formamidobenzaldehyde","."),4374300). assertion_content_comment('oboGo_Indole_3_AcetaldehydeOxidaseActivity',s("Catalysis","of","the","reaction",":","(","indol-3-yl",")","acetaldehyde","+","H","(","2",")","O","+","O","(","2",")","=","(","indol-3-yl",")","acetate","+","H","(","2",")","O","(","2",")","+","H","(","+",")"),4265802). assertion_content_comment('oboGo_Indole_3_AcetaldehydeReductaseNADHActivity',s("Catalysis","of","the","reaction",":","indole-3-ethanol","+","NAD","(","+",")","=","(","indol-3-yl",")","acetaldehyde","+","H","(","+",")","+","NADH","."),4364161). assertion_content_comment('oboGo_Indole_3_AcetaldehydeReductaseNADPHActivity',s("Catalysis","of","the","reaction",":","indole-3-ethanol","+","NADP","(","+",")","=","(","indol-3-yl",")","acetaldehyde","+","H","(","+",")","+","NADPH","."),4364120). assertion_content_comment('oboGo_Indole_3_AcetateBeta_GlucosyltransferaseActivity',s("Catalysis","of","the","reaction",":","(","indol-3-yl",")","acetate","+","UDP-D-glucose","=","1-O-","(","indol-3-ylacetyl",")","-beta-D-glucose","+","UDP","."),4366728). assertion_content_comment('oboGo_Indole_3_AceticAcidAmidoSynthetaseActivity',s("Catalysis","of","the","reaction",":","indole-3-acetic","acid","+","an","amino","acid","=","an","indole-3-acetic","acid","amide","conjugate","."),4335297). assertion_content_comment('oboGo_Indole_3_AcetonitrileNitrilaseActivity',s("Catalysis","of","the","reaction",":","indole-3-acetonitrile","+","2","H2O","=","indole-3-acetic","acid","+","NH3","."),4182594). assertion_content_comment('oboGo_Indole_3_AcetonitrileNitrileHydrataseActivity',s("Catalysis","of","the","reaction",":","indole-3-acetonitrile","+","H2O","=","indole-3-acetamide","."),4181451). assertion_content_comment('oboGo_Indole_3_ButyrateBeta_GlucosyltransferaseActivity',s("Catalysis","of","the","reaction",":","indole-3-butyrate","+","UDP-D-glucose","=","indole-3-butyryl-beta-1-D-glucose","+","UDP","."),4191528). assertion_content_comment('oboGo_Indole_3_Glycerol_PhosphateLyaseActivity',s("Catalysis","of","the","reaction",":","(","1S",",","2R",")","-1-C-","(","indol-3-yl",")","glycerol","3-phosphate","=","indole","+","D-glyceraldehyde","3-phosphate","."),4344924). assertion_content_comment('oboGo_Indole_3_Glycerol_PhosphateSynthaseActivity',s("Catalysis","of","the","reaction",":","1-","(","2-carboxyphenylamino",")","-1-deoxy-D-ribulose","5-phosphate","=","1-","(","indol-3-yl",")","glycerol","3-phosphate","+","CO2","+","H2O","."),4206796). assertion_content_comment('oboGo_IndoleacetateLysinesynthetaseactivity',s("Catalysis","of","the","reaction",":","(","indol-3-yl",")","acetate","+","L-lysine","+","ATP","=","N","(","6",")","-","[","(","indole-3-yl",")","acetyl","]","-L-lysine","+","ADP","+","2","H","(","+",")","+","phosphate","."),4374342). assertion_content_comment('oboGo_IndoleacetylglucoseInositoloAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","1-O-","(","indol-3-ylacetyl",")","-beta-D-glucose","+","myo-inositol","=","1L-1-O-","(","indol-3-yl",")","acetyl-myo-inositol","+","D-glucose","."),4366201). assertion_content_comment('oboGo_Indoleamine23Dioxygenaseactivity',s("Catalysis","of","the","reactions",":","tryptophan","+","O2","=","N-formylkynurenine",";","D-tryptophan","+","O2","=","N-formyl-D-kynurenine",";","and","L-tryptophan","+","O2","=","N-formyl-L-kynurenine","."),4342801). assertion_content_comment('oboGo_IndoleContainingcompoundbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","compounds","that","contain","an","indole","(","2",",","3-benzopyrrole",")","skeleton","."),4014197). assertion_content_comment('oboGo_IndoleContainingcompoundcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","compounds","that","contain","an","indole","(","2",",","3-benzopyrrole",")","skeleton","."),4232105). assertion_content_comment('oboGo_IndoleContainingcompoundmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","compounds","that","contain","an","indole","(","2",",","3-benzopyrrole",")","skeleton","."),4014050). assertion_content_comment('oboGo_IndolepyruvateCMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","indol-3-yl",")","pyruvate","=","S-adenosyl-L-homocysteine","+","(","S",")","-3-","(","indol-3-yl",")","-2-oxobutanoate","."),4308719). assertion_content_comment('oboGo_IndolylacetylMyoInositolgalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","1L-1-O-","(","indol-3-yl",")","acetyl-myo-inositol","+","UDP-D-galactose","=","5-O-","(","indol-3-ylacetyl",")","-myo-inositol","D-galactoside","+","H","(","+",")","+","UDP","."),4366529). assertion_content_comment('oboGo_IndoxylUdpgglucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","indoxyl","+","UDP-D-glucose","=","H","(","+",")","+","indican","+","UDP","."),4269662). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedcalciumionfluxinotherorganisminvolvedinsymbioticinteraction',s("The","activation","by","an","organism","of","a","flux","of","calcium","ions","that","occurs","as","part","of","the","defense","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4190649). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedcellwallthickeninginotherorganisminvolvedinsymbioticinteraction',s("The","activation","by","an","organism","of","the","thickening","of","cell","walls","that","occurs","as","part","of","the","defense","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4196294). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatednitricoxideproductioninotherorganisminvolvedinsymbioticinteraction',s("The","activation","by","an","organism","of","the","production","of","nitric","oxide","that","occurs","as","part","of","the","defense","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4195867). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedreactiveoxygenspeciesproductioninotherorganisminvolvedinsymbioticinteraction',s("The","activation","by","an","organism","of","the","production","of","reactive","oxygen","species","that","occurs","as","part","of","the","defense","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4195689). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedsymbiontcalciumionflux',s("OBSOLETE",".","The","activation","by","an","organism","of","a","flux","of","calcium","ions","that","occurs","as","part","of","the","defense","response","of","a","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190728). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedsymbiontcellwallthickening',s("OBSOLETE",".","Any","process","by","which","an","organism","activates",",","maintains","or","increases","the","frequency",",","rate","or","extent","of","symbiont","processes","resulting","in","the","thickening","of","its","cell","walls",",","occurring","as","part","of","the","defense","response","of","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190702). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedsymbiontnitricoxideproduction',s("OBSOLETE",".","The","activation","by","an","organism","of","the","production","of","nitric","oxide","as","part","of","the","defense","response","of","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190715). assertion_content_comment('oboGo_InductionByOrganismOfDefenseRelatedsymbiontreactiveoxygenspeciesproduction',s("OBSOLETE",".","The","activation","by","an","organism","of","the","production","of","reactive","oxygen","species","as","part","of","the","defense","response","of","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4188060). assertion_content_comment('oboGo_InductionByOrganismOfResistanceGeneDependentdefenseresponseofotherorganisminvolvedinsymbioticinteraction',s("The","activation","by","an","organism","of","the","resistance","gene-dependent","defense","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4196514). assertion_content_comment('oboGo_InductionByOrganismOfSymbiontNonApoptoticprogrammedcelldeath',s("OBSOLETE",".","Any","process","by","which","an","organism","activates","programmed","cell","death","in","the","symbiont",",","where","programmed","cell","death","proceeds","by","a","non-apoptotic","pathway",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190691). assertion_content_comment('oboGo_InductionByOrganismOfSymbiontResistanceGeneDependentdefenseresponse',s("OBSOLETE",".","The","activation","by","an","organism","of","the","resistance","gene-dependent","defense","response","of","the","symbiont","organism",".","The","symbiont","is","defined","as","the","smaller","of","the","organisms","involved","in","a","symbiotic","interaction","."),4188106). assertion_content_comment('oboGo_InductionBySymbiontOfDefenseRelatedhostcalciumionflux',s("The","activation","by","an","organism","of","a","flux","of","calcium","ions","that","occurs","as","part","of","the","defense","response","of","a","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4190656). 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assertion_content_comment('oboGo_InsulinLikegrowthfactorbinding',s("Interacting","selectively","and","non-covalently","with","an","insulin-like","growth","factor",",","any","member","of","a","group","of","polypeptides","that","are","structurally","homologous","to","insulin","and","share","many","of","its","biological","activities",",","but","are","immunologically","distinct","from","it","."),4218787). assertion_content_comment('oboGo_InsulinLikegrowthfactoribinding',s("Interacting","selectively","and","non-covalently","with","insulin-like","growth","factor","I","."),4320607). assertion_content_comment('oboGo_InsulinLikegrowthfactoriibinding',s("Interacting","selectively","and","non-covalently","with","insulin-like","growth","factor","II","."),4320556). assertion_content_comment('oboGo_InsulinLikegrowthfactorreceptoractivity',s("Combining","with","an","insulin-like","growth","factor","to","initiate","a","change","in","cell","activity","."),4214011). assertion_content_comment('oboGo_InsulinLikegrowthfactorreceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","insulin-like","growth","factor","receptor","."),4217223). assertion_content_comment('oboGo_InsulinLikegrowthfactorreceptorsignalingpathway',s("The","series","of","molecular","signals","generated","as","a","consequence","of","the","insulin-like","growth","factor","receptor","binding","to","one","of","its","physiological","ligands","."),4094846). assertion_content_comment('oboGo_InsulinLikegrowthfactorternarycomplex',s("A","complex","of","three","proteins",",","which","in","animals","is","approximately","150kDa","and","consists","of","the","insulin-like","growth","factor","(","IGF",")",",","the","insulin-like","growth","factor","binding","protein-3","(","IGFBP-3",")",",","or","-5","(","IGFBP-5",")","and","an","acid-labile","subunit","(","ALS",")","The","complex","plays","a","role","in","growth","and","development","."),4316744). assertion_content_comment('oboGo_InsulinResponsivecompartment',s("A","small","membrane-bounded","vesicle","that","releases","its","contents","by","exocytosis","in","response","to","insulin","stimulation",";","the","contents","are","enriched","in","GLUT4",",","IRAP","and","VAMP2","."),4331632). assertion_content_comment('oboGo_InsulinResponsivehydrogen_Glucosesymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glucose","+","H","+","=","glucose","+","H","+",",","in","response","to","a","stimulus","by","insulin",".","Symporter","activity","enables","the","active","transport","of","a","solute","across","a","membrane","by","a","mechanism","whereby","two","or","more","species","are","transported","together","in","the","same","direction","in","a","tightly","coupled","process","not","directly","linked","to","a","form","of","energy","other","than","chemiosmotic","energy","."),4216597). assertion_content_comment('oboGo_IntegralToFungalTypevacuolarmembrane',s("Located","such","that","some","or","all","of","the","gene","product","itself","penetrates","at","least","one","phospholipid","bilayer","of","the","fungal-type","vacuolar","membrane",".","May","also","refer","to","the","state","of","being","buried","in","the","bilayer","with","no","exposure","outside","the","bilayer","."),4172855). assertion_content_comment('oboGo_IntegrinMediatedsignalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","an","integrin","binding","to","one","of","its","physiological","ligands","."),4235695). assertion_content_comment('oboGo_InteinMediatedproteinsplicing',s("The","removal","of","an","internal","amino","acid","sequence","(","an","intein",")","from","a","protein","during","protein","maturation",";","the","excision","of","inteins","is","precise","and","the","N-","and","C-terminal","exteins","are","joined","by","a","normal","peptide","bond",".","Protein","splicing","involves","4","nucleophilic","displacements","by","the","3","conserved","splice","junction","residues","."),4042341). assertion_content_comment('oboGo_InteractionWithHostMediatedBySymbiontSecretedSubstanceReleasedFromSymbiontContainingvacuole',s("An","interaction","with","the","host","organism","mediated","by","a","substance","released","by","the","other","(","symbiont",")","organism","via","a","symbiont-containing","vacuole",",","a","specialized","sac","within","the","host","in","which","the","symbiont","resides",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4080531). assertion_content_comment('oboGo_IntercellularAdhesionMolecule_3ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","receptors","for","intercellular","adhesion","molecule-3","(","ICAM-3",")",",","such","as","DC-SIGN","and","LFA-1","."),4309762). assertion_content_comment('oboGo_InterferonAlphabetareceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","interferon-alpha/beta","receptor","."),4214578). assertion_content_comment('oboGo_InterferonAlphabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interferon-alpha","."),4085961). assertion_content_comment('oboGo_InterferonAlphaproduction',s("The","appearance","of","interferon-alpha","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067059). assertion_content_comment('oboGo_InterferonAlphasecretion',s("The","regulated","release","of","interferon-alpha","from","a","cell","or","group","of","cells","."),4126200). assertion_content_comment('oboGo_InterferonBetabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interferon-beta","."),4084702). assertion_content_comment('oboGo_InterferonBetaproduction',s("The","appearance","of","interferon-beta","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067037). assertion_content_comment('oboGo_InterferonBetasecretion',s("The","regulated","release","of","interferon-beta","from","a","cell","or","group","of","cells","."),4083595). assertion_content_comment('oboGo_InterferonDeltaproduction',s("The","appearance","of","interferon-delta","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4146792). assertion_content_comment('oboGo_InterferonDeltasecretion',s("The","regulated","release","of","interferon-delta","from","a","cell","or","group","of","cells","."),4146804). assertion_content_comment('oboGo_InterferonEpsilonproduction',s("The","appearance","of","interferon-epsilon","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4146769). assertion_content_comment('oboGo_InterferonEpsilonsecretion',s("The","regulated","release","of","interferon-epsilon","from","a","cell","or","group","of","cells","."),4146781). assertion_content_comment('oboGo_InterferonGammabinding',s("Interacting","selectively","and","non-covalently","with","interferon-gamma",".","Interferon-gamma","is","also","known","as","type","II","interferon","."),4198266). assertion_content_comment('oboGo_InterferonGammabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interferon-gamma","."),4080816). assertion_content_comment('oboGo_InterferonGammaMediatedsignalingpathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","interferon-gamma","binding","to","a","cell","surface","receptor","."),4114622). assertion_content_comment('oboGo_InterferonGammaproduction',s("The","appearance","of","interferon-gamma","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels",".","Interferon-gamma","is","also","known","as","type","II","interferon","."),4067122). assertion_content_comment('oboGo_InterferonGammareceptoractivity',s("Combining","with","interferon-gamma","to","initiate","a","change","in","cell","activity",".","Interferon-gamma","is","also","known","as","type","II","interferon","."),4198271). assertion_content_comment('oboGo_InterferonGammareceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","interferon-gamma","receptor","."),4214567). assertion_content_comment('oboGo_InterferonGammasecretion',s("The","regulated","release","of","interferon-gamma","from","a","cell","or","group","of","cells","."),4126212). assertion_content_comment('oboGo_InterferonKappaproduction',s("The","appearance","of","interferon-kappa","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4146746). assertion_content_comment('oboGo_InterferonKappasecretion',s("The","regulated","release","of","interferon-kappa","from","a","cell","or","group","of","cells","."),4146758). assertion_content_comment('oboGo_InterferonOmegaproduction',s("The","appearance","of","interferon-omega","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4146877). assertion_content_comment('oboGo_InterferonOmegasecretion',s("The","regulated","release","of","interferon-omega","from","a","cell","or","group","of","cells","."),4146889). assertion_content_comment('oboGo_InterferonTauproduction',s("The","appearance","of","interferon-tau","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4146723). assertion_content_comment('oboGo_InterferonTausecretion',s("The","regulated","release","of","interferon-tau","from","a","cell","or","group","of","cells","."),4146735). assertion_content_comment('oboGo_InterGolgicisternavesicleMediatedtransport',s("The","directed","movement","of","substances","from","one","Golgi","cisterna","to","another",",","mediated","by","small","transport","vesicles","."),4025448). assertion_content_comment('oboGo_InterGolgitransportvesiclemembrane',s("The","lipid","bilayer","surrounding","a","vesicle","transporting","substances","within","the","Golgi","."),4036056). assertion_content_comment('oboGo_InterGolgitransportvesicle',s("A","vesicle","that","mediates","transport","of","cargo","within","the","Golgi","complex","(","for","example",",","between","cisternae","of","the","Golgi","stack",")"),4036001). assertion_content_comment('oboGo_Interleukin_10Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-10","."),4198759). assertion_content_comment('oboGo_Interleukin_10BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-10","."),4080666). assertion_content_comment('oboGo_Interleukin_10Production',s("The","appearance","of","interleukin-10","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067187). assertion_content_comment('oboGo_Interleukin_10ReceptorActivity',s("Combining","with","interleukin-10","to","initiate","a","change","in","cell","activity","."),4198762). assertion_content_comment('oboGo_Interleukin_10ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-10","receptor","."),4214424). assertion_content_comment('oboGo_Interleukin_10Secretion',s("The","regulated","release","of","interleukin-10","from","a","cell","or","group","of","cells","."),4126690). assertion_content_comment('oboGo_Interleukin_11Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-11","."),4198782). assertion_content_comment('oboGo_Interleukin_11BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-11","."),4079488). assertion_content_comment('oboGo_Interleukin_11Production',s("The","appearance","of","interleukin-11","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067166). assertion_content_comment('oboGo_Interleukin_11ReceptorActivity',s("Combining","with","interleukin-11","to","initiate","a","change","in","cell","activity","."),4198785). assertion_content_comment('oboGo_Interleukin_11ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-11","receptor","."),4214412). assertion_content_comment('oboGo_Interleukin_11Secretion',s("The","regulated","release","of","interleukin-11","from","a","cell","or","group","of","cells","."),4126455). assertion_content_comment('oboGo_Interleukin_12AlphaSubunitBinding',s("Interacting","selectively","and","non-covalently","with","the","alpha","subunit","of","interleukin-12","."),4313468). assertion_content_comment('oboGo_Interleukin_12BetaSubunitBinding',s("Interacting","selectively","and","non-covalently","with","the","beta","subunit","of","interleukin-12","."),4313481). assertion_content_comment('oboGo_Interleukin_12Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-12","."),4233141). assertion_content_comment('oboGo_Interleukin_12BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-12","."),4080641). assertion_content_comment('oboGo_Interleukin_12Complex',s("A","protein","complex","that","is","composed","of","an","interleukin-12","alpha","(","p35",",","product","of","the","IL12A","gene",")","and","an","interleukin-12","beta","subunit","(","p40",",","product","of","the","IL12B","gene",")","and","is","secreted","into","the","extracellular","space","."),4094598). assertion_content_comment('oboGo_Interleukin_12_Interleukin_12ReceptorComplex',s("A","protein","complex","that","is","formed","by","the","association","of","a","heterodimeric","interleukin-12","receptor","complex","with","an","interleukin-12","heterodimer","."),4180457). assertion_content_comment('oboGo_Interleukin_12_MediatedSignalingPathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","interleukin-12","binding","to","a","cell","surface","receptor","."),4380943). assertion_content_comment('oboGo_Interleukin_12Production',s("The","appearance","of","interleukin-12","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067229). assertion_content_comment('oboGo_Interleukin_12ReceptorActivity',s("Combining","with","interleukin-12","to","initiate","a","change","in","cell","activity","."),4305360). assertion_content_comment('oboGo_Interleukin_12ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-12","receptor","."),4214481). assertion_content_comment('oboGo_Interleukin_12ReceptorComplex',s("A","protein","complex","that","binds","interleukin-12",";","comprises","a","beta1","and","a","beta2","subunit","."),4081560). assertion_content_comment('oboGo_Interleukin_12Secretion',s("The","regulated","release","of","interleukin-12","from","a","cell","or","group","of","cells","."),4126466). assertion_content_comment('oboGo_Interleukin_13Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-13","."),4233121). assertion_content_comment('oboGo_Interleukin_13BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-13","."),4079472). assertion_content_comment('oboGo_Interleukin_13_MediatedSignalingPathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","interleukin-13","binding","to","a","cell","surface","receptor","."),4381154). assertion_content_comment('oboGo_Interleukin_13Production',s("The","appearance","of","interleukin-13","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067208). assertion_content_comment('oboGo_Interleukin_13ReceptorActivity',s("Combining","with","interleukin-13","to","initiate","a","change","in","cell","activity","."),4305338). assertion_content_comment('oboGo_Interleukin_13ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-13","receptor","."),4214469). assertion_content_comment('oboGo_Interleukin_13ReceptorComplex',s("A","protein","complex","that","binds","interleukin-13",";","consists","of","two","chains",",","interleukin-13","receptor","alpha1","chain","and","interleukin-4","receptor","alpha","chain","."),4008245). assertion_content_comment('oboGo_Interleukin_13Secretion',s("The","regulated","release","of","interleukin-13","from","a","cell","or","group","of","cells","."),4126481). assertion_content_comment('oboGo_Interleukin_14Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-14","."),4233131). assertion_content_comment('oboGo_Interleukin_14BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-14","."),4079456). assertion_content_comment('oboGo_Interleukin_14Production',s("The","appearance","of","interleukin-14","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067271). assertion_content_comment('oboGo_Interleukin_14ReceptorActivity',s("Combining","with","interleukin-14","to","initiate","a","change","in","cell","activity","."),4305209). assertion_content_comment('oboGo_Interleukin_14ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-14","receptor","."),4214458). assertion_content_comment('oboGo_Interleukin_14Secretion',s("The","regulated","release","of","interleukin-14","from","a","cell","or","group","of","cells","."),4126419). assertion_content_comment('oboGo_Interleukin_15Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-15","."),4306127). assertion_content_comment('oboGo_Interleukin_15BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-15","."),4079440). assertion_content_comment('oboGo_Interleukin_15_MediatedSignalingPathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","interleukin-15","binding","to","a","cell","surface","receptor","."),4380931). assertion_content_comment('oboGo_Interleukin_15Production',s("The","appearance","of","interleukin-15","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067250). assertion_content_comment('oboGo_Interleukin_15ReceptorActivity',s("Combining","with","interleukin-15","to","initiate","a","change","in","cell","activity","."),4306213). assertion_content_comment('oboGo_Interleukin_15ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-15","receptor","."),4304113). assertion_content_comment('oboGo_Interleukin_15Secretion',s("The","regulated","release","of","interleukin-15","from","a","cell","or","group","of","cells","."),4126430). assertion_content_comment('oboGo_Interleukin_16Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-16","."),4306176). assertion_content_comment('oboGo_Interleukin_16BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-16","."),4079424). assertion_content_comment('oboGo_Interleukin_16Production',s("The","appearance","of","interleukin-16","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068615). assertion_content_comment('oboGo_Interleukin_16ReceptorActivity',s("Combining","with","interleukin-16","to","initiate","a","change","in","cell","activity","."),4306179). assertion_content_comment('oboGo_Interleukin_16ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-16","receptor","."),4299156). assertion_content_comment('oboGo_Interleukin_16Secretion',s("The","regulated","release","of","interleukin-16","from","a","cell","or","group","of","cells","."),4126441). assertion_content_comment('oboGo_Interleukin_17Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-17","."),4233161). assertion_content_comment('oboGo_Interleukin_17BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-17","."),4079408). assertion_content_comment('oboGo_Interleukin_17EReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-17E","receptor","."),4309467). assertion_content_comment('oboGo_Interleukin_17Production',s("The","appearance","of","interleukin-17","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068594). assertion_content_comment('oboGo_Interleukin_17ReceptorActivity',s("Combining","with","interleukin-17","to","initiate","a","change","in","cell","activity","."),4309691). assertion_content_comment('oboGo_Interleukin_17ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-17","receptor","."),4309679). assertion_content_comment('oboGo_Interleukin_17Secretion',s("The","regulated","release","of","interleukin-17","from","a","cell","or","group","of","cells","."),4126530). assertion_content_comment('oboGo_Interleukin_18AlphaSubunitBinding',s("Interacting","selectively","and","non-covalently","with","the","alpha","subunit","of","interleukin-18",".","IL-18a","is","a","component","of","IL-18","that","is","essential","for","IL-18","binding","on","the","surface","of","T-helper","1","cells","."),4301140). assertion_content_comment('oboGo_Interleukin_18BetaSubunitBinding',s("Interacting","selectively","and","non-covalently","with","the","beta","subunit","of","interleukin-18",".","IL-18b","is","a","ligand","non-binding","chain","and","is","required","for","signaling","of","IL-18","that","binds","with","IL-18a","."),4301150). assertion_content_comment('oboGo_Interleukin_18Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-18","."),4301137). assertion_content_comment('oboGo_Interleukin_18BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-18","."),4079298). assertion_content_comment('oboGo_Interleukin_18_MediatedSignalingPathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","interleukin-18","binding","to","a","cell","surface","receptor","."),4145529). assertion_content_comment('oboGo_Interleukin_18Production',s("The","appearance","of","interleukin-18","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068573). assertion_content_comment('oboGo_Interleukin_18ReceptorActivity',s("Combining","with","interleukin-18","to","initiate","a","change","in","cell","activity","."),4306147). assertion_content_comment('oboGo_Interleukin_18ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-18","receptor","."),4299167). assertion_content_comment('oboGo_Interleukin_18ReceptorComplex',s("A","protein","complex","that","binds","interleukin-18",";","comprises","an","alpha","and","a","beta","subunit","."),4086359). assertion_content_comment('oboGo_Interleukin_18Secretion',s("The","regulated","release","of","interleukin-18","from","a","cell","or","group","of","cells","."),4126545). assertion_content_comment('oboGo_Interleukin_19Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-19","."),4306158). assertion_content_comment('oboGo_Interleukin_19BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-19","."),4079392). assertion_content_comment('oboGo_Interleukin_19Production',s("The","appearance","of","interleukin-19","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068049). assertion_content_comment('oboGo_Interleukin_19ReceptorActivity',s("Combining","with","interleukin-19","to","initiate","a","change","in","cell","activity","."),4306201). assertion_content_comment('oboGo_Interleukin_19ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-19","receptor","."),4299178). assertion_content_comment('oboGo_Interleukin_19Secretion',s("The","regulated","release","of","interleukin-19","from","a","cell","or","group","of","cells","."),4126558). assertion_content_comment('oboGo_Interleukin_1AlphaBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-1","alpha","."),4101525). assertion_content_comment('oboGo_Interleukin_1AlphaProduction',s("The","appearance","of","interleukin-1","alpha","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067090). assertion_content_comment('oboGo_Interleukin_1AlphaSecretion',s("The","regulated","release","of","interleukin-1","alpha","from","a","cell","or","group","of","cells","."),4101661). assertion_content_comment('oboGo_Interleukin_1BetaBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-1","beta","."),4101573). assertion_content_comment('oboGo_Interleukin_1BetaProduction',s("The","appearance","of","interleukin-1","beta","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067145). assertion_content_comment('oboGo_Interleukin_1BetaSecretion',s("The","regulated","release","of","interleukin","1","beta","from","a","cell","or","group","of","cells","."),4101728). assertion_content_comment('oboGo_Interleukin_1Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-1","."),4198216). assertion_content_comment('oboGo_Interleukin_1BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-1",",","an","interleukin","produced","mainly","by","activated","macrophages",".","It","is","involved","in","the","inflammatory","response",",","and","is","identified","as","an","endogenous","pyrogen","."),4080990). assertion_content_comment('oboGo_Interleukin_1_MediatedSignalingPathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","interleukin-1","binding","to","a","cell","surface","receptor","."),4175730). assertion_content_comment('oboGo_Interleukin_1Production',s("The","appearance","of","interleukin-1","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067087). assertion_content_comment('oboGo_Interleukin_1ReceptorActivity',s("Combining","with","interleukin-1","to","initiate","a","change","in","cell","activity",".","Interleukin-1","is","produced","mainly","by","activated","macrophages","and","is","involved","in","the","inflammatory","response","."),4198219). assertion_content_comment('oboGo_Interleukin_1ReceptorAntagonistActivity',s("Blocks","the","binding","of","interleukin-1","to","the","interleukin-1","receptor","complex","."),4217498). assertion_content_comment('oboGo_Interleukin_1ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-1","receptor","."),4214378). assertion_content_comment('oboGo_Interleukin_1ReceptorComplex',s("A","protein","complex","that","binds","interleukin-1",";","comprises","an","alpha","and","a","beta","subunit","."),4085802). assertion_content_comment('oboGo_Interleukin_1Secretion',s("The","regulated","release","of","interleukin-1","from","a","cell","or","group","of","cells",".","Interleukin","1","is","produced","mainly","by","activated","macrophages",";","it","stimulates","thymocyte","proliferation","by","inducing","interleukin","2","release","and","it","is","involved","in","the","inflammatory","response","."),4101340). assertion_content_comment('oboGo_Interleukin_1TypeIActivatingReceptorActivity',s("Combining","with","interleukin-1","to","initiate","a","change","in","cell","activity","via","signaling","pathways","and","mediated","by","adaptor","proteins","."),4198223). assertion_content_comment('oboGo_Interleukin_1TypeIIBlockingReceptorActivity',s("Combining","with","interleukin-1","to","initiate","a","change","in","cell","activity","by","inhibiting","the","activity","of","type","I","interleukin","receptors","."),4198389). assertion_content_comment('oboGo_Interleukin_1TypeIIReceptorAntagonistActivity',s("Blocks","the","binding","of","interleukin-1","to","interleukin-1","Type","II","receptors","."),4298441). assertion_content_comment('oboGo_Interleukin_1TypeIIReceptorBinding',s("Interacting","selectively","and","non-covalently","with","a","Type","II","interleukin-1","receptor","."),4217429). assertion_content_comment('oboGo_Interleukin_1TypeIReceptorAntagonistActivity',s("Blocks","the","binding","of","interleukin-1","to","interleukin-1","Type","I","receptors","."),4298451). assertion_content_comment('oboGo_Interleukin_1TypeIReceptorBinding',s("Interacting","selectively","and","non-covalently","with","a","Type","I","interleukin-1","receptor","."),4217440). assertion_content_comment('oboGo_Interleukin_20Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-20","."),4306190). assertion_content_comment('oboGo_Interleukin_20BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-20","."),4079376). assertion_content_comment('oboGo_Interleukin_20Production',s("The","appearance","of","interleukin-20","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068123). assertion_content_comment('oboGo_Interleukin_20ReceptorActivity',s("Combining","with","interleukin-20","to","initiate","a","change","in","cell","activity","."),4306257). assertion_content_comment('oboGo_Interleukin_20ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-20","receptor","."),4299189). assertion_content_comment('oboGo_Interleukin_20ReceptorComplex',s("A","protein","complex","that","binds","interleukin-20",";","comprises","an","alpha","and","a","beta","subunit","."),4061829). assertion_content_comment('oboGo_Interleukin_20Secretion',s("The","regulated","release","of","interleukin-20","from","a","cell","or","group","of","cells","."),4126492). assertion_content_comment('oboGo_Interleukin_21Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-21","."),4233151). assertion_content_comment('oboGo_Interleukin_21BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-21","."),4079360). assertion_content_comment('oboGo_Interleukin_21Production',s("The","appearance","of","interleukin-21","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068086). assertion_content_comment('oboGo_Interleukin_21ReceptorActivity',s("Combining","with","interleukin-21","to","initiate","a","change","in","cell","activity","."),4361616). assertion_content_comment('oboGo_Interleukin_21ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-21","receptor","."),4361647). assertion_content_comment('oboGo_Interleukin_21Secretion',s("The","regulated","release","of","interleukin-21","from","a","cell","or","group","of","cells","."),4126504). assertion_content_comment('oboGo_Interleukin_22Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-22","."),4306232). assertion_content_comment('oboGo_Interleukin_22BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-22","."),4079328). assertion_content_comment('oboGo_Interleukin_22Production',s("The","appearance","of","interleukin-22","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067901). assertion_content_comment('oboGo_Interleukin_22ReceptorActivity',s("Combining","with","interleukin-22","to","initiate","a","change","in","cell","activity","."),4306235). assertion_content_comment('oboGo_Interleukin_22ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-22","receptor","."),4299134). assertion_content_comment('oboGo_Interleukin_22Secretion',s("The","regulated","release","of","interleukin-22","from","a","cell","or","group","of","cells","."),4126516). assertion_content_comment('oboGo_Interleukin_23Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-23","."),4306246). assertion_content_comment('oboGo_Interleukin_23BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-23","."),4079344). assertion_content_comment('oboGo_Interleukin_23Complex',s("A","protein","complex","that","is","composed","of","an","interleukin-23","alpha","(","p19",",","product","of","the","IL23A","gene",")","and","an","interleukin-12","beta","(","p40",",","product","of","the","IL12B","gene",")","subunit","and","is","secreted","into","the","extracellular","space","."),4130371). assertion_content_comment('oboGo_Interleukin_23Production',s("The","appearance","of","interleukin-23","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067864). assertion_content_comment('oboGo_Interleukin_23ReceptorActivity',s("Combining","with","interleukin-23","to","initiate","a","change","in","cell","activity","."),4306281). assertion_content_comment('oboGo_Interleukin_23ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-23","receptor","."),4299145). assertion_content_comment('oboGo_Interleukin_23ReceptorComplex',s("A","protein","complex","that","binds","interleukin-23",".","The","complex","comprises","two","subunits",",","including","the","same","beta","subunit","found","in","the","interleukin-12","receptor","."),4126050). assertion_content_comment('oboGo_Interleukin_23Secretion',s("The","regulated","release","of","interleukin-23","from","a","cell","or","group","of","cells","."),4126331). assertion_content_comment('oboGo_Interleukin_24Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-24","."),4299230). assertion_content_comment('oboGo_Interleukin_24BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-24","."),4088927). assertion_content_comment('oboGo_Interleukin_24Production',s("The","appearance","of","interleukin-24","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067975). assertion_content_comment('oboGo_Interleukin_24ReceptorActivity',s("Combining","with","interleukin-24","to","initiate","a","change","in","cell","activity","."),4299286). assertion_content_comment('oboGo_Interleukin_24ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-24","receptor","."),4299123). assertion_content_comment('oboGo_Interleukin_24Secretion',s("The","regulated","release","of","interleukin-24","from","a","cell","or","group","of","cells","."),4126317). assertion_content_comment('oboGo_Interleukin_25Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-25","."),4299220). assertion_content_comment('oboGo_Interleukin_25BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-25","."),4088641). assertion_content_comment('oboGo_Interleukin_25Production',s("The","appearance","of","interleukin-25","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067938). assertion_content_comment('oboGo_Interleukin_25ReceptorActivity',s("Combining","with","interleukin-25","to","initiate","a","change","in","cell","activity","."),4299253). assertion_content_comment('oboGo_Interleukin_25ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-25","receptor","."),4299101). assertion_content_comment('oboGo_Interleukin_25Secretion',s("The","regulated","release","of","interleukin-25","from","a","cell","or","group","of","cells","."),4126304). assertion_content_comment('oboGo_Interleukin_26Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-26","."),4299210). assertion_content_comment('oboGo_Interleukin_26BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-26","."),4088586). assertion_content_comment('oboGo_Interleukin_26Production',s("The","appearance","of","interleukin-26","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067753). assertion_content_comment('oboGo_Interleukin_26ReceptorActivity',s("Combining","with","interleukin-26","to","initiate","a","change","in","cell","activity","."),4299265). assertion_content_comment('oboGo_Interleukin_26ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-26","receptor","."),4299090). assertion_content_comment('oboGo_Interleukin_26Secretion',s("The","regulated","release","of","interleukin-26","from","a","cell","or","group","of","cells","."),4126291). assertion_content_comment('oboGo_Interleukin_27Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-27","."),4299200). assertion_content_comment('oboGo_Interleukin_27BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-27","."),4088696). assertion_content_comment('oboGo_Interleukin_27Complex',s("A","protein","complex","that","is","composed","of","an","interleukin-27p28","subunit","(","product","of","the","IL27","gene",")","and","an","EBI3","subunit","and","is","secreted","into","the","extracellular","space","."),4130388). assertion_content_comment('oboGo_Interleukin_27_MediatedSignalingPathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","interleukin-27","binding","to","a","cell","surface","receptor","."),4132940). assertion_content_comment('oboGo_Interleukin_27Production',s("The","appearance","of","interleukin-27","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067716). assertion_content_comment('oboGo_Interleukin_27ReceptorActivity',s("Combining","with","interleukin-27","to","initiate","a","change","in","cell","activity","."),4299241). assertion_content_comment('oboGo_Interleukin_27ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-27","receptor","."),4299112). assertion_content_comment('oboGo_Interleukin_27Secretion',s("The","regulated","release","of","interleukin-27","from","a","cell","or","group","of","cells","."),4126278). assertion_content_comment('oboGo_Interleukin_28AProduction',s("The","appearance","of","interleukin-28A","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126393). assertion_content_comment('oboGo_Interleukin_28ASecretion',s("The","regulated","release","of","interleukin-28A","from","a","cell","or","group","of","cells","."),4126406). assertion_content_comment('oboGo_Interleukin_28BProduction',s("The","appearance","of","interleukin-28B","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126368). assertion_content_comment('oboGo_Interleukin_28BSecretion',s("The","regulated","release","of","interleukin-28B","from","a","cell","or","group","of","cells","."),4126381). assertion_content_comment('oboGo_Interleukin_28ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-28","receptor","."),4330612). assertion_content_comment('oboGo_Interleukin_28ReceptorComplex',s("A","protein","complex","that","binds","interleukin-28","and","interleukin-29",".","Composed","of","two","subunits",",","IL-28R","alpha","and","IL-10R","beta","."),4057861). assertion_content_comment('oboGo_Interleukin_29Production',s("The","appearance","of","interleukin-29","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126343). assertion_content_comment('oboGo_Interleukin_29Secretion',s("The","regulated","release","of","interleukin-29","from","a","cell","or","group","of","cells","."),4126356). assertion_content_comment('oboGo_Interleukin_2Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-2","."),4198351). assertion_content_comment('oboGo_Interleukin_2BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-2","."),4080800). assertion_content_comment('oboGo_Interleukin_2Production',s("The","appearance","of","interleukin-2","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068012). assertion_content_comment('oboGo_Interleukin_2ReceptorActivity',s("Combining","with","interleukin-2","to","initiate","a","change","in","cell","activity","."),4198354). assertion_content_comment('oboGo_Interleukin_2ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-2","receptor","."),4214602). assertion_content_comment('oboGo_Interleukin_2ReceptorComplex',s("A","protein","complex","that","binds","interleukin-2",";","comprises","alpha",",","beta",",","and","gamma","subunits","."),4008339). assertion_content_comment('oboGo_Interleukin_2Secretion',s("The","regulated","release","of","interleukin-2","from","a","cell","or","group","of","cells","."),4131565). assertion_content_comment('oboGo_Interleukin_30Production',s("The","appearance","of","interleukin-30","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126165). assertion_content_comment('oboGo_Interleukin_30Secretion',s("The","regulated","release","of","interleukin-30","from","a","cell","or","group","of","cells","."),4126177). assertion_content_comment('oboGo_Interleukin_31Production',s("The","appearance","of","interleukin-31","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126144). assertion_content_comment('oboGo_Interleukin_31Secretion',s("The","regulated","release","of","interleukin-31","from","a","cell","or","group","of","cells","."),4126155). assertion_content_comment('oboGo_Interleukin_32Production',s("The","appearance","of","interleukin-32","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126117). assertion_content_comment('oboGo_Interleukin_32Secretion',s("The","regulated","release","of","interleukin-32","from","a","cell","or","group","of","cells","."),4126131). assertion_content_comment('oboGo_Interleukin_33Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-33","."),4374575). assertion_content_comment('oboGo_Interleukin_33Production',s("The","appearance","of","interleukin-33","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126225). assertion_content_comment('oboGo_Interleukin_33ReceptorActivity',s("Combining","with","interleukin-33","to","initiate","a","change","in","cell","activity","."),4374579). assertion_content_comment('oboGo_Interleukin_33ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-33","receptor","."),4374590). assertion_content_comment('oboGo_Interleukin_33Secretion',s("The","regulated","release","of","interleukin-33","from","a","cell","or","group","of","cells","."),4126240). assertion_content_comment('oboGo_Interleukin_35Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-35","."),4176098). assertion_content_comment('oboGo_Interleukin_35BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-35","."),4130288). assertion_content_comment('oboGo_Interleukin_35Complex',s("A","protein","complex","that","is","composed","of","an","interleukin-12","alpha","subunit","(","p35",",","product","of","the","IL12A","gene",")","and","an","EBI3","subunit","and","is","secreted","into","the","extracellular","space","."),4130355). assertion_content_comment('oboGo_Interleukin_35_MediatedSignalingPathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","interleukin-35","binding","to","a","cell","surface","receptor","."),4132807). assertion_content_comment('oboGo_Interleukin_35Production',s("The","appearance","of","interleukin-35","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4126254). assertion_content_comment('oboGo_Interleukin_35ReceptorActivity',s("Combining","with","interleukin-35","to","initiate","a","change","in","cell","activity","."),4176131). assertion_content_comment('oboGo_Interleukin_35ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-35","receptor","."),4176119). assertion_content_comment('oboGo_Interleukin_35Secretion',s("The","regulated","release","of","interleukin-35","from","a","cell","or","group","of","cells","."),4126265). assertion_content_comment('oboGo_Interleukin_3Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-3","."),4198374). assertion_content_comment('oboGo_Interleukin_3BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-3","."),4080974). assertion_content_comment('oboGo_Interleukin_3Production',s("The","appearance","of","interleukin-3","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067827). assertion_content_comment('oboGo_Interleukin_3ReceptorActivity',s("Combining","with","interleukin-3","to","initiate","a","change","in","cell","activity","."),4198377). assertion_content_comment('oboGo_Interleukin_3ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-3","receptor","."),4214590). assertion_content_comment('oboGo_Interleukin_3ReceptorComplex',s("A","protein","complex","that","binds","interleukin-3",";","comprises","an","alpha","and","a","beta","subunit",".","The","alpha","chain","is","specific","to","the","interleukin-3","receptor",",","whereas","the","beta","chain","is","shared","with","the","receptors","for","granulocyte-macrophage","colony-stimulating","factor","and","interleukin-5","."),4008327). assertion_content_comment('oboGo_Interleukin_3Secretion',s("The","regulated","release","of","interleukin-3","from","a","cell","or","group","of","cells","."),4126712). assertion_content_comment('oboGo_Interleukin_4Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-4","."),4198624). assertion_content_comment('oboGo_Interleukin_4BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-4","."),4080877). assertion_content_comment('oboGo_Interleukin_4_DependentIsotypeSwitchingToIgEIsotypes',s("The","switching","of","activated","B","cells","from","IgM","biosynthesis","to","IgE","biosynthesis",",","accomplished","through","a","recombination","process","involving","an","intrachromosomal","deletion","between","switch","regions","that","reside","5","'","of","the","IgM","and","IgE","constant","region","gene","segments","in","the","immunoglobulin","heavy","chain","locus",",","that","is","dependent","on","the","activity","of","interleukin","4","(","IL-4",")"),4144272). assertion_content_comment('oboGo_Interleukin4_Interleukin_4ReceptorComplex',s("A","protein","complex","that","is","formed","by","the","association","of","a","heterodimeric","interleukin-4","receptor","complex","with","an","interleukin-4","molecule","."),4175414). assertion_content_comment('oboGo_Interleukin_4_MediatedSignalingPathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","interleukin-4","binding","to","a","cell","surface","receptor","."),4381143). assertion_content_comment('oboGo_Interleukin_4Production',s("The","appearance","of","interleukin-4","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067790). assertion_content_comment('oboGo_Interleukin_4ReceptorActivity',s("Combining","with","interleukin-4","to","initiate","a","change","in","cell","activity","."),4198627). assertion_content_comment('oboGo_Interleukin_4ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-4","receptor","."),4214505). assertion_content_comment('oboGo_Interleukin_4ReceptorComplex',s("A","protein","complex","that","binds","interleukin-4","(","IL-4",")","and","consists","of","an","alpha","chain","that","binds","IL-4","with","high","affinity","and","a","gamma","common","chain","that","also","forms","part","of","the","interleukin-2","receptor","."),4040553). assertion_content_comment('oboGo_Interleukin_4Secretion',s("The","regulated","release","of","interleukin-4","from","a","cell","or","group","of","cells","."),4126747). assertion_content_comment('oboGo_Interleukin_5Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-5","."),4198601). assertion_content_comment('oboGo_Interleukin_5BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-5","."),4079568). assertion_content_comment('oboGo_Interleukin_5Production',s("The","appearance","of","interleukin-5","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067605). assertion_content_comment('oboGo_Interleukin_5ReceptorActivity',s("Combining","with","interleukin-5","to","initiate","a","change","in","cell","activity","."),4198604). assertion_content_comment('oboGo_Interleukin_5ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-5","receptor","."),4214493). assertion_content_comment('oboGo_Interleukin_5ReceptorComplex',s("A","protein","complex","that","binds","interleukin-3",";","comprises","an","alpha","and","a","beta","subunit",".","The","alpha","chain","is","specific","to","the","interleukin-5","receptor",",","whereas","the","beta","chain","is","shared","with","the","receptors","for","granulocyte-macrophage","colony-stimulating","factor","and","interleukin-3","."),4008315). assertion_content_comment('oboGo_Interleukin_5Secretion',s("The","regulated","release","of","interleukin-5","from","a","cell","or","group","of","cells","."),4126736). assertion_content_comment('oboGo_Interleukin_6Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-6","."),4198647). assertion_content_comment('oboGo_Interleukin_6BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-6","."),4079552). assertion_content_comment('oboGo_Interleukin_6_MediatedSignalingPathway',s("A","series","of","molecular","events","generated","as","a","consequence","of","interleukin-6","binding","to","a","cell","surface","receptor","."),4132891). assertion_content_comment('oboGo_Interleukin_6Production',s("The","appearance","of","interleukin-6","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067568). assertion_content_comment('oboGo_Interleukin_6ReceptorActivity',s("Combining","with","interleukin-6","to","initiate","a","change","in","cell","activity","."),4198650). assertion_content_comment('oboGo_Interleukin_6ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-6","receptor","."),4214529). assertion_content_comment('oboGo_Interleukin_6ReceptorComplex',s("A","hexameric","protein","complex","consisting","of","two","molecules","each","of","interleukin-6",",","interleukin-6","receptor","alpha","chain",",","and","gp-130","."),4008210). assertion_content_comment('oboGo_Interleukin_6Secretion',s("The","regulated","release","of","interleukin-6","from","a","cell","or","group","of","cells","."),4126668). assertion_content_comment('oboGo_Interleukin_7Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-7","."),4198713). assertion_content_comment('oboGo_Interleukin_7BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-7","."),4079536). assertion_content_comment('oboGo_Interleukin_7Production',s("The","appearance","of","interleukin-7","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067679). assertion_content_comment('oboGo_Interleukin_7ReceptorActivity',s("Combining","with","interleukin-7","to","initiate","a","change","in","cell","activity","."),4198716). assertion_content_comment('oboGo_Interleukin_7ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-7","receptor","."),4214517). assertion_content_comment('oboGo_Interleukin_7Secretion',s("The","regulated","release","of","interleukin-7","from","a","cell","or","group","of","cells","."),4126657). assertion_content_comment('oboGo_Interleukin_8Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-8","."),4198690). assertion_content_comment('oboGo_Interleukin_8BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-8","."),4079520). assertion_content_comment('oboGo_Interleukin_8Production',s("The","appearance","of","interleukin-8","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4067642). assertion_content_comment('oboGo_Interleukin_8ReceptorActivity',s("Combining","with","interleukin-8","to","initiate","a","change","in","cell","activity","."),4198693). assertion_content_comment('oboGo_Interleukin_8ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-8","receptor","."),4217475). assertion_content_comment('oboGo_Interleukin_8Secretion',s("The","regulated","release","of","interleukin-8","from","a","cell","or","group","of","cells","."),4126701). assertion_content_comment('oboGo_Interleukin_9Binding',s("Interacting","selectively","and","non-covalently","with","interleukin-9","."),4198736). assertion_content_comment('oboGo_Interleukin_9BiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","interleukin-9","."),4079504). assertion_content_comment('oboGo_Interleukin_9Production',s("The","appearance","of","interleukin-9","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4068405). assertion_content_comment('oboGo_Interleukin_9ReceptorActivity',s("Combining","with","interleukin-9","to","initiate","a","change","in","cell","activity","."),4198739). assertion_content_comment('oboGo_Interleukin_9ReceptorBinding',s("Interacting","selectively","and","non-covalently","with","the","interleukin-9","receptor","."),4214436). assertion_content_comment('oboGo_Interleukin_9ReceptorComplex',s("A","protein","complex","that","binds","interleukin-9",";","comprises","an","alpha","and","a","beta","subunit",".","The","alpha","chain","is","specific","to","the","interleukin-9","receptor",",","whereas","the","beta","chain","is","shared","with","the","receptors","for","several","other","interleukins","."),4008222). assertion_content_comment('oboGo_Interleukin_9Secretion',s("The","regulated","release","of","interleukin-9","from","a","cell","or","group","of","cells","."),4126679). assertion_content_comment('oboGo_InterMaleaggressivebehavior',s("Aggressive","behavior","based","on","competition","between","males","of","the","same","species","over","access","to","resources","such","as","females",",","dominance",",","status",",","etc",".","and","characterized","by","noise",",","threats",",","and","is","often","less","injurious","."),4375598). assertion_content_comment('oboGo_IntermediateConductanceCalciumActivatedpotassiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","potassium","by","a","channel","with","a","unit","conductance","of","20","to","85","picoSiemens","that","opens","in","response","to","stimulus","by","internal","calcium","ions",".","Intermediate","conductance","calcium-activated","potassium","channels","are","more","sensitive","to","calcium","than","are","large","conductance","calcium-activated","potassium","channels",".","Transport","by","a","channel","involves","catalysis","of","facilitated","diffusion","of","a","solute","(","by","an","energy-independent","process",")","involving","passage","through","a","transmembrane","aqueous","pore","or","channel",",","without","evidence","for","a","carrier-mediated","mechanism","."),4333385). assertion_content_comment('oboGo_IntermediateDensitylipoproteinparticlebinding',s("Interacting","selectively","and","non-covalently","with","a","intermediate-density","lipoprotein","particle",",","a","triglyceride-rich","lipoprotein","particle","that","typically","contains","APOB100",",","APOE","and","APOCs","and","has","a","density","of","1.006-1.019","g/ml","and","a","diameter","of","between","25-30","nm","."),4171112). assertion_content_comment('oboGo_IntermediateDensitylipoproteinparticleclearance',s("The","process","in","which","a","intermediate-density","lipoprotein","particle","is","removed","from","the","blood","via","receptor-mediated","endocytosis","and","its","constituent","parts","degraded","."),4170843). assertion_content_comment('oboGo_IntermediateDensitylipoproteinparticleremodeling',s("The","acquisition",",","loss","or","modification","of","a","protein","or","lipid","within","an","intermediate-density","lipoprotein","particle","."),4355726). assertion_content_comment('oboGo_IntermediateDensitylipoproteinparticle',s("A","triglyceride-rich","lipoprotein","particle","that","typically","contains","APOB100",",","APOE","and","APOCs","and","has","a","density","of","1.006-1.019","g/ml","and","a","diameter","of","between","25-30","nm",".","IDL","particles","are","found","in","blood","and","are","formed","by","the","delipidation","of","very-low-density","lipoprotein","particles","(","VLDL",")","IDL","particles","are","removed","from","blood","by","the","liver",",","following","binding","to","the","APOE","receptor",",","or","are","converted","to","low-density","lipoprotein","(","LDL",")"),4355795). assertion_content_comment('oboGo_IntermediateFilamentBasedprocess',s("Any","cellular","process","that","depends","upon","or","alters","the","intermediate","filament","cytoskeleton",",","that","part","of","the","cytoskeleton","comprising","intermediate","filaments","and","their","associated","proteins","."),4051356). assertion_content_comment('oboGo_InternalPeptidylLysineacetylation',s("The","addition","of","an","acetyl","group","to","a","non-terminal","lysine","residue","in","a","protein","."),4072860). assertion_content_comment('oboGo_InterneuronSortingInvolvedInSubstrateIndependentcerebralcortextangentialmigration',s("The","establishment","and","response","to","guidance","cues","that","distribute","interneurons","to","different","cerebral","cortex","structures","."),4050928). assertion_content_comment('oboGo_InterneuronSubstratuminteractioninvolvedininterneuronmigrationfromthesubpalliumtothecortex',s("The","process","in","which","migrating","interneurons","interact","with","an","external","substratum","as","a","component","of","migration","from","the","subpallium","to","the","cortex","."),4051062). assertion_content_comment('oboGo_IntestinalDGlucoseabsorption',s("Uptake","of","D-glucose","into","the","blood","by","absorption","from","the","small","intestine","."),4384211). assertion_content_comment('oboGo_IntracellularLigandGatedcalciumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","channel","that","opens","when","a","specific","intracellular","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158434). assertion_content_comment('oboGo_IntracellularLigandGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","a","specific","intracellular","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158397). assertion_content_comment('oboGo_IntracellularMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","bounded","by","a","single","or","double","lipid","bilayer","membrane","and","occurring","within","the","cell",".","Includes","the","nucleus",",","mitochondria",",","plastids",",","vacuoles",",","and","vesicles",".","Excludes","the","plasma","membrane","."),3971919). assertion_content_comment('oboGo_IntracellularNonMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","not","bounded","by","a","lipid","bilayer","membrane","and","occurring","within","the","cell",".","Includes","ribosomes",",","the","cytoskeleton","and","chromosomes","."),3971807). assertion_content_comment('oboGo_IntraGolgivesicleMediatedtransport',s("The","directed","movement","of","substances","within","the","Golgi",",","mediated","by","small","transport","vesicles",".","These","either","fuse","with","the","cis-Golgi","or","with","each","other","to","form","the","membrane","stacks","known","as","the","cis-Golgi","reticulum","(","network",")"),4229003). assertion_content_comment('oboGo_IntramolecularOxidoreductaseActivityInterconvertingKetoAndenolGroups',s("Catalysis","of","an","oxidation-reduction","(","redox",")","reaction","in","which","the","hydrogen","donor","and","acceptor",",","which","is","a","keto-","or","an","enol-group",",","are","the","same","molecule",",","and","no","oxidized","product","appears","."),4192477). assertion_content_comment('oboGo_IntramolecularOxidoreductaseActivityTransposingSSbonds',s("Catalysis","of","an","oxidation-reduction","(","redox",")","reaction","in","which","the","hydrogen","donor","and","acceptor","are","the","same","molecule",",","one","or","more","sulfur-sulfur","bonds","in","the","molecule","are","rearranged",",","and","no","oxidized","product","appears","."),4192489). assertion_content_comment('oboGo_IntramolecularProlineRichligandbinding',s("Interacting","selectively","and","non-covalently","with","a","proline-rich","region","within","the","same","polypeptide","."),4337284). assertion_content_comment('oboGo_IntraSdnadamagecheckpoint',s("A","cell","cycle","checkpoint","that","slows","DNA","synthesis","in","response","to","DNA","damage","by","the","prevention","of","new","origin","firing","and","the","stabilization","of","slow","replication","fork","progession","."),4128237). assertion_content_comment('oboGo_IntrinsicToFungalTypevacuolarmembrane',s("Located","in","the","fungal-type","vacuolar","membrane","such","that","some","covalently","attached","portion","of","the","gene","product",",","for","example","part","of","a","peptide","sequence","or","some","other","covalently","attached","group","such","as","a","GPI","anchor",",","spans","or","is","embedded","in","one","or","both","leaflets","of","the","membrane","."),4130232). assertion_content_comment('oboGo_IntronicTranscriptionRegulatoryRegionSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","an","intronic","DNA","sequence","that","regulates","the","transcription","of","the","transcript","it","is","contained","within","."),4357788). assertion_content_comment('oboGo_InulinFructotransferaseDFAIFormingactivity',s("Catalysis","of","the","production","of","alpha-D-fructofuranose","beta-D-fructofuranose","1",",","2","'",":","2",",","1","'","-dianhydride","(","DFA","I",")","by","successively","eliminating","the","diminishing","(","2-","&","gt",";","1",")","-beta-D-fructan","(","inulin",")","chain","from","the","terminal","D-fructosyl-D-fructosyl","disaccharide","."),4345164). assertion_content_comment('oboGo_InulinFructotransferaseDFAIiiFormingactivity',s("Catalysis","of","the","production","of","alpha-D-fructofuranose","beta-D-fructofuranose","1",",","2","'",":","2",",","3","'","-dianhydride","(","DFA","III",")","by","successively","eliminating","the","diminishing","(","2-","&","gt",";","1",")","-beta-D-fructan","(","inulin",")","chain","from","the","terminal","D-fructosyl-D-fructosyl","disaccharide","."),4345178). assertion_content_comment('oboGo_InvasiveGrowth_7',s("OBSOLETE",".","Growth","of","a","pathogenic","organism","that","results","in","penetration","into","cells","or","tissues","of","the","host","organism",".","This","often","(","but","not","necessarily",")","includes","a","filamentous","growth","form",",","and","also","can","include","secretion","of","proteases","and","lipases","to","break","down","host","tissue","."),4360409). assertion_content_comment('oboGo_IodophenolOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","2-iodophenol","+","S-adenosyl-L-methionine","=","1-iodo-2-methoxybenzene","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308884). assertion_content_comment('oboGo_IotaCarrageenaseactivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-linkages","between","D-galactose","4-sulfate","and","3",",","6-anhydro-D-galactose-2-sulfate","in","iota-carrageenans","."),4344479). assertion_content_comment('oboGo_IP_10Production',s("The","appearance","of","IP-10","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4129137). assertion_content_comment('oboGo_IronAndMolybdenumIncorporationIntoIronMolybdenumSulfurclustervialCysteinylhomocitrylmolybdenumHeptaironNonasulfide',s("The","incorporation","of","iron","and","molybdenum","into","a","Mo-7Fe-8S","iron-molybdenum-sulfur","cluster","via","L-cysteinyl","homocitryl","molybdenum-heptairon-nonasulfide",",","found","in","nitrogenase","."),4280797). assertion_content_comment('oboGo_IronChelateTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","iron","chelate","(","out",")","=","ADP","+","phosphate","+","iron","chelate","(","in",")","Fe-enterobactin",",","Fe-dicitrate",",","Fe-hydroxamate","and","other","siderophores","are","imported","."),4289412). assertion_content_comment('oboGo_IronCytochromeCreductaseactivity',s("Catalysis","of","the","reaction",":","ferrocytochrome","c","+","Fe3","+","=","ferricytochrome","c","+","Fe2","+"),4373588). assertion_content_comment('oboGo_IronIncorporationIntoHydrogenaseDiironSubclusterViaLCysteineligation',s("The","incorporation","of","iron","into","an","L-cysteinyl","diiron","subcluster",",","found","in","Fe-hydrogenase","."),4357240). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviabisLCysteinylLN3HistidinoLSerinyltetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","bis-L-cysteinyl-L-N3","'","-histidino-L-serinyl","tetrairon","tetrasulfide","."),4279279). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviahexakisLCysteinylhexaironhexasulfide',s("OBSOLETE",".","The","incorporation","of","iron","into","a","6Fe-6S","cluster","by","hexakis-L-cysteinyl","hexairon","hexasulfide","."),4279315). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviahexakisLCysteinyllSerinyloctaironheptasulfide',s("The","incorporation","of","iron","into","a","8Fe-7S","iron-sulfur","cluster","via","hexakis-L-cysteinyl","L-serinyl","octairon","heptasulfide",",","found","in","nitrogenase","."),4281639). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviahexakisLCysteinyltriirontrisulfide',s("OBSOLETE",".","The","incorporation","of","iron","into","a","3Fe-3S","iron-sulfur","cluster","via","hexakis-L-cysteinyl","triiron","trisulfide",".","The","three-iron","three-sulfur","cluster","probably","does","not","exist","except","as","an","intermediate","form","."),4281115). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviapentakisLCysteinyllHistidinonickeltetraironpentasulfide',s("The","incorporation","of","iron","into","a","nickel-iron-sulfur","cluster","via","pentakis-L-cysteinyl","L-histidino","nickel","tetrairon","pentasulfide",",","found","in","carbon","monoxide","dehydrogenase","."),4245027). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatetrakisLCysteinyldiirondisulfide',s("The","incorporation","of","iron","into","a","2Fe-2S","iron-sulfur","cluster","via","tetrakis-L-cysteinyl","diiron","disulfide","."),4281127). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatetrakisLCysteinyltetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tetrakis-L-cysteinyl","tetrairon","tetrasulfide","."),4281150). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatetrakisLCysteinyltriirontetrasulfide',s("The","incorporation","of","iron","into","a","3Fe-4S","iron-sulfur","cluster","via","tetrakis-L-cysteinyl","triiron","tetrasulfide","."),4299449). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinyllArginyldiirondisulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl","L-arginyl","diiron","disulfide","."),4274522). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLAspartatodiirondisulfide',s("The","incorporation","of","iron","into","a","2Fe-2S","iron-sulfur","cluster","via","tris-L-cysteinyl-L-aspartato","diiron","disulfide","."),4358417). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLAspartatotetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl-L-aspartato","tetrairon","tetrasulfide","."),4279252). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinyllCysteinepersulfidobisLGlutamatolHistidinonickeltriirondisulfidetrioxide',s("The","incorporation","of","iron","into","a","3Fe-2S","cluster","via","tris-L-cysteinyl","L-cysteine","persulfido","bis-L-glutamato","L-histidino","nickel","triiron","disulfide","trioxide","."),4281511). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLCysteinepersulfidoBisLGlutamatoLHistidinotetrairon',s("The","incorporation","of","iron","into","an","iron-sulfur","cluster","by","tris-L-cysteinyl-L-cysteine","persulfido-bis-L-glutamato-L-histidino","tetrairon","."),4279342). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinyllCysteinepersulfidolGlutamatolHistidinolSerinylnickeltriirondisulfidetrioxide',s("The","incorporation","of","iron","into","a","3Fe-2S","cluster","by","tris-L-cysteinyl","L-cysteine","persulfido","L-glutamato","L-histidino","L-serinyl","nickel","triiron","disulfide","trioxide","."),4281471). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLN1Histidinotetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl-L-N1","'","-histidino","tetrairon","tetrasulfide","."),4279328). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLN3Histidinotetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl-L-N3","'","-histidino","tetrairon","tetrasulfide","."),4279265). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylLSerinyltetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl-L-serinyl","tetrairon","tetrasulfide","."),4279292). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinylsAdenosylmethionNoDiyltetrairontetrasulfide',s("The","incorporation","of","iron","into","a","4Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl","S-adenosylmethion-N",",","O-diyl","tetrairon","tetrasulfide","."),4274554). assertion_content_comment('oboGo_IronIncorporationIntoIronSulfurclusterviatrisLCysteinyltriirontetrasulfide',s("The","incorporation","of","iron","into","a","3Fe-4S","iron-sulfur","cluster","via","tris-L-cysteinyl","triiron","tetrasulfide","."),4281102). assertion_content_comment('oboGo_IronIncorporationIntoMetalloSulfurcluster',s("The","incorporation","of","iron","into","a","metallo-sulfur","cluster","."),4245024). assertion_content_comment('oboGo_IronIncorporationIntoProteinViaTetrakisLCysteinyliron',s("The","incorporation","of","iron","into","a","protein","via","tetrakis-L-cysteinyl","iron","(","there","is","no","exogenous","sulfur",",","so","this","modification","by","itself","does","not","produce","an","iron-sulfur","protein",")"),4281139). assertion_content_comment('oboGo_IronIncorporationIntoTheRieskeIronSulfurclusterviabisLCysteinylbisLHistidinodiirondisulfide',s("The","incorporation","of","iron","into","a","Rieske","4Fe-4S","iron-sulfur","cluster","via","bis-L-cysteinyl","bis-L-histidino","diiron","disulfide","."),4280937). assertion_content_comment('oboGo_IronIronnitrogenaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","8","reduced","ferredoxin","+","8","H","+","+","N2","+","16","ATP","=","8","oxidized","ferredoxin","+","2","NH3","+","16","ADP","+","16","phosphate","."),4301401). assertion_content_comment('oboGo_IronIronnitrogenasecomplex',s("An","enzyme","complex","containing","an","iron-iron","cluster","found","in","species","such","as","the","photosynthetic","bacterium","Rhodobacter","capsulatus",".","It","is","composed","of","two","main","subunits",",","dinitrogenase","and","nitrogenase","reductase",".","Dinitrogenase",",","the","iron-iron","containing","subunit",",","has","an","alpha1-beta2","or","alpha2-beta2","structure",",","and","the","nitrogenase","reductase","subunit","is","a","homodimer",".","Functions","in","the","catalysis","of","the","formation","of","oxidized","ferredoxin","and","ammonia","from","reduced","ferredoxin","and","nitrogen","."),4301398). assertion_content_comment('oboGo_IronNicotianaminetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","the","iron","chelate","iron-nicotianamine","(","Fe-NA",")","from","one","side","of","a","membrane","to","the","other","."),4183850). assertion_content_comment('oboGo_IronResponsiveelementbinding',s("Interacting","selectively","and","non-covalently","with","the","iron-responsive","element",",","a","regulatory","sequence","found","in","the","5","'","-","and","3","'","-untranslated","regions","of","mRNAs","encoding","many","iron-binding","proteins","."),4309533). assertion_content_comment('oboGo_IronSulfurclusterassembly',s("The","incorporation","of","iron","and","exogenous","sulfur","into","a","metallo-sulfur","cluster","."),4245019). assertion_content_comment('oboGo_IronSulfurclusterbinding',s("Interacting","selectively","and","non-covalently","with","an","iron-sulfur","cluster",",","a","combination","of","iron","and","sulfur","atoms","."),4283728). assertion_content_comment('oboGo_IronSulfurelectrontransfercarrier',s("OBSOLETE",".","An","iron-sulfur","protein","that","serves","as","an","electron","acceptor","and","electron","donor","in","an","electron","transport","system","."),4246818). assertion_content_comment('oboGo_ISG15Proteinconjugation',s("The","covalent","addition","to","a","protein","of","ISG15",",","a","ubiquitin-like","protein","."),4330656). assertion_content_comment('oboGo_ISG15Specificproteaseactivity',s("Catalysis","of","the","hydrolysis","of","ISG15",",","a","small","ubiquitin-related","modifier",",","from","previously","modified","substrates","."),4245397). assertion_content_comment('oboGo_ISmadbinding',s("Interacting","selectively","and","non-covalently","with","an","inhibitory","SMAD","signaling","protein","."),4175521). assertion_content_comment('oboGo_IsobutylamineNHydroxylaseactivity',s("Catalysis","of","the","reaction",":","isobutylamine","+","NADPH","+","O2","=","isobutylhydroxylamine","+","NADP","+","+","H2O","."),4349794). assertion_content_comment('oboGo_IsobutyraldoximeOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","2-methylpropanal","oxime","+","S-adenosyl-L-methionine","=","2-methylpropanal","O-methyloxime","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308444). assertion_content_comment('oboGo_IsobutyrylCoamutaseactivity',s("Catalysis","of","the","reaction",":","isobutyryl-CoA","=","butanoyl-CoA","."),4373624). assertion_content_comment('oboGo_IsocitrateHomoisocitratedehydrogenaseactivity',s("Catalysis","of","the","reactions",":","isocitrate","+","NAD","+","=","2-oxoglutarate","+","CO2","+","NADH",",","and","(","1R",",","2S",")","-1-hydroxybutane-1",",","2",",","4-tricarboxylate","+","NAD","+","=","2-oxoadipate","+","CO2","+","NADH","+","H","+"),4341879). assertion_content_comment('oboGo_IsocitrateHydroLyasecisAconitateFormingactivity',s("Catalysis","of","the","reaction",":","cis-aconitate","+","H2O","=","isocitrate","."),4191603). assertion_content_comment('oboGo_IsocitrateODihydroxycinnamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","caffeoyl-CoA","+","isocitrate","=","2-caffeoylisocitrate","+","CoA","."),4365182). assertion_content_comment('oboGo_IsoEugenolOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","isoeugenol","=","S-adenosyl-L-homocysteine","+","isomethyleugenol","."),4277816). assertion_content_comment('oboGo_Isoflavone2Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","an","isoflavone","+","NADPH","+","H","+","+","O2","=","a","2","'","-hydroxyisoflavone","+","NADP","+","+","H2O","."),4342218). assertion_content_comment('oboGo_Isoflavone3Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","formononetin","+","NADPH","+","O2","=","calycosin","+","NADP","+","+","H2O","."),4384689). assertion_content_comment('oboGo_Isoflavone4OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","isoflavone","=","S-adenosyl-L-homocysteine","+","4","'","-O-methylisoflavone","."),4308733). assertion_content_comment('oboGo_Isoflavone_7_O_Beta_Glucoside6_O_MalonyltransferaseActivity',s("Catalysis","of","the","reaction",":","biochanin-A","+","malonyl-CoA","=","6","'","-malonyl-biochanin","A","+","CoA","."),4365213). assertion_content_comment('oboGo_Isoflavone7OGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-glucose","+","isoflavone","=","UDP","+","isoflavone","7-O-beta-D-glucoside","."),4270391). assertion_content_comment('oboGo_Isoflavone7OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","a","7-hydroxyisoflavone","=","S-adenosyl-L-homocysteine","+","a","7-methoxyisoflavone","."),4342877). assertion_content_comment('oboGo_IsohexenylglutaconylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","3-hydroxy-3-","(","4-methylpent-3-en-1-yl",")","glutaryl-CoA","=","3-","(","4-methylpent-3-en-1-yl",")","pent-2-enedioyl-CoA","+","H","(","2",")","O","."),4270405). assertion_content_comment('oboGo_IsoleucineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","L-isoleucine","+","ATP","+","tRNA","(","Ile",")","=","L-isoleucyl-tRNA","(","Ile",")","+","AMP","+","diphosphate","+","2","H","(","+",")"),4199850). assertion_content_comment('oboGo_IsoleucylTrnaaminoacylation',s("The","process","of","coupling","isoleucine","to","isoleucyl-tRNA",",","catalyzed","by","isoleucyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179739). assertion_content_comment('oboGo_Isoliquiritigenin2OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","isoliquiritigenin","=","2","'","-O-methylisoliquiritigenin","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4342888). assertion_content_comment('oboGo_Isoorientin3OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","isoorientin","=","S-adenosyl-L-homocysteine","+","H","(","+",")","+","isoscoparin","."),4308619). assertion_content_comment('oboGo_IsopenicillinNepimeraseactivity',s("Catalysis","of","the","reaction",":","isopenicillin","N","=","penicillin","N","."),4299516). assertion_content_comment('oboGo_IsopenicillinNnAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","phenylacetyl-CoA","+","isopenicillin","N","+","H2O","=","CoA","+","penicillin","G","+","L-2-aminohexanedioate","."),4277706). assertion_content_comment('oboGo_IsopenicillinNsynthaseactivity',s("Catalysis","of","the","reaction",":","N-","[","(","5S",")","-5-amino-5-carboxypentanoyl","]","-L-cysteinyl-D-valine","+","O","(","2",")","=","2","H","(","2",")","O","+","isopenicillin","N","."),4303900). assertion_content_comment('oboGo_IsopentenylDiphosphateBiosyntheticProcessMevalonateIndependentpathwayinvolvedinterpenoidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","isopentenyl","diphosphate","by","the","mevalonate-independent","pathway","that","contributes","to","terpenoid","biosynthesis",".","Isopentenyl","diphosphate","(","IPP",")","is","the","fundamental","unit","in","isoprenoid","biosynthesis","and","is","biosynthesized","from","pyruvate","and","glyceraldehyde","3-phosphate","via","intermediates",",","including","1-deoxy-D-xylulose","5-phosphate","."),4119021). assertion_content_comment('oboGo_IsopentenylDiphosphateBiosyntheticProcessMevalonateIndependentpathway',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","isopentenyl","diphosphate","by","the","mevalonate-independent","pathway",".","Isopentenyl","diphosphate","(","IPP",")","is","the","fundamental","unit","in","isoprenoid","biosynthesis","and","is","biosynthesized","from","pyruvate","and","glyceraldehyde","3-phosphate","via","intermediates",",","including","1-deoxy-D-xylulose","5-phosphate","."),4030712). assertion_content_comment('oboGo_IsopentenylDiphosphatedeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","isopentenyl","diphosphate","=","dimethylallyl","diphosphate","."),4206824). assertion_content_comment('oboGo_IsopeptideCrossLinking',s("The","formation","of","a","covalent","cross-link","between","or","within","peptide","chains",",","where","either","the","amino","group","or","the","carboxyl","group",",","or","both",",","are","not","attached","to","the","alpha","carbon","."),4040473). assertion_content_comment('oboGo_IsopeptideCrossLinkingvian6GlycylLLysine',s("The","formation","of","an","isopeptide","cross-link","between","peptidyl-lysine","and","peptidyl-glycine","to","produce","N6-glycyl-L-lysine",".","This","is","distinct","from","the","formation","of","the","thiolester","intermediate",",","which","occurs","during","ubiquitination","."),4040476). assertion_content_comment('oboGo_IsopeptideCrossLinkingvian6LIsoglutamylLLysine',s("The","formation","of","an","isopeptide","cross-link","between","peptidyl-lysine","and","peptidyl-glutamine","to","produce","N6-","(","L-isoglutamyl",")","-L-lysine","."),4284724). assertion_content_comment('oboGo_IsopeptideCrossLinkingvianLIsoaspartylGlycine',s("The","formation","of","an","isopeptide","cross-link","between","peptidyl-asparagine","and","peptidyl-glycine","to","produce","N-","(","L-isoaspartyl",")","-glycine","."),4280698). assertion_content_comment('oboGo_IsopeptideCrossLinkingvianLIsoaspartylLCysteine',s("The","formation","of","an","isopeptide","cross-link","between","peptidyl-asparagine","and","peptidyl-cysteine","to","produce","N-","(","L-isoaspartyl",")","-L-cysteine","."),4280710). assertion_content_comment('oboGo_IsopeptideCrossLinkingvianLIsoglutamylGlycine',s("The","formation","of","an","isopeptide","cross-link","between","peptidyl-glutamate","and","peptidyl-glycine","to","produce","N-","(","L-isoglutamyl",")","-glycine",",","as","found","in","the","antibiotic","microcin","J25","."),4273011). assertion_content_comment('oboGo_IsopiperitenoneDeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","isopiperitenone","=","piperitenone","."),4270442). assertion_content_comment('oboGo_Isopiperitenonereductaseactivity',s("Catalysis","of","the","reaction",":","(","6R",")","-isoperitenone","+","H","(","+",")","+","NADPH","=","(","2R",",","5R",")","-isopulegone","+","NADP","(","+",")"),4186373). assertion_content_comment('oboGo_Isoquinoline1Oxidoreductaseactivity',s("Catalysis","of","the","reaction",":","A","+","H","(","2",")","O","+","isoquinoline","=","AH","(","2",")","+","isoquinolin-1","(","2H",")","-one","."),4365734). assertion_content_comment('oboGo_IsovalerylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","3-methylbutanoyl-CoA","+","ETF","=","3-methylbut-2-enoyl-CoA","+","reduced","ETF","."),4254283). assertion_content_comment('oboGo_IsovitexinBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","isovitexin","+","UDP-D-glucose","=","H","(","+",")","+","isovitexin","2","'","'","-O-beta-D-glucoside","+","UDP","."),4270378). assertion_content_comment('oboGo_ItaconylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","citramalyl-CoA","=","itaconyl-CoA","+","H2O","."),4270366). assertion_content_comment('oboGo_JAKInducedstatproteindimerization',s("The","formation","of","a","dimer","of","two","STAT","proteins","(","Signal","Transducers","and","Activators","of","Transcription",")","following","their","activation","by","members","of","the","janus","activated","kinase","(","JAK",")","family","of","tyrosine","kinases","."),4016701). assertion_content_comment('oboGo_JAKStatcascadeinvolvedingrowthhormonesignalingpathway',s("The","process","in","which","STAT","proteins","(","Signal","Transducers","and","Activators","of","Transcription",")","are","activated","by","members","of","the","JAK","(","janus","activated","kinase",")","family","of","tyrosine","kinases",",","following","the","binding","of","physiological","ligands","to","the","growth","hormone","receptor",".","Once","activated",",","STATs","dimerize","and","translocate","to","the","nucleus","and","modulate","the","expression","of","target","genes","."),4117395). assertion_content_comment('oboGo_JAKStatcascade',s("Any","process","in","which","STAT","proteins","(","Signal","Transducers","and","Activators","of","Transcription",")","are","activated","by","members","of","the","JAK","(","janus","activated","kinase",")","family","of","tyrosine","kinases",",","following","the","binding","of","cytokines","to","their","cognate","receptor",".","Once","activated",",","STATs","dimerize","and","translocate","to","the","nucleus","and","modulate","the","expression","of","target","genes","."),4016650). assertion_content_comment('oboGo_JasmonateAminosynthetaseactivity',s("Catalysis","of","the","reaction",":","jasmonate","+","an","amino","acid","=","an","amide-linked","jasmonyl-amino","acid","conjugate",".","The","substrates","of","this","reaction","include","non-standard","amino","acids",",","such","as","ACC","(","1-aminocyclopropane-1-carboxylate",")"),4181544). assertion_content_comment('oboGo_JasmonateOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","jasmonate","=","S-adenosyl-L-homocysteine","+","methyljasmonate","."),4309066). assertion_content_comment('oboGo_JasmonicAcidAndEthyleneDependentsystemicresistanceethylenemediatedsignalingpathway',s("The","series","of","molecular","signals","mediated","by","ethylene","(","ethene",")","involved","in","jasmonic","acid/ethylene","dependent","systemic","resistance","."),4022225). assertion_content_comment('oboGo_JasmonicAcidAndEthyleneDependentsystemicresistancejasmonicacidmediatedsignalingpathway',s("The","series","of","molecular","signals","mediated","by","jasmonic","acid","involved","in","jasmonic","acid/ethylene","(","ethene",")","dependent","systemic","resistance","."),4262619). assertion_content_comment('oboGo_JasmonicAcidAndEthyleneDependentsystemicresistance',s("The","jasmonic","acid","and","ethylene","(","ethene",")","dependent","process","that","confers","broad","spectrum","systemic","resistance","to","disease","in","response","to","wounding","or","a","pathogen","."),4022213). assertion_content_comment('oboGo_Juglone3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","5-hydroxy-1",",","4-naphthoquinone","+","AH","(","2",")","+","O","(","2",")","=","3",",","5-dihydroxy-1",",","4-naphthoquinone","+","A","+","H","(","2",")","O","+","H","(","+",")"),4270353). assertion_content_comment('oboGo_JuvenileHormoneBinding_3',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4229377). assertion_content_comment('oboGo_JuvenileHormoneesteraseactivity',s("Catalysis","of","the","reaction",":","methyl","(","2E",",","6E",")","-","(","10R",",","11S",")","-10",",","11-epoxy-3",",","7",",","11-trimethyltrideca-2",",","6-dienoate","+","H2O","=","(","2E",",","6E",")","-","(","10R",",","11S",")","-10",",","11-epoxy-3",",","7",",","11-trimethyltrideca-2",",","6-dienoate","+","methanol",".","A","carboxylesterase","that","hydrolyzes","the","ester","linkage","of","juvenile","hormone","."),4206841). assertion_content_comment('oboGo_K11Linkedpolyubiquitinbinding',s("Interacting","selectively","and","non-covalently","and","non-covalently","with","a","polymer","of","ubiquitin","formed","by","linkages","between","lysine","residues","at","position","11","of","the","ubiquitin","monomers","."),4169416). assertion_content_comment('oboGo_K63Linkedpolyubiquitinbinding',s("Interacting","selectively","and","non-covalently","and","non-covalently","with","a","polymer","of","ubiquitin","formed","by","linkages","between","lysine","residues","at","position","63","of","the","ubiquitin","monomers","."),4174411). assertion_content_comment('oboGo_K6Linkedpolyubiquitinbinding',s("Interacting","selectively","and","non-covalently","and","non-covalently","with","a","polymer","of","ubiquitin","formed","by","linkages","between","lysine","residues","at","position","6","of","the","ubiquitin","monomers","."),4169407). assertion_content_comment('oboGo_Kaempferol3OGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","kaempferol","=","UDP","+","kaempferol","3-O-beta-D-galactoside","."),4343377). assertion_content_comment('oboGo_Kaempferol4OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","kaempferol","=","S-adenosyl-L-homocysteine","+","H","(","+",")","+","kaempferide","."),4342928). assertion_content_comment('oboGo_KaempferolOGlucosidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","leading","to","the","formation","of","O-glucosylated","derivatives","of","kaempferol","."),4338577). assertion_content_comment('oboGo_KaempferolOGlucosidemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","O-glucosylated","derivatives","of","kaempferol","."),4338574). assertion_content_comment('oboGo_KappaCarrageenaseactivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-linkages","between","D-galactose","4-sulfate","and","3",",","6-anhydro-D-galactose","in","kappa-carrageenans","."),4344254). assertion_content_comment('oboGo_KappaOpioidreceptoractivity',s("Combining","with","an","opioid","to","initiate","a","change","in","cell","activity",",","with","the","pharmacological","characteristics","of","kappa-opioid","receptors",",","including","high","affinity","for","dynorphins","."),4198940). assertion_content_comment('oboGo_KappaTypeopioidreceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","kappa-type","opioid","receptor","."),4323981). assertion_content_comment('oboGo_Keratan_SulfateEndo_14_Beta_GalactosidaseActivity',s("Catalysis","of","the","endohydrolysis","of","1",",","4-beta-D-galactosidic","linkages","in","keratan","sulfate","."),4344751). assertion_content_comment('oboGo_Keto_3_Deoxy_D_Manno_OctulosonicAcidBiosyntheticProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","keto-3-deoxy-D-manno-octulosonic","acid",",","an","acidic","sugar","present","in","lipopolysaccharides","of","the","outer","membranes","of","some","Gram-negative","bacteria","."),4046031). assertion_content_comment('oboGo_Keto_3_Deoxy_D_Manno_OctulosonicAcidMetabolicProcess',s("The","chemical","reactions","and","pathways","involving","keto-3-deoxy-D-manno-octulosonic","acid",",","an","acidic","sugar","present","in","lipopolysaccharides","of","the","outer","membranes","of","some","Gram-negative","bacteria","."),4046024). assertion_content_comment('oboGo_KetolAcidreductoisomeraseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-2",",","3-dihydroxy-3-methylbutanoate","+","NADP","+","=","(","S",")","-2-hydroxy-2-methyl-3-oxobutanoate","+","NADPH","+","H","+"),4206981). assertion_content_comment('oboGo_KetotetrosePhosphatealdolaseactivity',s("Catalysis","of","the","reaction",":","L-erythrulose","1-phosphate","=","formaldehyde","+","glycerone","phosphate","."),4270011). assertion_content_comment('oboGo_KinesinAssociatedmelanosomaladaptoractivity',s("The","activity","of","linking","kinesins",",","cytoplasmic","proteins","responsible","for","moving","vesicles","and","organelles","towards","the","distal","end","of","microtubules",",","to","melanosomes","."),4380223). assertion_content_comment('oboGo_KinesinAssociatedmitochondrialadaptoractivity',s("The","activity","of","linking","kinesins",",","cytoplasmic","proteins","responsible","for","moving","vesicles","and","organelles","towards","the","distal","end","of","microtubules",",","to","mitochondria","."),4233907). assertion_content_comment('oboGo_KuDnaligasecomplex',s("A","nonhomologous","end","joining","complex","that","contains","one","or","more","Ku","monomers","and","one","or","more","DNA","ligase","molecules","from","the","LigC","or","LigD","family",",","and","mediates","nonhomologous","end","joining","in","bacteria","."),4175540). assertion_content_comment('oboGo_Kv41Dpp10channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","peptidase-related","protein","DPP10","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.1","."),4165110). assertion_content_comment('oboGo_Kv41Dpp6channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","peptidase-related","protein","DPP6","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.1","."),4165157). assertion_content_comment('oboGo_Kv42Dpp6channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","peptidase-related","protein","DPP6","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.2","."),4165343). assertion_content_comment('oboGo_Kv42Kchip1channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","channel","interacting","protein","KChIP1","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.2","."),4165208). assertion_content_comment('oboGo_Kv42Kchip2channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","channel","interacting","protein","KChIP2","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.2","."),4165182). assertion_content_comment('oboGo_Kv42Kchip3channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","channel","interacting","protein","KChIP3","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.2","."),4165190). assertion_content_comment('oboGo_Kv42Kchip4channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","channel","interacting","protein","KChIP4","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.2","."),4165166). assertion_content_comment('oboGo_Kv42Kv43channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","alpha","subunits","4.2","and","4.3","."),4165149). assertion_content_comment('oboGo_Kv43Dpp10channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","peptidase-related","protein","DPP10","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.3","."),4165361). assertion_content_comment('oboGo_Kv43Dpp6channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","peptidase-related","protein","DPP6","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.3","."),4165352). assertion_content_comment('oboGo_Kv43Kchip1channelcomplex',s("A","voltage-gated","potassium","channel","complex","that","contains","the","Kv","channel","interacting","protein","KChIP1","associated","with","the","channel","via","interaction","with","the","Kv","alpha","subunit","4.3","."),4165174). assertion_content_comment('oboGo_Kynurenate_78_DihydrodiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","7",",","8-dihydro-7",",","8-dihydroxykynurenate","+","NAD","(","+",")","=","7",",","8-dihydroxykynurenate","+","H","(","+",")","+","NADH","."),4365915). assertion_content_comment('oboGo_Kynurenine3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","L-kynurenine","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","3-hydroxy-L-kynurenine","+","H","(","2",")","O","+","NADP","(","+",")"),4205405). assertion_content_comment('oboGo_Kynurenine78Hydroxylaseactivity',s("Catalysis","of","the","reaction",":","kynurenate","+","donor-H2","+","O2","=","7",",","8-dihydro-7",",","8-dihydroxykynurenate","+","acceptor","."),4270037). assertion_content_comment('oboGo_KynurenineGlyoxylatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-kynurenine","+","glyoxylate","=","4-","(","2-aminophenyl",")","-2",",","4-dioxobutanoate","+","glycine","."),4368881). assertion_content_comment('oboGo_KynurenineOxoglutaratetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-kynurenine","+","2-oxoglutarate","=","4-","(","2-aminophenyl",")","-2",",","4-dioxobutanoate","+","L-glutamate","."),4303973). assertion_content_comment('oboGo_L_2_Amino_4_Chloropent_4_EnoateDehydrochlorinaseActivity',s("Catalysis","of","the","reaction",":","L-2-amino-4-chloropent-4-enoate","+","H","(","2",")","O","=","2-oxopent-4-enoate","+","chloride","+","H","(","+",")","+","NH","(","4",")","(","+",")"),4369556). assertion_content_comment('oboGo_L_2_AminoadipateN_AcetyltransferaseActivity',s("Catalysis","of","the","reaction",":","L-2-aminoadipate","+","acetyl-CoA","=","N2-acetyl-L-aminoadipate","+","CoA","."),4325853). assertion_content_comment('oboGo_L_2_HydroxyglutarateOxidaseActivity',s("Catalysis","of","the","reaction",":","L-2-hydroxyglutarate","+","O2","=","2-oxoglutarate","+","hydrogen","peroxide","."),4357383). assertion_content_comment('oboGo_L_3_CyanoalanineSynthaseActivity',s("Catalysis","of","the","reaction",":","L-cysteine","+","HCN","=","sulfide","+","L-3-cyanoalanine","."),4269988). assertion_content_comment('oboGo_Lactate2Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-lactate","+","O","(","2",")","=","acetate","+","CO","(","2",")","+","H","(","2",")","O","."),4270220). assertion_content_comment('oboGo_LactateMalatetranshydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-lactate","+","oxaloacetate","=","malate","+","pyruvate","."),4270250). assertion_content_comment('oboGo_LactoNBiosidaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","beta-D-Gal-","(","1",",","3",")","-beta-D-GlcNAc-","(","1",",","3",")","-beta-D-Gal-","(","1",",","4",")","-D-Glc","=","beta-D-Gal-","(","1",",","4",")","-D-Glc","+","beta-D-Gal-","(","1",",","3",")","-D-GlcNAc","."),4370443). assertion_content_comment('oboGo_LactoseCatabolicProcessUsingGlucoside3Dehydrogenase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","lactose",",","catalyzed","by","the","enzyme","glucoside","3-dehydrogenase","(","EC",":","1.1.99.13",")"),4242229). assertion_content_comment('oboGo_LactoseCatabolicProcessViaTagatose_6_Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","lactose",",","via","the","intermediate","tagatose-6-phosphate","."),4242341). assertion_content_comment('oboGo_LactoseCatabolicProcessViaUDPGalactose',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","lactose",",","via","the","intermediate","UDP-galactose","."),4242252). assertion_content_comment('oboGo_Lactosylceramide13NAcetylBetaDGlucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","cytolipin-H","+","UDP-N-acetyl-D-glucosamine","=","N-acetyl-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","+","UDP","."),4367273). assertion_content_comment('oboGo_Lactosylceramide4AlphaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","beta-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP-galactose","=","alpha-D-galactosyl-","(","1",",","4",")","-beta-D-galactosyl-","(","1",",","4",")","-D-glucosylceramide","+","UDP","."),4269191). assertion_content_comment('oboGo_LactosylceramideAlpha_23_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","cytolipin-H","+","CMP-N-acetylneuraminate","=","alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","+","CMP",".","Alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","is","also","known","as","GM3","."),4367606). assertion_content_comment('oboGo_LactosylceramideAlpha_26_N_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","cytolipin-H","+","CMP-N-acetylneuraminate","=","alpha-N-acetylneuraminyl-2",",","6-beta-galactosyl-1",",","4-beta-D-glucosylceramide","+","CMP","."),4367334). assertion_content_comment('oboGo_LactosylceramideBeta_13_GalactosyltransferaseActivity',s("Catalysis","of","the","reaction",":","D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-glucosyl-R","+","UDP-D-galactose","=","D-galactosyl-","(","1-","&","gt",";","3",")","-beta-D-galactosyl-","(","1-","&","gt",";","4",")","-beta-D-glucosyl-R","+","H","(","+",")","+","UDP","."),4366847). assertion_content_comment('oboGo_LactoylCoadehydrataseactivity',s("Catalysis","of","the","reaction",":","lactoyl-CoA","=","acryloyl-CoA","+","H2O","."),4273606). assertion_content_comment('oboGo_LAlanine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-alanine","=","L-glutamate","+","pyruvate","."),4213244). assertion_content_comment('oboGo_LAlaninebiosyntheticprocessfrompyruvate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","alanine","from","other","compounds",",","including","pyruvate","."),4238791). assertion_content_comment('oboGo_LAlaninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-alanine",",","the","L-enantiomer","of","2-aminopropanoic","acid",",","i.e",".","(","2S",")","-2-aminopropanoic","acid","."),4238771). assertion_content_comment('oboGo_LAlaninebiosyntheticprocessviaornithine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-alanine",",","via","the","intermediate","ornithine","."),4238777). assertion_content_comment('oboGo_LAlaninecatabolicprocessbytransamination',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-alanine","by","transamination","."),4241070). assertion_content_comment('oboGo_LAlaninecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-alanine",",","the","L-enantiomer","of","2-aminopropanoic","acid",",","i.e",".","(","2S",")","-2-aminopropanoic","acid","."),4241043). assertion_content_comment('oboGo_LAlaninemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-alanine",",","the","L-enantiomer","of","2-aminopropanoic","acid",",","i.e",".","(","2S",")","-2-aminopropanoic","acid","."),4238768). assertion_content_comment('oboGo_LAlanineoxidationtodLactateandammonia',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-alanine","to","D-lactate","and","ammonia","."),4241295). assertion_content_comment('oboGo_LAlanineoxidationtopyruvateviadAlanine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-alanine","to","pyruvate",",","with","D-alanine","as","an","intermediate","."),4241049). assertion_content_comment('oboGo_LAlaninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-alanine","from","one","side","of","a","membrane","to","the","other",".","L-alanine","is","the","L-enantiomer","of","2-aminopropanoic","acid","."),4297418). assertion_content_comment('oboGo_LAlaninetransport',s("The","directed","movement","of","L-alanine",",","the","L-enantiomer","of","2-aminopropanoic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4293740). assertion_content_comment('oboGo_LAlloThreoninealdolaseactivity',s("Catalysis","of","the","reaction",":","L-allo-threonine","=","glycine","+","acetaldehyde","."),4252343). assertion_content_comment('oboGo_LambdaCarrageenaseactivity',s("Catalysis","of","the","endohydrolysis","of","beta-1",",","4-linkages","in","the","backbone","of","lambda-carrageenan",",","resulting","in","the","tetrasaccharide","alpha-D-Galp2",",","6S2-","(","1-","&","gt",";","3",")","-beta-D-Galp2S-","(","1-","&","gt",";","4",")","-alpha-D-Galp2",",","6S2-","(","1-","&","gt",";","3",")","-D-Galp2S","."),4344519). assertion_content_comment('oboGo_Laminin_10Complex',s("A","laminin","complex","composed","of","alpha5",",","beta1","and","gamma1","polypeptide","chains","."),4318500). assertion_content_comment('oboGo_Laminin_11Complex',s("A","laminin","complex","composed","of","alpha5",",","beta2","and","gamma1","polypeptide","chains","."),4318482). assertion_content_comment('oboGo_Laminin_12Complex',s("A","laminin","complex","composed","of","alpha2",",","beta1","and","gamma3","polypeptide","chains","."),4318491). assertion_content_comment('oboGo_Laminin_1Binding',s("Interacting","selectively","and","non-covalently","with","laminin-1",",","a","glycoprotein","trimer","with","the","subunit","composition","alpha1",",","beta1",",","gamma1","."),4318564). assertion_content_comment('oboGo_Laminin_1Complex',s("A","laminin","complex","composed","of","alpha1",",","beta1","and","gamma1","polypeptide","chains","."),4220066). assertion_content_comment('oboGo_Laminin_2Binding',s("Interacting","selectively","and","non-covalently","with","laminin-2",",","a","glycoprotein","trimer","with","the","subunit","composition","alpha2",",","beta1",",","gamma","1","."),4318573). assertion_content_comment('oboGo_Laminin_2Complex',s("A","laminin","complex","composed","of","alpha2",",","beta1","and","gamma1","polypeptide","chains","."),4220057). assertion_content_comment('oboGo_Laminin_3Complex',s("A","laminin","complex","composed","of","alpha1",",","beta2","and","gamma1","polypeptide","chains","."),4220084). assertion_content_comment('oboGo_Laminin_4Binding',s("Interacting","selectively","and","non-covalently","with","laminin-4",",","a","glycoprotein","trimer","with","the","subunit","composition","alpha2",",","beta2",",","gamma","1","."),4318582). assertion_content_comment('oboGo_Laminin_4Complex',s("A","laminin","complex","composed","of","alpha2",",","beta2","and","gamma1","polypeptide","chains","."),4220075). assertion_content_comment('oboGo_Laminin_5Complex',s("A","laminin","complex","composed","of","alpha3",",","beta3","and","gamma2","polypeptide","chains","."),4220028). assertion_content_comment('oboGo_Laminin_6Complex',s("A","laminin","complex","composed","of","alpha3",",","beta1","and","gamma1","polypeptide","chains","."),4220037). assertion_content_comment('oboGo_Laminin_7Complex',s("A","laminin","complex","composed","of","alpha3",",","beta2","and","gamma1","polypeptide","chains","."),4220046). assertion_content_comment('oboGo_Laminin_8Complex',s("A","laminin","complex","composed","of","alpha4",",","beta1","and","gamma1","polypeptide","chains","."),4318401). assertion_content_comment('oboGo_Laminin_9Complex',s("A","laminin","complex","composed","of","alpha4",",","beta2","and","gamma1","polypeptide","chains","."),4318410). assertion_content_comment('oboGo_LAminoAcidalphaLigaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","an","L-amino","acid","+","an","L-amino","acid","=","ADP","+","phosphate","+","L-aminoacyl-L-amino","acid","."),4361080). assertion_content_comment('oboGo_LAminoAciddehydrogenaseactivity',s("Catalysis","of","the","reaction",":","an","L-amino","acid","+","H2O","+","NAD","+","=","a","2-oxo","acid","+","NH3","+","NADH","."),4269978). assertion_content_comment('oboGo_LAminoacideffluxtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","an","L-amino","acid","from","the","inside","of","the","cell","to","the","outside","of","the","cell","across","a","membrane","."),4290338). assertion_content_comment('oboGo_LAminoacidimport',s("The","directed","movement","of","L-enantiomer","amino","acids","into","a","cell","or","organelle","."),4035092). assertion_content_comment('oboGo_LAminoAcidoxidaseactivity',s("Catalysis","of","the","reaction",":","a","L-amino","acid","+","H2O","+","O2","=","a","2-oxo","acid","+","NH3","+","hydrogen","peroxide","."),4383336). assertion_content_comment('oboGo_LAminoacidtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","an","L-amino","acid","from","one","side","of","a","membrane","to","the","other",".","L-amino","acids","are","the","L-enantiomers","of","amino","acids","."),4215599). assertion_content_comment('oboGo_LAminoacidtransport',s("The","directed","movement","of","L-enantiomer","amino","acids","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4035089). assertion_content_comment('oboGo_LAminoadipateSemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-2-aminoadipate","6-semialdehyde","+","NADP","+","+","H2O","=","L-2-aminoadipate","+","NADPH","+","H","+"),4213502). assertion_content_comment('oboGo_LanosterolOAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","lanosterol","=","CoA","+","lanosterol","ester","."),4349389). assertion_content_comment('oboGo_LArabinitol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-arabinitol","+","NAD","(","+",")","=","L-ribulose","+","H","(","+",")","+","NADH","."),4364484). assertion_content_comment('oboGo_LArabinitol4Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-arabinitol","+","NAD","(","+",")","=","L-xylulose","+","H","(","+",")","+","NADH","."),4270002). assertion_content_comment('oboGo_LArabinokinaseactivity',s("Catalysis","of","the","reaction",":","L-arabinose","+","ATP","=","beta-L-arabinose","1-phosphate","+","ADP","+","2","H","(","+",")"),4260720). assertion_content_comment('oboGo_LArabinonatedehydrataseactivity',s("Catalysis","of","the","reaction",":","L-arabinonate","=","2-dehydro-3-deoxy-L-arabinonate","+","H","(","2",")","O","."),4269932). assertion_content_comment('oboGo_LArabinonolactonaseactivity',s("Catalysis","of","the","reaction",":","L-arabinono-1",",","4-lactone","+","H","(","2",")","O","=","L-arabinonate","+","H","(","+",")"),4269945). assertion_content_comment('oboGo_LArabinose1Dehydrogenasenadactivity',s("Catalysis","of","the","reaction",":","L-arabinose","+","NAD","+","=","L-arabinono-1",",","4-lactone","+","NADH","."),4269955). assertion_content_comment('oboGo_LArabinose1Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","L-arabinose","+","NADP","+","=","L-arabinono-1",",","4-lactone","+","NADPH","+","H","+"),4288454). assertion_content_comment('oboGo_LArabinosebetaDThiogalactopyranoside_Hydrogenantiporteractivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","H","+","(","out",")","+","(","L-arabinose","or","beta-D-thiogalactopyranoside",")","(","in",")","=","H","+","(","in",")","+","(","L-arabinose","or","beta-D-thiogalactopyranoside",")","(","out",")"),4292993). assertion_content_comment('oboGo_LArabinosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-arabinose",",","arabino-pentose","."),4338788). assertion_content_comment('oboGo_LArabinosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-arabinose",",","the","L-enantiomer","of","arabino-pentose","."),4242812). assertion_content_comment('oboGo_LArabinosecatabolicprocessto2Oxoglutarate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-arabinose","into","other","compounds",",","including","2-oxoglutarate","."),4243275). assertion_content_comment('oboGo_LArabinosecatabolicprocesstoxylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-arabinose","into","other","compounds",",","including","xylulose","5-phosphate","."),4242818). assertion_content_comment('oboGo_LArabinoseImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","L-arabinose","(","out",")","=","ADP","+","phosphate","+","L-arabinose","(","in",")"),4289687). assertion_content_comment('oboGo_LArabinoseisomeraseactivity',s("Catalysis","of","the","reaction",":","L-arabinose","=","L-ribulose","."),4252376). assertion_content_comment('oboGo_LArabinosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-arabinose",",","the","D-enantiomer","of","arabino-pentose",".","L-arabinose","occurs","free",",","e.g",".","in","the","heartwood","of","many","conifers",",","and","in","the","combined","state",",","in","both","furanose","and","pyranose","forms",",","as","a","constituent","of","various","plant","hemicelluloses",",","bacterial","polysaccharides","etc","."),4242809). assertion_content_comment('oboGo_LArabinose_Nadpreductaseactivity',s("Catalysis","of","the","reaction",":","L-arabitol","+","NADP","+","=","L-arabinose","+","NADPH","+","H","+"),4337348). assertion_content_comment('oboGo_LArabinosetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-arabinose","from","one","side","of","the","membrane","to","the","other",".","Arabinose","occurs","free",",","for","example","in","the","heartwood","of","many","conifers","and","in","the","combined","states",",","in","both","furanose","and","pyranose","forms",",","as","a","constituent","of","various","plant","hemicelluloses",",","bacterial","polysaccharides",",","etc","."),4289682). assertion_content_comment('oboGo_LArabinosetransport',s("The","directed","movement","of","L-arabinose",",","the","L-enantiomer","of","arabinose",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4314998). assertion_content_comment('oboGo_LArabitolcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-arabitol",",","the","pentitol","derived","from","arabinose","or","lyxose","by","reduction","of","the","aldehyde","group","."),4243470). assertion_content_comment('oboGo_LArabitolcatabolicprocesstoxylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-arabitol","to","form","xylulose","5-phosphate",".","L-arabitol","is","converted","into","L-xylulose",",","which","is","then","phosphorylated","to","L-xylulose-5-phosphate",".","This","is","converted","to","D-xylulose-5-phosphate","via","the","intermediate","L-ribulose-5-phosphate","."),4243476). assertion_content_comment('oboGo_LArabitolmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-arabitol",",","the","pentitol","derived","from","arabinose","or","lyxose","by","reduction","of","the","aldehyde","group","."),4243467). assertion_content_comment('oboGo_LargeConductanceCalciumActivatedpotassiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","potassium","by","a","channel","with","a","unit","conductance","of","100","to","220","picoSiemens","that","opens","in","response","to","stimulus","by","concerted","actions","of","internal","calcium","ions","and","membrane","potential",".","Large","conductance","calcium-activated","potassium","channels","are","less","sensitive","to","calcium","than","are","small","or","intermediate","conductance","calcium-activated","potassium","channels",".","Transport","by","a","channel","involves","catalysis","of","facilitated","diffusion","of","a","solute","(","by","an","energy-independent","process",")","involving","passage","through","a","transmembrane","aqueous","pore","or","channel",",","without","evidence","for","a","carrier-mediated","mechanism","."),4159421). assertion_content_comment('oboGo_LArginineimport',s("The","directed","movement","of","L-arginine",",","the","L-enantiomer","of","2-amino-5-guanidinopentanoic","acid",",","into","a","cell","or","organelle","."),4035095). assertion_content_comment('oboGo_LariatFormation5Splicesitecleavage',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4224267). assertion_content_comment('oboGo_Laricitrin5OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","laricitrin","=","S-adenosyl-L-homocysteine","+","syringetin","."),4175359). assertion_content_comment('oboGo_LarvalChitinBasedcuticledevelopment',s("Synthesis","and","deposition","of","a","chitin-based","larval","cuticle",".","The","insect","larval","cuticle","is","a","secretion","from","epidermal","cells","that","is","shed","at","each","molt",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4020655). assertion_content_comment('oboGo_LarvalSerumProtein_1',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4219998). assertion_content_comment('oboGo_LAscorbate6Phosphatelactonaseactivity',s("Catalysis","of","the","reaction",":","L-ascorbate","6-phosphate","+","H2O","=","3-keto-L-gulonate","6-phosphate","."),4375806). assertion_content_comment('oboGo_LAscorbateCytochromeB5reductaseactivity',s("Catalysis","of","the","reaction",":","ferricytochrome","B5","+","ascorbate","=","ferrocytochrome","B5","+","monodehydroascorbate","."),4364714). assertion_content_comment('oboGo_LAscorbateoxidaseactivity',s("Catalysis","of","the","reaction",":","2","L-ascorbate","+","O2","=","2","dehydroascorbate","+","2","H2O","."),4253831). assertion_content_comment('oboGo_LAscorbateperoxidaseactivity',s("Catalysis","of","the","reaction",":","L-ascorbate","+","hydrogen","peroxide","=","dehydroascorbate","+","2","H2O","."),4306065). assertion_content_comment('oboGo_LAscorbate_Sodiumsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ascorbate","(","out",")","+","Na","+","(","out",")","=","ascorbate","(","in",")","+","Na","+","(","in",")"),4255013). assertion_content_comment('oboGo_LAscorbicacidbinding',s("Interacting","selectively","and","non-covalently","with","L-ascorbic","acid",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",";","L-ascorbic","acid","is","vitamin","C","and","has","co-factor","and","anti-oxidant","activities","in","many","species","."),4319470). assertion_content_comment('oboGo_LAscorbicacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-ascorbic","acid",";","L-ascorbic","acid","ionizes","to","give","L-ascorbate",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",",","which","is","required","as","a","cofactor","in","the","oxidation","of","prolyl","residues","to","hydroxyprolyl",",","and","other","reactions","."),4138316). assertion_content_comment('oboGo_LAscorbicacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-ascorbic","acid",";","L-ascorbic","acid","ionizes","to","give","L-ascorbate",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",",","which","is","required","as","a","cofactor","in","the","oxidation","of","prolyl","residues","to","hydroxyprolyl",",","and","other","reactions","."),4233583). assertion_content_comment('oboGo_LAscorbicacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-ascorbic","acid",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",";","L-ascorbic","acid","is","vitamin","C","and","has","co-factor","and","anti-oxidant","activities","in","many","species","."),4138307). assertion_content_comment('oboGo_LAscorbicacidtransporteractivity',s("Enables","the","directed","movement","of","L-ascorbate","into",",","out","of","or","within","a","cell",",","or","between","cells",".","L-ascorbate",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",",","is","vitamin","C","and","has","co-factor","and","anti-oxidant","activities","in","many","species","."),4178441). assertion_content_comment('oboGo_LAscorbicacidtransport',s("The","directed","movement","of","L-ascorbic","acid","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","L-ascorbate",",","(","2R",")","-2-","[","(","1S",")","-1",",","2-dihydroxyethyl","]","-4-hydroxy-5-oxo-2",",","5-dihydrofuran-3-olate",",","is","vitamin","C","and","has","co-factor","and","anti-oxidant","activities","in","many","species","."),4178168). assertion_content_comment('oboGo_LAsparaginebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","asparagine",",","(","2S",")","-2-amino-3-carbamoylpropanoic","acid","."),4177658). assertion_content_comment('oboGo_LAsparaginemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-asparagine",",","(","2S",")","-2-amino-3-carbamoylpropanoic","acid","."),4177631). assertion_content_comment('oboGo_LAsparaginetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-asparagine","from","one","side","of","a","membrane","to","the","other",".","L-asparagine","is","the","L-enantiomer","of","alpha-aminosuccinamic","acid","."),4296341). assertion_content_comment('oboGo_LAspartate_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","+","2-oxoglutarate","=","oxaloacetate","+","L-glutamate","."),4212821). assertion_content_comment('oboGo_LAspartate_Fumarateoxidoreductaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","+","fumarate","=","alpha-iminosuccinate","+","succinate","."),4287751). assertion_content_comment('oboGo_LAspartateoxidaseactivity',s("Catalysis","of","the","reaction",":","L-aspartate","+","O2","=","iminosuccinate","+","hydrogen","peroxide","."),4252365). assertion_content_comment('oboGo_LAspartatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-aspartate","from","one","side","of","a","membrane","to","the","other",".","L-aspartate","is","the","anion","derived","from","aspartic","acid","."),4289856). assertion_content_comment('oboGo_LAspartatetransport',s("The","directed","movement","of","L-aspartate",",","the","L-enantiomer","of","the","anion","of","(","2R",")","-2-aminobutanedioic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4176468). assertion_content_comment('oboGo_LatiaLuciferinmonooxygenasedemethylatingactivity',s("Catalysis","of","the","reaction",":","2","O2","+","donor-H2","+","Latia","luciferin","=","light","+","H2O","+","acceptor","+","formate","+","CO2","+","oxidized","Latia","luciferin","."),4364652). assertion_content_comment('oboGo_LCysteatesulfoLyaseactivity',s("Catalysis","of","the","reaction",":","L-cysteate","+","H","(","2",")","O","=","NH","(","4",")","(","+",")","+","pyruvate","+","sulfite","."),4360645). assertion_content_comment('oboGo_LCysteine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-cysteine","+","2-oxoglutarate","=","mercaptopyruvate","+","L-glutamate","."),4375369). assertion_content_comment('oboGo_LCysteinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-cysteine",",","the","L-enantiomer","of","2-amino-3-mercaptopropanoic","acid",",","i.e",".","(","2R",")","-2-amino-3-mercaptopropanoic","acid","."),4241613). assertion_content_comment('oboGo_LCysteinecatabolicprocesstohypotaurine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-cysteine","into","other","compounds",",","including","hypotaurine","."),4241912). assertion_content_comment('oboGo_LCysteinecatabolicprocesstopyruvate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-cysteine","into","other","compounds",",","including","pyruvate","."),4241664). assertion_content_comment('oboGo_LCysteinecatabolicprocesstopyruvateusingcysteinedioxygenase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","into","pyruvate","of","L-cystine",",","catalyzed","by","the","enzyme","cysteine","dioxygenase","(","EC",":","1.13.11.20",")"),4241668). assertion_content_comment('oboGo_LCysteinecatabolicprocesstotaurine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-cysteine","into","other","compounds",",","including","taurine","."),4241643). assertion_content_comment('oboGo_LCysteinecatabolicprocessviacystine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-cysteine",",","via","the","intermediate","cystine","."),4241618). assertion_content_comment('oboGo_LCysteinecatabolicprocessviacystineusingcysteinetransaminase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown",",","via","the","compound","cystine",",","of","L-cysteine",",","catalyzed","by","the","enzyme","cysteine","transaminase","(","EC",":","2.6.1.3",")"),4241708). assertion_content_comment('oboGo_LCysteinecatabolicprocessviacystineusingcystinereductase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown",",","via","the","compound","cystine",",","of","L-cysteine",",","catalyzed","by","the","enzyme","cystine","reductase","(","EC",":","1.8.1.6",")"),4241720). assertion_content_comment('oboGo_LCysteinecatabolicprocessviacystineusingglutathioneCystinetranshydrogenase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown",",","via","the","compound","cystine",",","of","L-cysteine",",","catalyzed","by","the","enzyme","glutathione-cystine","transhydrogenase","(","EC",":","1.8.4.4",")"),4241732). assertion_content_comment('oboGo_LCysteinedesulfhydraseactivity',s("Catalysis","of","the","reaction",":","L-cysteine","+","H2O","=","ammonia","+","pyruvate","+","hydrogen","sulfide","+","H","+"),4181069). assertion_content_comment('oboGo_LCysteinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-cysteine",",","the","L-enantiomer","of","2-amino-3-mercaptopropanoic","acid",",","i.e",".","(","2R",")","-2-amino-3-mercaptopropanoic","acid","."),4241610). assertion_content_comment('oboGo_LCystinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-cystine","from","one","side","of","a","membrane","to","the","other","."),4289799). assertion_content_comment('oboGo_LCystinetransport',s("The","directed","movement","of","L-cystine","(","also","known","as","dicysteine",")","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4293696). assertion_content_comment('oboGo_LDiaminopimelatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-diaminopimelate","from","one","side","of","a","membrane","to","the","other",".","L-diaminopimelate","is","the","L-enantiomer","anion","of","2",",","6-diaminoheptanedioic","acid","."),4289428). assertion_content_comment('oboGo_LDopabinding',s("Interacting","selectively","with","L-DOPA",",","the","modified","amino","acid","(","2S",")","-2-amino-3-","(","3",",","4-dihydroxyphenyl",")","propanoic","acid","."),4157084). assertion_content_comment('oboGo_LDopareceptoractivity',s("Combining","with","L-DOPA","to","initiate","a","change","in","cell","activity",".","L-DOPA","is","the","modified","amino","acid","(","2S",")","-2-amino-3-","(","3",",","4-dihydroxyphenyl",")","propanoic","acid",",","and","is","the","precursor","to","dopamine",",","norepinephrine","(","noradrenaline",")","and","epinephrine","."),4379963). assertion_content_comment('oboGo_LeftHandedzDnabinding',s("Interacting","selectively","and","non-covalently","with","DNA","in","the","Z","form",",","i.e",".","a","left-handed","helix","in","which","the","phosphate","backbone","zigzags","."),4193340). assertion_content_comment('oboGo_LensDevelopmentInCameraTypeeye',s("The","process","whose","specific","outcome","is","the","progression","of","the","lens","over","time",",","from","its","formation","to","the","mature","structure",".","The","lens","is","a","transparent","structure","in","the","eye","through","which","light","is","focused","onto","the","retina",".","An","example","of","this","process","is","found","in","Mus","musculus","."),3989778). assertion_content_comment('oboGo_LensInductionInCameraTypeeye',s("Signaling","at","short","range","between","the","head","ectoderm","and","the","optic","vesicle","that","results","in","the","head","ectoderm","forming","a","lens","."),4115304). assertion_content_comment('oboGo_LensMorphogenesisInCameraTypeeye',s("The","process","in","which","the","anatomical","structures","of","the","lens","are","generated","and","organized",".","The","lens","is","a","transparent","structure","in","the","eye","through","which","light","is","focused","onto","the","retina",".","An","example","of","this","process","is","found","in","Mus","musculus","."),3989804). assertion_content_comment('oboGo_LeptinMediatedsignalingpathway',s("A","series","of","molecular","signals","generated","as","a","consequence","of","leptin","binding","to","a","cell","surface","receptor","."),4338063). assertion_content_comment('oboGo_L_Erythro_35_DiaminohexanoateDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","(","3S",",","5S",")","-3",",","5-diaminohexanoate","+","H","(","2",")","O","+","NAD","(","+",")","=","(","S",")","-5-amino-3-oxo-hexanoate","+","H","(","+",")","+","NADH","+","NH","(","4",")","(","+",")"),4365779). assertion_content_comment('oboGo_L_Erythro_3_Methylmalyl_CoADehydrataseActivity',s("Catalysis","of","the","reaction",":","L-erythro-3-methylmalyl-CoA","=","mesaconyl-CoA","+","H2O","."),4328180). assertion_content_comment('oboGo_L_Erythro_3_Methylmalyl_CoALyaseActivity',s("Catalysis","of","the","reaction",":","propionyl-CoA","+","glyoxylate","=","L-erythro-3-methylmalyl-CoA","."),4328155). assertion_content_comment('oboGo_Leucine23Aminomutaseactivity',s("Catalysis","of","the","reaction",":","L-leucine","=","(","3R",")","-beta-leucine","."),4270184). assertion_content_comment('oboGo_LeucineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-leucine","+","acetyl-CoA","=","N-acetyl-L-leucine","+","CoA","+","H","(","+",")"),4270094). assertion_content_comment('oboGo_LeucineRichgProteinreceptorLikereceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4383886). assertion_content_comment('oboGo_LeucineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","L-leucine","+","ATP","+","tRNA","(","Leu",")","=","AMP","+","diphosphate","+","2","H","(","+",")","+","Leu-tRNA","(","Leu",")"),4199898). assertion_content_comment('oboGo_LeucylTrnaaminoacylation',s("The","process","of","coupling","leucine","to","leucyl-tRNA",",","catalyzed","by","leucyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179719). assertion_content_comment('oboGo_LeukocyteActivationDependentarrest',s("The","formation","of","an","integrin-dependent","strong","adhesive","bond","between","leukocytes","and","blood","vessel","endothelial","cells","which","is","dependent","on","prior","activation","of","the","leukocyte","and","leads","to","the","firm","attachment","of","the","leukocyte","to","the","endothelial","surface",",","typically","the","third","step","in","cellular","extravasation","."),4100907). assertion_content_comment('oboGo_LeukocyteCellCelladhesion',s("The","attachment","of","a","leukocyte","to","another","cell","via","adhesion","molecules","."),4100892). assertion_content_comment('oboGo_LeukotrieneA4hydrolaseactivity',s("Catalysis","of","the","reaction",":","H","(","2",")","O","+","leukotriene","A","(","4",")","=","leukotriene","B","(","4",")"),4205813). assertion_content_comment('oboGo_LeukotrieneB420Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","6Z",",","8E",",","10E",",","14Z",")","-","(","5S",",","12R",")","-5",",","12-dihydroxyicosa-6",",","8",",","10",",","14-tetraenoate","+","NADPH","+","H2O","=","(","6Z",",","8E",",","10E",",","14Z",")","-","(","5S",",","12R",")","-5",",","12",",","20-trihydroxyicosa-6",",","8",",","10",",","14-tetraenoate","+","NADP","+","+","H2O","."),4270062). assertion_content_comment('oboGo_LeukotrieneC4synthaseactivity',s("Catalysis","of","the","reaction",":","leukotriene","C","(","4",")","=","glutathione","+","leukotriene","A","(","4",")"),4205772). assertion_content_comment('oboGo_LeukotrieneE420Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","H","(","+",")","+","leukotriene","E","(","4",")","+","NADPH","+","O","(","2",")","=","20-hydroxy-leukotriene","E","(","4",")","+","H","(","2",")","O","+","NADP","(","+",")"),4270081). assertion_content_comment('oboGo_LevanFructotransferaseDFAIvFormingactivity',s("Catalysis","of","the","production","of","di-beta-D-fructofuranose","2",",","6","'",":","2","'",",","6-dianhydride","(","DFA","IV",")","by","successively","eliminating","the","diminishing","(","2-","&","gt",";","6",")","-beta-D-fructan","(","levan",")","chain","from","the","terminal","D-fructosyl-D-fructosyl","disaccharide","."),4345251). assertion_content_comment('oboGo_LFuconatedehydrataseactivity',s("Catalysis","of","the","reaction",":","L-fuconate","=","2-dehydro-3-deoxy-L-fuconate","+","H","(","2",")","O","."),4269966). assertion_content_comment('oboGo_LFucosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-fucose","(","6-deoxy-L-galactose",")"),4225168). assertion_content_comment('oboGo_LFucosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-fucose","(","6-deoxy-Lgalactose",")"),4313022). assertion_content_comment('oboGo_LFucoseisomeraseactivity',s("Catalysis","of","the","reaction",":","L-fucose","=","L-fuculose","."),4252388). assertion_content_comment('oboGo_LFucosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-fucose",",","6-deoxy-L-galactose",",","a","sugar","that","occurs","in","fucans",",","a","class","of","polysaccharides","in","seaweeds",",","especially","Fucus","species",",","and","in","the","cell","wall","matrix","of","higher","plants","."),4225165). assertion_content_comment('oboGo_LFuculokinaseactivity',s("Catalysis","of","the","reaction",":","L-fuculose","+","ATP","=","L-fuculose","1-phosphate","+","ADP","+","2","H","(","+",")"),4252428). assertion_content_comment('oboGo_LFuculosePhosphatealdolaseactivity',s("Catalysis","of","the","reaction",":","L-fuculose","1-phosphate","=","(","S",")","-lactaldehyde","+","glycerone","phosphate","."),4252413). assertion_content_comment('oboGo_LGalactonatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-galactonate",",","the","anion","of","L-galactonic","acid","."),4359442). assertion_content_comment('oboGo_LGalactonatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-galactonate",",","the","anion","of","L-galactonic","acid","."),4359380). assertion_content_comment('oboGo_LGalactonolactoneoxidaseactivity',s("Catalysis","of","the","reaction",":","L-galactono-1",",","4-lactone","+","O","(","2",")","=","L-ascorbate","+","H","(","2",")","O","(","2",")","+","H","(","+",")"),4269920). assertion_content_comment('oboGo_L_Galactose_1_PhosphatePhosphataseActivity',s("Catalysis","of","the","reaction",":","L-galactose-1-phosphate","+","H2O","=","L-galactose","+","phosphate","."),4331898). assertion_content_comment('oboGo_LGalactosedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-galactose","+","NAD","+","=","L-galactono-1",",","4-lactone","+","NADH","+","H","+"),4331917). assertion_content_comment('oboGo_LGammaAminobutyricacidtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-gamma-aminobutyric","acid","from","one","side","of","a","membrane","to","the","other",".","L-gamma-aminobutyric","acid","is","4-aminobutyrate","(","GABA",")"),4216258). assertion_content_comment('oboGo_LGlucuronatereductaseactivity',s("Catalysis","of","the","reaction",":","L-gulonate","+","NADP","(","+",")","=","D-glucuronate","+","H","(","+",")","+","NADPH","."),4377265). assertion_content_comment('oboGo_LGlutamateimport',s("The","directed","movement","of","L-glutamate",",","the","L-enantiomer","of","the","anion","of","2-aminopentanedioic","acid",",","into","a","cell","or","organelle","."),4120505). assertion_content_comment('oboGo_LGlutamateoxidaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","O2","+","H2O","=","2-oxoglutarate","+","NH3","+","H2O2","."),4269903). assertion_content_comment('oboGo_LGlutamatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-glutamate","from","one","side","of","a","membrane","to","the","other",".","L-glutamate","is","the","anion","of","2-aminopentanedioic","acid","."),4216035). assertion_content_comment('oboGo_LGlutamatetransport',s("The","directed","movement","of","L-glutamate",",","the","L","enantiomer","anion","of","2-aminopentanedioic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),3990610). assertion_content_comment('oboGo_LGlutamine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-glutamine","+","2-oxoglutarate","=","2-oxoglutaramate","+","L-glutamate","."),4181534). assertion_content_comment('oboGo_LGlutamineaminotransferaseactivity',s("Catalysis","of","the","transfer","of","an","amino","group","from","L-glutamine","to","an","acceptor",",","usually","a","2-oxo","acid","."),4174590). assertion_content_comment('oboGo_LGlutamine_Pyruvateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-glutamine","+","pyruvate","=","2-oxoglutaramate","+","L-alanine","."),4377515). assertion_content_comment('oboGo_LGlutaminetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-glutamine","from","one","side","of","a","membrane","to","the","other",".","L-glutamine","is","2-amino-4-carbamoylbutanoic","acid","."),4293642). assertion_content_comment('oboGo_LGlycoldehydrogenaseactivity',s("Catalysis","of","the","reaction",":","an","L-glycol","+","NAD","(","P",")","+","=","a","2-hydroxycarbonyl","compound","+","NAD","(","P",")","H","+","H","+"),4269889). assertion_content_comment('oboGo_LGulonate3Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-gulonate","+","NAD","(","+",")","=","3-dehydro-L-gulonate","+","H","(","+",")","+","NADH","."),4272011). assertion_content_comment('oboGo_L_Gulono_14_LactoneDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","L-gulono-1",",","4-lactone","+","2","ferricytochrome","c","=","L-ascorbate","+","2","ferrocytochrome","c","."),4181984). assertion_content_comment('oboGo_LGulonolactoneoxidaseactivity',s("Catalysis","of","the","reaction",":","L-gulono-1",",","4-lactone","+","O2","=","L-xylo-hex-3-ulonolactone","+","H2O2","."),4271973). assertion_content_comment('oboGo_LHistidine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-histidine","=","3-","(","imidazol-5-yl",")","pyruvate","+","L-glutamate","."),4246228). assertion_content_comment('oboGo_LHistidinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-histidine","from","one","side","of","a","membrane","to","the","other",".","L-histidine","is","2-amino-3-","(","1H-imidazol-4-yl",")","propanoic","acid","."),4215893). assertion_content_comment('oboGo_LHomocysteinebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-homocysteine",",","the","L-enantiomer","of","2-amino-4-sulfanylbutanoic","acid","."),4166594). assertion_content_comment('oboGo_LHydroxyprolinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-hydroxyproline","from","one","side","of","a","membrane","to","the","other","."),4352506). assertion_content_comment('oboGo_Licodione2OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","licodione","=","2","'","-O-methyllicodione","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308827). assertion_content_comment('oboGo_LIditol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-iditol","+","NAD","+","=","L-sorbose","+","NADH","+","H","+"),4185890). assertion_content_comment('oboGo_LIdonate2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-idonate","+","NADP","+","=","5-dehydro-D-gluconate","+","NADPH","."),4269873). assertion_content_comment('oboGo_LIdonate5Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-idonate","+","NAD","(","P",")","+","=","5-dehydrogluconate","+","NAD","(","P",")","H","+","H","+"),4268570). assertion_content_comment('oboGo_LIdonatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-idonate",",","the","anion","of","idonic","acid",",","an","aldonic","acid","derived","from","L-idose",",","an","aldohexose","which","is","epimeric","with","D-glucose","."),4351700). assertion_content_comment('oboGo_LIdonatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-idonate",",","the","anion","of","idonic","acid",",","an","aldonic","acid","derived","from","L-idose",",","an","aldohexose","which","is","epimeric","with","D-glucose","."),4351671). assertion_content_comment('oboGo_LIdonatedGluconate_Hydrogensymporteractivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","(","L-idonate","or","D-gluconate",")","(","out",")","+","H","+","(","out",")","=","(","L-iodonate","or","D-gluconate",")","(","in",")","+","H","+","(","in",")"),4293485). assertion_content_comment('oboGo_LIdonatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-idonate",",","the","anion","of","idonic","acid",",","an","aldonic","acid","derived","from","L-idose",",","an","aldohexose","which","is","epimeric","with","D-glucose","."),4242513). assertion_content_comment('oboGo_LIdonatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-idonate","from","one","side","of","the","membrane","to","the","other",".","L-idonate","is","an","aldonic","acid","derived","from","L-idose",",","an","aldohexose","which","is","epimeric","with","D-glucose","."),4293450). assertion_content_comment('oboGo_LIdonatetransport',s("The","directed","movement","of","L-idonate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","L-idonate","is","an","aldonic","acid","derived","from","L-idose",",","an","aldohexose","which","is","epimeric","with","D-glucose","."),4290845). assertion_content_comment('oboGo_LIduronidaseactivity',s("Catalysis","of","the","hydrolysis","of","alpha-L-iduronosidic","linkages","in","dermatan","sulfate","."),4185859). assertion_content_comment('oboGo_LigandDependentnuclearreceptoractivity',s("A","ligand-dependent","receptor","found","in","the","nucleus","of","the","cell","."),4192859). assertion_content_comment('oboGo_LigandDependentnuclearreceptorbinding',s("Interacting","selectively","and","non-covalently",",","in","a","ligand","dependent","manner",",","with","a","nuclear","receptor","protein","."),4302067). assertion_content_comment('oboGo_LigandDependentnuclearreceptortranscriptioncoactivatoractivity',s("The","function","of","a","transcription","cofactor","that","activates","transcription","in","conjuction","with","a","ligand-dependent","nuclear","receptor","from","a","RNA","polymerase","II","promoter",";","does","not","bind","DNA","itself","."),4309729). assertion_content_comment('oboGo_LigandDependentthyroidhormonereceptorinteractoractivity',s("OBSOLETE",".","Ligand","dependent","interaction","with","the","thyroid","hormone","receptor","."),4302057). assertion_content_comment('oboGo_LigandGatedchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","solute","by","a","channel","that","opens","when","a","specific","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158392). assertion_content_comment('oboGo_LigandGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","when","a","specific","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158394). assertion_content_comment('oboGo_LigandGatedsodiumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","sodium","ion","by","a","channel","that","opens","when","a","specific","ligand","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4295131). assertion_content_comment('oboGo_LigandRegulatedtranscriptionfactoractivity',s("Functions","to","enable","the","transcription","of","specific",",","or","specific","sets",",","of","genes","by","RNA","polymerase","II","in","response","to","a","ligand","."),4192802). assertion_content_comment('oboGo_LigaseActivityFormingAminoacylTrnaandrelatedcompounds',s("Catalysis","of","the","joining","of","an","amino","acid","and","a","nucleic","acid","(","usually","tRNA",")","or","poly","(","ribitol","phosphate",")",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate",".","The","reaction","forms","an","aminoacyl-tRNA","or","a","related","compound","."),4199082). assertion_content_comment('oboGo_LigaseActivityFormingCarbonCarbonbonds',s("Catalysis","of","the","joining","of","two","molecules","via","a","carbon-carbon","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4186565). assertion_content_comment('oboGo_LigaseActivityFormingCarbonNitrogenbonds',s("Catalysis","of","the","joining","of","two","molecules",",","or","two","groups","within","a","single","molecule",",","via","a","carbon-nitrogen","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4155382). assertion_content_comment('oboGo_LigaseActivityFormingCarbonOxygenbonds',s("Catalysis","of","the","joining","of","two","molecules","via","a","carbon-oxygen","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4199080). assertion_content_comment('oboGo_LigaseActivityFormingCarbonSulfurbonds',s("Catalysis","of","the","joining","of","two","molecules","via","a","carbon-sulfur","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4173839). assertion_content_comment('oboGo_LigaseActivityFormingNitrogenMetalbondsformingcoordinationcomplexes',s("Catalysis","of","the","ligation","of","two","substances","via","a","nitrogen-metal","bond",",","forming","a","coordination","complex","."),4279180). assertion_content_comment('oboGo_LigaseActivityFormingNitrogenMetalbonds',s("Catalysis","of","the","joining","of","a","metal","ion","to","a","molecule","via","a","nitrogen-metal","bond",",","with","the","concomitant","hydrolysis","of","the","diphosphate","bond","in","ATP","or","a","similar","triphosphate","."),4279069). assertion_content_comment('oboGo_LightActivatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","in","response","to","a","light","stimulus","."),4247149). assertion_content_comment('oboGo_LightActivatedvoltageGatedcalciumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","voltage-gated","channel","that","is","activated","in","response","to","light",".","A","voltage-gated","channel","is","a","channel","whose","open","state","is","dependent","on","the","voltage","across","the","membrane","in","which","it","is","embedded","."),4247151). assertion_content_comment('oboGo_LightActivatedvoltageGatedcalciumchannelcomplex',s("A","protein","complex","that","forms","a","transmembrane","channel","through","which","calcium","ions","may","cross","a","cell","membrane","in","response","to","changes","in","membrane","potential","generated","in","response","to","a","light","stimulus","."),4247173). assertion_content_comment('oboGo_LightDrivenactivetransmembranetransporteractivity',s("Primary","active","transport","of","a","solute","across","a","membrane",",","driven","by","light",".","Primary","active","transport","is","catalysis","of","the","transport","of","a","solute","across","a","membrane",",","up","the","solute","'","s","concentration","gradient",",","by","binding","the","solute","and","undergoing","a","series","of","conformational","changes",".","Transport","works","equally","well","in","either","direction","and","is","driven","by","a","primary","energy","source","."),4291749). assertion_content_comment('oboGo_LightDrivenprotontransport',s("The","transport","of","protons","against","an","electrochemical","gradient",",","using","energy","from","light","."),4295048). assertion_content_comment('oboGo_LightHarvestingcomplexcorecomplex',s("Light","harvesting","complex","associated","with","the","reaction","complex","of","photosynthetic","purple","bacteria","."),4052910). assertion_content_comment('oboGo_LightHarvestingcomplexperipheralcomplex',s("Bacteriochlorophyll","a","binding","complex","that","is","peripherally","associated","to","the","bacterial","reaction","center","."),4052846). assertion_content_comment('oboGo_LightHarvestingcomplex',s("A","protein-pigment","complex","that","may","be","closely","or","peripherally","associated","to","photosynthetic","reaction","centers","that","participate","in","harvesting","and","transferring","radiant","energy","to","the","reaction","center","."),4022713). assertion_content_comment('oboGo_LightInducedreleaseofinternallysequesteredcalciumion',s("The","process","in","which","the","detection","of","light","triggers","the","release","of","internally","sequestered","calcium","ions","."),4021086). assertion_content_comment('oboGo_LignostilbeneAlphaBetaDioxygenaseactivity',s("Catalysis","of","the","reaction",":","1",",","2-bis","(","4-hydroxy-3-methoxyphenyl",")","ethylene","+","O","(","2",")","=","2","vanillin","."),4270144). assertion_content_comment('oboGo_Limonene_12_DiolDehydrogenaseActivity',s("Catalysis","of","the","reaction",":","(","1S",",","2S",",","4R",")","-limonene-1",",","2-diol","+","DCPIP","+","=","DCPIPH","+","H","+","+","(","1S",",","4R",")","-1-hydroxy-2-oxolimonene","."),4277457). assertion_content_comment('oboGo_Limonene_12_EpoxideHydrolaseActivity',s("Catalysis","of","the","reaction",":","limonene-1",",","2-epoxide","+","H2O","=","limonene-1",",","2-diol",".","Other","substrates","include","alicyclic","and","1-methyl-substituted","epoxides",",","such","as","1-methylcyclohexene","oxide",",","indene","oxide","and","cyclohexene","oxide","."),4274986). assertion_content_comment('oboGo_Limonene8Hydrataseactivity',s("Catalysis","of","the","reaction",":","limonene","+","H2O","=","alpha-terpineol","."),4352678). assertion_content_comment('oboGo_Limonene8Monooxygenaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4275456). assertion_content_comment('oboGo_LimoninDRingLactonaseactivity',s("Catalysis","of","the","reaction",":","limonoate","D-ring-lactone","+","H2O","=","limonoate","."),4270105). assertion_content_comment('oboGo_Linalool8Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","AH","(","2",")","+","linalool","+","O","(","2",")","=","(","2E",")","-2",",","6-dimethylocta-2",",","7-diene-1",",","6-diol","+","A","+","H","(","2",")","O","."),4270119). assertion_content_comment('oboGo_Linoleate11Lipoxygenaseactivity',s("Catalysis","of","the","reaction",":","linoleate","+","O","(","2",")","=","(","9Z",",","11S",",","12Z",")","-11-hydroperoxyoctadeca-9",",","12-dienoate","."),4267872). assertion_content_comment('oboGo_LinoleoylCoadesaturaseactivity',s("Catalysis","of","the","reaction",":","linoleoyl-CoA","+","reduced","acceptor","+","O2","=","gamma-linolenoyl-CoA","+","acceptor","+","2","H2O","."),4303914). assertion_content_comment('oboGo_LipidACoreheptosyltransferaseactivity',s("Catalysis","of","the","reaction",":","galactosyl-glucosyl3-heptosyl3-KDO2-lipid","A-bisphosphate","+","ADP-L-glycero-beta-D-manno-heptose","=","lipid","A-core","+","ADP","+","H","+"),4168413). assertion_content_comment('oboGo_LipidADisaccharidesynthaseactivity',s("Catalysis","of","the","reaction",":","2",",","3-bis","(","3-hydroxytetradecanoyl",")","-beta-D-glucosaminyl","1-phosphate","+","UDP-2",",","3-bis","(","3-hydroxytetradecanoyl",")","-D-glucosamine","=","2",",","3-bis","(","3-hydroxytetradecanoyl",")","-D-glucosaminyl-","(","1-","&","gt",";","6",")","-beta-D-2",",","3-bis","(","3-hydroxytetradecanoyl",")","-beta-D-glucosaminyl","1-phosphate","+","H","(","+",")","+","UDP","."),4248449). assertion_content_comment('oboGo_LipidBinding_5',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4230325). assertion_content_comment('oboGo_LipidLinkedpeptidoglycantransporteractivity',s("Enables","the","directed","movement","of","lipid-linked","peptidoglycans","into",",","out","of","or","within","a","cell",",","or","between","cells","."),4290517). assertion_content_comment('oboGo_LipidLinkedpeptidoglycantransport',s("The","directed","movement","of","lipid-linked","peptidoglycans","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4294096). assertion_content_comment('oboGo_LipidPhosphatephosphataseactivity',s("Catalysis","of","the","reaction",":","(","9S",",","10S",")","-10-hydroxy-9-","(","phosphonooxy",")","octadecanoate","+","H","(","2",")","O","=","(","9S",",","10S",")","-9",",","10-dihydroxyoctadecanoate","+","phosphate","."),4343478). assertion_content_comment('oboGo_LipidTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","lipid","(","in",")","=","ADP","+","phosphate","+","lipid","(","out",")"),4360920). assertion_content_comment('oboGo_LipoateProteinligaseactivity',s("Catalysis","of","the","formation","of","carbon-nitrogen","bonds","between","lipoate","(","5-","(","1",",","2-dithiolan-3-yl",")","pentanoate",")","and","a","protein","."),4302328). assertion_content_comment('oboGo_Lipopolysaccharide_15_GalactosyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","lipopolysaccharide","=","UDP","+","1",",","5","alpha-D-galactosyl-lipopolysaccharide","."),4376866). assertion_content_comment('oboGo_Lipopolysaccharide_16_GalactosyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","lipopolysaccharide","=","UDP","+","1",",","6","alpha-D-galactosyl-lipopolysaccharide","."),4248568). assertion_content_comment('oboGo_Lipopolysaccharide3AlphaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","lipopolysaccharide","=","UDP","+","1",",","3","alpha-D-galactosyl-lipopolysaccharide","."),4248669). assertion_content_comment('oboGo_LipopolysaccharideMediatedsignalingpathway',s("The","series","of","molecular","signals","generated","in","response","to","detection","of","lipopolysaccharide",".","Lipopolysaccharides","(","LPS",")","are","major","components","of","the","outer","membrane","of","Gram-negative","bacteria",",","making","them","prime","targets","for","recognition","by","the","immune","system","."),4056742). assertion_content_comment('oboGo_LipopolysaccharideNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","lipopolysaccharide","=","UDP","+","N-acetyl-D-glucosaminyl-lipopolysaccharide","."),4248689). assertion_content_comment('oboGo_LipopolysaccharideNAcetylmannosaminouronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","lipopolysaccharide","+","UDP-N-acetylmannosaminouronate","=","N-acetyl-beta-D-mannosaminouronosyl-1",",","4-lipopolysaccharide","+","UDP","."),4366833). assertion_content_comment('oboGo_LipopolysaccharideTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","lipopolysaccharide","(","in",")","=","ADP","+","phosphate","+","lipopolysaccharide","(","out",")"),4291929). assertion_content_comment('oboGo_LIsoleucinetransaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutaric","acid","+","L-isoleucine","=","(","S",")","-3-methyl-2-oxopentanoic","acid","+","L-glutamic","acid","."),4191854). assertion_content_comment('oboGo_LIsoleucinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-isoleucine","from","one","side","of","a","membrane","to","the","other",".","L-isoleucine","is","(","2R","*",",","3R","*",")","-2-amino-3-methylpentanoic","acid","."),4289707). assertion_content_comment('oboGo_Lithocholate6betaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","H","(","+",")","+","lithocholate","+","NADPH","+","O","(","2",")","=","6-beta-hydroxylithocholate","+","H","(","2",")","O","+","NADP","(","+",")"),4342041). assertion_content_comment('oboGo_LLactatebiosyntheticprocessfrompyruvate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L","(","+",")","lactate","from","other","compounds",",","including","pyruvate","."),4238425). assertion_content_comment('oboGo_LLactatedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-lactate","+","NAD","+","=","pyruvate","+","NADH","+","H","+"),4206938). assertion_content_comment('oboGo_LLactatedehydrogenasecytochromeactivity',s("Catalysis","of","the","reaction",":","(","S",")","-lactate","+","2","ferricytochrome","c","=","pyruvate","+","2","ferrocytochrome","c","."),4205750). assertion_content_comment('oboGo_LLDiaminopimelateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","LL-2",",","6-diaminopimelate","=","(","S",")","-2",",","3",",","4",",","5-tetrahydrodipicolinate","+","L-glutamate","+","H","(","2",")","O","+","H","(","+",")"),4335198). assertion_content_comment('oboGo_LLeucine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-leucine","+","2-oxoglutarate","=","4-methyl-2-oxopentanoate","+","L-glutamate","."),4270170). assertion_content_comment('oboGo_LLeucinetransaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutaratic","acid","+","L-leucine","=","4-methyl-2-oxopentanoate","+","L-glutamatic","acid","."),4191874). assertion_content_comment('oboGo_LLeucinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-leucine","from","one","side","of","a","membrane","to","the","other",".","L-leucine","is","2-amino-4-methylpentanoic","acid","."),4289722). assertion_content_comment('oboGo_LLysine6Monooxygenasenadphactivity',s("Catalysis","of","the","reaction",":","L-lysine","+","NADPH","+","O","(","2",")","=","N","(","6",")","-hydroxy-L-lysine","+","H","(","2",")","O","+","NADP","(","+",")"),4364574). assertion_content_comment('oboGo_LLysine6Oxidaseactivity',s("Catalysis","of","the","reaction",":","L-lysine","+","H","(","2",")","O","+","O","(","2",")","=","allysine","+","H","(","2",")","O","(","2",")","+","NH","(","4",")","(","+",")"),4342460). assertion_content_comment('oboGo_LLysine6Transaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","L-lysine","=","L-glutamate","+","allysine","."),4299808). assertion_content_comment('oboGo_LLysinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine",",","the","L-enantiomer","of","(","S",")","-2",",","6-diaminohexanoic","acid","."),4241343). assertion_content_comment('oboGo_LLysinecatabolicprocesstoacetate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","acetate","."),4241383). assertion_content_comment('oboGo_LLysinecatabolicprocesstoacetylCoa',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","acetyl-CoA","."),4241357). assertion_content_comment('oboGo_LLysinecatabolicprocesstoacetylCoavia5Aminopentanamide',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","acetyl-CoA",",","via","the","intermediate","5-aminopentanamide","."),4340718). assertion_content_comment('oboGo_LLysinecatabolicprocesstoacetylCoavialPipecolate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","acetyl-CoA",",","via","the","intermediate","L-pipecolate","."),4340706). assertion_content_comment('oboGo_LLysinecatabolicprocesstoacetylCoaviasaccharopine',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","acetyl-CoA",",","via","the","intermediate","saccharopine","."),4340602). assertion_content_comment('oboGo_LLysinecatabolicprocesstoglutaratebyacetylation',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","glutarate",",","by","acetylation","."),4241413). assertion_content_comment('oboGo_LLysinecatabolicprocessusinglysine6Aminotransferase',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-lysine","into","other","compounds",",","including","alpha-aminoadipate",";","in","this","pathway",",","L-lysine","is","converted","to","2-aminoadipate-6-semialdehyde","by","lysine","6-aminotransferase","."),4340744). assertion_content_comment('oboGo_LLysineeffluxtransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-lysine","from","the","inside","of","the","cell","to","the","outside","of","the","cell","across","a","membrane","."),4290342). assertion_content_comment('oboGo_LLysineLactamaseactivity',s("Catalysis","of","the","reaction",":","L-2-aminohexano-6-lactam","+","H","(","2",")","O","=","L-lysine","."),4269861). assertion_content_comment('oboGo_LLysinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-lysine",",","the","L-enantiomer","of","(","S",")","-2",",","6-diaminohexanoic","acid",",","i.e",".","(","2S",")","-2",",","6-diaminohexanoic","acid","."),4241340). assertion_content_comment('oboGo_LLysineoxidaseactivity',s("Catalysis","of","the","reaction",":","L-lysine","+","H","(","2",")","O","+","O","(","2",")","=","6-amino-2-oxohexanoate","+","H","(","2",")","O","(","2",")","+","NH","(","4",")","(","+",")"),4269849). assertion_content_comment('oboGo_LLysinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-lysine","from","one","side","of","a","membrane","to","the","other",".","L-lysine","is","2",",","6-diaminohexanoic","acid","."),4215926). assertion_content_comment('oboGo_LLyxosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-lyxose",",","the","L-enantiomer","of","aldopentose","lyxo-pentose",",","the","C-2","epimer","of","xylose","."),4240083). assertion_content_comment('oboGo_LMalatedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-malate","+","NAD","+","=","oxaloacetate","+","NADH","+","H","+"),4306636). assertion_content_comment('oboGo_LMethionine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","+","2-oxoglutarate","=","4-methylthio-2-oxobutyrate","+","L-glutamate","."),4182852). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessdirectfromoAcetylLHomoserine',s("The","direct","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","O-acetyl-L-homoserine","."),4238885). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromhomoserineviaoAcetylLHomoserineandcystathionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","methionine","from","other","compounds",",","including","homoserine",",","via","the","intermediates","O-acetyl-L-homoserine","and","cystathionine","."),4238913). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromhomoserineviaoPhosphoLHomoserineandcystathionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","homoserine",",","via","the","intermediates","O-phospho-L-homoserine","and","cystathionine","."),4340730). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromhomoserineviaoSuccinylLHomoserineandcystathionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","homoserine",",","via","the","intermediates","O-succinyl-L-homoserine","and","cystathionine","."),4238899). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromlHomoserineviacystathionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","L-homoserine",",","via","the","intermediate","cystathionine","."),4238842). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromoPhosphoLHomoserineandcystathionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","O-phospho-L-homoserine","and","cystathionine","."),4238871). assertion_content_comment('oboGo_LMethioninebiosyntheticprocessfromsAdenosylmethionine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine","from","other","compounds",",","including","S-adenosylmethionine","."),4045997). assertion_content_comment('oboGo_LMethioninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methionine",",","the","L-enantiomer","of","(","2S",")","-2-amino-4-","(","methylsulfanyl",")","butanoic","acid","."),4045988). assertion_content_comment('oboGo_LMethionineRSOxidereductaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","+","thioredoxin","disulfide","+","H2O","=","L-methionine","(","R",")","-S-oxide","+","thioredoxin","."),4342763). assertion_content_comment('oboGo_LMethioninesalvagefrommethylthioadenosine',s("The","generation","of","L-methionine","(","2-amino-4-","(","methylthio",")","butanoic","acid",")","from","methylthioadenosine","."),4242576). assertion_content_comment('oboGo_LMethioninesalvage',s("Any","process","that","generates","L-methionine","from","derivatives","of","it",",","without","de","novo","synthesis","."),4045994). assertion_content_comment('oboGo_LMethioninesecondaryactivetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-methionine","from","one","side","of","a","membrane","to","the","other",",","up","its","concentration","gradient",".","The","transporter","binds","the","solute","and","undergoes","a","series","of","conformational","changes",".","Transport","works","equally","well","in","either","direction","and","is","driven","by","a","chemiosmotic","source","of","energy",".","Chemiosmotic","sources","of","energy","include","uniport",",","symport","or","antiport","."),4345903). assertion_content_comment('oboGo_LMethionineSSOxidereductaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","+","thioredoxin","disulfide","+","H2O","=","L-methionine","(","S",")","-S-oxide","+","thioredoxin","."),4342746). assertion_content_comment('oboGo_LMethioninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-methionine","from","one","side","of","a","membrane","to","the","other",".","L-methionine","is","2-amino-4-","(","methylthio",")","butanoic","acid","."),4295663). assertion_content_comment('oboGo_LMethylmalonylCoabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-methylmalonyl-CoA",",","the","L-enantiomer","of","2-carboxypropanoyl-CoA","."),4244717). assertion_content_comment('oboGo_LMethylmalonylCoametabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-methylmalonyl-CoA",",","the","L-enantiomer","of","2-carboxypropanoyl-CoA",".","S-methylmalonyl-CoA","is","an","intermediate","in","the","beta","oxidation","of","odd-numbered","fatty","acids","in","animals","."),4244714). assertion_content_comment('oboGo_LMimosinesynthaseactivity',s("Catalysis","of","the","reaction",":","3",",","4-dihydroxypyridine","+","O-acetyl-L-serine","=","3-","(","3",",","4-dihydroxypyridinium-1-yl",")","-L-alanine","+","acetate","."),4265980). assertion_content_comment('oboGo_LoganateOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","loganate","=","S-adenosyl-L-homocysteine","+","loganin","."),4308693). assertion_content_comment('oboGo_Long_Chain_3_Hydroxyacyl_CoADehydrogenaseActivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-hydroxyacyl-CoA","+","NAD","(","P",")","+","=","3-oxoacyl-CoA","+","NAD","(","P",")","H","+","H","+",",","where","the","acyl","group","is","a","long-chain","fatty","acid","residue",".","Long-chain","fatty","acids","have","a","chain","length","of","between","12","and","18","carbons","."),4305421). assertion_content_comment('oboGo_LongChainAcylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","ETF","=","2",",","3-dehydroacyl-CoA","+","reduced","ETF","."),4205696). assertion_content_comment('oboGo_LongChainAlcoholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","a","long-chain","alcohol","+","2","NAD","+","+","H2O","=","a","long-chain","carboxylate","+","2","NADH","."),4270852). assertion_content_comment('oboGo_LongChainAlcoholoFattyAcyltransferaseactivity',s("Catalysis","of","the","reaction",":","a","long-chain-alcohol","+","acyl-CoA","=","a","long-chain","ester","+","CoA","."),4366121). assertion_content_comment('oboGo_LongChainAlcoholoxidaseactivity',s("Catalysis","of","the","reaction",":","2","long-chain","alcohol","+","O2","=","2","long-chain","aldehyde","+","2","H2O","."),4358879). assertion_content_comment('oboGo_LongChainAldehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","a","long-chain","aldehyde","+","NAD","+","=","a","long-chain","carboxylate","+","NADH","+","H","+"),4270839). assertion_content_comment('oboGo_LongChainEnoylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","(","3S",")","-3-hydroxyacyl-CoA","=","trans-2-enoyl-CoA","+","H2O","."),4305408). assertion_content_comment('oboGo_LongChainfattyacidacylCarrierProteinligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","an","acid","+","[","acyl-carrier","protein","]","=","AMP","+","diphosphate","+","acyl-","[","acyl-carrier","protein","]"),4248581). assertion_content_comment('oboGo_LongChainfattyacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","long-chain","fatty","acids",",","aliphatic","compounds","having","a","terminal","carboxyl","group","and","with","a","chain","length","of","C12-18","."),4317196). assertion_content_comment('oboGo_LongChainfattyacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","long-chain","fatty","acids",",","aliphatic","compounds","having","a","terminal","carboxyl","group","and","with","a","chain","length","of","C12-18","."),4317220). assertion_content_comment('oboGo_LongChainfattyacidCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","long-chain","carboxylic","acid","+","CoA","=","AMP","+","diphosphate","+","an","acyl-CoA",";","long-chain","fatty","acids","have","chain","lengths","of","C12-18","."),4205659). assertion_content_comment('oboGo_LongChainfattyacidluciferincomponentligaseactivity',s("Catalysis","of","the","reaction",":","protein","+","an","acid","+","ATP","=","an","acyl-protein","thiolester","+","diphosphate","+","AMP","."),4369672). assertion_content_comment('oboGo_LongChainfattyacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","long-chain","fatty","acids",",","aliphatic","compounds","having","a","terminal","carboxyl","group","and","with","a","chain","length","of","C12-18","."),4317192). assertion_content_comment('oboGo_LongChainfattyacidtransporteractivity',s("Enables","the","directed","movement","of","long-chain","fatty","acids","into",",","out","of","or","within","a","cell",",","or","between","cells",".","Long-chain","fatty","acids","have","a","chain","length","of","greater","than","12","carbons","."),4216147). assertion_content_comment('oboGo_LongChainfattyacidtransportingporinactivity',s("Catalysis","of","the","transfer","of","long-chain","fatty","acids","from","one","side","of","the","membrane","to","the","other",".","Long-chain","fatty","acids","have","a","chain","length","of","greater","than","12","carbons",".","This","transporter","is","a","porin","and","so","enables","the","energy","independent","passage","of","substances",",","sized","less","than","1000","Da",",","across","a","membrane",".","The","transmembrane","portions","of","porins","consist","exclusively","of","beta-strands","which","form","a","beta-barrel",".","They","are","found","in","the","outer","membranes","of","Gram-negative","bacteria",",","mitochondria",",","plastids","and","possibly","acid-fast","Gram-positive","bacteria","."),4292558). assertion_content_comment('oboGo_LongChainfattyacidtransport',s("The","directed","movement","of","long-chain","fatty","acids","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","A","long-chain","fatty","acid","is","an","aliphatic","compound","with","a","terminal","carboxyl","group","and","with","a","chain","length","greater","than","C12","."),4024593). assertion_content_comment('oboGo_LongChainfattyAcylCoabiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","a","long-chain","fatty-acyl-CoA","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","a","thioester","linkage","with","a","long-chain","fatty-acyl","group",".","Long-chain","fatty-acyl-CoAs","have","chain","lengths","ranging","from","C12-18","."),4382838). assertion_content_comment('oboGo_LongChainfattyAcylCoametabolicprocess',s("The","chemical","reactions","and","pathways","involving","long-chain","fatty-acyl-CoAs",",","any","derivative","of","coenzyme","A","in","which","the","sulfhydryl","group","is","in","a","thioester","linkage","with","a","long-chain","fatty-acyl","group",".","Long-chain","fatty-acyl-CoAs","have","chain","lengths","ranging","from","C12-18","."),4382833). assertion_content_comment('oboGo_LongChainFattyAcylCoareductaseactivity',s("Catalysis","of","the","reaction",":","a","long-chain","aldehyde","+","CoA","+","NADP","+","=","a","long-chain","acyl-CoA","+","NADPH","."),4270826). assertion_content_comment('oboGo_LongChainfattyAcylGlutamatedeacylaseactivity',s("Catalysis","of","the","reaction",":","N-long-chain-fatty-acyl-L-glutamate","+","H2O","=","a","fatty","acid","anion","+","L-glutamate","."),4253459). assertion_content_comment('oboGo_LongDayphotoperiodismflowering',s("A","change","from","the","vegetative","to","the","reproductive","phase","as","a","result","of","detection","of",",","or","exposure","to",",","a","period","of","light","that","exceeds","the","critical","day","length",".","The","critical","day","length","varies","between","species",".","Although","the","term","is","long-day","is","used",",","most","species","actually","respond","to","the","duration","of","the","night",",","so","that","the","response","will","occur","when","a","period","of","darkness","falls","short","of","the","number","of","hours","defined","by","24","minus","the","critical","day","length","."),4106337). assertion_content_comment('oboGo_LongDayphotoperiodism',s("A","change","in","state","or","activity","of","the","organism","(","in","terms","of","movement",",","secretion",",","enzyme","production",",","gene","expression",",","etc.",")","as","a","result","of","detection","of",",","or","exposure","to",",","a","day","length","that","exceeds","a","particular","duration","known","as","the","'","critical","day","length","'","The","critical","day","length","varies","between","species",".","Although","the","term","long-day","is","used",",","most","species","actually","respond","to","the","duration","of","the","night",",","so","that","the","response","will","occur","when","a","period","of","darkness","falls","short","of","the","number","of","hours","defined","by","24","hours","minus","the","critical","day","length","."),4106330). assertion_content_comment('oboGo_LongDistanceposttranscriptionalgenesilencing',s("A","posttranscriptional","gene","silencing","process","in","which","the","silencing","signal","originates","in","a","tissue","separate","from","the","tissue","in","which","the","silencing","takes","place","."),4332802). assertion_content_comment('oboGo_LongTermmaintenanceofgeneactivation',s("Any","mechanism",",","at","the","level","of","transcription","or","post-transcription",",","maintaining","gene","activation","in","the","long-term","."),4384656). assertion_content_comment('oboGo_LongTermmemory',s("The","memory","process","that","deals","with","the","storage",",","retrieval","and","modification","of","information","a","long","time","(","typically","weeks",",","months","or","years",")","after","receiving","that","information",".","This","type","of","memory","is","typically","dependent","on","gene","transcription","regulated","by","second","messenger","activation","."),4234925). assertion_content_comment('oboGo_LongTermstrengtheningofneuromuscularjunction',s("Any","process","that","results","in","an","increase","in","the","efficacy","of","transmission","at","a","neuromuscular","synapse","."),4081614). assertion_content_comment('oboGo_LongTermsynapticpotentiation',s("A","process","that","modulates","synaptic","plasticity","such","that","synapses","are","changed","resulting","in","the","increase","in","the","rate",",","or","frequency","of","synaptic","transmission","at","the","synapse","."),4159999). assertion_content_comment('oboGo_LongWaveSensitiveopsin',s("OBSOLETE",".","An","opsin","with","maximal","absorption","above","500","nm","."),4297107). assertion_content_comment('oboGo_LOrnithinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-ornithine","from","one","side","of","a","membrane","to","the","other",".","L-ornithine","is","2",",","5-diaminopentanoic","acid","."),4292230). assertion_content_comment('oboGo_LowAffinityglucose_Sodiumsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glucose","(","out",")","+","Na","+","(","out",")","=","glucose","(","in",")","+","Na","+","(","in",")","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","present","at","very","high","concentrations","."),4216619). assertion_content_comment('oboGo_LowAffinityhexosetransport',s("The","directed",",","low-affinity","movement","of","a","hexose","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","only","present","at","very","low","concentrations","."),4253299). assertion_content_comment('oboGo_LowAffinityhydrogen_Glucosesymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","glucose","+","H","+","=","glucose","+","H","+","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","present","at","very","high","concentrations",".","Symporter","activity","enables","the","active","transport","of","a","solute","across","a","membrane","by","a","mechanism","whereby","two","or","more","species","are","transported","together","in","the","same","direction","in","a","tightly","coupled","process","not","directly","linked","to","a","form","of","energy","other","than","chemiosmotic","energy","."),4216463). assertion_content_comment('oboGo_LowAffinityironiontransport',s("The","directed",",","low-affinity","movement","of","iron","(","Fe",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","only","present","at","very","low","concentrations","."),4345603). assertion_content_comment('oboGo_LowAffinitytryptophantransmembranetransporteractivity',s("Catalysis","of","the","low-affinity","transfer","of","L-tryptophan","from","one","side","of","a","membrane","to","the","other",".","Tryptophan","is","2-amino-3-","(","1H-indol-3-yl",")","propanoic","acid","."),4333365). assertion_content_comment('oboGo_LowAffinityzinciontransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","Zn2","+","=","Zn2","+",",","probably","powered","by","proton","motive","force",".","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","present","at","very","high","concentrations","."),4345403). assertion_content_comment('oboGo_LowAffinityzinciontransport',s("The","directed",",","low-affinity","movement","of","zinc","(","Zn",")","ions","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","In","low","affinity","transport","the","transporter","is","able","to","bind","the","solute","only","if","it","is","only","present","at","very","low","concentrations","."),4228952). assertion_content_comment('oboGo_LowDensitylipoproteincatabolicprocess',s("OBSOLETE",".","The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","low-density","lipoproteins",",","also","known","as","beta","lipoproteins",",","one","of","the","classes","of","lipoproteins","found","in","the","bloodstream","of","animals",",","acting","as","a","carrier","for","cholesterol","and","fats","."),4300428). assertion_content_comment('oboGo_LowDensitylipoproteinparticlebinding',s("Interacting","selectively","and","non-covalently","with","a","low-density","lipoprotein","particle",",","a","lipoprotein","particle","that","is","rich","in","cholesterol","esters","and","low","in","triglycerides",",","is","typically","composed","of","APOB100","and","APOE",",","and","has","a","density","of","1.02-1.06","g/ml","and","a","diameter","of","between","20-25","nm","."),4215091). assertion_content_comment('oboGo_LowDensitylipoproteinparticleclearance',s("The","process","in","which","a","low-density","lipoprotein","particle","is","removed","from","the","blood","via","receptor-mediated","endocytosis","and","its","constituent","parts","degraded","."),4035876). assertion_content_comment('oboGo_LowDensitylipoproteinparticledisassemblyinvolvedincholesteroltransport',s("The","disassembly","into","constituent","parts","of","the","low-density","lipoprotein","particle","in","the","lysosome","that","contributes","to","cholesterol","transport","."),4149008). assertion_content_comment('oboGo_LowDensitylipoproteinparticlemediatedsignaling',s("A","series","of","molecular","signals","mediated","by","the","detection","of","low-density","lipoprotein","particle","."),4109401). assertion_content_comment('oboGo_LowDensitylipoproteinparticlereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","low-density","lipoprotein","receptor","."),4275884). assertion_content_comment('oboGo_LowDensitylipoproteinparticlereceptorbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","low-density","lipoprotein","receptors",",","cell","surface","proteins","that","mediate","the","endocytosis","of","low-density","lipoprotein","particles","by","cells","."),4091388). assertion_content_comment('oboGo_LowDensitylipoproteinparticlereceptorcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","low-density","lipoprotein","particle","receptor","molecule",",","a","macromolecule","that","undergoes","combination","with","a","hormone",",","neurotransmitter",",","drug","or","intracellular","messenger","to","initiate","a","change","in","cell","function","."),4070395). assertion_content_comment('oboGo_LowDensityLipoproteinparticlereceptorkinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","low-density","lipoprotein","L-serine","=","ADP","+","low-density","lipoprotein","O-phospho-L-serine","."),4270807). assertion_content_comment('oboGo_LowDensitylipoproteinparticleremodeling',s("The","acquisition",",","loss","or","modification","of","a","protein","or","lipid","within","a","low-density","lipoprotein","particle",",","including","the","hydrolysis","of","triglyceride","by","hepatic","lipase",",","with","the","subsequent","loss","of","free","fatty","acid",",","and","the","transfer","of","cholesterol","esters","from","LDL","to","a","triglyceride-rich","lipoprotein","particle","by","cholesteryl","ester","transfer","protein","(","CETP",")",",","with","the","simultaneous","transfer","of","triglyceride","to","LDL","."),4355605). assertion_content_comment('oboGo_LowDensitylipoproteinparticle',s("A","lipoprotein","particle",",","rich","in","cholesterol","esters","and","low","in","triglycerides","that","is","typically","composed","of","APOB100","and","APOE","and","has","a","density","of","1.02-1.06","g/ml","and","a","diameter","of","between","20-25","nm",".","LDL","particles","are","formed","from","VLDL","particles","(","via","IDL",")","by","the","loss","of","triglyceride","and","gain","of","cholesterol","ester",".","They","transport","endogenous","cholesterol","(","and","to","some","extent","triglycerides",")","from","peripheral","tissues","back","to","the","liver","."),4355890). assertion_content_comment('oboGo_LowDensitylipoproteinreceptoractivity',s("Combining","with","a","low-density","lipoprotein","particle","to","initiate","a","change","in","cell","activity","."),4215095). assertion_content_comment('oboGo_LowDensitylipoproteinreceptorparticlemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","low-density","lipoprotein","receptors","."),4070374). assertion_content_comment('oboGo_LowDensitylipoprotein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4216124). assertion_content_comment('oboGo_LowVoltageGatedcalciumchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","low","voltage-gated","channel",".","A","low","voltage-gated","channel","is","a","channel","whose","open","state","is","dependent","on","low","voltage","across","the","membrane","in","which","it","is","embedded","."),4255294). assertion_content_comment('oboGo_LPhenylalanine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-phenylalanine","+","2-oxoglutarate","=","phenylpyruvate","+","L-glutamate","."),4181657). assertion_content_comment('oboGo_LPhenylalanineaminotransferaseactivity',s("Catalysis","of","the","transfer","of","an","amino","group","from","L-phenylalanine","to","an","acceptor",",","usually","a","2-oxo","acid","."),4174581). assertion_content_comment('oboGo_LPhenylalaninebiosyntheticprocessfromchorismatevialArogenate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-phenylalanine","from","other","compounds",",","including","chorismate",",","via","the","intermediate","L-arogenate","."),4340460). assertion_content_comment('oboGo_LPhenylalaninebiosyntheticprocessfromchorismateviaphenylpyruvate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-phenylalanine","from","other","compounds",",","including","chorismate",",","via","the","intermediate","phenylpyruvate","."),4340501). assertion_content_comment('oboGo_LPhenylalaninebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-phenylalanine",",","the","L-enantiomer","of","2-amino-3-phenylpropanoic","acid",",","i.e",".","(","2S",")","-2-amino-3-phenylpropanoic","acid","."),4257155). assertion_content_comment('oboGo_LPhenylalaninecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","phenylalanine",",","2-amino-3-phenylpropanoic","acid","."),4231611). assertion_content_comment('oboGo_LPhenylalaninemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-phenylalanine",",","the","L-enantiomer","of","2-amino-3-phenylpropanoic","acid",",","i.e",".","(","2S",")","-2-amino-3-phenylpropanoic","acid","."),4231590). assertion_content_comment('oboGo_LPhenylalanine_Pyruvateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","pyruvate","+","L-phenylalanine","=","phenylpyruvate","+","L-alanine","."),4368851). assertion_content_comment('oboGo_LPhenylalaninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-phenylalanine","from","one","side","of","a","membrane","to","the","other",".","L-phenylalanine","is","2-amino-3-phenylpropanoic","acid","."),4292300). assertion_content_comment('oboGo_LPipecolatedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-pipecolate","+","acceptor","=","delta1-piperideine-6-carboxylate","+","reduced","acceptor",".","Delta1-piperideine-6-carboxylate","is","also","known","as","2",",","3",",","4",",","5-tetrahydropyridine-2-carboxylate","."),4269838). assertion_content_comment('oboGo_LPipecolateoxidaseactivity',s("Catalysis","of","the","reaction",":","L-pipecolate","+","O","(","2",")","=","2",",","3",",","4",",","5-tetrahydropyridine-2-carboxylate","+","H","(","2",")","O","(","2",")","+","H","(","+",")","Delta1-piperideine-6-carboxylate","is","also","known","as","2",",","3",",","4",",","5-tetrahydropyridine-2-carboxylate","."),4269816). assertion_content_comment('oboGo_LPPG_FO2PhosphoLLactatetransferaseactivity',s("Catalysis","of","the","reaction",":","7",",","8-didemethyl-8-hydroxy-5-deazariboflavin","+","lactyl-2-diphospho-5","'","-guanosine","=","coenzyme","F420-0","+","GMP","."),4326026). assertion_content_comment('oboGo_LProlinebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-proline",",","an","L-enantiomer","of","a","chiral",",","cyclic",",","nonessential","alpha-amino","acid","found","in","peptide","linkage","in","proteins","."),4222214). assertion_content_comment('oboGo_LProlinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-proline","from","one","side","of","a","membrane","to","the","other",".","L-proline","is","pyrrolidine-2-carboxylic","acid","."),4215864). assertion_content_comment('oboGo_LRhamnonatedehydrataseactivity',s("Catalysis","of","the","reaction",":","L-rhamnonate","=","2-dehydro-3-deoxy-L-rhamnonate","+","H","(","2",")","O","."),4269827). assertion_content_comment('oboGo_L_Rhamnono_14_LactonaseActivity',s("Catalysis","of","the","reaction",":","L-rhamnono-1",",","4-lactone","+","H","(","2",")","O","=","L-rhamnonate","+","H","(","+",")"),4269794). assertion_content_comment('oboGo_LRhamnose1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-rhamnofuranose","+","NAD","(","+",")","=","L-rhamnono-1",",","4-lactone","+","H","(","+",")","+","NADH","."),4269806). assertion_content_comment('oboGo_LRhamnoseisomeraseactivity',s("Catalysis","of","the","reaction",":","L-rhamnose","=","L-rhamnulose","."),4251438). assertion_content_comment('oboGo_L_Ribulose_5_Phosphate3_EpimeraseActivity',s("Catalysis","of","the","reaction",":","L-ribulose","5-phosphate","=","L-xylulose","5-phosphate","."),4360682). assertion_content_comment('oboGo_LRibulosePhosphate4Epimeraseactivity',s("Catalysis","of","the","reaction",":","L-ribulose","5-phosphate","=","D-xylulose","5-phosphate","."),4251421). assertion_content_comment('oboGo_LRRDomainMediatedcomplexassembly',s("A","process","of","protein","complex","assembly","in","which","the","arrangement","and","bonding","together","of","the","set","of","components","that","form","the","protein","complex","is","mediated","by","an","LRR","(","leucine-rich","repeat",")","domain","interaction","."),4171153). assertion_content_comment('oboGo_LSerineammoniaLyaseactivity',s("Catalysis","of","the","reaction",":","L-serine","=","pyruvate","+","NH3","."),4185844). assertion_content_comment('oboGo_LSerinebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-serine",",","the","L-enantiomer","of","serine",",","i.e",".","(","2S",")","-2-amino-3-hydroxypropanoic","acid","."),4232133). assertion_content_comment('oboGo_LSerinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-serine",",","the","L-enantiomer","of","serine",",","i.e",".","(","2S",")","-2-amino-3-hydroxypropanoic","acid","."),4232148). assertion_content_comment('oboGo_LSerinehydroLyaseaddingindolelTryptophanFormingactivity',s("Catalysis","of","the","reaction",":","indole","+","L-serine","=","L-tryptophan","+","H2O","."),4191428). assertion_content_comment('oboGo_LSerinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-serine",",","the","L-enantiomer","of","serine",",","i.e",".","(","2S",")","-2-amino-3-hydroxypropanoic","acid","."),4231827). assertion_content_comment('oboGo_LSerinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-serine","from","one","side","of","a","membrane","to","the","other",".","L-serine","is","the","L-enantiomer","of","2-amino-3-hydroxypropanoic","acid","."),4292621). assertion_content_comment('oboGo_LSerinetransport',s("The","directed","movement","of","L-serine",",","the","L-enantiomer","of","2-amino-3-hydroxypropanoic","acid",",","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4294068). assertion_content_comment('oboGo_LSerylTrnaseckinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-seryl-tRNA","(","Sec",")","=","ADP","+","O-phospho-L-seryl-tRNA","(","Sec",")"),4328596). assertion_content_comment('oboGo_LSerylTrnasecseleniumtransferaseactivity',s("Catalysis","of","the","reaction",":","L-seryl-tRNA","(","Sec",")","+","selenophosphate","=","L-selenocysteinyl-tRNA","(","Sec",")","+","H2O","+","phosphate","."),4211681). assertion_content_comment('oboGo_LsmContainingsmnSmproteincomplex',s("An","SMN-Sm","protein","complex","formed","by","the","association","of","the","methylated","Sm","proteins","B/B","'",",","D3",",","E",",","F",",","and","G",",","and","Lsm10","and","Lsm11",",","with","the","SMN","complex",".","This","complex","forms","Sm","cores","on","U7","snRNA","."),4349255). assertion_content_comment('oboGo_LSorbosebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","L-sorbose",",","the","L-enantiomer","of","the","ketohexose","xylo-2-hexulose",".","L-sorbose","is","formed","by","bacterial","oxidation","of","sorbitol","."),4315207). assertion_content_comment('oboGo_LSorbosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-sorbose",",","the","L-enantiomer","of","the","ketohexose","xylo-2-hexulose","."),4315121). assertion_content_comment('oboGo_LSorbosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","sorbose",",","the","L-enantiomer","of","the","ketohexose","xylo-2-hexulose",".","L-sorbose","is","formed","by","bacterial","oxidation","of","sorbitol","."),4240185). assertion_content_comment('oboGo_LSorboseoxidaseactivity',s("Catalysis","of","the","reaction",":","L-sorbose","+","O","(","2",")","=","5-dehydro-D-fructose","+","H","(","2",")","O","(","2",")"),4270307). assertion_content_comment('oboGo_LTartratedehydrataseactivity',s("Catalysis","of","the","reaction",":","L-tartrate","=","H","(","2",")","O","+","oxaloacetate","."),4252327). assertion_content_comment('oboGo_LThreonate3Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-threonate","+","NAD","(","+",")","=","3-dehydro-L-threonate","+","H","(","+",")","+","NADH","."),4270295). assertion_content_comment('oboGo_LThreonine3Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","L-threonine","+","NAD","(","+",")","=","aminoacetone","+","CO","(","2",")","+","NADH","."),4233463). assertion_content_comment('oboGo_LThreonineammoniaLyaseactivity',s("Catalysis","of","the","reaction",":","L-threonine","=","2-oxobutanoate","+","NH3","."),4202260). assertion_content_comment('oboGo_LThreoninetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-threonine","from","one","side","of","a","membrane","to","the","other",".","L-threonine","is","(","2R","*",",","3S","*",")","-2-amino-3-hydroxybutanoic","acid","."),4292638). assertion_content_comment('oboGo_LTryptophan_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-tryptophan","+","2-oxoglutarate","=","indolepyruvate","+","L-glutamate","."),4264621). assertion_content_comment('oboGo_LTryptophanaminotransferaseactivity',s("Catalysis","of","the","transfer","of","an","amino","group","from","L-tryptophan","to","an","acceptor",",","usually","a","2-oxo","acid","."),4174983). assertion_content_comment('oboGo_LTryptophan_Pyruvateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-tryptophan","+","pyruvate","=","indolepyruvate","+","L-alanine","."),4182500). assertion_content_comment('oboGo_LTryptophantransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-tryptophan","from","one","side","of","a","membrane","to","the","other",".","Tryptophan","is","2-amino-3-","(","1H-indol-3-yl",")","propanoic","acid","."),4216866). assertion_content_comment('oboGo_LTyrosine_2Oxoglutarateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-tyrosine","+","2-oxoglutarate","=","4-hydroxyphenylpyruvate","+","L-glutamate","."),4199614). assertion_content_comment('oboGo_LTyrosineaminotransferaseactivity',s("Catalysis","of","the","transfer","of","an","amino","group","from","L-tyrosine","to","an","acceptor",",","usually","a","2-oxo","acid","."),4174600). assertion_content_comment('oboGo_LTyrosine_Pyruvateaminotransferaseactivity',s("Catalysis","of","the","reaction",":","L-tyrosine","+","pyruvate","=","4-hydroxyphenylpyruvate","+","L-alanine","."),4182833). assertion_content_comment('oboGo_LTyrosinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-tyrosine","from","one","side","of","a","membrane","to","the","other",".","L-tyrosine","is","2-amino-3-","(","4-hydroxyphenyl",")","propanoic","acid","."),4216849). assertion_content_comment('oboGo_LungAssociatedmesenchymedevelopment',s("The","biological","process","whose","specific","outcome","is","the","progression","of","a","lung-associated","mesenchyme","from","an","initial","condition","to","its","mature","state",".","This","process","begins","with","the","formation","of","lung-associated","mesenchyme","and","ends","with","the","mature","structure",".","Lung-associated","mesenchyme","is","the","tissue","made","up","of","loosely","connected","mesenchymal","cells","in","the","lung","."),4117581). assertion_content_comment('oboGo_Luteolin_7_O_Diglucuronide4_O_GlucuronosyltransferaseActivity',s("Catalysis","of","the","reaction",":","luteolin","7-O-","[","(","beta-D-glucosiduronate",")","-","(","1-","&","gt",";","2",")","-","(","beta-D-glucosiduronate",")","]","+","UDP-alpha-D-glucuronate","=","H","(","+",")","+","luteolin","7-O-","[","(","beta-D-glucosiduronate",")","-","(","1-","&","gt",";","2",")","-","(","beta-D-glucosiduronate",")","]","4","'","-O-beta-D-glucosiduronate","+","UDP","."),4366803). assertion_content_comment('oboGo_Luteolin_7_O_Glucuronide7_O_GlucuronosyltransferaseActivity',s("Catalysis","of","the","reaction",":","luteolin","7-O-beta-D-glucosiduronate","+","UDP-alpha-D-glucuronate","=","H","(","+",")","+","luteolin","7-O-","[","(","beta-D-glucosiduronate",")","-","(","1-","&","gt",";","2",")","-","(","beta-D-glucosiduronate",")","]","+","UDP","."),4366818). assertion_content_comment('oboGo_Luteolin7OGlucuronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","luteolin","+","UDP-alpha-D-glucuronate","=","luteolin","7-O-beta-D-glucosiduronate","+","UDP","."),4270902). assertion_content_comment('oboGo_LuteolinOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","luteolin","=","4","'",",","5",",","7-trihydroxy-3","'","-methoxyflavone","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308759). assertion_content_comment('oboGo_LutropinChoriogonadotropichormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","lutropin-choriogonadotropic","hormone","receptor","."),4323002). assertion_content_comment('oboGo_LValinetransaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutaratic","acid","+","L-valine","=","3-methyl-2-oxobutanoic","acid","+","L-glutamatic","acid","."),4191864). assertion_content_comment('oboGo_LValinetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","L-valine","from","one","side","of","a","membrane","to","the","other",".","L-valine","is","2-amino-3-methylbutanoic","acid","."),4216811). assertion_content_comment('oboGo_LXylitolcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-xylitol",",","a","five-carbon","sugar","alcohol","derived","from","xylose","by","reduction","of","the","carbonyl","group","."),4244553). assertion_content_comment('oboGo_LXylitolcatabolicprocesstoxylulose5Phosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","L-xylitol","to","form","xylulose","5-phosphate",".","L-xylitol","is","converted","into","L-xylulose",",","which","is","then","phosphorylated","to","L-xylulose-5-phosphate",".","This","is","converted","to","D-xylulose-5-phosphate","via","the","intermediate","L-ribulose-5-phosphate","."),4244559). assertion_content_comment('oboGo_LXylitolmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","L-xylitol",",","a","five-carbon","sugar","alcohol","derived","from","xylose","by","reduction","of","the","carbonyl","group",".","It","is","as","sweet","as","sucrose","and","is","used","as","a","noncariogenic","sweetner","and","as","a","sugar","substitute","in","diabetic","diets","."),4244550). assertion_content_comment('oboGo_LXylose1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","aldehydo-L-xylose","+","NADP","(","+",")","=","L-xylono-1",",","4-lactone","+","H","(","+",")","+","NADPH","."),4270327). assertion_content_comment('oboGo_LXylulokinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-xylulose","=","ADP","+","L-xylulose","5-phosphate","."),4251387). assertion_content_comment('oboGo_LXylulosereductasenadactivity',s("Catalysis","of","the","reaction",":","xylitol","+","NAD","+","=","L-xylulose","+","NADH","+","H","+"),4288476). assertion_content_comment('oboGo_LXylulosereductasenadpactivity',s("Catalysis","of","the","reaction",":","NADP","(","+",")","+","xylitol","=","L-xylulose","+","H","(","+",")","+","NADPH","."),4270317). assertion_content_comment('oboGo_LymphGlandDevelopment_1',s("OBSOLETE",".","The","process","whose","specific","outcome","is","the","progression","of","the","lymph","gland","over","time",",","from","its","formation","to","the","mature","structure",".","The","lymph","gland","is","a","small","bean-shaped","organ","made","up","of","a","loose","meshwork","of","reticular","tissue","in","which","are","enmeshed","large","numbers","of","lymphocytes",",","macrophages","and","accessory","cells",".","Lymph","glands","are","located","along","the","lymphatic","system","."),4234488). assertion_content_comment('oboGo_Lysine23Aminomutaseactivity',s("Catalysis","of","the","reaction",":","L-lysine","=","(","3S",")","-3",",","6-diaminohexanoate","."),4270879). assertion_content_comment('oboGo_Lysine2Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","L-lysine","+","O","(","2",")","=","5-aminopentanamide","+","CO","(","2",")","+","H","(","2",")","O","."),4270864). assertion_content_comment('oboGo_Lysine6Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","NAD","+","+","L-lysine","=","NH3","+","NADH","+","allysine","."),4265694). assertion_content_comment('oboGo_LysineBiosyntheticProcessViaAlphaAminoadipateandn2AcetylAlphaAminoadipate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","lysine","via","the","intermediates","alpha-aminoadipic","acid","and","N2-acetyl-alpha-aminoadipate",".","This","pathway","of","prokaryotic","lysine","biosynthesis","via","alpha-aminoadipate","was","discovered","in","the","hyper-thermophilic","Gram-negative","eubacterium","Thermus","thermophilus",".","The","pathway","proceeds","as","follows",":","alpha-ketoglutarate","is","converted","to","homocitrate",",","which","is","metabolized","to","3-carboxyhex-2-enedioate","and","then","homoisocitrate",".","This","is","then","decarboxylated","to","form","alpha-ketoadipate",",","which","is","then","converted","to","alpha-aminoadipate",".","This","undergoes","acetylation",",","to","form","N2-acetyl-alpha-aminoadipate",",","and","is","then","phosphorylated","to","give","N2-acetyl-alpha-aminoadipyl-delta-phosphate",".","This","is","converted","to","N2-acetyl-alpha-aminoadipate","semialdehyde",",","which","is","then","converted","to","N2-acetyl-L-lysine",".","A","final","deacetylation","reaction","produces","L-lysine","."),4183681). assertion_content_comment('oboGo_LysineBiosyntheticProcessViaAlphaAminoadipateandsaccharopine',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","lysine","via","the","intermediates","alpha-aminoadipic","acid","and","saccharopine",".","This","pathway","is","used","by","yeast","and","fungi","to","synthesize","the","essential","amino","acid","L-lysine",",","and","pathway","intermediates","are","often","incorporated","into","secondary","metabolic","processes",".","The","pathway","proceeds","as","follows",":","alpha-ketoglutarate","is","converted","to","homocitrate",",","which","is","metabolized","to","3-carboxyhex-2-enedioate","and","then","homoisocitrate",".","This","is","then","decarboxylated","to","form","alpha-ketoadipate",",","which","is","then","converted","to","alpha-aminoadipate",".","This","is","then","reduced","to","form","alpha-aminoadipate","6-semialdehyde",",","which","is","metabolized","to","saccharopine","and","finally","L-lysine","."),4183692). assertion_content_comment('oboGo_LysineBiosyntheticProcessViaDiaminopimelateAndL_2_Acetamido_6_Oxoheptanedioate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","lysine",",","via","the","intermediates","diaminopimelate","and","L-2-acetamido-6-oxoheptanedioate",";","in","this","pathway","tetrahydrodipicolinate","is","converted","to","meso-diaminopimelate","in","four","enzymatic","steps","."),4338816). assertion_content_comment('oboGo_LysineBiosyntheticProcessViaDiaminopimelateAndN_Succinyl_2_Amino_6_Ketopimelate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","lysine",",","via","the","intermediates","diaminopimelate","and","N-succinyl-2-amino-6-ketopimelate",";","in","this","pathway","tetrahydrodipicolinate","is","converted","to","meso-diaminopimelate","in","four","enzymatic","steps","."),4338859). assertion_content_comment('oboGo_LysineBiosyntheticProcessViaDiaminopimelateDiaminopimelateAminotransferasepathway',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","lysine",",","via","the","intermediate","diaminopimelate",";","in","this","pathway","tetrahydrodipicolinate","is","converted","to","meso-diaminopimelate","in","two","enzymatic","steps","."),4338845). assertion_content_comment('oboGo_LysineNAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl","phosphate","+","L-lysine","=","phosphate","+","N6-acetyl-L-lysine","."),4205627). assertion_content_comment('oboGo_LysineNMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","from","S-adenosyl-L-methionine","to","the","epsilon-amino","group","of","a","lysine","residue","."),4283055). assertion_content_comment('oboGo_LysinePyruvate6Transaminaseactivity',s("Catalysis","of","the","reaction",":","L-lysine","+","pyruvate","=","L-alanine","+","L-allysine","."),4270889). assertion_content_comment('oboGo_LysineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-lysine","+","tRNA","(","Lys",")","=","AMP","+","diphosphate","+","L-lysyl-tRNA","(","Lys",")"),4199881). assertion_content_comment('oboGo_LysineTrnapylligaseactivity',s("Catalysis","of","the","reaction",":","tRNA","(","Pyl",")","+","L-lysine","+","ATP","=","L-lysyl-tRNA","(","Pyl",")","+","diphosphate","+","AMP","."),4268312). assertion_content_comment('oboGo_LysoOrnithinelipidacyltransferaseactivity',s("Catalysis","of","the","reaction",":","lyso-ornithine","lipid","+","acyl-","[","acyl-carrier","protein","]","=","ornithine","lipid","+","[","acyl-carrier","protein","]"),4327454). assertion_content_comment('oboGo_LysosomalCysteineTypeendopeptidase',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4209333). assertion_content_comment('oboGo_LysosomalMembraneHydrogenTransportingatpase',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4255928). assertion_content_comment('oboGo_LysosomalProtonTransportingvTypeatpasecomplex',s("A","proton-transporting","two-sector","ATPase","complex","found","in","the","lysosomal","membrane",",","where","it","acts","as","a","proton","pump","to","mediate","acidification","of","the","lysosomal","lumen","."),4098821). assertion_content_comment('oboGo_LysosomalProtonTransportingvTypeatpasev0domain',s("The","V0","domain","of","a","proton-transporting","V-type","ATPase","found","in","the","lysosomal","membrane","."),4098844). assertion_content_comment('oboGo_LysosomalProtonTransportingvTypeatpasev1domain',s("The","V1","domain","of","a","proton-transporting","V-type","ATPase","found","in","the","lysosomal","membrane","."),4098833). assertion_content_comment('oboGo_LYSP100Associatednucleardomain',s("A","nuclear","body","that","is","enriched","in","the","lymphoid","cell-specific","protein","LYSp100B",";","LANDs","are","globular",",","electron-dense","structures","and","are","morphologically","distinct","from","the","annular","structures","characteristic","of","PML","bodies","."),4305904). assertion_content_comment('oboGo_LysylTrnaaminoacylation',s("The","process","of","coupling","lysine","to","lysyl-tRNA",",","catalyzed","by","lysyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179486). assertion_content_comment('oboGo_MAaacomplex',s("Protease","complex","of","the","mitochondrial","inner","membrane","that","is","involved","in","mitochondrial","protein","turnover","and","in","processing","of","proteins","imported","into","mitochondria","."),4007632). assertion_content_comment('oboGo_MacrocinOMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","macrocin","=","S-adenosyl-L-homocysteine","+","H","(","+",")","+","tylosin","."),4308458). assertion_content_comment('oboGo_Macrolide2Kinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","oleandomycin","=","ADP","+","2","H","(","+",")","+","oleandomycin","2","'","-O-phosphate","."),4270977). assertion_content_comment('oboGo_MacrophageColonyStimulatingfactorreceptoractivity',s("Combining","with","macrophage","colony-stimulating","factor","to","initiate","a","change","in","cell","activity","."),4214043). assertion_content_comment('oboGo_MacrophageColonyStimulatingfactorreceptorbinding',s("Interacting","selectively","and","non-covalently","with","the","macrophage","colony-stimulating","factor","receptor","."),4217355). assertion_content_comment('oboGo_MacrophageInflammatoryProtein_1AlphaProduction',s("The","appearance","of","macrophage","inflammatory","protein","1","alpha","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4130083). assertion_content_comment('oboGo_MacrophageInflammatoryProtein_1GammaProduction',s("The","appearance","of","macrophage","inflammatory","protein-1","gamma","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4129952). assertion_content_comment('oboGo_MadMaxcomplex',s("A","transcriptional","repressor","complex","that","consists","of","a","heterodimer","of","the","bHLH-ZIP","proteins","Mad","and","Max","."),4175393). assertion_content_comment('oboGo_MadMaxMsin3acomplex',s("A","transcriptional","repressor","complex","that","contains","a","heterodimer","of","the","bHLH-ZIP","proteins","Mad","and","Max",",","plus","mSin3A",",","a","homolog","of","the","yeast","Sin3p","."),4175282). assertion_content_comment('oboGo_MadMaxMsin3bcomplex',s("A","transcriptional","repressor","complex","that","contains","a","heterodimer","of","the","bHLH-ZIP","proteins","Mad","and","Max",",","plus","mSin3B",",","a","homolog","of","the","yeast","Sin3p","."),4175384). assertion_content_comment('oboGo_MagnesiumDependentproteinserinethreoninephosphataseactivity',s("Catalysis","of","the","reactions",":","protein","serine","phosphate","+","H2O","=","protein","serine","+","phosphate",";","and","protein","threonine","phosphate","+","H2O","=","protein","threonine","+","phosphate",".","These","reactions","require","the","presence","of","magnesium","."),4201022). assertion_content_comment('oboGo_MagnesiumDependentproteinserinethreoninephosphatasecomplex',s("An","enzyme","complex","that","catalyzes","the","removal","of","serine-","or","threonine-bound","phosphate","groups","from","a","wide","range","of","phosphoproteins",",","including","a","number","of","enzymes","that","have","been","phosphorylated","under","the","action","of","a","kinase","."),4221029). assertion_content_comment('oboGo_MagnesiumImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Mg2","+","(","out",")","=","ADP","+","phosphate","+","Mg2","+","(","in",")"),4292105). assertion_content_comment('oboGo_MagnesiumProtoporphyrinixmonomethylesteroxidativecyclaseactivity',s("Catalysis","of","the","reaction",":","magnesium-protoporphyrin","IX","13-monomethyl","ester","+","3","NADPH","+","3","H","+","+","3","O2","=","divinylprotochlorophyllide","+","3","NADP","+","+","5","H2O","."),4331203). assertion_content_comment('oboGo_MaintenanceOfBloodBrainbarrier',s("Preserving","the","permeability","barrier","between","the","blood","and","the","brain","in","a","stable","functional","or","structural","state",".","The","cells","in","the","brain","are","packed","tightly","together","preventing","the","passage","of","most","molecules","from","the","blood","into","the","brain",".","Only","lipid","soluble","molecules","or","those","that","are","actively","transported","can","pass","through","the","blood-brain","barrier","."),4380035). assertion_content_comment('oboGo_MaintenanceOfChromatinSilencingAtSilentMatingTypecassette',s("The","maintenance","of","chromatin","in","a","transcriptionally","silent","state","such","as","heterochromatin","at","silent","mating-type","loci","."),4083243). assertion_content_comment('oboGo_MaintenanceOfFidelityInvolvedInDNADependentdnareplication',s("A","DNA","metabolic","process","that","prevents","or","corrects","errors","to","ensure","that","DNA","is","replicated","accurately",".","Errors","can","be","corrected","either","by","intrinsic","DNA","polymerase","proofreading","activity","or","via","mismatch","repair","."),4096639). assertion_content_comment('oboGo_MaintenanceOfImaginalDiscDerivedwinghairorientation',s("Ensuring","that","hairs","in","the","imaginal","disc-derived","wing","continue","to","point","distally","during","development",",","following","the","initial","establishment","of","wing","hair","polarity","."),4071296). assertion_content_comment('oboGo_MaintenanceOfImprintingAtMatingTypelocus',s("Any","process","involved","in","preserving","the","structure","of","a","stable","single-strand","DNA","lesion","that","triggers","programmed","gene","conversion","at","the","mating-type","locus",",","thereby","restricting","mating-type","interconversion","to","one","of","the","two","sister","chromatids","during","DNA","replication","."),4129535). assertion_content_comment('oboGo_MaintenanceOfSymbiontContainingvacuoleviasubstancesecretedbyhost',s("The","process","in","which","a","host","organism","maintains","the","structure","and","function","of","a","symbiont-containing","vacuole",",","mediated","by","a","substance","secreted","by","the","host",".","The","symbiont-containing","vacuole","is","a","membrane-bounded","vacuole","within","a","host","cell","in","which","a","symbiont","organism","resides","."),4080275). assertion_content_comment('oboGo_MalateAspartateshuttle',s("The","process","of","transferring","reducing","equivalents","from","the","cytosol","into","the","mitochondria",";","NADH","is","used","to","synthesise","malate","in","the","cytosol",";","this","compound","is","then","transported","into","the","mitochondria","where","it","is","converted","to","oxaloacetate","using","NADH",",","the","oxaloacetate","reacts","with","gluamate","to","form","aspartate",",","and","the","aspartate","then","returns","to","the","cytosol","to","complete","the","cycle","."),4096156). assertion_content_comment('oboGo_MalateCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","malate","+","CoA","=","ADP","+","phosphate","+","malyl-CoA","."),4270963). assertion_content_comment('oboGo_MalateDehydrogenaseOxaloacetateDecarboxylatingactivity',s("Catalysis","of","the","reaction",":","(","S",")","-malate","+","NAD","+","=","pyruvate","+","CO2","+","NADH","+","H","+","Also","decarboxylates","oxaloacetate","."),4305864). assertion_content_comment('oboGo_MalateDehydrogenaseOxaloacetateDecarboxylatingnadpactivity',s("Catalysis","of","the","reaction",":","(","S",")","-malate","+","NADP","+","=","pyruvate","+","CO2","+","NADPH","+","H","+","Also","decarboxylates","oxaloacetate","."),4205559). assertion_content_comment('oboGo_MaleCourtshipBehaviorProboscisMediatedlicking',s("The","process","during","courtship","where","the","male","fly","licks","the","genitalia","of","a","stationary","female","fly","with","his","proboscis",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4305279). assertion_content_comment('oboGo_MaleFemalegameterecognitionduringdoublefertilization',s("The","initial","contact","step","made","between","the","male","gamete","and","the","female","gamete","during","double","fertilization",".","An","example","can","be","found","in","Arabidopsis","thaliana","."),4147658). assertion_content_comment('oboGo_MaleGermLinecystencapsulation',s("Formation","of","a","single","follicular","epithelium","around","the","germ-line","derived","cells","of","a","cyst","formed","in","the","male","gonad","."),4103559). assertion_content_comment('oboGo_MaleGermLinecystformation',s("Formation","of","a","cluster","of","germ-line","cells",",","in","the","male","gonad","of","an","insect",",","derived","from","a","single","founder","cell","(","cystoblast",")"),4017053). assertion_content_comment('oboGo_MaleGermLinesexdetermination',s("The","determination","of","sex","and","sexual","phenotype","in","a","male","organism","'","s","germ","line","."),4237052). assertion_content_comment('oboGo_MaleGermLinestemcelldivision',s("The","self-renewing","division","of","a","germline","stem","cell","in","the","male","gonad",",","to","produce","a","daughter","stem","cell","and","a","daughter","germ","cell",",","which","will","divide","to","form","the","male","gametes","."),4104285). assertion_content_comment('oboGo_MaleSpecificantibacterialhumoralresponse',s("An","immune","response","against","bacteria",",","specific","to","males","and","mediated","through","a","body","fluid","."),4232497). assertion_content_comment('oboGo_MaleSpecificantibacterialpeptideactivity',s("OBSOLETE",".","Inhibits","the","growth","of",",","or","directly","kills",",","bacterial","cells",",","but","which","is","only","expressed","in","males","."),4192994). assertion_content_comment('oboGo_MaleSpecificdefenseresponsetobacterium',s("A","set","of","reactions",",","specific","to","males",",","that","are","triggered","in","response","to","the","presence","of","a","bacterium","that","act","to","protect","the","cell","or","organism","."),4192987). assertion_content_comment('oboGo_MalonateCoATransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","malonate","=","acetate","+","malonyl-CoA","."),4271011). assertion_content_comment('oboGo_MalonateSemialdehydedehydrogenaseacetylatingactivity',s("Catalysis","of","the","reaction",":","3-oxopropanoate","+","CoA","+","NADP","+","=","acetyl-CoA","+","CO2","+","NADPH","+","H","+"),4277539). assertion_content_comment('oboGo_MalonateSemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","3-oxopropanoate","+","NAD","(","P",")","+","+","H2O","=","malonate","+","NAD","(","P",")","H","+","H","+"),4342568). assertion_content_comment('oboGo_MalonylCoadecarboxylaseactivity',s("Catalysis","of","the","reaction",":","malonyl-CoA","=","acetyl-CoA","+","CO2","."),4270626). assertion_content_comment('oboGo_MaltooligosaccharideImportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","maltooligosaccharide","(","out",")","=","ADP","+","phosphate","+","maltooligosaccharide","(","in",")"),4289517). assertion_content_comment('oboGo_Maltose_6_PhosphateGlucosidaseActivity',s("Catalysis","of","the","reaction",":","H2O","+","maltose","6","'","-phosphate","=","D-glucose","+","D-glucose","6-phosphate","."),4270614). assertion_content_comment('oboGo_MaltoseAlphaDGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","maltose","=","trehalose","."),4369686). assertion_content_comment('oboGo_MaltoseAlphaGlucosidaseactivity',s("Catalysis","of","the","reaction",":","alpha-maltose","+","H2O","=","2","alpha-D-glucose","."),4334784). assertion_content_comment('oboGo_MaltoseOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","maltose","=","CoA","+","acetyl-maltose","."),4248630). assertion_content_comment('oboGo_MaltoseTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","maltose","(","out",")","=","ADP","+","phosphate","+","maltose","(","in",")"),4291584). assertion_content_comment('oboGo_MalylCoalyaseactivity',s("Catalysis","of","the","reaction",":","(","3S",")","-3-carboxy-3-hydroxypropanoyl-CoA","=","acetyl-CoA","+","glyoxylate","."),4270590). assertion_content_comment('oboGo_MAML2RbpJkappaIcn1complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch1","(","ICN1",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-2","(","MAML2",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4165101). assertion_content_comment('oboGo_MAML2RbpJkappaIcn2complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch2","(","ICN2",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-2","(","MAML2",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4165090). assertion_content_comment('oboGo_MAML2RbpJkappaIcn3complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch3","(","ICN3",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-2","(","MAML2",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164926). assertion_content_comment('oboGo_MAML2RbpJkappaIcn4complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch4","(","ICN4",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-2","(","MAML2",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164937). assertion_content_comment('oboGo_MAML3RbpJkappaIcn1complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch1","(","ICN1",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-3","(","MAML3",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164948). assertion_content_comment('oboGo_MAML3RbpJkappaIcn2complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch2","(","ICN2",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-3","(","MAML3",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164970). assertion_content_comment('oboGo_MAML3RbpJkappaIcn3complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch3","(","ICN3",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-3","(","MAML3",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164959). assertion_content_comment('oboGo_MAML3RbpJkappaIcn4complex',s("A","protein","complex","that","consists","of","the","intracellular","domain","of","Notch4","(","ICN4",")",",","the","DNA-binding","transcription","factor","RBP-Jkappa",",","and","the","transcriptional","coactivator","Mastermind-like-3","(","MAML3",")",";","the","complex","is","involved","in","transcriptional","activation","in","response","to","Notch-mediated","signaling","."),4164991). assertion_content_comment('oboGo_Mandelate4Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-mandelate","+","5",",","6",",","7",",","8-tetrahydrobiopterin","+","O","(","2",")","=","(","S",")","-4-hydroxymandelate","+","7",",","8-dihydrobiopterin","+","H","(","2",")","O",".","(","S",")","-2-hydroxy-2-phenylacetate","is","also","known","as","S-mandelate","."),4266304). assertion_content_comment('oboGo_ManganeseIncorporationIntoMetalloOxygencluster',s("The","incorporation","of","manganese","into","a","metallo-oxygen","cluster","."),4307599). assertion_content_comment('oboGo_ManganeseIncorporationIntoMetalloOxygenclusterviabisLAspartatotrisLGlutamatolHistidinocalciumtetramanganesetetroxide',s("The","incorporation","of","manganese","into","a","4Mn-Ca-4O","complex","by","bis-L-aspartato","tris-L-glutamato","L-histidino","calcium","tetramanganese","tetroxide","as","in","the","photosystem","II","catalytic","site","."),4307601). assertion_content_comment('oboGo_ManganeseTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Mn2","+","(","out",")","=","ADP","+","phosphate","+","Mn2","+","(","in",")"),4291447). assertion_content_comment('oboGo_Mannan12_13_Alpha_MannosidaseActivity',s("Catalysis","of","the","hydrolysis","of","1",",","2-","and","1",",","3-linkages","in","yeast","mannan",",","releasing","mannose","."),4344265). assertion_content_comment('oboGo_Mannan14Mannobiosidaseactivity',s("Catalysis","of","the","hydrolysis","of","1",",","4-beta-D-mannosidic","linkages","in","1",",","4-beta-D-mannans",",","to","remove","successive","mannobiose","residues","from","the","non-reducing","chain","ends","."),4344738). assertion_content_comment('oboGo_MannanEndo_14_Beta_MannosidaseActivity',s("Catalysis","of","the","random","hydrolysis","of","1",",","4-beta-D-mannosidic","linkages","in","mannans",",","galactomannans",",","glucomannans",",","and","galactoglucomannans","."),4302286). assertion_content_comment('oboGo_MannanEndo_16_Alpha_MannosidaseActivity',s("Catalysis","of","the","random","hydrolysis","of","1",",","6-alpha-D-mannosidic","linkages","in","unbranched","1",",","6-mannans","."),4254443). assertion_content_comment('oboGo_MannanExo_12_16_Alpha_MannosidaseActivity',s("Catalysis","of","the","hydrolysis","of","1",",","2-alpha-D-","and","1",",","6-alpha-D-","linkages","in","yeast","mannan",",","releasing","D-mannose","."),4344884). assertion_content_comment('oboGo_Mannitol_1_PhosphataseActivity',s("Catalysis","of","the","reaction",":","D-mannitol","1-phosphate","+","H","(","2",")","O","=","D-mannitol","+","2","H","(","+",")","+","phosphate","."),4270579). assertion_content_comment('oboGo_Mannitol_1_Phosphate5_DehydrogenaseActivity',s("Catalysis","of","the","reaction",":","D-mannitol","1-phosphate","+","NAD","+","=","D-fructose","6-phosphate","+","NADH","+","H","+"),4248642). assertion_content_comment('oboGo_Mannitol2Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","D-mannitol","+","NAD","+","=","D-fructose","+","NADH","."),4270557). assertion_content_comment('oboGo_Mannitol2Dehydrogenasenadpactivity',s("Catalysis","of","the","reaction",":","D-mannitol","+","NADP","(","+",")","=","D-fructose","+","H","(","+",")","+","NADPH","."),4270568). assertion_content_comment('oboGo_Mannose_1_PhosphateGuanylyltransferaseActivity',s("Catalysis","of","the","reaction",":","alpha-D-mannose","1-phosphate","+","GTP","=","diphosphate","+","GDP-alpha-D-mannose","."),4205588). assertion_content_comment('oboGo_Mannose_1_PhosphateGuanylyltransferaseGDPActivity',s("Catalysis","of","the","reaction",":","alpha-D-mannose","1-phosphate","+","GDP","+","H","(","+",")","=","GDP-alpha-D-mannose","+","phosphate","."),4248860). assertion_content_comment('oboGo_Mannose_6_Phosphate6_ReductaseActivity',s("Catalysis","of","the","reaction",":","D-mannitol","1-phosphate","+","NADP","(","+",")","=","D-mannose","6-phosphate","+","3","H","(","+",")","+","NADPH","."),4270529). assertion_content_comment('oboGo_Mannose_6_PhosphateIsomeraseActivity',s("Catalysis","of","the","reaction",":","D-mannose","6-phosphate","=","D-fructose","6-phosphate","."),4205470). assertion_content_comment('oboGo_MannoseEthanolaminephosphotransferaseactivity',s("Catalysis","of","the","transfer","of","ethanolamine","phosphate","to","a","mannose","residue","in","the","GPI","lipid","precursor","."),4285757). assertion_content_comment('oboGo_MannosePhosphateguanylyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","phosphate","group","from","GTP","or","GDP","to","a","mannose","molecule","."),4205586). assertion_content_comment('oboGo_Mannosyl_3_PhosphoglyceratePhosphataseActivity',s("Catalysis","of","the","reaction",":","2-","(","alpha-D-mannosyl",")","-3-phosphoglycerate","+","H","(","2",")","O","=","2-","(","alpha-D-mannosyl",")","-D-glycerate","+","phosphate","."),4268662). assertion_content_comment('oboGo_Mannosyl_3_PhosphoglycerateSynthaseActivity',s("Catalysis","of","the","reaction",":","3-phospho-D-glycerate","+","GDP-alpha-D-mannose","=","2-","(","alpha-D-mannosyl",")","-3-phosphoglycerate","+","GDP","+","H","(","+",")"),4269701). assertion_content_comment('oboGo_MannosylglycoproteinEndoBetaMannosidaseactivity',s("Catalysis","of","the","hydrolysis","of","the","alpha-D-mannosyl-","(","1-","&","gt",";","6",")","-beta-D-mannosyl-","(","1-","&","gt",";","4",")","-beta-D-N-acetylglucosaminyl-","(","1-","&","gt",";","4",")","-beta-D-N-acetylglucosaminyl","sequence","of","glycoprotein","to","alpha-D-mannosyl-","(","1-","&","gt",";","6",")","-D-mannose","and","beta-D-N-acetylglucosaminyl-","(","1-","&","gt",";","4",")","-beta-D-N-acetylglucosaminyl","sequences","."),4344355). assertion_content_comment('oboGo_MannosylGlycoproteinendoBetaNAcetylglucosaminidaseactivity',s("Catalysis","of","the","endohydrolysis","of","the","N",",","N","'","-diacetylchitobiosyl","unit","in","high-mannose","glycopeptides","and","glycoproteins","containing","the","-","[","Man","(","GlcNAc",")","2","]","Asn-structure",".","One","N-acetyl-D-glucosamine","residue","remains","attached","to","the","protein",";","the","rest","of","the","oligosaccharide","is","released","intact","."),4344665). assertion_content_comment('oboGo_MannosylInositolphosphorylceramidebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","mannosyl-inositol","phosphorylceramide",",","any","lipid","with","a","phosphodiester","bridge","between","an","inositol","residue","and","the","ceramide","group","which","contains","a","phosphoryl","(","-P","(","O",")","=",")","groups","and","a","mannose","derivative","."),4183648). assertion_content_comment('oboGo_MannosylInositolphosphorylceramidemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","mannosyl-inositol","phosphorylceramide",",","any","lipid","with","a","phosphodiester","bridge","between","an","inositol","residue","and","the","ceramide","group","which","contains","a","phosphoryl","(","-P","(","O",")","=",")","groups","and","a","mannose","derivative","."),4183638). assertion_content_comment('oboGo_MannosylOligosaccharide12AlphaMannosidaseactivity',s("Catalysis","of","the","hydrolysis","of","the","terminal","1",",","2-linked","alpha-D-mannose","residues","in","the","oligo-mannose","oligosaccharide","Man","(","9",")","(","GlcNAc",")","(","2",")"),4204459). assertion_content_comment('oboGo_Mannosyl_Oligosaccharide13_16_Alpha_MannosidaseActivity',s("Catalysis","of","the","hydrolysis","of","the","terminal","1",",","3-","and","1",",","6-linked","alpha-D-mannose","residues","in","the","mannosyl-oligosaccharide","Man","(","5",")","(","GlcNAc",")","(","3",")"),4204479). assertion_content_comment('oboGo_MannosylOligosaccharideglucosidaseactivity',s("Catalysis","of","the","exohydrolysis","of","the","non-reducing","terminal","glucose","residue","in","the","mannosyl-oligosaccharide","Glc","(","3",")","Man","(","9",")","GlcNAc","(","2",")"),4204405). assertion_content_comment('oboGo_MannosylOligosaccharidemannosidaseactivity',s("Catalysis","of","the","hydrolysis","of","the","terminal","alpha-D-mannose","residues","in","oligo-mannose","oligosaccharides","."),4204457). assertion_content_comment('oboGo_Mannotetraose2AlphaNAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","1",",","3-alpha-D-mannosyl-1",",","2-alpha-D-mannosyl-1",",","2-alpha-D-mannosyl-D-mannose","+","UDP-N-acetyl-D-glucosamine","=","1",",","3-alpha-D-mannosyl-1",",","2-","(","N-acetyl-alpha-D-glucosaminyl-alpha-D-mannosyl",")","-1",",","2-alpha-D-mannosyl-D-mannose","+","UDP","."),4366487). assertion_content_comment('oboGo_MAPKinaseanchoringactivity',s("OBSOLETE",".","Binds","to","MAP","kinase","and","anchors","it","to","a","particular","subcellular","location","."),4215474). assertion_content_comment('oboGo_MAPKinasescaffoldactivity',s("The","binding","activity","of","a","molecule","that","functions","as","a","physical","support","for","the","assembly","of","a","multiprotein","mitogen-activated","protein","kinase","(","MAPK",")","complex",".","Binds","multiple","kinases","of","the","MAPKKK","cascade",",","and","also","upstream","signaling","proteins",",","permitting","those","molecules","to","function","in","a","coordinated","way",".","Bringing","together","multiple","enzymes","and","their","substrates","enables","the","signal","to","be","transduced","quickly","and","efficiently","."),4215449). assertion_content_comment('oboGo_MAPKMediatedregulationofappressoriumformation',s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","symbiont","MAP","kinase-mediated","signal","transduction","during","appressorium","formation","on","or","near","its","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153862). assertion_content_comment('oboGo_MasculinizationOfHermaphroditicGermLine',s("The","determination","of","male","sex","and","sexual","phenotype","in","the","germ-line","of","the","hermaphrodite",".","An","example","of","this","is","found","in","Caenorhabditis","elegans","."),4306137). assertion_content_comment('oboGo_MATa1A1PreMrnasplicing',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4224291). assertion_content_comment('oboGo_MaternalDeterminationOfDorsalVentralAxisOvarianFollicularEpitheliumGermLineencoded',s("Polarization","of","the","ovarian","follicle","cells","along","the","dorsal-ventral","axis","by","a","gene","product","encoded","by","cells","of","the","germ","line","."),4247207). assertion_content_comment('oboGo_MaternalSpecificationOfDorsalVentralAxisOocyteGermLineencoded',s("Polarization","of","the","oocyte","along","the","dorsal-ventral","axis",",","by","a","gene","product","encoded","by","cells","of","the","germ","line",".","An","example","of","this","is","found","in","Drosophila","melanogaster","."),4235854). assertion_content_comment('oboGo_MatingTypeaFactorpheromonereceptoractivity',s("Combining","with","the","mating-type","a-factor","pheromone","to","initiate","a","change","in","cell","activity","."),4198522). assertion_content_comment('oboGo_MatingTypealphaFactorpheromonereceptoractivity',s("Combining","with","the","mating-type","alpha-factor","pheromone","to","initiate","a","change","in","cell","activity","."),4198535). assertion_content_comment('oboGo_MatingTypefactorpheromonereceptoractivity',s("Combining","with","a","mating-type","factor","pheromone","to","initiate","a","change","in","cell","activity","."),4198520). assertion_content_comment('oboGo_MatingTyperegionheterochromatin',s("Heterochromatic","regions","of","the","chromosome","found","at","silenced","mating-type","loci","."),4320344). assertion_content_comment('oboGo_Matrilysin_2Activity',s("OBSOLETE",".","Was","not","defined","before","being","made","obsolete","."),4310125). assertion_content_comment('oboGo_MaturationOf58SRRNAFromTetracistronicRRNATranscriptSSURrna58srrna2srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","5.8S","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","5.8S","rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","the","8.8S","rRNA",",","the","2S","rRNA",",","and","the","Large","Subunit","(","LSU",")","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976393). assertion_content_comment('oboGo_MaturationOf58SRRNAFromTricistronicRRNATranscriptSSURrna58srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","an","rRNA","molecule","originally","produced","as","part","of","a","tricistronic","rRNA","transcript","that","contained","the","Small","SubUnit","(","SSU",")","rRNA",",","the","5.8S","rRNA",",","and","the","Large","SubUnit","(","LSU",")","rRNA",",","in","that","order",",","from","5","'","to","3","'","along","the","primary","transcript","."),3976123). assertion_content_comment('oboGo_MaturationOf5SRRNAFromTetracistronicRRNATranscriptSSURrna58srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","5S","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","5S","rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),4362351). assertion_content_comment('oboGo_MaturationOfLSURrnafromtetracistronicrrnatranscriptssuRrna58srrna2srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Large","SubUnit","(","LSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","LSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","5.8","S","rRNA",",","2S","rRNA",",","and","Large","Subunit","(","LSU",")","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976404). assertion_content_comment('oboGo_MaturationOfLSURrnafromtetracistronicrrnatranscriptssuRrnalsuRrna45sRrna5sRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Large","SubUnit","(","LSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","LSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),4362324). assertion_content_comment('oboGo_MaturationOfLSURrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Large","SubUnit","(","LSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","LSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","5.8S","rRNA",",","and","Large","Subunit","(","LSU",")","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976072). assertion_content_comment('oboGo_MaturationOfLSURrnafromtricistronicrrnatranscriptssuRrnalsuRrna5s',s("Any","process","involved","in","the","maturation","of","a","precursor","Large","SubUnit","(","LSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","LSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976259). assertion_content_comment('oboGo_MaturationOfLSURrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Large","SubUnit","(","LSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","LSU-rRNA","molecule","."),3976042). assertion_content_comment('oboGo_MaturationOfSSURrnafromtetracistronicrrnatranscriptssuRrna58srrna2srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Small","SubUnit","(","SSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","SSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","5.8","S","rRNA",",","2S","rRNA",",","and","Large","Subunit","(","LSU",")","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976432). assertion_content_comment('oboGo_MaturationOfSSURrnafromtetracistronicrrnatranscriptssuRrnalsuRrna45sRrna5sRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Small","SubUnit","(","SSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","SSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tetracistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","4.5S","rRNA",",","and","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),4362333). assertion_content_comment('oboGo_MaturationOfSSURrnafromtricistronicrrnatranscriptssuRrna58srrnalsuRrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Small","SubUnit","(","SSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","SSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","5.8S","rRNA",",","and","the","Large","Subunit","(","LSU",")","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976238). assertion_content_comment('oboGo_MaturationOfSSURrnafromtricistronicrrnatranscriptssuRrnalsuRrna5s',s("Any","process","involved","in","the","maturation","of","a","precursor","Small","SubUnit","(","SSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","SSU-rRNA","molecule","from","the","pre-rRNA","molecule","originally","produced","as","a","tricistronic","rRNA","transcript","that","contains","the","Small","Subunit","(","SSU",")","rRNA",",","Large","Subunit","(","LSU",")","the","5S","rRNA","in","that","order","from","5","'","to","3","'","along","the","primary","transcript","."),3976287). assertion_content_comment('oboGo_MaturationOfSSURrna',s("Any","process","involved","in","the","maturation","of","a","precursor","Small","SubUnit","(","SSU",")","ribosomal","RNA","(","rRNA",")","molecule","into","a","mature","SSU-rRNA","molecule","."),3976234). assertion_content_comment('oboGo_MCresolbiosyntheticprocess',s("OBSOLETE",".","The","chemical","reactions","and","pathways","resulting","in","the","formation","of","m-cresol","(","3-hydroxytoluene",")",",","the","meta-isoform","of","cresol","."),4354381). assertion_content_comment('oboGo_MCresolcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","m-cresol","(","3-hydroxytoluene",")",",","the","meta-isoform","of","cresol","."),4314300). assertion_content_comment('oboGo_MCresolmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","m-cresol","(","3-hydroxytoluene",")",",","the","meta-isoform","of","cresol",".","Used","to","produce","agricultural","chemicals",",","and","in","specialty","resins",",","pharmaceuticals","and","pressure-sensitive","dyes","."),4272125). assertion_content_comment('oboGo_MechanicallyGatedionchannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","an","ion","by","a","channel","that","opens","in","response","to","a","mechanical","stress","."),4255585). assertion_content_comment('oboGo_MedialLayerOfCollagenAndCuticulinBasedcuticleextracellularmatrix',s("The","fluid-filled","cuticle","layer","that","lies","between","the","cortical","and","basal","layers","and","is","characterized","by","the","presence","of","regularly","spaced","columnar","struts","that","lie","on","either","side","of","the","annular","furrows","and","link","the","two","surrounding","layers",".","In","C",".","elegans",",","a","defined","medial","layer","is","found","only","in","adult","animals","."),4108901). assertion_content_comment('oboGo_MediumChainAcylCoadehydrogenaseactivity',s("Catalysis","of","the","reaction",":","acyl-CoA","+","acceptor","=","2",",","3-dehydroacyl-CoA","+","reduced","acceptor",",","where","the","acyl","group","is","a","medium-chain","fatty","acid","residue","."),4177852). assertion_content_comment('oboGo_MediumChainfattyacidbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","fatty","acids","with","a","chain","length","of","between","8","and","12","carbons","."),4281173). assertion_content_comment('oboGo_MediumChainfattyacidcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","fatty","acids","with","a","chain","length","of","between","8","and","12","carbons","."),4281189). assertion_content_comment('oboGo_MediumChainfattyacidCoaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","medium-chain","carboxylic","acid","+","CoA","=","AMP","+","diphosphate","+","an","acyl-CoA",";","medium-chain","fatty","acids","have","chain","lengths","of","C8-12","."),4320462). assertion_content_comment('oboGo_MediumChainfattyacidmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","medium-chain","fatty","acids",",","aliphatic","compounds","having","a","terminal","carboxyl","group","and","with","a","chain","length","of","C8-12","."),4281160). assertion_content_comment('oboGo_MediumChainfattyacidtransport',s("The","directed","movement","of","medium-chain","fatty","acids","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Medium-chain","fatty","acids","are","fatty","acids","with","a","chain","length","of","between","8","and","12","carbons","."),4361437). assertion_content_comment('oboGo_MediumTermmemory',s("The","memory","process","that","deals","with","the","storage",",","retrieval","and","modification","of","information","received","at","a","time","ago","that","is","intermediate","between","that","of","short","and","long","term","memory","(","30min","-","7hrs","in","Drosophila","melanogaster",")"),4159122). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakformationinvolvedinmeioticgeneconversion',s("The","cell","cycle","process","in","which","double-strand","breaks","are","generated","at","defined","hotspots","throughout","the","genome","during","meiosis","I","resulting","in","meiotic","gene","conversion",".","Meiotic","gene","conversion","is","the","cell","cycle","process","in","which","genetic","information","is","transferred","from","one","helix","to","another","."),4025237). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakformationinvolvedinreciprocalmeioticrecombination',s("The","cell","cycle","process","in","which","double-strand","breaks","are","generated","at","defined","hotspots","throughout","the","genome","during","meiosis","I","resulting","in","meiotic","recombination",".","Meiotic","recombination","is","the","cell","cycle","process","in","which","double","strand","breaks","are","formed","and","repaired","through","a","double","Holliday","junction","intermediate","."),4025185). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakformation',s("The","cell","cycle","process","in","which","double-strand","breaks","are","generated","at","defined","hotspots","throughout","the","genome","during","meiosis","I",".","This","results","in","the","initiation","of","meiotic","recombination","."),4025182). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakprocessinginvolvedinmeioticgeneconversion',s("The","cell","cycle","process","in","which","the","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","resulting","in","the","transfer","of","genetic","information","from","one","helix","to","another","."),4026822). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakprocessinginvolvedinreciprocalmeioticrecombination',s("The","cell","cycle","process","in","which","the","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","occurs","resulting","in","double","strand","break","formation","and","repair","through","a","double","Holliday","junction","intermediate","."),4026832). assertion_content_comment('oboGo_MeioticDNADoubleStrandbreakprocessing',s("The","cell","cycle","process","in","which","the","5","'","to","3","'","exonucleolytic","resection","of","the","DNA","at","the","site","of","the","break","to","form","a","3","'","single-strand","DNA","overhang","occurs",".","This","takes","place","during","meiosis","."),3977188). assertion_content_comment('oboGo_MelaninConcentratinghormoneactivity',s("The","action","characteristic","of","melanin-concentrating","hormone",",","a","cyclic","peptide","hormone","that",",","upon","receptor","binding",",","induces","melanin","aggregation","in","melanocytes",",","and","is","also","involved","in","regulating","food","intake","and","energy","balance","in","mammals","."),4309576). assertion_content_comment('oboGo_MelaninConcentratinghormonereceptoractivity',s("Combining","with","the","cyclic","peptide","hormone","melanin-concentrating","hormone","to","initiate","a","change","in","cell","activity","."),4311958). assertion_content_comment('oboGo_MelaninConcentratinghormonereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","melanin-concentrating","hormone","receptor","."),4322979). assertion_content_comment('oboGo_MelanocyteStimulatinghormoneactivity',s("The","action","characteristic","of","melanocyte-stimulating","hormone",",","any","of","three","peptide","hormones","that","are","produced","by","the","intermediate","lobe","of","the","pituitary","gland","and",",","upon","receptor","binding",",","cause","dispersal","of","melanosomes","in","melanophores","of","poikilothermic","vertebrates","."),4268258). assertion_content_comment('oboGo_MelanocyteStimulatinghormonereceptoractivity',s("Combining","with","melanocyte-stimulating","hormone","to","initiate","a","change","in","cell","activity","."),4198821). assertion_content_comment('oboGo_Melilotate3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","3-","(","2-hydroxyphenyl",")","propanoate","+","H","(","+",")","+","NADH","+","O","(","2",")","=","3-","(","2",",","3-dihydroxyphenyl",")","propanoate","+","H","(","2",")","O","+","NAD","(","+",")"),4270754). assertion_content_comment('oboGo_MembraneAssociatedguanylatekinase',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","GMP","=","ADP","+","GDP",",","associated","with","the","cell","membrane","."),4208254). assertion_content_comment('oboGo_MembraneAssociatedproteinwithguanylatekinaseactivityinteracting',s("OBSOLETE",".","The","interaction","with","synapse-associated","membrane-associated","protein","with","guanylate","kinase","activity","."),4258014). assertion_content_comment('oboGo_MembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","bounded","by","a","single","or","double","lipid","bilayer","membrane",".","Includes","the","nucleus",",","mitochondria",",","plastids",",","vacuoles",",","and","vesicles",".","Excludes","the","plasma","membrane","."),3971880). assertion_content_comment('oboGo_MembraneBoundedvesicle',s("Any","small",",","fluid-filled",",","spherical","organelle","enclosed","by","a","lipid","bilayer","."),3979444). assertion_content_comment('oboGo_MembraneEnclosedlumen',s("The","enclosed","volume","within","a","sealed","membrane","or","between","two","sealed","membranes",".","Encompasses","the","volume","enclosed","by","the","membranes","of","a","particular","organelle",",","e.g",".","endoplasmic","reticulum","lumen",",","or","the","space","between","the","two","lipid","bilayers","of","a","double","membrane","surrounding","an","organelle",",","e.g",".","nuclear","envelope","lumen","."),3972749). assertion_content_comment('oboGo_MembraneOligosaccharideglycerophosphotransferaseactivity',s("Catalysis","of","the","transfer","of","a","glycerophospho","group","from","one","membrane-derived","oligosaccharide","to","another","."),4369269). assertion_content_comment('oboGo_MenaquinoneDependentprotoporphyrinogenoxidaseactivity',s("Catalysis","of","the","reaction",":","protoporphyrinogen-IX","+","menaquinone","=","protoporphyrin-IX","+","reduced","menaquinone","."),4178975). assertion_content_comment('oboGo_Menth_2_EnoneHydrataseActivity',s("Catalysis","of","the","reaction",":","(","5R",")","-menth-2-enone","+","H2O","=","(","5R",")","-3-hydroxymenthone","."),4350665). assertion_content_comment('oboGo_Mentha_13_Dione_CoALigaseActivity',s("Catalysis","of","the","reaction",":","mentha-1",",","3-dione","+","CoASH","=","3",",","7-dimethyl-5-oxo-octyl-CoA","."),4350712). assertion_content_comment('oboGo_Menthofuransynthaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-pulegone","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","(","R",")","-menthofuran","+","2","H","(","2",")","O","+","NADP","(","+",")"),4186340). assertion_content_comment('oboGo_Mentholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","-",")","-menthol","+","NADP","(","+",")","=","(","2S",",","5R",")","-menthone","+","H","(","+",")","+","NADPH","."),4371718). assertion_content_comment('oboGo_Mentholmonooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","-",")","-menthol","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","1",",","4-menthane-3",",","8-diol","+","H","(","2",")","O","+","NADP","(","+",")"),4371576). assertion_content_comment('oboGo_MesaconylCoahydrataseactivity',s("Catalysis","of","the","hydration","of","mesaconyl-CoA","to","beta-methylmalyl-CoA","."),4326713). assertion_content_comment('oboGo_MesangialCellMatrixadhesion',s("The","binding","of","a","mesangial","cell","to","the","extracellular","matrix","via","adhesion","molecules",".","A","mesangial","cell","is","a","cell","that","encapsulates","the","capillaries","and","venules","in","the","kidney","."),4381215). assertion_content_comment('oboGo_MesenchymalEndodermalcellsignalinginvolvedinlunginduction',s("Any","process","that","mediates","the","transfer","of","information","from","a","mesenchymal","cell","to","an","endodermal","cell","in","the","foregut","and","contributes","to","the","formation","of","the","lung","bud","."),4116639). assertion_content_comment('oboGo_MesenchymalEndodermalcellsignaling',s("Any","process","that","mediates","the","transfer","of","information","between","a","mesenchymal","cell","and","an","endodermal","cell","."),4116589). assertion_content_comment('oboGo_MesenchymalEpithelialcellsignalinginvolvedinlungdevelopment',s("Any","process","that","mediates","the","transfer","of","information","from","a","mesenchymal","cell","to","an","epithelial","cell","and","contributes","to","the","development","of","the","lung","."),4116578). assertion_content_comment('oboGo_MesenchymalEpithelialcellsignalinginvolvedinprostateglanddevelopment',s("Any","process","that","mediates","the","transfer","of","information","from","a","mesenchymal","cell","to","an","epithelial","cell","where","it","is","received","and","interpreted","contributing","to","the","progression","of","the","prostate","gland","over","time","."),4110682). assertion_content_comment('oboGo_MesenchymalEpithelialcellsignalinginvolvedinprostateinduction',s("Signaling","at","short","range","from","urogenital","sinus","mesenchymal","cells","to","cells","of","the","urogenital","epithelium","resulting","in","the","epithelial","cells","adopting","a","prostatic","fate","."),4116822). assertion_content_comment('oboGo_MesenchymalEpithelialcellsignaling',s("Any","process","that","mediates","the","transfer","of","information","from","a","mesenchymal","cell","to","an","epithelial","cell","where","it","is","received","and","interpreted","."),4110678). assertion_content_comment('oboGo_MesodermalEndodermalcellsignalinginvolvedinheartinduction',s("Any","process","that","mediates","the","transfer","of","information","from","mesodermal","cells","to","endodermal","cells","that","contributes","to","heart","induction","."),4003547). assertion_content_comment('oboGo_MesodermalEndodermalcellsignaling',s("Any","process","that","mediates","the","transfer","of","information","from","mesodermal","cells","to","endodermal","cells","."),4003542). assertion_content_comment('oboGo_MesonephricCommaShapedbodymorphogenesis',s("The","process","in","which","the","mesonephric","comma-shaped","body","is","generated","and","organized",".","The","mesonephric","comma-shaped","body","is","the","precursor","structure","to","the","mesonephric","S-shaped","body","that","contributes","to","the","morphogenesis","of","a","nephron","in","the","mesonephros","."),4134041). assertion_content_comment('oboGo_MesonephricSShapedbodymorphogenesis',s("The","process","in","which","the","mesonephric","S-shaped","body","is","generated","and","organized",".","The","mesonephric","S-shaped","body","is","the","successor","of","the","mesonephric","comma-shaped","body","that","contributes","to","the","morphogenesis","of","a","nephron","in","the","mesonephros","."),4134155). assertion_content_comment('oboGo_MesoTartratedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","2R",",","3S",")","-tartrate","+","NAD","(","+",")","=","dihydroxyfumarate","+","H","(","+",")","+","NADH","."),4270744). assertion_content_comment('oboGo_MesothelialMesenchymalcellsignalinginvolvedinearlylungdevelopment',s("Any","process","that","mediates","the","transfer","of","information","from","a","mesothelial","cell","to","an","epithelial","cell","and","contributes","to","the","development","of","the","lung","."),4155980). assertion_content_comment('oboGo_MetabotropicGlutamateGABABLikereceptoractivity',s("OBSOLETE",".","A","G-protein","coupled","receptor","that","is","structurally/functionally","related","to","the","metabotropic","glutamate","receptor","."),4247296). assertion_content_comment('oboGo_MetalIncorporationIntoMetalloMolybdopterincomplex',s("The","incorporation","of","a","metal","into","a","metallo-molybdopterin","complex","."),4274462). assertion_content_comment('oboGo_MetalIncorporationIntoMetalloOxygencluster',s("The","formation","of","a","cluster","of","several","metal","atoms",",","including","manganese","or","calcium",",","with","one","or","more","bridging","(","mu-bond",")","oxygen","atoms",";","amino","acids","residues","in","proteins","that","may","ligate","the","metal","oxygen","cluster","are","histidine",",","aspartate",",","and","glutamate","."),4307577). assertion_content_comment('oboGo_MetalIncorporationIntoMetalloSulfurcluster',s("The","formation","of","a","cluster","of","several","metal","atoms",",","including","iron",",","nickel",",","molybdenum",",","vanadium",",","or","copper",",","with","one","or","more","bridging","(","mu-bond",")","sulfur","atoms",";","amino","acids","residues","in","proteins","that","may","ligate","the","metal","sulfur","cluster","are","cysteine",",","histidine",",","aspartate",",","glutamate",",","serine","and","cysteine","persulfide","."),4040422). assertion_content_comment('oboGo_MetalloSulfurclusterassembly',s("The","incorporation","of","a","metal","and","exogenous","sulfur","into","a","metallo-sulfur","cluster","."),4040409). assertion_content_comment('oboGo_MetanephricCommaShapedbodymorphogenesis',s("The","process","in","which","the","metanephric","comma-shaped","body","is","generated","and","organized",".","The","metanephric","comma-shaped","body","is","the","precursor","structure","to","the","metanephric","S-shaped","body","that","contributes","to","the","morphogenesis","of","a","nephron","in","the","metanephros","."),4124514). assertion_content_comment('oboGo_MetanephricSShapedbodymorphogenesis',s("The","process","in","which","the","metanephric","S-shaped","body","is","generated","and","organized",".","The","metanephric","S-shaped","body","is","the","successor","of","the","metanephric","comma-shaped","body","that","contributes","to","the","morphogenesis","of","a","nephron","in","the","metanephros","."),4124311). assertion_content_comment('oboGo_MethaneOxidizingorganelle',s("A","cytoplasmic",",","membrane-bounded","compartment","found","within","Methanotrophic","bacteria","that","contains","enzymes","and","electron","transfer","proteins","for","methane","catabolism",".","This","structure","is","analogous","to","the","thylakoid","of","Cyanobacteria","and","the","anammoxosome","of","anaerobic","ammonium","oxidation","organisms","."),4287961). assertion_content_comment('oboGo_Methanol_5_HydroxybenzimidazolylcobamideCo_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","5-hydroxybenzimidazolylcobamide","+","methanol","=","H2O","+","Co-methyl-Co-5-hydroxybenzimidazolylcob","(","I",")","amide","."),4365375). assertion_content_comment('oboGo_MethanolCommethyltransferasecomplex',s("A","heterotrimeric","protein","complex","composed","of","a","methanol","methyltransferase","subunit",",","a","corrinoid","protein","and","a","methanol-specific","corrinoid",":","coenzyme","M","methyltransferase","subunit",".","Catalyzes","the","transfer","of","a","methyl","group","from","methanol","to","coenzyme","M","as","part","of","the","pathway","of","methanogenesis","from","methanol","."),4327073). assertion_content_comment('oboGo_MethanolSpecificmethylcobalamin_Coenzymemmethyltransferaseactivity',s("Catalysis","of","the","transfer","of","the","methyl","group","from","the","methylated","corrinoid","cofactor","of","a","methanol","corrinoid","protein","to","coenzyme","M","."),4326865). assertion_content_comment('oboGo_MethanosarcinaPhenazinehydrogenaseactivity',s("Catalysis","of","the","reaction",":","H2","+","2-","(","2",",","3-dihydropentaprenyloxy",")","phenazine","=","2-dihydropentaprenyloxyphenazine","."),4183207). assertion_content_comment('oboGo_MethionineCatabolicProcessTo3Methylthiopropanoate',s("The","chemical","reactions","and","pathways","involving","the","catabolism","of","amino","acids","to","produce","carboxylic","acids","with","one","carbon","less","than","the","starting","amino","acid",".","In","S",".","cerevisiae",",","this","is","known","to","occur","for","leucine",",","isoleucine",",","valine",",","methionine",",","phenylalanine",",","tyrosine",",","or","tryptophan",".","When","methionine","is","used","as","the","substrate",",","3-methylthiopropanoate","is","produced",".","Often","referred","to","as","the","Ehrlich","pathway",",","these","reactions","generally","occur","during","fermentation","to","produce","a","variety","of","carboxylic","acids",",","sometimes","collectively","referred","to","as","fusel","acids",".","Depending","on","the","redox","state","of","the","cells",",","alcohol","derivatives","may","be","produced","instead","of","carboxylic","acids","."),4363305). assertion_content_comment('oboGo_MethionineCatabolicProcessTo3Methylthiopropanol',s("The","chemical","reactions","and","pathways","involving","the","catabolism","of","branched","chain","amino","acids","to","produce","branched","chain","alcohols","with","one","carbon","less","than","the","starting","amino","acid",".","In","S",".","cerevisiae",",","this","is","known","to","occur","for","leucine",",","isoleucine",",","valine",",","methionine",",","phenylalanine",",","tyrosine",",","or","tryptophan",".","When","methionine","is","used","as","the","substrate",",","3-methylthiopropanol","is","produced",".","Often","referred","to","as","the","Ehrlich","pathway",",","these","reactions","generally","occur","during","fermentation","to","produce","a","variety","of","alcohols",",","often","collectively","referred","to","as","fusel","alcohols",".","Depending","on","the","redox","state","of","the","cells",",","carboxylic","acid","derivatives","may","be","produced","instead","of","alcohols","."),4363157). assertion_content_comment('oboGo_MethionineCatabolicProcessToSuccinylCoa',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","methionine","into","other","compounds",",","including","succinyl-CoA","."),4241696). assertion_content_comment('oboGo_MethionineCatabolicProcessVia2Oxobutanoate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","methionine",",","via","the","intermediate","2-oxobutanoate","."),4241744). assertion_content_comment('oboGo_MethionineGammaLyaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","=","methanethiol","+","NH3","+","2-oxobutanoate","."),4273644). assertion_content_comment('oboGo_MethionineGlyoxylatetransaminaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","+","glyoxylate","=","4-methylthio-2-oxobutanoate","+","glycine","."),4270681). assertion_content_comment('oboGo_MethionineOxoAcidtransaminaseactivity',s("Catalysis","of","the","reaction",":","methionine","+","a","2-oxo","acid","=","2-oxo-4-methylthiobutanoate","+","an","amino","acid","."),4182850). assertion_content_comment('oboGo_MethionineRSulfoxidereductaseactivity',s("Catalysis","of","the","reaction",":","L-methionine","R-oxide","+","thioredoxin","=","L-methionine","+","thioredoxin","disulfide",";","can","act","on","free","oxidized","methionine","with","specificity","for","the","R","enantiomer",";","does","not","act","on","oxidized","methionine","in","peptide","linkage",".","Thioredoxin","disulfide","is","the","oxidized","form","of","thioredoxin","."),4179429). assertion_content_comment('oboGo_MethionineSMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","L-methionine","=","S-adenosyl-L-homocysteine","+","S-methyl-L-methionine","."),4308933). assertion_content_comment('oboGo_MethionineTrnaligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","L-methionine","+","tRNA","(","Met",")","=","AMP","+","diphosphate","+","L-methionyl-tRNA","(","Met",")"),4199814). assertion_content_comment('oboGo_MethionylTrnaaminoacylation',s("The","process","of","coupling","methionine","to","methionyl-tRNA",",","catalyzed","by","methionyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179506). assertion_content_comment('oboGo_MethionylTrnaformyltransferaseactivity',s("Catalysis","of","the","reaction",":","10-formyltetrahydrofolate","+","L-methionyl-tRNA","+","H2O","=","tetrahydrofolate","+","N-formylmethionyl-tRNA","."),4205489). assertion_content_comment('oboGo_MethylamineGlutamatenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","L-glutamate","+","methylammonium","=","N-methyl-L-glutamate","+","NH","(","4",")","(","+",")"),4365472). assertion_content_comment('oboGo_MethylamineSpecificmethylcobalamin_Coenzymemmethyltransferaseactivity',s("Catalysis","of","the","reaction",":","a","methylated","corrinoid","protein","+","coenzyme","M","=","a","corrinoid","protein","+","methyl-CoM",".","This","reaction","is","the","transfer","of","the","methyl","group","from","the","methylated","corrinoid","cofactor","of","a","methylamine","corrinoid","protein","to","coenzyme","M","."),4327287). assertion_content_comment('oboGo_MethylaspartateAmmoniaLyaseactivity',s("Catalysis","of","the","reaction",":","threo-3-methyl-L-aspartate","=","mesaconate","+","NH","(","4",")","(","+",")"),4270705). assertion_content_comment('oboGo_MethylatedDnaProteinCysteinesMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","DNA","(","containing","6-O-methylguanine",")","+","(","protein",")","-L-cysteine","=","DNA","(","without","6-O-methylguanine",")","+","protein","S-methyl-L-cysteine","."),4184023). assertion_content_comment('oboGo_MethylationDependentchromatinsilencing',s("Repression","of","transcription","by","methylation","of","DNA",",","leading","to","the","formation","of","heterochromatin","."),4148954). assertion_content_comment('oboGo_MethylCpgbinding',s("Interacting","selectively","and","non-covalently","with","a","methylated","cytosine/guanine","dinucleotide","."),4255220). assertion_content_comment('oboGo_MethylCpnpgbinding',s("Interacting","selectively","and","non-covalently","with","a","methylated","cytosine/unspecified/guanine","trinucleotide","."),4333490). assertion_content_comment('oboGo_MethylCpnpnbinding',s("Interacting","selectively","and","non-covalently","with","a","methylated","cytosine/unspecified/unspecified","trinucleotide","."),4333481). assertion_content_comment('oboGo_MethylcrotonoylCoacarboxylaseactivity',s("Catalysis","of","the","reaction",":","3-methylbut-2-enoyl-CoA","+","ATP","+","bicarbonate","=","trans-3-methylglutaconyl-CoA","+","ADP","+","2","H","(","+",")","+","phosphate","."),4206093). assertion_content_comment('oboGo_MethyleneFattyAcylPhospholipidsynthaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","phospholipid","olefinic","fatty","acid","=","S-adenosyl-L-homocysteine","+","phospholipid","methylene","fatty","acid","."),4206172). assertion_content_comment('oboGo_MethylenetetrahydrofolateDehydrogenaseNADPActivity_8',s("Catalysis","of","the","reaction",":","5",",","10-methylenetetrahydrofolate","+","NAD","(","P",")","+","=","5",",","10-methenyltetrahydrofolate","+","NAD","(","P",")","H","+","H","+"),4206081). assertion_content_comment('oboGo_Methylenetetrahydrofolate_TRNA_Uracil_5__MethyltransferaseFADH2_OxidizingActivity',s("Catalysis","of","the","reaction",":","FADH","+","H","+","+","tRNA","U","(","psi",")","C","=","FAD","+","+","tRNA","T","(","psi",")","C","+","THF","."),4365420). assertion_content_comment('oboGo_MethylglutaconylCoahydrataseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-3-hydroxy-3-methylglutaryl-CoA","=","trans-3-methylglutaconyl-CoA","+","H","(","2",")","O","."),4205971). assertion_content_comment('oboGo_MethylglyoxalCatabolicProcessToDLactate',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","methylglyoxal",",","CH3-CO-CHO",",","into","D-lactate","via","the","intermediate","S-lactoyl-glutathione",".","Glutathione","is","used","in","the","first","step","of","the","pathway","and","then","regenerated","in","the","second","step","."),4238501). assertion_content_comment('oboGo_MethylglyoxalReductaseNADHDependentactivity',s("Catalysis","of","the","reaction",":","(","R",")","-lactaldehyde","+","NAD","+","=","methylglyoxal","+","NADH","+","H","+"),4237754). assertion_content_comment('oboGo_MethylglyoxalReductaseNADPHDependentactivity',s("Catalysis","of","the","reaction",":","lactaldehyde","+","NADP","+","=","methylglyoxal","+","NADPH","+","H","+"),4328787). assertion_content_comment('oboGo_MethylIndole_3_AcetateEsteraseActivity',s("Catalysis","of","the","reaction",":","methyl","indole-3-acetate","+","H2O","=","indole-3-acetate","+","methanol","+","H","+"),4182245). assertion_content_comment('oboGo_MethylitaconateDeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","2-methylene-3-methylsuccinate","=","dimethylmaleate","."),4272049). assertion_content_comment('oboGo_MethylmalonateSemialdehydedehydrogenaseacylatingactivity',s("Catalysis","of","the","reaction",":","2-methyl-3-oxopropanoate","+","CoA","+","NAD","+","=","propanoyl-CoA","+","CO2","+","NADH","+","H","+"),4205958). assertion_content_comment('oboGo_MethylmalonylCoacarboxytransferaseactivity',s("Catalysis","of","the","reaction",":","pyruvate","+","D-methylmalonyl-CoA","=","oxaloacetic","acid","+","propionyl-CoA","."),4365343). assertion_content_comment('oboGo_MethylmalonylCoadecarboxylaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-2-methyl-3-oxopropanoyl-CoA","=","propanoyl-CoA","+","CO2","."),4206002). assertion_content_comment('oboGo_MethylmalonylCoaepimeraseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-methylmalonyl-CoA","=","(","S",")","-methylmalonyl-CoA","."),4205986). assertion_content_comment('oboGo_MethylmalonylCoamutaseactivity',s("Catalysis","of","the","reaction",":","(","R",")","-methylmalonyl-CoA","=","succinyl-CoA","."),4205923). assertion_content_comment('oboGo_MethylOnnAzoxymethanolbetaDGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","methylazoxymethanol","+","UDP-D-glucose","=","H","+","+","cycasin","+","UDP","."),4366928). assertion_content_comment('oboGo_Methylquercetagetin6OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","3","'",",","4","'",",","5",",","6-tetrahydroxy-3",",","7-dimethoxyflavone","+","S-adenosyl-L-methionine","(","1","+",")","=","3","'",",","4","'",",","5-trihydroxy-3",",","6",",","7-trimethoxyflavone","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308630). assertion_content_comment('oboGo_MethylTertButylethermetabolicprocess',s("The","chemical","reactions","and","pathways","involving","methyl","tert-butyl","ether",",","2-methoxy-2-methylpropane",".","Methyl","tert-butyl","ether","is","a","synthetic","chemical","which","is","mixed","with","gasoline","for","use","in","reformulated","gasoline",".","It","was","first","introduced","as","an","additive","for","unleaded","gasoline","in","the","1980s",".","It","is","also","used","as","a","laboratory","reagent","and","a","pharmaceutical","agent","."),4272431). assertion_content_comment('oboGo_MethylTertiaryButylEther3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","methyl","tert-butyl","ether","+","1/2","O2","=","tert-butyl","alcohol","+","formaldehyde","."),4275647). assertion_content_comment('oboGo_Methyltetrahydroprotoberberine14Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","O2","+","NADPH","+","H","+","+","(","S",")","-N-methylcanadine","=","H2O","+","NADP","+","+","allocryptopine","."),4365018). assertion_content_comment('oboGo_Methylthioribulose1Phosphatedehydrataseactivity',s("Catalysis","of","the","reaction",":","S-methyl-5-thio-D-ribulose","1-phosphate","=","5-","(","methylthio",")","-2",",","3-dioxopentyl","phosphate","+","H","(","2",")","O","."),4358922). assertion_content_comment('oboGo_MethylTransferDrivenactivetransmembranetransporteractivity',s("Primary","active","transport","of","a","solute","across","a","membrane","driven","by","a","methyl","transfer","reaction",".","Primary","active","transport","is","catalysis","of","the","transport","of","a","solute","across","a","membrane",",","up","the","solute","'","s","concentration","gradient",",","by","binding","the","solute","and","undergoing","a","series","of","conformational","changes",".","Transport","works","equally","well","in","either","direction","and","is","driven","by","a","primary","energy","source","."),4291739). assertion_content_comment('oboGo_MethylumbelliferylAcetatedeacetylaseactivity',s("Catalysis","of","the","reaction",":","4-methylumbelliferyl","acetate","+","H","(","2",")","O","=","4-methylumbelliferone","+","acetate","+","H","(","+",")"),4368762). assertion_content_comment('oboGo_MHCClassIIReceptorActivity_1',s("OBSOLETE",".","A","major","histocompatibility","complex","class","II","receptor",".","These","display","processed","antigens","from","virally-infected","or","transformed","cells",".","Class-II-positive","cells","(","'","antigen-presenting","cells","'",")","can","take","up","antigens","from","outside","by","endocytosis",",","degrade","them","into","small","peptides",",","and","re-export","the","peptides","(","now","bound","to","MHC","class","II","protein",")","to","the","cell","surface",".","These","peptide-MHC","class","II","complexes","can","then","be","recognized","by","specific","CD4","+","lymphocytes","."),4300560). assertion_content_comment('oboGo_MHCClassIReceptorActivity_8',s("OBSOLETE",".","A","major","histocompatibility","complex","class","I","receptor",".","These","display","processed","antigens","from","the","endocytosed","bacteria",".","MHC","class","I","proteins","can","form","complexes","with","processed","antigen","peptides","only","if","the","antigen","is","synthesized","in","the","same","cell",".","As","a","consequence",",","T","lymphocytes","can","only","bind","to","class-I-positive","cells","that","are","synthesizing","the","antigen","(","e.g",".","virus-infected","cells",")"),4310967). assertion_content_comment('oboGo_MHCInteractingprotein',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4187943). assertion_content_comment('oboGo_MicrocinE492BiosyntheticProcessBySiderophoreEsterModificationOfPeptidylSerine',s("The","modification","of","serine","to","N-","[","5-","(","6-O-seryl-beta-glucosyl",")","-2",",","3-dihydroxybenzoyl","]","-O-","[","N-","(","2",",","3-dihydroxybenzoyl",")","-O-","[","N-","(","2",",","3-dihydroxybenzoyl",")","seryl","]","seryl","]","serine","as","found","in","microcin","E492","produced","from","the","mceA","gene","in","plasmid","pJAM229","of","the","E",".","coli","VCS257","strain","and","the","K",".","pneumoniae","RYC492","strain","."),4287568). assertion_content_comment('oboGo_MicropexophagySpecificmembraneapparatus',s("A","membrane-bounded","flattened","sac","that","is","formed","during","micropexophagy","between","the","membrane","tips","of","an","engulfing","vacuole",",","completing","the","engulfment","and","sequestration","of","peroxisomes","from","the","cytosol",",","and","forming","a","micropexophagic","body","within","the","lumen","of","the","vacuole","."),4330230). assertion_content_comment('oboGo_MicroRibonucleoproteincomplex',s("A","complex","containing","both","protein","and","micro-RNA","(","miRNA",")","molecules",".","miRNAs","are","approximately","22","nucleotide","noncoding","RNAs","derived","from","endogenous","genes",";","they","are","processed","from","the","stem","of","a","longer","hairpin","like","structure","termed","a","pre-miRNA","."),4381838). assertion_content_comment('oboGo_MicrotubuleBasedflagellarcellmotility',s("Cell","motility","due","to","the","motion","of","one","or","more","microtubule-based","flagella",".","A","microtubule-based","flagellum","is","a","long",",","whiplike","protrusion","from","the","surface","of","a","eukaryotic","cell","that","is","similar","in","structure","to","a","cilium","."),4168498). assertion_content_comment('oboGo_MicrotubuleBasedflagellarcytoplasm',s("All","of","the","contents","of","a","microtubule-based","flagellum",",","excluding","the","plasma","membrane","surrounding","the","flagellum","."),4073072). assertion_content_comment('oboGo_MicrotubuleBasedflagellumpart',s("Any","constituent","part","of","a","microtubule-based","flagellum",",","a","long",",","whiplike","protrusion","from","the","surface","of","a","eukaryotic","cell",",","whose","undulations","drive","the","cell","through","a","liquid","medium",";","similar","in","structure","to","a","cilium",".","The","flagellum","is","based","on","a","9","+","2","arrangement","of","microtubules",".","Examples","of","this","component","are","found","in","Mus","musculus","."),4041950). assertion_content_comment('oboGo_MicrotubuleBasedflagellum',s("A","long",",","whiplike","protrusion","from","the","surface","of","a","eukaryotic","cell",",","whose","undulations","drive","the","cell","through","a","liquid","medium",";","similar","in","structure","to","a","cilium",".","The","flagellum","is","based","on","a","9","+","2","arrangement","of","microtubules","."),4041948). assertion_content_comment('oboGo_MicrotubuleBasedmovement',s("A","microtubule-based","process","that","is","mediated","by","motor","proteins","and","results","in","the","movement","of","organelles",",","other","microtubules",",","or","other","particles","along","microtubules","."),3977900). assertion_content_comment('oboGo_MicrotubuleBasedperoxisomelocalization',s("The","microtubule-based","process","in","which","a","peroxisome","is","transported","to",",","and/or","maintained","in",",","a","specific","location",".","A","peroxisome","is","a","small","membrane-bounded","organelle","that","uses","dioxygen","(","O2",")","to","oxidize","organic","molecules","."),4159813). assertion_content_comment('oboGo_MicrotubuleBasedprocess',s("Any","cellular","process","that","depends","upon","or","alters","the","microtubule","cytoskeleton",",","that","part","of","the","cytoskeleton","comprising","microtubules","and","their","associated","proteins","."),3969262). assertion_content_comment('oboGo_MicrotubuleBasedtransport',s("Microtubule-based","movement","that","results","in","the","net",",","directed","movement","of","organelles","or","other","particles","from","one","location","in","the","cell","to","another","."),3977914). assertion_content_comment('oboGo_MicrotubuleMinusEndbinding',s("Interacting","selectively","and","non-covalently","with","the","minus","end","of","a","microtubule","."),4279120). assertion_content_comment('oboGo_MicrotubulePlusEndbinding',s("Interacting","selectively","and","non-covalently","with","the","plus","end","of","a","microtubule","."),4279129). assertion_content_comment('oboGo_MicrotubuleSeveringatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","Catalysis","of","the","severing","of","a","microtubule","at","a","specific","spot","along","its","length",",","coupled","to","the","hydrolysis","of","ATP","."),4252441). assertion_content_comment('oboGo_MidbrainHindbrainboundarydevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","the","midbrain-hindbrain","boundary","over","time",",","from","its","formation","to","the","mature","structure",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages","."),4042599). assertion_content_comment('oboGo_MidbrainHindbrainboundaryinitiation',s("The","regionalization","process","that","gives","rise","to","the","midbrain-hindbrain","boundary",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4044889). assertion_content_comment('oboGo_MidbrainHindbrainboundarymaturationduringbraindevelopment',s("A","developmental","process","occurring","after","the","brain","has","been","specified","along","the","neural","axis","that","is","required","for","the","midbrain-hindbrain","boundary","to","attain","its","fully","functional","state",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4053332). assertion_content_comment('oboGo_MidbrainHindbrainboundarymaturationduringneuralplatedevelopment',s("A","developmental","process","occurring","before","the","brain","has","been","specified","along","the","neural","axis","that","is","required","for","the","midbrain-hindbrain","boundary","to","attain","its","fully","functional","state",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4053369). assertion_content_comment('oboGo_MidbrainHindbrainboundarymaturation',s("A","developmental","process",",","independent","of","morphogenetic","(","shape",")","change",",","that","is","required","for","the","midbrain-hindbrain","boundary","to","attain","its","fully","functional","state",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4042615). assertion_content_comment('oboGo_MidbrainHindbrainboundarymorphogenesis',s("The","process","in","which","the","anatomical","structure","of","the","midbrain-hindbrain","boundary","is","generated","and","organized",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4044917). assertion_content_comment('oboGo_MidbrainHindbrainboundarystructuralorganization',s("The","process","that","contributes","to","the","act","of","creating","the","structural","organization","of","the","midbrain-hindbrain","boundary","structure",".","The","midbrain-hindbrain","domain","of","the","embryonic","brain","is","comprised","of","the","mesencephalic","vesicle","and","the","first","rhombencephalic","vesicle","at","early","somitogenesis","stages",".","An","organizing","center","at","the","boundary","patterns","the","midbrain","and","hindbrain","primordia","of","the","neural","plate","."),4044930). assertion_content_comment('oboGo_MiddleLamellaContainingextracellularmatrix',s("The","matrix","external","to","the","cell",",","composed","of","the","cell","wall","and","middle","lamella","."),4023045). assertion_content_comment('oboGo_MinusEnddirectedmicrofilamentmotoractivity',s("Catalysis","of","movement","along","a","microfilament","towards","the","minus","end",",","coupled","to","the","hydrolysis","of","a","nucleoside","triphosphate","(","usually","ATP",")","The","minus","end","of","an","actin","filament","is","the","end","that","does","not","preferentially","add","actin","monomers","."),4159571). assertion_content_comment('oboGo_MinusEndDirectedmicrotubulemotoractivity',s("Catalysis","of","movement","along","a","microtubule","toward","the","minus","end",",","coupled","to","the","hydrolysis","of","ATP","(","or","GTP",")"),4252452). assertion_content_comment('oboGo_MinusEnddirectedmicrotubulesliding',s("The","movement","of","one","microtubule","along","another","microtubule",",","where","the","motion","is","directed","towards","the","minus","ends","of","the","microtubules","."),4321970). assertion_content_comment('oboGo_MinusEndDirectedorganelletransportalongmicrotubule',s("The","directed","movement","of","an","organelle","towards","the","minus","end","of","a","microtubule",",","mediated","by","motor","proteins",".","This","process","begins","with","the","attachment","of","an","organelle","to","a","microtubule",",","and","ends","when","the","organelle","reaches","its","final","destination","."),4158783). assertion_content_comment('oboGo_MinusEndDirectedvesicletransportalongmicrotubule',s("The","directed","movement","of","a","vesicle","towards","the","minus","end","of","a","microtubule",",","mediated","by","motor","proteins",".","This","process","begins","with","the","attachment","of","a","vesicle","to","a","microtubule",",","and","ends","when","the","vesicle","reaches","its","final","destination","."),4158787). assertion_content_comment('oboGo_MinusEndkinesincomplex',s("Any","complex","that","includes","a","dimer","of","molecules","from","the","kinesin","superfamily","and","any","associated","proteins",",","and","moves","towards","the","minus","end","of","a","microtubule","."),4221538). assertion_content_comment('oboGo_Mis6Sim4complex',s("A","protein","complex","that","forms","part","of","the","inner","centromere",",","which","is","involved","in","the","loading","of","the","centromeric","histone","h3","variant","CENP-A","onto","centromeres","and","in","centromere","specific","heterochromatin","formation",".","The","complex","contains","about","12","proteins",",","of","which","two","are","known","as","Mis6","and","Sim4","in","S",".","pombe","and","CENP-I","and","CENP-H","in","human","."),4060720). assertion_content_comment('oboGo_MismatchBasePairDNANGlycosylaseactivity',s("Catalysis","of","the","removal","of","single","bases","present","in","mismatches","by","the","cleavage","the","N-C1","'","glycosidic","bond","between","the","target","damaged","DNA","base","and","the","deoxyribose","sugar",".","The","reaction","releases","a","free","base","and","leaves","an","apurinic/apyrimidinic","(","AP",")","site","."),4256144). assertion_content_comment('oboGo_MismatchRepairInvolvedInMaintenanceOfFidelityInvolvedInDNADependentdnareplication',s("A","mismatch","repair","process","that","corrects","errors","introduced","that","ensures","the","accuracy","of","DNA","replication","."),4176675). assertion_content_comment('oboGo_MitochondriaAssociatedproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","proteins","transported","from","mitochondria","and","targeted","to","cytoplasmic","proteasomes","for","degradation","as","a","response","to","oxidative","stress","conditions","."),4157981). assertion_content_comment('oboGo_MitochondrialAlanylTrnaaminoacylation',s("The","process","of","coupling","alanine","to","alanyl-tRNA","in","a","mitochondrion",",","catalyzed","by","alanyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179822). assertion_content_comment('oboGo_MitochondrialAlphaKetoglutaratedehydrogenasecomplex',s("Mitochondrial","complex","that","possesses","alpha-ketoglutarate","dehydrogenase","activity","."),4221130). assertion_content_comment('oboGo_MitochondrialAlphaKetoglutaratemalatetransport',s("OBSOLETE",".","The","directed","movement","of","alpha-ketoglutarate","and","malate","into",",","out","of","or","within","a","mitochondrion","."),4228504). assertion_content_comment('oboGo_MitochondrialArginylTrnaaminoacylation',s("The","process","of","coupling","arginine","to","arginyl-tRNA","in","a","mitochondrion",",","catalyzed","by","arginyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179842). assertion_content_comment('oboGo_MitochondrialAsparaginylTrnaaminoacylation',s("The","process","of","coupling","asparagine","to","asparaginyl-tRNA","in","a","mitochondrion",",","catalyzed","by","asparaginyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179862). assertion_content_comment('oboGo_MitochondrialAspartylTrnaaminoacylation',s("The","process","of","coupling","aspartate","to","aspartyl-tRNA","in","a","mitochondrion",",","catalyzed","by","aspartyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179882). assertion_content_comment('oboGo_MitochondrialCysteinylTrnaaminoacylation',s("The","process","of","coupling","cysteine","to","cysteinyl-tRNA","in","a","mitochondrion",",","catalyzed","by","cysteinyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179762). assertion_content_comment('oboGo_MitochondrialDNADirectedrnapolymerasecomplex',s("A","DNA-directed","RNA","polymerase","complex","located","in","the","mitochondrion",".","Mitochondrial","RNA","polymerase","is","composed","of","two","subunits",",","a","catalytic","core",",","which","resembles","the","enzymes","from","bacteriophage","T7","and","T3",",","and","a","specificity","factor","required","for","promoter","recognition",",","which","is","similar","to","members","of","the","eubacterial","sigma","factor","family",".","In","S",".","cerevisiae",",","these","are","encoded","by","the","nuclear","genes","RPO41","and","MTF1","and","the","specificity","factor",",","required","for","promoter","recognition","and","initiation",",","is","not","present","in","the","elongating","form","."),4359543). assertion_content_comment('oboGo_MitochondrialGlutaminylTrnaaminoacylation',s("The","process","of","coupling","glutamine","to","glutaminyl-tRNA","in","a","mitochondrion",",","catalyzed","by","glutaminyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179782). assertion_content_comment('oboGo_MitochondrialGlutamylTrnaaminoacylation',s("The","process","of","coupling","glutamate","to","glutamyl-tRNA","in","a","mitochondrion",",","catalyzed","by","glutamyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179802). assertion_content_comment('oboGo_MitochondrialGlycylTrnaaminoacylation',s("The","process","of","coupling","glycine","to","glycyl-tRNA","in","a","mitochondrion",",","catalyzed","by","glycyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179702). assertion_content_comment('oboGo_MitochondrialHeavyStrandPromoterAntiSensebinding',s("Interacting","selectively","and","non-covalently","with","the","anti-sense","strand","of","the","heavy","strand","promoter",",","a","promoter","located","on","the","heavy",",","or","guanine-rich",",","strand","of","mitochondrial","DNA","."),4173427). assertion_content_comment('oboGo_MitochondrialHistidylTrnaaminoacylation',s("The","process","of","coupling","histidine","to","histidyl-tRNA","in","a","mitochondrion",",","catalyzed","by","histidyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179682). assertion_content_comment('oboGo_MitochondrialIsoleucylTrnaaminoacylation',s("The","process","of","coupling","isoleucine","to","isoleucyl-tRNA","in","a","mitochondrion",",","catalyzed","by","isoleucyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179742). assertion_content_comment('oboGo_MitochondrialLeucylTrnaaminoacylation',s("The","process","of","coupling","leucine","to","leucyl-tRNA","in","a","mitochondrion",",","catalyzed","by","leucyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179722). assertion_content_comment('oboGo_MitochondrialLightStrandPromoterAntiSensebinding',s("Interacting","selectively","and","non-covalently","with","the","anti-sense","strand","of","the","light","strand","promoter",",","a","promoter","located","on","the","light",",","or","cytosine-rich",",","strand","of","mitochondrial","DNA","."),4173438). assertion_content_comment('oboGo_MitochondrialLysylTrnaaminoacylation',s("The","process","of","coupling","lysine","to","lysyl-tRNA","in","a","mitochondrion",",","catalyzed","by","lysyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179489). assertion_content_comment('oboGo_MitochondrialMethionylTrnaaminoacylation',s("The","process","of","coupling","methionine","to","methionyl-tRNA","in","a","mitochondrion",",","catalyzed","by","methionyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179509). assertion_content_comment('oboGo_MitochondrialPhenylalanylTrnaaminoacylation',s("The","process","of","coupling","phenylalanine","to","phenylalanyl-tRNA","in","a","mitochondrion",",","catalyzed","by","phenylalanyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179449). assertion_content_comment('oboGo_MitochondrialProlylTrnaaminoacylation',s("The","process","of","coupling","proline","to","prolyl-tRNA","in","a","mitochondrion",",","catalyzed","by","prolyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179469). assertion_content_comment('oboGo_MitochondrialProteinTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",";","drives","the","transport","of","proteins","into","the","mitochondrion","via","the","mitochondrial","inner","membrane","translocase","complex","."),4252500). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecatalyticcore',s("The","hexamer",",","comprising","three","alpha","and","three","beta","subunits",",","that","possesses","the","catalytic","activity","of","the","mitochondrial","hydrogen-transporting","ATP","synthase","."),4007499). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecentralstalk',s("One","of","two","stalks","that","connect","the","catalytic","core","of","the","hydrogen-transporting","ATP","synthase","to","the","mitochondrial","membrane-associated","F0","proteins",";","rotates","within","the","catalytic","core","during","catalysis","."),4007806). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","proton-transporting","ATP","synthase","in","the","mitochondrial","inner","membrane","."),4063565). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecomplexcatalyticcoref1',s("The","catalytic","sector","of","the","mitochondrial","hydrogen-transporting","ATP","synthase",";","it","comprises","the","catalytic","core","and","central","stalk",",","and","is","peripherally","associated","with","the","mitochondrial","inner","membrane","when","the","entire","ATP","synthase","is","assembled","."),3974159). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecomplexcouplingfactorfo',s("All","non-F1","subunits","of","the","mitochondrial","hydrogen-transporting","ATP","synthase",",","including","integral","and","peripheral","mitochondrial","inner","membrane","proteins","."),3974188). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasecomplex',s("A","proton-transporting","ATP","synthase","complex","found","in","the","mitochondrial","membrane","."),3974133). assertion_content_comment('oboGo_MitochondrialProtonTransportingatpsynthasestatorstalk',s("One","of","two","stalks","that","connect","the","catalytic","core","of","the","hydrogen-transporting","ATP","synthase","to","the","mitochondrial","membrane-associated","F0","proteins",";","is","thought","to","prevent","futile","rotation","of","the","catalytic","core","."),3974213). assertion_content_comment('oboGo_MitochondrialRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","an","RNA","molecule","transcribed","from","a","mitochondrial","genome",";","occurs","in","the","mitochondrion","."),4157917). assertion_content_comment('oboGo_MitochondrialRNA5Endprocessing',s("Any","process","involved","in","forming","the","mature","5","'","end","of","an","RNA","molecule","transcribed","from","a","mitochondrial","genome",";","occurs","in","the","mitochondrion","."),4363237). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseCorePromoterProximalRegionSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","mitochondrial","RNA","polymerase","."),4356397). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseCorePromoterProximalRegionSequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","in","cis","with","and","relatively","close","to","a","core","promoter","for","a","mitochondrial","RNA","polymerase","in","order","to","modulate","transcription","by","mitochondrial","RNA","polymerase",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex","."),4358323). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseCorePromoterSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","part","of","the","core","promoter","for","the","mitochondrial","RNA","polymerase","."),4363409). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseCorePromoterSequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","specific","DNA","sequence","that","is","part","of","the","core","promoter","for","mitochondrial","RNA","polymerase","in","order","to","modulate","transcription","by","mitochondrial","RNA","polymerase",".","The","transcription","factor","may","or","may","not","also","interact","selectively","with","a","protein","or","macromolecular","complex","."),4358342). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseRegulatoryRegionSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","specific","sequence","of","DNA","that","controls","the","transcription","of","a","region","of","DNA","by","mitochondrial","RNA","polymerase","."),4356367). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseTerminationSiteSequenceSpecificdnabinding',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","a","terminator","for","mitochondrial","RNA","polymerase","."),4358314). assertion_content_comment('oboGo_MitochondrialRNAPolymeraseTerminatorSiteSequenceSpecificdnabindingtranscriptionfactoractivity',s("Interacting","selectively","and","non-covalently","with","a","sequence","of","DNA","that","is","a","terminator","for","mitochondrial","RNA","polymerase","in","order","to","promote","transcription","termination","by","mitochondrial","RNA","polymerase","."),4358293). assertion_content_comment('oboGo_MitochondrialSerylTrnaaminoacylation',s("The","process","of","coupling","serine","to","seryl-tRNA","in","a","mitochondrion",",","catalyzed","by","seryl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179529). assertion_content_comment('oboGo_MitochondrialSingleSubunittypernapolymerasebinding',s("Interacting","selectively","and","non-covalently","with","a","single","subunit","mitochondrial","RNA","polymerase","enzyme",",","which","is","composed","of","a","single","catalytic","subunit","similar","to","the","RNA","polymerase","enzymes","from","phages","T3",",","T7",",","and","SP6","."),4356981). assertion_content_comment('oboGo_MitochondrialThreonylTrnaaminoacylation',s("The","process","of","coupling","threonine","to","threonyl-tRNA","in","a","mitochondrion",",","catalyzed","by","threonyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179549). assertion_content_comment('oboGo_MitochondrialTRNA3Trailercleavageendonucleolytic',s("Endonucleolytic","cleavage","of","the","3","'","-end","of","the","pre-tRNA","as","part","of","the","process","of","generating","the","mature","3","'","-end","of","the","tRNA","in","the","mitochondrion","."),4157958). assertion_content_comment('oboGo_MitochondrialTRNAThioModification',s("The","addition","a","sulfur","atom","to","a","nucleotide","in","a","mitochondrial","tRNA","molecule","."),4178196). assertion_content_comment('oboGo_MitochondrialTryptophanylTrnaaminoacylation',s("The","process","of","coupling","tryptophan","to","tryptophanyl-tRNA","in","a","mitochondrion",",","catalyzed","by","tryptophanyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179204). assertion_content_comment('oboGo_MitochondrialTyrosylTrnaaminoacylation',s("The","process","of","coupling","threonine","to","tyrosyl-tRNA","in","a","mitochondrion",",","catalyzed","by","tyrosyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179224). assertion_content_comment('oboGo_MitochondrialValylTrnaaminoacylation',s("The","process","of","coupling","valine","to","valyl-tRNA","in","a","mitochondrion",",","catalyzed","by","valyl-tRNA","synthetase",".","In","tRNA","aminoacylation",",","the","amino","acid","is","first","activated","by","linkage","to","AMP","and","then","transferred","to","either","the","2","'","-","or","the","3","'","-hydroxyl","group","of","the","3","'","-adenosine","residue","of","the","tRNA","."),4179244). assertion_content_comment('oboGo_MitochondriaNucleussignalingpathway',s("A","series","of","molecular","signals","that","forms","a","pathway","of","communication","from","the","mitochondria","to","the","nucleus","and","initiates","cellular","changes","in","response","to","changes","in","mitochondrial","function","."),4320307). assertion_content_comment('oboGo_MitogenActivatedproteinkinasebinding',s("Interacting","selectively","and","non-covalently","with","a","mitogen-activated","protein","kinase","."),4215468). assertion_content_comment('oboGo_MitogenActivatedproteinkinasekinasebinding',s("Interacting","selectively","and","non-covalently","with","a","mitogen-activated","protein","kinase","kinase",",","any","protein","that","can","phosphorylate","a","MAP","kinase","."),4321257). 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assertion_content_comment('oboGo_ModulationBySymbiontOfHostSignalTransductionMediatedByGProteinalphasubunit',s("Any","process","in","which","the","symbiont","modulates","the","frequency",",","rate","or","extent","of","the","host","signal","transduction","mediated","by","G-protein","alpha","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4152881). assertion_content_comment('oboGo_ModulationBySymbiontOfHostSignalTransductionMediatedByGProteinbetasubunit',s("Any","process","in","which","the","symbiont","modulates","the","frequency",",","rate","or","extent","of","the","host","signal","transduction","mediated","by","G-protein","beta","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4152913). assertion_content_comment('oboGo_ModulationBySymbiontOfHostSignalTransductionMediatedByGProteingammasubunit',s("Any","process","in","which","the","symbiont","modulates","the","frequency",",","rate","or","extent","of","the","host","signal","transduction","mediated","by","G-protein","gamma","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153441). assertion_content_comment('oboGo_ModulationBySymbiontOfHostTCellmediatedimmuneresponse',s("Any","process","in","which","an","organism","modulates","the","frequency",",","rate","or","extent","of","the","T-cell","mediated","immune","response","of","the","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4194409). 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assertion_content_comment('oboGo_MoltingCycleCollagenAndCuticulinBasedcuticle',s("The","periodic","shedding","of","part","or","all","of","a","collagen","and","cuticulin-based","cuticle",",","which","is","then","replaced","by","a","new","collagen","and","cuticulin-based","cuticle",".","An","example","of","this","is","found","in","the","Nematode","worm",",","Caenorhabditis","elegans","."),4078449). assertion_content_comment('oboGo_MoltingCycleProteinBasedcuticle',s("The","periodic","shedding","of","part","or","all","of","a","protein-based","cuticle",",","which","is","then","replaced","by","a","new","protein-based","cuticle",".","A","cuticle","is","the","outer","layer","of","an","animal","which","acts","to","prevent","water","loss","."),4015241). assertion_content_comment('oboGo_MolybdateTransmembraneTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","molybdate","(","out",")","=","ADP","+","phosphate","+","molybdate","(","in",")"),4291486). assertion_content_comment('oboGo_MolybdenumIncorporationIntoIronSulfurcluster',s("The","incorporation","of","molybdenum","into","an","iron-sulfur","cluster","."),4280794). assertion_content_comment('oboGo_MolybdenumIncorporationIntoMetalloSulfurcluster',s("The","incorporation","of","molybdenum","into","a","metallo-sulfur","cluster","."),4280791). assertion_content_comment('oboGo_MolybdenumIncorporationIntoMolybdenumMolybdopterincomplex',s("The","incorporation","of","molybdenum","into","a","molybdenum-molybdopterin","complex","."),4274464). 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assertion_content_comment('oboGo_MolybdenumIncorporationViaLSelenocysteinylmolybdenumbismolybdopteringuaninedinucleotide',s("The","incorporation","of","molybdenum","into","a","protein","via","L-selenocysteinyl","molybdenum","bis","(","molybdopterin","guanine","dinucleotide",")"),4284802). assertion_content_comment('oboGo_MolybdenumIncorporationViaLSerinylmolybdopteringuaninedinucleotide',s("The","incorporation","of","molybdenum","into","a","protein","via","L-serinyl","molybdopterin","guanine","dinucleotide","."),4314608). assertion_content_comment('oboGo_MolybdenumIronnitrogenaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","8","reduced","ferredoxin","+","8","H","+","+","N2","+","16","ATP","=","8","oxidized","ferredoxin","+","2","NH3","+","16","ADP","+","16","phosphate","."),4301424). 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assertion_content_comment('oboGo_MoMolybdopterincofactorcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","Mo-molybdopterin","cofactor",",","essential","for","the","catalytic","activity","of","some","enzymes",".","The","cofactor","consists","of","a","mononuclear","molybdenum","(","Mo",")","ion","coordinated","by","one","or","two","molybdopterin","ligands","."),4333764). assertion_content_comment('oboGo_MoMolybdopterincofactormetabolicprocess',s("The","chemical","reactions","and","pathways","involving","the","Mo-molybdopterin","cofactor",",","essential","for","the","catalytic","activity","of","some","enzymes",".","The","cofactor","consists","of","a","mononuclear","molybdenum","(","Mo",")","ion","coordinated","by","one","or","two","molybdopterin","ligands","."),4230078). assertion_content_comment('oboGo_MoMolybdopterincofactorsulfuraseactivity',s("Catalysis","of","the","sulfurylation","of","the","desulfo","form","of","molybdenum","cofactor","(","MoCo",")",",","a","cofactor","required","for","the","activity","of","some","enzymes",",","such","as","aldehyde","oxidase","."),4256115). assertion_content_comment('oboGo_MoMolybdopterinoxidoreductaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4304194). assertion_content_comment('oboGo_MoMolybdopterinsynthaseactivity',s("Catalysis","of","the","conversion","of","precursor","Z","to","molybdopterin",",","the","final","step","in","molybdopterin","biosynthesis","."),4309833). assertion_content_comment('oboGo_Mon1Ccz1complex',s("A","protein","complex","that","functions","as","a","guanine","nucleotide","exchange","factor","(","GEF",")","and","converts","Rab-GDP","to","Rab-GTP",".","In","S",".","cerevisiae",",","this","complex","consists","of","at","least","Mon1","and","Ccz1",",","and","serves","as","a","GEF","for","the","Rab","Ypt7p","."),4082858). assertion_content_comment('oboGo_MonoAdpDRibosebinding',s("Interacting","selectively","and","non-covalently","with","monomeric","ADP-D-ribose",",","an","ADP-aldose","having","ribose","as","the","aldose","fragment","."),4157775). assertion_content_comment('oboGo_MonoButyltindioxygenaseactivity',s("Catalysis","of","the","reaction",":","butyltin","+","O2","+","2","H","+","+","2","e-","=","H2O","+","beta-hydroxybutyltin","."),4275425). assertion_content_comment('oboGo_MonocarboxylicAcidTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","monocarboxylic","acid","(","out/in",")","=","ADP","+","phosphate","+","monocarboxylic","acid","(","in/out",")"),4337826). assertion_content_comment('oboGo_MonoclusterBacterialTypeferredoxin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4259394). assertion_content_comment('oboGo_MonocoumaroylDicaffeoylSpermidineMetaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","monocoumaroyl","dicaffeoyl","spermidine","+","NADPH","+","O2","=","tricaffeoyl","spermidine","+","NADP","+","+","H2O","."),4156974). assertion_content_comment('oboGo_MonocyteChemotacticProtein_1Production',s("The","appearance","of","monocyte","chemotactic","protein-1","due","to","biosynthesis","or","secretion","following","a","cellular","stimulus",",","resulting","in","an","increase","in","its","intracellular","or","extracellular","levels","."),4130182). assertion_content_comment('oboGo_MonoferuloylDiHydroxyferuloylspermidinemetaHydroxylaseactivity',s("Catalysis","of","the","reaction",":","monoferuloyl","di-","(","hydroxyferuloyl",")","spermidine","+","NADPH","+","O2","=","tri-","(","hydroxyferuloyl",")","spermidine","+","NADP","+","+","H2O","."),4157879). assertion_content_comment('oboGo_MonolayerSurroundedlipidstoragebodyouterlipidmonolayer',s("The","single","layer","of","phopholipids","surrounding","a","lipid","storage","body","."),4074481). assertion_content_comment('oboGo_MonolayerSurroundedlipidstoragebody',s("A","subcellular","organelle","of","plant","cells","surrounded","by","'","half-unit","'","or","a","monolayer","membrane","instead","of","the","more","usual","bilayer",".","The","storage","body","has","a","droplet","of","triglyceride","surrounded","by","a","monolayer","of","phospholipids",",","interacting","with","the","triglycerides","and","the","hydrophilic","head","groups","facing","the","cytosol",",","and","containing","major","protein","components","called","oleosins","."),4074466). assertion_content_comment('oboGo_MonomethylSulfataseactivity',s("Catalysis","of","the","reaction",":","H","(","2",")","O","+","monomethyl","sulfate","=","H","(","+",")","+","methanol","+","sulfate","."),4271987). assertion_content_comment('oboGo_MonoOleintransacylationactivity',s("Catalysis","of","the","reaction",":","mono-olein","+","mono-olein","=","diolein","+","glycerol",".","Mono-olein",",","also","known","as","mono-oleoylglycerol",",","is","the","monoglyceride","formed","from","oleic","acid",",","9-octodecenoic","acid",";","diolein","is","also","known","as","dioleoylglycerol","."),4287580). assertion_content_comment('oboGo_MonosaccharideTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","monosaccharide","(","out",")","=","ADP","+","phosphate","+","monosaccharide","(","in",")","Ribose",",","xylose",",","arabinose",",","galactose","and","methylgalactoside","are","imported","."),4289537). assertion_content_comment('oboGo_MonoterpenolBetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","(","-",")","-menthol","+","UDP-D-glucose","=","(","-",")","-menthyl","beta-D-glucoside","+","H","(","+",")","+","UDP","."),4366460). assertion_content_comment('oboGo_MonoterpenolOAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","a","monoterpenol","=","CoA","+","a","monoterpenol","acetate","ester","."),4271948). assertion_content_comment('oboGo_MonoterpenylDiphosphataseactivity',s("Catalysis","of","the","reaction",":","monoterpenyl","diphosphate","+","H2O","=","monoterpenol","+","diphosphate","."),4271959). assertion_content_comment('oboGo_Morphine6Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","morphine","+","NAD","(","P",")","+","=","morphinone","+","NAD","(","P",")","H","+","H","+"),4271936). assertion_content_comment('oboGo_MPP7Dlg1Lin7complex',s("A","heterotrimeric","protein","complex","formed","by","the","association","of","MMP7",",","DLG1","and","either","LIN7A","or","LIN7C",";","regulates","the","stability","and","localization","of","DLG1","to","cell","junctions","."),4073985). assertion_content_comment('oboGo_MRNA2OMethyladenosineN6Methyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","m","(","7",")","G","(","5","'",")","pppAm","=","S-adenosyl-L-homocysteine","+","m","(","7",")","G","(","5","'",")","pppm","(","6",")","Am","."),4304776). assertion_content_comment('oboGo_MRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","an","mRNA","molecule","."),3974346). assertion_content_comment('oboGo_MRNA3Utrbinding',s("Interacting","selectively","and","non-covalently","with","the","3","'","untranslated","region","of","an","mRNA","molecule","."),4192657). assertion_content_comment('oboGo_MRNA5Utrbinding',s("Interacting","selectively","and","non-covalently","with","the","5","'","untranslated","region","of","an","mRNA","molecule","."),4384477). assertion_content_comment('oboGo_MRNABindinghnrnpproteinimportintonucleus',s("The","directed","movement","of","a","heterogeneous","nuclear","ribonucleoprotein","from","the","cytoplasm","into","the","nucleus",",","across","the","nuclear","membrane","."),4230242). assertion_content_comment('oboGo_MRNAContainingribonucleoproteincomplexexportfromnucleus',s("The","directed","movement","of","a","ribonucleoprotein","complex","that","contains","messenger","RNA","from","the","nucleus","to","the","cytoplasm","."),4164239). assertion_content_comment('oboGo_MRNAGuanineN7Methyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","G","(","5","'",")","pppR-RNA","=","S-adenosyl-L-homocysteine","+","m7G","(","5","'",")","pppR-RNA",".","m7G","(","5","'",")","pppR-RNA","is","mRNA","containing","an","N7-methylguanine","cap",";","R","may","be","guanosine","or","adenosine","."),4206158). assertion_content_comment('oboGo_MRNAN6AdenosineMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","RRACH","=","S-adenosyl-L-homocysteine","+","RRm6ACH",";","R","is","a","purine",",","and","H","is","C",",","A",",","or","U","."),4383283). assertion_content_comment('oboGo_MRNANucleoside_2_O__MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","m7G","(","5","'",")","pppR-RNA","=","S-adenosyl-L-homocysteine","+","m7G","(","5","'",")","pppRm-RNA",".","R","may","be","guanosine","or","adenosine","."),4206144). assertion_content_comment('oboGo_MTORFkbp12Rapamycincomplex',s("A","protein","complex","that","contains","the","mTOR","(","mammalian","target","of","rapamycin",")","serine/threonine","kinase",",","the","peptidyl-prolyl","cis-trans","isomerase","FKBP12","(","FKBP1A",")","and","rapamycin","(","sirolimus",")"),4175292). assertion_content_comment('oboGo_MuconolactoneDeltaIsomeraseactivity',s("Catalysis","of","the","reaction",":","2",",","5-dihydro-5-oxofuran-2-acetate","=","3",",","4-dihydro-5-oxofuran-2-acetate","."),4303135). assertion_content_comment('oboGo_MucosalAssociatedlymphoidtissuedevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","mucosal-associated","lymphoid","tissue","over","time",",","from","its","formation","to","the","mature","structure",".","Mucosal-associated","lymphoid","tissue","is","typically","found","as","nodules","associated","with","mucosal","epithelia","with","distinct","internal","structures","including","B-","and","T-zones","for","the","activation","of","lymphocytes","."),4135598). assertion_content_comment('oboGo_MugineicAcid3Dioxygenaseactivity',s("Catalysis","of","the","reactions",":","mugineic","acid","+","2-oxoglutarate","+","O2","=","3-epihydroxymugineic","acid","+","succinate","+","CO2",",","and","2","'","-deoxymugineic","acid","+","2-oxoglutarate","+","O2","=","3-epihydroxy-2","'","-deoxymugineic","acid","+","succinate","+","CO2","."),4342690). assertion_content_comment('oboGo_MultiEifcomplex',s("A","multifactor","complex","composed","of","multiple","translation","initiation","factors","and","the","initiatior","tRNAiMet",",","which","is","ready","to","bind","to","the","small","(","40S",")","ribosome","to","form","the","43S","preinitiation","complex",".","In","S",".","cerevisiae",",","this","complex","is","composed","of","eIF1",",","eIF2",",","eIF3",",","and","eIF5","."),4325358). assertion_content_comment('oboGo_MultiLayerfolliclestage',s("The","stage","in","oogenesis","when","many","layers","of","follicle","cells","surround","the","oocyte",".","There","is","a","yolk","nucleus","(","Balbiani","'","s","Body",")","near","the","germinal","vesicle","."),3981855). assertion_content_comment('oboGo_MultiOrganismbiosyntheticprocess',s("Any","biosynthetic","process","-","chemical","reactions","and","pathways","resulting","in","the","formation","of","substances","-","which","involves","more","than","one","organism","."),4194802). assertion_content_comment('oboGo_MultiOrganismcarbohydratecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","carbohydrates",",","any","of","a","group","of","organic","compounds","based","of","the","general","formula","Cx","(","H2O",")","y",",","involving","more","than","one","organism","."),4109886). assertion_content_comment('oboGo_MultiOrganismcarbohydratemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","carbohydrates",",","any","of","a","group","of","organic","compounds","based","of","the","general","formula","Cx","(","H2O",")","y",",","that","involve","more","than","one","organism","."),4109881). assertion_content_comment('oboGo_MultiOrganismcatabolicprocess',s("Any","catabolic","process","-","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","substances","-","which","involves","more","than","one","organism","."),4109916). assertion_content_comment('oboGo_MultiOrganismcellwallmacromoleculemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","macromolecules","forming",",","or","destined","to","form",",","part","of","a","cell","wall",",","involving","more","than","one","organism",".","A","cell","wall","is","a","rigid","or","semi-rigid","envelope","lying","outside","the","cell","membrane","of","plant",",","fungal","and","most","prokaryotic","cells",",","maintaining","their","shape","and","protecting","them","from","osmotic","lysis","."),4109984). assertion_content_comment('oboGo_MultiOrganismglucanmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","glucans",",","polysaccharides","consisting","only","of","glucose","residues",",","involving","more","than","one","organism","."),4188371). assertion_content_comment('oboGo_MultiOrganismmetabolicprocess',s("Any","metabolic","process","-","chemical","reactions","and","pathways",",","including","anabolism","and","catabolism",",","by","which","living","organisms","transform","chemical","substances","-","which","involves","more","than","one","organism","."),4109876). assertion_content_comment('oboGo_MultiOrganismprocess',s("Any","process","in","which","an","organism","has","an","effect","on","another","organism","of","the","same","or","different","species","."),3977401). assertion_content_comment('oboGo_MultiOrganismsignaling',s("The","transfer","of","information","between","living","organisms","."),4347007). assertion_content_comment('oboGo_MultipleInositolPolyphosphatephosphataseactivity',s("Catalysis","of","the","reaction",":","myo-inositol","hexakisphosphate","+","H2O","=","myo-inositol","pentakisphosphate","(","mixed","isomers",")","+","phosphate","."),4207151). assertion_content_comment('oboGo_MultiSpeciesbiofilmformationinoronhostorganism',s("A","process","in","which","microorganisms","of","different","species","attach","to","and","grow","in","or","on","a","surface","in","a","host","species",",","and","produce","extracellular","polymers","that","facilitate","attachment","and","matrix","formation",",","resulting","in","an","alteration","in","the","phenotype","of","the","organisms","with","respect","to","growth","rate","and","gene","transcription",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4287678). assertion_content_comment('oboGo_MultiSpeciesbiofilmformationoninanimatesubstrate',s("A","process","in","which","microorganisms","of","different","species","attach","to","and","grow","on","an","inanimate","surface","such","as","a","rock","or","pipe","and","produce","extracellular","polymers","that","facilitate","attachment","and","matrix","formation",",","resulting","in","an","alteration","in","the","phenotype","of","the","organisms","with","respect","to","growth","rate","and","gene","transcription","."),4287688). assertion_content_comment('oboGo_MultiSpeciesbiofilmformation',s("A","process","in","which","microorganisms","of","different","species","attach","to","and","grow","on","a","surface","and","produce","extracellular","polymers","that","facilitate","attachment","and","matrix","formation",",","resulting","in","an","alteration","in","the","phenotype","of","the","organisms","with","respect","to","growth","rate","and","gene","transcription","."),4095281). assertion_content_comment('oboGo_MuOpioidreceptoractivity',s("Combining","with","an","opioid","to","initiate","a","change","in","cell","activity",",","with","the","pharmacological","characteristics","of","mu-opioid","receptors",",","including","high","affinity","for","enkephalins","and","beta-endorphin","but","low","affinity","for","dynorphins","."),4198913). assertion_content_comment('oboGo_MureinDDEndopeptidaseactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4248755). assertion_content_comment('oboGo_MureinSacculus_6',s("OBSOLETE",".","A","structure","formed","of","the","cross-linked","polymer","peptidoglycan","(","also","called","murein",")","that","forms","a","covalently","closed","net","around","a","bacterial","cell",",","and","imparts","structural","stability","to","the","bacterial","cell","wall","."),4306624). assertion_content_comment('oboGo_MuscleAlphaActininbinding',s("Interacting","selectively","and","non-covalently","with","muscle","isoforms","of","actinin",".","Muscle","alpha-actinin","isoforms","are","found","in","skeletal","and","cardiac","muscle","and","are","localized","to","the","Z-disc","."),4286076). assertion_content_comment('oboGo_MuTypeopioidreceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","mu-type","opioid","receptor","."),4324113). assertion_content_comment('oboGo_MXylenebiosyntheticprocess',s("OBSOLETE",".","The","chemical","reactions","and","pathways","resulting","in","the","formation","of","m-xylene",",","1",",","3-dimethylbenzene",",","a","colorless",",","liquid","aromatic","hydrocarbon","."),4353506). assertion_content_comment('oboGo_MXylenecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","m-xylene",",","1",",","3-dimethylbenzene",",","a","colorless",",","liquid","aromatic","hydrocarbon","."),4313724). assertion_content_comment('oboGo_MXylenemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","m-xylene",",","(","1",",","3-dimethylbenzene",")","a","colorless",",","liquid","aromatic","hydrocarbon","."),4272841). assertion_content_comment('oboGo_MycMaxcomplex',s("A","transcriptional","factor","complex","that","consists","of","a","heterodimer","of","the","bHLH-ZIP","proteins","Myc","and","Max","."),4168707). assertion_content_comment('oboGo_MycothiolDependentdetoxification',s("The","chemical","reactions","using","mycothiol","to","convert","an","alkylating","agent","to","an","S-conjugate","of","mycothiol",".","The","latter","is","cleaved","to","release","mercapturic","acid","which","is","excreted","from","the","cell","."),4334404). assertion_content_comment('oboGo_MycothiolDependentformaldehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","formaldehyde","+","mycothiol","+","NAD","+","=","S-formylmycothiol","+","NADH","+","H","+"),4278290). assertion_content_comment('oboGo_MyD88DependenttollLikereceptor2signalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","a","toll-like","2","receptor","where","the","MyD88","adaptor","molecule","mediates","transduction","of","the","signal",".","Toll-like","2","receptors","are","pattern","recognition","receptors","that","bind","microbial","pattern","motifs","to","initiate","an","innate","immune","response","."),4380070). assertion_content_comment('oboGo_MyD88DependenttollLikereceptor4signalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","a","toll-like","4","receptor",",","where","the","MyD88","adaptor","molecule","mediates","transduction","of","the","signal",".","Toll-like","4","receptors","bind","bacterial","lipopolysaccharide","(","LPS",")","to","initiate","an","innate","immune","response","."),4380175). assertion_content_comment('oboGo_MyD88DependenttollLikereceptorsignalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","a","toll-like","receptor","where","the","MyD88","adaptor","molecule","mediates","transduction","of","the","signal",".","Toll-like","receptors","directly","bind","pattern","motifs","from","a","variety","of","microbial","sources","to","initiate","innate","immune","response","."),4076849). assertion_content_comment('oboGo_MyD88IndependenttollLikereceptorsignalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","a","toll-like","receptor","not","relying","on","the","MyD88","adaptor","molecule",".","Toll-like","receptors","directly","bind","pattern","motifs","from","a","variety","of","microbial","sources","to","initiate","innate","immune","response","."),4076885). assertion_content_comment('oboGo_MyelinBasicProteinArgininenMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","(","myelin","basic","protein",")","-arginine","=","S-adenosyl-L-homocysteine","+","(","myelin","basic","protein",")","-N","(","omega",")","-methyl-arginine","."),4303666). assertion_content_comment('oboGo_MyelinProteolipidoPalmitoyltransferaseactivity',s("Catalysis","of","the","reaction",":","[","myelin","proteolipid","]","+","palmityl-CoA","=","[","myelin","proteolipid","]","O-palmitoylprotein","+","CoA","."),4365329). assertion_content_comment('oboGo_Myo2pVac17pVac8ptransportcomplex',s("A","protein","complex","that","is","involved","in","transport","of","vacuoles","to","a","newly","formed","daughter","cell",".","In","yeast",",","this","complex","is","composed","of","Myo2p",",","Vac17p",",","and","Vac8p","."),4171209). assertion_content_comment('oboGo_MyoInositolhexakisphosphatebiosyntheticprocesslipidDependent',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1D-myo-inositol","1",",","2",",","3",",","4",",","5",",","6-hexakisphosphate",",","phytate",",","by","a","pathway","using","inositol","1",",","4",",","5-trisphosphate","produced","from","phosphatidylinositol","4",",","5-biphosphate","hydrolysis","by","phospholipase","C","."),4340915). assertion_content_comment('oboGo_MyoInositolhexakisphosphatebiosyntheticprocesslipidIndependent',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","phytic","acid",",","myo-inositol","hexakisphosphate",",","by","the","successively","phosphorylation","of","myo-inositol","or","an","inositol","trisphosphate",";","the","inositol","trisphosphates","that","may","be","used","by","this","pathway","are","inositol","3",",","4",",","5-trisphosphate","and","inositol","3",",","4",",","6trisphosphate","."),4341047). assertion_content_comment('oboGo_MyoInositolhexakisphosphatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","phytic","acid",",","myo-inositol","hexakisphosphate",",","a","regulator","of","intracellular","signaling",",","a","highly","abundant","animal","anti-nutrient","and","a","phosphate","and","mineral","storage","compound","in","plant","seeds","."),4335341). assertion_content_comment('oboGo_MyoInositolhexakisphosphatebiosyntheticprocessviadirectphosphorylationofinositol145Trisphosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1D","myo-inositol","1",",","2",",","3",",","4",",","5",",","6-hexakisphosphate",",","phytate",",","by","a","pathway","using","inositol","1",",","4",",","5-trisphosphate","produced","from","phosphatidylinositol","4",",","5-biphosphate","hydrolysis","by","phospholipase","C",";","in","this","pathway",",","inositol","1",",","4",",","5-trisphosphate","is","successively","phosphorylated","to","yield","inositol","hexakisphosphate","."),4341077). assertion_content_comment('oboGo_MyoInositolhexakisphosphatebiosyntheticprocessviainositol134Trisphosphate',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","1D-myo-inositol","1",",","2",",","3",",","4",",","5",",","6-hexakisphosphate",",","phytate",",","by","a","pathway","using","inositol","1",",","4",",","5-trisphosphate","produced","from","phosphatidylinositol","4",",","5-biphosphate","hydrolysis","by","phospholipase","C",";","in","this","pathway",",","inositol","1",",","4",",","5-trisphosphate","is","first","converted","to","inositol","1",",","3",",","4-trisphosphate",",","and","then","phosphorylated","further","."),4341062). assertion_content_comment('oboGo_MyoInositolhexakisphosphatedephosphorylation',s("The","process","of","removing","one","or","more","phosphate","group","from","myo-inositol","hexakisphosphate","."),4340779). assertion_content_comment('oboGo_MyoInositolhexakisphosphatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","phytic","acid",",","myo-inositol","hexakisphosphate",",","a","regulator","of","intracellular","signaling",",","a","highly","abundant","animal","anti-nutrient","and","a","phosphate","and","mineral","storage","compound","in","plant","seeds","."),4335336). assertion_content_comment('oboGo_MyoInositolhexakisphosphatetransport',s("The","directed","movement","of","myo-inositol","hexakisphosphate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4337763). assertion_content_comment('oboGo_MyoInositol_Hydrogensymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","myo-inositol","(","out",")","+","H","+","(","out",")","=","myo-inositol","(","in",")","+","H","+","(","in",")"),4216666). assertion_content_comment('oboGo_MyoInositolphosphatetransport',s("The","directed","movement","of","any","phosphorylated","myo-inositol","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4337754). assertion_content_comment('oboGo_MyoInositol_Sodiumsymporteractivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","myo-inositol","(","out",")","+","Na","+","(","out",")","=","myo-inositol","(","in",")","+","Na","+","(","in",")"),4216566). assertion_content_comment('oboGo_MyoInositoltransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","myo-inositol","from","one","side","of","the","membrane","to","the","other",".","Myo-inositol","is","1",",","2",",","3",",","4",",","5/4",",","6-cyclohexanehexol",",","a","growth","factor","for","animals","and","microorganisms","."),4216562). assertion_content_comment('oboGo_MyoInositoltransport',s("The","directed","movement","of","myo-inositol","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Myo-inositol","is","1",",","2",",","3",",","4",",","5/4",",","6-cyclohexanehexol",",","a","growth","factor","for","animals","and","microorganisms","."),4290970). assertion_content_comment('oboGo_Myo_Inosose_2DehydrataseActivity',s("Catalysis","of","the","reaction",":","2",",","4",",","6/3",",","5-pentahydroxycyclohexanone","=","3D-3",",","5/4-trihydroxycyclohexane-1",",","2-dione","+","H","(","2",")","O","."),4271833). assertion_content_comment('oboGo_MyosinLightChainPhosphataseactivity',s("Catalysis","of","the","reaction",":","myosin","light-chain","phosphate","+","H2O","=","myosin","light","chain","+","phosphate","."),4271846). assertion_content_comment('oboGo_MyrceneEBetaOcimenesynthaseactivity',s("OBSOLETE",".","Catalysis","of","the","conversion","of","geranyl","diphosphate","(","GPP",")","into","the","acyclic","monoterpenes","beta-myrcene",",","(","E",")","-beta-ocimene",",","and","other","minor","cyclic","monoterpenes","."),4312316). assertion_content_comment('oboGo_Myricetin3OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","+","myricetin","=","S-adenosyl-L-homocysteine","+","laricitrin","."),4342267). assertion_content_comment('oboGo_MyristoylAcylCarrierProteinhydrolaseactivity',s("Catalysis","of","the","reaction",":","myristoyl-","[","acyl-carrier","protein","]","+","H2O","=","[","acyl-carrier","protein","]","+","myristate","."),4304664). assertion_content_comment('oboGo_MyristoylCoa11Edesaturaseactivity',s("Catalysis","of","the","reaction",":","myristoyl-CoA","+","NAD","(","P",")","H","+","H","+","+","O2","=","(","E",")","-11-tetradecenoyl-CoA","+","NAD","(","P",")","+","+","2","H2O","."),4278226). assertion_content_comment('oboGo_MyristoylCoa11Zdesaturaseactivity',s("Catalysis","of","the","reaction",":","myristoyl-CoA","+","NAD","(","P",")","H","+","H","+","+","O2","=","(","Z",")","-11-tetradecenoyl-CoA","+","NAD","(","P",")","+","+","2","H2O","."),4278215). assertion_content_comment('oboGo_N_1_NaphthylphthalamicAcidBinding',s("Interacting","selectively","and","non-covalently","with","N-1-naphthylphthalamic","acid",",","an","auxin","transport","inhibitor","."),4329952). assertion_content_comment('oboGo_N2_2_CarboxyethylArginineSynthaseActivity',s("Catalysis","of","the","reaction",":","D-glyceraldehyde","3-phosphate","+","L-arginine","=","N","(","2",")","-","(","2-carboxyethyl",")","-L-arginine","+","H","(","+",")","+","phosphate","."),4343873). assertion_content_comment('oboGo_N2AcetylLAminoadipatekinaseactivity',s("Catalysis","of","the","reaction",":","N2-acetyl-L-aminoadipate","+","ATP","=","N2-acetyl-L-aminoadipyl-delta-phosphate","+","ADP","."),4326016). assertion_content_comment('oboGo_N2AcetylLAminoadipatesemialdehydedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N2-acetyl-L-aminoadipyl-delta-phosphate","+","NADPH","+","H","+","=","N2-acetyl-L-aminoadipate","semialdehyde","+","NADP","+","+","orthophosphate","."),4326005). assertion_content_comment('oboGo_N2AcetylLLysineaminotransferaseactivity',s("Catalysis","of","the","reaction",":","N2-acetyl-L-aminoadipate","semialdehyde","+","L-glutamate","=","2-oxoglutarate","+","N2-acetyl-L-lysine","."),4325994). assertion_content_comment('oboGo_N2AcetylLLysinedeacetylaseactivity',s("Catalysis","of","the","reaction",":","N2-acetyl-L-lysine","+","H2O","=","acetate","+","L-lysine","."),4326060). assertion_content_comment('oboGo_N2AcetylLOrnithine_2Oxoglutarate5Aminotransferaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","N","(","2",")","-acetyl-L-ornithine","=","N-acetyl-L-glutamate","5-semialdehyde","+","L-glutamate","."),4186201). assertion_content_comment('oboGo_N4BetaNAcetylglucosaminylLAsparaginaseactivity',s("Catalysis","of","the","reaction",":","N","(","4",")","-","(","beta-N-acetyl-D-glucosaminyl",")","-L-asparagine","+","H","(","2",")","O","=","N-acetyl-beta-D-glucosaminylamine","+","L-aspartate","+","H","(","+",")"),4184765). assertion_content_comment('oboGo_N_4MethylationOfCytosine',s("The","covalent","transfer","of","a","methyl","group","to","N-4","of","cytosine","in","a","DNA","molecule","."),4154716). assertion_content_comment('oboGo_N_5_Amino_5_Carboxypentanoyl_L_Cysteinyl_D_ValineSynthaseActivity',s("Catalysis","of","the","reaction",":","L-2-aminoadipate","+","L-cysteine","+","L-valine","+","3","ATP","+","H","(","2",")","O","=","N-","[","(","5S",")","-5-amino-5-carboxypentanoyl","]","-L-cysteinyl-D-valine","+","3","AMP","+","3","diphosphate","+","6","H","(","+",")"),4268359). assertion_content_comment('oboGo_N5Carboxyethylornithinesynthaseactivity',s("Catalysis","of","the","reaction",":","N","(","5",")","-","[","1","(","S",")","-1-carboxyethyl","]","-L-ornithine","+","H","(","2",")","O","+","NADP","(","+",")","=","L-ornithine","+","H","(","+",")","+","NADPH","+","pyruvate","."),4365802). assertion_content_comment('oboGo_N5N10Methenyltetrahydromethanopterinhydrogenaseactivity',s("Catalysis","of","the","reaction",":","5",",","10-methenyl-5",",","6",",","7",",","8-tetrahydromethanopterin","+","H","(","2",")","=","5",",","10-methylenetetrahydromethanopterin","+","H","(","+",")"),4364694). assertion_content_comment('oboGo_N6_12_DicarboxyethylAMPAMP_LyaseFumarate_FormingActivity',s("Catalysis","of","the","reaction",":","N6-","(","1",",","2-dicarboxyethyl",")","AMP","=","fumarate","+","AMP","."),4213032). assertion_content_comment('oboGo_N6AcetylBetaLysinetransaminaseactivity',s("Catalysis","of","the","reaction",":","2-oxoglutarate","+","3-amino-6-acetamidohexanoate","=","L-glutamate","+","3-oxo-6-acetamidohexanoate","."),4368906). assertion_content_comment('oboGo_N6HydroxylysineoAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","6",")","-hydroxy-L-lysine","+","acetyl-CoA","=","N","(","6",")","-acetyl-N","(","6",")","-hydroxy-L-lysine","+","CoA","."),4271627). assertion_content_comment('oboGo_N6Isopentenyladenosinemethylthiotransferaseactivity',s("Catalysis","of","the","methylthiolation","(","-SCH3","addition",")","at","the","C2","of","the","adenosine","ring","of","N6-isopentenyladenosine","(","i6A",")","in","tRNA",",","to","form","2-methylthio-N6-isopentenyladenosine","(","ms2i6A",")"),4379301). assertion_content_comment('oboGo_N6MethylLysineoxidaseactivity',s("Catalysis","of","the","reaction",":","N","(","6",")","-methyl-L-lysine","+","H","(","2",")","O","+","O","(","2",")","=","L-lysine","+","formaldehyde","+","H","(","2",")","O","(","2",")"),4271596). assertion_content_comment('oboGo_N6Threonylcarbomyladenosinemethylthiotransferaseactivity',s("Catalysis","of","the","methylthiolation","(","-SCH3","addition",")","at","the","C2","of","the","adenosine","ring","of","N6-threonylcarbomyladenosine","(","t6A",")","in","tRNA",",","to","form","2-methylthio-N6-threonylcarbamoyladenosine","(","ms2t6A",")"),4379311). assertion_content_comment('oboGo_NAADPSensitivecalciumReleasechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","calcium","ion","by","a","channel","that","opens","when","nicotinic","acid","adenine","dinucleotide","phosphate","(","NAADP",")","has","been","bound","by","the","channel","complex","or","one","of","its","constituent","parts","."),4158436). assertion_content_comment('oboGo_NAcetylaminoadipatekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","N-acetyl-L-aminoadipate","=","ADP","+","N-acetyl-L-aminoadipate","5-phosphate","."),4326687). assertion_content_comment('oboGo_NAcetylAnhydromuramoylLAlanineamidaseactivity',s("Catalysis","of","the","reaction",":","GlcNAc-1",",","6-anhMurNAc-L-Ala-gamma-D-Glu-DAP-D-Ala","+","H2O","glcNAc-1",",","6-anhMurNAc","+","L-Ala-gamma-D-Glu-DAP-D-Ala","."),4260307). assertion_content_comment('oboGo_NAcetylBetaAlaninedeacetylaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-beta-alanine","+","H","(","2",")","O","=","beta-alanine","+","acetate","."),4271874). assertion_content_comment('oboGo_NAcetylBetaGlucosaminylGlycoprotein4BetaNAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-galactosamine","+","N-acetyl-beta-D-glucosaminyl","group","=","UDP","+","N-acetyl-beta-D-galactosaminyl-","(","1-","&","gt",";","4",")","-N-acetyl-beta-D-glucosaminyl","group","."),4343287). assertion_content_comment('oboGo_NAcetylcitrullinedeacetylaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-L-citrulline","+","H2O","=","citrulline","+","acetate","."),4328742). assertion_content_comment('oboGo_NAcetyldiaminopimelatedeacetylaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-LL-2",",","6-diaminopimelate","+","H","(","2",")","O","=","LL-2",",","6-diaminopimelate","+","acetate","."),4271886). assertion_content_comment('oboGo_NAcetylgalactosamine4OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","N-acetyl-D-galactosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","N-acetyl-D-galactosamine","4-sulfate","."),4361605). assertion_content_comment('oboGo_N_Acetylgalactosamine_4_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","4-sulfate","groups","of","the","N-acetyl-D-galactosamine","4-sulfate","units","of","chondroitin","sulfate","and","dermatan","sulfate","."),4185800). assertion_content_comment('oboGo_NAcetylgalactosamine4Sulfate6OSulfotransferaseactivity',s("Catalysis","of","the","reactions",":","3","'","-phosphoadenylyl","sulfate","+","dermatan","=","adenosine","3","'",",","5","'","-bisphosphate","+","dermatan","6","'","-sulfate","and","3","'","-phosphoadenylyl","sulfate","+","chondroitin","=","adenosine","3","'",",","5","'","-bisphosphate","+","chondroitin","6","'","-sulfate","."),4277596). assertion_content_comment('oboGo_N_Acetylgalactosamine_6_PhosphateDeacetylaseActivity',s("Catalysis","of","the","reaction",":","H2O","+","N-acetyl-D-galactosamine","6-phosphate","=","acetate","+","D-galactosamine","6-phosphate","."),4369840). assertion_content_comment('oboGo_N_Acetylgalactosamine_6_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","6-sulfate","groups","of","the","N-acetyl-D-galactosamine","6-sulfate","units","of","chondroitin","sulfate","and","of","the","D-galactose","6-sulfate","units","of","keratan","sulfate","."),4328754). assertion_content_comment('oboGo_NAcetylgalactosaminebinding',s("Interacting","selectively","and","non-covalently","with","N-acetylgalactosamine",",","2-acetamido-2-deoxygalactopyranose",",","the","n-acetyl","derivative","of","galactosamine","."),4218850). assertion_content_comment('oboGo_NAcetylgalactosaminekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","N-acetyl-D-galactosamine","=","ADP","+","N-acetyl-alpha-D-galactosamine","1-phosphate","."),4343719). assertion_content_comment('oboGo_NAcetylgalactosaminelectin',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4218854). assertion_content_comment('oboGo_NAcetylgalactosaminetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","N-acetylgalactosamine","from","one","side","of","the","membrane","to","the","other",".","N-acetylgalactosamine",",","2-acetamido-2-deoxygalactopyranose",",","is","the","n-acetyl","derivative","of","galactosamine","."),4293551). assertion_content_comment('oboGo_NAcetylgalactosaminetransport',s("The","directed","movement","of","N-acetylgalactosamine","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","N-acetylgalactosamine",",","2-acetamido-2-deoxygalactopyranose",",","is","the","n-acetyl","derivative","of","galactosamine","."),4291171). assertion_content_comment('oboGo_NAcetylgalactosaminoglycandeacetylaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","N-acetyl-D-galactosaminoglycan","=","acetate","+","D-galactosaminoglycan","."),4368774). assertion_content_comment('oboGo_NAcetylgalactosaminylProteoglycan3BetaGlucuronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-beta-D-galactosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-proteoglycan","+","UDP-alpha-D-glucuronate","=","beta-D-glucuronosyl-","(","1",",","3",")","-N-acetyl-beta-D-galactosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-proteoglycan","+","UDP","."),4269140). assertion_content_comment('oboGo_NAcetylGammaAminoadipylPhosphatereductaseactivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-acetyl-L-aminoadipate-semialdehyde","+","NADP","+","+","phosphate","=","N","(","2",")","-acetyl-L-gamma-aminoadipyl","phosphate","+","NADPH","."),4326561). assertion_content_comment('oboGo_NAcetylGammaGlutamylPhosphatereductaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-L-glutamate","5-semialdehyde","+","NADP","+","+","phosphate","=","N-acetyl-5-glutamyl","phosphate","+","NADPH","+","H","+"),4185816). assertion_content_comment('oboGo_N_Acetylglucosamine_1_PhosphodiesterAlpha_N_AcetylglucosaminidaseActivity',s("Catalysis","of","the","reaction",":","glycoprotein","N-acetyl-D-glucosaminyl-phospho-D-mannose","+","H2O","=","N-acetyl-D-glucosamine","+","glycoprotein","phospho-D-mannose","."),4185772). assertion_content_comment('oboGo_NAcetylglucosamine6OSulfotransferaseactivity',s("Catalysis","of","the","reaction",":","3","'","-phosphoadenosine","5","'","-phosphosulfate","+","N-acetyl-D-glucosamine","=","adenosine","3","'",",","5","'","-bisphosphate","+","N-acetyl-D-glucosamine","6-sulfate","."),4361510). assertion_content_comment('oboGo_N_Acetylglucosamine_6_PhosphateDeacetylaseActivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosamine","6-phosphate","+","H2O","=","D-glucosamine","6-phosphate","+","acetate","."),4253852). assertion_content_comment('oboGo_N_Acetylglucosamine_6_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","6-sulfate","group","of","the","N-acetyl-D-glucosamine","6-sulfate","units","of","heparan","sulfate","and","keratan","sulfate","."),4253866). assertion_content_comment('oboGo_NAcetylglucosaminebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","N-acetylglucosamine",".","The","D","isomer","is","a","common","structural","unit","of","glycoproteins","in","plants",",","bacteria","and","animals",";","it","is","often","the","terminal","sugar","of","an","oligosaccharide","group","of","a","glycoprotein","."),4084265). assertion_content_comment('oboGo_NAcetylglucosaminecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","N-acetylglucosamine",".","The","D","isomer","is","a","common","structural","unit","of","glycoproteins","in","plants",",","bacteria","and","animals",";","it","is","often","the","terminal","sugar","of","an","oligosaccharide","group","of","a","glycoprotein","."),4224614). assertion_content_comment('oboGo_NAcetylglucosaminedeacetylaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosamine","+","H","(","2",")","O","=","D-glucosamine","+","acetate","."),4271900). assertion_content_comment('oboGo_NAcetylglucosaminekinaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosamine","+","ATP","=","N-acetyl-D-glucosamine","6-phosphate","+","ADP","+","2","H","(","+",")"),4300125). assertion_content_comment('oboGo_NAcetylglucosaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-acetylglucosamine",".","The","D","isomer","is","a","common","structural","unit","of","glycoproteins","in","plants",",","bacteria","and","animals",";","it","is","often","the","terminal","sugar","of","an","oligosaccharide","group","of","a","glycoprotein","."),4084262). assertion_content_comment('oboGo_NAcetylglucosaminetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","N-acetylglucosamine","from","one","side","of","the","membrane","to","the","other",".","The","D","isomer","of","N-acetylglucosamine","is","a","common","structural","unit","of","glycoproteins","in","plants",",","bacteria","and","animals",";","it","is","often","the","terminal","sugar","of","an","oligosaccharide","group","of","a","glycoprotein","."),4293535). assertion_content_comment('oboGo_NAcetylglucosaminetransport',s("The","directed","movement","of","N-acetylglucosamine","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4291141). assertion_content_comment('oboGo_NAcetylglucosaminyldiphosphodolicholnAcetylglucosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","N-acetyl-D-glucosaminyl-diphosphodolichol","=","UDP","+","N",",","N","'","'","-diacetylchitobiosyldiphosphodolichol","."),4204304). assertion_content_comment('oboGo_NAcetylglucosaminyldiphosphoundecaprenolglucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosaminyldiphosphoundecaprenol","+","UDP-D-glucose","=","beta-D-glucosyl-1",",","4-N-acetyl-D-glucosaminyldiphosphoundecaprenol","+","UDP","."),4366775). assertion_content_comment('oboGo_NAcetylglucosaminyldiphosphoundecaprenolnAcetylBetaDMannosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosaminyldiphosphoundecaprenol","+","UDP-N-acetyl-D-mannosamine","=","N-acetyl-beta-D-mannosaminyl-1",",","4-N-acetyl-D-glucosaminyldiphosphoundecaprenol","+","UDP","."),4366790). assertion_content_comment('oboGo_NAcetylglucosaminylinositoldeacetylaseactivity',s("Catalysis","of","the","reaction",":","1D-myo-inositol","2-acetamido-2-deoxy-alpha-D-glucopyranoside","+","H2O","=","1D-myo-inositol","2-amino-2-deoxy-alpha-D-glucopyranoside","+","acetate",".","This","reaction","is","the","hydrolysis","of","an","acetyl","group","from","N-acetylglucosaminylinositol","."),4379280). assertion_content_comment('oboGo_NAcetylglucosaminylphosphatidylinositoldeacetylaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosaminylphosphatidylinositol","+","H2O","=","D-glucosaminylphosphatidylinositol","+","acetate",".","This","reaction","is","the","second","step","of","the","biosynthesis","of","glycosylphosphatidylinositol","(","GPI",")",",","used","to","anchor","various","eukaryotic","proteins","to","the","cell-surface","membrane","."),4346263). assertion_content_comment('oboGo_NAcetylglucosaminylProteoglycan4BetaGlucuronosyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-alpha-D-glucosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-proteoglycan","+","UDP-alpha-D-glucuronate","=","beta-D-glucuronosyl-","(","1",",","4",")","-N-acetyl-alpha-D-glucosaminyl-","(","1",",","4",")","-beta-D-glucuronosyl-proteoglycan","+","UDP","."),4269610). assertion_content_comment('oboGo_NAcetylhexosamine1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosamine","+","H","(","2",")","O","+","NAD","(","+",")","=","N-acetyl-D-glucosaminate","+","2","H","(","+",")","+","NADH","."),4271769). assertion_content_comment('oboGo_N_AcetyllactosamineBeta_13_GlucuronosyltransferaseActivity',s("Catalysis","of","the","transfer",",","in","a","beta","1",",","3","linkage",",","of","D-glucuronic","acid","(","GlcUA",")","from","UDP-GlcUA","to","N-acetyllactosamine","(","galactosyl","beta-1",",","4-N-acetylglucosamine",")"),4361774). assertion_content_comment('oboGo_NAcetyllactosaminesynthaseactivity',s("Catalysis","of","the","reaction",":","UDP-galactose","+","N-acetyl-D-glucosamine","=","UDP","+","N-acetyllactosamine","."),4184677). assertion_content_comment('oboGo_NAcetyllactosaminide3AlphaGalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","beta-D-galactosyl-","(","1",",","4",")","-beta-N-acetyl-D-glucosaminyl-R","+","UDP-galactose","=","alpha-D-galactosyl-","(","1",",","3",")","-beta-D-galactosyl-","(","1",",","4",")","-beta-N-acetyl-D-glucosaminyl-R","+","UDP","."),4367435). assertion_content_comment('oboGo_N_AcetyllactosaminideAlpha_23_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-glycoprotein","=","CMP","+","alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-glycoprotein","."),4246348). assertion_content_comment('oboGo_N_AcetyllactosaminideBeta_13_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-R","=","UDP","+","N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-R","."),4254869). assertion_content_comment('oboGo_N_AcetyllactosaminideBeta_16_N_AcetylglucosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-glucosamine","+","beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-R","=","UDP","+","N-acetyl-beta-D-glucosaminyl-1",",","6-beta-D-galactosyl-1",",","4-N-acetyl-D-glucosaminyl-R","."),4246409). assertion_content_comment('oboGo_NAcetylLAspartateLGlutamateligaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","N-acetyl-L-aspartate","+","L-glutamate","=","ADP","+","phosphate","+","N-acetylaspartyl-glutamate","."),4157510). assertion_content_comment('oboGo_NAcetylmannosaminebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","N-acetylmannosamine",",","the","acetylated","derivative","of","mannosamine",",","2-amino-2-deoxymannose","."),4224699). assertion_content_comment('oboGo_NAcetylmannosaminecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","N-acetylmannosamine",",","the","acetylated","derivative","of","mannosamine",",","2-amino-2-deoxymannose","."),4224670). assertion_content_comment('oboGo_NAcetylmannosaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-acetylmannosamine",",","the","acetylated","derivative","of","mannosamine",",","2-amino-2-deoxymannose","."),4224652). assertion_content_comment('oboGo_NAcetylmuramoylLAlanineamidaseactivity',s("Catalysis","of","the","hydrolysis","of","the","link","between","N-acetylmuramoyl","residues","and","L-amino","acid","residues","in","certain","bacterial","cell-wall","glycopeptides","."),4251400). assertion_content_comment('oboGo_NAcetylneuraminate4OAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetylneuraminate","+","acetyl-CoA","=","N-acetyl-4-O-acetylneuraminate","+","CoA","."),4366318). assertion_content_comment('oboGo_NAcetylneuraminate7Oor9OAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-acetylneuraminate","+","acetyl-CoA","=","N-acetyl-7-O","(","or","9-O",")","-acetylneuraminate","+","CoA","."),4366299). assertion_content_comment('oboGo_NAcetylneuraminatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","N-acetylneuraminate",",","the","anion","of","5-","(","acetylamino",")","-3",",","5-dideoxy-D-glycero-D-galacto-non-3-ulosonic","acid","."),4224737). assertion_content_comment('oboGo_NAcetylneuraminatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","N-acetylneuraminate",",","the","anion","of","5-","(","acetylamino",")","-3",",","5-dideoxy-D-glycero-D-galacto-non-3-ulosonic","acid","."),4238346). assertion_content_comment('oboGo_NAcetylneuraminatelyaseactivity',s("Catalysis","of","the","reaction",":","N-acetylneuraminate","=","N-acetyl-D-mannosamine","+","pyruvate","."),4251359). assertion_content_comment('oboGo_NAcetylneuraminatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-acetylneuraminate",",","the","anion","of","5-","(","acetylamino",")","-3",",","5-dideoxy-D-glycero-D-galacto-non-3-ulosonic","acid","."),4224731). assertion_content_comment('oboGo_NAcetylneuraminatesynthaseactivity',s("Catalysis","of","the","reaction",":","phosphoenolpyruvate","+","N-acetyl-D-mannosamine","+","H2O","=","phosphate","+","N-acetylneuraminate","."),4265993). assertion_content_comment('oboGo_N_AcetylneuraminylgalactosylglucosylceramideBeta_14_N_AcetylgalactosaminyltransferaseActivity',s("Catalysis","of","the","reaction",":","N-acetylneuraminyl-2",",","3-alpha-D-galactosyl-1",",","4-beta-D-glucosylceramide","+","UDP-N-acetylgalactosamine","=","N-acetyl-beta-D-galactosaminyl-1",",","4-","(","N-acetyl-alpha-neuraminyl-2",",","3",")","-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","+","UDP","."),4366972). assertion_content_comment('oboGo_NAcetylneuraminylGalactosylglucosylceramidenAcetylgalactosaminyltransferaseactivity',s("Catalysis","of","the","reaction",":","UDP-N-acetyl-D-galactosamine","+","(","N-acetylneuraminyl",")","-D-galactosyl-D-glucosylceramide","=","UDP","+","N-acetyl-D-galactosaminyl-","(","N-acetylneuraminyl",")","-D-galactosyl-D-glucosylceramide","."),4184723). assertion_content_comment('oboGo_NAcetylornithinecarbamoyltransferaseactivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-acetyl-L-ornithine","+","carbamoyl","phosphate","=","N","(","2",")","-acetyl-L-citrulline","+","H","(","+",")","+","phosphate","."),4327029). assertion_content_comment('oboGo_NAcetyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acetyl","group","to","a","nitrogen","atom","on","the","acceptor","molecule","."),4204018). assertion_content_comment('oboGo_NAcylDAminoAciddeacylaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","N-acyl-D-amino","acid","=","D-amino","acid","+","an","acid","."),4369956). assertion_content_comment('oboGo_NAcylDAspartatedeacylaseactivity',s("Catalysis","of","the","reaction",":","N-acyl-D-aspartate","+","H","(","2",")","O","=","D-aspartate","+","a","carboxylate","."),4369934). assertion_content_comment('oboGo_NAcylDGlutamatedeacylaseactivity',s("Catalysis","of","the","reaction",":","N-acyl-D-glutamate","+","H","(","2",")","O","=","D-glutamate","+","a","carboxylate","."),4369945). assertion_content_comment('oboGo_NAcylethanolaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-acylethanolamines",".","An","N-acylethanolamine","is","an","ethanolamine","substituted","at","nitrogen","by","an","acyl","group","."),4174131). assertion_content_comment('oboGo_NAcylglucosamine2Epimeraseactivity',s("Catalysis","of","the","reaction",":","N-acyl-D-glucosamine","=","N-acyl-D-mannosamine","."),4271794). assertion_content_comment('oboGo_N_Acylglucosamine_6_Phosphate2_EpimeraseActivity',s("Catalysis","of","the","reaction",":","N-acyl-D-glucosamine","6-phosphate","=","N-acyl-D-mannosamine","6-phosphate","."),4369494). assertion_content_comment('oboGo_NAcylhexosamineoxidaseactivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-glucosamine","+","H","(","2",")","O","+","O","(","2",")","=","N-acetyl-D-glucosaminate","+","H","(","2",")","O","(","2",")","+","H","(","+",")"),4271781). assertion_content_comment('oboGo_NAcylmannosamine1Dehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N-acyl-D-mannosamine","+","NAD","(","+",")","=","N-acyl-D-mannosaminolactone","+","H","(","+",")","+","NADH","."),4271700). assertion_content_comment('oboGo_N_Acylmannosamine_6_Phosphate2_EpimeraseActivity',s("Catalysis","of","the","reaction",":","N-acetyl-D-mannosamine-6-phosphate","=","N-acetyl-D-glucosamine-6-phosphate","."),4259955). assertion_content_comment('oboGo_NAcylmannosaminekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","N-acyl-D-mannosamine","=","ADP","+","N-acyl-D-mannosamine","6-phosphate","."),4259977). assertion_content_comment('oboGo_N_Acylneuraminate_9_PhosphataseActivity',s("Catalysis","of","the","reaction",":","N-acylneuraminate","9-phosphate","+","H2O","=","N-acylneuraminate","+","phosphate","."),4271714). assertion_content_comment('oboGo_N_Acylneuraminate_9_PhosphateSynthaseActivity',s("Catalysis","of","the","reaction",":","H2O","+","phosphoenolpyruvate","+","N-acyl-D-mannosamine","6-phosphate","=","phosphate","+","N-acylneuraminate","9-phosphate","."),4370156). assertion_content_comment('oboGo_NAcylneuraminatecytidylyltransferaseactivity',s("Catalysis","of","the","reaction",":","CTP","+","N-acylneuraminate","=","diphosphate","+","CMP-N-acylneuraminate","."),4249057). assertion_content_comment('oboGo_NAcylphosphatidylethanolaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-acylphosphatidylethanolamines",".","An","N-acylphosphatidylethanolamine","is","a","phosphatidylethanolamine","substituted","at","nitrogen","by","an","acyl","group","."),4174155). assertion_content_comment('oboGo_NAcylsphingosinegalactosyltransferaseactivity',s("Catalysis","of","the","reaction",":","ceramide","+","UDP-galactose","=","D-galactosylceramide","+","UDP","."),4367063). assertion_content_comment('oboGo_NAcyltransferaseactivity',s("Catalysis","of","the","transfer","of","an","acyl","group","to","a","nitrogen","atom","on","the","acceptor","molecule","."),4182536). assertion_content_comment('oboGo_NADADPRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","+","+","(","ADP-D-ribosyl",")","(","n",")","-acceptor","=","nicotinamide","+","(","ADP-D-ribosyl",")","(","n","+","1",")","-acceptor","."),4184521). assertion_content_comment('oboGo_NADBinding_6',s("Interacting","selectively","and","non-covalently","with","nicotinamide","adenine","dinucleotide",",","a","coenzyme","involved","in","many","redox","and","biosynthetic","reactions",";","binding","may","be","to","either","the","oxidized","form",",","NAD","+",",","or","the","reduced","form",",","NADH","."),4175630). assertion_content_comment('oboGo_NADDependenthistonedeacetylaseactivityh3K14specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-acetyl-L-lysine","(","position","14",")","+","H2O","=","histone","H3","L-lysine","(","position","14",")","+","acetate",".","This","reaction","requires","the","presence","of","NAD",",","and","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","14","of","the","histone","H3","protein","."),4330198). assertion_content_comment('oboGo_NADDependenthistonedeacetylaseactivityh3K9specific',s("Catalysis","of","the","reaction",":","histone","H3","N6-acetyl-L-lysine","(","position","9",")","+","H2O","=","histone","H3","L-lysine","(","position","9",")","+","acetate",".","This","reaction","requires","the","presence","of","NAD",",","and","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","9","of","the","histone","H3","protein","."),4361875). assertion_content_comment('oboGo_NADDependenthistonedeacetylaseactivityh4K16specific',s("Catalysis","of","the","reaction",":","histone","H4","N6-acetyl-L-lysine","(","position","16",")","+","H2O","=","histone","H4","L-lysine","(","position","16",")","+","acetate",".","This","reaction","requires","the","presence","of","NAD",",","and","represents","the","removal","of","an","acetyl","group","from","lysine","at","position","16","of","the","histone","H4","protein","."),4361865). assertion_content_comment('oboGo_NADDependenthistonedeacetylaseactivity',s("Catalysis","of","the","reaction",":","histone","N6-acetyl-L-lysine","+","H2O","=","histone","L-lysine","+","acetate",".","This","reaction","requires","the","presence","of","NAD",",","and","represents","the","removal","of","an","acetyl","group","from","a","histone","."),4258002). assertion_content_comment('oboGo_NADDependentproteindeacetylaseactivity',s("Catalysis","of","the","removal","of","one","or","more","acetyl","groups","from","a","protein",",","requiring","NAD","."),4258000). assertion_content_comment('oboGo_NADDinitrogenReductaseadpDRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","+","+","[","dinitrogen","reductase","]","=","nicotinamide","+","ADP-D-ribosyl-","[","dinitrogen","reductase","]"),4309285). assertion_content_comment('oboGo_NADDiphthamideadpRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","peptide","diphthamide","+","NAD","+","=","peptide","N-","(","ADP-D-ribosyl",")","diphthamide","+","niacinamide","."),4367321). assertion_content_comment('oboGo_NADDNAADPRibosyltransferaseactivity',s("Catalysis","of","the","transfer","of","the","ADP-ribose","group","of","NAD","+","to","the","amino","group","at","N2","of","2","'","-deoxyguanosine","to","yield","N2-","(","alpha-ADP-ribos-1-yl",")","-2","'","-deoxyguanosine","and","its","beta","form","."),4307805). assertion_content_comment('oboGo_NADIndependenthistonedeacetylaseactivity',s("Catalysis","of","the","reaction",":","histone","N6-acetyl-L-lysine","+","H2O","=","histone","L-lysine","+","acetate",".","This","reaction","does","not","require","the","presence","of","NAD",",","and","represents","the","removal","of","an","acetyl","group","from","a","histone","."),4299929). assertion_content_comment('oboGo_NADMalicenzymec4photosynthesis',s("The","process","of","C4","photosynthesis",",","as","it","occurs","in","plants","in","which","the","enzyme","decarboxylating","C4","acids","in","the","bundle","sheath","is","NAD-malic","enzyme","."),4262777). assertion_content_comment('oboGo_NADPAsparagineadpRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","L-asparagine","=","nicotinamide","+","N2-","(","ADP-D-ribosyl",")","-L-asparagine","."),4284997). assertion_content_comment('oboGo_NADPBinding_2',s("Interacting","selectively","and","non-covalently","with","nicotinamide-adenine","dinucleotide","phosphate",",","a","coenzyme","involved","in","many","redox","and","biosynthetic","reactions",";","binding","may","be","to","either","the","oxidized","form",",","NADP","+",",","or","the","reduced","form",",","NADPH","."),4175591). assertion_content_comment('oboGo_NADPCysteineadpRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","L-cysteine","=","nicotinamide","+","N2-","(","ADP-D-ribosyl",")","-L-cysteine","."),4284160). assertion_content_comment('oboGo_NADPHAdrenodoxinreductaseactivity',s("Catalysis","of","the","reaction",":","oxidized","adrenodoxin","+","NADPH","+","H","+","=","reduced","adrenodoxin","+","NADP","+"),4297026). assertion_content_comment('oboGo_NADPHCytochromeC2reductaseactivity',s("Catalysis","of","the","reaction",":","NADPH","+","H","+","+","2","ferricytochrome","c2","=","NADP","+","+","2","ferrocytochrome","c2","."),4296978). assertion_content_comment('oboGo_NADPHDehydrogenaseQuinoneActivity_3',s("Catalysis","of","the","reaction",":","NADPH","+","H","+","+","acceptor","=","NADP","+","+","reduced","acceptor","."),4251551). assertion_content_comment('oboGo_NADPHHemoproteinreductaseactivity',s("Catalysis","of","the","reaction",":","NADPH","+","H","+","+","n","oxidized","hemoprotein","=","NADP","+","+","n","reduced","hemoprotein","."),4185233). assertion_content_comment('oboGo_NADPHOxidaseAssociatedcytochromeb558hydrogenchannelactivity',"OBSOLETE.",4295164). assertion_content_comment('oboGo_NADPMalicenzymec4photosynthesis',s("The","process","of","C4","photosynthesis",",","as","it","occurs","in","plants","in","which","the","enzyme","decarboxylating","C4","acids","in","the","bundle","sheath","is","NADP-malic","enzyme","."),4262749). assertion_content_comment('oboGo_NADPProteinArginineadpRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","L-arginine","=","nicotinamide","+","N2-","(","ADP-D-ribosyl",")","-L-arginine","."),4185300). assertion_content_comment('oboGo_NADPRetinoldehydrogenaseactivity',s("Catalysis","of","the","reaction",":","all-trans-retinol","+","NADP","+","=","all-trans-retinal","+","NADPH","+","H","+"),4191773). assertion_content_comment('oboGo_NADPSerineadpRibosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NAD","(","P",")","+","+","L-serine","=","nicotinamide","+","N2-","(","ADP-D-ribosyl",")","-L-serine","."),4284978). assertion_content_comment('oboGo_NADPTranshydrogenaseABSpecificactivity',s("Catalysis","of","the","reaction",":","NADPH","+","H","+","+","NAD","+","=","NADP","+","+","NADH","+","H","+","The","reaction","is","A-specific","(","i.e",".","the","pro-R","hydrogen","is","transferred","from","the","4-position","of","reduced","nicotinamide","cofactor",")","with","respect","to","NAD","+","and","B-specific","(","i.e",".","the","pro-S","hydrogen","is","transferred",")","with","respect","to","NADP","+"),4251573). assertion_content_comment('oboGo_NADPTranshydrogenaseBSpecificactivity',s("Catalysis","of","the","reaction",":","NADPH","+","H","+","+","NAD","+","=","NADP","+","+","NADH","+","H","+",",","driving","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other",".","In","the","course","of","the","reaction","(","left","to","right",")","one","H","atom","is","transferred","from","inside","the","cell","to","outside",".","The","reaction","is","B-specific","(","i.e",".","the","pro-S","hydrogen","is","transferred","from","the","4-position","of","reduced","nicotinamide","cofactor",")","with","respect","to","both","NAD","+","and","NADP","+"),4185364). assertion_content_comment('oboGo_NADPTranshydrogenaseComplexABSpecific',s("A","protein","complex","that","possesses","NAD","(","P",")","+","transhydrogenase","(","AB-specific",")","activity",".","Homodimeric",",","trimeric",",","and","heterotetrameric","complexes","have","been","identified","."),4259890). assertion_content_comment('oboGo_NADSynthaseGlutamineHydrolyzingactivity',s("Catalysis","of","the","reaction",":","ATP","+","deamido-NAD","+","+","L-glutamine","+","H2O","=","AMP","+","diphosphate","+","NAD","+","+","L-glutamate","."),4184559). assertion_content_comment('oboGo_NAlphaBenzyloxycarbonylleucinehydrolaseactivity',s("Catalysis","of","the","reaction",":","N-benzyloxycarbonyl-L-leucine","+","H","(","2",")","O","+","H","(","+",")","=","L-leucine","+","benzyl","alcohol","+","CO","(","2",")"),4370028). assertion_content_comment('oboGo_NAPESpecificphospholipasedactivity',s("Catalysis","of","the","release","of","N-acylethanolamine","from","N-acyl-phosphatidylethanolamine","(","NAPE",")","to","generate","N-acylethanolamine","(","NAE",")"),4174188). assertion_content_comment('oboGo_Naphthalene12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","naphthalene","+","NADH","+","H","+","+","O2","=","(","1R",",","2S",")","-1",",","2-dihydronaphthalene-1",",","2-diol","+","NAD","+"),4276064). assertion_content_comment('oboGo_NaphthaleneDisulfonate12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","(","1/2",")","-unsubstituted","naphthalenoid-","(","2/1",")","-sulfonate","+","2","H","+","+","2","e-","+","O2","=","1",",","2-dihydroxynaphthalene","derivative","+","HSO3","(","-",")","Substrates","include","naphthalene-1",",","6-disulfonate","(","forms","1",",","2-dihydroxynaphthalene-6-sulfonate",")",",","naphthalene-1-sulfonate","(","forms","1",",","2-dihydroxynaphthalene",")",",","naphthalene-2",",","6-disulfonate","(","forms","1",",","2-dihydroxynaphthalene-6-sulfonate",")","and","naphthalene-2-sulfonate","(","forms","1",",","2-dihydroxynaphthalene",")"),4276822). assertion_content_comment('oboGo_Naphthyl_2_Hydroxymethyl_Succinyl_CoADehydrogenaseActivity',s("Catalysis","of","the","reaction",":","naphthyl-2-hydroxymethyl-succinyl-CoA","=","naphthyl-2-oxomethyl-succinyl-CoA","+","2","H","+","+","2","e-","."),4350757). assertion_content_comment('oboGo_Naphthyl_2_Methylene_Succinyl_CoALyaseActivity',s("Catalysis","of","the","reaction",":","naphthyl-2-methylene-succinyl-CoA","+","H2O","=","naphthyl-2-hydroxymethyl-succinyl-CoA","."),4350748). assertion_content_comment('oboGo_Naphthyl_2_Methyl_SuccinateCoA_TransferaseActivity',s("Catalysis","of","the","reaction",":","naphthyl-2-methyl-succinate","+","succinyl-CoA","=","naphthyl-2-methyl-succinyl-CoA","+","succinate","."),4350730). assertion_content_comment('oboGo_Naphthyl_2_Methyl_Succinyl_CoADehydrogenaseActivity',s("Catalysis","of","the","reaction",":","naphthyl-2-methyl-succinyl-CoA","=","naphthyl-2-methylene-succinyl-CoA","+","2","H","+","+","2","e-","."),4350739). assertion_content_comment('oboGo_Naphthyl_2_Oxomethyl_Succinyl_CoASuccinylTransferaseActivity',s("Catalysis","of","the","reaction",":","naphthyl-2-oxomethyl-succinyl-CoA","+","CoASH","=","2-naphthoyl-CoA","+","succinyl-CoA","."),4350766). assertion_content_comment('oboGo_Naringenin3Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","naringenin","+","2-oxoglutarate","+","O2","=","dihydrokaempferol","+","succinate","+","CO2","."),4299780). assertion_content_comment('oboGo_NaringeninChalconesynthaseactivity',s("Catalysis","of","the","reaction",":","3","malonyl-CoA","+","4-coumaroyl-CoA","=","4","CoA","+","naringenin","chalcone","+","3","CO2","."),4303990). assertion_content_comment('oboGo_NascentPolypeptideAssociatedcomplex',s("A","heterodimeric","protein","complex","that","can","reversibly","bind","to","ribosomes",",","and","is","located","in","direct","proximity","to","newly","synthesized","polypeptide","chains","as","they","emerge","from","the","ribosome","."),4221648). assertion_content_comment('oboGo_NaturalKillerCellLectinLikereceptorbinding',s("Interacting","selectively","and","non-covalently","with","a","lectin-like","natural","killer","cell","receptor","."),4356042). assertion_content_comment('oboGo_N_Benzoyl_4_Hydroxyanthranilate4_O_MethyltransferaseActivity',s("Catalysis","of","the","reaction",":","N-benzoyl-4-hydroxyanthranilate","+","S-adenosyl-L-methionine","(","1","+",")","=","N-benzoyl-4-methoxyanthranilate","+","S-adenosyl-L-homocysteine","+","H","(","+",")"),4308529). assertion_content_comment('oboGo_NBenzyloxycarbonylglycinehydrolaseactivity',s("Catalysis","of","the","reaction",":","N-benzyloxycarbonylglycine","+","H","(","2",")","O","+","H","(","+",")","=","benzyl","alcohol","+","CO","(","2",")","+","glycine","."),4271673). assertion_content_comment('oboGo_NBoxbinding',s("Interacting","selectively","and","non-covalently","with","an","N-box",",","a","DNA","motif","with","the","consensus","sequence","CACNAG","that","is","found","in","the","promoters","of","genes","expressed","preferentially","at","synapses","."),4170912). assertion_content_comment('oboGo_NCarbamoylDAminoacidhydrolaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","N-carbamoyl-D-amino","acid","=","CO2","+","NH3","+","D-amino","acid","."),4369850). assertion_content_comment('oboGo_NCarbamoylLAminoAcidhydrolaseactivity',s("Catalysis","of","the","reaction",":","N-carbamoyl-L-2-amino","acid","+","H2O","=","L-2-amino","acid","+","NH3","+","CO2",".","The","N-carbamoyl-L-2-amino","acid","is","a","2-ureido","carboxylate","."),4268673). assertion_content_comment('oboGo_NCarbamoylputrescineamidaseactivity',s("Catalysis","of","the","reaction",":","N-carbamoylputrescine","+","H","(","2",")","O","+","2","H","(","+",")","=","CO","(","2",")","+","NH","(","4",")","(","+",")","+","putrescine","."),4271687). assertion_content_comment('oboGo_NCarbamoylsarcosineamidaseactivity',s("Catalysis","of","the","reaction",":","N-carbamoylsarcosine","+","H","(","2",")","O","+","2","H","(","+",")","=","CO","(","2",")","+","NH","(","4",")","(","+",")","+","sarcosine","."),4271746). assertion_content_comment('oboGo_NcRNA3Endprocessing',s("Any","process","involved","in","forming","the","mature","3","'","end","of","a","non-coding","RNA","molecule","."),3976097). assertion_content_comment('oboGo_NcRNA5Endprocessing',s("Any","process","involved","in","forming","the","mature","5","'","end","of","a","non-coding","RNA","molecule","."),3976179). assertion_content_comment('oboGo_NcRNAPolyadenylationInvolvedInPolyadenylationDependentncrnacatabolicprocess',s("The","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","of","a","non-coding","RNA",",","occurring","as","part","of","the","process","of","polyadenylation-dependent","non-coding","RNA","catabolism","."),4095180). assertion_content_comment('oboGo_NCyclohexylformamideamidohydrolaseactivity',s("Catalysis","of","the","reaction",":","N-cyclohexylformamide","+","OH-","=","cyclohexylamine","+","formate","."),4349645). assertion_content_comment('oboGo_NCyclopropylammelidealkylaminohydrolaseactivity',s("Catalysis","of","the","reaction",":","N-cyclopropylammelide","+","H2O","=","cyclopropylamine","+","cyanuric","acid","."),4352804). assertion_content_comment('oboGo_NCyclopropylammelinedeaminaseactivity',s("Catalysis","of","the","reaction",":","N-cyclopropylammeline","+","H2O","=","N-cyclopropylammelide","+","NH3","."),4352822). assertion_content_comment('oboGo_NCyclopropylmelaminecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","N-cyclopropylmelamine",",","a","triazine","compound","commonly","used","as","an","insecticide","."),4314497). assertion_content_comment('oboGo_NCyclopropylmelaminedeaminaseactivity',s("Catalysis","of","the","reaction",":","cyromazine","+","H2O","=","N-cyclopropylammeline","+","NH3","."),4352813). assertion_content_comment('oboGo_NCyclopropylmelaminemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","N-cyclopropylmelamine",",","a","triazine","compound","commonly","used","as","an","insect","growth","regulator","insecticide","."),4314491). assertion_content_comment('oboGo_NDPGlucoseStarchglucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","NDP-glucose","+","(","1",",","4-alpha-D-glucosyl",")","n","=","NDP","+","(","1",",","4-alpha-D-glucosyl",")","n","+","1","."),4343302). assertion_content_comment('oboGo_NEDD8ClassDependentproteincatabolicprocess',s("OBSOLETE",".","The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","a","protein","or","peptide","by","hydrolysis","of","its","peptide","bonds",",","initiated","by","covalent","attachment","of","the","ubiquitin-like","protein","NEDD8","(","RUB1",")","to","the","target","protein","."),4232929). assertion_content_comment('oboGo_NEDD8Specificproteaseactivity',s("Catalysis","of","the","hydrolysis","of","NEDD8",",","a","small","ubiquitin-related","modifier",",","from","previously","neddylated","substrates","."),4245388). assertion_content_comment('oboGo_NegativeAdaptationOfSignalingPathwayByResponseToPheromoneInvolvedInPheromoneInducedunidirectionalconjugation',s("In","organisms","that","undergo","pheromone-induced","unidirectional","conjugation",",","the","process","involved","in","desensitization","following","exposure","to","pheromone","stimulus","that","acts","to","down-regulate","further","stimulation","or","block","initial","conjugation","responses","."),4363711). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontAdenylateCyclaseMediatedsignaltransduction',s("Any","process","in","which","an","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","adenylate","cyclase-mediated","signal","transduction","in","the","symbiont","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4328204). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontCalciumOrCalmodulinMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","calcium","or","calmodulin-mediated","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153302). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontCAMPMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","cAMP-mediated","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153642). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontGProteincoupledreceptorproteinsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","symbiont","G-protein","coupled","receptor","protein","signal","transduction",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154088). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontMAPKinaseMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","symbiont","MAP","kinase-mediated","signal","transduction",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154364). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontProteinKinaseMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","protein","kinase-mediated","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154362). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontReceptorMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","receptor-mediated","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154082). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontSignalTransductionMediatedByGProteinalphasubunit',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","symbiont","signal","transduction","mediated","by","G-protein","alpha","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154091). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontSignalTransductionMediatedByGProteinbetasubunit',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","symbiont","signal","transduction","mediated","by","G-protein","beta","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154102). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontSignalTransductionMediatedByGProteingammasubunit',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","symbiont","signal","transduction","mediated","by","G-protein","gamma","subunit",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154155). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontTransmembraneReceptorMediatedcampsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","transmembrane","receptor-mediated","cAMP","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154179). assertion_content_comment('oboGo_NegativeRegulationByHostOfSymbiontTransmembraneReceptorMediatedsignaltransduction',s("Any","process","in","which","the","host","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","transmembrane","receptor-mediated","signal","transduction","in","the","symbiont",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4154085). assertion_content_comment('oboGo_NegativeRegulationByOrganismOfBCellmediatedimmuneresponseofotherorganisminvolvedinsymbioticinteraction',s("Any","process","in","which","an","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","the","B-cell","mediated","immune","response","of","a","second","organism",",","where","the","two","organisms","are","in","a","symbiotic","interaction","."),4194554). 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assertion_content_comment('oboGo_NegativeRegulationOfTHelper17celldifferentiation',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","17","cell","differentiation","."),4139639). assertion_content_comment('oboGo_NegativeRegulationOfTHelper17cellextravasation',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","17","cell","extravasation","."),4142241). assertion_content_comment('oboGo_NegativeRegulationOfTHelper17celllineagecommitment',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","17","cell","lineage","commitment","."),4143088). assertion_content_comment('oboGo_NegativeRegulationOfTHelper17typeimmuneresponse',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","17","type","immune","response","."),4139734). assertion_content_comment('oboGo_NegativeRegulationOfTHelper1cellactivation',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","1","cell","activation","."),4144843). assertion_content_comment('oboGo_NegativeRegulationOfTHelper1cellcytokineproduction',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","1","cell","cytokine","production","."),4145077). assertion_content_comment('oboGo_NegativeRegulationOfTHelper1celldifferentiation',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","1","cell","differentiation","."),4086793). assertion_content_comment('oboGo_NegativeRegulationOfTHelper1typeimmuneresponse',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","a","T-helper","1","type","immune","response","."),4000766). assertion_content_comment('oboGo_NegativeRegulationOfTHelper2cellcytokineproduction',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","2","cell","cytokine","production","."),4144980). assertion_content_comment('oboGo_NegativeRegulationOfTHelper2celldifferentiation',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","T-helper","2","cell","differentiation","."),4086858). 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assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor10signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","10","signaling","pathway","."),4075965). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor11signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","11","signaling","pathway","."),4075916). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor12signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","12","signaling","pathway","."),4076159). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor13signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","13","signaling","pathway","."),4076133). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor15signalingpathway',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","toll-like","receptor","15","signaling","pathway","."),4141958). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor1signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","1","signaling","pathway","."),4076973). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor21signalingpathway',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","toll-like","receptor","21","signaling","pathway","."),4142403). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor2signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","2","signaling","pathway","."),4076231). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor3signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","3","signaling","pathway","."),4076195). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor4signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","4","signaling","pathway","."),4076293). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor5signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","5","signaling","pathway","."),4076414). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor6signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","6","signaling","pathway","."),4076440). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor7signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","7","signaling","pathway","."),4076401). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor8signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","8","signaling","pathway","."),4076538). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptor9signalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","9","signaling","pathway","."),4076476). assertion_content_comment('oboGo_NegativeRegulationOfTollLikereceptorsignalingpathway',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","toll-like","receptor","signaling","pathway","."),4075910). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionDNADependent',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","cellular","DNA-dependent","transcription","."),3971642). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionElongationDNADependent',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","transcription","elongation",",","the","extension","of","an","RNA","molecule","after","transcription","initiation","and","promoter","clearance","by","the","addition","of","ribonucleotides","catalyzed","by","a","DNA-dependent","RNA","polymerase","."),4068999). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionFromRNAPolymeraseIIPromoterInResponseToUVInduceddnadamage',s("Any","process","that","modulates","the","frequency",",","rate","or","extent","of","transcription","from","an","RNA","polymerase","II","promoter","as","a","result","of","a","UV","damage","stimulus","."),4335831). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionInitiationDNADependent',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","DNA-dependent","transcription","initiation","."),4111692). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionMatingTypespecific',s("Any","mating-type","specific","process","that","stops",",","prevents","or","reduces","the","rate","of","transcription","."),4298238). assertion_content_comment('oboGo_NegativeRegulationOfTranscriptionTerminationDNADependent',s("Any","process","that","decreases","the","rate",",","frequency","or","extent","of","DNA-dependent","transcription","termination",",","the","process","in","which","transcription","is","completed",";","the","formation","of","phosphodiester","bonds","ceases",",","the","RNA-DNA","hybrid","dissociates",",","and","RNA","polymerase","releases","the","DNA","."),4117188). assertion_content_comment('oboGo_NegativeRegulationOfTransformingGrowthFactorBeta1production',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","production","of","transforming","growth","factor-beta1","."),4064285). assertion_content_comment('oboGo_NegativeRegulationOfTransformingGrowthFactorBeta2production',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","production","of","transforming","growth","factor-beta2","."),4064325). assertion_content_comment('oboGo_NegativeRegulationOfTransformingGrowthFactorBeta3production',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","production","of","transforming","growth","factor-beta3","."),4064365). assertion_content_comment('oboGo_NegativeRegulationOfTransformingGrowthFactorBetaproduction',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate",",","or","extent","of","production","of","transforming","growth","factor-beta","."),4064278). assertion_content_comment('oboGo_NegativeRegulationOfTranslationNcRNAMediated',s("Any","process",",","mediated","by","small","non-coding","RNAs",",","that","stops",",","prevents","or","reduces","the","rate","that","mRNAs","are","effectively","translated","into","protein","."),4070985). assertion_content_comment('oboGo_NegativeRegulationOfTransmembraneReceptorMediatedcampsignaltransductioninresponsetohost',s("Any","process","in","which","the","symbiont","organism","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","its","symbiont","transmembrane","receptor-mediated","cAMP","signal","transduction","as","a","result","of","detecting","molecules","of","its","host","organism",".","The","host","is","defined","as","the","larger","of","the","organisms","involved","in","a","symbiotic","interaction","."),4153615). 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assertion_content_comment('oboGo_NegativeRegulationOfTranspositionRNAMediated',s("Any","process","that","decreases","the","frequency",",","rate","or","extent","of","RNA-mediated","transposition",".","RNA-mediated","transposition","is","a","type","of","transpositional","recombination","which","occurs","via","an","RNA","intermediate","."),4029873). assertion_content_comment('oboGo_NegativeRegulationOfTumorNecrosisFactorMediatedsignalingpathway',s("Any","process","that","decreases","the","rate","or","extent","of","the","tumor","necrosis","factor-mediated","signaling","pathway",".","The","tumor","necrosis","factor-mediated","signaling","pathway","is","the","series","of","molecular","signals","generated","as","a","consequence","of","tumor","necrosis","factor","binding","to","a","cell","surface","receptor","."),4025911). assertion_content_comment('oboGo_NegativeRegulationOfTwoComponentsignaltransductionsystemphosphorelay',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","signal","transduction","via","a","two-component","phosphorelay","signal","transduction","system","."),4033089). assertion_content_comment('oboGo_NegativeRegulationOfTypeIIISiteSpecificdeoxyribonucleaseactivity',s("Any","process","that","stops","or","reduces","the","rate","of","Type","III","restriction","endodeoxyribonuclease","activity","."),4330963). assertion_content_comment('oboGo_NegativeRegulationOfTypeIInterferonMediatedsignalingpathway',s("Any","process","that","decreases","the","rate",",","frequency","or","extent","of","a","type","I","interferon-mediated","signaling","pathway",".","A","type","I","interferon-mediated","signaling","pathway","is","the","series","of","molecular","events","generated","as","a","consequence","of","a","type","I","interferon","binding","to","a","cell","surface","receptor","."),4114577). assertion_content_comment('oboGo_NegativeRegulationOfTypeIISiteSpecificdeoxyribonucleaseactivity',s("Any","process","that","stops","or","reduces","the","rate","of","Type","II","restriction","endodeoxyribonuclease","activity","."),4330946). assertion_content_comment('oboGo_NegativeRegulationOfTypeISiteSpecificdeoxyribonucleaseactivity',s("Any","process","that","stops","or","reduces","the","rate","of","Type","I","restriction","endodeoxyribonuclease","activity","."),4330917). assertion_content_comment('oboGo_NegativeRegulationOfTypeIVSiteSpecificdeoxyribonucleaseactivity',s("Any","process","that","stops","or","reduces","the","rate","of","Type","IV","restriction","endodeoxyribonuclease","activity","."),4330980). assertion_content_comment('oboGo_NegativeRegulationOfUbiquitinDependentendocytosis',s("Any","process","that","stops",",","prevents","or","reduces","the","frequency",",","rate","or","extent","of","ubiquitin-dependent","endocytosis","."),4142508). assertion_content_comment('oboGo_NegativeRegulationOfUbiquitinProteinligaseactivityinvolvedinmeioticcellcycle',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","ubiquitin","ligase","activity","during","the","meiotic","cell","cycle","."),4286580). assertion_content_comment('oboGo_NegativeRegulationOfUbiquitinProteinligaseactivityinvolvedinmitoticcellcycle',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","ubiquitin","ligase","activity","that","contributes","to","the","mitotic","cell","cycle","."),4117054). assertion_content_comment('oboGo_NegativeRegulationOfUbiquitinProteinligaseactivity',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","ubiquitin","ligase","activity",",","the","catalysis","of","the","reaction",":","ATP","+","ubiquitin","+","protein","lysine","=","AMP","+","diphosphate","+","protein","N-ubiquityllysine","."),4117039). assertion_content_comment('oboGo_NegativeRegulationOfUbiquitinSpecificproteaseactivity',s("Any","process","that","stops",",","prevents",",","or","reduces","the","frequency",",","rate","or","extent","of","ubiquitin-specific","protease","activity","."),4170405). assertion_content_comment('oboGo_NegativeRegulationOfUDPGlucosecatabolicprocess',s("Any","process","that","decreases","the","rate",",","frequency","or","extent","of","UDP-glucose","catabolism",".","UDP-glucose","catabolic","processes","are","the","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","UDP-glucose",",","uridinediphosphoglucose",",","a","substance","composed","of","glucose","in","glycosidic","linkage","with","uridine","diphosphate","."),4038181). assertion_content_comment('oboGo_NegativeRegulationOfVacuoleFusionNonAutophagic',s("Any","process","that","decreases","the","frequency",",","rate","or","extent","of","the","fusion","of","two","vacuole","membranes","to","form","a","single","vacuole","."),4136129). assertion_content_comment('oboGo_NegativeRegulationOfVeryLowDensitylipoproteinparticleclearance',s("Any","process","that","decreases","the","rate",",","frequency","or","extent","of","very-low-density","lipoprotein","particle","clearance",".","Very-low-density","lipoprotein","particle","clearance","is","the","process","in","which","a","very-low-density","lipoprotein","particle","is","removed","from","the","blood","via","receptor-mediated","endocytosis","and","its","constituent","parts","degraded","."),4038403). 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assertion_content_comment('oboGo_NeolactotetraosylceramideAlpha_23_SialyltransferaseActivity',s("Catalysis","of","the","reaction",":","CMP-N-acetylneuraminate","+","beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-beta-D-glucosylceramide","=","CMP","+","alpha-N-acetylneuraminyl-2",",","3-beta-D-galactosyl-1",",","4-N-acetyl-beta-D-glucosaminyl-1",",","3-beta-D-galactosyl-1",",","4-D-glucosylceramide","."),4205210). assertion_content_comment('oboGo_Neomentholdehydrogenaseactivity',s("Catalysis","of","the","reaction",":","(","+",")","-neomenthol","+","NADP","(","+",")","=","(","2S",",","5R",")","-menthone","+","H","(","+",")","+","NADPH","."),4371729). assertion_content_comment('oboGo_NEthylammelinechlorohydrolaseactivity',s("Catalysis","of","the","reaction",":","deethylsimazine","+","H2O","=","N-ethylammeline","+","chloride","+","H","+"),4303940). assertion_content_comment('oboGo_NEthylmaleimidereductaseactivity',s("Catalysis","of","the","reaction",":","N-ethylmaleimide","+","2","H","+","=","N-ethylsuccinimide","."),4251349). assertion_content_comment('oboGo_NeuErbB_2ReceptorActivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4214034). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacfibroblastcelldevelopment',s("The","process","whose","specific","outcome","is","the","progression","of","a","cardiac","fibroblast","over","time",",","from","its","formation","from","a","neural","crest","cell","to","the","mature","state",".","A","cardiac","fibroblast","is","a","connective","tissue","cell","of","the","heart","which","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4112895). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacfibroblastcelldifferentiation',s("The","process","in","which","a","neural","crest","cell","acquires","the","specialized","structural","and/or","functional","features","of","a","cardiac","fibroblast",".","A","cardiac","fibroblast","is","a","connective","tissue","cell","in","the","heart","which","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4112875). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacfibroblastcellfatecommitment',s("The","commitment","of","neural","crest","cells","to","a","cardiac","fibroblast","fate","and","their","capacity","to","differentiate","into","cardiac","fibroblast","cells",".","A","cardiac","fibroblast","is","a","connective","tissue","cell","in","the","heart","which","secretes","an","extracellular","matrix","rich","in","collagen","and","other","macromolecules","."),4112915). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacglialcelldevelopment',s("The","process","aimed","at","the","progression","of","a","neural","crest-derived","cardiac","glial","cell","over","time",",","from","initial","commitment","of","the","cell","to","a","specific","fate",",","to","the","fully","functional","differentiated","cell","."),4112792). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacglialcelldifferentiation',s("The","process","in","which","a","neural","crest","cell","acquires","the","specialized","features","of","a","glial","cell","of","the","heart","."),4112782). assertion_content_comment('oboGo_NeuralCrestDerivedcardiacglialcellfatecommitment',s("The","commitment","of","neural","crest","cells","to","cardiac","glial","cell","fates","and","their","capacity","to","differentiate","into","cardiac","glial","cells","."),4112802). assertion_content_comment('oboGo_NeuroblastDivision_9',s("OBSOLETE",".","The","asymmetrical","division","of","a","neuroblast",",","the","neural","precursor","in","the","central","nervous","system",",","giving","rise","to","another","neuroblast","and","a","ganglion","mother","cell","."),4300846). assertion_content_comment('oboGo_NeuronalCdc2Likekinasebinding',s("Interacting","selectively","and","non-covalently","with","neuronal","Cdc2-like","kinase",",","an","enzyme","involved","in","the","regulation","of","neuronal","differentiation","and","neuro-cytoskeleton","dynamics","."),4314716). assertion_content_comment('oboGo_NeuronalGlialinteractioninvolvedincerebralcortexradialgliaguidedmigration',s("The","changes","in","adhesion","between","neuronal","cells","and","glial","cells","as","a","component","of","the","process","of","cerebral","cortex","glial-mediated","radial","cell","migration","."),4049914). assertion_content_comment('oboGo_NeuronalGlialinteractioninvolvedinhindbrainglialMediatedradialcellmigration',s("The","changes","in","adhesion","between","a","neuronal","cell","and","a","glial","cell","as","a","component","of","the","process","of","hindbrain","glial-mediated","radial","cell","migration","."),4047920). assertion_content_comment('oboGo_NeuronCellCelladhesion',s("The","attachment","of","a","neuron","to","another","cell","via","adhesion","molecules","."),4236187). assertion_content_comment('oboGo_NeuronNeuronsynaptictransmission',s("The","process","of","communication","from","a","neuron","to","another","neuron","across","a","synapse","."),4054281). assertion_content_comment('oboGo_NeuronProducingasymmetricradialglialcelldivisioninforebrain',s("The","unequal","mitotic","division","of","a","radial","glial","cell","in","the","forebrain","that","gives","rise","to","a","radial","glial","cell","and","a","post-mitotic","neuronal","progenitor","."),4047295). assertion_content_comment('oboGo_NeurotensinReceptorActivityGProteincoupled',s("Combining","with","the","tridecapeptide","neurotensin","to","initiate","a","G-protein","mediated","change","in","cell","activity",".","A","G-protein","is","a","signal","transduction","molecule","that","alternates","between","an","inactive","GDP-bound","and","an","active","GTP-bound","state","."),4304980). assertion_content_comment('oboGo_NeurotensinReceptorActivityNonGProteincoupled',s("Combining","with","neurotensin",",","a","neuropeptide","active","in","the","central","and","peripheral","nervous","system","in","mammals",",","to","initiate","a","change","in","cell","activity","by","a","mechanism","independent","of","coupling","to","G","proteins","."),4309393). assertion_content_comment('oboGo_NeurotransmitterGatedionchannelclustering',s("The","receptor","clustering","process","in","which","neurotransmitter-gated","ion","channels","are","localized","to","distinct","domains","in","the","cell","membrane","."),4125979). assertion_content_comment('oboGo_NeurotransmitterMediatedguidanceofinterneuronsinvolvedinsubstrateIndependentcerebralcortextangentialmigration',s("The","response","of","migrating","interneurons","to","neurotransmitters","that","alter","electrical","activity","in","cells","in","calcium","dependent","manner","."),4050917). assertion_content_comment('oboGo_Neurotrophin_3Binding',s("Interacting","selectively","and","non-covalently","with","neurotrophin-3","."),4214065). assertion_content_comment('oboGo_Neurotrophin_45Binding',s("Interacting","selectively","and","non-covalently","with","neurotrophin-4/5","."),4214146). assertion_content_comment('oboGo_NeutralLAminoacidsecondaryactivetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","neutral","L-amino","acid","from","one","side","of","a","membrane","to","the","other",",","up","its","concentration","gradient",".","The","transporter","binds","the","solute","and","undergoes","a","series","of","conformational","changes",".","Transport","works","equally","well","in","either","direction","and","is","driven","by","a","chemiosmotic","source","of","energy",".","Chemiosmotic","sources","of","energy","include","uniport",",","symport","or","antiport","."),4215829). assertion_content_comment('oboGo_NeutrophilMediatedKillingOfGramNegativebacterium',s("The","directed","killing","of","a","gram-negative","bacterium","by","a","neutrophil","."),4131693). assertion_content_comment('oboGo_NeutrophilMediatedKillingOfGramPositivebacterium',s("The","directed","killing","of","a","gram-positive","bacterium","by","a","neutrophil","."),4131729). assertion_content_comment('oboGo_NFeruloylglycinedeacylaseactivity',s("Catalysis","of","the","reaction",":","N-feruloylglycine","+","H","(","2",")","O","=","ferulate","+","glycine","."),4271758). assertion_content_comment('oboGo_NFKappabbinding',s("Interacting","selectively","and","non-covalently","with","NF-kappaB",",","a","transcription","factor","for","eukaryotic","RNA","polymerase","II","promoters","."),4287000). assertion_content_comment('oboGo_NFKappabcomplex',s("A","protein","complex","that","consists","of","a","homo-","or","heterodimer","of","members","of","a","family","of","structurally","related","proteins","that","contain","a","conserved","N-terminal","region","called","the","Rel","homology","domain","(","RHD",")","In","the","nucleus",",","NF-kappaB","complexes","act","as","transcription","factors",".","In","unstimulated","cells",",","NF-kappaB","dimers","are","sequestered","in","the","cytoplasm","by","IkappaB","monomers",";","signals","that","induce","NF-kappaB","activity","cause","degradation","of","IkappaB",",","allowing","NF-kappaB","dimers","to","translocate","to","the","nucleus","and","induce","gene","expression","."),4164730). assertion_content_comment('oboGo_NFKappabimportintonucleus',s("The","directed","movement","of","NF-kappaB",",","a","transcription","factor","for","eukaryotic","RNA","polymerase","II","promoters",",","from","the","cytoplasm","into","the","nucleus",",","across","the","nuclear","membrane","."),4016308). assertion_content_comment('oboGo_NFKappabInducingkinaseactivity',s("Catalysis","of","the","phosphorylation","of","the","alpha","or","beta","subunit","of","the","inhibitor","of","kappaB","kinase","complex","(","IKK",")"),4200677). assertion_content_comment('oboGo_NFKappabp50p65complex',s("A","heterodimer","of","NF-kappa","B","p50","and","p65","subunits","."),4379114). assertion_content_comment('oboGo_NFormylglutamatedeformylaseactivity',s("Catalysis","of","the","reaction",":","N-formyl-L-glutamate","+","H","(","2",")","O","=","L-glutamate","+","formate","."),4271728). assertion_content_comment('oboGo_NFormylmethionylaminoacylTrnadeformylaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","charged-fMet-tRNAs","=","L-methionylaminoacyl-tRNA","+","formate","."),4370066). assertion_content_comment('oboGo_NFormylpeptidereceptoractivity',s("Combining","with","an","N-formyl","peptide","to","initiate","a","change","in","cell","activity","."),4198894). assertion_content_comment('oboGo_NGFTNF6CDomainreceptoractivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4213989). assertion_content_comment('oboGo_NGlycandiversification',s("The","generation",",","in","the","Golgi","apparatus",",","of","side","chain","diversity","from","high","mannose","Man5GlcNAc2-Asn","N-glycans","by","specific","glycosyltransferases","and","glycosidases","."),4303740). assertion_content_comment('oboGo_NGlycanprocessing',s("The","conversion","of","N-linked","glycan","(","N","=","nitrogen",")","structures","from","the","initially","transferred","oligosaccharide","to","a","mature","form",",","by","the","actions","of","glycosidases","and","glycosyltransferases",".","The","early","processing","steps","are","conserved","and","play","roles","in","glycoprotein","folding","and","trafficking","."),4009853). assertion_content_comment('oboGo_NGlycanprocessingtolysosome',s("The","modification","of","high-mannose","N-glycans","by","UDP-N-acetylglucosamine-lysosomal-enzyme","N-acetylglucosaminephosphotransferase","and","the","subsequent","removal","of","the","N-acetylglucosamine","residues","yielding","mannose-6-P","that","occurs","in","the","ER-Golgi","apparatus","to","N-glycans","destined","for","the","lysosome","."),4034748). assertion_content_comment('oboGo_NGlycanprocessingtosecretedandcellSurfacenGlycans',s("The","modification","of","high-mannose","(","Man9-Asn",")","N-glycans","by","mannosyl-oligosaccharide","1",",","2-alpha-mannosidase",".","This","may","result","in","Man8GlcNAc2-Asn","N-glycans","(","which","in","yeast","may","be","subsequently","modified","by","the","addition","of","further","mannose","residues",")","or","Man5GlcNAc2-Asn","N-glycans","that","are","substrates","for","further","diversification","in","the","Golgi","apparatus","."),4303750). assertion_content_comment('oboGo_N_Hydroxy_2_AcetamidofluoreneReductaseActivity',s("Catalysis","of","the","reaction",":","2-acetamidofluorene","+","NAD","(","P",")","+","+","H2O","=","N-hydroxy-2-acetamidofluorene","+","NAD","(","P",")","H","+","H","+"),4365578). assertion_content_comment('oboGo_NHydroxyarylamineoAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","acetyl-CoA","+","an","N-hydroxyarylamine","=","CoA","+","an","N-acetoxyarylamine","."),4361716). assertion_content_comment('oboGo_NickelIncorporationIntoIronSulfurclusterviatrisLCysteinyllCysteinepersulfidobisLGlutamatolHistidinonickeltriirondisulfidetrioxide',s("The","incorporation","of","nickel","into","a","3Fe-2S","complex","by","tris-L-cysteinyl","L-cysteine","persulfido","bis-L-glutamato","L-histidino","nickel","triiron","disulfide","trioxide","."),4281526). assertion_content_comment('oboGo_NickelIncorporationIntoIronSulfurclusterviatrisLCysteinyllCysteinepersulfidolGlutamatolHistidinolSerinylnickeltriirondisulfidetrioxide',s("The","incorporation","of","nickel","into","a","3Fe-2S","complex","by","tris-L-cysteinyl","L-cysteine","persulfido","L-glutamato","L-histidino","L-serinyl","nickel","triiron","disulfide","trioxide","."),4281497). assertion_content_comment('oboGo_NickelIncorporationIntoMetalloSulfurcluster',s("The","incorporation","of","nickel","into","a","metallo-sulfur","cluster","."),4281494). assertion_content_comment('oboGo_NickelIncorporationIntoNickelIronSulfurclusterviapentakisLCysteinyllHistidinonickeltetraironpentasulfide',s("The","incorporation","of","nickel","into","a","nickel-iron-sulfur","cluster","via","pentakis-L-cysteinyl","L-histidino","nickel","tetrairon","pentasulfide",",","found","in","carbon","monoxide","dehydrogenase","."),4306481). assertion_content_comment('oboGo_NickelTetrapyrrolecoenzymemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","an","enzyme","cofactor","consisting","of","a","tetrapyrrole","structure","containing","nickel",",","such","as","the","F-430","cofactor","found","in","methyl-coenzyme","M","reductase","."),4040499). assertion_content_comment('oboGo_NickelTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","Ni2","+","(","out",")","=","ADP","+","phosphate","+","Ni2","+","(","in",")"),4291501). assertion_content_comment('oboGo_NicotinamideNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","nicotinamide","=","1-methylnicotinamide","+","S-adenosyl-L-homocysteine","."),4246253). assertion_content_comment('oboGo_NicotinamideNucleotideadenylyltransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","nicotinamide","nucleotide","=","diphosphate","+","NAD","+"),4363001). assertion_content_comment('oboGo_NicotinamideNucleotideamidaseactivity',s("Catalysis","of","the","reaction",":","beta-nicotinamide","D-ribonucleotide","+","H2O","=","beta-nicotinate","D-ribonucleotide","+","NH3","."),4237584). assertion_content_comment('oboGo_NicotinateNMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","S-adenosyl-L-methionine","(","1","+",")","+","nicotinate","=","N-methylnicotinate","+","S-adenosyl-L-homocysteine","."),4248786). assertion_content_comment('oboGo_NicotinateNucleotideadenylyltransferaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","nicotinate","ribonucleotide","=","diphosphate","+","deamido-NAD","+"),4205174). assertion_content_comment('oboGo_NicotinateNucleotideDimethylbenzimidazolephosphoribosyltransferaseactivity',s("Catalysis","of","the","reaction",":","5",",","6-dimethylbenzimidazole","+","nicotinate","D-ribonucleotide","=","alpha-ribazole","5","'","-phosphate","+","H","(","+",")","+","nicotinate","."),4247451). assertion_content_comment('oboGo_NicotinateNucleotidediphosphorylasecarboxylatingactivity',s("Catalysis","of","the","reaction",":","CO","(","2",")","+","diphosphate","+","nicotinate","D-ribonucleotide","=","5-phospho-alpha-D-ribose","1-diphosphate","+","2","H","(","+",")","+","quinolinate","."),4205193). assertion_content_comment('oboGo_NicotinicAcetylcholineActivatedcationSelectivechannelactivity',s("Catalysis","of","the","transmembrane","transfer","of","a","cation","by","a","channel","that","acts","as","a","nicotinic","acetylcholine","receptor",",","and","opens","upon","binding","acetylcholine","."),4200033). assertion_content_comment('oboGo_NicotinicAcetylcholineGatedreceptorChannelcomplex',s("A","protein","complex","that","acts","as","an","acetylcholine","receptor",",","and","forms","a","transmembrane","channel","through","which","ions","may","pass","in","response","to","ligand","binding",".","The","complex","is","a","homo-","or","heteropentamer","of","subunits","that","are","members","of","a","neurotransmitter","receptor","superfamily","."),4008352). assertion_content_comment('oboGo_NicotinicAcetylcholineReceptorAssociatedproteinactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4257866). assertion_content_comment('oboGo_NIsopropylacetanilideamidohydrolaseactivity',s("Catalysis","of","the","reaction",":","N-isopropylacetanilide","+","OH-","=","N-isopropylaniline","+","acetate","."),4352696). assertion_content_comment('oboGo_NIsopropylacetanilinemonooxygenaseactivity',s("Catalysis","of","the","reaction",":","N-isopropylacetanilide","+","1/2","O2","=","acetanilide","+","acetone","."),4352687). assertion_content_comment('oboGo_NIsopropylammelideisopropylaminohydrolaseactivity',s("Catalysis","of","the","reaction",":","N-isopropylammelide","+","H2O","=","cyanuric","acid","+","isopropylamine","."),4274574). assertion_content_comment('oboGo_NIsopropylaniline12Dixoxygenaseactivity',s("Catalysis","of","the","reaction",":","N-isopropylaniline","+","O2","+","2","H","+","+","NADH","=","catechol","+","NAD","+","+","isopropylamine","."),4350178). assertion_content_comment('oboGo_NitrateReductaseNADPHActivity_4',s("Catalysis","of","the","reaction",":","nitrite","+","NADP","+","+","H2O","=","nitrate","+","NADPH","+","H","+"),4266271). assertion_content_comment('oboGo_NitrateTransmembraneTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","nitrate","(","out",")","=","ADP","+","phosphate","+","nitrate","(","in",")"),4291385). assertion_content_comment('oboGo_NitricOxidesynthase2biosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","nitric-oxide","synthase","2",",","an","enzyme","which","catalyzes","the","reaction","L-arginine","+","n","NADPH","+","n","H","+","+","m","O2","=","citrulline","+","nitric","oxide","+","n","NADP","+"),4122003). assertion_content_comment('oboGo_NitricOxidesynthaseactivity',s("Catalysis","of","the","reaction",":","L-arginine","+","n","NADPH","+","n","H","+","+","m","O2","=","citrulline","+","nitric","oxide","+","n","NADP","+"),4205075). assertion_content_comment('oboGo_NitricOxidesynthasebinding',s("Interacting","selectively","and","non-covalently","with","the","enzyme","nitric-oxide","synthase","."),4273053). assertion_content_comment('oboGo_NitricOxidesynthasebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","nitric-oxide","synthase",",","an","enzyme","which","catalyzes","the","reaction","L-arginine","+","n","NADPH","+","n","H","+","+","m","O2","=","citrulline","+","nitric","oxide","+","n","NADP","+"),4122077). assertion_content_comment('oboGo_NitricOxidesynthaseregulatoractivity',s("Modulates","the","activity","of","nitric","oxide","synthase","."),4311675). assertion_content_comment('oboGo_NitriteReductaseCytochromeAmmoniaFormingactivity',s("Catalysis","of","the","reaction",":","NH3","+","2","H2O","+","6","ferricytochrome","c","=","nitrite","+","6","ferrocytochrome","c","+","7","H","+"),4314545). assertion_content_comment('oboGo_NitriteReductaseNOFormingactivity',s("Catalysis","of","the","reaction",":","nitric","oxide","+","H2O","+","ferricytochrome","c","=","nitrite","+","ferrocytochrome","c","+","2","H","+"),4266893). assertion_content_comment('oboGo_Nitrobenzene12Dioxygenaseactivity',s("Catalysis","of","the","reaction",":","nitrobenzene","+","NADH","+","O2","=","NAD","+","+","nitrite","+","catechol","."),4276973). assertion_content_comment('oboGo_NitroquinolineNOxidereductaseactivity',s("Catalysis","of","the","reaction",":","4-","(","hydroxyamino",")","quinoline","N-oxide","+","2","NAD","(","P",")","+","+","H2O","=","4-nitroquinoline","N-oxide","+","2","NAD","(","P",")","H","+","2","H","+"),4266256). assertion_content_comment('oboGo_NitrousOxidereductaseactivity',s("Catalysis","of","the","reaction",":","nitrogen","+","H2O","+","acceptor","=","nitrous","oxide","+","reduced","acceptor","."),4265708). assertion_content_comment('oboGo_NLongChainAcylethanolaminedeacylaseactivity',s("Catalysis","of","the","reaction",":","H2O","+","N-","(","long-chain-acyl",")","ethanolamine","=","ethanolamine","+","a","fatty","acid","."),4370076). assertion_content_comment('oboGo_NLSBearingsubstrateimportintonucleus',s("The","directed","movement","of","a","protein","bearing","a","nuclear","localization","signal","(","NLS",")","from","the","cytoplasm","into","the","nucleus",",","across","the","nuclear","membrane","."),4230266). assertion_content_comment('oboGo_NLSDependentproteinnuclearimportcomplex',s("A","protein","complex","which","usually","consists","of","three","components",",","e.g",".","in","Xenopus",",","the","importin","alpha","and","beta-subunits","and","any","protein","which","has","a","nuclear","localization","sequence","(","NLS",")","The","complex","acts","to","import","proteins","with","an","NLS","into","the","nucleus","through","a","nuclear","pore","."),4316638). assertion_content_comment('oboGo_NMalonyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","malonyl","group","to","a","nitrogen","atom","on","the","acceptor","molecule","."),4275801). assertion_content_comment('oboGo_NMalonylureahydrolaseactivity',s("Catalysis","of","the","reaction",":","3-oxo-3-ureidopropanoate","+","H","(","2",")","O","=","H","(","+",")","+","malonate","+","urea","."),4345079). assertion_content_comment('oboGo_N_Methyl_2_OxoglutaramateHydrolaseActivity',s("Catalysis","of","the","reaction",":","N-methyl-2-oxoglutaramate","+","H","(","2",")","O","=","2-oxoglutarate","+","methylammonium","."),4271662). assertion_content_comment('oboGo_NMethylalaninedehydrogenaseactivity',s("Catalysis","of","the","reaction",":","N-methyl-L-alanine","+","H","(","2",")","O","+","NADP","(","+",")","=","H","(","+",")","+","methylammonium","+","NADPH","+","pyruvate","."),4271641). assertion_content_comment('oboGo_NMethylcoclaurine3Monooxygenaseactivity',s("Catalysis","of","the","reaction",":","(","S",")","-N-methylcoclaurine","+","H","(","+",")","+","NADPH","+","O","(","2",")","=","(","S",")","-3","'","-hydroxy-N-methylcoclaurine","+","H","(","2",")","O","+","NADP","(","+",")"),4267994). assertion_content_comment('oboGo_NMethylDAspartatereceptorAssociatedproteinactivity',s("OBSOLETE","(","was","not","defined","before","being","made","obsolete",")"),4198004). assertion_content_comment('oboGo_NMethylDAspartateselectiveglutamatereceptoractivity',s("An","ionotropic","glutamate","receptor","activity","that","exhibits","slow","gating","by","glutamate",",","acts","by","opening","a","nonselective","cation","channel",",","and","can","be","activated","by","L-aspartate","."),4198035). assertion_content_comment('oboGo_NMethylDAspartateselectiveglutamatereceptorcomplex',s("An","assembly","of","four","or","five","subunits","which","form","a","structure","with","an","extracellular","N-terminus","and","a","large","loop","that","together","form","the","ligand","binding","domain",".","The","C-terminus","is","intracellular",".","The","ionotropic","glutamate","receptor","complex","itself","acts","as","a","ligand","gated","ion","channel",";","on","binding","glutamate",",","charged","ions","pass","through","a","channel","in","the","center","of","the","receptor","complex",".","NMDA","receptors","are","composed","of","assemblies","of","NR1","subunits","(","Figure","3",")","and","NR2","subunits",",","which","can","be","one","of","four","separate","gene","products","(","NR2A-D",")","Expression","of","both","subunits","are","required","to","form","functional","channels",".","The","glutamate","binding","domain","is","formed","at","the","junction","of","NR1","and","NR2","subunits",".","NMDA","receptors","are","permeable","to","calcium","ions","as","well","as","being","permeable","to","other","ions",".","Thus","NMDA","receptor","activation","leads","to","a","calcium","influx","into","the","post-synaptic","cells",",","a","signal","thought","to","be","crucial","for","the","induction","of","NMDA-receptor","dependent","LTP","and","LTD","."),4258068). assertion_content_comment('oboGo_NMethylhydantoinaseatpHydrolyzingactivity',s("Catalysis","of","the","reaction",":","N-methylhydantoin","+","ATP","+","2","H","(","2",")","O","=","N-carbamoylsarcosine","+","ADP","+","3","H","(","+",")","+","phosphate","."),4369918). assertion_content_comment('oboGo_NMethylLAminoAcidoxidaseactivity',s("Catalysis","of","the","reaction",":","an","N-methyl-L-amino","acid","+","H2O","+","O2","=","an","L-amino","acid","+","formaldehyde","+","H2O2","."),4271651). assertion_content_comment('oboGo_NMethylnucleosidaseactivity',s("Catalysis","of","the","reaction",":","7-methylxanthosine","+","H","(","2",")","O","=","7-methylxanthine","+","H","(","+",")","+","ribofuranose","."),4344578). assertion_content_comment('oboGo_NMethylphosphoethanolaminecytidylyltransferaseactivity',s("Catalysis","of","the","reaction",":","N-methylethanolamine","phosphate","+","CTP","=","CDP-N-methylethanolamine","+","diphosphate","."),4367950). assertion_content_comment('oboGo_NMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","to","the","nitrogen","atom","of","an","acceptor","molecule","."),4164119). assertion_content_comment('oboGo_NNDimethylformamidaseactivity',s("Catalysis","of","the","reaction",":","N",",","N-dimethylformamide","+","H","(","2",")","O","=","dimethylamine","+","formate","."),4271861). assertion_content_comment('oboGo_NNitrodimethylaminehydroxylaseactivity',s("Catalysis","of","the","reaction",":","N-nitrodimethylamine","+","O2","+","2","H","+","+","2","e-","=","N-nitromethylamine","+","formaldehyde","+","H2O","."),4351178). assertion_content_comment('oboGo_Noc1pNoc2pcomplex',s("A","heterodimer","associated","with","90S","and","66S","preribosomes","in","the","nucleolus",";","involved","in","ribosomal","large","subunit","biogenesis","."),4051924). assertion_content_comment('oboGo_Noc2pNoc3pcomplex',s("A","heterodimer","associated","with","66S","preribosomes",";","also","found","throughout","the","nucleoplasm",";","involved","in","ribosomal","large","subunit","biogenesis","."),4051938). assertion_content_comment('oboGo_Noc4pNop14pcomplex',s("A","heterodimer","associated","with","precursors","of","the","eukaryotic","small","ribosomal","subunit",",","including","the","90S","preribosome",";","involved","in","small","subunit","biogenesis","."),4051963). assertion_content_comment('oboGo_NocardicinAepimeraseactivity',s("Catalysis","of","the","reaction",":","isonocardicin","A","=","nocardicin","A","."),4271505). assertion_content_comment('oboGo_NociceptinOrphaninFqreceptoractivity',s("Combining","with","the","peptide","nociceptin/orphanin-FQ","to","initiate","a","change","in","cell","activity","."),4383875). assertion_content_comment('oboGo_NOctanemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","n-octane",",","the","8","carbon","straight","chain","alkane","used","in","organic","syntheses",",","calibrations",",","and","azeotropic","distillations",".","It","is","a","common","component","of","gasoline","and","other","petroleum","products","and","the","engine","fuel","antiknocking","properties","of","an","isomer","of","n-octane","are","used","as","a","comparative","standard","in","the","Octane","Rating","System","."),4241009). assertion_content_comment('oboGo_NOctaneoxidation',s("The","chemical","reactions","and","pathways","resulting","in","the","conversion","of","n-octane","to","octanoyl-CoA","."),4241013). assertion_content_comment('oboGo_NonCanonicalwntreceptorsignalingpathwayinvolvedinheartdevelopment',s("The","series","of","molecular","signals","initiated","by","binding","of","a","Wnt","protein","to","a","frizzled","family","receptor","on","the","surface","of","the","target","cell",",","followed","by","propagation","of","the","signal","via","effectors","other","than","beta-catenin","and","contributing","to","the","progression","of","the","heart","over","time","."),4135040). assertion_content_comment('oboGo_NonCanonicalwntreceptorsignalingpathway',s("The","series","of","molecular","signals","initiated","by","binding","of","a","Wnt","protein","to","a","frizzled","family","receptor","on","the","surface","of","the","target","cell",",","followed","by","propagation","of","the","signal","via","effectors","other","than","beta-catenin","."),4004455). assertion_content_comment('oboGo_NonChaperoninmolecularchaperoneatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","This","is","a","highly","diverse","group","of","enzymes","that","perform","many","functions","that","are","similar","to","those","of","chaperonins",".","They","comprise","a","number","of","heat-shock-cognate","proteins",".","They","are","also","active","in","clathrin","uncoating","and","in","the","oligomerization","of","actin","."),4252593). assertion_content_comment('oboGo_NonClassicalarabinogalactanproteinmetabolicprocess',s("The","chemical","reactions","and","pathways","involving","a","cell","wall","arabinogalactan","II","glycoprotein","where","other","amino","acids","besides","Hyp",",","Ala",",","Ser",",","Thr","and","Gly","can","be","present","and","grouped","into","regions",",","such","as","a","Cys-rich","or","Asn-rich","domains","."),4333011). assertion_content_comment('oboGo_NonCovalentchromatinmodification',s("The","alteration","of","DNA","or","protein","in","chromatin","by","the","non-covalent","addition","or","removal","of","chemical","groups","."),4305565). assertion_content_comment('oboGo_NonGlycolyticfermentation',s("Fermentation","that","does","not","include","the","anaerobic","conversion","of","glucose","to","pyruvate","via","the","glycolytic","pathway","."),4243180). assertion_content_comment('oboGo_NonInteinMediatedproteinsplicing',s("The","post-translational","removal","of","peptide","sequences","from","within","a","protein","sequence",",","by","a","process","not","involving","inteins","."),4307685). assertion_content_comment('oboGo_NonKinasephorbolesterreceptoractivity',s("Phorbol","ester/diacylglycerol","binding","proteins","that","do","not","have","intrinsic","kinase","activity","."),4361347). assertion_content_comment('oboGo_NonLyticviralexocytosis',s("The","exit","of","the","virion","particle","from","the","host","cell","by","exocytosis",",","without","causing","cell","lysis","."),4356852). assertion_content_comment('oboGo_NonLyticviralrelease',s("The","release","of","virion","particles","from","the","cell","that","does","not","result","in","cell","lysis","."),4355055). assertion_content_comment('oboGo_NonLyticvirusbuddingfromermembrane',s("A","form","of","viral","release","in","which","the","nucleocapsid","evaginates","from","the","host","endoplasmic","reticulum","membrane","system",",","resulting","in","envelopment","of","the","virus","without","triggering","cell","lysis","."),4355061). assertion_content_comment('oboGo_NonLyticvirusbuddingfromgolgimembrane',s("A","form","of","viral","release","in","which","the","nucleocapsid","evaginates","from","the","host","Golgi","membrane","system",",","resulting","in","envelopment","of","the","virus","without","triggering","cell","lysis","."),4355106). assertion_content_comment('oboGo_NonLyticvirusbuddingfromplasmamembrane',s("A","form","of","viral","release","in","which","the","nucleocapsid","evaginates","from","the","host","plasma","membrane","system",",","resulting","in","envelopment","of","the","virus","without","triggering","cell","lysis","."),4355084). assertion_content_comment('oboGo_NonLyticvirusbudding',s("A","form","of","viral","release","in","which","the","viral","particles","bud","out","through","cellular","membranes","without","causing","cell","lysis",".","It","is","also","a","form","of","viral","envelopment","."),4355057). assertion_content_comment('oboGo_NonMembraneBoundedorganelle',s("Organized","structure","of","distinctive","morphology","and","function",",","not","bounded","by","a","lipid","bilayer","membrane",".","Includes","ribosomes",",","the","cytoskeleton","and","chromosomes","."),3971803). assertion_content_comment('oboGo_NonMembranespanningproteintyrosinekinaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","a","non-membrane","spanning","protein","L-tyrosine","=","ADP","+","a","non-membrane","spanning","protein","L-tyrosine","phosphate","."),4201031). assertion_content_comment('oboGo_NonMembranespanningproteintyrosinephosphataseactivity',s("Catalysis","of","the","reaction",":","non-membrane","spanning","protein","tyrosine","phosphate","+","H2O","=","non-membrane","spanning","protein","tyrosine","+","phosphate","."),4200929). assertion_content_comment('oboGo_NonmuscleAlphaActininbinding',s("Interacting","selectively","and","non-covalently","with","nonmuscle","isoforms","of","actinin",".","Nonmuscle","alpha-actinin","is","found","at","the","leading","edge","of","motile","cells",",","cell","adhesion","sites",",","focal","contacts","and","along","actin","stress","fibers","in","migrating","cells","."),4286087). assertion_content_comment('oboGo_NonMyelinatedaxonensheathmentincentralnervoussystem',s("The","process","in","which","a","non-myelinating","glial","cell","membrane","encircles","an","axon","in","the","central","nervous","system","."),4329891). assertion_content_comment('oboGo_NonMyelinatedaxonensheathment',s("The","process","in","which","a","non-myelinating","glial","cell","membrane","closes","around","an","axon","."),4329869). assertion_content_comment('oboGo_NonPhosphorylatedglucosecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","non-phosphorylated","forms","of","glucose","."),4243397). assertion_content_comment('oboGo_NonPhosphorylatedglucosemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","non-phosphorylated","forms","of","glucose","."),4243394). assertion_content_comment('oboGo_NonPhotoreactivednarepair',s("A","DNA","repair","process","that","is","involved","in","repairing","UV-induced","DNA","damage","under","non-photoreactivating","conditions",".","The","mechanism","by","which","this","repair","process","operates","has","not","yet","been","completely","elucidated","."),4335689). assertion_content_comment('oboGo_NonpolarAminoacidTransportingatpaseactivity',s("Catalysis","of","the","transfer","of","a","solute","or","solutes","from","one","side","of","a","membrane","to","the","other","according","to","the","reaction",":","ATP","+","H2O","+","nonpolar","amino","acid","(","out",")","=","ADP","+","phosphate","+","nonpolar","amino","acid","(","in",")"),4289759). assertion_content_comment('oboGo_NonProfessionalantigenpresentingcellantigenprocessingandpresentation',s("The","process","in","which","a","non-professional","antigen","presenting","cell","expresses","antigen","(","peptide","or","lipid",")","on","its","cell","surface","in","association","with","an","MHC","protein","complex",".","Non-professional","antigen","presenting","cells","include","all","cell","types","but","dendritic","cells",",","B","cells",",","T","cells",",","monocytes",",","macrophages",",","and","neutrophils","."),3994481). assertion_content_comment('oboGo_NonRecombinationalrepair',s("A","DNA","repair","process","in","which","that","does","not","require","the","exchange","of","genetic","material","between","the","broken","DNA","molecule","and","a","homologous","region","of","DNA","."),3977976). assertion_content_comment('oboGo_NonSegmentedviralgenome',s("A","viral","genome","that","consists","of","one","continuous","nucleic","acid","molecule","."),4236375). assertion_content_comment('oboGo_NonSensoryhairorganization',s("A","process","that","is","carried","out","at","the","cellular","level","which","results","in","the","assembly",",","arrangement","of","constituent","parts",",","or","disassembly","of","non-sensory","hairs",".","These","hairs","are","polarized","cellular","extensions","that","cover","much","of","the","insect","epidermis","."),3982393). assertion_content_comment('oboGo_NonTyrosinekinasefibroblastgrowthfactorreceptoractivity',s("A","receptor","belonging","to","the","FGFR","family","but","lacking","the","tyrosine","kinase","domain","."),4361459). assertion_content_comment('oboGo_NorepinephrineEpinephrinecatabolicprocessinbloodstream',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","norepinephrine","or","epinephrine","in","the","bloodstream","."),3992107). assertion_content_comment('oboGo_NorepinephrineEpinephrinevasoconstrictioninvolvedinregulationofsystemicarterialbloodpressure',s("A","process","that","results","in","a","decrease","in","the","diameter","of","an","artery","during","the","norepinephrine-epinephrine","response","to","decreased","blood","pressure","."),3992118). assertion_content_comment('oboGo_NorSpermidinebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","nor-spermidine",",","a","compound","related","to","spermidine",",","N-","(","3-aminopropyl",")","-1",",","4-diaminobutane","."),4298514). assertion_content_comment('oboGo_NorSpermidinecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","nor-spermidine",",","a","compound","related","to","spermidine",",","N-","(","3-aminopropyl",")","-1",",","4-diaminobutane","."),4354367). assertion_content_comment('oboGo_NorSpermidinemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","nor-spermidine",",","a","compound","related","to","spermidine",",","N-","(","3-aminopropyl",")","-1",",","4-diaminobutane","."),4298511). assertion_content_comment('oboGo_NOS2Cd74complex',s("A","protein","complex","comprising","nitric","oxide","synthase","2","and","CD74",".","This","stable","complex","formation","is","thought","to","prevent","CD74","degradation","by","caspases","."),4380336). assertion_content_comment('oboGo_NotchReceptorProcessingLigandDependent',s("The","proteolytic","cleavages","to","the","Notch","protein","that","occur","as","a","result","of","ligand","binding",".","Ligand","binding","at","the","cell","surface","exposes","an","otherwise","inaccessible","cleavage","site","in","the","extracellular","portion","of","Notch",",","which","when","cleaved","releases","a","membrane-tethered","form","of","the","Notch","intracellular","domain",".","Subsequent","cleavage","within","the","transmembrane","domain","then","leads","to","the","release","of","the","soluble","Notch","intracellular","domain","(","NICD",")"),4083572). assertion_content_comment('oboGo_NotchReceptorProcessingLigandIndependent',s("The","proteolytic","cleavages","to","the","Notch","protein","that","occur","prior","to","ligand","binding",".","A","primary","cleavage","event","within","the","extracellular","domain","whilst","the","Notch","protein","in","still","in","the","secretory","pathway",",","leads","to","the","transportation","of","a","processed","heterodimer","to","the","cell","surface","."),4083540). assertion_content_comment('oboGo_NotchSignalingPathwayInvolvedInCameraTypeeyephotoreceptorfatecommitment',s("The","series","of","molecular","signals","initiated","by","binding","of","an","extracellular","ligand","to","a","Notch","receptor","on","the","surface","of","the","target","cell","that","contributes","to","the","commitment","of","a","precursor","cell","to","a","eye","photoreceptor","fate","."),4115443). assertion_content_comment('oboGo_NPalmitoyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","palmitoyl","group","to","a","nitrogen","atom","on","the","acceptor","molecule","."),4237091). assertion_content_comment('oboGo_NSubstitutedformamidedeformylaseactivity',s("Catalysis","of","the","reaction",":","N-benzylformamide","+","H2O","=","formate","+","benzylamine","."),4345122). assertion_content_comment('oboGo_NSuccinylargininedihydrolaseactivity',s("Catalysis","of","the","reaction",":","N","(","2",")","-succinyl-L-arginine","+","2","H","(","2",")","O","+","2","H","(","+",")","=","N","(","2",")","-succinyl-L-ornithine","+","CO","(","2",")","+","2","NH","(","4",")","(","+",")"),4256550). assertion_content_comment('oboGo_NSuccinyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","succinyl","group","to","a","nitrogen","atom","on","the","acceptor","molecule","."),4189559). assertion_content_comment('oboGo_N_Sulfoglucosamine_3_SulfataseActivity',s("Catalysis","of","the","hydrolysis","of","the","3-sulfate","groups","of","the","N-sulfo-D-glucosamine","3-O-sulfate","units","of","heparin","."),4344068). assertion_content_comment('oboGo_NSulfoglucosaminesulfohydrolaseactivity',s("Catalysis","of","the","reaction",":","N-sulfo-D-glucosamine","+","H2O","=","D-glucosamine","+","sulfate","."),4303724). assertion_content_comment('oboGo_NTerminalarginineaminopeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","hydrolysis","of","an","arginine","residue","from","the","N-terminal","of","an","oligopeptide","or","polypeptide","chain","."),4286331). assertion_content_comment('oboGo_NTerminalbasicaminoacidaminopeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","hydrolysis","of","basic","amino","acid","residues","at","the","N-terminal","of","an","oligopeptide","or","polypeptide","chain","."),4286285). assertion_content_comment('oboGo_NTerminallysineaminopeptidaseactivity',s("OBSOLETE",".","Catalysis","of","the","hydrolysis","of","a","lysine","residue","from","the","N-terminal","of","an","oligopeptide","or","polypeptide","chain","."),4286272). assertion_content_comment('oboGo_NTerminalmyristoylationdomainbinding',s("Interacting","selectively","and","non-covalently","with","the","N-terminus","of","a","protein","that","has","the","potential","to","be",",","or","has","been",",","modified","by","N-terminal","myristoylation",".","Binding","affinity","is","typically","altered","by","myristoylation",";","for","example",",","N-terminal","myristoylation","of","HIV","Nef","increases","its","affinity","for","calmodulin","."),4320547). assertion_content_comment('oboGo_NTerminalpeptidylAlanineacetylation',s("The","acetylation","of","the","N-terminal","alanine","of","proteins",";","catalyzed","by","peptide","alpha-N-acetyltransferase","or","other","enzymes","of","this","class",",","such","as","ribosomal-protein-alanine","N-acetyltransferase","."),4258401). assertion_content_comment('oboGo_NTerminalpeptidylAlaninemethylation',s("The","methylation","of","the","N-terminal","alanine","of","proteins","."),4245156). assertion_content_comment('oboGo_NTerminalpeptidylAlaninemonomethylation',s("The","monomethylation","of","the","N-terminal","alanine","of","proteins","to","form","the","derivative","peptidyl-N-methyl-L-alanine","."),4245158). assertion_content_comment('oboGo_NTerminalpeptidylAlaninenCarbamoylation',s("The","carbamylation","of","the","N-terminal","alanine","of","proteins","to","form","the","derivative","N-carbamoyl-L-alanine","."),4362068). assertion_content_comment('oboGo_NTerminalpeptidylAlaninetrimethylation',s("The","trimethylation","of","the","N-terminal","alanine","of","proteins","to","form","the","derivative","peptidyl-N",",","N",",","N-trimethyl-L-alanine","."),4283434). assertion_content_comment('oboGo_NTerminalpeptidylAminoaciddeaminationtopyruvicacid',s("The","oxidative","deamination","of","N-terminal","peptidyl-cysteine",",","or","peptidyl-serine",",","to","form","pyruvic","acid","with","an","amide","bond","between","its","1-carboxyl","group","and","the","N-terminal","residue","."),4282870). assertion_content_comment('oboGo_NTerminalpeptidylArginineacetylation',s("The","acetylation","of","the","N-terminal","arginine","of","proteins",";","catalyzed","by","an","uncharacterized","arginyl-peptide","alpha-N-acetyltransferase","."),4384774). assertion_content_comment('oboGo_NTerminalpeptidylAsparaginedeamination',s("The","removal","of","an","amino","group","from","the","side","chain","of","an","N-terminal","asparagine","residue","of","a","protein","."),4319681). assertion_content_comment('oboGo_NTerminalpeptidylAsparticacidacetylation',s("The","acetylation","of","the","N-terminal","aspartic","acid","of","proteins",";","catalyzed","by","aspartate","N-acetyltransferase","."),4258211). assertion_content_comment('oboGo_NTerminalpeptidylCysteineacetylation',s("The","acetylation","of","the","N-terminal","cysteine","of","proteins","to","form","the","derivative","N-acetyl-L-cysteine","."),4280581). assertion_content_comment('oboGo_NTerminalpeptidylCysteinecondensationwithpyruvatetoformnPyruvicacid2IminylLCysteine',s("The","condensation","of","pyruvate","through","the","2-oxo","group","with","the","N-terminal","cysteine","of","proteins","to","form","the","derivative","N-pyruvic","acid","2-iminyl-L-cysteine","."),4282880). assertion_content_comment('oboGo_NTerminalpeptidylCysteinedeamination',s("The","oxidative","deamination","of","N-terminal","peptidyl-cysteine","to","form","pyruvic","acid","with","an","amide","bond","between","its","1-carboxyl","group","and","the","N-terminal","residue","."),4284229). assertion_content_comment('oboGo_NTerminalpeptidylGlutamicacidacetylation',s("The","acetylation","of","the","N-terminal","glutamic","acid","of","proteins",";","catalyzed","by","peptide","alpha-N-acetyltransferase","."),4283643). assertion_content_comment('oboGo_NTerminalpeptidylGlutamineacetylation',s("The","acetylation","of","a","glutamine","residue","in","protein","to","form","the","N5-methyl-L-glutamine","derivative",".","The","occurrence","of","this","modification","has","not","been","confirmed",".","Its","annotation","in","sequence","databases","is","either","due","to","the","misidentification","of","2-pyrrolidone-5-carboxylic","acid",",","or","to","inappropriate","homolog","comparisons","when","proteolytic","modification","is","more","probable","."),4258167). assertion_content_comment('oboGo_NTerminalpeptidylGlutaminedeamination',s("The","removal","of","an","amino","group","from","the","side","chain","of","an","N-terminal","glutamine","residue","of","a","protein","."),4319672). assertion_content_comment('oboGo_NTerminalpeptidylGlutaminemethylation',s("The","methylation","of","a","glutamine","residue","in","proteins","to","form","the","peptidyl-N5-methyl-L-glutamine","derivative","."),4283478). assertion_content_comment('oboGo_NTerminalpeptidylGlycineacetylation',s("The","acetylation","of","the","N-terminal","glycine","of","proteins","to","form","the","derivative","N-acetylglycine","."),4258199). assertion_content_comment('oboGo_NTerminalpeptidylGlycinemethylation',s("The","methylation","of","the","N-terminal","glycine","of","proteins","to","form","the","derivative","N-methylglycine","."),4283445). assertion_content_comment('oboGo_NTerminalpeptidylGlycinenFormylation',s("The","formylation","of","the","N-terminal","glycine","of","proteins","to","form","the","derivative","N-formylglycine","."),4283631). assertion_content_comment('oboGo_NTerminalpeptidylGlycinenGlucuronylation',s("The","glucuronylation","of","the","N-terminal","glycine","of","proteins","to","form","the","derivative","D-glucuronyl-N-glycine","."),4283699). assertion_content_comment('oboGo_NTerminalpeptidylGlycinenMyristoylation',s("The","myristoylation","of","the","N-terminal","glycine","of","proteins","to","form","the","derivative","N-myristoyl-glycine","."),4283665). assertion_content_comment('oboGo_NTerminalpeptidylGlycinenPalmitoylation',s("The","covalent","attachment","of","a","palmitoyl","group","to","a","nitrogen","(","N",")","atom","in","an","N-terminal","glycine","residue","to","form","N-palmitoyl-glycine","."),4362217). assertion_content_comment('oboGo_NTerminalpeptidylIsoleucineacetylation',s("The","acetylation","of","the","N-terminal","isoleucine","of","proteins","to","form","the","derivative","N-acetyl-L-isoleucine",".","The","occurrence","of","this","modification","has","not","been","confirmed","."),4258188). assertion_content_comment('oboGo_NTerminalpeptidylIsoleucinemethylation',s("The","methylation","of","the","N-terminal","isoleucine","of","proteins","to","form","the","derivative","N-methyl-L-isoleucine","."),4357264). assertion_content_comment('oboGo_NTerminalpeptidylLCysteinenPalmitoylation',s("The","covalent","attachment","of","a","palmitoyl","group","to","a","nitrogen","(","N",")","atom","in","an","N-terminal","cysteine","residue","to","form","N-palmitoyl-L-cysteine","."),4283677). assertion_content_comment('oboGo_NTerminalpeptidylLeucinemethylation',s("The","methylation","of","the","N-terminal","leucine","of","proteins","to","form","the","derivative","N-methyl-L-leucine","."),4357201). assertion_content_comment('oboGo_NTerminalpeptidylLysineacetylation',s("The","acetylation","of","the","N-terminal","lysine","of","proteins","."),4258100). assertion_content_comment('oboGo_NTerminalpeptidylLysinen2Acetylation',s("The","acetylation","of","the","N-terminal","lysine","of","proteins","to","form","the","derivative","N2-acetyl-L-lysine",".","The","occurrence","of","this","modification","has","not","been","confirmed","."),4258102). assertion_content_comment('oboGo_NTerminalpeptidylMethionineacetylation',s("The","acetylation","of","the","N-terminal","methionine","of","proteins","to","form","the","derivative","N-acetyl-L-methionine","."),4258123). assertion_content_comment('oboGo_NTerminalpeptidylMethioninecarboxylation',s("The","carboxylation","of","the","N-terminal","methionine","of","proteins","to","form","the","derivative","N-carboxy-L-methionine","."),4272988). assertion_content_comment('oboGo_NTerminalpeptidylMethioninemethylation',s("The","methylation","of","the","N-terminal","methionine","of","proteins","to","form","the","derivative","N-methyl-L-methionine","."),4283456). assertion_content_comment('oboGo_NTerminalpeptidylPhenylalaninemethylation',s("The","methylation","of","the","N-terminal","phenylalanine","of","proteins","to","form","the","derivative","N-methyl-L-phenylalanine","."),4283467). assertion_content_comment('oboGo_NTerminalpeptidylProlineacetylation',s("The","acetylation","of","the","N-terminal","proline","of","proteins","to","form","the","derivative","N-acetyl-L-proline","."),4258134). assertion_content_comment('oboGo_NTerminalpeptidylProlinedimethylationinvolvedintranslation',s("An","N-terminal","peptidyl-proline","dimethylation","process","that","contributes","to","translation","."),4125460). assertion_content_comment('oboGo_NTerminalpeptidylProlinedimethylation',s("The","methylation","of","the","N-terminal","proline","of","proteins","to","form","the","derivative","N",",","N-dimethyl-L-proline","."),4125457). assertion_content_comment('oboGo_NTerminalpeptidylProlinemethylation',s("The","methylation","of","the","N-terminal","proline","of","proteins","."),4125455). assertion_content_comment('oboGo_NTerminalpeptidylProlinenFormylation',s("The","formylation","of","the","N-terminal","proline","of","proteins","to","form","the","derivative","N-formylproline","."),4285845). assertion_content_comment('oboGo_NTerminalpeptidylProlinetrimethylation',s("The","trimethylation","of","the","N-terminal","proline","of","proteins","to","form","the","derivative","N",",","N",",","N-trimethylproline","."),4378508). assertion_content_comment('oboGo_NTerminalpeptidylSerineacetylation',s("The","acetylation","of","the","N-terminal","serine","of","proteins","to","form","the","derivative","N-acetyl-L-serine","."),4258156). assertion_content_comment('oboGo_NTerminalpeptidylSerinedeamination',s("The","oxidative","deamination","of","N-terminal","peptidyl-serine","to","form","pyruvic","acid","with","an","amide","bond","between","its","1-carboxyl","group","and","the","N-terminal","residue","."),4283165). assertion_content_comment('oboGo_NTerminalpeptidylSerinedimethylation',s("The","dimethylation","of","the","N-terminal","serine","of","proteins","to","form","the","derivative","N",",","N-dimethylserine","."),4378478). assertion_content_comment('oboGo_NTerminalpeptidylSerinemethylation',s("The","methylation","of","the","N-terminal","serine","of","proteins","."),4378361). assertion_content_comment('oboGo_NTerminalpeptidylSerinemonomethylation',s("The","monomethylation","of","the","N-terminal","serine","of","proteins","to","form","the","derivative","N-methylserine","."),4378487). assertion_content_comment('oboGo_NTerminalpeptidylSerinetrimethylation',s("The","trimethylation","of","the","N-terminal","serine","of","proteins","to","form","the","derivative","N",",","N",",","N-trimethylserine","."),4378363). assertion_content_comment('oboGo_NTerminalpeptidylThreonineacetylation',s("The","acetylation","of","the","N-terminal","threonine","of","proteins","to","form","the","derivative","N-acetyl-L-threonine",";","catalyzed","by","peptide","alpha-N-acetyltransferase","."),4258081). assertion_content_comment('oboGo_NTerminalpeptidylThreoninedeamination',s("The","deamination","of","N-terminal","peptidyl-threonine","to","form","peptidyl-2-oxobutanoic","acid","."),4280546). assertion_content_comment('oboGo_NTerminalpeptidylTyrosineacetylation',s("The","acetylation","of","the","N-terminal","tyrosine","of","proteins","to","form","the","derivative","N-acetyl-L-tyrosine","."),4283598). assertion_content_comment('oboGo_NTerminalpeptidylTyrosinemethylation',s("The","methylation","of","the","N-terminal","tyrosine","of","proteins","to","form","the","derivative","N-methyl-L-tyrosine","."),4357190). assertion_content_comment('oboGo_NTerminalpeptidylValineacetylation',s("The","acetylation","of","the","N-terminal","tyrosine","of","proteins","to","form","the","derivative","N-acetyl-L-valine","."),4283609). assertion_content_comment('oboGo_NTerminalpeptidylValinecondensationwithpyruvatetoformnPyruvicacid2IminylLValine',s("The","condensation","of","pyruvate","through","the","2-oxo","group","with","the","N-terminal","valine","of","proteins","to","form","the","derivative","N-pyruvic","acid","2-iminyl-L-valine","."),4282860). assertion_content_comment('oboGo_NTerminalpeptidylValinedeamination',s("The","deamination","of","the","N-terminal","valine","residue","of","a","protein","to","form","isobutyrate","."),4282839). assertion_content_comment('oboGo_NTerminalproteinacetyltransferasecomplex',s("A","complex","that","catalyzes","the","transfer","of","an","acetyl","group","to","the","N-terminal","residue","of","a","protein","acceptor","molecule","."),4319446). assertion_content_comment('oboGo_NTerminalproteinaminoacidacetylation',s("The","acetylation","of","the","N-terminal","amino","acid","of","proteins","."),4223917). assertion_content_comment('oboGo_NTerminalproteinaminoacidcarbamoylation',s("The","carbamoylation","of","the","N-terminal","amino","acid","of","proteins","."),4273032). assertion_content_comment('oboGo_NTerminalproteinaminoacidcarboxylation',s("The","carboxylation","of","the","N-terminal","amino","acid","of","proteins","."),4272986). assertion_content_comment('oboGo_NTerminalproteinaminoaciddeaminationfromaminocarbon',s("The","oxidative","deamination","of","the","alpha","carbon","of","an","encoded","N-terminal","amino","acid",",","to","form","pyruvic","acid","retaining","an","amide","bond","between","its","1-carboxyl","group","and","the","adjacent","residue",".","The","pyruvate","2-oxo","group","may","become","an","enzyme","active","site",",","or","it","may","be","reduced","to","an","alcohol","."),4280543). assertion_content_comment('oboGo_NTerminalproteinaminoaciddeaminationfromsidechain',s("The","removal","of","an","amino","group","from","the","side","chain","of","an","N-terminal","asparagine","or","glutamine","residue","of","a","protein","."),4319670). assertion_content_comment('oboGo_NTerminalproteinaminoaciddeamination',s("The","removal","of","an","amino","group","from","the","N-terminal","amino","acid","residue","of","a","protein","."),4280541). assertion_content_comment('oboGo_NTerminalproteinaminoacidglucuronylation',s("The","glucuronylation","of","the","N-terminal","amino","acid","of","proteins","."),4283688). assertion_content_comment('oboGo_NTerminalproteinaminoacidmethylation',s("The","methylation","of","the","N-terminal","amino","acid","of","a","protein","."),4125442). assertion_content_comment('oboGo_NTerminalproteinaminoacidmodification',s("The","alteration","of","the","N-terminal","amino","acid","residue","in","a","protein","."),4116046). assertion_content_comment('oboGo_NTerminalproteinaminoacidnLinkedglycosylation',s("Addition","of","a","sugar","unit","via","a","nitrogen","(","N",")","atom","of","the","N-terminal","amino","acid","of","a","protein","."),4231108). assertion_content_comment('oboGo_NTerminalproteinformylation',s("The","formylation","of","the","N-terminal","amino","acid","of","proteins","."),4283620). assertion_content_comment('oboGo_NTerminalproteinlipidation',s("The","covalent","attachment","of","a","lipid","group","to","the","amino","terminus","of","a","protein","."),4116050). assertion_content_comment('oboGo_NTerminalproteinmyristoylation',s("The","covalent","attachment","of","a","myristoyl","group","to","the","N-terminal","amino","acid","residue","of","a","protein","."),4231087). assertion_content_comment('oboGo_NTerminalproteinnMethyltransferaseactivity',s("Catalysis","of","the","transfer","of","a","methyl","group","from","S-adenosyl-L-methionine","(","AdoMet",")","to","the","alpha-amino","group","of","the","N-terminal","amino","or","imino","acid","residue","of","a","protein","substrate",".","For","example",",","yeast","Tae1p","and","mammalian","family","member","METTL11A","preferentially","modify","the","N-terminal","residue","of","substrates","with","the","N-terminal","sequence","X-Pro-Lys",",","where","X","can","be","Pro",",","Ala",",","or","Ser","."),4170727). assertion_content_comment('oboGo_NTerminalproteinpalmitoylation',s("The","covalent","attachment","of","a","palmitoyl","group","to","the","N-terminal","amino","acid","residue","of","a","protein","."),4116067). assertion_content_comment('oboGo_Nuatigenin3BetaGlucosyltransferaseactivity',s("Catalysis","of","the","reaction",":","nuatigenin","+","UDP-D-glucose","=","H","(","+",")","+","nuatigenin","3-beta-D-glucopyranoside","+","UDP","."),4366762). assertion_content_comment('oboGo_NuclearCyclinDependentproteinkinaseholoenzymecomplex',s("Cyclin-dependent","protein","kinase","(","CDK",")","complex","found","in","the","nucleus","."),4232838). assertion_content_comment('oboGo_NuclearDNADirectedrnapolymerasecomplex',s("A","protein","complex",",","located","in","the","nucleus",",","that","possesses","DNA-directed","RNA","polymerase","activity","."),4006723). assertion_content_comment('oboGo_NuclearMRNA3Splicesiterecognition',s("Recognition","of","the","intron","3","'","-splice","site","by","components","of","the","assembling","U2-","or","U12-type","spliceosome","."),4074672). assertion_content_comment('oboGo_NuclearMRNA5Splicesiterecognition',s("Recognition","of","the","intron","5","'","-splice","site","by","components","of","the","assembling","spliceosome","."),3975986). assertion_content_comment('oboGo_NuclearMRNASurveillanceOfMRNA3Endprocessing',s("The","set","of","processes","involved","in","identifying","and","degrading","mRNAs","with","incorrectly","formed","3","'","-ends","within","the","nucleus","."),4128662). assertion_content_comment('oboGo_NuclearMRNASurveillanceOfSpliceosomalPreMrnasplicing',s("The","set","of","processes","involved","in","identifying","and","degrading","incorrectly","spliced","pre-mRNAs","within","the","nucleus","."),4128631). assertion_content_comment('oboGo_NuclearOuterMembraneEndoplasmicreticulummembranenetwork',s("The","continuous","network","of","membranes","encompassing","the","nuclear","outer","membrane","and","the","endoplasmic","reticulum","membrane","."),3978861). assertion_content_comment('oboGo_NuclearPolyadenylationDependentantisensetranscriptcatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","an","antisense","transcript",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","antisense","transcript","."),4167451). assertion_content_comment('oboGo_NuclearPolyadenylationDependentcutcatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","cryptic","unstable","transcript","(","CUT",")",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","CUT","."),4167472). assertion_content_comment('oboGo_NuclearPolyadenylationDependentmrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","messenger","RNA","(","mRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","mRNA","."),4167432). assertion_content_comment('oboGo_NuclearPolyadenylationDependentncrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","noncoding","RNA","(","ncRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","ncRNA","."),4167220). assertion_content_comment('oboGo_NuclearPolyadenylationDependentrrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","ribosomal","RNA","(","rRNA",")","molecule",",","including","RNA","fragments","released","as","part","of","processing","the","primary","transcript","into","multiple","mature","rRNA","species",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","rRNA","."),4167520). assertion_content_comment('oboGo_NuclearPolyadenylationDependentsnornacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","small","nucleolar","RNA","(","snoRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","snoRNA","."),4167576). assertion_content_comment('oboGo_NuclearPolyadenylationDependentsnrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","a","small","nuclear","RNA","(","snRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","snRNA","."),4167553). assertion_content_comment('oboGo_NuclearPolyadenylationDependenttrnacatabolicprocess',s("The","chemical","reactions","and","pathways","occurring","in","the","nucleus","and","resulting","in","the","breakdown","of","an","aberrant","or","incorrectly","modified","transfer","RNA","(","tRNA",")","molecule",",","initiated","by","the","enzymatic","addition","of","a","sequence","of","adenylyl","residues","(","polyadenylation",")","at","the","3","'","end","the","target","tRNA","."),4167496). assertion_content_comment('oboGo_NuclearProteasomeCoreComplexAlphaSubunitcomplex',s("The","subunits","forming","the","outer","ring","of","the","core","complex","of","a","proteasome","located","in","the","nucleus","of","a","cell","."),4060262). assertion_content_comment('oboGo_NuclearProteasomeCoreComplexBetaSubunitcomplex',s("The","subunits","forming","the","inner","ring","of","the","core","complex","of","a","proteasome","located","in","the","nucleus","of","a","cell","."),4060284). assertion_content_comment('oboGo_NuclearRetentionOfPreMrnaatthesiteoftranscription',s("The","process","involved","in","retention","of","aberrant","or","improperly","formed","mRNAs",",","e.g",".","those","that","are","incorrectly","or","incompletely","spliced","or","that","have","incorrectly","formed","3","'","-ends",",","within","the","nucleus","at","the","site","of","transcription","."),4128650). assertion_content_comment('oboGo_NuclearRetentionOfPreMrnawithaberrant3Endsatthesiteoftranscription',s("The","process","involved","in","retention","of","mRNAs","that","have","incorrectly","formed","3","'","-ends","within","the","nucleus","at","the","site","of","transcription","."),4128674). assertion_content_comment('oboGo_NuclearRetentionOfUnsplicedPreMrnaatthesiteoftranscription',s("The","process","involved","in","retention","of","incorrectly","or","incompletely","spliced","pre-mRNA","within","the","nucleus","at","the","site","of","transcription","."),4128653). assertion_content_comment('oboGo_NuclearRNADirectedrnapolymerasecomplex',s("A","complex","required","for","RNAi","mediated","heterochromatin","assembly",".","In","S",".","pombe","this","contains","RNA-directed","RNA","polymerase",",","a","putative","helicase","and","a","protein","containing","a","pap25","associated","domain","."),4319850). assertion_content_comment('oboGo_Nuclear_TranscribedMRNACatabolicProcess3_5ExonucleolyticNonsense_MediatedDecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","nuclear-transcribed","mRNA","transcript","body","of","an","mRNA","in","which","an","amino-acid","codon","has","changed","to","a","nonsense","codon",";","occurs","when","the","3","'","end","is","not","protected","by","a","3","'","-poly","(","A",")","tail",";","degradation","proceeds","in","the","3","'","to","5","'","direction","."),4175915). assertion_content_comment('oboGo_Nuclear_TranscribedMRNACatabolicProcess5_3ExonucleolyticNonsense_MediatedDecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","nuclear-transcribed","mRNA","transcript","body","of","an","mRNA","in","which","an","amino-acid","codon","has","changed","to","a","nonsense","codon",";","occurs","when","the","5","'","end","is","not","protected","by","a","5","'","-cap",";","degradation","proceeds","in","the","5","'","to","3","'","direction","."),4175942). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessdeadenylationDependentdecay',s("A","major","pathway","of","degradation","of","nuclear-transcribed","mRNAs","that","proceeds","through","a","series","of","ordered","steps","that","includes","poly","(","A",")","tail","shortening","and","that","can","regulate","mRNA","stability","."),3974296). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessdeadenylationIndependentdecay',s("A","pathway","of","degradation","of","nuclear-transcribed","mRNAs","that","proceeds","through","a","series","of","steps","that","is","independent","of","deadenylation",",","but","requires","decapping","followed","by","transcript","decay",",","and","that","can","regulate","mRNA","stability","."),4175852). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessendonucleolyticcleavageDependentdecay',s("A","minor","degradation","pathway","nuclear-transcribed","mRNAs","that","begins","with","an","endonucleolytic","cleavage","to","generate","unprotected","ends","."),4096401). assertion_content_comment('oboGo_Nuclear_TranscribedMRNACatabolicProcessExonucleolytic3_5',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","mRNA","transcript","body","that","occurs","when","the","3","'","end","is","not","protected","by","a","3","'","-poly","(","A",")","tail",";","degradation","proceeds","in","the","3","'","to","5","'","direction","."),4175911). assertion_content_comment('oboGo_Nuclear_TranscribedMRNACatabolicProcessExonucleolytic5_3',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","mRNA","transcript","body","that","occurs","when","the","5","'","end","is","not","protected","by","a","5","'","-cap",";","degradation","proceeds","in","the","5","'","to","3","'","direction","."),4175938). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessexonucleolytic',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","that","occurs","when","the","ends","are","not","protected","by","the","5","'","-cap","or","the","3","'","-poly","(","A",")","tail","."),4096385). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessmeiosisSpecifictranscripts',s("The","chemical","reactions","and","pathways","resulting","in","the","selective","degradation","of","meiosis-specific","transcripts","during","vegetative","growth",",","by","a","mechanism","that","requires","determinant","of","selective","removal","(","DSR",")","sequences","in","the","targeted","mRNAs","and","involves","a","YTH","family","protein","."),4341614). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessnoGodecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","with","stalls","in","translation","elongation","."),4178039). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessnonsenseMediateddecay',s("The","nonsense-mediated","decay","pathway","for","nuclear-transcribed","mRNAs","degrades","mRNAs","in","which","an","amino-acid","codon","has","changed","to","a","nonsense","codon",";","this","prevents","the","translation","of","such","mRNAs","into","truncated",",","and","potentially","harmful",",","proteins","."),4144061). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocessnonStopdecay',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","the","transcript","body","of","a","nuclear-transcribed","mRNA","that","is","lacking","a","stop","codon","."),4175829). assertion_content_comment('oboGo_NuclearTranscribedmrnacatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","nuclear-transcribed","mRNAs","in","eukaryotic","cells","."),3974291). assertion_content_comment('oboGo_NuclearTranscribedmrnapolyatailshortening',s("Shortening","of","the","poly","(","A",")","tail","of","a","nuclear-transcribed","mRNA","from","full","length","to","an","oligo","(","A",")","length","."),3974350). assertion_content_comment('oboGo_NucleicAcidProteincovalentcrossLinking',s("The","formation","of","a","covalent","cross-link","between","a","nucleic","acid","and","a","protein","."),4280304). assertion_content_comment('oboGo_NucleoproteinFilamentFormingatpaseactivity',s("OBSOLETE",".","Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate","to","drive","the","assembly","of","proteins","such","as","Rad51p","onto","single-stranded","(","ss",")","DNA","to","form","a","helical","nucleoprotein","filament","."),4347691). assertion_content_comment('oboGo_NucleosideDiphosphataseactivity',s("Catalysis","of","the","reaction",":","a","nucleoside","diphosphate","+","H2O","=","a","nucleotide","+","phosphate","."),4201853). assertion_content_comment('oboGo_NucleosideOxidaseHydrogenPeroxideFormingactivity',s("Catalysis","of","the","reactions",":","adenosine","+","2","O2","=","9-riburonosyladenine","+","2","hydrogen","peroxide",";","(","1a",")","adenosine","+","O2","=","5","'","-dehydroadenosine","+","hydrogen","peroxide",",","and","(","1b",")","5","'","-dehydroadenosine","+","O2","=","9-riburonosyladenine","+","hydrogen","peroxide","."),4341946). assertion_content_comment('oboGo_NucleosideSpecificchannelformingporinactivity',s("Enables","the","energy","independent","passage","of","nucleoside",",","sized","less","than","1000","Da",",","across","a","membrane",".","The","transmembrane","portions","of","porins","consist","exclusively","of","beta-strands","which","form","a","beta-barrel",".","They","are","found","in","the","outer","membranes","of","Gram-negative","bacteria",",","mitochondria",",","plastids","and","possibly","acid-fast","Gram-positive","bacteria","."),4292414). assertion_content_comment('oboGo_NucleosideTriphosphataseactivity',s("Catalysis","of","the","reaction",":","a","nucleoside","triphosphate","+","H2O","=","nucleoside","diphosphate","+","phosphate","."),4159553). assertion_content_comment('oboGo_NucleosideTriphosphataseregulatoractivity',s("Modulates","the","rate","of","NTP","hydrolysis","by","a","NTPase","."),4160776). assertion_content_comment('oboGo_NucleosideTriphosphatediphosphataseactivity',s("Catalysis","of","the","reaction",":","H2O","+","a","nucleoside","triphosphate","=","diphosphate","+","a","nucleotide","."),4210799). assertion_content_comment('oboGo_Nucleoside_Triphosphate_Hexose_1_PhosphateNucleotidyltransferaseActivity',s("Catalysis","of","the","reaction",":","hexose","1-phosphate","+","nucleoside","triphosphate","=","NDP-hexose","+","diphosphate","."),4368348). assertion_content_comment('oboGo_NucleosomeDependentatpaseactivity',s("Catalysis","of","the","reaction",":","ATP","+","H2O","=","ADP","+","phosphate",".","This","reaction","requires","the","presence","of","one","or","more","nucleosomes","."),4177128). assertion_content_comment('oboGo_NucleotideBindingoligomerizationdomaincontaining1signalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","nucleotide-binding","oligomerization","domain","containing","1","(","NOD1",")"),4136475). assertion_content_comment('oboGo_NucleotideBindingoligomerizationdomaincontaining2signalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","nucleotide-binding","oligomerization","domain","containing","2","(","NOD2",")"),4136385). assertion_content_comment('oboGo_NucleotideBindingoligomerizationdomaincontainingsignalingpathway',s("Any","series","of","molecular","signals","generated","as","a","consequence","of","binding","to","a","nucleotide-binding","oligomerization","domain","containing","(","NOD",")","protein","."),4136381). assertion_content_comment('oboGo_NucleotideExcisionrepaircomplex',s("Any","complex","formed","of","proteins","that","act","in","nucleotide-excision","repair","."),3976607). assertion_content_comment('oboGo_NucleotideExcisionrepairdnadamagerecognition',s("The","identification","of","lesions","in","DNA",",","such","as","pyrimidine-dimers",",","intrastrand","cross-links",",","and","bulky","adducts",".","The","wide","range","of","substrate","specificity","suggests","the","repair","complex","recognizes","distortions","in","the","DNA","helix","."),3976827). assertion_content_comment('oboGo_NucleotideExcisionrepairdnadamageremoval',s("The","removal","of","the","oligonucleotide","that","contains","the","DNA","damage",".","The","oligonucleotide","is","formed","by","dual","incisions","that","flank","the","site","of","DNA","damage","."),3976930). assertion_content_comment('oboGo_NucleotideExcisionrepairdnaduplexunwinding',s("The","unwinding",",","or","local","denaturation",",","of","the","DNA","duplex","to","create","a","bubble","around","the","site","of","the","DNA","damage","."),3976974). assertion_content_comment('oboGo_NucleotideExcisionrepairdnagapfilling',s("Repair","of","the","gap","in","the","DNA","helix","by","DNA","polymerase","and","DNA","ligase","after","the","portion","of","the","strand","containing","the","lesion","has","been","removed","by","pyrimidine-dimer","repair","enzymes","."),4011071). assertion_content_comment('oboGo_NucleotideExcisionrepairdnaincision3Tolesion',s("The","endonucleolytic","cleavage","of","the","damaged","strand","of","DNA","3","'","to","the","site","of","damage",".","The","incision","occurs","at","the","junction","of","single-stranded","DNA","and","double-stranded","DNA","that","is","formed","when","the","DNA","duplex","is","unwound",".","The","incision","precedes","the","incision","formed","5","'","to","the","site","of","damage","."),4223834). assertion_content_comment('oboGo_NucleotideExcisionrepairdnaincision5Tolesion',s("The","endonucleolytic","cleavage","of","the","damaged","strand","of","DNA","5","'","to","the","site","of","damage",".","The","incision","occurs","at","the","junction","of","single-stranded","DNA","and","double-stranded","DNA","that","is","formed","when","the","DNA","duplex","is","unwound",".","The","incision","follows","the","incision","formed","3","'","to","the","site","of","damage","."),4223845). assertion_content_comment('oboGo_NucleotideExcisionrepairdnaincision',s("A","process","that","results","in","the","endonucleolytic","cleavage","of","the","damaged","strand","of","DNA",".","The","incision","occurs","at","the","junction","of","single-stranded","DNA","and","double-stranded","DNA","that","is","formed","when","the","DNA","duplex","is","unwound","."),4063019). assertion_content_comment('oboGo_NucleotideExcisionrepairfactor1complex',s("One","of","several","protein","complexes","involved","in","nucleotide-excision","repair",";","possesses","DNA","damage","recognition","and","endodeoxynuclease","activities",".","In","S",".","cerevisiae",",","it","is","composed","of","Rad1p",",","Rad10p",",","and","Rad14p",";","in","human","the","subunits","are","ERCC4/XPF",",","ERCC1","and","XPA",",","respectively","."),4345839). assertion_content_comment('oboGo_NucleotideExcisionrepairfactor2complex',s("One","of","several","protein","complexes","involved","in","nucleotide-excision","repair",";","possesses","damaged","DNA","binding","activity",".","In","S",".","cerevisiae",",","it","is","composed","of","Rad4p","and","Rad23p","."),4345851). assertion_content_comment('oboGo_NucleotideExcisionrepairfactor3complex',s("One","of","several","protein","complexes","involved","in","nucleotide-excision","repair",";","possesses","endodeoxynuclease","and","DNA","helicase","activities",".","In","S",".","cerevisiae",",","it","is","composed","of","Rad2p","and","the","core","TFIIH-Ssl2p","complex","(","Core","TFIIH","is","composed","of","Rad3p",",","Tfb1p",",","Tfb2p",",","Ssl1p",",","and","Tfb4p",".","Note","that","Ssl2p","is","also","called","Rad25p",")"),3976609). assertion_content_comment('oboGo_NucleotideExcisionrepairfactor4complex',s("One","of","several","protein","complexes","involved","in","nucleotide-excision","repair",";","possesses","DNA","damage","recognition","and","DNA-dependent","ATPase","activities",".","In","S",".","cerevisiae",",","it","is","composed","of","Rad7p","and","Rad16p","."),4345862). assertion_content_comment('oboGo_NucleotideExcisionrepairpreincisioncomplexassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","proteins","on","DNA","to","form","the","multiprotein","complex","involved","in","damage","recognition",",","DNA","helix","unwinding",",","and","endonucleolytic","cleavage","at","the","site","of","DNA","damage",".","This","assembly","occurs","before","the","phosphodiester","backbone","of","the","damaged","strand","is","cleaved","3","'","and","5","'","of","the","site","of","DNA","damage","."),4010959). assertion_content_comment('oboGo_NucleotideExcisionrepairpreincisioncomplexstabilization',s("The","stabilization","of","the","multiprotein","complex","involved","in","damage","recognition",",","DNA","helix","unwinding",",","and","endonucleolytic","cleavage","at","the","site","of","DNA","damage","as","well","as","the","unwound","DNA",".","The","stabilization","of","the","protein-DNA","complex","ensures","proper","positioning","of","the","preincision","complex","before","the","phosphodiester","backbone","of","the","damaged","strand","is","cleaved","3","'","and","5","'","of","the","site","of","DNA","damage","."),4010971). assertion_content_comment('oboGo_NucleotideExcisionrepair',s("A","DNA","repair","process","in","which","a","small","region","of","the","strand","surrounding","the","damage","is","removed","from","the","DNA","helix","as","an","oligonucleotide",".","The","small","gap","left","in","the","DNA","helix","is","filled","in","by","the","sequential","action","of","DNA","polymerase","and","DNA","ligase",".","Nucleotide","excision","repair","recognizes","a","wide","range","of","substrates",",","including","damage","caused","by","UV","irradiation","(","pyrimidine","dimers","and","6-4","photoproducts",")","and","chemicals","(","intrastrand","cross-links","and","bulky","adducts",")"),3976812). assertion_content_comment('oboGo_NucleotideReceptorActivityGProteincoupled',s("A","GPCR","that","binds","a","nucleotide","or","nucleotide","derivative","as","its","ligand","."),4171638). assertion_content_comment('oboGo_NucleotideSugarbiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","nucleotide-sugars",",","any","nucleotide","in","which","the","distal","phosphoric","residue","of","a","nucleoside","5","'","-diphosphate","is","in","glycosidic","linkage","with","a","monosaccharide","or","monosaccharide","derivative","."),4187287). assertion_content_comment('oboGo_NucleotideSugarcatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","nucleotide-sugars",",","any","nucleotide","in","which","the","distal","phosphoric","residue","of","a","nucleoside","5","'","-diphosphate","is","in","glycosidic","linkage","with","a","monosaccharide","or","monosaccharide","derivative","."),4038144). assertion_content_comment('oboGo_NucleotideSugarmetabolicprocess',s("The","cellular","chemical","reactions","and","pathways","involving","nucleotide-sugars",",","any","nucleotide","in","which","the","distal","phosphoric","residue","of","a","nucleoside","5","'","-diphosphate","is","in","glycosidic","linkage","with","a","monosaccharide","or","monosaccharide","derivative","."),4038114). assertion_content_comment('oboGo_NucleotideSugartransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","a","nucleotide-sugar","from","one","side","of","the","membrane","to","the","other",".","A","nucleotide-sugar","is","any","nucleotide","in","which","the","distal","phosphoric","residue","of","a","nucleoside","5","'","-diphosphate","is","in","glycosidic","linkage","with","a","monosaccharide","or","monosaccharide","derivative","."),4216292). assertion_content_comment('oboGo_NucleotideSugartransport',s("The","directed","movement","of","nucleotide-sugars","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore",".","Nucleotide-sugars","are","any","nucleotide","in","which","the","distal","phosphoric","residue","of","a","nucleoside","5","'","-diphosphate","is","in","glycosidic","linkage","with","a","monosaccharide","or","monosaccharide","derivative","."),4158269). assertion_content_comment('oboGo_NucleotideSulfatetransmembranetransporteractivity',s("Catalysis","of","the","transfer","of","nucleotide-sulfate","from","one","side","of","a","membrane","to","the","other","."),4216352). assertion_content_comment('oboGo_NucleotideSulfatetransport',s("The","directed","movement","of","nucleotide","sulfate","into",",","out","of","or","within","a","cell",",","or","between","cells",",","by","means","of","some","agent","such","as","a","transporter","or","pore","."),4290573). assertion_content_comment('oboGo_NucleusAssociatedproteasomalubiquitinDependentproteincatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","misfolded","proteins","via","a","mechanism","in","which","the","proteins","are","transported","to","the","nucleus","for","ubiquitination",",","and","then","targeted","to","proteasomes","for","degradation","."),4172744). assertion_content_comment('oboGo_NucleusVacuolejunctionassembly',s("The","aggregation",",","arrangement","and","bonding","together","of","a","set","of","components","to","form","a","nucleus-vacuole","junction",",","which","are","membrane","contact","sites","formed","between","the","vacuole","membrane","and","the","outer","nuclear","membrane",".","In","S",".","cerevisiae","these","contacts","are","mediated","through","direct","physical","interaction","between","Vac8p","and","Nvj1p","."),4129854). assertion_content_comment('oboGo_NucleusVacuolejunction',s("An","organelle","membrane","contact","site","formed","between","the","vacuole","membrane","and","the","outer","nuclear","membrane",".","In","S",".","cerevisiae","these","contacts","are","mediated","through","direct","physical","interaction","between","Vac8p","and","Nvj1p","."),4171499). assertion_content_comment('oboGo_Number10Deacetylbaccatiniii10OAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","10-deacetylbaccatin","III","+","acetyl-CoA","=","baccatin","III","+","CoA","."),4277694). assertion_content_comment('oboGo_Number10Formyltetrahydrofolatebiosyntheticprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","formation","of","10-formyltetrahydrofolate",",","the","formylated","derivative","of","tetrahydrofolate","."),4257631). assertion_content_comment('oboGo_Number10Formyltetrahydrofolatecatabolicprocess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","10-formyltetrahydrofolate",",","the","formylated","derivative","of","tetrahydrofolate","."),4257673). assertion_content_comment('oboGo_Number10Formyltetrahydrofolatemetabolicprocess',s("The","chemical","reactions","and","pathways","involving","10-formyltetrahydrofolate",",","the","formylated","derivative","of","tetrahydrofolate","."),4257610). assertion_content_comment('oboGo_Number10Hydroxydihydrosanguinarine10OMethyltransferaseactivity',s("Catalysis","of","the","reaction",":","10-hydroxydihydrosanguinarine","+","S-adenosyl-L-methionine","(","1","+",")","=","S-adenosyl-L-homocysteine","+","dihydrochelirubine","+","H","(","+",")"),4309145). assertion_content_comment('oboGo_Number10HydroxytaxaneoAcetyltransferaseactivity',s("Catalysis","of","the","reaction",":","10-desacetyltaxuyunnanin","C","+","acetyl-CoA","=","CoA","+","taxuyunnanin","C","."),4277758). assertion_content_comment('oboGo_Number111_Trichloro_22_Bis_4_ChlorophenylEthaneCatabolicProcess',s("The","chemical","reactions","and","pathways","resulting","in","the","breakdown","of","1",",","1",",","1-trichloro-2",",","2-bis-","(","4-chlorophenyl",")","ethane","(","DDT",")",",","a","chlorinated","broad","spectrum","contact","insecticide","."),4313661).